==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=13-NOV-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 09-OCT-03 1R54 . COMPND 2 MOLECULE: ADAM 33; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR P.ORTH,P.REICHER,W.WANG,W.W.PROSISE,T.YAROSH-TOMAINE,G.HAMMO . 206 1 3 3 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 9878.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 139 67.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 25 12.1 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 3 1.5 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 12 5.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 21 10.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 62 30.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 5 2.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 1 0 0 0 0 0 1 0 0 1 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 0 0 0 2 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 204 A E 0 0 251 0, 0.0 2,-0.3 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0-173.5 21.2 50.0 22.8 2 205 A A - 0 0 97 0, 0.0 2,-0.4 0, 0.0 0, 0.0 -0.957 360.0-112.6-142.8 158.7 20.2 49.0 26.3 3 206 A R - 0 0 100 -2,-0.3 2,-0.3 3,-0.0 3,-0.0 -0.805 26.6-136.1 -97.4 132.2 21.0 46.3 28.8 4 207 A R - 0 0 75 -2,-0.4 2,-0.4 1,-0.1 45,-0.0 -0.667 27.1-108.7 -86.3 140.2 18.3 43.8 29.8 5 208 A T - 0 0 121 -2,-0.3 -1,-0.1 1,-0.1 2,-0.0 -0.537 37.4-127.7 -69.7 123.8 17.9 43.0 33.5 6 209 A R - 0 0 102 -2,-0.4 2,-0.3 44,-0.0 44,-0.2 -0.321 16.0-146.5 -72.5 155.6 19.1 39.4 34.0 7 210 A K E -a 50 0A 42 42,-1.9 44,-2.8 -2,-0.0 2,-0.4 -0.881 8.2-147.0-119.3 152.6 17.0 36.8 35.8 8 211 A Y E -a 51 0A 59 194,-2.4 2,-0.7 -2,-0.3 44,-0.2 -0.985 4.2-156.5-128.9 130.0 18.3 34.0 38.0 9 212 A L E -a 52 0A 1 42,-2.4 44,-2.7 -2,-0.4 2,-1.0 -0.904 12.2-150.1-105.1 109.5 17.0 30.5 38.5 10 213 A E E -a 53 0A 37 -2,-0.7 83,-2.3 191,-0.2 84,-1.8 -0.716 26.1-164.3 -81.0 107.8 18.1 29.1 41.8 11 214 A L E -ab 54 94A 0 42,-2.4 44,-2.0 -2,-1.0 45,-1.1 -0.808 21.8-167.6-105.0 134.6 18.1 25.4 40.9 12 215 A Y E -ab 56 95A 2 82,-2.4 84,-2.8 -2,-0.4 2,-0.4 -0.981 17.9-162.9-116.2 120.7 18.3 22.3 43.2 13 216 A I E -ab 57 96A 0 43,-2.3 45,-1.6 -2,-0.5 2,-0.4 -0.895 5.2-166.3-115.1 138.1 19.0 19.1 41.3 14 217 A V E -ab 58 97A 0 82,-2.9 84,-3.2 -2,-0.4 2,-0.5 -0.950 11.7-154.8-123.9 136.8 18.5 15.6 42.5 15 218 A A E -ab 59 98A 0 43,-2.6 45,-2.5 -2,-0.4 84,-0.2 -0.941 24.5-138.5-107.3 124.7 19.7 12.2 41.2 16 219 A D > - 0 0 0 82,-1.9 4,-1.8 -2,-0.5 3,-0.2 -0.172 28.7 -96.6 -75.9 175.8 17.4 9.3 42.1 17 220 A H H > S+ 0 0 29 1,-0.2 4,-2.7 2,-0.2 5,-0.2 0.877 121.6 55.8 -62.0 -39.8 18.7 5.9 43.3 18 221 A T H > S+ 0 0 38 1,-0.2 4,-2.4 2,-0.2 -1,-0.2 0.884 107.1 49.5 -62.2 -38.5 18.4 4.3 39.8 19 222 A L H > S+ 0 0 3 2,-0.2 4,-1.9 79,-0.2 -1,-0.2 0.913 110.6 51.5 -66.1 -39.6 20.6 7.0 38.3 20 223 A F H <>S+ 0 0 13 -4,-1.8 5,-2.2 1,-0.2 6,-0.5 0.931 110.9 47.4 -60.5 -44.8 23.1 6.4 41.1 21 224 A L H ><5S+ 0 0 72 -4,-2.7 3,-1.2 1,-0.2 -1,-0.2 0.890 108.7 55.2 -64.1 -38.0 23.0 2.6 40.4 22 225 A T H 3<5S+ 0 0 71 -4,-2.4 -1,-0.2 1,-0.3 -2,-0.2 0.858 102.8 56.0 -61.8 -37.4 23.5 3.4 36.7 23 226 A R T ><5S- 0 0 70 -4,-1.9 3,-1.8 -5,-0.1 -1,-0.3 -0.098 126.7-101.6 -87.4 34.2 26.6 5.4 37.5 24 227 A H T < 5 - 0 0 170 -3,-1.2 -3,-0.2 1,-0.3 -2,-0.2 0.802 66.2 -67.7 48.9 40.3 28.0 2.2 39.3 25 228 A R T 3 - 0 0 63 -3,-1.8 4,-1.7 -6,-0.5 -1,-0.2 -0.842 29.0-170.6 -98.1 105.1 29.8 6.2 42.2 27 230 A L H > S+ 0 0 73 -2,-0.9 4,-2.6 1,-0.2 3,-0.2 0.946 84.7 49.8 -58.9 -51.8 28.8 9.3 44.3 28 231 A Q H > S+ 0 0 121 1,-0.2 4,-2.0 2,-0.2 -1,-0.2 0.902 114.2 44.1 -55.3 -46.8 31.4 11.6 42.8 29 232 A H H > S+ 0 0 109 2,-0.2 4,-1.5 1,-0.2 -1,-0.2 0.755 110.9 54.5 -73.8 -22.9 30.6 10.7 39.2 30 233 A T H X S+ 0 0 0 -4,-1.7 4,-1.9 -3,-0.2 -2,-0.2 0.913 110.5 46.5 -73.9 -41.8 26.9 10.9 39.9 31 234 A K H X S+ 0 0 77 -4,-2.6 4,-2.3 1,-0.2 -2,-0.2 0.883 109.3 55.0 -65.2 -37.9 27.3 14.4 41.2 32 235 A Q H X S+ 0 0 81 -4,-2.0 4,-2.3 -5,-0.2 -1,-0.2 0.897 106.5 51.6 -62.5 -38.8 29.6 15.3 38.2 33 236 A R H X S+ 0 0 11 -4,-1.5 4,-2.5 2,-0.2 -1,-0.2 0.920 109.3 49.2 -64.0 -43.9 26.8 14.2 35.9 34 237 A L H X S+ 0 0 0 -4,-1.9 4,-2.6 1,-0.2 -1,-0.2 0.889 111.4 50.2 -61.9 -40.3 24.2 16.4 37.6 35 238 A L H X S+ 0 0 66 -4,-2.3 4,-2.1 2,-0.2 -1,-0.2 0.897 111.2 47.9 -66.2 -40.0 26.7 19.3 37.4 36 239 A E H X S+ 0 0 78 -4,-2.3 4,-1.8 2,-0.2 -2,-0.2 0.898 112.3 49.0 -69.5 -38.3 27.3 18.8 33.7 37 240 A V H X S+ 0 0 0 -4,-2.5 4,-2.1 1,-0.2 -2,-0.2 0.936 111.3 49.7 -65.7 -43.0 23.5 18.5 33.0 38 241 A A H X S+ 0 0 5 -4,-2.6 4,-2.6 1,-0.2 -2,-0.2 0.892 106.0 58.4 -61.3 -37.8 23.0 21.7 35.0 39 242 A N H X S+ 0 0 81 -4,-2.1 4,-2.1 1,-0.2 -1,-0.2 0.909 108.5 43.9 -57.3 -45.3 25.7 23.4 33.0 40 243 A Y H X S+ 0 0 59 -4,-1.8 4,-2.5 2,-0.2 -1,-0.2 0.849 110.2 55.5 -70.9 -33.0 23.9 22.7 29.7 41 244 A V H X S+ 0 0 0 -4,-2.1 4,-2.8 2,-0.2 5,-0.2 0.924 108.1 50.0 -64.0 -40.2 20.6 23.8 31.3 42 245 A D H X S+ 0 0 20 -4,-2.6 4,-1.9 2,-0.2 -2,-0.2 0.933 109.2 51.0 -62.0 -46.1 22.3 27.1 32.1 43 246 A Q H X S+ 0 0 72 -4,-2.1 4,-0.6 1,-0.2 -2,-0.2 0.946 114.0 44.3 -56.7 -49.8 23.6 27.5 28.6 44 247 A L H >< S+ 0 0 0 -4,-2.5 3,-1.3 1,-0.2 138,-0.3 0.929 113.0 49.3 -62.0 -48.4 20.1 26.9 27.1 45 248 A L H ><>S+ 0 0 0 -4,-2.8 3,-2.4 1,-0.3 5,-1.9 0.784 96.8 71.1 -64.9 -26.1 18.3 29.2 29.6 46 249 A R H ><5S+ 0 0 102 -4,-1.9 3,-2.0 1,-0.3 -1,-0.3 0.809 86.2 65.2 -62.2 -25.3 20.7 32.0 29.0 47 250 A T T <<5S+ 0 0 35 -3,-1.3 -1,-0.3 -4,-0.6 -2,-0.2 0.564 102.8 50.1 -72.4 -4.3 19.2 32.4 25.6 48 251 A L T < 5S- 0 0 6 -3,-2.4 -1,-0.3 2,-0.3 -2,-0.2 0.232 124.8-107.8-109.8 6.0 16.1 33.4 27.6 49 252 A D T < 5S+ 0 0 45 -3,-2.0 -42,-1.9 1,-0.3 2,-0.5 0.744 82.1 128.6 70.6 24.1 18.2 35.9 29.7 50 253 A I E < -a 7 0A 1 -5,-1.9 2,-0.4 -44,-0.2 -2,-0.3 -0.950 44.3-158.3-113.4 128.6 18.0 33.5 32.6 51 254 A Q E -a 8 0A 58 -44,-2.8 -42,-2.4 -2,-0.5 2,-0.4 -0.898 16.5-126.9-108.6 134.2 21.1 32.4 34.4 52 255 A V E -a 9 0A 21 -2,-0.4 2,-0.5 -44,-0.2 -42,-0.2 -0.641 18.5-169.9 -84.1 133.9 21.3 29.3 36.5 53 256 A A E -a 10 0A 21 -44,-2.7 -42,-2.4 -2,-0.4 2,-1.0 -0.968 21.0-139.1-120.5 108.6 22.5 29.4 40.1 54 257 A L E +a 11 0A 63 -2,-0.5 -42,-0.2 -44,-0.2 3,-0.1 -0.594 24.5 177.5 -75.3 102.3 23.0 25.9 41.5 55 258 A T E - 0 0 60 -44,-2.0 2,-0.3 -2,-1.0 -43,-0.2 0.909 61.6 -14.0 -70.3 -46.7 21.6 26.0 45.0 56 259 A G E -a 12 0A 16 -45,-1.1 -43,-2.3 34,-0.1 2,-0.3 -0.996 48.7-148.4-159.2 160.5 22.2 22.4 45.9 57 260 A L E +a 13 0A 49 -2,-0.3 2,-0.3 -45,-0.2 -43,-0.2 -0.967 19.5 179.8-128.8 143.5 22.9 18.9 44.6 58 261 A E E -a 14 0A 46 -45,-1.6 -43,-2.6 -2,-0.3 2,-0.5 -0.983 12.4-163.5-150.6 135.5 21.7 15.7 46.1 59 262 A V E -a 15 0A 17 -2,-0.3 2,-1.9 -45,-0.2 -43,-0.2 -0.984 20.0-138.9-122.0 126.2 22.1 12.0 45.3 60 263 A W + 0 0 4 -45,-2.5 -40,-0.2 -2,-0.5 -41,-0.0 -0.562 33.2 170.1 -84.7 77.9 19.8 9.3 46.8 61 264 A T S S+ 0 0 48 -2,-1.9 -1,-0.2 1,-0.1 3,-0.1 0.735 71.9 18.1 -62.0 -32.0 22.5 6.8 47.4 62 265 A E S S+ 0 0 149 1,-0.4 2,-0.3 -3,-0.2 -1,-0.1 0.784 129.8 2.6-112.6 -36.6 20.6 4.3 49.5 63 266 A R S S- 0 0 43 -46,-0.0 -1,-0.4 0, 0.0 2,-0.2 -0.997 72.4-104.3-151.6 146.5 16.9 4.8 48.9 64 267 A D - 0 0 53 -2,-0.3 -48,-0.1 1,-0.1 3,-0.1 -0.524 23.9-149.0 -68.8 138.0 14.6 7.1 46.8 65 268 A R S S+ 0 0 130 -2,-0.2 2,-0.3 1,-0.1 -1,-0.1 0.642 84.8 31.1 -83.4 -15.7 13.2 9.8 49.1 66 269 A S S S- 0 0 11 16,-0.0 2,-0.3 15,-0.0 -1,-0.1 -0.979 104.5 -87.7-138.3 147.8 10.0 9.9 46.9 67 270 A R - 0 0 66 -2,-0.3 2,-0.6 7,-0.1 11,-0.2 -0.397 40.4-168.4 -62.9 117.0 8.4 7.1 45.0 68 271 A V + 0 0 12 -2,-0.3 2,-0.2 10,-0.1 4,-0.1 -0.927 21.2 154.3-109.6 113.7 9.8 6.9 41.5 69 272 A T - 0 0 55 -2,-0.6 6,-0.1 2,-0.4 32,-0.1 -0.663 61.6 -86.7-127.8-176.6 7.8 4.6 39.2 70 273 A Q S S+ 0 0 93 -2,-0.2 34,-3.1 33,-0.1 2,-1.0 0.666 104.9 90.9 -66.6 -15.9 7.1 4.0 35.5 71 274 A D > - 0 0 79 32,-0.2 4,-2.9 1,-0.2 -2,-0.4 -0.729 61.9-167.3 -86.1 101.7 4.3 6.6 35.9 72 275 A A H > S+ 0 0 7 -2,-1.0 4,-2.5 32,-0.4 -1,-0.2 0.884 87.1 48.1 -55.8 -43.6 5.9 10.0 35.1 73 276 A N H > S+ 0 0 89 2,-0.2 4,-2.2 1,-0.2 5,-0.2 0.911 113.1 46.1 -66.7 -42.6 3.0 11.9 36.5 74 277 A A H > S+ 0 0 46 1,-0.2 4,-2.0 2,-0.2 5,-0.2 0.927 113.9 50.3 -64.7 -43.3 2.8 10.0 39.7 75 278 A T H X S+ 0 0 0 -4,-2.9 4,-2.1 1,-0.2 -2,-0.2 0.908 108.7 53.5 -60.0 -43.5 6.6 10.3 40.0 76 279 A L H X S+ 0 0 2 -4,-2.5 4,-2.3 -5,-0.2 -2,-0.2 0.952 112.0 40.8 -58.8 -54.6 6.4 14.0 39.4 77 280 A W H X S+ 0 0 109 -4,-2.2 4,-1.7 2,-0.2 -1,-0.2 0.813 112.4 54.9 -69.0 -27.7 3.9 14.8 42.2 78 281 A A H X S+ 0 0 19 -4,-2.0 4,-1.4 -5,-0.2 -1,-0.2 0.912 111.5 46.6 -68.3 -39.4 5.5 12.5 44.7 79 282 A F H X S+ 0 0 0 -4,-2.1 4,-2.3 -5,-0.2 -2,-0.2 0.890 109.9 53.6 -67.3 -39.9 8.7 14.4 44.1 80 283 A L H X S+ 0 0 1 -4,-2.3 4,-1.0 2,-0.2 -1,-0.2 0.821 106.4 51.1 -66.3 -32.2 7.0 17.7 44.4 81 284 A Q H X S+ 0 0 137 -4,-1.7 4,-0.7 1,-0.2 -1,-0.2 0.859 112.0 48.3 -73.9 -30.9 5.5 16.8 47.8 82 285 A W H >X S+ 0 0 53 -4,-1.4 4,-1.6 1,-0.2 3,-0.5 0.877 102.3 63.8 -71.7 -38.0 9.0 15.8 48.9 83 286 A R H 3X S+ 0 0 4 -4,-2.3 4,-3.0 1,-0.2 -1,-0.2 0.808 91.7 65.8 -55.1 -33.9 10.4 19.1 47.5 84 287 A R H 3X S+ 0 0 132 -4,-1.0 4,-1.4 1,-0.2 -1,-0.2 0.940 102.6 44.8 -56.1 -50.3 8.3 21.0 50.1 85 288 A G H X S+ 0 0 17 -4,-1.6 4,-3.3 1,-0.2 3,-0.7 0.919 104.1 58.5 -60.3 -46.5 13.5 20.2 51.2 87 290 A W H 3< S+ 0 0 126 -4,-3.0 -1,-0.2 1,-0.2 -2,-0.2 0.836 99.6 58.2 -53.1 -38.7 12.6 23.8 50.4 88 291 A A H 3< S+ 0 0 75 -4,-1.4 -1,-0.2 -3,-0.3 -2,-0.2 0.879 117.3 32.6 -60.9 -39.2 12.2 24.7 54.1 89 292 A Q H << S+ 0 0 158 -4,-1.0 -2,-0.2 -3,-0.7 -1,-0.2 0.815 135.5 24.0 -86.9 -35.8 15.7 23.6 54.8 90 293 A R S < S- 0 0 143 -4,-3.3 -1,-0.2 -5,-0.2 -2,-0.2 -0.699 82.4-148.2-137.1 83.8 17.3 24.6 51.5 91 294 A P + 0 0 79 0, 0.0 2,-0.3 0, 0.0 -3,-0.1 -0.112 30.6 151.9 -50.6 142.6 15.4 27.4 49.7 92 295 A H - 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