==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=11-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HORMONE/GROWTH FACTOR RECEPTOR 29-JUN-99 1QTY . COMPND 2 MOLECULE: VASCULAR ENDOTHELIAL GROWTH FACTOR; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR C.WIESMANN,A.M.DE VOS . 757 8 20 16 4 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 38679.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 519 68.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 41 5.4 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 251 33.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 16 2.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 10 1.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 129 17.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 42 5.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 40 5.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 4 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 7 1 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 4 0 12 8 0 0 1 7 0 0 0 0 0 0 0 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 4 4 4 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 13 V E 0 0 214 0, 0.0 160,-0.6 0, 0.0 2,-0.4 0.000 360.0 360.0 360.0 133.2 1.7 22.1 25.8 2 14 V V E -a 161 0A 42 158,-0.1 2,-0.6 160,-0.1 160,-0.2 -0.835 360.0-124.1 -98.2 144.0 1.7 19.4 23.2 3 15 V V E -a 162 0A 19 158,-2.3 160,-2.8 -2,-0.4 157,-0.0 -0.763 33.1-119.5 -85.9 121.3 3.3 16.0 23.9 4 16 V K > - 0 0 112 -2,-0.6 4,-2.4 158,-0.2 3,-0.4 -0.282 19.1-114.7 -62.1 141.6 5.9 15.3 21.2 5 17 V F H > S+ 0 0 1 1,-0.2 4,-3.2 2,-0.2 5,-0.2 0.872 114.4 55.9 -42.6 -49.8 5.4 12.3 19.0 6 18 V M H > S+ 0 0 35 484,-0.2 4,-2.8 2,-0.2 5,-0.3 0.944 110.3 44.0 -52.0 -52.0 8.5 10.7 20.4 7 19 V D H > S+ 0 0 68 -3,-0.4 4,-3.0 1,-0.2 5,-0.3 0.976 114.2 48.8 -58.3 -56.7 7.4 10.9 24.0 8 20 V V H X S+ 0 0 0 -4,-2.4 4,-1.7 1,-0.2 -1,-0.2 0.904 115.0 47.6 -49.2 -43.7 3.9 9.8 23.2 9 21 V Y H X S+ 0 0 2 -4,-3.2 4,-1.4 -5,-0.3 -1,-0.2 0.911 115.5 40.2 -66.1 -48.8 5.3 6.8 21.3 10 22 V Q H < S+ 0 0 70 -4,-2.8 -2,-0.2 -5,-0.2 -1,-0.2 0.907 117.4 49.8 -68.1 -42.1 7.9 5.6 23.8 11 23 V R H < S+ 0 0 111 -4,-3.0 -2,-0.2 -5,-0.3 -1,-0.2 0.807 115.1 43.1 -66.8 -31.5 5.6 6.2 26.7 12 24 V S H < S+ 0 0 0 -4,-1.7 36,-1.6 -5,-0.3 -1,-0.2 0.685 88.6 114.6 -87.2 -22.4 2.7 4.3 25.1 13 25 V Y B < S-d 48 0B 18 -4,-1.4 36,-0.2 34,-0.2 33,-0.1 -0.212 84.5 -76.9 -58.8 137.0 4.7 1.4 23.7 14 26 V a S S+ 0 0 5 34,-2.4 33,-0.2 31,-0.1 -1,-0.2 0.021 76.9 128.8 -33.1 114.2 4.2 -2.2 25.1 15 27 V H E -E 46 0C 55 31,-2.5 31,-1.6 -3,-0.2 2,-0.5 -0.977 67.0 -74.4-164.6 163.1 5.9 -2.5 28.5 16 28 V P E +E 45 0C 36 0, 0.0 2,-0.3 0, 0.0 29,-0.3 -0.544 56.2 177.6 -71.1 121.6 5.0 -3.6 32.0 17 29 V I E -E 44 0C 21 27,-3.5 27,-2.6 -2,-0.5 2,-0.4 -0.928 38.9 -96.1-124.4 146.4 2.9 -0.9 33.6 18 30 V E E -E 43 0C 67 -2,-0.3 2,-0.3 25,-0.2 25,-0.2 -0.504 48.4-175.0 -64.9 124.3 1.2 -0.8 37.0 19 31 V T E -E 42 0C 50 23,-3.8 23,-3.8 -2,-0.4 2,-0.9 -0.914 26.8-129.8-120.7 144.2 -2.3 -2.0 36.6 20 32 V L E -E 41 0C 33 -2,-0.3 2,-0.4 21,-0.2 123,-0.2 -0.834 32.7-165.9-100.2 103.4 -5.1 -2.1 39.2 21 33 V V E -E 40 0C 10 19,-2.7 19,-3.3 -2,-0.9 2,-0.4 -0.737 20.8-121.1 -94.6 134.1 -6.4 -5.7 39.0 22 34 V D E >> -E 39 0C 62 -2,-0.4 4,-1.3 17,-0.3 3,-0.9 -0.581 17.3-139.5 -75.3 124.5 -9.7 -6.8 40.5 23 35 V I H 3> S+ 0 0 0 15,-3.1 4,-2.5 -2,-0.4 16,-0.1 0.739 98.4 63.4 -55.6 -27.8 -9.1 -9.7 43.0 24 36 V F H 34 S+ 0 0 68 14,-0.5 -1,-0.3 2,-0.2 6,-0.1 0.918 100.1 50.8 -66.4 -41.3 -12.1 -11.5 41.9 25 37 V Q H <4 S+ 0 0 132 -3,-0.9 -2,-0.2 1,-0.2 -1,-0.2 0.930 113.7 46.0 -60.3 -42.7 -10.8 -12.0 38.4 26 38 V E H < S+ 0 0 64 -4,-1.3 -2,-0.2 1,-0.3 -1,-0.2 0.885 129.0 25.3 -66.3 -41.8 -7.5 -13.4 39.9 27 39 V Y >< + 0 0 66 -4,-2.5 3,-1.0 1,-0.1 -1,-0.3 -0.631 66.9 163.5-123.6 72.9 -9.4 -15.7 42.3 28 40 V P T 3 S+ 0 0 78 0, 0.0 3,-0.2 0, 0.0 -3,-0.1 0.196 70.7 70.2 -78.0 24.7 -12.8 -16.3 40.7 29 41 V D T 3 S+ 0 0 137 1,-0.1 2,-1.2 -5,-0.1 3,-0.2 0.704 80.8 64.7-108.3 -33.4 -13.0 -19.2 43.2 30 42 V E X + 0 0 50 -3,-1.0 3,-1.2 1,-0.2 -1,-0.1 -0.429 55.2 141.7 -92.4 61.8 -13.5 -17.5 46.5 31 43 V I T 3 + 0 0 104 -2,-1.2 -1,-0.2 1,-0.3 -7,-0.0 0.445 63.7 70.6 -79.4 -0.5 -16.9 -16.0 45.7 32 44 V E T 3 S+ 0 0 95 -3,-0.2 2,-0.3 40,-0.0 -1,-0.3 0.439 93.9 71.0 -91.4 -4.9 -17.9 -16.7 49.3 33 45 V Y < - 0 0 47 -3,-1.2 2,-0.5 39,-0.1 39,-0.2 -0.766 69.0-147.2-111.2 158.5 -15.5 -14.0 50.4 34 46 V I E -F 71 0D 79 37,-1.5 37,-2.9 -2,-0.3 2,-0.2 -0.994 26.5-147.2-123.7 118.6 -15.6 -10.2 50.1 35 47 V F E -F 70 0D 15 -2,-0.5 35,-0.2 35,-0.2 3,-0.2 -0.534 3.6-128.3 -93.1 157.6 -12.2 -8.7 49.8 36 48 V K E S+F 69 0D 5 33,-1.6 33,-2.4 1,-0.4 2,-0.1 -0.897 103.0 24.3-149.6 112.4 -10.7 -5.4 51.0 37 49 V P S S- 0 0 0 0, 0.0 -1,-0.4 0, 0.0 32,-0.1 0.617 83.8-156.0 -75.4 169.1 -9.5 -4.0 49.0 38 50 V S S S+ 0 0 36 -3,-0.2 -15,-3.1 -2,-0.1 -14,-0.5 0.759 79.4 35.0 -77.6 -25.1 -11.4 -5.5 46.0 39 51 V b E S-E 22 0C 8 -17,-0.3 -17,-0.3 -16,-0.1 105,-0.2 -0.896 71.5-154.0-128.9 156.2 -8.6 -4.7 43.6 40 52 V V E -E 21 0C 0 -19,-3.3 -19,-2.7 -2,-0.3 2,-0.7 -0.897 24.3-107.6-131.7 159.9 -4.8 -4.6 43.8 41 53 V P E +E 20 0C 1 0, 0.0 2,-0.4 0, 0.0 -21,-0.2 -0.783 46.4 168.5 -88.2 112.0 -1.8 -2.8 42.1 42 54 V L E -E 19 0C 0 -23,-3.8 -23,-3.8 -2,-0.7 2,-0.6 -0.949 40.5-115.1-129.0 146.1 0.1 -5.2 39.9 43 55 V M E +E 18 0C 78 -2,-0.4 44,-3.1 -25,-0.2 2,-0.3 -0.681 49.3 167.6 -76.5 122.2 2.8 -4.8 37.2 44 56 V R E -E 17 0C 37 -27,-2.6 -27,-3.5 -2,-0.6 -29,-0.1 -0.974 42.4 -97.5-137.9 151.9 1.2 -6.0 34.0 45 57 V c E +E 16 0C 24 -2,-0.3 2,-0.3 -29,-0.3 -31,-0.1 -0.464 57.8 152.7 -65.6 138.7 2.0 -5.9 30.3 46 58 V G E +E 15 0C 19 -31,-1.6 -31,-2.5 -33,-0.1 2,-0.1 -0.952 16.7 67.7-158.5 169.1 0.2 -3.0 28.8 47 59 V G S S- 0 0 26 -2,-0.3 9,-0.3 69,-0.3 2,-0.2 -0.413 74.6 -59.7 105.2 178.0 0.5 -0.6 25.9 48 60 V d B -d 13 0B 10 -36,-1.6 -34,-2.4 -2,-0.1 7,-0.1 -0.674 15.3-161.1-105.6 158.4 0.3 -0.9 22.2 49 61 V e - 0 0 13 -2,-0.2 -1,-0.1 5,-0.2 6,-0.1 0.506 37.2-136.9-104.8 -13.8 2.3 -2.9 19.6 50 62 V N S S+ 0 0 12 4,-0.1 2,-0.3 1,-0.1 5,-0.1 0.747 77.0 87.2 62.6 27.5 1.0 -0.6 16.8 51 63 V D S > S- 0 0 16 3,-0.2 3,-3.6 521,-0.1 -1,-0.1 -0.790 73.0-141.3-159.2 105.7 0.4 -3.6 14.5 52 64 V E T 3 S+ 0 0 135 1,-0.3 43,-0.1 -2,-0.3 -2,-0.0 0.664 103.3 59.3 -40.2 -22.6 -2.8 -5.6 14.5 53 65 V G T 3 S+ 0 0 26 41,-0.1 42,-2.9 -4,-0.1 -1,-0.3 0.725 100.0 68.6 -83.7 -21.0 -0.8 -8.7 14.0 54 66 V L E < - G 0 94D 11 -3,-3.6 2,-0.4 40,-0.3 -5,-0.2 -0.669 60.6-167.6 -99.8 153.8 1.1 -8.2 17.2 55 67 V E E - G 0 93D 81 38,-3.1 38,-3.1 -2,-0.3 2,-0.7 -0.988 28.0-116.4-138.4 143.3 0.0 -8.3 20.8 56 68 V a E + G 0 92D 31 -2,-0.4 36,-0.2 -9,-0.3 -41,-0.1 -0.746 47.5 165.4 -82.7 112.3 1.8 -7.2 23.9 57 69 V V E - G 0 91D 38 34,-2.8 34,-3.0 -2,-0.7 2,-0.3 -0.892 39.3 -96.3-130.0 160.0 2.5 -10.2 26.1 58 70 V P E + G 0 90D 39 0, 0.0 32,-0.3 0, 0.0 3,-0.1 -0.559 27.7 178.3 -77.1 133.1 4.7 -11.1 29.1 59 71 V T E S+ 0 0 52 30,-3.6 2,-0.3 1,-0.3 31,-0.2 0.345 75.7 31.4-113.9 2.1 8.0 -12.8 28.5 60 72 V E E S- G 0 89D 83 29,-1.0 28,-2.0 2,-0.0 29,-1.4 -0.937 71.3-178.1-158.4 132.3 9.1 -13.0 32.1 61 73 V E E + G 0 87D 103 -2,-0.3 2,-0.3 26,-0.2 26,-0.2 -0.749 9.5 171.7-129.6 178.6 6.9 -13.3 35.3 62 74 V S E - 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