==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=11-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER LYASE(OXO-ACID) 02-APR-93 1RAZ . COMPND 2 MOLECULE: CARBONIC ANHYDRASE II; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR B.M.JONSSON,K.HAKANSSON,A.LILJAS . 258 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 11857.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 164 63.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 18 7.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 56 21.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 23 8.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 35 13.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 18 7.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 2 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 3 1 1 1 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 3 A H 0 0 237 0, 0.0 2,-0.2 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0-125.5 13.5 -1.0 8.1 2 4 A H - 0 0 118 1,-0.1 0, 0.0 0, 0.0 0, 0.0 -0.579 360.0 -83.8 -94.7 160.7 10.0 0.3 9.0 3 5 A W + 0 0 35 -2,-0.2 2,-0.2 1,-0.1 7,-0.2 -0.126 61.1 132.2 -58.6 154.2 7.7 -1.5 11.4 4 6 A G - 0 0 10 5,-2.3 10,-0.1 2,-0.2 -1,-0.1 -0.725 64.0 -86.4-167.8-147.1 5.4 -4.4 10.4 5 7 A Y S S+ 0 0 29 -2,-0.2 5,-0.2 5,-0.2 237,-0.1 0.118 82.7 110.2-129.7 6.9 4.5 -7.8 11.7 6 8 A G S > S- 0 0 40 4,-0.1 4,-1.4 1,-0.0 3,-0.2 -0.210 85.4 -91.7 -77.5 178.9 7.2 -9.9 10.0 7 9 A K T 4 S+ 0 0 151 1,-0.2 3,-0.2 2,-0.2 5,-0.1 0.887 123.2 39.2 -56.6 -52.5 10.1 -11.6 11.9 8 10 A H T 4 S+ 0 0 162 1,-0.2 -1,-0.2 4,-0.0 -5,-0.0 0.654 129.9 27.6 -80.9 -15.5 12.6 -8.8 11.7 9 11 A N T 4 S+ 0 0 52 -3,-0.2 -5,-2.3 -6,-0.1 -2,-0.2 0.255 90.0 131.9-131.8 13.6 10.2 -5.9 12.2 10 12 A G S >< S- 0 0 0 -4,-1.4 3,-3.0 -5,-0.2 4,-0.4 0.028 78.5 -80.4 -62.3 172.3 7.4 -7.5 14.3 11 13 A P G >> S+ 0 0 25 0, 0.0 3,-0.9 0, 0.0 4,-0.5 0.698 125.6 68.9 -50.2 -26.6 5.9 -6.1 17.5 12 14 A E G 34 S+ 0 0 108 1,-0.3 -2,-0.1 2,-0.1 -7,-0.0 0.602 103.7 45.5 -69.8 -11.8 8.9 -7.3 19.5 13 15 A H G X> S+ 0 0 53 -3,-3.0 3,-1.4 2,-0.1 4,-0.6 0.495 84.5 90.8-107.0 -11.4 10.9 -4.7 17.7 14 16 A W H X> S+ 0 0 4 -3,-0.9 4,-2.4 -4,-0.4 3,-1.2 0.889 74.0 70.9 -60.0 -34.1 8.6 -1.7 18.0 15 17 A H H 3< S+ 0 0 68 -4,-0.5 -1,-0.3 1,-0.2 7,-0.1 0.756 88.1 63.7 -52.0 -33.1 10.2 -0.6 21.3 16 18 A K H <4 S+ 0 0 133 -3,-1.4 -1,-0.2 1,-0.2 -2,-0.2 0.862 119.0 23.0 -62.8 -37.2 13.5 0.5 19.5 17 19 A D H << S+ 0 0 114 -3,-1.2 -2,-0.2 -4,-0.6 -1,-0.2 0.627 134.2 38.0-100.3 -22.7 11.7 3.2 17.4 18 20 A F >< - 0 0 58 -4,-2.4 3,-2.4 1,-0.1 -1,-0.2 -0.794 64.2-177.2-134.8 86.2 8.7 3.8 19.7 19 21 A P G > S+ 0 0 101 0, 0.0 3,-2.1 0, 0.0 -4,-0.1 0.729 77.0 77.6 -58.9 -22.7 10.0 3.5 23.3 20 22 A I G > + 0 0 51 1,-0.3 3,-2.2 2,-0.2 -5,-0.1 0.622 69.6 86.4 -60.3 -18.7 6.4 4.0 24.4 21 23 A A G < S+ 0 0 6 -3,-2.4 -1,-0.3 1,-0.3 -6,-0.1 0.629 92.5 44.4 -53.3 -27.5 5.9 0.4 23.4 22 24 A K G < S+ 0 0 138 -3,-2.1 -1,-0.3 -7,-0.1 -2,-0.2 0.221 94.6 122.5-104.2 11.5 7.0 -0.5 27.0 23 25 A G S < S- 0 0 17 -3,-2.2 3,-0.4 -4,-0.1 -3,-0.0 0.184 74.1 -98.9 -61.2-174.1 4.9 2.3 28.6 24 26 A E S S+ 0 0 116 1,-0.2 226,-0.2 225,-0.0 -1,-0.1 0.471 110.6 41.9 -89.5 -16.7 2.3 2.0 31.3 25 27 A R S S+ 0 0 52 224,-0.1 179,-0.2 2,-0.1 -1,-0.2 -0.160 79.7 154.1-134.6 42.6 -1.0 2.0 29.4 26 28 A Q - 0 0 3 -3,-0.4 220,-0.2 221,-0.2 170,-0.1 -0.298 32.5-104.3 -74.3 145.2 -0.2 -0.2 26.5 27 29 A S S S+ 0 0 0 168,-0.4 2,-0.2 -2,-0.1 -2,-0.1 -0.909 75.4 38.6-125.3 158.8 -2.7 -2.2 24.5 28 30 A P + 0 0 0 0, 0.0 218,-2.2 0, 0.0 2,-0.3 0.595 64.8 172.0 -79.7-178.3 -4.0 -4.8 23.8 29 31 A V - 0 0 1 216,-0.3 77,-1.1 -2,-0.2 2,-0.4 -0.929 39.0 -94.9-143.5 169.7 -4.3 -6.8 27.1 30 32 A D E -a 106 0A 37 216,-0.5 2,-0.7 -2,-0.3 77,-0.2 -0.706 35.4-136.8 -91.6 131.3 -6.0 -10.0 28.2 31 33 A I E -a 107 0A 0 75,-3.1 77,-3.3 -2,-0.4 2,-0.9 -0.866 12.7-158.5 -92.1 117.7 -9.4 -9.4 29.7 32 34 A D >> - 0 0 61 -2,-0.7 4,-1.1 75,-0.2 3,-1.0 -0.867 1.3-162.2 -98.6 98.9 -9.7 -11.5 32.9 33 35 A T T 34 S+ 0 0 47 -2,-0.9 -1,-0.1 1,-0.3 222,-0.0 0.701 86.3 52.1 -58.6 -21.3 -13.5 -11.8 33.4 34 36 A H T 34 S+ 0 0 163 1,-0.2 -1,-0.3 3,-0.0 -3,-0.0 0.743 113.3 42.3 -90.2 -19.7 -13.2 -12.8 37.0 35 37 A T T <4 S+ 0 0 103 -3,-1.0 2,-0.3 2,-0.1 218,-0.2 0.476 89.5 105.0-102.2 -4.9 -11.0 -9.9 38.1 36 38 A A S < S- 0 0 17 -4,-1.1 2,-0.6 216,-0.1 218,-0.2 -0.599 72.2-127.2 -78.0 135.5 -12.8 -7.2 36.1 37 39 A K E -c 254 0B 114 216,-2.5 218,-2.4 -2,-0.3 2,-0.4 -0.781 8.5-136.3 -93.0 123.1 -15.0 -5.0 38.3 38 40 A Y E -c 255 0B 79 -2,-0.6 218,-0.2 216,-0.2 220,-0.1 -0.658 25.1-163.9 -69.7 128.5 -18.6 -4.6 37.5 39 41 A D > - 0 0 25 216,-2.4 3,-1.1 -2,-0.4 215,-0.0 -0.986 14.1-164.7-120.9 116.6 -19.1 -0.8 37.9 40 42 A P T 3 S+ 0 0 95 0, 0.0 -1,-0.1 0, 0.0 216,-0.1 0.423 83.9 69.6 -80.4 -1.3 -22.8 0.2 38.2 41 43 A S T 3 S+ 0 0 79 2,-0.1 2,-0.4 40,-0.0 215,-0.1 0.533 73.3 102.3 -91.8 -11.8 -21.9 3.9 37.6 42 44 A L < - 0 0 26 -3,-1.1 3,-0.1 213,-0.2 38,-0.0 -0.675 68.6-142.4 -75.2 131.9 -21.0 3.2 33.9 43 45 A K - 0 0 105 37,-1.0 2,-0.1 -2,-0.4 39,-0.1 -0.357 27.1 -84.7 -85.4 165.6 -23.8 4.4 31.7 44 46 A P - 0 0 107 0, 0.0 36,-1.5 0, 0.0 -1,-0.1 -0.419 50.7-101.5 -72.6 150.9 -25.0 2.6 28.6 45 47 A L E -D 79 0B 19 34,-0.3 2,-0.5 141,-0.3 34,-0.2 -0.339 26.1-144.5 -71.6 157.4 -23.2 3.4 25.3 46 48 A S E -D 78 0B 52 32,-2.1 32,-1.7 -2,-0.1 2,-0.6 -0.982 15.7-176.0-129.6 106.9 -24.8 5.7 22.8 47 49 A V E +D 77 0B 38 -2,-0.5 2,-0.7 30,-0.2 30,-0.2 -0.937 4.0 177.6-110.8 105.6 -24.1 4.8 19.1 48 50 A S E +D 76 0B 41 28,-2.7 28,-2.1 -2,-0.6 3,-0.1 -0.865 25.7 137.3-110.7 95.1 -25.5 7.4 16.7 49 51 A Y > + 0 0 3 -2,-0.7 3,-1.9 26,-0.2 130,-0.2 0.208 32.4 108.3-120.4 12.0 -24.6 6.3 13.2 50 52 A D T 3 S+ 0 0 107 1,-0.3 25,-0.1 -3,-0.1 -1,-0.1 0.769 86.7 46.4 -63.3 -20.2 -27.8 6.9 11.3 51 53 A Q T 3 S+ 0 0 130 23,-0.7 -1,-0.3 -3,-0.1 24,-0.2 0.122 81.9 144.9-110.2 20.5 -26.0 9.8 9.6 52 54 A A < - 0 0 28 -3,-1.9 2,-0.4 22,-0.1 -3,-0.1 -0.245 30.7-164.3 -62.8 139.0 -22.8 8.1 8.7 53 55 A T - 0 0 46 16,-0.2 16,-2.2 121,-0.1 2,-0.2 -0.961 3.2-162.5-125.8 106.5 -21.0 9.0 5.5 54 56 A S E +E 68 0B 0 -2,-0.4 121,-0.6 14,-0.2 14,-0.2 -0.610 13.3 172.4 -87.6 156.1 -18.4 6.6 4.3 55 57 A L E + 0 0 81 12,-2.5 118,-3.5 1,-0.3 2,-0.3 0.641 51.1 2.5-125.0 -55.5 -16.0 7.9 1.7 56 58 A R E -EF 67 172B 85 11,-0.9 11,-2.7 116,-0.3 2,-0.4 -0.987 43.3-144.6-145.0 152.9 -13.1 5.6 0.9 57 59 A I E -EF 66 171B 0 114,-2.7 114,-2.1 -2,-0.3 2,-0.3 -0.889 30.8-176.9-109.7 145.0 -11.5 2.2 1.6 58 60 A L E -EF 65 170B 27 7,-1.3 7,-2.9 -2,-0.4 2,-0.5 -0.971 27.6-141.5-149.5 136.4 -7.7 2.3 1.6 59 61 A N E +E 64 0B 0 110,-2.9 109,-2.0 -2,-0.3 5,-0.2 -0.831 20.7 178.0 -92.2 125.2 -4.9 -0.3 1.9 60 62 A N - 0 0 25 3,-1.8 4,-0.1 -2,-0.5 107,-0.1 0.220 53.0-103.7-115.0 3.9 -2.2 1.3 4.0 61 63 A G S S+ 0 0 13 2,-0.4 3,-0.1 166,-0.2 106,-0.1 0.494 114.6 60.0 85.4 5.1 0.1 -1.7 4.1 62 64 A H S S- 0 0 49 1,-0.7 2,-0.3 165,-0.1 166,-0.1 0.539 122.8 -33.1-132.3 -20.5 -0.8 -2.7 7.7 63 65 A A S S- 0 0 2 165,-0.1 -3,-1.8 31,-0.1 -1,-0.7 -0.848 72.3 -88.1-174.6-170.6 -4.6 -3.3 7.5 64 66 A F E -E 59 0B 0 29,-0.3 2,-0.5 -2,-0.3 29,-0.4 -0.985 36.6-153.1-119.6 134.8 -7.4 -1.7 5.4 65 67 A N E -E 58 0B 20 -7,-2.9 -7,-1.3 -2,-0.4 2,-0.6 -0.926 9.3-155.0-109.2 133.6 -9.2 1.4 6.7 66 68 A V E -EG 57 91B 0 25,-2.9 25,-2.1 -2,-0.5 2,-0.3 -0.898 27.0-154.6 -98.6 122.8 -12.8 2.4 5.9 67 69 A E E -EG 56 90B 53 -11,-2.7 -12,-2.5 -2,-0.6 -11,-0.9 -0.797 8.8-160.1-104.6 145.7 -12.8 6.2 6.3 68 70 A F E -E 54 0B 10 21,-2.3 2,-0.8 -2,-0.3 -14,-0.2 -0.781 32.5 -96.8-119.5 162.5 -15.8 8.4 7.2 69 71 A D + 0 0 43 -16,-2.2 3,-0.3 -2,-0.3 6,-0.2 -0.744 41.4 173.9 -80.2 110.3 -16.5 12.1 6.9 70 72 A D + 0 0 43 -2,-0.8 -1,-0.1 1,-0.2 17,-0.1 0.015 47.1 106.4-107.7 23.0 -15.7 13.6 10.3 71 73 A S S S+ 0 0 73 1,-0.1 2,-0.3 2,-0.0 -1,-0.2 0.651 89.6 23.7 -73.1 -17.5 -16.1 17.3 9.5 72 74 A Q S S- 0 0 113 -3,-0.3 2,-2.2 3,-0.0 3,-0.4 -0.971 99.0 -86.3-145.7 162.8 -19.4 17.2 11.5 73 75 A D S S+ 0 0 89 -2,-0.3 3,-0.2 1,-0.2 -3,-0.1 -0.427 77.0 128.1 -66.6 78.4 -21.1 15.2 14.3 74 76 A K S S+ 0 0 51 -2,-2.2 -23,-0.7 1,-0.3 2,-0.6 0.879 73.8 24.0-102.5 -51.4 -22.5 12.6 11.9 75 77 A A S S+ 0 0 7 -3,-0.4 13,-3.8 -6,-0.2 -1,-0.3 -0.979 84.7 165.0-118.4 103.9 -21.4 9.3 13.5 76 78 A V E -DH 48 87B 9 -28,-2.1 -28,-2.7 -2,-0.6 2,-0.4 -0.898 30.3-153.6-124.4 158.7 -20.7 9.8 17.2 77 79 A L E +DH 47 86B 0 9,-2.4 9,-2.3 -2,-0.3 2,-0.3 -0.946 28.7 151.7-123.7 133.7 -20.2 7.7 20.3 78 80 A K E +D 46 0B 78 -32,-1.7 -32,-2.1 -2,-0.4 2,-0.2 -0.877 38.0 53.9-151.9 173.2 -21.1 9.2 23.7 79 81 A G E > S+D 45 0B 23 3,-0.4 3,-2.2 -2,-0.3 -34,-0.3 -0.497 72.7 73.5 91.1-165.0 -22.3 7.5 27.0 80 82 A G T 3 S- 0 0 0 -36,-1.5 -37,-1.0 1,-0.3 -1,-0.2 -0.170 121.3 -24.5 57.5-138.2 -20.4 4.6 28.7 81 83 A P T 3 S+ 0 0 38 0, 0.0 -1,-0.3 0, 0.0 2,-0.3 0.270 114.3 110.2 -86.7 7.9 -17.3 5.7 30.5 82 84 A L < - 0 0 13 -3,-2.2 -3,-0.4 -39,-0.1 2,-0.4 -0.681 53.8-153.5 -92.8 156.2 -16.9 8.8 28.1 83 85 A D - 0 0 134 -2,-0.3 -3,-0.0 53,-0.1 0, 0.0 -0.895 68.9 -4.4-119.2 133.5 -17.3 12.6 28.6 84 86 A G S S- 0 0 52 -2,-0.4 2,-0.4 39,-0.1 -5,-0.2 -0.148 102.1 -49.3 76.2-178.9 -18.3 14.7 25.5 85 87 A T - 0 0 25 -7,-0.1 38,-2.4 -9,-0.0 2,-0.4 -0.872 39.8-154.3-105.3 136.1 -18.7 13.3 22.0 86 88 A Y E -HI 77 122B 4 -9,-2.3 -9,-2.4 -2,-0.4 2,-0.4 -0.883 17.3-142.9-113.1 113.0 -16.3 11.1 20.0 87 89 A R E -HI 76 121B 45 34,-3.5 34,-2.2 -2,-0.4 2,-0.3 -0.785 18.1-115.1 -87.1 136.2 -16.6 11.4 16.2 88 90 A L E + I 0 120B 3 -13,-3.8 32,-0.3 -2,-0.4 -13,-0.2 -0.488 41.3 162.8 -70.0 118.1 -16.2 8.3 13.9 89 91 A I E - 0 0 34 30,-3.2 -21,-2.3 1,-0.4 2,-0.3 0.796 59.4 -26.4-106.2 -36.9 -13.1 8.7 11.8 90 92 A Q E -GI 67 119B 33 29,-1.0 29,-2.7 -23,-0.2 -1,-0.4 -0.975 45.6-144.5-164.7 165.9 -12.3 5.2 10.4 91 93 A F E +GI 66 118B 0 -25,-2.1 -25,-2.9 -2,-0.3 2,-0.3 -0.946 23.6 162.8-137.3 155.3 -12.7 1.4 11.1 92 94 A H E - I 0 117B 23 25,-1.7 25,-2.8 -2,-0.3 2,-0.2 -0.860 24.1-130.6-163.9 164.2 -10.2 -1.4 10.3 93 95 A F E - I 0 116B 1 -29,-0.4 2,-0.3 -2,-0.3 -29,-0.3 -0.630 0.7-145.5-121.6 164.6 -9.7 -5.0 11.4 94 96 A H E + I 0 115B 3 21,-1.2 21,-1.7 -2,-0.2 2,-0.3 -0.947 31.8 167.0-127.8 137.7 -6.8 -7.1 12.7 95 97 A W E - I 0 114B 0 -2,-0.3 146,-1.3 19,-0.2 145,-0.9 -0.959 23.4-119.9-151.5 175.5 -6.8 -10.8 11.7 96 98 A G - 0 0 0 17,-1.0 6,-0.1 5,-0.6 128,-0.1 -0.614 26.9-115.3-121.5 175.8 -4.8 -14.0 11.5 97 99 A S S S+ 0 0 44 -2,-0.2 2,-0.3 142,-0.1 5,-0.1 0.544 105.6 35.8 -76.5 -10.6 -3.4 -16.6 9.1 98 100 A L S > S- 0 0 110 3,-0.2 3,-1.2 15,-0.1 -2,-0.2 -0.971 86.5-111.5-141.0 160.0 -5.7 -19.0 11.0 99 101 A D T 3 S+ 0 0 64 -2,-0.3 48,-0.2 1,-0.3 14,-0.1 0.686 109.8 55.6 -65.9 -25.5 -9.1 -19.1 12.6 100 102 A G T 3 S+ 0 0 60 12,-0.1 2,-0.3 13,-0.1 -1,-0.3 -0.065 112.1 43.0 -98.3 26.7 -8.0 -19.5 16.2 101 103 A Q < + 0 0 54 -3,-1.2 -5,-0.6 12,-0.1 -3,-0.2 -0.941 66.0 91.4-164.6 147.7 -5.8 -16.5 16.1 102 104 A G + 0 0 1 1,-0.5 13,-0.3 -2,-0.3 11,-0.2 -0.014 59.3 103.2 151.2 -40.1 -6.3 -13.0 14.8 103 105 A S - 0 0 2 9,-2.7 -1,-0.5 11,-0.3 12,-0.1 -0.303 52.6-154.7 -68.8 158.0 -7.8 -10.9 17.7 104 106 A E S S+ 0 0 3 -10,-0.1 -1,-0.1 138,-0.1 141,-0.1 0.888 81.2 57.1-100.1 -50.5 -5.7 -8.4 19.7 105 107 A H S S- 0 0 0 -77,-0.1 7,-0.4 140,-0.1 2,-0.3 -0.272 75.1-159.6 -73.6 160.5 -7.8 -8.5 22.8 106 108 A T E -a 30 0A 9 -77,-1.1 -75,-3.1 5,-0.1 2,-0.5 -0.967 11.7-140.9-140.4 156.6 -8.3 -11.8 24.5 107 109 A V E > S-aB 31 110A 21 3,-1.9 3,-2.4 -2,-0.3 -75,-0.2 -0.979 88.3 -21.4-125.4 110.4 -10.9 -13.1 27.0 108 110 A D T 3 S- 0 0 74 -77,-3.3 -1,-0.2 -2,-0.5 -76,-0.1 0.906 129.1 -56.2 53.1 40.6 -9.6 -15.4 29.7 109 111 A K T 3 S+ 0 0 155 -78,-0.2 2,-0.3 1,-0.2 -1,-0.3 0.393 105.5 136.3 69.6 5.9 -6.8 -15.9 27.1 110 112 A K B < -B 107 0A 107 -3,-2.4 -3,-1.9 -9,-0.0 2,-0.4 -0.694 41.4-151.2 -84.2 135.7 -9.2 -17.0 24.3 111 113 A K - 0 0 90 -2,-0.3 2,-0.2 -11,-0.2 -5,-0.1 -0.865 4.0-149.1-108.4 145.1 -8.3 -15.5 20.9 112 114 A Y - 0 0 30 -7,-0.4 -9,-2.7 -2,-0.4 34,-0.2 -0.600 29.3-106.1-107.7 164.0 -10.9 -14.8 18.2 113 115 A A S S- 0 0 3 32,-1.2 -17,-1.0 -11,-0.2 2,-0.3 0.789 94.5 -3.7 -68.7 -25.7 -10.3 -14.8 14.5 114 116 A A E -IJ 95 145B 1 31,-1.3 31,-2.8 -19,-0.2 2,-0.4 -0.929 55.6-142.8-159.7 165.4 -10.5 -11.0 14.0 115 117 A E E -IJ 94 144B 0 -21,-1.7 -21,-1.2 -13,-0.3 2,-0.4 -0.969 16.4-150.2-140.7 111.9 -11.1 -7.9 16.0 116 118 A L E -IJ 93 143B 0 27,-2.7 27,-2.3 -2,-0.4 2,-0.5 -0.643 13.8-158.1 -77.1 132.8 -12.9 -5.0 14.3 117 119 A H E -IJ 92 142B 3 -25,-2.8 -25,-1.7 -2,-0.4 2,-0.6 -0.934 10.9-167.1-123.5 123.9 -11.9 -1.6 15.5 118 120 A L E -IJ 91 141B 0 23,-1.9 23,-2.7 -2,-0.5 2,-0.4 -0.947 18.1-153.5-102.7 117.0 -14.1 1.6 15.2 119 121 A V E +IJ 90 140B 6 -29,-2.7 -30,-3.2 -2,-0.6 -29,-1.0 -0.736 15.9 176.9-102.9 130.6 -12.0 4.7 16.0 120 122 A H E -IJ 88 139B 0 19,-1.5 19,-2.0 -2,-0.4 2,-0.3 -0.978 16.1-146.4-132.9 142.1 -13.4 8.0 17.3 121 123 A W E -IJ 87 138B 7 -34,-2.2 -34,-3.5 -2,-0.3 2,-0.5 -0.869 28.8-106.3-109.7 153.9 -11.8 11.3 18.3 122 124 A N E > -I 86 0B 2 15,-2.6 3,-2.0 -2,-0.3 -36,-0.2 -0.739 22.4-146.9 -78.8 114.9 -13.0 13.6 21.1 123 125 A T G > S+ 0 0 41 -38,-2.4 3,-2.4 -2,-0.5 -1,-0.1 0.663 90.0 80.3 -57.3 -27.1 -14.5 16.6 19.4 124 127 A K G 3 S+ 0 0 128 -39,-0.3 -1,-0.3 1,-0.3 -38,-0.1 0.730 89.3 57.6 -57.4 -21.9 -13.3 18.8 22.3 125 128 A Y G < S- 0 0 48 -3,-2.0 2,-1.1 12,-0.2 -1,-0.3 0.482 99.6-131.9 -94.0 5.1 -9.9 18.8 20.5 126 129 A G S < S+ 0 0 58 -3,-2.4 2,-0.3 4,-0.1 -3,-0.1 -0.129 78.6 23.1 77.3 -42.8 -10.9 20.2 17.1 127 130 A D S >> S- 0 0 72 -2,-1.1 4,-2.2 -5,-0.2 3,-1.0 -0.992 80.2-106.5-153.6 165.3 -9.1 17.5 15.0 128 131 A F H 3> S+ 0 0 68 -2,-0.3 4,-2.4 1,-0.3 -6,-0.1 0.850 115.1 55.1 -59.6 -45.3 -7.8 13.9 15.2 129 132 A G H 34 S+ 0 0 30 2,-0.2 4,-0.3 1,-0.2 -1,-0.3 0.702 111.4 45.9 -64.8 -19.6 -4.1 14.8 15.4 130 133 A K H X4 S+ 0 0 103 -3,-1.0 3,-1.3 2,-0.2 -2,-0.2 0.916 109.3 56.0 -86.4 -41.3 -4.8 17.0 18.4 131 134 A A H >< S+ 0 0 0 -4,-2.2 3,-1.6 1,-0.3 6,-0.3 0.824 98.4 61.6 -57.7 -47.2 -7.0 14.2 19.9 132 135 A V T 3< S+ 0 0 21 -4,-2.4 -1,-0.3 1,-0.3 -2,-0.2 0.678 96.8 60.1 -50.5 -26.0 -4.0 11.7 19.8 133 136 A Q T < S+ 0 0 139 -3,-1.3 -1,-0.3 -4,-0.3 -2,-0.1 0.032 94.5 80.7 -91.6 18.8 -1.9 13.9 22.1 134 137 A Q S X S- 0 0 72 -3,-1.6 3,-1.7 1,-0.1 4,-0.3 -0.975 79.0-128.2-133.0 145.5 -4.4 13.7 25.0 135 138 A P T 3 S+ 0 0 75 0, 0.0 3,-0.2 0, 0.0 -1,-0.1 0.725 116.6 32.7 -58.4 -32.1 -5.1 11.1 27.6 136 139 A D T 3 S+ 0 0 43 1,-0.1 -53,-0.1 -5,-0.1 67,-0.1 -0.011 88.0 119.8-117.1 28.7 -8.8 11.1 26.8 137 140 A G < + 0 0 0 -3,-1.7 -15,-2.6 -6,-0.3 2,-0.3 0.844 69.6 26.4 -57.3 -57.2 -8.2 11.8 23.1 138 141 A L E -Jk 121 204B 0 65,-3.2 67,-2.2 -4,-0.3 2,-0.4 -0.882 53.8-153.0-119.0 163.7 -9.8 8.8 21.5 139 142 A A E -Jk 120 205B 0 -19,-2.0 -19,-1.5 -2,-0.3 2,-0.6 -0.989 14.4-167.7-128.2 120.0 -12.5 6.1 22.0 140 143 A V E -Jk 119 206B 2 65,-1.9 67,-2.3 -2,-0.4 2,-0.6 -0.903 7.4-157.0-115.1 116.6 -12.0 2.7 20.3 141 144 A L E -Jk 118 207B 0 -23,-2.7 -23,-1.9 -2,-0.6 2,-0.5 -0.763 17.2-158.5 -88.0 130.6 -15.0 0.4 20.3 142 145 A G E -Jk 117 208B 0 65,-3.2 67,-2.6 -2,-0.6 2,-0.4 -0.837 12.0-175.9-111.6 140.5 -13.7 -3.2 19.8 143 146 A I E -J 116 0B 0 -27,-2.3 -27,-2.7 -2,-0.5 2,-0.2 -0.979 19.1-133.3-134.1 130.9 -15.7 -6.2 18.5 144 147 A F E -J 115 0B 0 -2,-0.4 69,-2.6 65,-0.4 2,-0.5 -0.520 12.7-145.1 -80.5 154.0 -14.5 -9.8 18.2 145 148 A L E -Jl 114 213B 1 -31,-2.8 -31,-1.3 67,-0.2 -32,-1.2 -0.984 13.7-171.3-119.2 123.8 -15.1 -11.8 15.1 146 149 A K E - l 0 214B 86 67,-2.6 69,-2.8 -2,-0.5 2,-0.6 -0.865 29.9-115.0-109.0 145.3 -15.8 -15.5 15.4 147 150 A V E S+ l 0 215B 48 -2,-0.4 69,-0.2 -48,-0.2 2,-0.2 -0.689 74.9 95.5 -80.8 120.8 -16.0 -17.8 12.3 148 151 A G S S+ 0 0 38 67,-3.6 69,-0.5 -2,-0.6 2,-0.2 -0.462 74.2 11.4-161.6-123.1 -19.5 -19.1 12.0 149 152 A S S S- 0 0 87 -2,-0.2 -1,-0.3 1,-0.2 -3,-0.1 -0.479 84.4 -97.1 -71.4 147.2 -22.5 -17.9 10.0 150 153 A A - 0 0 61 65,-0.3 -1,-0.2 -2,-0.2 64,-0.1 -0.098 28.5-134.4 -62.4 163.8 -21.9 -15.3 7.3 151 154 A K >> - 0 0 50 1,-0.2 3,-2.2 62,-0.1 4,-0.8 -0.926 9.4-162.3-129.8 103.8 -22.5 -11.5 8.1 152 155 A P G >4 S+ 0 0 113 0, 0.0 3,-1.4 0, 0.0 4,-0.4 0.879 88.9 60.8 -45.8 -51.2 -24.5 -9.8 5.3 153 156 A G G 34 S+ 0 0 25 27,-0.3 27,-0.2 1,-0.3 4,-0.1 0.414 103.0 49.0 -56.5 -15.6 -23.5 -6.5 6.6 154 157 A L G X> S+ 0 0 1 -3,-2.2 4,-1.4 2,-0.1 3,-1.1 0.637 88.3 86.2-102.9 -15.6 -19.8 -7.1 6.0 155 158 A Q H S+ 0 0 107 -4,-0.4 4,-0.6 1,-0.2 -1,-0.3 0.883 109.5 48.5 -64.1 -30.2 -19.9 -5.0 0.7 157 160 A V H X> S+ 0 0 0 -3,-1.1 3,-1.1 2,-0.2 4,-0.8 0.941 109.9 49.7 -69.9 -47.9 -16.5 -4.7 2.4 158 161 A V H 3< S+ 0 0 3 -4,-1.4 3,-0.5 1,-0.3 4,-0.4 0.835 105.9 59.0 -56.3 -45.7 -15.3 -8.2 1.3 159 162 A D H 3< S+ 0 0 95 -4,-2.3 -1,-0.3 1,-0.2 3,-0.2 0.654 104.1 46.6 -61.1 -26.7 -16.3 -7.5 -2.2 160 163 A V H X< S+ 0 0 28 -3,-1.1 3,-2.4 -4,-0.6 4,-0.5 0.543 83.7 92.7 -97.1 -9.8 -14.1 -4.4 -2.8 161 164 A L G >< S+ 0 0 7 -4,-0.8 3,-2.1 -3,-0.5 -1,-0.2 0.887 75.9 67.4 -49.5 -39.1 -11.0 -6.0 -1.3 162 165 A D G > S+ 0 0 136 -4,-0.4 3,-0.6 1,-0.3 -1,-0.3 0.782 99.3 50.7 -51.7 -31.2 -10.0 -7.1 -4.8 163 166 A S G < S+ 0 0 61 -3,-2.4 -1,-0.3 1,-0.2 -2,-0.2 0.502 112.1 43.4 -88.0 -5.7 -9.5 -3.4 -5.8 164 167 A I G < S+ 0 0 0 -3,-2.1 -1,-0.2 -4,-0.5 63,-0.2 -0.218 71.8 139.1-128.3 38.5 -7.2 -2.4 -2.9 165 168 A K < + 0 0 70 -3,-0.6 62,-2.7 61,-0.1 2,-0.3 0.846 59.9 45.8 -53.0 -45.0 -5.0 -5.5 -3.0 166 169 A T S > S- 0 0 14 60,-0.2 3,-2.3 1,-0.1 -107,-0.3 -0.710 98.3 -76.3-111.7 161.6 -1.7 -3.7 -2.4 167 170 A K B 3 S+o 230 0C 100 62,-2.2 64,-0.5 1,-0.3 -107,-0.2 -0.170 114.4 21.7 -53.6 127.3 -0.3 -1.0 -0.2 168 171 A G T 3 S+ 0 0 54 -109,-2.0 -1,-0.3 1,-0.4 2,-0.1 0.107 88.8 128.5 97.5 -16.2 -1.3 2.4 -1.2 169 172 A K < + 0 0 76 -3,-2.3 -110,-2.9 -5,-0.1 -1,-0.4 -0.410 31.3 178.3 -71.3 148.5 -4.4 1.5 -3.1 170 173 A S E -F 58 0B 58 -112,-0.3 2,-0.3 -7,-0.2 -112,-0.2 -0.896 9.0-166.7-139.0 164.1 -7.7 3.2 -2.3 171 174 A A E -F 57 0B 21 -114,-2.1 -114,-2.7 -2,-0.3 -116,-0.1 -0.953 36.4 -94.8-154.5 144.8 -11.2 3.0 -3.8 172 175 A D E -F 56 0B 146 -2,-0.3 -116,-0.3 -116,-0.2 2,-0.1 -0.339 42.7-179.3 -58.9 140.5 -14.4 5.2 -3.4 173 176 A F + 0 0 18 -118,-3.5 3,-0.4 -106,-0.1 2,-0.2 -0.498 13.0 158.8-148.7 73.9 -16.5 3.6 -0.7 174 177 A T + 0 0 77 1,-0.2 -119,-0.2 -119,-0.1 -121,-0.1 -0.570 52.2 26.2 -99.0 161.3 -19.7 5.5 -0.1 175 178 A N S S+ 0 0 134 -121,-0.6 2,-0.4 1,-0.2 -1,-0.2 0.668 73.4 145.6 64.8 21.9 -23.0 4.6 1.5 176 179 A F - 0 0 9 -3,-0.4 -1,-0.2 -20,-0.0 -122,-0.2 -0.724 37.6-150.5 -87.3 138.7 -21.6 1.9 3.8 177 180 A D > - 0 0 61 -2,-0.4 3,-1.6 1,-0.1 -127,-0.1 -0.901 7.4-158.5-110.3 119.0 -23.5 1.8 7.1 178 181 A P G > S+ 0 0 0 0, 0.0 3,-1.5 0, 0.0 4,-0.1 0.481 81.1 86.2 -78.4 5.8 -21.4 0.6 10.1 179 182 A R G > S+ 0 0 127 1,-0.3 3,-1.0 -130,-0.2 -26,-0.1 0.721 76.6 68.0 -72.7 -22.2 -24.6 -0.4 11.9 180 183 A G G < S+ 0 0 29 -3,-1.6 -27,-0.3 1,-0.2 -1,-0.3 0.597 94.7 59.1 -72.8 -6.9 -24.4 -3.7 10.1 181 184 A L G < S+ 0 0 0 -3,-1.5 -1,-0.2 -28,-0.1 -2,-0.2 0.411 82.0 102.2-100.4 -3.8 -21.2 -4.5 12.2 182 185 A L < - 0 0 32 -3,-1.0 4,-0.1 -4,-0.1 -39,-0.0 -0.649 67.8-127.3 -87.9 137.8 -22.7 -4.3 15.7 183 186 A P - 0 0 8 0, 0.0 30,-0.1 0, 0.0 -1,-0.1 -0.275 32.3-104.4 -74.2 165.5 -23.6 -7.2 17.8 184 187 A E S S+ 0 0 189 2,-0.0 2,-0.3 -2,-0.0 -2,-0.0 0.912 104.6 53.4 -54.6 -47.5 -27.2 -7.4 19.3 185 188 A S - 0 0 28 1,-0.1 26,-0.2 2,-0.1 24,-0.0 -0.721 61.4-160.5 -95.6 140.0 -25.8 -6.5 22.8 186 189 A L + 0 0 60 -2,-0.3 -141,-0.3 23,-0.1 2,-0.1 0.067 43.5 135.3-108.8 20.7 -23.7 -3.5 23.8 187 190 A D + 0 0 57 -143,-0.1 23,-3.4 22,-0.1 24,-0.4 -0.472 34.3 168.2 -69.9 143.2 -22.3 -4.8 27.1 188 191 A Y E -M 209 0B 1 21,-0.3 68,-1.7 -2,-0.1 2,-0.3 -0.973 40.2-121.5-152.1 172.0 -18.7 -4.1 27.4 189 192 A W E -MN 208 255B 14 19,-2.0 19,-2.3 -2,-0.3 2,-0.3 -0.731 30.5-162.2-110.4 149.3 -15.4 -3.9 29.3 190 193 A T E +MN 207 254B 9 64,-2.4 64,-3.2 -2,-0.3 17,-0.2 -0.971 18.3 153.7-138.0 143.4 -13.5 -0.6 29.5 191 194 A Y E -M 206 0B 5 15,-1.1 15,-2.9 -2,-0.3 2,-0.5 -0.881 45.9-100.2-161.0 157.5 -9.9 0.3 30.4 192 195 A P E +M 205 0B 53 0, 0.0 13,-0.2 0, 0.0 2,-0.1 -0.740 61.2 133.9 -86.0 123.4 -7.5 3.1 29.6 193 196 A G E -M 204 0B 0 11,-3.6 11,-1.3 -2,-0.5 2,-0.2 -0.364 40.8 -99.2-145.5-147.7 -5.1 2.1 26.9 194 197 A S - 0 0 0 8,-0.2 8,-0.2 9,-0.2 2,-0.2 -0.793 43.5 -71.4-143.6 173.7 -3.3 3.0 23.7 195 198 A L - 0 0 30 6,-1.7 -168,-0.4 -2,-0.2 9,-0.1 -0.550 39.6-140.2 -68.1 151.9 -3.2 2.6 19.8 196 199 A T S S+ 0 0 6 -2,-0.2 -1,-0.1 2,-0.1 -170,-0.0 0.548 84.2 53.3 -99.0 -5.5 -2.1 -0.9 19.0 197 200 A T S > S- 0 0 25 1,-0.1 3,-2.0 4,-0.1 4,-0.2 -0.843 104.9 -47.5-119.8 154.4 0.1 0.1 16.1 198 201 A P T 3 S+ 0 0 11 0, 0.0 -2,-0.1 0, 0.0 -1,-0.1 -0.228 123.8 46.0 -52.1 149.0 2.9 2.7 16.3 199 202 A P T 3 S- 0 0 63 0, 0.0 -179,-0.1 0, 0.0 -3,-0.0 -0.964 83.4-164.4 -73.3 12.2 3.0 5.5 17.4 200 203 A L < - 0 0 0 -3,-2.0 2,-0.1 1,-0.2 -173,-0.1 0.784 17.4-174.6 47.6 38.3 1.2 3.5 20.1 201 204 A L - 0 0 52 -4,-0.2 -6,-1.7 -7,-0.1 2,-1.7 -0.368 29.8-129.0 -66.0 143.3 0.0 6.7 21.9 202 205 A E S S+ 0 0 49 -8,-0.2 -8,-0.2 1,-0.2 -1,-0.1 -0.531 74.8 112.1 -92.9 70.4 -1.7 6.3 25.2 203 206 A C + 0 0 1 -2,-1.7 -65,-3.2 -67,-0.1 2,-0.4 0.145 48.8 108.4-123.8 8.0 -4.7 8.3 24.2 204 207 A V E -kM 138 193B 0 -11,-1.3 -11,-3.6 -3,-0.3 2,-0.7 -0.821 48.6-164.1-107.1 141.8 -7.4 5.7 24.1 205 208 A T E -kM 139 192B 26 -67,-2.2 -65,-1.9 -2,-0.4 2,-0.3 -0.976 33.3-145.7-103.0 111.5 -10.3 4.7 26.3 206 209 A W E -kM 140 191B 4 -15,-2.9 -15,-1.1 -2,-0.7 2,-0.4 -0.634 19.0-172.7 -88.2 139.4 -11.0 1.2 25.1 207 210 A I E -kM 141 190B 0 -67,-2.3 -65,-3.2 -2,-0.3 2,-0.5 -0.900 9.5-172.0-130.7 105.6 -14.6 -0.1 25.0 208 211 A V E -kM 142 189B 0 -19,-2.3 -19,-2.0 -2,-0.4 2,-0.2 -0.945 22.1-126.8-108.3 115.5 -14.6 -3.9 24.1 209 212 A L E - M 0 188B 0 -67,-2.6 -65,-0.4 -2,-0.5 -21,-0.3 -0.337 6.4-142.4 -70.6 128.7 -18.0 -5.5 23.4 210 213 A K S S+ 0 0 63 -23,-3.4 -1,-0.1 -2,-0.2 -22,-0.1 0.980 85.0 60.1 -52.1 -58.0 -18.8 -8.6 25.4 211 214 A E S S- 0 0 56 -24,-0.4 -67,-0.2 -26,-0.2 -2,-0.1 -0.581 74.6-149.2 -81.8 134.0 -20.5 -10.3 22.5 212 215 A P - 0 0 33 0, 0.0 2,-0.3 0, 0.0 -67,-0.2 -0.338 12.6-127.0 -90.6 177.3 -18.7 -11.1 19.2 213 216 A I E -l 145 0B 9 -69,-2.6 -67,-2.6 -30,-0.1 2,-0.3 -0.867 23.8-113.3-119.8 161.9 -20.3 -11.3 15.8 214 217 A S E -l 146 0B 30 -2,-0.3 2,-0.3 -69,-0.2 -67,-0.2 -0.718 27.6-179.3 -95.6 146.9 -20.1 -14.1 13.3 215 218 A V E -l 147 0B 3 -69,-2.8 -67,-3.6 -2,-0.3 -65,-0.3 -0.976 29.8-114.2-134.9 149.2 -18.3 -14.2 9.9 216 219 A S > - 0 0 9 -2,-0.3 4,-2.2 -69,-0.2 5,-0.2 -0.435 27.4-113.9 -81.5 161.3 -18.2 -17.1 7.5 217 220 A S H > S+ 0 0 47 -69,-0.5 4,-2.5 1,-0.2 -1,-0.1 0.918 118.4 56.0 -52.0 -44.0 -14.9 -18.8 6.8 218 221 A E H > S+ 0 0 124 2,-0.2 4,-1.7 1,-0.2 -1,-0.2 0.880 104.0 51.6 -58.9 -42.8 -15.2 -17.5 3.2 219 222 A Q H > S+ 0 0 3 1,-0.2 4,-0.6 2,-0.2 3,-0.3 0.958 112.5 46.2 -61.6 -48.2 -15.5 -13.9 4.4 220 223 A V H >X S+ 0 0 4 -4,-2.2 4,-1.3 1,-0.2 3,-1.0 0.821 104.8 63.0 -61.6 -38.9 -12.4 -14.2 6.5 221 224 A L H >X S+ 0 0 81 -4,-2.5 3,-0.8 1,-0.3 4,-0.5 0.925 96.8 55.8 -51.4 -51.2 -10.6 -15.9 3.6 222 225 A K H 3< S+ 0 0 84 -4,-1.7 3,-0.5 -3,-0.3 -1,-0.3 0.693 102.3 56.9 -57.6 -18.8 -10.8 -12.8 1.5 223 226 A F H X< S+ 0 0 3 -3,-1.0 3,-1.7 -4,-0.6 -1,-0.3 0.890 101.5 58.2 -72.3 -43.4 -9.1 -10.7 4.2 224 227 A R H << S+ 0 0 33 -4,-1.3 -1,-0.2 -3,-0.8 -2,-0.2 0.576 95.4 65.9 -60.6 -13.8 -6.2 -13.2 4.0 225 228 A K T 3< S+ 0 0 127 -4,-0.5 -1,-0.3 -3,-0.5 -2,-0.2 0.511 78.2 100.1 -91.8 -7.0 -5.8 -12.3 0.3 226 229 A L < - 0 0 3 -3,-1.7 12,-3.8 12,-0.3 2,-0.3 -0.408 67.2-130.4 -75.1 167.0 -4.7 -8.8 0.8 227 230 A N B -P 237 0D 8 -62,-2.7 -166,-0.2 10,-0.3 10,-0.2 -0.897 15.7-154.4-120.0 153.6 -1.0 -7.9 0.6 228 231 A F S S+ 0 0 31 8,-1.9 9,-0.1 -2,-0.3 -1,-0.1 0.735 80.3 80.4 -81.5 -42.8 1.3 -5.9 2.9 229 232 A N S S- 0 0 3 7,-0.6 -62,-2.2 5,-0.1 2,-0.2 -0.221 85.0-112.3 -72.1 158.4 3.5 -5.1 -0.1 230 233 A G B > -o 167 0C 7 -64,-0.3 3,-1.6 1,-0.1 -62,-0.1 -0.559 50.8 -74.8 -87.1 157.2 2.9 -2.4 -2.8 231 234 A E T 3 S+ 0 0 138 -64,-0.5 -1,-0.1 1,-0.3 0, 0.0 -0.263 122.1 27.2 -57.0 134.5 2.1 -3.3 -6.4 232 235 A G T 3 S+ 0 0 85 1,-0.4 -1,-0.3 -3,-0.1 3,-0.0 0.497 100.9 105.2 86.0 7.2 5.2 -4.5 -8.3 233 236 A E S < S- 0 0 107 -3,-1.6 -1,-0.4 1,-0.1 3,-0.1 -0.784 86.8 -81.8-112.0 157.9 6.8 -5.8 -5.1 234 237 A P - 0 0 112 0, 0.0 2,-0.2 0, 0.0 -5,-0.1 -0.344 59.8 -93.8 -61.7 141.5 7.1 -9.5 -4.1 235 238 A E + 0 0 124 -7,-0.1 2,-0.4 -8,-0.1 -8,-0.0 -0.397 43.6 173.9 -67.3 126.7 3.9 -10.8 -2.5 236 239 A E - 0 0 101 -2,-0.2 -8,-1.9 -3,-0.1 -7,-0.6 -0.991 31.9-129.4-128.9 111.7 3.6 -10.8 1.3 237 240 A L B -P 227 0D 89 -2,-0.4 2,-1.1 -10,-0.2 -10,-0.3 -0.486 19.2-118.8 -71.1 140.2 0.1 -11.8 2.4 238 241 A M + 0 0 0 -12,-3.8 -12,-0.3 -15,-0.2 2,-0.3 -0.700 65.1 125.5 -79.8 101.4 -1.6 -9.4 4.9 239 242 A V + 0 0 32 -2,-1.1 -143,-0.2 1,-0.1 -142,-0.1 -0.992 51.1 29.6-155.5 156.9 -2.1 -11.7 7.9 240 243 A D + 0 0 41 -145,-0.9 2,-0.6 -2,-0.3 -144,-0.2 0.920 64.0 156.7 56.8 37.5 -1.3 -11.9 11.6 241 244 A N + 0 0 0 -146,-1.3 2,-0.3 -3,-0.1 -1,-0.2 -0.399 35.9 113.7 -91.1 46.0 -1.4 -8.1 11.7 242 245 A W - 0 0 53 -2,-0.6 -139,-0.1 -148,-0.1 -138,-0.1 -0.888 62.6-133.6-124.2 142.8 -2.2 -8.3 15.5 243 246 A R - 0 0 6 -2,-0.3 3,-0.1 -233,-0.1 2,-0.1 -0.790 31.1-112.1 -90.6 151.3 -0.1 -7.2 18.4 244 247 A P - 0 0 61 0, 0.0 -140,-0.1 0, 0.0 -139,-0.1 -0.377 45.8 -75.5 -77.8 160.2 0.2 -9.6 21.4 245 248 A A - 0 0 48 -141,-0.1 -216,-0.3 -216,-0.1 -218,-0.1 -0.027 48.7-142.6 -55.4 141.3 -1.3 -9.0 24.8 246 249 A Q - 0 0 42 -218,-2.2 -216,-0.5 -220,-0.2 -1,-0.1 -0.856 26.2 -90.1-113.0 152.7 0.5 -6.4 27.0 247 250 A P - 0 0 75 0, 0.0 -221,-0.2 0, 0.0 -1,-0.0 -0.330 29.6-144.5 -61.5 134.8 1.0 -6.4 30.8 248 251 A L + 0 0 52 1,-0.2 3,-0.2 -223,-0.1 -219,-0.0 0.799 35.3 165.0 -70.0 -39.3 -1.8 -4.6 32.5 249 252 A K + 0 0 96 1,-0.2 2,-1.5 -224,-0.0 -1,-0.2 -0.195 66.1 5.2 57.6-130.1 0.3 -3.0 35.3 250 253 A N S S+ 0 0 162 -226,-0.2 2,-0.3 2,-0.0 -1,-0.2 -0.157 108.8 102.7 -83.9 48.7 -1.4 -0.2 37.2 251 254 A R - 0 0 32 -2,-1.5 2,-0.3 -3,-0.2 -3,-0.1 -0.919 53.4-148.6-135.1 156.3 -4.9 -0.6 35.6 252 255 A Q - 0 0 101 -2,-0.3 2,-0.5 -216,-0.0 -216,-0.1 -0.896 13.8-140.1-119.4 138.3 -8.3 -2.0 36.3 253 256 A I - 0 0 12 -2,-0.3 -216,-2.5 -218,-0.2 2,-0.4 -0.898 21.8-158.8 -99.3 133.0 -10.8 -3.4 33.7 254 257 A K E -cN 37 190B 54 -64,-3.2 -64,-2.4 -2,-0.5 2,-0.3 -0.922 0.9-150.8-118.2 140.8 -14.4 -2.4 34.4 255 258 A A E -cN 38 189B 5 -218,-2.4 -216,-2.4 -2,-0.4 -66,-0.2 -0.727 14.4-150.6-104.9 157.6 -17.5 -4.1 33.2 256 259 A S S S+ 0 0 26 -68,-1.7 2,-0.3 -2,-0.3 -67,-0.1 0.380 82.5 49.7-107.2 6.1 -20.9 -2.7 32.4 257 260 A F 0 0 44 -69,-0.2 -2,-0.1 1,-0.1 -218,-0.1 -0.898 360.0 360.0-139.4 163.6 -22.6 -5.9 33.3 258 261 A K 0 0 222 -2,-0.3 -1,-0.1 -220,-0.1 -220,-0.1 0.768 360.0 360.0-111.2 360.0 -22.7 -8.6 36.0