==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=23-OCT-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE/HYDROLASE INHIBITOR 21-FEB-11 3QSD . COMPND 2 MOLECULE: CATHEPSIN B-LIKE PEPTIDASE (C01 FAMILY); . SOURCE 2 ORGANISM_SCIENTIFIC: SCHISTOSOMA MANSONI; . AUTHOR P.REZACOVA,A.JILKOVA,J.BRYNDA,M.HORN,M.MARES . 253 1 6 6 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 12158.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 155 61.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 7 2.8 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 45 17.8 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 21 8.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 26 10.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 43 17.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 3 1.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 0 1 0 0 1 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 5 2 0 1 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 71 A E 0 0 219 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 136.6 2.9 -7.9 -0.6 2 72 A I - 0 0 33 1,-0.0 4,-0.1 2,-0.0 161,-0.0 -0.713 360.0-132.5 -89.4 124.8 3.8 -4.4 0.4 3 73 A P - 0 0 51 0, 0.0 -1,-0.0 0, 0.0 3,-0.0 -0.348 21.8-112.3 -71.4 161.6 1.4 -1.7 -0.8 4 74 A S S S+ 0 0 92 1,-0.1 2,-0.3 -2,-0.0 -2,-0.0 0.784 101.8 21.2 -62.2 -28.7 2.7 1.5 -2.4 5 75 A S - 0 0 61 203,-0.1 2,-0.3 2,-0.0 203,-0.2 -0.976 65.1-179.6-139.4 153.4 1.5 3.5 0.6 6 76 A F E -A 207 0A 25 201,-2.5 201,-2.1 -2,-0.3 2,-0.4 -0.963 5.0-174.3-152.4 139.9 0.7 2.7 4.2 7 77 A D E >> -A 206 0A 39 -2,-0.3 3,-1.7 199,-0.2 4,-1.5 -0.939 16.1-155.5-138.0 114.1 -0.6 4.9 7.0 8 78 A S H 3> S+ 0 0 0 197,-2.5 4,-2.1 -2,-0.4 -1,-0.1 0.790 95.6 63.9 -57.4 -28.7 -0.9 3.4 10.5 9 79 A R H 34 S+ 0 0 75 1,-0.2 -1,-0.3 2,-0.2 10,-0.1 0.806 106.5 44.4 -65.8 -28.4 -3.5 6.0 11.4 10 80 A K H <4 S+ 0 0 170 -3,-1.7 -1,-0.2 1,-0.1 -2,-0.2 0.778 112.4 49.7 -84.5 -30.6 -5.8 4.5 8.7 11 81 A K H < S+ 0 0 102 -4,-1.5 -2,-0.2 1,-0.2 -3,-0.1 0.866 125.4 24.6 -74.6 -37.2 -5.2 0.9 9.6 12 82 A W >< + 0 0 43 -4,-2.1 3,-2.0 1,-0.1 6,-0.2 -0.487 67.2 156.2-127.7 59.8 -5.9 1.3 13.3 13 83 A P T 3 + 0 0 98 0, 0.0 -1,-0.1 0, 0.0 6,-0.1 0.690 67.4 70.9 -68.3 -14.4 -8.1 4.4 13.8 14 84 A R T 3 S+ 0 0 213 1,-0.1 2,-1.0 -3,-0.1 3,-0.1 0.660 82.6 80.9 -65.8 -17.9 -9.5 3.1 17.1 15 85 A a X - 0 0 8 -3,-2.0 3,-1.5 1,-0.2 4,-0.4 -0.791 65.6-168.1 -99.5 100.0 -6.1 3.8 18.6 16 86 A K G > S+ 0 0 177 -2,-1.0 3,-0.6 1,-0.3 -1,-0.2 0.729 77.9 67.4 -61.2 -25.8 -6.1 7.5 19.4 17 87 A S G > S+ 0 0 17 1,-0.2 3,-2.0 2,-0.2 -1,-0.3 0.822 85.1 70.8 -66.6 -27.5 -2.3 7.7 20.1 18 88 A I G < S+ 0 0 2 -3,-1.5 -1,-0.2 1,-0.3 -9,-0.2 0.869 104.9 38.2 -64.0 -35.7 -1.3 6.9 16.5 19 89 A A G < S+ 0 0 62 -3,-0.6 2,-0.5 -4,-0.4 -1,-0.3 0.112 94.4 109.7 -97.7 20.3 -2.5 10.3 15.2 20 90 A T < - 0 0 48 -3,-2.0 2,-0.4 17,-0.1 199,-0.0 -0.869 52.9-157.6-100.0 126.5 -1.3 12.2 18.3 21 91 A I - 0 0 30 -2,-0.5 203,-0.2 208,-0.1 2,-0.2 -0.860 13.6-161.2 -98.8 134.5 1.7 14.5 17.9 22 92 A R - 0 0 25 198,-0.4 201,-2.3 -2,-0.4 2,-0.4 -0.609 12.9-132.3-108.3 173.5 3.6 15.3 21.2 23 93 A D B -I 222 0B 14 199,-0.2 199,-0.2 -2,-0.2 82,-0.1 -0.968 6.5-165.5-132.7 113.9 6.1 18.1 22.2 24 94 A Q - 0 0 12 197,-2.8 5,-0.2 -2,-0.4 198,-0.1 0.564 32.7-158.9 -74.0 -8.6 9.3 17.2 24.0 25 95 A S - 0 0 3 196,-0.3 2,-2.0 83,-0.2 -1,-0.2 -0.212 54.9 -18.8 61.8-154.4 9.8 20.9 25.0 26 96 A R S S+ 0 0 48 80,-0.2 98,-3.3 2,-0.1 2,-0.3 -0.441 113.4 93.7 -85.6 60.8 13.2 22.3 26.0 27 97 A b S S- 0 0 4 -2,-2.0 2,-1.5 96,-0.2 45,-0.1 -0.977 79.0-125.0-154.7 137.1 14.7 18.9 26.7 28 98 A G B +j 72 0C 24 43,-2.5 45,-0.7 -2,-0.3 3,-0.4 -0.311 68.6 125.8 -83.3 53.8 16.7 16.4 24.5 29 99 A S >> + 0 0 0 -2,-1.5 4,-2.2 -5,-0.2 3,-1.0 0.069 17.8 123.1-101.9 25.4 14.3 13.6 25.2 30 100 A C H 3> S+ 0 0 15 1,-0.3 4,-2.8 2,-0.2 5,-0.3 0.884 72.8 60.4 -53.5 -39.5 13.5 12.7 21.6 31 101 A W H 3> S+ 0 0 4 -3,-0.4 4,-1.2 1,-0.2 -1,-0.3 0.883 108.1 42.8 -54.4 -39.7 14.6 9.1 22.5 32 102 A A H <> S+ 0 0 0 -3,-1.0 4,-2.8 2,-0.2 5,-0.2 0.832 113.5 52.4 -79.8 -32.7 11.9 8.8 25.2 33 103 A F H X S+ 0 0 5 -4,-2.2 4,-2.5 2,-0.2 5,-0.3 0.950 108.7 47.3 -70.4 -50.2 9.2 10.5 23.0 34 104 A G H X S+ 0 0 0 -4,-2.8 4,-1.9 167,-0.2 -1,-0.2 0.885 115.8 49.8 -58.0 -35.3 9.7 8.2 20.0 35 105 A A H X S+ 0 0 0 -4,-1.2 4,-2.9 -5,-0.3 5,-0.3 0.981 113.1 40.7 -65.7 -61.0 9.6 5.3 22.5 36 106 A V H X S+ 0 0 0 -4,-2.8 4,-2.3 1,-0.2 19,-0.5 0.848 115.0 53.7 -67.8 -26.3 6.5 6.1 24.5 37 107 A E H X S+ 0 0 5 -4,-2.5 4,-2.4 -5,-0.2 -1,-0.2 0.967 114.3 39.6 -66.5 -50.7 4.6 7.1 21.3 38 108 A A H X S+ 0 0 0 -4,-1.9 4,-2.8 -5,-0.3 -2,-0.2 0.867 116.3 52.0 -68.3 -33.2 5.3 3.9 19.5 39 109 A M H X S+ 0 0 0 -4,-2.9 4,-2.4 2,-0.2 -1,-0.2 0.882 109.5 50.0 -67.5 -37.2 4.7 1.9 22.7 40 110 A S H X S+ 0 0 0 -4,-2.3 4,-1.8 -5,-0.3 13,-0.3 0.951 113.1 46.7 -64.2 -46.2 1.4 3.6 23.2 41 111 A D H X S+ 0 0 0 -4,-2.4 4,-3.1 1,-0.2 -2,-0.2 0.949 115.5 44.8 -57.9 -52.4 0.4 2.8 19.6 42 112 A R H X S+ 0 0 0 -4,-2.8 4,-2.8 1,-0.2 5,-0.3 0.867 106.7 58.7 -69.1 -32.1 1.5 -0.9 19.8 43 113 A S H X S+ 0 0 0 -4,-2.4 4,-0.7 -5,-0.2 8,-0.5 0.925 114.9 38.2 -61.4 -38.3 -0.1 -1.4 23.2 44 114 A a H ><>S+ 0 0 2 -4,-1.8 5,-2.9 -5,-0.2 3,-0.5 0.943 118.6 46.7 -76.5 -50.7 -3.4 -0.5 21.6 45 115 A I H ><5S+ 0 0 19 -4,-3.1 3,-1.4 1,-0.2 -2,-0.2 0.955 115.9 44.7 -55.9 -47.6 -2.9 -2.2 18.2 46 116 A Q H 3<5S+ 0 0 27 -4,-2.8 -1,-0.2 1,-0.3 -2,-0.2 0.640 112.5 51.6 -81.1 -12.1 -1.6 -5.5 19.7 47 117 A S T X<5S- 0 0 31 -4,-0.7 3,-1.3 -3,-0.5 -1,-0.3 0.219 114.2-111.7-103.1 15.1 -4.3 -5.7 22.4 48 118 A G T < 5S- 0 0 75 -3,-1.4 -3,-0.2 1,-0.2 -2,-0.1 0.838 77.9 -51.1 58.8 30.8 -7.2 -5.2 19.9 49 119 A G T 3 - 0 0 0 33,-3.2 4,-1.5 1,-0.2 5,-0.2 -0.522 23.6-167.0 -74.7 114.0 4.2 8.9 30.2 57 127 A A H > S+ 0 0 3 -2,-0.6 4,-2.9 34,-0.4 5,-0.2 0.902 90.7 55.2 -62.5 -37.9 7.3 10.4 28.5 58 128 A V H > S+ 0 0 14 43,-0.4 4,-2.8 2,-0.2 5,-0.3 0.876 101.9 55.5 -69.8 -33.0 8.4 11.7 31.9 59 129 A D H > S+ 0 0 0 42,-0.3 4,-2.3 2,-0.2 5,-0.3 0.965 115.4 38.0 -61.8 -49.1 8.3 8.3 33.6 60 130 A L H X S+ 0 0 0 -4,-1.5 4,-1.9 1,-0.2 -2,-0.2 0.952 118.3 49.8 -64.9 -48.6 10.6 6.8 31.0 61 131 A L H < S+ 0 0 5 -4,-2.9 -2,-0.2 1,-0.2 -1,-0.2 0.889 120.6 34.5 -58.1 -40.7 12.8 9.9 30.8 62 132 A S H < S+ 0 0 22 -4,-2.8 67,-0.4 -5,-0.2 -1,-0.2 0.793 123.4 38.5 -89.2 -28.5 13.3 10.3 34.5 63 133 A c H < S+ 0 0 12 -4,-2.3 2,-1.0 -5,-0.3 -3,-0.2 0.640 83.5 95.8-106.2 -15.0 13.4 6.7 35.8 64 134 A d >< - 0 0 13 -4,-1.9 3,-0.8 -5,-0.3 6,-0.2 -0.691 47.4-176.4 -84.6 108.0 15.3 4.7 33.2 65 135 A E T 3 S+ 0 0 194 -2,-1.0 3,-0.3 1,-0.2 -1,-0.2 0.631 79.7 48.2 -71.5 -23.6 18.9 4.6 34.6 66 136 A S T 3 S+ 0 0 90 1,-0.2 -1,-0.2 12,-0.1 13,-0.1 0.314 87.5 85.9-103.4 6.4 20.4 2.7 31.6 67 137 A d S < S- 0 0 0 -3,-0.8 8,-1.6 1,-0.2 2,-0.4 0.305 95.5-110.3 -95.5 6.1 18.9 4.9 28.8 68 138 A G B -L 74 0E 38 -3,-0.3 -1,-0.2 6,-0.2 6,-0.2 -0.843 65.9 -17.5 112.1-137.9 21.6 7.6 28.8 69 139 A L > - 0 0 129 4,-2.3 3,-2.4 -2,-0.4 2,-0.3 0.056 68.4-142.5-111.4 21.0 21.6 11.2 29.8 70 140 A G T > S+ 0 0 5 1,-0.3 3,-1.5 2,-0.2 -1,-0.3 -0.340 88.9 15.0 66.0-117.7 17.9 12.1 30.0 71 141 A b T 3 S+ 0 0 1 -2,-0.3 -43,-2.5 1,-0.3 -1,-0.3 0.554 127.0 61.9 -71.0 -1.1 17.4 15.7 28.7 72 142 A E B < S-j 28 0C 132 -3,-2.4 -1,-0.3 1,-0.4 -2,-0.2 0.041 124.4 -78.5-107.5 21.6 20.9 15.4 27.2 73 143 A G < - 0 0 26 -3,-1.5 -4,-2.3 -45,-0.7 -1,-0.4 0.014 49.3-147.8 103.8 157.0 20.0 12.5 24.9 74 144 A G B -L 68 0E 30 -6,-0.2 2,-0.4 -5,-0.2 -6,-0.2 -0.672 17.3 -96.3-148.5-162.3 19.4 8.8 25.3 75 145 A I > - 0 0 88 -8,-1.6 4,-1.0 -2,-0.2 -9,-0.0 -0.985 18.6-145.1-139.5 132.1 19.6 5.3 23.7 76 146 A L H > S+ 0 0 27 -2,-0.4 4,-1.8 1,-0.2 3,-0.4 0.920 90.7 55.0 -73.9 -47.9 16.8 3.4 22.0 77 147 A G H > S+ 0 0 23 1,-0.2 4,-2.3 2,-0.2 -1,-0.2 0.926 108.7 47.9 -54.8 -50.7 17.4 -0.2 23.0 78 148 A P H > S+ 0 0 30 0, 0.0 4,-2.3 0, 0.0 -1,-0.2 0.819 106.5 59.9 -63.1 -26.9 17.5 0.3 26.7 79 149 A A H X S+ 0 0 0 -4,-1.0 4,-1.8 -3,-0.4 -2,-0.2 0.941 109.4 41.6 -64.0 -43.1 14.3 2.4 26.5 80 150 A W H X S+ 0 0 0 -4,-1.8 4,-1.8 1,-0.2 -1,-0.2 0.860 112.3 54.9 -73.8 -34.0 12.4 -0.6 25.0 81 151 A D H X S+ 0 0 92 -4,-2.3 4,-2.8 -5,-0.2 5,-0.3 0.893 106.0 53.1 -61.1 -39.5 14.1 -2.9 27.5 82 152 A Y H X>S+ 0 0 22 -4,-2.3 5,-2.3 1,-0.2 4,-2.3 0.922 106.7 52.3 -62.4 -43.5 12.8 -0.7 30.3 83 153 A W H <5S+ 0 0 0 -4,-1.8 65,-1.3 3,-0.2 -1,-0.2 0.893 112.8 45.2 -57.3 -43.0 9.3 -0.9 28.9 84 154 A V H <5S+ 0 0 39 -4,-1.8 -2,-0.2 63,-0.3 -1,-0.2 0.934 124.4 31.1 -65.3 -47.4 9.6 -4.7 28.9 85 155 A K H <5S+ 0 0 157 -4,-2.8 -3,-0.2 -5,-0.1 -2,-0.2 0.955 138.2 12.4 -82.7 -54.2 11.1 -5.1 32.4 86 156 A E T <5S- 0 0 71 -4,-2.3 -3,-0.2 -5,-0.3 -4,-0.1 0.722 93.3-144.3 -96.3 -30.5 9.7 -2.2 34.5 87 157 A G < - 0 0 0 -5,-2.3 2,-0.4 -6,-0.2 60,-0.3 -0.100 13.6-101.8 82.3 169.7 6.9 -0.9 32.3 88 158 A I B -M 146 0F 0 58,-2.2 58,-2.2 -5,-0.2 -31,-0.1 -0.993 26.3-132.3-133.2 139.5 5.8 2.7 31.9 89 159 A V - 0 0 0 -2,-0.4 -33,-3.2 56,-0.2 2,-0.2 -0.209 33.1 -90.8 -82.3 177.8 2.8 4.5 33.5 90 160 A T B +K 55 0D 12 -35,-0.3 11,-2.9 54,-0.2 -35,-0.3 -0.499 51.6 149.6 -84.2 156.9 0.3 6.7 31.8 91 161 A G - 0 0 1 -37,-2.7 -34,-0.4 9,-0.2 8,-0.2 -0.579 24.4-153.2 172.1 130.7 0.6 10.5 31.4 92 162 A S - 0 0 5 6,-2.5 11,-2.9 1,-0.3 -35,-0.1 -0.010 45.4 -58.9 -90.5-166.0 -0.4 13.2 28.9 93 163 A S > - 0 0 37 9,-0.2 4,-1.9 1,-0.1 5,-0.4 -0.266 52.2-105.2 -68.5 167.1 1.1 16.6 28.0 94 164 A K T 4 S+ 0 0 101 11,-0.5 -1,-0.1 1,-0.2 -2,-0.1 0.934 121.3 51.7 -57.3 -46.1 1.5 19.3 30.6 95 165 A E T 4 S+ 0 0 85 1,-0.2 -1,-0.2 2,-0.1 -3,-0.0 0.808 115.1 39.8 -66.5 -33.9 -1.5 21.2 29.2 96 166 A N T 4 S- 0 0 106 2,-0.1 -1,-0.2 -3,-0.1 -2,-0.2 0.727 84.4-166.1 -86.3 -24.0 -3.8 18.2 29.2 97 167 A H < + 0 0 94 -4,-1.9 2,-0.3 1,-0.2 -3,-0.1 0.759 31.9 143.5 34.7 55.6 -2.6 16.9 32.6 98 168 A A + 0 0 46 -5,-0.4 -6,-2.5 3,-0.1 -1,-0.2 -0.731 37.6 24.7-112.4 159.1 -4.2 13.4 32.3 99 169 A G S S- 0 0 14 -2,-0.3 35,-0.4 -8,-0.2 -8,-0.2 -0.186 102.4 -51.9 83.7-172.5 -3.0 10.1 33.5 100 170 A e S S+ 0 0 0 1,-0.2 34,-2.5 33,-0.2 -9,-0.2 0.966 125.9 12.6 -70.0 -51.0 -0.5 9.1 36.2 101 171 A E S S- 0 0 14 -11,-2.9 -43,-0.4 32,-0.2 -42,-0.3 -0.748 73.0-164.9-135.6 84.8 2.5 11.4 35.3 102 172 A P - 0 0 26 0, 0.0 -9,-0.2 0, 0.0 -8,-0.1 -0.230 41.0 -86.3 -64.6 157.9 1.8 14.1 32.8 103 173 A Y - 0 0 12 -11,-2.9 -6,-0.2 1,-0.1 -11,-0.1 -0.431 32.5-146.6 -69.4 139.2 4.8 15.8 31.2 104 174 A P S S+ 0 0 58 0, 0.0 -1,-0.1 0, 0.0 -11,-0.1 0.571 70.8 79.4 -84.2 -7.3 6.2 18.7 33.3 105 175 A F S S- 0 0 25 -82,-0.1 -11,-0.5 1,-0.0 -82,-0.1 -0.804 75.5-120.4-112.5 144.4 7.4 20.9 30.5 106 176 A P - 0 0 39 0, 0.0 -80,-0.2 0, 0.0 -1,-0.0 -0.364 31.9 -92.9 -82.3 160.0 5.4 23.3 28.2 107 177 A K + 0 0 42 -82,-0.1 2,-0.3 -2,-0.1 115,-0.0 -0.284 49.6 171.8 -65.3 147.1 4.9 23.3 24.5 108 178 A f - 0 0 0 8,-0.1 2,-0.5 -83,-0.0 -83,-0.2 -0.979 37.8 -94.0-152.6 158.8 7.4 25.5 22.6 109 179 A E B -n 118 0G 7 8,-2.4 10,-2.9 -2,-0.3 2,-0.9 -0.691 31.8-150.0 -84.6 129.3 8.3 26.2 18.9 110 180 A H - 0 0 9 112,-0.5 3,-0.1 -2,-0.5 112,-0.1 -0.797 68.9 -42.8-101.2 94.5 11.2 24.2 17.7 111 181 A H S S+ 0 0 102 -2,-0.9 2,-0.3 1,-0.2 -1,-0.2 0.780 120.8 82.5 62.2 31.7 13.2 26.1 15.0 112 182 A T S S- 0 0 28 114,-0.0 2,-0.2 2,-0.0 -1,-0.2 -0.974 81.8 -91.2-161.4 164.1 10.0 27.3 13.3 113 183 A K + 0 0 191 -2,-0.3 2,-0.3 112,-0.1 -3,-0.1 -0.548 59.3 106.7 -86.0 147.2 7.3 29.9 13.4 114 184 A G S S- 0 0 48 -2,-0.2 -5,-0.1 2,-0.2 -2,-0.0 -0.987 72.8 -67.0 170.3-171.2 4.1 29.6 15.3 115 185 A K S S+ 0 0 135 -2,-0.3 -1,-0.1 -7,-0.1 -2,-0.0 0.523 95.6 83.7 -83.0 -10.1 1.8 30.4 18.2 116 186 A Y S S- 0 0 50 1,-0.1 -7,-0.2 -8,-0.0 -2,-0.2 -0.593 93.4 -89.9 -90.1 157.5 3.8 28.8 21.1 117 187 A P - 0 0 81 0, 0.0 -8,-2.4 0, 0.0 -1,-0.1 -0.321 55.5 -95.7 -56.8 144.1 6.7 30.5 22.9 118 188 A P B -n 109 0G 102 0, 0.0 -8,-0.2 0, 0.0 -5,-0.1 -0.312 24.0-133.3 -57.5 144.7 10.0 29.8 21.1 119 189 A f - 0 0 12 -10,-2.9 3,-0.2 1,-0.1 -9,-0.1 0.847 41.4-174.5 -67.2 -30.2 12.0 26.9 22.6 120 190 A G - 0 0 64 -11,-0.4 -1,-0.1 1,-0.2 -9,-0.1 -0.073 40.8 -62.4 57.6-166.7 15.2 29.0 22.6 121 191 A S S S+ 0 0 114 2,-0.1 -1,-0.2 -95,-0.0 2,-0.1 0.705 96.1 98.6 -93.9 -25.9 18.5 27.6 23.5 122 192 A K - 0 0 175 -3,-0.2 2,-0.4 1,-0.0 0, 0.0 -0.370 56.0-151.3 -70.8 145.0 18.3 26.6 27.3 123 193 A I - 0 0 77 -2,-0.1 -96,-0.2 -95,-0.0 2,-0.1 -0.940 15.1-124.6-117.1 135.1 17.7 22.9 28.1 124 194 A Y - 0 0 74 -98,-3.3 -96,-0.2 -2,-0.4 2,-0.1 -0.411 31.0-104.9 -71.6 154.7 15.9 21.8 31.3 125 195 A K - 0 0 180 1,-0.1 -1,-0.1 -2,-0.1 -55,-0.1 -0.461 49.9 -85.8 -73.5 151.8 17.6 19.4 33.7 126 196 A T - 0 0 58 -57,-0.2 -1,-0.1 -2,-0.1 -56,-0.0 -0.390 52.5-113.7 -56.1 131.4 16.3 15.8 33.6 127 197 A P - 0 0 25 0, 0.0 -1,-0.1 0, 0.0 2,-0.1 -0.249 33.3 -99.0 -63.7 157.2 13.3 15.6 35.9 128 198 A R - 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