==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=11-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSFERASE 06-NOV-03 1RE8 . COMPND 2 MOLECULE: CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC . SOURCE 2 ORGANISM_SCIENTIFIC: MUS MUSCULUS; . AUTHOR P.AKAMINE,MADHUSUDAN,L.L.BRUNTON,H.D.OU,J.M.CANAVES, . 339 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 15670.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 221 65.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 45 13.3 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 26 7.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 40 11.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 95 28.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 4 1.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 1 1 0 1 1 1 0 0 1 0 0 1 0 0 1 1 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 1 1 0 1 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 12 A Q > 0 0 152 0, 0.0 4,-1.9 0, 0.0 3,-0.3 0.000 360.0 360.0 360.0 86.1 16.9 62.0 46.1 2 13 A E H > + 0 0 160 1,-0.2 4,-2.3 2,-0.2 5,-0.3 0.737 360.0 56.7 -65.9 -40.3 20.3 63.0 44.5 3 14 A S H > S+ 0 0 100 1,-0.2 4,-0.7 2,-0.2 -1,-0.2 0.836 116.1 39.3 -65.7 -34.3 21.8 59.8 43.3 4 15 A V H > S+ 0 0 39 -3,-0.3 4,-2.8 2,-0.2 -2,-0.2 0.850 114.1 54.9 -82.5 -38.6 18.8 59.0 41.1 5 16 A K H X S+ 0 0 57 -4,-1.9 4,-1.9 2,-0.2 -2,-0.2 0.946 111.8 41.3 -63.6 -49.0 18.3 62.7 40.1 6 17 A E H X S+ 0 0 66 -4,-2.3 4,-2.4 2,-0.2 -1,-0.2 0.856 115.1 54.4 -65.9 -31.4 21.8 63.2 38.7 7 18 A F H X S+ 0 0 78 -4,-0.7 4,-1.8 -5,-0.3 -2,-0.2 0.956 111.3 42.8 -64.3 -51.6 21.5 59.7 37.1 8 19 A L H X S+ 0 0 34 -4,-2.8 4,-1.7 2,-0.2 -2,-0.2 0.778 111.1 57.4 -68.5 -26.0 18.3 60.6 35.3 9 20 A A H X S+ 0 0 57 -4,-1.9 4,-1.8 2,-0.2 3,-0.3 0.956 108.3 44.4 -69.1 -49.6 19.7 64.0 34.3 10 21 A K H X S+ 0 0 37 -4,-2.4 4,-2.2 1,-0.2 -2,-0.2 0.875 112.4 57.3 -62.4 -28.9 22.7 62.3 32.5 11 22 A A H X S+ 0 0 11 -4,-1.8 4,-2.0 2,-0.2 -1,-0.2 0.860 105.9 45.4 -70.7 -37.0 20.2 59.9 31.0 12 23 A K H X S+ 0 0 69 -4,-1.7 4,-3.0 -3,-0.3 5,-0.2 0.907 114.1 49.1 -75.1 -36.7 17.9 62.5 29.3 13 24 A E H X S+ 0 0 128 -4,-1.8 4,-1.6 2,-0.2 -2,-0.2 0.903 112.7 47.4 -69.0 -37.9 20.9 64.4 27.9 14 25 A D H X S+ 0 0 96 -4,-2.2 4,-1.1 -5,-0.2 -2,-0.2 0.929 115.4 47.1 -64.8 -43.1 22.5 61.2 26.5 15 26 A F H >X S+ 0 0 2 -4,-2.0 4,-2.7 1,-0.2 3,-0.7 0.941 110.3 49.9 -61.6 -53.8 19.1 60.2 25.1 16 27 A L H 3X S+ 0 0 40 -4,-3.0 4,-2.7 1,-0.2 5,-0.2 0.797 102.6 61.6 -61.7 -29.3 18.3 63.6 23.5 17 28 A K H 3X S+ 0 0 149 -4,-1.6 4,-0.6 1,-0.2 -1,-0.2 0.902 115.1 34.8 -59.6 -41.1 21.7 63.7 21.8 18 29 A K H << S+ 0 0 108 -4,-1.1 -2,-0.2 -3,-0.7 -1,-0.2 0.836 116.5 55.3 -78.5 -38.0 20.7 60.6 19.9 19 30 A W H < S+ 0 0 26 -4,-2.7 -2,-0.2 1,-0.2 -3,-0.2 0.897 109.4 45.4 -63.7 -44.1 17.0 61.5 19.6 20 31 A E H < S+ 0 0 125 -4,-2.7 -1,-0.2 1,-0.3 -2,-0.2 0.696 125.0 30.6 -78.1 -22.6 17.7 64.9 17.9 21 32 A T S < S- 0 0 113 -4,-0.6 -1,-0.3 -5,-0.2 -2,-0.1 -0.687 86.3-163.9-136.4 84.0 20.2 63.5 15.4 22 33 A P - 0 0 44 0, 0.0 2,-0.4 0, 0.0 -3,-0.1 -0.236 20.4-114.5 -68.3 152.2 19.4 59.8 14.6 23 34 A S - 0 0 52 59,-0.1 2,-0.3 -5,-0.1 3,-0.1 -0.722 36.6-177.0 -86.0 134.5 21.6 57.3 13.0 24 35 A Q + 0 0 99 -2,-0.4 75,-0.1 1,-0.2 315,-0.1 -0.930 53.7 8.6-129.1 152.2 20.5 56.1 9.6 25 36 A N + 0 0 121 -2,-0.3 74,-0.2 1,-0.1 -1,-0.2 0.861 63.5 153.5 47.2 60.1 21.9 53.5 7.2 26 37 A T + 0 0 67 72,-2.5 2,-0.3 -3,-0.1 73,-0.2 0.451 63.1 10.7 -96.9 -2.0 24.6 51.8 9.3 27 38 A A - 0 0 9 71,-0.5 2,-0.3 70,-0.0 3,-0.0 -0.945 65.3-125.3-160.7 176.7 24.6 48.4 7.5 28 39 A Q > - 0 0 104 -2,-0.3 3,-1.1 71,-0.1 73,-0.1 -0.929 24.7-119.5-130.4 155.9 23.3 46.4 4.5 29 40 A L G > S+ 0 0 47 -2,-0.3 3,-1.5 1,-0.2 -1,-0.1 0.847 108.1 61.7 -65.7 -36.2 21.4 43.1 4.2 30 41 A D G 3 S+ 0 0 105 1,-0.3 -1,-0.2 3,-0.0 3,-0.0 0.316 89.0 70.9 -77.6 9.7 24.1 41.3 2.2 31 42 A Q G < S+ 0 0 66 -3,-1.1 21,-2.2 21,-0.1 22,-0.4 0.311 96.6 66.9 -97.5 4.4 26.5 41.6 5.2 32 43 A F E < S-A 51 0A 14 -3,-1.5 2,-0.5 19,-0.3 19,-0.2 -0.951 71.4-141.9-128.9 144.4 24.4 39.1 7.0 33 44 A D E -A 50 0A 78 17,-2.9 17,-2.6 -2,-0.3 2,-0.3 -0.926 26.5-125.2-102.5 131.7 23.6 35.4 6.6 34 45 A R E +A 49 0A 87 -2,-0.5 15,-0.2 15,-0.2 3,-0.1 -0.580 36.4 163.4 -76.9 131.2 20.0 34.3 7.4 35 46 A I E - 0 0 83 13,-2.7 2,-0.3 -2,-0.3 14,-0.2 0.787 53.9 -24.5-112.6 -61.0 19.6 31.5 9.9 36 47 A K E -A 48 0A 32 12,-1.1 12,-3.3 282,-0.0 2,-0.4 -0.995 54.8-105.9-160.0 147.7 16.1 31.1 11.4 37 48 A T E -A 47 0A 2 282,-0.3 282,-0.4 -2,-0.3 10,-0.3 -0.658 28.7-179.0 -78.4 131.0 12.8 33.0 12.1 38 49 A L E - 0 0 7 8,-2.7 279,-0.3 -2,-0.4 2,-0.3 0.529 62.5 -14.9-105.9 -12.9 12.4 33.8 15.8 39 50 A G E -A 46 0A 11 7,-1.2 7,-2.2 277,-0.1 -1,-0.3 -0.951 56.2-136.7 178.7 160.3 9.1 35.6 15.7 40 51 A T E +A 45 0A 92 -2,-0.3 5,-0.3 5,-0.3 2,-0.2 -0.922 16.0 177.5-130.9 160.3 6.4 37.3 13.6 41 52 A G E > -A 44 0A 52 3,-2.5 3,-0.6 -2,-0.3 -2,-0.0 -0.852 49.7 -73.8-146.5-176.3 4.2 40.4 13.7 42 53 A S T 3 S+ 0 0 111 -2,-0.2 3,-0.0 1,-0.2 21,-0.0 0.843 126.7 20.0 -51.5 -45.4 1.7 42.3 11.6 43 54 A F T 3 S- 0 0 37 25,-0.0 21,-3.2 23,-0.0 2,-0.3 0.221 130.1 -27.9-115.0 10.3 4.1 43.7 9.0 44 55 A G E < -AB 41 63A 19 -3,-0.6 -3,-2.5 19,-0.2 2,-0.3 -0.897 60.5 -95.0 179.1-147.3 7.1 41.4 9.3 45 56 A R E -AB 40 62A 31 17,-1.8 17,-3.2 -2,-0.3 2,-0.5 -0.985 20.9-116.7-160.5 159.9 9.3 39.1 11.4 46 57 A V E -AB 39 61A 35 -7,-2.2 -8,-2.7 -2,-0.3 -7,-1.2 -0.925 35.5-170.8-106.5 136.7 12.4 38.9 13.5 47 58 A M E -AB 37 60A 0 13,-2.7 13,-3.8 -2,-0.5 2,-0.5 -0.974 26.2-123.2-132.5 139.5 15.2 36.7 12.2 48 59 A L E +AB 36 59A 1 -12,-3.3 -13,-2.7 -2,-0.4 -12,-1.1 -0.682 42.1 174.2 -78.5 125.7 18.4 35.3 13.6 49 60 A V E -AB 34 58A 4 9,-3.2 9,-2.6 -2,-0.5 2,-0.4 -0.876 25.7-135.9-128.1 163.9 21.2 36.4 11.2 50 61 A K E -AB 33 57A 72 -17,-2.6 -17,-2.9 -2,-0.3 2,-0.5 -0.988 19.6-126.4-126.4 125.9 24.9 36.1 11.3 51 62 A H E > -A 32 0A 26 5,-3.0 4,-2.1 -2,-0.4 -19,-0.3 -0.589 21.2-144.2 -71.3 120.8 27.2 39.0 10.4 52 63 A K T 4 S+ 0 0 112 -21,-2.2 -1,-0.1 -2,-0.5 -20,-0.1 0.770 89.0 36.7 -60.3 -37.6 29.6 37.6 7.7 53 64 A E T 4 S+ 0 0 188 -22,-0.4 -1,-0.2 1,-0.1 -21,-0.1 0.916 127.2 31.5 -84.6 -47.6 32.8 39.4 8.6 54 65 A S T 4 S- 0 0 64 2,-0.1 -2,-0.2 1,-0.0 -1,-0.1 0.700 94.9-135.2 -81.9 -23.0 32.7 39.5 12.4 55 66 A G < + 0 0 30 -4,-2.1 -3,-0.1 1,-0.2 2,-0.1 0.490 52.1 148.7 80.5 2.3 30.8 36.2 12.8 56 67 A N - 0 0 79 -5,-0.1 -5,-3.0 -6,-0.1 2,-0.3 -0.365 46.0-124.0 -71.6 148.4 28.5 37.8 15.4 57 68 A H E +B 50 0A 54 -7,-0.2 54,-0.6 54,-0.1 2,-0.3 -0.725 33.5 176.6 -90.1 139.1 24.8 36.7 15.8 58 69 A Y E -BC 49 110A 25 -9,-2.6 -9,-3.2 -2,-0.3 2,-0.6 -0.980 32.4-126.0-140.6 155.3 22.1 39.3 15.6 59 70 A A E -BC 48 109A 7 50,-2.0 50,-2.7 -2,-0.3 2,-0.6 -0.911 29.2-161.2 -98.1 116.3 18.3 39.5 15.6 60 71 A M E -BC 47 108A 0 -13,-3.8 -13,-2.7 -2,-0.6 2,-0.6 -0.904 5.3-155.5-106.4 118.2 17.1 41.3 12.5 61 72 A K E -BC 46 107A 25 46,-3.3 46,-2.0 -2,-0.6 2,-0.5 -0.827 12.5-165.3 -89.7 121.9 13.6 42.7 12.5 62 73 A I E -BC 45 106A 5 -17,-3.2 -17,-1.8 -2,-0.6 2,-0.4 -0.951 5.5-173.8-114.7 119.3 12.3 43.0 8.9 63 74 A L E -BC 44 105A 11 42,-2.7 42,-2.3 -2,-0.5 2,-0.6 -0.951 24.0-127.5-116.5 130.7 9.2 45.1 8.2 64 75 A D E >> - C 0 104A 56 -21,-3.2 4,-1.4 -2,-0.4 3,-0.6 -0.658 14.2-150.8 -79.0 115.2 7.4 45.3 4.8 65 76 A K H 3> S+ 0 0 2 38,-2.6 4,-1.8 -2,-0.6 -1,-0.1 0.827 92.6 49.1 -54.1 -40.4 7.0 49.0 3.8 66 77 A Q H 3> S+ 0 0 90 37,-0.4 4,-2.1 1,-0.2 -1,-0.2 0.817 107.3 53.9 -72.8 -30.0 3.8 48.6 1.8 67 78 A K H <> S+ 0 0 30 -3,-0.6 4,-1.5 2,-0.2 -1,-0.2 0.809 109.3 50.7 -73.1 -26.3 2.0 46.5 4.4 68 79 A V H <>S+ 0 0 0 -4,-1.4 5,-1.1 2,-0.2 6,-0.2 0.933 111.4 46.1 -72.4 -48.6 2.7 49.4 6.9 69 80 A V H ><5S+ 0 0 43 -4,-1.8 3,-0.9 3,-0.2 -2,-0.2 0.913 109.4 56.7 -59.0 -44.1 1.4 52.1 4.6 70 81 A K H 3<5S+ 0 0 78 -4,-2.1 2,-0.8 1,-0.3 -1,-0.2 0.919 115.9 34.5 -59.3 -48.2 -1.7 50.0 3.8 71 82 A L T 3<5S- 0 0 102 -4,-1.5 -1,-0.3 -5,-0.1 -2,-0.1 -0.635 110.9-122.4-105.2 67.2 -2.7 49.7 7.4 72 83 A K T < 5S+ 0 0 167 -3,-0.9 -3,-0.2 -2,-0.8 -2,-0.1 0.288 70.9 124.4 -18.1 97.4 -1.5 53.2 8.4 73 84 A Q >< + 0 0 64 -5,-1.1 4,-1.7 2,-0.1 5,-0.2 -0.053 25.5 125.4-149.9 26.4 1.1 52.7 11.2 74 85 A I H > S+ 0 0 25 -6,-0.2 4,-1.8 1,-0.2 5,-0.2 0.906 75.2 53.1 -55.5 -46.1 4.0 54.5 9.5 75 86 A E H > S+ 0 0 58 1,-0.2 4,-2.8 2,-0.2 -1,-0.2 0.901 105.8 54.2 -59.9 -41.2 4.4 56.7 12.5 76 87 A H H > S+ 0 0 20 1,-0.2 4,-2.4 2,-0.2 -1,-0.2 0.895 109.6 45.3 -61.7 -43.3 4.6 53.7 14.8 77 88 A T H X S+ 0 0 6 -4,-1.7 4,-1.4 2,-0.2 -1,-0.2 0.786 114.5 49.6 -72.6 -27.4 7.5 52.0 12.9 78 89 A L H X S+ 0 0 37 -4,-1.8 4,-1.9 2,-0.2 -2,-0.2 0.873 111.1 50.0 -74.0 -38.9 9.3 55.4 12.7 79 90 A N H X S+ 0 0 33 -4,-2.8 4,-2.3 1,-0.2 5,-0.3 0.936 108.0 54.8 -60.5 -47.3 8.7 55.8 16.5 80 91 A E H X S+ 0 0 7 -4,-2.4 4,-2.3 95,-0.3 5,-0.2 0.911 111.6 40.9 -53.3 -53.2 10.1 52.3 17.1 81 92 A K H X S+ 0 0 5 -4,-1.4 4,-2.5 2,-0.2 -1,-0.2 0.914 114.7 49.5 -65.6 -46.6 13.4 52.9 15.4 82 93 A R H X S+ 0 0 77 -4,-1.9 4,-1.1 2,-0.2 -2,-0.2 0.894 115.5 43.8 -64.6 -39.7 14.2 56.4 16.6 83 94 A I H >X S+ 0 0 0 -4,-2.3 4,-2.0 -5,-0.2 3,-0.5 0.952 114.3 48.8 -68.6 -51.5 13.5 55.5 20.3 84 95 A L H 3< S+ 0 0 6 -4,-2.3 11,-0.5 -5,-0.3 -2,-0.2 0.879 111.9 50.2 -54.2 -42.8 15.4 52.2 20.1 85 96 A Q H 3< S+ 0 0 23 -4,-2.5 -1,-0.3 1,-0.2 -2,-0.2 0.788 114.9 44.7 -64.1 -31.9 18.3 54.0 18.5 86 97 A A H << S+ 0 0 6 -4,-1.1 -68,-0.2 -3,-0.5 -2,-0.2 0.736 97.2 82.5 -91.4 -23.7 18.3 56.7 21.2 87 98 A V < - 0 0 19 -4,-2.0 2,-0.2 -69,-0.1 8,-0.2 -0.308 44.9-179.3 -85.9 166.8 17.9 54.6 24.5 88 99 A N + 0 0 133 -2,-0.1 -73,-0.1 6,-0.1 5,-0.1 -0.729 22.8 132.8-167.1 108.6 20.4 52.9 26.6 89 100 A F > - 0 0 17 3,-0.2 3,-1.9 -2,-0.2 53,-0.0 -0.966 59.5-111.5-159.3 143.8 19.6 50.9 29.8 90 101 A P T 3 S+ 0 0 40 0, 0.0 4,-0.1 0, 0.0 78,-0.0 0.652 114.3 47.9 -57.8 -18.0 20.6 47.4 31.0 91 102 A F T 3 S+ 0 0 0 47,-0.1 80,-3.1 79,-0.1 2,-0.4 0.189 94.8 87.9-111.0 15.0 17.2 45.9 30.7 92 103 A L B < S-e 171 0B 9 -3,-1.9 -3,-0.2 78,-0.3 2,-0.2 -0.927 84.2-110.7-112.6 137.7 16.4 47.2 27.2 93 104 A V - 0 0 4 78,-2.9 2,-0.4 -2,-0.4 -2,-0.1 -0.472 38.1-122.0 -66.6 131.8 17.4 45.3 24.0 94 105 A K - 0 0 38 -2,-0.2 16,-1.8 -4,-0.1 2,-0.8 -0.664 9.6-141.1 -83.3 126.9 20.1 47.1 22.1 95 106 A L E +D 109 0A 29 -11,-0.5 14,-0.3 -2,-0.4 3,-0.1 -0.786 23.4 175.5 -84.5 110.0 19.7 48.2 18.5 96 107 A E E + 0 0 89 12,-1.8 2,-0.3 -2,-0.8 13,-0.2 0.905 61.0 4.2 -82.6 -45.3 23.1 47.6 16.8 97 108 A F E -D 108 0A 47 11,-2.2 11,-3.2 2,-0.0 2,-0.3 -0.953 56.3-170.8-140.9 158.6 22.3 48.6 13.2 98 109 A S E +D 107 0A 1 -2,-0.3 -72,-2.5 9,-0.2 -71,-0.5 -0.991 18.3 139.9-150.9 146.4 19.5 50.0 11.1 99 110 A F E -D 106 0A 6 7,-2.0 7,-2.7 -2,-0.3 2,-0.3 -0.964 27.1-142.8-168.1 171.5 18.8 50.4 7.4 100 111 A K E -D 105 0A 66 -2,-0.3 5,-0.2 5,-0.2 2,-0.2 -0.963 10.4-170.1-142.4 159.0 16.1 50.1 4.7 101 112 A D - 0 0 38 3,-2.4 230,-0.2 -2,-0.3 226,-0.0 -0.638 52.9 -62.4-132.5-160.4 15.9 49.0 1.1 102 113 A N S S+ 0 0 52 225,-0.2 229,-2.7 -2,-0.2 226,-0.1 0.788 130.1 15.8 -59.0 -28.0 13.4 49.1 -1.8 103 114 A S S S+ 0 0 7 227,-0.2 -38,-2.6 224,-0.1 -37,-0.4 0.706 118.6 42.4-116.2 -32.0 10.8 47.0 0.1 104 115 A N E -C 64 0A 8 -40,-0.2 -3,-2.4 -39,-0.1 2,-0.4 -0.752 56.3-132.5-129.5 167.4 11.6 46.8 3.8 105 116 A L E -CD 63 100A 0 -42,-2.3 -42,-2.7 -2,-0.3 2,-0.4 -0.909 29.3-157.3-110.8 140.1 12.7 48.4 6.9 106 117 A Y E -CD 62 99A 0 -7,-2.7 -7,-2.0 -2,-0.4 2,-0.5 -0.983 17.3-179.7-131.9 131.2 15.4 46.7 9.0 107 118 A M E -CD 61 98A 0 -46,-2.0 -46,-3.3 -2,-0.4 2,-0.8 -0.985 13.9-158.8-126.1 114.3 16.4 46.9 12.6 108 119 A V E +CD 60 97A 0 -11,-3.2 -11,-2.2 -2,-0.5 -12,-1.8 -0.844 21.6 176.0-102.5 101.1 19.3 44.7 13.7 109 120 A M E -CD 59 95A 4 -50,-2.7 -50,-2.0 -2,-0.8 -14,-0.2 -0.383 38.2 -76.9 -94.4 174.4 19.2 44.2 17.5 110 121 A E E -C 58 0A 87 -16,-1.8 2,-0.7 -52,-0.2 -52,-0.2 -0.483 46.7-118.5 -72.1 141.2 21.2 42.1 19.9 111 122 A Y - 0 0 17 -54,-0.6 2,-0.8 -2,-0.1 -54,-0.1 -0.807 25.4-167.8 -88.4 116.6 20.5 38.4 19.9 112 123 A V > - 0 0 6 -2,-0.7 3,-1.3 1,-0.1 51,-0.2 -0.882 1.5-167.2-105.9 96.5 19.2 37.3 23.2 113 124 A A T 3 S+ 0 0 8 -2,-0.8 202,-0.5 1,-0.2 51,-0.1 0.627 72.1 79.3 -64.2 -17.5 19.4 33.4 23.1 114 125 A G T 3 S- 0 0 0 49,-0.5 -1,-0.2 1,-0.2 50,-0.1 0.609 89.0-144.6 -70.2 -13.1 17.3 32.8 26.3 115 126 A G < - 0 0 0 -3,-1.3 48,-2.9 190,-0.1 -1,-0.2 -0.064 35.6 -26.5 78.5-179.8 13.9 33.5 24.4 116 127 A E B >> -F 162 0B 42 199,-0.3 4,-1.1 46,-0.2 3,-0.6 -0.390 46.5-129.3 -72.5 145.1 10.7 35.1 25.5 117 128 A M H 3> S+ 0 0 0 44,-3.0 4,-2.8 41,-0.9 5,-0.2 0.828 106.2 68.8 -60.4 -33.7 9.5 35.2 29.1 118 129 A F H 3> S+ 0 0 70 40,-1.1 4,-2.3 43,-0.3 -1,-0.2 0.865 96.9 51.3 -51.0 -47.6 6.1 33.8 27.8 119 130 A S H <> S+ 0 0 20 -3,-0.6 4,-2.1 1,-0.2 -1,-0.2 0.922 113.9 42.3 -57.5 -49.1 7.7 30.4 27.0 120 131 A H H X S+ 0 0 6 -4,-1.1 4,-2.2 2,-0.2 -2,-0.2 0.872 113.4 51.7 -71.5 -37.6 9.3 30.0 30.4 121 132 A L H X S+ 0 0 0 -4,-2.8 4,-1.5 2,-0.2 -2,-0.2 0.923 113.2 45.9 -64.1 -42.6 6.2 31.2 32.4 122 133 A R H < S+ 0 0 103 -4,-2.3 -2,-0.2 -5,-0.2 -1,-0.2 0.902 112.4 50.4 -65.8 -40.7 4.0 28.8 30.5 123 134 A R H < S+ 0 0 166 -4,-2.1 -2,-0.2 1,-0.2 -1,-0.2 0.891 116.9 39.9 -63.2 -41.8 6.4 25.9 31.0 124 135 A I H < S- 0 0 95 -4,-2.2 2,-1.1 1,-0.1 -1,-0.2 0.664 100.4-135.3 -83.5 -17.1 6.7 26.5 34.7 125 136 A G S < S- 0 0 42 -4,-1.5 2,-0.3 -5,-0.2 -1,-0.1 -0.511 74.6 -5.6 94.2 -64.7 3.0 27.3 35.2 126 137 A R S S- 0 0 128 -2,-1.1 2,-0.3 -3,-0.1 95,-0.2 -0.978 72.9-114.2-154.6 157.7 3.6 30.3 37.4 127 138 A F - 0 0 4 93,-3.3 96,-0.0 -2,-0.3 -6,-0.0 -0.703 32.5-111.2 -95.0 152.1 6.5 32.1 39.1 128 139 A S > - 0 0 70 -2,-0.3 4,-3.0 1,-0.1 5,-0.2 -0.327 35.3-105.7 -68.8 162.8 7.1 32.3 42.8 129 140 A E H > S+ 0 0 34 1,-0.2 4,-2.4 2,-0.2 5,-0.2 0.916 122.2 51.3 -63.6 -39.4 6.7 35.8 44.3 130 141 A P H > S+ 0 0 83 0, 0.0 4,-1.4 0, 0.0 -1,-0.2 0.897 113.9 45.5 -56.6 -39.4 10.6 36.1 44.8 131 142 A H H > S+ 0 0 10 2,-0.2 4,-1.6 1,-0.2 3,-0.2 0.941 114.5 46.1 -70.9 -46.9 11.0 35.2 41.1 132 143 A A H X S+ 0 0 0 -4,-3.0 4,-2.7 1,-0.2 -1,-0.2 0.861 111.3 54.3 -61.8 -36.6 8.2 37.5 39.9 133 144 A R H X S+ 0 0 36 -4,-2.4 4,-2.5 -5,-0.2 -1,-0.2 0.803 102.2 57.0 -65.5 -37.3 9.6 40.3 42.1 134 145 A F H X S+ 0 0 11 -4,-1.4 4,-1.1 -3,-0.2 -1,-0.2 0.946 114.3 38.8 -59.0 -50.3 13.1 40.0 40.5 135 146 A Y H X S+ 0 0 0 -4,-1.6 4,-1.6 1,-0.2 -2,-0.2 0.899 115.0 52.9 -66.2 -43.2 11.5 40.6 37.1 136 147 A A H X S+ 0 0 0 -4,-2.7 4,-2.5 1,-0.2 -2,-0.2 0.863 103.6 57.0 -62.9 -37.7 9.1 43.3 38.3 137 148 A A H X S+ 0 0 0 -4,-2.5 4,-2.2 1,-0.2 -1,-0.2 0.891 107.0 50.1 -59.2 -40.1 11.9 45.2 39.9 138 149 A Q H X S+ 0 0 0 -4,-1.1 4,-2.1 2,-0.2 -1,-0.2 0.855 110.2 48.3 -67.8 -38.6 13.6 45.4 36.5 139 150 A I H X S+ 0 0 0 -4,-1.6 4,-2.9 2,-0.2 5,-0.2 0.900 108.8 55.2 -68.4 -41.2 10.4 46.6 34.8 140 151 A V H X S+ 0 0 0 -4,-2.5 4,-2.3 1,-0.2 -2,-0.2 0.945 113.2 41.1 -55.5 -52.8 10.0 49.3 37.5 141 152 A L H X S+ 0 0 8 -4,-2.2 4,-2.2 2,-0.2 -1,-0.2 0.869 113.4 53.8 -65.0 -37.2 13.5 50.7 36.9 142 153 A T H X S+ 0 0 0 -4,-2.1 4,-2.6 1,-0.2 -2,-0.2 0.918 112.9 43.1 -64.2 -44.7 13.1 50.4 33.1 143 154 A F H X S+ 0 0 1 -4,-2.9 4,-3.4 2,-0.2 5,-0.3 0.851 108.6 57.8 -69.8 -36.3 9.9 52.4 33.2 144 155 A E H X S+ 0 0 25 -4,-2.3 4,-1.2 -5,-0.2 -2,-0.2 0.941 113.1 42.3 -56.4 -44.9 11.4 54.9 35.6 145 156 A Y H X S+ 0 0 9 -4,-2.2 4,-0.8 2,-0.2 -2,-0.2 0.941 117.5 44.7 -64.0 -51.9 14.1 55.5 33.0 146 157 A L H ><>S+ 0 0 1 -4,-2.6 5,-2.2 1,-0.2 3,-0.7 0.885 111.9 51.2 -66.1 -39.4 11.7 55.5 30.0 147 158 A H H ><5S+ 0 0 22 -4,-3.4 3,-1.3 1,-0.2 -1,-0.2 0.807 103.6 60.3 -68.6 -26.3 9.1 57.8 31.6 148 159 A S H 3<5S+ 0 0 36 -4,-1.2 -1,-0.2 -5,-0.3 -2,-0.2 0.793 102.9 52.2 -63.9 -29.4 12.0 60.2 32.5 149 160 A L T <<5S- 0 0 0 -4,-0.8 -1,-0.2 -3,-0.7 -2,-0.2 0.207 122.9-107.3 -93.1 11.4 12.6 60.5 28.7 150 161 A D T < 5S+ 0 0 38 -3,-1.3 30,-3.4 1,-0.3 2,-0.4 0.724 76.4 140.8 62.9 30.0 8.9 61.3 28.1 151 162 A L E < -H 179 0C 3 -5,-2.2 2,-0.5 28,-0.3 -1,-0.3 -0.806 40.9-160.3-102.8 139.2 8.5 57.9 26.6 152 163 A I E -H 178 0C 5 26,-2.6 26,-2.1 -2,-0.4 2,-0.9 -0.984 8.1-154.3-113.9 124.0 5.5 55.6 27.0 153 164 A Y - 0 0 1 -2,-0.5 3,-0.4 24,-0.2 2,-0.2 -0.827 14.8-169.4 -92.2 100.7 6.2 51.9 26.3 154 165 A R + 0 0 12 -2,-0.9 36,-0.2 1,-0.2 -1,-0.1 0.128 62.0 58.4 -92.1 32.8 2.7 50.8 25.3 155 166 A D + 0 0 15 -2,-0.2 2,-0.4 34,-0.1 -1,-0.2 -0.105 54.4 166.2-149.7 52.6 2.9 47.0 25.2 156 167 A L + 0 0 3 -3,-0.4 34,-0.1 37,-0.1 59,-0.0 -0.533 25.5 126.4 -75.7 122.7 4.1 45.2 28.4 157 168 A K S > S- 0 0 30 -2,-0.4 3,-1.6 1,-0.1 4,-0.2 -0.934 70.7 -98.7-167.5 153.9 3.4 41.5 28.2 158 169 A P G > S+ 0 0 0 0, 0.0 3,-1.2 0, 0.0 -40,-1.1 0.791 119.3 57.7 -52.0 -35.3 5.5 38.2 28.7 159 170 A E G 3 S+ 0 0 56 1,-0.2 -3,-0.1 -42,-0.2 -40,-0.1 0.743 102.7 56.3 -65.5 -26.6 6.0 37.7 24.9 160 171 A N G < S+ 0 0 8 -3,-1.6 12,-2.3 -5,-0.1 2,-0.4 0.352 95.8 76.4 -90.3 3.5 7.6 41.1 24.7 161 172 A L E < - G 0 171B 0 -3,-1.2 -44,-3.0 -4,-0.2 -43,-0.3 -0.961 64.4-157.4-118.2 136.1 10.3 40.4 27.3 162 173 A L E -FG 116 170B 18 8,-2.5 8,-1.9 -2,-0.4 2,-0.5 -0.810 11.7-137.7-109.1 146.9 13.4 38.3 26.6 163 174 A I E - G 0 169B 0 -48,-2.9 -49,-0.5 -2,-0.3 6,-0.2 -0.921 25.5-152.8-103.6 124.0 15.4 36.5 29.2 164 175 A D > - 0 0 12 4,-2.8 3,-1.7 -2,-0.5 -52,-0.1 -0.192 34.5 -83.5 -88.4-172.0 19.2 36.7 28.7 165 176 A Q T 3 S+ 0 0 43 1,-0.3 -1,-0.1 2,-0.1 142,-0.1 0.689 129.5 48.4 -61.6 -25.2 22.2 34.6 29.6 166 177 A Q T 3 S- 0 0 107 2,-0.1 135,-0.3 138,-0.1 -1,-0.3 0.374 120.3-108.3 -96.1 3.5 22.4 36.0 33.1 167 178 A G S < S+ 0 0 0 -3,-1.7 2,-0.2 1,-0.3 -2,-0.1 0.489 77.5 131.5 82.4 5.2 18.6 35.5 33.7 168 179 A Y - 0 0 4 1,-0.1 -4,-2.8 133,-0.1 -1,-0.3 -0.511 60.3 -97.2 -88.3 159.2 17.9 39.2 33.4 169 180 A I E - G 0 163B 0 -6,-0.2 2,-0.4 -2,-0.2 -6,-0.2 -0.459 25.4-169.6 -77.7 144.2 15.2 40.9 31.3 170 181 A Q E - G 0 162B 13 -8,-1.9 -8,-2.5 -2,-0.1 2,-0.3 -0.957 20.0-145.4-130.3 106.3 15.7 42.5 27.9 171 182 A V E +eG 92 161B 1 -80,-3.1 -78,-2.9 -2,-0.4 -10,-0.2 -0.605 28.0 166.9 -74.9 131.7 12.6 44.5 26.9 172 183 A T + 0 0 17 -12,-2.3 -12,-0.1 -2,-0.3 -1,-0.0 -0.496 37.1 75.6-126.7-163.4 11.9 44.4 23.2 173 184 A D > + 0 0 54 -2,-0.2 3,-0.5 1,-0.1 -1,-0.1 0.965 39.2 167.3 52.9 64.8 8.9 45.4 21.0 174 185 A F G > + 0 0 2 1,-0.2 3,-1.0 2,-0.1 -1,-0.1 0.214 41.2 115.9 -86.7 13.6 9.1 49.1 21.0 175 186 A G G 3 S+ 0 0 18 1,-0.3 -95,-0.3 -95,-0.1 -1,-0.2 0.811 82.2 35.0 -53.9 -38.7 6.6 49.1 18.1 176 187 A F G < S+ 0 0 56 -3,-0.5 -1,-0.3 -97,-0.1 -22,-0.1 0.447 92.2 120.4 -97.8 0.7 4.0 50.9 20.2 177 188 A A < + 0 0 1 -3,-1.0 2,-0.3 -24,-0.2 -24,-0.2 -0.340 39.3 179.7 -67.1 141.3 6.5 53.1 22.1 178 189 A K E -H 152 0C 38 -26,-2.1 -26,-2.6 -2,-0.1 2,-0.6 -0.998 30.6-128.9-145.7 142.0 6.1 56.9 21.8 179 190 A R E +H 151 0C 48 -2,-0.3 2,-0.3 -28,-0.2 -28,-0.3 -0.854 45.0 155.5 -90.5 121.4 7.7 60.0 23.0 180 191 A V - 0 0 28 -30,-3.4 2,-0.8 -2,-0.6 4,-0.1 -0.978 42.2-146.7-151.4 137.8 5.0 62.4 24.4 181 192 A K S S- 0 0 154 -2,-0.3 2,-0.5 2,-0.1 -2,-0.0 -0.902 85.1 -16.9-100.0 99.0 4.8 65.2 26.9 182 193 A G S S- 0 0 45 -2,-0.8 24,-0.3 2,-0.0 2,-0.2 -0.885 113.1 -1.5 111.3-130.0 1.4 64.7 28.4 183 194 A R - 0 0 164 -2,-0.5 2,-0.3 22,-0.1 22,-0.2 -0.565 46.7-166.4-102.5 162.3 -1.4 62.5 26.8 184 195 A T B -I 204 0D 4 20,-2.1 20,-2.2 -2,-0.2 -4,-0.0 -0.925 9.9-156.0-139.3 162.8 -1.9 60.4 23.7 185 196 A W + 0 0 170 -2,-0.3 2,-0.2 18,-0.2 20,-0.0 0.400 42.6 127.7-125.3 0.4 -5.0 58.9 22.1 186 197 A X - 0 0 72 1,-0.1 2,-1.4 15,-0.0 -2,-0.1 -0.397 56.9-131.0 -70.0 131.8 -4.1 55.9 19.9 187 198 A L + 0 0 127 -2,-0.2 2,-0.3 14,-0.1 -1,-0.1 -0.695 59.7 130.0 -79.2 93.1 -5.9 52.6 20.5 188 199 A C + 0 0 13 -2,-1.4 2,-0.3 2,-0.1 10,-0.0 -0.968 20.1 66.2-145.0 163.6 -3.0 50.3 20.7 189 200 A G S S- 0 0 21 -2,-0.3 -34,-0.1 -34,-0.1 -35,-0.1 -0.882 85.3 -51.8 123.0-156.8 -1.5 47.6 22.9 190 201 A T >> - 0 0 18 -2,-0.3 3,-2.3 -36,-0.2 4,-0.7 -0.983 48.8-117.4-124.0 134.1 -2.8 44.1 23.7 191 202 A P G >4 S+ 0 0 35 0, 0.0 3,-0.7 0, 0.0 -1,-0.1 0.732 108.0 45.2 -37.9 -51.4 -6.4 43.4 25.0 192 203 A E G 34 S+ 0 0 53 1,-0.2 35,-0.3 37,-0.0 0, 0.0 0.544 115.4 48.4 -79.5 -1.9 -5.8 41.9 28.5 193 204 A Y G <4 S+ 0 0 15 -3,-2.3 -1,-0.2 2,-0.1 2,-0.2 0.481 82.9 119.8-110.9 -6.5 -3.2 44.5 29.4 194 205 A L << - 0 0 11 -4,-0.7 -5,-0.1 -3,-0.7 -39,-0.0 -0.420 58.9-133.7 -70.9 128.7 -5.2 47.6 28.4 195 206 A A >> - 0 0 0 -2,-0.2 4,-1.7 1,-0.1 3,-0.5 -0.339 27.5-105.3 -71.7 157.0 -6.0 50.1 31.0 196 207 A P H 3> S+ 0 0 7 0, 0.0 4,-2.8 0, 0.0 6,-0.1 0.804 116.7 62.1 -54.9 -31.5 -9.6 51.6 31.3 197 208 A E H 34>S+ 0 0 9 2,-0.2 5,-3.1 1,-0.2 -3,-0.0 0.903 105.3 44.7 -61.5 -47.2 -8.5 54.9 29.8 198 209 A I H X45S+ 0 0 8 -3,-0.5 3,-1.7 3,-0.2 -1,-0.2 0.943 113.6 49.4 -66.2 -48.6 -7.5 53.3 26.5 199 210 A I H 3<5S+ 0 0 33 -4,-1.7 -2,-0.2 1,-0.3 -1,-0.2 0.934 111.8 48.9 -57.9 -44.4 -10.7 51.2 26.3 200 211 A L T 3<5S- 0 0 85 -4,-2.8 -1,-0.3 -5,-0.2 -2,-0.2 0.235 116.9-114.7 -83.9 17.3 -12.9 54.2 27.1 201 212 A S T < 5 + 0 0 98 -3,-1.7 -3,-0.2 1,-0.2 2,-0.2 0.798 63.3 149.6 54.5 41.2 -11.1 56.2 24.3 202 213 A K < - 0 0 113 -5,-3.1 2,-0.9 -6,-0.1 -1,-0.2 -0.526 58.9 -95.0 -97.6 164.0 -9.5 58.8 26.7 203 214 A G - 0 0 20 -2,-0.2 2,-0.2 -20,-0.1 -18,-0.2 -0.725 56.2-172.9 -77.6 107.8 -6.3 60.8 26.5 204 215 A Y B -I 184 0D 4 -20,-2.2 -20,-2.1 -2,-0.9 2,-0.2 -0.647 14.3-167.7-108.3 163.5 -4.0 58.7 28.5 205 216 A N > - 0 0 36 -2,-0.2 3,-2.0 -22,-0.2 4,-0.2 -0.485 54.3 -51.3-128.3-161.0 -0.4 59.0 29.8 206 217 A K T >> S+ 0 0 67 -24,-0.3 3,-1.6 1,-0.3 4,-0.8 0.637 114.3 82.5 -53.0 -21.4 2.4 56.9 31.4 207 218 A A H 3> S+ 0 0 0 1,-0.3 4,-1.6 2,-0.2 -1,-0.3 0.728 78.5 70.8 -55.6 -26.9 -0.1 55.6 34.1 208 219 A V H <> S+ 0 0 8 -3,-2.0 4,-1.9 1,-0.2 -1,-0.3 0.803 95.2 52.1 -57.9 -37.8 -1.1 53.1 31.4 209 220 A D H <> S+ 0 0 1 -3,-1.6 4,-1.7 -4,-0.2 -1,-0.2 0.806 106.3 52.6 -71.6 -31.8 2.3 51.3 31.8 210 221 A W H X S+ 0 0 2 -4,-0.8 4,-1.3 2,-0.2 -2,-0.2 0.805 108.0 50.5 -76.6 -29.5 1.8 51.0 35.5 211 222 A W H X S+ 0 0 1 -4,-1.6 4,-1.9 2,-0.2 3,-0.4 0.938 109.5 52.5 -64.4 -48.8 -1.6 49.4 35.0 212 223 A A H X S+ 0 0 6 -4,-1.9 4,-2.5 1,-0.3 -2,-0.2 0.842 104.9 55.1 -55.7 -36.2 0.2 47.0 32.6 213 224 A L H X S+ 0 0 0 -4,-1.7 4,-3.0 2,-0.2 -1,-0.3 0.895 104.3 53.8 -64.2 -40.1 2.8 46.2 35.3 214 225 A G H X S+ 0 0 0 -4,-1.3 4,-2.5 -3,-0.4 -2,-0.2 0.932 112.0 45.0 -57.1 -44.8 -0.1 45.2 37.6 215 226 A V H X S+ 0 0 0 -4,-1.9 4,-2.5 2,-0.2 -2,-0.2 0.886 113.2 50.2 -65.9 -42.0 -1.4 42.8 35.0 216 227 A L H X S+ 0 0 0 -4,-2.5 4,-2.6 2,-0.2 -2,-0.2 0.935 112.7 46.1 -62.9 -48.4 2.2 41.5 34.3 217 228 A I H X S+ 0 0 0 -4,-3.0 4,-2.4 2,-0.2 5,-0.2 0.895 112.3 50.7 -64.8 -40.6 2.8 40.9 38.0 218 229 A Y H X S+ 0 0 8 -4,-2.5 4,-2.3 -5,-0.2 6,-0.3 0.940 113.2 46.6 -61.3 -44.4 -0.6 39.2 38.4 219 230 A E H X S+ 0 0 2 -4,-2.5 4,-2.3 2,-0.2 -2,-0.2 0.879 112.1 49.0 -66.0 -39.3 0.2 37.0 35.4 220 231 A M H < S+ 0 0 0 -4,-2.6 -93,-3.3 1,-0.2 -2,-0.2 0.949 118.8 39.2 -65.6 -45.4 3.7 36.1 36.6 221 232 A A H < S+ 0 0 2 -4,-2.4 -2,-0.2 -95,-0.2 -1,-0.2 0.751 127.8 32.3 -77.1 -25.2 2.5 35.2 40.1 222 233 A A H < S- 0 0 9 -4,-2.3 -3,-0.2 2,-0.2 -2,-0.2 0.721 96.6-124.7-102.7 -26.0 -0.8 33.5 39.0 223 234 A G S < S+ 0 0 15 -4,-2.3 -4,-0.2 -5,-0.3 -3,-0.1 0.160 88.6 60.2 98.0 -19.4 0.1 31.9 35.7 224 235 A Y S S- 0 0 100 -6,-0.3 -2,-0.2 4,-0.0 -1,-0.2 -0.943 91.0 -98.0-136.6 156.5 -2.9 33.7 34.0 225 236 A P - 0 0 17 0, 0.0 -9,-0.1 0, 0.0 -10,-0.1 -0.412 31.8-119.0 -70.8 151.5 -3.9 37.4 33.5 226 237 A P S S+ 0 0 14 0, 0.0 2,-0.5 0, 0.0 19,-0.3 0.774 102.3 46.1 -61.8 -29.5 -6.4 39.1 35.9 227 238 A F S S+ 0 0 8 -35,-0.3 2,-0.3 17,-0.1 8,-0.1 -0.952 74.0 158.1-123.3 111.3 -8.9 39.8 33.1 228 239 A F + 0 0 106 -2,-0.5 2,-0.3 6,-0.1 3,-0.1 -0.980 1.6 140.4-134.9 146.8 -9.7 37.0 30.7 229 240 A A - 0 0 36 -2,-0.3 6,-0.1 1,-0.1 -37,-0.0 -0.958 53.8-105.6-171.3 166.0 -12.5 36.1 28.3 230 241 A D S S+ 0 0 161 -2,-0.3 -1,-0.1 1,-0.1 3,-0.0 0.917 104.1 44.0 -68.7 -45.9 -13.1 34.6 24.8 231 242 A Q S >> S- 0 0 28 1,-0.1 3,-1.2 -3,-0.1 4,-1.0 -0.838 81.2-128.8-103.5 140.0 -14.1 37.9 23.1 232 243 A P H 3> S+ 0 0 63 0, 0.0 4,-2.4 0, 0.0 3,-0.4 0.828 107.8 64.1 -51.0 -36.4 -12.2 41.2 23.6 233 244 A I H 3> S+ 0 0 104 1,-0.2 4,-1.5 2,-0.2 5,-0.1 0.858 104.1 45.9 -57.8 -36.1 -15.5 42.9 24.4 234 245 A Q H <> S+ 0 0 84 -3,-1.2 4,-1.1 2,-0.2 -1,-0.2 0.727 109.5 53.7 -82.1 -24.0 -15.9 40.8 27.5 235 246 A I H X S+ 0 0 5 -4,-1.0 4,-1.5 -3,-0.4 -2,-0.2 0.915 108.6 51.3 -70.8 -43.7 -12.3 41.3 28.6 236 247 A Y H X S+ 0 0 61 -4,-2.4 4,-2.6 1,-0.2 5,-0.2 0.866 104.8 53.8 -65.0 -41.2 -12.8 45.1 28.4 237 248 A E H X S+ 0 0 121 -4,-1.5 4,-1.7 1,-0.2 -1,-0.2 0.908 109.9 50.1 -57.3 -42.6 -16.0 45.1 30.6 238 249 A K H < S+ 0 0 85 -4,-1.1 5,-0.4 2,-0.2 -1,-0.2 0.797 111.6 47.7 -66.4 -33.3 -14.0 43.2 33.3 239 250 A I H < S+ 0 0 0 -4,-1.5 -2,-0.2 1,-0.1 -1,-0.2 0.924 111.8 48.6 -72.3 -48.7 -11.2 45.8 33.1 240 251 A V H < S+ 0 0 55 -4,-2.6 -2,-0.2 -5,-0.1 -3,-0.2 0.784 96.3 81.6 -66.2 -26.8 -13.6 48.9 33.3 241 252 A S S < S- 0 0 39 -4,-1.7 23,-0.0 -5,-0.2 0, 0.0 -0.309 92.4-123.6 -65.6 159.9 -15.4 47.4 36.3 242 253 A G S S+ 0 0 64 21,-0.1 2,-0.4 22,-0.0 -1,-0.1 0.001 76.7 111.8 -99.1 36.9 -13.4 48.1 39.5 243 254 A K + 0 0 156 -5,-0.4 2,-0.3 -4,-0.0 -2,-0.1 -0.903 33.0 158.3-119.1 133.4 -13.3 44.5 40.3 244 255 A V - 0 0 39 -2,-0.4 2,-0.4 -17,-0.0 -17,-0.1 -0.983 25.7-143.2-150.4 131.4 -10.4 41.9 40.3 245 256 A R - 0 0 78 -19,-0.3 -2,-0.0 -2,-0.3 0, 0.0 -0.847 14.4-149.9 -99.8 141.8 -10.2 38.5 42.1 246 257 A F - 0 0 37 -2,-0.4 -2,-0.0 4,-0.0 9,-0.0 -0.899 19.3-112.2-111.5 138.5 -6.9 37.2 43.7 247 258 A P > - 0 0 16 0, 0.0 3,-1.2 0, 0.0 -1,-0.0 -0.327 29.4-119.2 -58.0 147.6 -5.7 33.6 44.1 248 259 A S T 3 S+ 0 0 125 1,-0.2 -2,-0.0 0, 0.0 0, 0.0 0.786 109.7 65.0 -61.2 -28.2 -5.5 32.5 47.8 249 260 A H T 3 S+ 0 0 81 -27,-0.0 -1,-0.2 2,-0.0 2,-0.1 0.704 77.8 105.8 -74.0 -16.1 -1.8 31.8 47.5 250 261 A F S < S- 0 0 6 -3,-1.2 -4,-0.0 1,-0.1 -28,-0.0 -0.359 75.6-118.5 -62.1 134.5 -1.1 35.5 46.9 251 262 A S > - 0 0 40 1,-0.1 4,-2.4 -2,-0.1 5,-0.2 -0.283 20.7-114.1 -69.5 160.2 0.5 37.3 49.9 252 263 A S H > S+ 0 0 97 1,-0.2 4,-1.6 2,-0.2 -1,-0.1 0.848 118.7 54.1 -63.6 -33.2 -1.3 40.2 51.5 253 264 A D H > S+ 0 0 76 2,-0.2 4,-2.0 1,-0.2 32,-0.3 0.870 108.6 47.7 -66.5 -39.8 1.5 42.5 50.3 254 265 A L H > S+ 0 0 0 2,-0.2 4,-2.5 1,-0.2 -2,-0.2 0.949 110.7 50.8 -68.3 -47.5 1.1 41.4 46.7 255 266 A K H X S+ 0 0 51 -4,-2.4 4,-1.7 1,-0.2 -2,-0.2 0.812 112.2 48.6 -57.4 -34.0 -2.7 41.8 46.8 256 267 A D H X S+ 0 0 78 -4,-1.6 4,-1.2 2,-0.2 -1,-0.2 0.898 111.6 47.2 -75.6 -41.7 -2.3 45.3 48.2 257 268 A L H X S+ 0 0 0 -4,-2.0 4,-1.4 1,-0.2 -2,-0.2 0.896 113.1 50.6 -63.2 -41.2 0.3 46.4 45.6 258 269 A L H X S+ 0 0 0 -4,-2.5 4,-3.0 1,-0.2 -2,-0.2 0.866 104.8 55.4 -68.3 -38.0 -1.9 45.0 42.8 259 270 A R H < S+ 0 0 132 -4,-1.7 -1,-0.2 1,-0.2 -2,-0.2 0.836 112.6 44.1 -60.2 -35.2 -5.0 46.8 44.0 260 271 A N H < S+ 0 0 43 -4,-1.2 10,-2.4 1,-0.1 3,-0.4 0.704 117.7 43.7 -83.3 -23.8 -3.1 50.1 43.8 261 272 A L H < S+ 0 0 0 -4,-1.4 -47,-0.2 8,-0.2 -2,-0.2 0.795 115.9 48.4 -84.1 -38.5 -1.5 49.2 40.4 262 273 A L S < S+ 0 0 11 -4,-3.0 2,-0.6 -5,-0.2 -1,-0.2 -0.132 79.8 141.9 -96.8 39.6 -4.8 47.9 39.0 263 274 A Q - 0 0 54 -3,-0.4 6,-0.1 1,-0.1 5,-0.1 -0.717 44.9-152.1 -80.8 117.5 -6.6 51.0 40.2 264 275 A V S S+ 0 0 47 -2,-0.6 2,-0.8 1,-0.1 -1,-0.1 0.806 81.0 76.1 -65.1 -28.7 -9.2 51.8 37.6 265 276 A D S > S- 0 0 60 1,-0.1 3,-1.7 -69,-0.1 4,-0.4 -0.777 73.9-155.1 -85.8 113.9 -9.1 55.6 38.4 266 277 A L T 3 S+ 0 0 56 -2,-0.8 3,-0.2 1,-0.3 -1,-0.1 0.633 89.2 62.6 -65.5 -19.2 -5.9 56.8 36.9 267 278 A T T 3 S+ 0 0 86 1,-0.2 -1,-0.3 6,-0.0 -3,-0.0 0.600 109.6 41.7 -80.2 -13.2 -5.6 59.7 39.3 268 279 A K S < S+ 0 0 120 -3,-1.7 2,-0.2 -5,-0.1 -2,-0.2 0.390 89.6 115.6-111.4 -1.4 -5.3 57.2 42.2 269 280 A R S > S- 0 0 0 -4,-0.4 3,-1.8 -3,-0.2 -8,-0.2 -0.512 71.2-108.2 -78.2 136.1 -3.0 54.7 40.5 270 281 A F T 3 S+ 0 0 28 -10,-2.4 7,-0.1 1,-0.2 -1,-0.1 -0.279 106.4 32.3 -60.3 143.1 0.5 54.0 41.8 271 282 A G T 3 S+ 0 0 0 5,-0.8 -1,-0.2 -62,-0.0 6,-0.2 0.088 115.5 64.3 91.1 -22.3 3.3 55.3 39.6 272 283 A N S < S+ 0 0 36 -3,-1.8 -2,-0.2 4,-0.2 -3,-0.1 0.221 83.2 94.8-114.0 12.4 1.0 58.2 38.7 273 284 A L S > S- 0 0 59 3,-0.3 3,-1.1 -4,-0.1 -5,-0.1 -0.271 94.4 -87.2 -90.9-176.7 0.6 59.9 42.1 274 285 A K T 3 S+ 0 0 116 1,-0.2 -1,-0.1 2,-0.1 0, 0.0 0.907 127.8 50.8 -56.7 -43.2 2.6 62.8 43.6 275 286 A N T > S- 0 0 81 1,-0.2 3,-1.2 2,-0.1 -1,-0.2 0.547 95.0-165.9 -76.3 -7.4 5.3 60.5 45.0 276 287 A G T X - 0 0 15 -3,-1.1 3,-1.6 1,-0.2 -5,-0.8 -0.262 59.7 -3.7 64.7-139.4 5.8 58.8 41.5 277 288 A V T >> S+ 0 0 17 1,-0.3 4,-2.3 -6,-0.2 3,-1.0 0.687 122.2 74.6 -61.0 -21.9 7.7 55.6 41.1 278 289 A N H <> S+ 0 0 50 -3,-1.2 4,-2.1 1,-0.3 -1,-0.3 0.741 80.4 67.6 -71.2 -24.0 8.6 55.6 44.8 279 290 A D H <4 S+ 0 0 36 -3,-1.6 -1,-0.3 2,-0.2 -2,-0.2 0.814 111.7 37.4 -62.6 -25.6 5.1 54.6 45.9 280 291 A I H X4 S+ 0 0 0 -3,-1.0 3,-1.2 -4,-0.4 6,-0.3 0.900 115.3 51.2 -89.1 -49.4 6.0 51.3 44.2 281 292 A K H 3< S+ 0 0 22 -4,-2.3 -2,-0.2 1,-0.3 -3,-0.2 0.768 115.7 43.4 -59.4 -27.9 9.7 51.1 45.2 282 293 A N T 3< S+ 0 0 119 -4,-2.1 -1,-0.3 -5,-0.2 -2,-0.2 0.436 86.8 118.4 -98.2 -2.8 8.8 51.7 48.9 283 294 A H S X S- 0 0 19 -3,-1.2 3,-1.8 -5,-0.1 -3,-0.1 -0.392 76.4-116.7 -64.6 142.8 5.8 49.3 48.9 284 295 A K G > S+ 0 0 53 1,-0.3 3,-0.9 2,-0.2 4,-0.2 0.636 111.0 67.3 -56.4 -20.6 6.2 46.4 51.3 285 296 A W G 3 S+ 0 0 2 -32,-0.3 3,-0.3 1,-0.2 -1,-0.3 0.820 106.3 42.8 -71.1 -29.3 6.1 43.8 48.5 286 297 A F G X S+ 0 0 3 -3,-1.8 3,-1.4 -6,-0.3 -1,-0.2 0.201 79.9 114.5 -97.4 14.7 9.5 45.2 47.4 287 298 A A T < S+ 0 0 82 -3,-0.9 -1,-0.2 1,-0.3 -2,-0.1 0.871 79.4 46.0 -52.4 -41.5 10.9 45.5 51.0 288 299 A T T 3 S+ 0 0 116 -3,-0.3 2,-0.4 -4,-0.2 -1,-0.3 0.565 90.6 111.5 -78.1 -10.9 13.6 42.8 50.3 289 300 A T < - 0 0 22 -3,-1.4 2,-0.9 -8,-0.1 3,-0.1 -0.512 54.7-157.3 -76.6 126.6 14.6 44.4 46.9 290 301 A D > - 0 0 90 -2,-0.4 4,-1.7 1,-0.2 3,-0.3 -0.861 10.6-166.9-102.0 96.6 18.0 46.1 46.7 291 302 A W H > S+ 0 0 40 -2,-0.9 4,-1.8 1,-0.2 -1,-0.2 0.783 81.5 49.1 -59.7 -36.5 17.3 48.5 43.8 292 303 A I H > S+ 0 0 117 2,-0.2 4,-2.4 1,-0.2 -1,-0.2 0.838 111.4 50.7 -75.9 -31.4 20.9 49.5 43.0 293 304 A A H 4>S+ 0 0 11 -3,-0.3 5,-3.0 2,-0.2 6,-0.9 0.799 109.3 50.6 -73.6 -32.9 22.1 45.8 43.0 294 305 A I H ><5S+ 0 0 6 -4,-1.7 3,-1.0 3,-0.2 -2,-0.2 0.925 113.2 46.9 -65.4 -47.7 19.2 44.9 40.6 295 306 A Y H 3<5S+ 0 0 82 -4,-1.8 -2,-0.2 1,-0.2 -3,-0.2 0.931 114.0 45.8 -59.4 -47.6 20.4 47.8 38.3 296 307 A Q T 3<5S- 0 0 101 -4,-2.4 -1,-0.2 -5,-0.1 -2,-0.2 0.427 112.3-124.3 -76.8 1.5 24.1 46.7 38.6 297 308 A R T < 5S+ 0 0 69 -3,-1.0 -3,-0.2 -4,-0.1 -2,-0.1 0.808 71.0 131.9 55.5 40.7 22.9 43.1 37.9 298 309 A K < + 0 0 143 -5,-3.0 2,-0.2 -6,-0.1 -4,-0.2 0.595 40.0 99.8 -91.5 -14.6 24.6 41.8 41.1 299 310 A V S S- 0 0 51 -6,-0.9 2,-0.3 -9,-0.1 0, 0.0 -0.510 81.2-112.2 -76.0 138.8 21.5 39.8 42.2 300 311 A E - 0 0 89 -2,-0.2 -1,-0.1 1,-0.1 -2,-0.1 -0.578 32.7-126.7 -73.0 126.4 21.4 36.1 41.6 301 312 A A - 0 0 24 -2,-0.3 -133,-0.1 -135,-0.3 3,-0.1 -0.534 3.1-137.6 -75.8 140.8 18.7 35.2 39.0 302 313 A P S S+ 0 0 69 0, 0.0 2,-0.3 0, 0.0 -1,-0.1 0.448 90.0 29.2 -79.3 1.0 16.1 32.5 40.0 303 314 A F - 0 0 62 -137,-0.1 -2,-0.0 -136,-0.1 0, 0.0 -0.938 60.5-166.0-161.6 130.6 16.4 31.0 36.5 304 315 A I - 0 0 96 -2,-0.3 -139,-0.1 -3,-0.1 -138,-0.1 -0.996 33.7-117.2-117.8 124.0 19.2 30.8 33.9 305 316 A P - 0 0 6 0, 0.0 2,-0.6 0, 0.0 -191,-0.1 -0.348 24.8-125.5 -58.1 134.5 18.0 29.7 30.3 306 317 A K + 0 0 83 -192,-0.1 2,-0.3 -2,-0.1 9,-0.0 -0.785 54.6 126.0 -86.3 118.0 19.5 26.5 29.1 307 318 A F - 0 0 59 -2,-0.6 -193,-0.1 1,-0.2 -194,-0.0 -0.965 49.1-125.6-160.9 171.0 21.3 26.9 25.8 308 319 A K S S- 0 0 181 1,-0.3 -1,-0.2 -2,-0.3 0, 0.0 0.683 74.6 -1.5 -92.5-113.3 24.7 26.2 24.1 309 320 A G S > S- 0 0 40 1,-0.1 3,-2.1 2,-0.0 -1,-0.3 -0.330 87.0 -90.5 -72.1 168.1 26.7 28.9 22.3 310 321 A P T 3 S+ 0 0 104 0, 0.0 -197,-0.2 0, 0.0 -1,-0.1 0.703 124.6 56.1 -47.6 -28.6 25.4 32.5 21.9 311 322 A G T 3 S+ 0 0 18 -199,-0.1 2,-0.1 -263,-0.0 -253,-0.1 0.266 75.0 129.0 -93.6 9.5 23.7 31.6 18.6 312 323 A D < - 0 0 36 -3,-2.1 3,-0.2 1,-0.1 0, 0.0 -0.417 38.4-168.3 -68.4 137.1 21.5 28.7 19.9 313 324 A T > + 0 0 32 1,-0.1 3,-1.4 -2,-0.1 -1,-0.1 0.209 52.2 113.1-112.4 12.9 17.8 29.0 19.0 314 325 A S T 3 S+ 0 0 84 1,-0.3 -1,-0.1 -199,-0.0 -7,-0.1 0.822 74.7 54.4 -54.3 -39.9 16.4 26.2 21.2 315 326 A N T 3 S+ 0 0 16 -202,-0.5 2,-0.3 -3,-0.2 -199,-0.3 0.600 99.9 72.6 -76.8 -10.1 14.4 28.6 23.5 316 327 A F S < S- 0 0 17 -3,-1.4 -277,-0.1 -201,-0.1 2,-0.1 -0.814 83.9-123.4-101.5 145.8 12.6 30.2 20.5 317 328 A D - 0 0 101 -2,-0.3 2,-0.3 -279,-0.3 -2,-0.1 -0.307 29.3 -89.4 -86.6 170.5 9.9 28.2 18.6 318 329 A D + 0 0 133 -2,-0.1 2,-0.3 -282,-0.0 -1,-0.1 -0.635 39.8 178.1 -90.3 136.5 9.6 27.3 15.0 319 330 A Y - 0 0 84 -282,-0.4 -282,-0.3 -2,-0.3 2,-0.1 -0.933 41.5 -84.4-129.6 152.5 7.9 29.4 12.3 320 331 A E - 0 0 152 -2,-0.3 2,-0.9 1,-0.1 0, 0.0 -0.335 44.1-128.5 -57.2 127.2 7.5 28.9 8.5 321 332 A E - 0 0 82 -2,-0.1 2,-0.2 -284,-0.0 -1,-0.1 -0.745 35.0-180.0 -87.1 106.0 10.5 30.1 6.7 322 333 A E - 0 0 112 -2,-0.9 2,-0.0 1,-0.1 0, 0.0 -0.642 31.1 -86.8-106.9 161.2 9.5 32.5 3.9 323 334 A E - 0 0 168 -2,-0.2 2,-1.2 1,-0.1 -1,-0.1 -0.313 27.6-128.9 -65.1 142.3 11.4 34.5 1.3 324 335 A I - 0 0 36 2,-0.0 2,-0.6 -2,-0.0 -1,-0.1 -0.776 34.2-157.3 -92.3 88.3 12.9 38.0 2.0 325 336 A R - 0 0 70 -2,-1.2 2,-0.6 -222,-0.1 -3,-0.0 -0.598 16.7-179.9 -79.2 112.4 11.4 39.7 -1.0 326 337 A V - 0 0 62 -2,-0.6 -2,-0.0 -223,-0.1 -1,-0.0 -0.955 23.1-136.0-115.8 111.7 13.2 42.9 -2.1 327 338 A X - 0 0 85 -2,-0.6 -225,-0.2 2,-0.2 -224,-0.1 -0.247 12.3-127.6 -65.1 149.4 11.6 44.5 -5.1 328 339 A I S S+ 0 0 140 -226,-0.1 2,-0.3 2,-0.1 -1,-0.1 0.670 96.2 58.1 -72.4 -16.7 13.6 45.9 -8.0 329 340 A N S S- 0 0 87 -227,-0.0 2,-0.3 0, 0.0 -2,-0.2 -0.896 94.2-107.5-115.6 146.4 11.8 49.2 -7.6 330 341 A E - 0 0 131 -2,-0.3 2,-0.5 -227,-0.0 3,-0.2 -0.544 32.9-156.8 -74.4 128.5 11.7 51.4 -4.5 331 342 A K - 0 0 49 -229,-2.7 -266,-0.1 -2,-0.3 -230,-0.1 -0.913 65.8 -11.2-113.2 132.2 8.4 51.4 -2.7 332 343 A C S > S+ 0 0 29 -2,-0.5 4,-1.3 1,-0.1 -1,-0.2 0.814 72.6 157.1 52.6 38.9 7.2 54.2 -0.5 333 344 A G T 4 + 0 0 18 1,-0.2 -1,-0.1 -3,-0.2 -2,-0.1 0.838 69.8 55.2 -58.7 -40.2 10.5 56.0 -0.3 334 345 A K T >4 S+ 0 0 80 1,-0.2 3,-1.3 2,-0.2 -1,-0.2 0.918 105.0 50.5 -62.3 -47.0 8.8 59.3 0.6 335 346 A E T 34 S+ 0 0 79 1,-0.3 3,-0.3 2,-0.1 -1,-0.2 0.831 116.9 41.0 -64.9 -31.2 6.9 58.0 3.6 336 347 A F T >< S+ 0 0 1 -4,-1.3 3,-1.0 1,-0.2 -1,-0.3 0.053 74.4 121.1-107.7 27.3 10.1 56.4 5.2 337 348 A T T < S+ 0 0 96 -3,-1.3 -1,-0.2 1,-0.2 -2,-0.1 0.805 75.3 52.6 -57.4 -30.1 12.6 59.2 4.4 338 349 A E T 3 0 0 126 -3,-0.3 -1,-0.2 -4,-0.2 -2,-0.1 0.691 360.0 360.0 -82.3 -20.2 13.4 59.6 8.1 339 350 A F < 0 0 3 -3,-1.0 -315,-0.1 -315,-0.1 -239,-0.1 -0.486 360.0 360.0 -68.1 360.0 14.2 55.9 8.8