==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=4-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 15-AUG-07 2QYL . COMPND 2 MOLECULE: PHOSPHODIESTERASE 4B, CAMP-SPECIFIC; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR H.KE . 335 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 15522.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 245 73.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 11 3.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 48 14.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 172 51.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 10 3.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 2 2 1 0 0 0 2 0 5 0 1 3 0 0 0 0 0 0 0 1 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 151 A M > 0 0 145 0, 0.0 4,-1.9 0, 0.0 5,-0.2 0.000 360.0 360.0 360.0 144.6 72.6 19.1 7.9 2 152 A S H >> + 0 0 4 1,-0.2 4,-3.7 2,-0.2 5,-0.6 0.926 360.0 45.5 -53.4 -55.0 69.9 21.6 6.7 3 153 A I H >5S+ 0 0 54 1,-0.2 4,-2.3 2,-0.2 -1,-0.2 0.923 114.7 46.1 -58.9 -48.2 68.9 19.8 3.6 4 154 A S H 45S+ 0 0 80 1,-0.2 -1,-0.2 2,-0.2 -2,-0.2 0.818 121.5 41.0 -64.3 -30.1 68.6 16.3 5.2 5 155 A R H <5S+ 0 0 139 -4,-1.9 -2,-0.2 3,-0.1 -1,-0.2 0.887 135.6 10.5 -86.0 -43.5 66.8 17.9 8.1 6 156 A F H <5S- 0 0 8 -4,-3.7 42,-0.3 2,-0.3 41,-0.2 0.495 90.0-118.8-117.7 -8.2 64.4 20.4 6.4 7 157 A G S < + 0 0 45 24,-0.4 4,-2.2 1,-0.1 -1,-0.2 -0.406 60.9 145.1-121.3 54.3 67.9 30.2 10.0 13 163 A E H > S+ 0 0 64 -3,-0.4 4,-2.3 1,-0.2 5,-0.2 0.931 72.2 48.7 -56.1 -53.8 68.1 26.5 11.0 14 164 A D H > S+ 0 0 139 1,-0.2 4,-1.2 2,-0.2 -1,-0.2 0.853 115.1 45.4 -56.8 -39.4 67.4 27.0 14.7 15 165 A H H > S+ 0 0 101 2,-0.2 4,-1.8 1,-0.2 -1,-0.2 0.845 110.8 52.1 -76.0 -33.8 64.4 29.3 14.0 16 166 A L H X S+ 0 0 0 -4,-2.2 4,-2.2 20,-0.2 -2,-0.2 0.885 108.1 52.6 -68.6 -37.5 62.9 27.0 11.3 17 167 A A H < S+ 0 0 22 -4,-2.3 4,-0.3 2,-0.2 -1,-0.2 0.843 107.0 52.6 -66.6 -34.6 63.1 24.1 13.7 18 168 A K H >< S+ 0 0 119 -4,-1.2 3,-1.3 -5,-0.2 4,-0.3 0.927 110.4 46.9 -67.7 -44.7 61.2 26.0 16.4 19 169 A E H >< S+ 0 0 30 -4,-1.8 3,-1.9 1,-0.3 -2,-0.2 0.912 106.7 59.4 -62.2 -41.0 58.4 26.9 14.0 20 170 A L G >< S+ 0 0 27 -4,-2.2 3,-1.5 1,-0.3 -1,-0.3 0.539 82.3 81.8 -67.5 -5.6 58.3 23.2 12.8 21 171 A E G < S+ 0 0 119 -3,-1.3 3,-0.3 -4,-0.3 -1,-0.3 0.736 90.7 54.5 -69.3 -20.0 57.5 22.1 16.4 22 172 A D G X S+ 0 0 43 -3,-1.9 3,-2.5 -4,-0.3 6,-0.4 0.173 70.8 119.3 -96.9 16.3 53.9 23.1 15.5 23 173 A L T < S+ 0 0 11 -3,-1.5 -1,-0.2 1,-0.3 -2,-0.1 0.833 80.7 41.6 -48.9 -40.3 53.9 20.8 12.4 24 174 A N T 3 S+ 0 0 80 -3,-0.3 2,-0.4 -4,-0.2 -1,-0.3 0.267 102.8 95.1 -93.2 10.8 51.0 18.8 13.8 25 175 A K S X S- 0 0 109 -3,-2.5 3,-1.5 1,-0.1 73,-0.1 -0.829 71.5-139.9-109.8 144.6 49.2 21.9 15.2 26 176 A W T 3 S+ 0 0 37 -2,-0.4 -1,-0.1 1,-0.3 -4,-0.0 0.771 103.7 63.7 -65.4 -24.8 46.4 24.0 13.6 27 177 A G T 3 + 0 0 57 221,-0.1 -1,-0.3 2,-0.1 -4,-0.1 0.292 69.5 131.8 -86.4 11.6 48.3 27.0 15.1 28 178 A L < - 0 0 4 -3,-1.5 2,-0.8 -6,-0.4 -8,-0.1 -0.347 55.6-133.9 -62.1 143.0 51.4 26.6 13.0 29 179 A N > - 0 0 20 -10,-0.2 4,-1.4 1,-0.2 3,-0.3 -0.861 22.2-177.5-104.1 102.7 52.5 29.9 11.4 30 180 A I H > S+ 0 0 4 -2,-0.8 4,-2.4 1,-0.2 -1,-0.2 0.765 79.8 65.5 -70.5 -25.9 53.4 29.2 7.8 31 181 A F H > S+ 0 0 23 1,-0.2 4,-2.0 2,-0.2 -1,-0.2 0.911 105.0 45.2 -61.6 -41.5 54.4 32.8 7.2 32 182 A N H > S+ 0 0 59 -3,-0.3 4,-1.8 2,-0.2 -1,-0.2 0.855 107.8 56.6 -70.1 -36.9 57.3 32.3 9.6 33 183 A V H < S+ 0 0 0 -4,-1.4 3,-0.4 1,-0.2 4,-0.3 0.941 109.1 48.0 -59.0 -43.7 58.2 28.9 8.0 34 184 A A H ><>S+ 0 0 8 -4,-2.4 5,-2.9 1,-0.2 3,-1.2 0.923 110.0 52.3 -61.2 -44.4 58.5 30.9 4.8 35 185 A G H 3<5S+ 0 0 50 -4,-2.0 3,-0.3 1,-0.2 -1,-0.2 0.746 114.2 41.3 -65.2 -25.9 60.6 33.5 6.5 36 186 A Y T 3<5S+ 0 0 68 -4,-1.8 -24,-0.4 -3,-0.4 -1,-0.2 0.266 111.5 56.6-104.9 10.3 63.1 31.0 7.9 37 187 A S T < 5S- 0 0 1 -3,-1.2 -2,-0.2 -4,-0.3 -1,-0.2 0.094 116.8-101.6-126.1 20.9 63.3 28.8 4.8 38 188 A H T 5S- 0 0 95 -3,-0.3 -3,-0.2 1,-0.2 -4,-0.1 0.876 82.8 -55.6 58.8 37.5 64.4 31.4 2.3 39 189 A N S + 0 0 63 -6,-0.4 4,-2.6 -7,-0.3 5,-0.3 -0.411 19.8 148.4-127.9 52.8 60.5 27.8 0.4 41 191 A P H > S+ 0 0 0 0, 0.0 4,-2.4 0, 0.0 5,-0.2 0.852 70.7 48.6 -57.6 -38.0 57.4 27.1 2.6 42 192 A L H > S+ 0 0 0 2,-0.2 4,-2.5 3,-0.2 5,-0.3 0.951 114.3 42.5 -71.3 -49.6 56.0 24.4 0.3 43 193 A T H > S+ 0 0 0 2,-0.2 4,-2.2 1,-0.2 5,-0.2 0.952 118.6 47.2 -61.1 -47.8 59.2 22.4 -0.1 44 194 A C H X S+ 0 0 0 -4,-2.6 4,-2.3 1,-0.2 -2,-0.2 0.944 115.1 43.5 -59.9 -51.4 60.0 22.8 3.6 45 195 A I H X S+ 0 0 0 -4,-2.4 4,-2.5 -5,-0.3 -1,-0.2 0.868 113.9 50.4 -65.7 -35.9 56.5 21.9 4.9 46 196 A M H X S+ 0 0 0 -4,-2.5 4,-2.4 -5,-0.2 -1,-0.2 0.895 111.4 48.7 -69.6 -37.4 56.1 18.9 2.5 47 197 A Y H X S+ 0 0 5 -4,-2.2 4,-2.2 -5,-0.3 5,-0.2 0.925 112.9 48.0 -65.6 -44.5 59.5 17.5 3.5 48 198 A A H X S+ 0 0 14 -4,-2.3 4,-2.8 -42,-0.3 -2,-0.2 0.929 112.5 48.5 -62.0 -46.4 58.6 17.9 7.2 49 199 A I H X S+ 0 0 0 -4,-2.5 4,-2.4 1,-0.2 6,-0.2 0.923 112.1 48.5 -59.9 -47.0 55.2 16.2 6.8 50 200 A F H X>S+ 0 0 1 -4,-2.4 5,-1.9 2,-0.2 4,-0.7 0.880 113.5 46.6 -63.8 -37.9 56.7 13.3 4.8 51 201 A Q H ><5S+ 0 0 73 -4,-2.2 3,-0.8 3,-0.2 -2,-0.2 0.941 111.5 52.6 -67.0 -46.3 59.4 12.7 7.4 52 202 A E H 3<5S+ 0 0 105 -4,-2.8 -2,-0.2 1,-0.3 -1,-0.2 0.892 117.9 36.2 -54.9 -44.2 56.8 13.0 10.2 53 203 A R H 3<5S- 0 0 58 -4,-2.4 -1,-0.3 -5,-0.2 -2,-0.2 0.471 105.8-126.4 -90.2 -3.0 54.6 10.4 8.6 54 204 A D T < + 0 0 3 -5,-1.9 4,-2.6 -6,-0.2 6,-0.2 0.840 60.8 60.3 -68.3 -34.7 56.1 8.4 3.8 56 206 A L H 4>S+ 0 0 12 -6,-0.5 5,-2.8 2,-0.2 -1,-0.2 0.938 112.0 39.5 -59.2 -47.2 59.5 8.5 2.0 57 207 A K H >45S+ 0 0 157 3,-0.2 3,-1.6 2,-0.2 -2,-0.2 0.963 114.8 52.5 -66.1 -52.3 60.4 5.1 3.5 58 208 A T H 3<5S+ 0 0 78 -4,-2.2 -2,-0.2 1,-0.3 -1,-0.2 0.878 120.3 33.1 -52.1 -44.2 56.9 3.6 3.1 59 209 A F T 3<5S- 0 0 14 -4,-2.6 116,-0.3 -5,-0.1 -1,-0.3 0.175 109.0-116.6-102.3 18.0 56.7 4.4 -0.6 60 210 A R T < 5 + 0 0 160 -3,-1.6 2,-0.6 1,-0.2 115,-0.2 0.897 57.9 157.0 49.3 49.6 60.4 4.1 -1.4 61 211 A I < - 0 0 10 -5,-2.8 -1,-0.2 -6,-0.2 -2,-0.1 -0.926 39.1-131.8-104.9 119.6 60.8 7.7 -2.4 62 212 A S > - 0 0 59 -2,-0.6 4,-2.3 1,-0.1 5,-0.2 -0.435 13.9-126.0 -71.6 146.4 64.4 8.9 -2.1 63 213 A S H > S+ 0 0 48 1,-0.2 4,-2.7 2,-0.2 5,-0.2 0.871 110.6 53.8 -57.4 -38.7 64.9 12.2 -0.3 64 214 A D H > S+ 0 0 119 2,-0.2 4,-2.6 1,-0.2 -1,-0.2 0.940 108.9 45.7 -63.3 -49.6 66.7 13.6 -3.3 65 215 A T H > S+ 0 0 34 1,-0.2 4,-2.5 2,-0.2 -2,-0.2 0.905 115.0 49.3 -60.4 -42.8 64.0 12.8 -5.8 66 216 A F H X S+ 0 0 1 -4,-2.3 4,-3.2 2,-0.2 5,-0.2 0.931 112.3 45.8 -63.4 -48.8 61.4 14.3 -3.4 67 217 A I H X S+ 0 0 13 -4,-2.7 4,-2.7 1,-0.2 5,-0.3 0.907 113.0 51.9 -62.1 -40.3 63.3 17.5 -2.7 68 218 A T H X S+ 0 0 54 -4,-2.6 4,-1.7 -5,-0.2 -2,-0.2 0.925 113.7 43.4 -63.1 -43.7 63.9 17.8 -6.4 69 219 A Y H X S+ 0 0 0 -4,-2.5 4,-3.1 100,-0.2 -2,-0.2 0.959 114.5 49.0 -66.2 -51.0 60.2 17.4 -7.2 70 220 A M H X S+ 0 0 1 -4,-3.2 4,-2.8 1,-0.2 5,-0.2 0.909 110.7 49.9 -56.4 -45.1 59.1 19.7 -4.4 71 221 A M H X S+ 0 0 58 -4,-2.7 4,-1.9 -5,-0.2 -1,-0.2 0.907 113.8 46.5 -60.5 -41.5 61.5 22.5 -5.3 72 222 A T H X S+ 0 0 29 -4,-1.7 4,-0.9 -5,-0.3 -2,-0.2 0.928 111.7 50.4 -65.9 -46.4 60.3 22.3 -9.0 73 223 A L H >< S+ 0 0 0 -4,-3.1 3,-1.4 1,-0.2 -2,-0.2 0.948 111.6 48.4 -55.6 -50.5 56.7 22.2 -8.0 74 224 A E H >< S+ 0 0 10 -4,-2.8 3,-1.8 1,-0.3 -1,-0.2 0.866 104.5 59.3 -59.6 -38.2 57.1 25.3 -5.8 75 225 A D H 3< S+ 0 0 98 -4,-1.9 -1,-0.3 1,-0.3 -2,-0.2 0.718 99.9 60.2 -63.8 -19.6 59.0 27.1 -8.6 76 226 A H T << S+ 0 0 74 -3,-1.4 51,-0.8 -4,-0.9 2,-0.4 0.431 84.2 90.4 -91.4 1.4 55.8 26.6 -10.7 77 227 A Y S < S- 0 0 12 -3,-1.8 2,-0.3 49,-0.2 8,-0.1 -0.780 89.3-109.0 -91.7 141.0 53.7 28.6 -8.3 78 228 A H - 0 0 62 6,-0.5 3,-0.5 50,-0.4 8,-0.2 -0.548 24.7-168.6 -74.1 131.5 53.6 32.3 -9.1 79 229 A S S S+ 0 0 113 -2,-0.3 -1,-0.2 1,-0.2 6,-0.1 0.535 88.0 63.4 -92.9 -9.1 55.4 34.6 -6.7 80 230 A D S S+ 0 0 108 -3,-0.0 2,-0.5 49,-0.0 -1,-0.2 0.169 84.3 91.0 -98.5 16.8 53.8 37.6 -8.3 81 231 A V S S- 0 0 6 -3,-0.5 49,-0.1 1,-0.1 4,-0.1 -0.959 72.4-144.1-112.2 128.0 50.3 36.4 -7.3 82 232 A A S S+ 0 0 12 -2,-0.5 178,-0.2 177,-0.1 3,-0.1 0.854 86.8 5.3 -61.6 -43.1 49.2 37.8 -3.9 83 233 A Y S >S+ 0 0 15 176,-0.3 2,-2.4 177,-0.1 5,-0.5 0.805 119.2 62.7-110.6 -54.5 47.3 34.8 -2.5 84 234 A H T 5S+ 0 0 29 175,-0.1 -6,-0.5 4,-0.1 44,-0.3 -0.193 79.7 113.0 -75.6 52.6 47.6 31.8 -4.8 85 235 A N T >>5S- 0 0 19 -2,-2.4 4,-1.3 -3,-0.1 3,-1.0 -0.446 90.0 -77.4-108.1-175.5 51.3 31.4 -4.4 86 236 A S H 3>5S+ 0 0 15 1,-0.2 4,-2.6 -12,-0.2 5,-0.2 0.686 124.6 66.9 -61.6 -19.7 53.3 28.6 -2.8 87 237 A L H 3>5S+ 0 0 6 2,-0.2 4,-2.3 1,-0.2 -1,-0.2 0.907 102.1 47.2 -67.1 -41.1 52.5 29.9 0.7 88 238 A H H <>< S+ 0 0 24 -4,-1.8 3,-0.8 1,-0.2 -2,-0.2 0.917 112.2 52.0 -71.8 -42.1 46.5 18.1 10.7 99 249 A L H >< S+ 0 0 3 -4,-2.7 3,-1.7 1,-0.2 -2,-0.2 0.858 103.4 57.9 -61.4 -37.4 43.0 17.2 9.5 100 250 A L H 3< S+ 0 0 12 -4,-2.6 -1,-0.2 1,-0.3 9,-0.2 0.772 103.3 55.7 -65.0 -23.5 44.1 13.6 8.6 101 251 A S T << S+ 0 0 65 -3,-0.8 -1,-0.3 -4,-0.6 -2,-0.2 0.286 73.4 137.6 -92.7 10.3 45.2 13.2 12.2 102 252 A T X - 0 0 15 -3,-1.7 3,-2.7 1,-0.1 4,-0.2 -0.381 61.3-127.9 -59.1 125.2 41.8 14.1 13.7 103 253 A P G > S+ 0 0 85 0, 0.0 3,-1.6 0, 0.0 -1,-0.1 0.830 107.3 59.6 -43.1 -41.2 41.3 11.6 16.5 104 254 A A G 3 S+ 0 0 10 1,-0.3 118,-2.5 208,-0.3 -2,-0.1 0.691 106.7 46.8 -64.9 -20.0 37.9 10.6 15.1 105 255 A L G X> S+ 0 0 3 -3,-2.7 3,-2.0 116,-0.2 4,-0.6 0.170 80.5 147.5-108.0 18.0 39.5 9.5 11.8 106 256 A D T <4 S- 0 0 109 -3,-1.6 -5,-0.1 1,-0.3 -6,-0.0 -0.293 77.5 -5.7 -58.5 131.5 42.3 7.5 13.5 107 257 A A T 34 S+ 0 0 96 1,-0.1 -1,-0.3 2,-0.1 -2,-0.0 0.600 103.3 115.3 59.2 13.3 43.3 4.4 11.4 108 258 A V T <4 + 0 0 21 -3,-2.0 2,-0.2 2,-0.1 -2,-0.1 0.929 63.0 57.5 -76.5 -46.2 40.5 5.2 9.0 109 259 A F S < S- 0 0 21 -4,-0.6 -2,-0.1 -9,-0.2 2,-0.1 -0.584 80.8-121.2 -92.7 149.1 42.6 6.0 5.9 110 260 A T > - 0 0 64 -2,-0.2 4,-2.1 1,-0.1 5,-0.1 -0.345 30.6-110.9 -76.3 164.4 45.2 3.9 4.1 111 261 A D H > S+ 0 0 98 1,-0.2 4,-2.8 2,-0.2 5,-0.2 0.868 120.2 53.9 -65.9 -33.6 48.7 5.2 3.7 112 262 A L H > S+ 0 0 23 2,-0.2 4,-2.8 1,-0.2 -1,-0.2 0.881 107.5 50.0 -67.6 -37.3 48.1 5.6 -0.0 113 263 A E H > S+ 0 0 6 2,-0.2 4,-2.4 1,-0.2 -2,-0.2 0.903 111.4 49.6 -66.9 -39.4 45.0 7.7 0.7 114 264 A I H X S+ 0 0 23 -4,-2.1 4,-2.2 2,-0.2 5,-0.3 0.939 111.6 48.1 -62.8 -49.1 47.1 9.8 3.1 115 265 A L H X S+ 0 0 0 -4,-2.8 4,-2.6 1,-0.2 5,-0.2 0.944 112.5 49.5 -56.2 -49.1 49.9 10.2 0.5 116 266 A A H X S+ 0 0 0 -4,-2.8 4,-2.9 1,-0.2 -1,-0.2 0.892 110.0 50.5 -59.2 -42.8 47.3 11.2 -2.1 117 267 A A H X S+ 0 0 0 -4,-2.4 4,-2.1 2,-0.2 -1,-0.2 0.926 114.1 42.5 -63.6 -46.7 45.6 13.8 0.1 118 268 A I H X S+ 0 0 0 -4,-2.2 4,-2.1 2,-0.2 -2,-0.2 0.902 116.1 49.1 -68.7 -39.4 48.8 15.6 1.1 119 269 A F H X S+ 0 0 1 -4,-2.6 4,-2.1 -5,-0.3 5,-0.3 0.943 109.8 52.2 -63.6 -47.2 50.1 15.4 -2.5 120 270 A A H X S+ 0 0 0 -4,-2.9 4,-2.1 -5,-0.2 -2,-0.2 0.917 108.7 51.2 -54.3 -46.2 46.8 16.8 -3.8 121 271 A A H < S+ 0 0 0 -4,-2.1 4,-0.3 1,-0.2 -28,-0.3 0.930 108.5 51.6 -58.1 -46.1 47.1 19.7 -1.4 122 272 A A H < S+ 0 0 0 -4,-2.1 3,-0.3 1,-0.2 -1,-0.2 0.892 121.3 30.8 -60.7 -41.4 50.6 20.5 -2.5 123 273 A I H >< S+ 0 0 0 -4,-2.1 3,-2.1 1,-0.2 -1,-0.2 0.597 87.6 105.9 -94.3 -9.2 49.7 20.6 -6.2 124 274 A H T 3< S+ 0 0 0 -4,-2.1 33,-0.2 1,-0.3 -1,-0.2 0.622 94.4 23.2 -48.4 -22.8 46.1 21.8 -6.0 125 275 A D T > S+ 0 0 7 -3,-0.3 3,-1.5 -4,-0.3 -1,-0.3 0.202 83.1 153.2-128.9 16.3 46.9 25.4 -7.1 126 276 A V T < S+ 0 0 0 -3,-2.1 -49,-0.2 1,-0.3 34,-0.2 -0.165 72.9 6.6 -55.3 137.5 50.1 25.1 -9.1 127 277 A D T 3 S+ 0 0 53 -51,-0.8 -1,-0.3 1,-0.2 -50,-0.2 0.747 83.5 172.5 61.2 28.5 50.6 27.7 -11.8 128 278 A H < - 0 0 15 -3,-1.5 -50,-0.4 -44,-0.3 -1,-0.2 -0.524 24.6-152.3 -67.4 124.6 47.5 29.6 -10.7 129 279 A P - 0 0 51 0, 0.0 -1,-0.1 0, 0.0 3,-0.1 0.673 38.3-108.0 -74.7 -18.2 47.5 32.9 -12.7 130 280 A G S S+ 0 0 3 1,-0.4 2,-0.3 -49,-0.1 137,-0.3 0.554 88.0 97.6 102.4 6.9 45.6 35.0 -10.1 131 281 A V S S- 0 0 7 135,-0.1 -1,-0.4 136,-0.1 133,-0.1 -0.910 73.5-106.4-125.8 154.5 42.3 35.2 -12.0 132 282 A S > - 0 0 46 -2,-0.3 4,-1.8 -3,-0.1 5,-0.2 -0.229 27.7-107.9 -77.6 168.0 39.2 33.1 -11.6 133 283 A N H > S+ 0 0 31 1,-0.2 4,-2.6 2,-0.2 5,-0.2 0.888 121.0 56.1 -60.5 -39.5 37.8 30.3 -13.9 134 284 A Q H > S+ 0 0 102 1,-0.2 4,-3.6 2,-0.2 -1,-0.2 0.870 104.8 51.6 -62.8 -37.3 35.1 32.7 -14.9 135 285 A F H > S+ 0 0 8 2,-0.2 4,-1.6 1,-0.2 -1,-0.2 0.895 111.2 47.7 -65.7 -39.0 37.6 35.3 -16.0 136 286 A L H <>S+ 0 0 15 -4,-1.8 5,-3.0 2,-0.2 -2,-0.2 0.894 116.0 45.2 -67.3 -38.7 39.3 32.6 -18.1 137 287 A I H ><5S+ 0 0 34 -4,-2.6 3,-1.7 3,-0.2 -2,-0.2 0.931 112.0 50.5 -68.8 -48.1 35.9 31.6 -19.5 138 288 A N H 3<5S+ 0 0 79 -4,-3.6 -1,-0.2 1,-0.3 -2,-0.2 0.772 111.2 48.8 -63.5 -27.2 34.8 35.2 -20.2 139 289 A T T 3<5S- 0 0 41 -4,-1.6 -1,-0.3 -5,-0.2 -2,-0.2 0.234 114.6-116.1 -96.8 13.4 38.1 36.0 -22.0 140 290 A N T < 5 - 0 0 133 -3,-1.7 -3,-0.2 1,-0.1 -2,-0.1 0.883 42.5-164.6 54.9 46.7 37.8 32.8 -24.2 141 291 A S >< - 0 0 22 -5,-3.0 4,-1.9 1,-0.1 5,-0.2 -0.210 27.3-132.0 -59.8 148.0 40.9 31.2 -22.8 142 292 A E H > S+ 0 0 160 1,-0.2 4,-2.4 2,-0.2 -1,-0.1 0.860 111.8 57.1 -68.4 -32.2 42.4 28.3 -24.7 143 293 A L H > S+ 0 0 34 2,-0.2 4,-1.6 1,-0.2 -1,-0.2 0.914 104.8 50.1 -62.9 -44.3 42.6 26.6 -21.3 144 294 A A H 4>S+ 0 0 2 -8,-0.2 5,-2.9 2,-0.2 6,-0.3 0.932 111.5 46.6 -61.0 -49.7 38.8 27.1 -20.8 145 295 A L H ><5S+ 0 0 140 -4,-1.9 3,-2.1 1,-0.2 -1,-0.2 0.942 108.5 58.2 -57.2 -47.1 38.0 25.6 -24.2 146 296 A M H 3<5S+ 0 0 107 -4,-2.4 -1,-0.2 1,-0.3 -2,-0.2 0.841 114.3 35.4 -51.9 -40.5 40.4 22.7 -23.5 147 297 A Y T ><5S- 0 0 55 -4,-1.6 3,-2.5 -3,-0.3 -1,-0.3 0.091 112.4-114.6-104.4 22.6 38.5 21.7 -20.3 148 298 A N T < 5 - 0 0 141 -3,-2.1 -3,-0.2 1,-0.3 -2,-0.1 0.841 65.9 -67.9 47.5 41.2 35.0 22.6 -21.7 149 299 A D T 3 S+ 0 0 8 -2,-0.6 4,-2.6 3,-0.1 5,-0.3 0.926 81.7 174.4 46.4 52.4 37.1 23.1 -13.4 152 302 A V H > S+ 0 0 1 -3,-0.3 4,-1.3 1,-0.2 5,-0.1 0.958 72.7 32.1 -53.8 -63.2 39.4 24.9 -15.8 153 303 A L H > S+ 0 0 3 1,-0.2 4,-3.3 2,-0.2 5,-0.2 0.880 117.1 57.3 -65.2 -37.8 42.2 25.8 -13.4 154 304 A E H > S+ 0 0 15 1,-0.3 4,-2.0 2,-0.2 -1,-0.2 0.900 107.7 47.4 -60.7 -41.2 41.7 22.7 -11.3 155 305 A N H X S+ 0 0 45 -4,-2.6 4,-2.0 1,-0.2 -1,-0.3 0.815 113.1 51.0 -68.2 -29.5 42.3 20.5 -14.4 156 306 A H H X S+ 0 0 31 -4,-1.3 4,-2.6 -5,-0.3 5,-0.3 0.920 106.4 51.6 -73.6 -44.1 45.3 22.7 -15.2 157 307 A H H X S+ 0 0 0 -4,-3.3 4,-3.1 1,-0.2 5,-0.2 0.923 112.2 49.0 -57.8 -41.4 46.8 22.4 -11.7 158 308 A L H X S+ 0 0 7 -4,-2.0 4,-2.5 -5,-0.2 5,-0.3 0.919 109.4 50.6 -63.1 -45.6 46.4 18.6 -12.1 159 309 A A H X S+ 0 0 43 -4,-2.0 4,-2.4 2,-0.2 -2,-0.2 0.915 116.2 42.0 -60.0 -43.9 48.0 18.6 -15.5 160 310 A V H X S+ 0 0 20 -4,-2.6 4,-2.4 2,-0.2 -2,-0.2 0.947 112.0 53.0 -69.7 -49.2 51.0 20.5 -14.2 161 311 A G H X S+ 0 0 0 -4,-3.1 4,-0.5 -5,-0.3 -2,-0.2 0.919 116.7 39.4 -52.3 -46.9 51.4 18.7 -11.0 162 312 A F H >< S+ 0 0 12 -4,-2.5 3,-1.3 -5,-0.2 4,-0.4 0.922 111.9 55.4 -71.4 -44.2 51.5 15.3 -12.8 163 313 A K H >< S+ 0 0 132 -4,-2.4 3,-2.4 -5,-0.3 4,-0.3 0.869 97.4 63.7 -58.1 -38.4 53.6 16.5 -15.8 164 314 A L H >< S+ 0 0 8 -4,-2.4 3,-2.1 1,-0.3 -1,-0.3 0.800 88.5 70.8 -57.5 -26.9 56.4 17.7 -13.5 165 315 A L T << S+ 0 0 14 -3,-1.3 5,-0.3 -4,-0.5 -1,-0.3 0.746 90.9 61.0 -60.1 -23.3 56.9 14.1 -12.3 166 316 A Q T < S+ 0 0 160 -3,-2.4 -1,-0.3 -4,-0.4 -2,-0.2 0.562 84.0 106.9 -81.6 -8.4 58.3 13.5 -15.8 167 317 A E S X S- 0 0 93 -3,-2.1 3,-2.3 -4,-0.3 4,-0.4 -0.259 91.6 -65.6 -68.9 159.3 61.1 16.0 -15.2 168 318 A E T 3 S- 0 0 146 1,-0.3 -1,-0.2 2,-0.1 -2,-0.1 -0.198 117.6 -13.8 -48.7 117.8 64.7 14.9 -14.6 169 319 A H T 3 S+ 0 0 127 -3,-0.1 -1,-0.3 1,-0.1 -100,-0.2 0.809 108.3 112.9 56.0 32.4 64.9 12.9 -11.3 170 320 A C < + 0 0 3 -3,-2.3 2,-1.7 -5,-0.3 -2,-0.1 0.480 31.2 111.3-111.0 -5.0 61.4 14.2 -10.3 171 321 A D > + 0 0 42 -4,-0.4 3,-1.4 1,-0.2 4,-0.2 -0.511 34.1 171.2 -76.6 88.5 59.3 11.0 -10.4 172 322 A I T 3 S+ 0 0 4 -2,-1.7 3,-0.2 1,-0.3 -1,-0.2 0.570 77.4 53.7 -72.6 -8.9 58.5 10.5 -6.7 173 323 A F T > S+ 0 0 4 1,-0.1 3,-1.7 -3,-0.1 -1,-0.3 0.187 72.0 115.1-109.2 15.0 56.1 7.7 -7.5 174 324 A M T < S+ 0 0 122 -3,-1.4 -1,-0.1 1,-0.3 -2,-0.1 0.836 77.5 46.8 -53.2 -38.0 58.6 5.7 -9.6 175 325 A N T 3 S+ 0 0 56 -116,-0.3 -1,-0.3 -115,-0.2 2,-0.1 0.432 86.4 104.4 -90.9 3.3 58.6 2.9 -7.1 176 326 A L S < S- 0 0 14 -3,-1.7 2,-0.1 1,-0.1 -3,-0.0 -0.450 78.0-107.7 -75.9 157.7 54.8 2.5 -6.7 177 327 A T > - 0 0 77 -2,-0.1 4,-2.7 1,-0.1 5,-0.2 -0.323 30.4-103.1 -78.8 168.9 53.2 -0.5 -8.5 178 328 A K H > S+ 0 0 166 1,-0.2 4,-2.1 2,-0.2 5,-0.2 0.901 125.3 49.3 -59.4 -38.7 51.0 0.0 -11.5 179 329 A K H > S+ 0 0 138 2,-0.2 4,-2.5 1,-0.2 -1,-0.2 0.914 110.6 47.6 -67.4 -44.5 48.0 -0.5 -9.3 180 330 A Q H > S+ 0 0 66 1,-0.2 4,-2.8 2,-0.2 -2,-0.2 0.899 112.7 50.2 -64.5 -39.0 49.1 1.9 -6.6 181 331 A R H X S+ 0 0 83 -4,-2.7 4,-2.6 2,-0.2 -1,-0.2 0.900 111.1 48.3 -66.4 -40.4 49.9 4.6 -9.2 182 332 A Q H X S+ 0 0 112 -4,-2.1 4,-2.0 -5,-0.2 -2,-0.2 0.934 114.1 46.6 -64.7 -45.5 46.5 4.1 -10.9 183 333 A T H X S+ 0 0 45 -4,-2.5 4,-2.1 1,-0.2 -2,-0.2 0.930 114.1 47.3 -62.3 -46.4 44.7 4.4 -7.5 184 334 A L H X S+ 0 0 5 -4,-2.8 4,-2.8 1,-0.2 5,-0.3 0.924 109.6 52.9 -62.1 -45.9 46.7 7.4 -6.5 185 335 A R H X S+ 0 0 127 -4,-2.6 4,-2.3 1,-0.2 -1,-0.2 0.911 111.0 46.8 -56.9 -45.8 46.2 9.2 -9.8 186 336 A K H X S+ 0 0 114 -4,-2.0 4,-2.0 2,-0.2 -1,-0.2 0.882 113.9 47.7 -64.7 -39.9 42.4 8.8 -9.5 187 337 A M H X S+ 0 0 1 -4,-2.1 4,-2.4 2,-0.2 -2,-0.2 0.906 112.8 47.8 -68.7 -41.1 42.3 9.9 -5.9 188 338 A V H X S+ 0 0 0 -4,-2.8 4,-2.7 2,-0.2 5,-0.3 0.912 111.0 51.1 -65.1 -44.0 44.4 13.0 -6.5 189 339 A I H X S+ 0 0 46 -4,-2.3 4,-2.5 -5,-0.3 5,-0.2 0.939 111.5 49.8 -57.3 -45.5 42.3 13.9 -9.5 190 340 A D H X S+ 0 0 25 -4,-2.0 4,-1.0 1,-0.2 -2,-0.2 0.890 113.2 44.6 -60.3 -43.8 39.2 13.6 -7.3 191 341 A M H < S+ 0 0 0 -4,-2.4 -1,-0.2 2,-0.2 -2,-0.2 0.877 114.3 46.8 -73.5 -37.0 40.6 15.7 -4.5 192 342 A V H >< S+ 0 0 0 -4,-2.7 3,-2.3 1,-0.2 4,-0.3 0.928 110.7 52.0 -70.5 -43.3 42.0 18.5 -6.7 193 343 A L H >< S+ 0 0 45 -4,-2.5 3,-1.5 -5,-0.3 -1,-0.2 0.830 101.6 65.1 -60.5 -26.8 38.8 18.7 -8.7 194 344 A A T 3< S+ 0 0 0 -4,-1.0 -1,-0.3 1,-0.3 -2,-0.2 0.545 89.3 65.2 -72.0 -8.4 37.1 19.0 -5.3 195 345 A T T < S+ 0 0 3 -3,-2.3 2,-0.7 -4,-0.1 -1,-0.3 0.504 70.5 113.1 -92.3 -3.2 38.8 22.3 -4.7 196 346 A D X - 0 0 5 -3,-1.5 3,-2.6 -4,-0.3 4,-0.2 -0.586 66.5-146.0 -68.1 109.4 36.8 23.8 -7.6 197 347 A M G > S+ 0 0 94 -2,-0.7 3,-1.5 1,-0.3 4,-0.2 0.735 93.5 67.2 -53.4 -26.3 34.7 26.3 -5.6 198 348 A S G 3 S+ 0 0 90 1,-0.3 -1,-0.3 2,-0.1 3,-0.3 0.669 95.7 57.7 -71.2 -13.1 31.7 25.8 -8.0 199 349 A K G <> S+ 0 0 51 -3,-2.6 4,-2.1 1,-0.2 3,-0.5 0.392 74.0 109.5 -94.0 1.5 31.5 22.2 -6.6 200 350 A H H <> S+ 0 0 17 -3,-1.5 4,-2.6 1,-0.2 5,-0.2 0.880 77.1 46.2 -42.7 -55.0 31.1 23.4 -3.1 201 351 A M H > S+ 0 0 113 -3,-0.3 4,-2.2 -4,-0.2 -1,-0.2 0.848 108.5 53.4 -63.1 -37.2 27.4 22.4 -2.7 202 352 A S H > S+ 0 0 57 -3,-0.5 4,-1.6 -4,-0.2 -1,-0.2 0.904 113.2 46.6 -65.4 -36.7 27.8 18.9 -4.2 203 353 A L H X S+ 0 0 0 -4,-2.1 4,-2.4 2,-0.2 -2,-0.2 0.937 111.9 47.7 -68.7 -49.1 30.5 18.3 -1.7 204 354 A L H X S+ 0 0 4 -4,-2.6 4,-2.3 1,-0.2 -2,-0.2 0.868 109.1 55.3 -61.6 -36.7 28.7 19.7 1.3 205 355 A A H X S+ 0 0 47 -4,-2.2 4,-1.8 2,-0.2 -1,-0.2 0.926 109.7 46.3 -61.8 -44.6 25.6 17.7 0.4 206 356 A D H X S+ 0 0 49 -4,-1.6 4,-1.8 1,-0.2 -2,-0.2 0.909 110.1 54.4 -63.9 -41.9 27.6 14.5 0.4 207 357 A L H X S+ 0 0 0 -4,-2.4 4,-1.7 1,-0.2 -1,-0.2 0.883 106.7 50.2 -60.4 -41.1 29.2 15.4 3.7 208 358 A K H X S+ 0 0 86 -4,-2.3 4,-3.1 1,-0.2 -1,-0.2 0.918 108.3 53.3 -64.1 -40.7 25.8 15.9 5.4 209 359 A T H X S+ 0 0 64 -4,-1.8 4,-2.2 1,-0.2 -1,-0.2 0.860 108.1 51.3 -59.4 -36.9 24.8 12.4 4.1 210 360 A M H < S+ 0 0 20 -4,-1.8 -1,-0.2 2,-0.2 -2,-0.2 0.824 111.1 47.5 -69.7 -33.8 28.0 11.1 5.7 211 361 A V H >< S+ 0 0 33 -4,-1.7 3,-1.6 2,-0.2 -2,-0.2 0.929 111.8 50.0 -72.2 -46.2 27.0 12.7 9.0 212 362 A E H 3< S+ 0 0 153 -4,-3.1 -2,-0.2 1,-0.3 -3,-0.2 0.901 116.8 39.9 -58.2 -44.6 23.5 11.4 8.8 213 363 A T T 3< S+ 0 0 82 -4,-2.2 -1,-0.3 -5,-0.2 -2,-0.2 0.080 90.3 153.0 -93.8 22.9 24.6 7.9 8.1 214 364 A K < - 0 0 65 -3,-1.6 2,-0.4 8,-0.0 -3,-0.1 -0.171 22.7-172.7 -55.4 141.6 27.5 8.2 10.6 215 365 A K - 0 0 143 8,-0.2 8,-2.6 0, 0.0 2,-0.3 -0.954 1.9-174.7-143.7 120.3 28.8 5.1 12.4 216 366 A V B -A 222 0A 76 -2,-0.4 6,-0.2 6,-0.2 5,-0.1 -0.743 16.7-128.6-114.9 163.5 31.3 5.0 15.2 217 367 A T - 0 0 48 4,-2.2 3,-0.1 -2,-0.3 -1,-0.1 -0.333 40.4 -89.5 -97.5-178.7 33.1 2.2 17.1 218 368 A S S S+ 0 0 133 1,-0.2 -1,-0.0 2,-0.1 -2,-0.0 0.946 129.9 51.1 -57.1 -50.0 33.4 1.6 20.8 219 369 A S S S- 0 0 94 1,-0.1 -1,-0.2 2,-0.1 -3,-0.0 0.825 122.3-110.1 -56.6 -33.8 36.6 3.8 21.0 220 370 A G S S+ 0 0 37 1,-0.4 2,-0.1 -3,-0.1 -2,-0.1 0.273 71.3 138.5 118.8 -7.4 34.6 6.5 19.1 221 371 A V - 0 0 27 -5,-0.1 -4,-2.2 1,-0.1 -1,-0.4 -0.431 56.5-106.6 -72.2 143.0 36.4 6.3 15.8 222 372 A L B -A 216 0A 9 -118,-2.5 2,-0.6 -6,-0.2 -6,-0.2 -0.238 25.2-127.8 -66.9 156.5 34.3 6.6 12.6 223 373 A L + 0 0 81 -8,-2.6 -8,-0.2 -6,-0.0 2,-0.1 -0.935 40.3 151.8-113.1 114.5 33.6 3.6 10.4 224 374 A L + 0 0 26 -2,-0.6 6,-0.1 1,-0.1 -2,-0.0 -0.564 3.2 158.3-139.8 69.2 34.4 3.9 6.7 225 375 A D + 0 0 134 -2,-0.1 2,-0.5 4,-0.0 -1,-0.1 0.705 59.6 71.1 -67.9 -20.4 35.3 0.5 5.4 226 376 A N S >> S- 0 0 100 1,-0.1 4,-2.1 -3,-0.1 3,-1.8 -0.866 72.9-141.8-110.4 133.1 34.5 1.4 1.9 227 377 A Y H 3> S+ 0 0 80 -2,-0.5 4,-3.3 1,-0.3 5,-0.3 0.845 99.6 68.7 -49.2 -41.0 36.4 3.7 -0.4 228 378 A T H 34 S+ 0 0 96 1,-0.2 4,-0.3 2,-0.2 -1,-0.3 0.805 109.4 35.3 -52.5 -33.0 33.1 5.1 -1.8 229 379 A D H X> S+ 0 0 53 -3,-1.8 4,-1.4 2,-0.1 3,-0.6 0.864 116.1 54.7 -87.5 -41.3 32.5 6.8 1.5 230 380 A R H 3X S+ 0 0 28 -4,-2.1 4,-2.4 1,-0.2 3,-0.3 0.891 103.1 54.6 -60.6 -42.1 36.1 7.6 2.3 231 381 A I H 3X S+ 0 0 8 -4,-3.3 4,-2.0 1,-0.2 -1,-0.2 0.784 105.7 54.3 -64.0 -25.2 36.7 9.5 -1.0 232 382 A Q H <> S+ 0 0 47 -3,-0.6 4,-1.4 -5,-0.3 -1,-0.2 0.857 110.7 45.7 -74.6 -35.1 33.7 11.7 -0.1 233 383 A V H X S+ 0 0 1 -4,-1.4 4,-1.7 -3,-0.3 -2,-0.2 0.862 113.4 49.6 -74.4 -36.2 35.3 12.6 3.2 234 384 A L H X S+ 0 0 0 -4,-2.4 4,-2.1 2,-0.2 5,-0.2 0.880 108.1 52.9 -69.9 -39.7 38.7 13.2 1.7 235 385 A R H X S+ 0 0 37 -4,-2.0 4,-1.4 1,-0.2 -1,-0.2 0.907 113.7 44.2 -61.4 -41.3 37.3 15.5 -1.0 236 386 A N H X S+ 0 0 0 -4,-1.4 4,-2.3 2,-0.2 -1,-0.2 0.794 109.0 57.0 -73.6 -30.7 35.6 17.5 1.8 237 387 A M H X S+ 0 0 0 -4,-1.7 4,-2.1 2,-0.2 -2,-0.2 0.924 109.7 43.3 -67.3 -44.7 38.7 17.5 4.0 238 388 A V H X S+ 0 0 0 -4,-2.1 4,-2.3 2,-0.2 -1,-0.2 0.867 113.4 53.4 -68.6 -33.4 40.9 19.1 1.3 239 389 A H H X S+ 0 0 0 -4,-1.4 4,-1.5 -5,-0.2 -2,-0.2 0.902 109.6 48.1 -65.2 -41.7 38.1 21.5 0.5 240 390 A C H < S+ 0 0 0 -4,-2.3 -2,-0.2 2,-0.2 -1,-0.2 0.851 110.2 51.6 -66.3 -37.2 38.0 22.4 4.2 241 391 A A H >< S+ 0 0 0 -4,-2.1 3,-1.3 1,-0.2 -2,-0.2 0.910 109.3 50.7 -64.9 -41.5 41.7 22.9 4.2 242 392 A D H 3< S+ 0 0 10 -4,-2.3 3,-0.3 1,-0.3 -2,-0.2 0.821 116.9 40.6 -65.5 -32.1 41.4 25.1 1.2 243 393 A L T 3< S+ 0 0 10 -4,-1.5 -1,-0.3 1,-0.2 -2,-0.2 -0.193 87.1 103.8-108.6 40.4 38.7 27.1 3.1 244 394 A S X + 0 0 0 -3,-1.3 3,-1.9 1,-0.1 4,-0.4 0.540 44.8 96.9 -99.1 -7.5 40.5 27.1 6.5 245 395 A N G > S+ 0 0 15 -3,-0.3 3,-1.5 1,-0.3 -1,-0.1 0.880 83.5 51.7 -49.4 -47.9 41.8 30.7 6.6 246 396 A P G 3 S+ 0 0 2 0, 0.0 -1,-0.3 0, 0.0 80,-0.2 0.635 105.4 58.2 -67.0 -11.4 38.9 32.0 8.7 247 397 A T G < S+ 0 0 1 -3,-1.9 -2,-0.2 79,-0.1 76,-0.2 0.444 92.6 84.9 -96.6 -3.0 39.4 29.2 11.2 248 398 A K S < S- 0 0 4 -3,-1.5 -221,-0.1 -4,-0.4 78,-0.1 -0.330 99.9 -58.8 -90.5 177.3 43.1 30.2 12.0 249 399 A S >> - 0 0 71 1,-0.1 4,-3.0 -2,-0.1 3,-0.5 -0.220 52.1-115.4 -54.4 145.9 44.3 32.8 14.4 250 400 A L H 3> S+ 0 0 48 1,-0.2 4,-3.1 2,-0.2 5,-0.2 0.863 116.7 57.6 -52.5 -39.1 42.9 36.2 13.7 251 401 A E H 3> S+ 0 0 120 2,-0.2 4,-1.1 1,-0.2 -1,-0.2 0.904 112.2 39.3 -59.5 -44.0 46.5 37.4 13.0 252 402 A L H X> S+ 0 0 10 -3,-0.5 4,-2.1 2,-0.2 3,-0.6 0.955 115.1 53.2 -70.3 -50.7 46.9 34.7 10.3 253 403 A Y H 3X S+ 0 0 1 -4,-3.0 4,-2.6 1,-0.2 -2,-0.2 0.897 105.3 53.8 -51.3 -47.9 43.4 35.2 9.0 254 404 A R H 3X S+ 0 0 120 -4,-3.1 4,-2.0 1,-0.2 -1,-0.2 0.866 109.1 49.4 -59.0 -35.8 43.8 38.9 8.5 255 405 A Q H <>S+ 0 0 0 -4,-2.7 5,-3.0 1,-0.2 3,-0.7 0.921 115.8 50.6 -60.9 -45.0 39.1 43.4 -16.5 272 422 A R H ><5S+ 0 0 73 -4,-2.4 3,-1.5 1,-0.3 -2,-0.2 0.920 108.2 50.7 -58.7 -48.8 39.1 47.2 -16.2 273 423 A E H 3<5S+ 0 0 174 -4,-2.9 -1,-0.3 1,-0.3 -2,-0.2 0.640 109.3 53.8 -67.4 -14.3 42.0 47.7 -18.5 274 424 A R T <<5S- 0 0 133 -4,-0.8 -1,-0.3 -3,-0.7 -2,-0.2 0.004 117.0-109.6-108.5 26.8 40.3 45.5 -21.1 275 425 A G T < 5S+ 0 0 74 -3,-1.5 -3,-0.2 1,-0.2 -2,-0.1 0.730 75.1 144.5 54.5 19.0 37.0 47.4 -21.1 276 426 A M < - 0 0 38 -5,-3.0 2,-0.6 -6,-0.2 -1,-0.2 -0.450 60.7 -99.3 -86.0 164.0 35.6 44.4 -19.3 277 427 A E - 0 0 161 -2,-0.1 2,-0.1 -3,-0.1 -1,-0.1 -0.740 45.2-114.8 -84.8 121.6 32.9 44.5 -16.7 278 428 A I - 0 0 50 -2,-0.6 5,-0.1 1,-0.1 3,-0.1 -0.335 29.7-124.3 -62.6 128.6 34.6 44.2 -13.2 279 429 A S > - 0 0 23 1,-0.1 3,-1.6 -15,-0.1 4,-0.3 -0.265 39.3 -76.8 -69.9 157.8 33.7 41.0 -11.4 280 430 A P T 3 S+ 0 0 117 0, 0.0 -1,-0.1 0, 0.0 7,-0.0 -0.301 117.8 11.2 -58.2 134.6 32.2 41.0 -7.8 281 431 A M T 3 S+ 0 0 59 2,-0.1 -13,-0.1 -3,-0.1 6,-0.1 0.148 107.7 92.5 82.8 -17.2 34.8 41.7 -5.1 282 432 A C < + 0 0 4 -3,-1.6 2,-1.0 -15,-0.1 -14,-0.2 0.457 55.9 95.9 -88.9 -1.0 37.3 42.8 -7.7 283 433 A D >> - 0 0 37 -4,-0.3 3,-2.0 1,-0.2 4,-1.0 -0.786 53.6-167.6 -95.2 103.1 36.5 46.5 -7.7 284 434 A K T 34 S+ 0 0 95 -2,-1.0 -1,-0.2 1,-0.3 -19,-0.1 0.627 86.9 60.0 -61.2 -14.7 39.0 48.2 -5.3 285 435 A H T 34 S+ 0 0 134 1,-0.1 -1,-0.3 -3,-0.1 -2,-0.0 0.506 119.6 22.3 -93.0 -6.4 36.8 51.3 -5.5 286 436 A T T <4 S+ 0 0 106 -3,-2.0 2,-0.2 -5,-0.0 -2,-0.2 0.251 87.3 130.6-142.4 11.8 33.7 49.7 -4.1 287 437 A A < - 0 0 34 -4,-1.0 2,-0.7 -6,-0.1 -5,-0.0 -0.507 40.3-159.0 -76.3 137.4 34.9 46.6 -2.2 288 438 A S > - 0 0 48 -2,-0.2 4,-2.3 1,-0.2 5,-0.2 -0.808 12.1-177.2-116.2 85.8 33.6 46.1 1.4 289 439 A V H > S+ 0 0 35 -2,-0.7 4,-1.9 1,-0.2 -1,-0.2 0.894 76.9 42.4 -50.1 -55.5 36.2 43.8 2.9 290 440 A E H > S+ 0 0 56 1,-0.2 4,-1.9 2,-0.2 -1,-0.2 0.926 115.1 48.1 -63.2 -48.4 34.7 43.3 6.3 291 441 A K H > S+ 0 0 139 1,-0.2 4,-1.9 2,-0.2 -1,-0.2 0.876 111.4 53.3 -61.8 -35.4 31.1 42.8 5.2 292 442 A S H X S+ 0 0 32 -4,-2.3 4,-2.9 2,-0.2 -1,-0.2 0.892 105.2 52.2 -68.3 -39.7 32.3 40.4 2.5 293 443 A Q H X S+ 0 0 14 -4,-1.9 4,-2.6 1,-0.2 5,-0.2 0.926 108.9 51.5 -62.5 -40.0 34.2 38.2 5.0 294 444 A V H X S+ 0 0 13 -4,-1.9 4,-2.8 1,-0.2 -1,-0.2 0.908 112.4 45.7 -62.3 -41.4 31.1 38.0 7.1 295 445 A G H X S+ 0 0 23 -4,-1.9 4,-2.7 2,-0.2 5,-0.5 0.917 109.8 55.1 -66.4 -42.2 29.1 36.9 4.1 296 446 A F H X>S+ 0 0 65 -4,-2.9 4,-2.1 2,-0.2 5,-1.8 0.938 115.0 39.1 -54.3 -51.1 31.9 34.4 3.1 297 447 A I H <>S+ 0 0 1 -4,-2.6 5,-2.7 3,-0.2 -2,-0.2 0.958 116.1 49.0 -66.2 -54.7 31.7 32.8 6.5 298 448 A D H <5S+ 0 0 68 -4,-2.8 -2,-0.2 -5,-0.2 -1,-0.2 0.887 123.6 30.4 -54.5 -45.0 27.9 32.9 7.0 299 449 A Y H <5S+ 0 0 191 -4,-2.7 -1,-0.2 -5,-0.2 -2,-0.2 0.797 138.1 5.3 -88.7 -29.0 27.1 31.4 3.5 300 450 A I T X5S+ 0 0 64 -4,-2.1 4,-1.4 -5,-0.5 -3,-0.2 0.792 122.3 42.6-122.1 -57.5 30.0 29.2 2.8 301 451 A V H > S+ 0 0 30 0, 0.0 4,-1.2 0, 0.0 -1,-0.2 0.890 114.2 44.5 -53.4 -38.2 28.1 25.8 6.8 304 454 A L H X S+ 0 0 0 -4,-1.4 4,-2.1 2,-0.2 -2,-0.2 0.956 115.6 43.3 -71.2 -52.3 30.9 23.6 5.7 305 455 A W H X S+ 0 0 1 -4,-2.5 4,-2.7 1,-0.2 -1,-0.2 0.805 109.4 58.3 -66.8 -29.2 32.9 23.5 9.0 306 456 A E H X S+ 0 0 89 -4,-2.8 4,-1.6 -5,-0.2 -1,-0.2 0.917 109.7 44.1 -64.6 -42.6 29.8 23.0 11.1 307 457 A T H X S+ 0 0 10 -4,-1.2 4,-1.9 -5,-0.3 -2,-0.2 0.881 113.7 50.5 -69.4 -38.1 29.0 19.9 9.2 308 458 A W H X S+ 0 0 0 -4,-2.1 4,-2.1 1,-0.2 -2,-0.2 0.901 108.7 52.3 -66.3 -39.6 32.7 18.7 9.4 309 459 A A H < S+ 0 0 6 -4,-2.7 4,-0.3 1,-0.2 7,-0.3 0.855 108.0 51.7 -64.1 -35.1 32.6 19.4 13.1 310 460 A D H >< S+ 0 0 74 -4,-1.6 3,-0.6 2,-0.2 -1,-0.2 0.895 107.9 52.7 -67.6 -39.9 29.5 17.2 13.4 311 461 A L H 3< S+ 0 0 6 -4,-1.9 -2,-0.2 1,-0.2 -1,-0.2 0.918 123.3 26.6 -61.7 -46.1 31.2 14.4 11.5 312 462 A V T >< S- 0 0 0 -4,-2.1 3,-2.2 -5,-0.1 -208,-0.3 0.147 101.2-159.0-105.4 18.6 34.3 14.4 13.8 313 463 A Q T < + 0 0 128 -3,-0.6 -3,-0.1 -4,-0.3 -4,-0.0 -0.062 65.1 7.4 -42.0 134.1 32.6 15.7 17.0 314 464 A P T > S+ 0 0 93 0, 0.0 3,-1.8 0, 0.0 -1,-0.3 -0.889 108.9 81.5-105.9 20.6 34.1 17.0 19.2 315 465 A D T < S+ 0 0 63 -3,-2.2 3,-0.3 1,-0.3 4,-0.2 0.797 99.3 42.7 -54.3 -33.8 37.6 17.2 17.7 316 466 A A T 3> S+ 0 0 3 -7,-0.3 4,-1.9 1,-0.2 -1,-0.3 0.169 79.4 107.3-102.8 20.2 36.9 20.3 15.6 317 467 A Q H <> S+ 0 0 88 -3,-1.8 4,-2.7 1,-0.2 -1,-0.2 0.912 79.7 49.4 -64.2 -43.6 35.0 22.4 18.3 318 468 A D H > S+ 0 0 124 -4,-0.3 4,-2.7 -3,-0.3 -1,-0.2 0.867 109.1 53.8 -64.1 -34.1 37.8 24.8 18.9 319 469 A I H > S+ 0 0 25 2,-0.2 4,-2.3 1,-0.2 -1,-0.2 0.920 110.8 46.1 -64.8 -42.9 38.2 25.4 15.2 320 470 A L H X S+ 0 0 22 -4,-1.9 4,-2.6 2,-0.2 -2,-0.2 0.897 111.2 52.8 -65.2 -41.2 34.5 26.2 15.0 321 471 A D H X S+ 0 0 69 -4,-2.7 4,-2.7 1,-0.2 -2,-0.2 0.954 110.0 47.7 -58.0 -50.8 34.8 28.5 18.0 322 472 A T H X S+ 0 0 45 -4,-2.7 4,-2.9 1,-0.2 5,-0.2 0.910 110.2 53.0 -57.1 -44.4 37.7 30.4 16.4 323 473 A L H X S+ 0 0 0 -4,-2.3 4,-2.2 1,-0.2 -1,-0.2 0.939 110.8 46.7 -57.3 -47.6 35.7 30.7 13.2 324 474 A E H X S+ 0 0 69 -4,-2.6 4,-2.3 1,-0.2 -1,-0.2 0.909 112.3 49.9 -62.1 -43.9 32.7 32.2 15.0 325 475 A D H X S+ 0 0 105 -4,-2.7 4,-2.0 1,-0.2 -1,-0.2 0.920 111.3 48.4 -61.9 -43.8 35.0 34.6 17.0 326 476 A N H X S+ 0 0 10 -4,-2.9 4,-2.2 -80,-0.2 5,-0.2 0.873 109.5 54.5 -64.0 -36.6 36.7 35.7 13.8 327 477 A R H X S+ 0 0 39 -4,-2.2 4,-1.9 -5,-0.2 -2,-0.2 0.942 108.9 46.5 -61.4 -49.9 33.3 36.2 12.1 328 478 A N H X S+ 0 0 63 -4,-2.3 4,-1.7 1,-0.2 -1,-0.2 0.850 109.8 55.8 -63.5 -34.2 32.0 38.4 14.9 329 479 A W H X S+ 0 0 70 -4,-2.0 4,-0.8 2,-0.2 3,-0.4 0.961 109.2 43.6 -63.9 -52.6 35.3 40.4 14.8 330 480 A Y H >< S+ 0 0 10 -4,-2.2 3,-0.5 1,-0.2 4,-0.2 0.850 111.6 57.3 -61.2 -31.1 35.0 41.3 11.1 331 481 A Q H >< S+ 0 0 91 -4,-1.9 3,-0.8 1,-0.2 -1,-0.2 0.854 105.4 49.3 -66.8 -34.6 31.3 42.0 11.8 332 482 A S H 3< S+ 0 0 75 -4,-1.7 -1,-0.2 -3,-0.4 -2,-0.2 0.595 106.3 58.5 -79.2 -11.9 32.3 44.6 14.4 333 483 A M T << S+ 0 0 86 -4,-0.8 -1,-0.2 -3,-0.5 -2,-0.2 0.383 75.1 113.6 -97.2 1.1 34.8 46.1 11.9 334 484 A I < 0 0 59 -3,-0.8 -3,-0.0 -4,-0.2 -46,-0.0 -0.649 360.0 360.0 -75.5 117.0 32.1 46.9 9.4 335 485 A P 0 0 146 0, 0.0 -2,-0.1 0, 0.0 -1,-0.1 -0.153 360.0 360.0 -63.8 360.0 31.8 50.7 9.2