==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=4-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSCRIPTION 14-OCT-07 2RJD . COMPND 2 MOLECULE: LETHAL(3)MALIGNANT BRAIN TUMOR-LIKE PROTEIN; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR A.ALLALI-HASSANI,Y.LIU,N.HERZANYCH,H.OUYANG,F.MACKENZIE, . 321 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 17423.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 185 57.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 13 4.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 70 21.8 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 5 1.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 17 5.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 44 13.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 29 9.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 6 1.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 3 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 5 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 3 1 2 2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 204 A E 0 0 237 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 110.2 -24.9 -15.0 -0.4 2 205 A C - 0 0 129 1,-0.1 2,-0.3 0, 0.0 0, 0.0 -0.061 360.0-117.1 -53.6 139.3 -21.8 -16.1 -2.4 3 206 A W - 0 0 93 4,-0.0 2,-0.4 3,-0.0 -1,-0.1 -0.583 39.0-173.3 -69.7 134.5 -21.0 -14.8 -5.8 4 207 A S > - 0 0 41 -2,-0.3 4,-2.3 1,-0.1 5,-0.1 -0.997 35.2-137.4-134.9 146.7 -21.1 -17.7 -8.3 5 208 A W H > S+ 0 0 31 -2,-0.4 4,-2.9 2,-0.2 5,-0.3 0.890 106.3 58.8 -57.4 -43.4 -20.2 -17.9 -12.0 6 209 A E H > S+ 0 0 145 1,-0.2 4,-1.7 2,-0.2 -1,-0.2 0.938 109.5 41.8 -54.7 -51.9 -23.3 -20.1 -12.5 7 210 A S H > S+ 0 0 47 1,-0.2 4,-2.6 2,-0.2 -1,-0.2 0.919 115.0 51.5 -63.1 -44.9 -25.6 -17.3 -11.2 8 211 A Y H X S+ 0 0 18 -4,-2.3 4,-2.7 1,-0.2 -1,-0.2 0.886 107.8 50.8 -60.8 -44.1 -23.7 -14.6 -13.1 9 212 A L H X>S+ 0 0 29 -4,-2.9 5,-1.8 2,-0.2 4,-1.1 0.877 111.5 48.9 -63.2 -37.6 -23.8 -16.4 -16.4 10 213 A E H <5S+ 0 0 133 -4,-1.7 3,-0.4 -5,-0.3 -2,-0.2 0.949 113.3 46.3 -66.1 -47.8 -27.6 -16.8 -16.1 11 214 A E H <5S+ 0 0 129 -4,-2.6 -2,-0.2 1,-0.2 -1,-0.2 0.906 121.0 38.5 -59.7 -43.0 -28.1 -13.2 -15.2 12 215 A Q H <5S- 0 0 98 -4,-2.7 -1,-0.2 -5,-0.2 -2,-0.2 0.551 99.5-129.8 -86.3 -11.2 -25.9 -12.0 -18.0 13 216 A K T <5 + 0 0 174 -4,-1.1 2,-0.2 -3,-0.4 -3,-0.2 0.975 63.9 141.5 52.8 54.3 -26.9 -14.5 -20.7 14 217 A A < - 0 0 24 -5,-1.8 2,-0.3 -6,-0.1 -1,-0.2 -0.745 45.7-139.0-122.4 169.7 -23.2 -15.1 -21.1 15 218 A I - 0 0 107 231,-0.4 233,-2.2 -2,-0.2 2,-0.2 -0.919 16.7-124.6-128.0 155.2 -20.8 -18.0 -21.7 16 219 A T B -a 248 0A 46 -2,-0.3 233,-0.2 231,-0.2 231,-0.1 -0.601 33.3-101.3 -90.0 157.0 -17.4 -18.8 -20.4 17 220 A A - 0 0 2 231,-2.9 281,-0.3 -2,-0.2 226,-0.1 -0.692 52.0-111.8 -67.6 120.0 -14.2 -19.5 -22.4 18 221 A P > - 0 0 57 0, 0.0 3,-1.9 0, 0.0 4,-0.3 -0.244 16.0-119.0 -56.7 151.9 -14.0 -23.3 -22.4 19 222 A V G > S+ 0 0 81 1,-0.3 3,-2.1 2,-0.2 8,-0.1 0.844 111.4 69.5 -56.4 -36.5 -11.1 -24.9 -20.5 20 223 A S G 3 S+ 0 0 105 1,-0.3 -1,-0.3 7,-0.0 4,-0.1 0.691 88.2 64.5 -57.4 -20.1 -9.9 -26.4 -23.8 21 224 A L G < S+ 0 0 36 -3,-1.9 -1,-0.3 221,-0.1 2,-0.2 0.651 95.7 75.2 -76.4 -17.1 -9.0 -22.9 -25.1 22 225 A F S < S- 0 0 9 -3,-2.1 2,-0.2 -4,-0.3 269,-0.1 -0.594 89.7-105.1 -96.9 155.8 -6.3 -22.6 -22.4 23 226 A Q >> - 0 0 99 267,-0.3 4,-1.5 -2,-0.2 3,-1.2 -0.484 37.5-113.4 -67.9 145.8 -2.9 -24.2 -22.0 24 227 A D H 3> S+ 0 0 139 1,-0.3 4,-2.2 2,-0.2 3,-0.4 0.899 118.3 56.6 -48.2 -41.3 -2.9 -27.0 -19.4 25 228 A S H 34 S+ 0 0 71 1,-0.2 -1,-0.3 2,-0.2 58,-0.1 0.787 107.2 47.9 -67.4 -26.1 -0.6 -24.9 -17.2 26 229 A Q H <4 S+ 0 0 3 -3,-1.2 -1,-0.2 1,-0.1 -2,-0.2 0.747 119.1 40.6 -76.6 -28.2 -3.2 -22.0 -17.2 27 230 A A H < S+ 0 0 17 -4,-1.5 -2,-0.2 -3,-0.4 -3,-0.1 0.706 81.2 112.6 -94.9 -24.9 -6.1 -24.4 -16.4 28 231 A V < + 0 0 30 -4,-2.2 -5,-0.0 -5,-0.2 -4,-0.0 -0.336 26.1 159.2 -66.3 125.4 -4.6 -26.8 -13.8 29 232 A T + 0 0 30 -2,-0.1 -1,-0.2 1,-0.0 -4,-0.0 0.475 57.2 75.6-121.3 -10.7 -6.3 -26.4 -10.4 30 233 A H + 0 0 148 2,-0.1 2,-0.3 274,-0.0 -2,-0.1 0.436 69.6 105.4 -90.6 2.0 -5.7 -29.7 -8.6 31 234 A N S S- 0 0 61 1,-0.0 2,-0.2 32,-0.0 51,-0.1 -0.632 70.1-124.9 -81.6 137.9 -2.0 -29.0 -7.8 32 235 A K - 0 0 164 -2,-0.3 2,-0.9 50,-0.0 -2,-0.1 -0.578 11.1-135.8 -78.6 142.5 -1.1 -28.1 -4.2 33 236 A N + 0 0 25 -2,-0.2 31,-0.1 1,-0.1 29,-0.1 -0.877 26.8 175.1 -96.7 104.3 0.9 -24.9 -3.5 34 237 A G + 0 0 27 -2,-0.9 2,-0.2 95,-0.1 -1,-0.1 0.380 37.6 117.9 -91.8 1.3 3.5 -26.0 -1.0 35 238 A F - 0 0 2 94,-0.1 2,-0.3 90,-0.1 -2,-0.1 -0.486 46.3-165.6 -69.5 141.4 5.3 -22.7 -0.9 36 239 A K > - 0 0 129 -2,-0.2 3,-2.2 23,-0.0 21,-0.3 -0.942 31.1 -80.5-129.5 151.7 5.3 -21.1 2.6 37 240 A L T 3 S+ 0 0 128 -2,-0.3 21,-0.2 1,-0.3 3,-0.1 -0.203 114.5 18.4 -45.7 130.5 6.1 -17.6 3.9 38 241 A G T 3 S+ 0 0 37 19,-2.8 85,-0.3 1,-0.3 -1,-0.3 0.216 84.6 139.3 92.5 -14.0 9.8 -17.0 4.3 39 242 A M < - 0 0 33 -3,-2.2 18,-2.8 18,-0.1 -1,-0.3 -0.389 43.3-140.9 -61.4 141.1 11.0 -19.9 2.0 40 243 A K E +Gh 56 124B 20 83,-2.0 85,-3.0 16,-0.2 50,-0.4 -0.790 31.8 145.5-108.9 151.4 14.0 -18.8 -0.1 41 244 A L E -G 55 0B 0 14,-2.5 14,-2.8 -2,-0.3 2,-0.3 -0.886 40.8 -97.2-161.5-174.4 14.7 -19.6 -3.7 42 245 A E E +GI 54 88B 0 46,-2.8 46,-3.0 -2,-0.3 2,-0.3 -0.862 40.8 158.6-119.2 153.6 16.2 -18.3 -7.0 43 246 A G E -GI 53 87B 0 10,-1.9 10,-2.4 -2,-0.3 44,-0.2 -0.987 40.1 -91.2-167.6 161.3 14.5 -16.8 -9.9 44 247 A I E -G 52 0B 10 42,-2.2 8,-0.2 -2,-0.3 6,-0.1 -0.464 42.8-112.1 -70.9 151.6 14.7 -14.6 -13.0 45 248 A D E > -G 48 0B 27 6,-2.1 3,-2.3 3,-0.6 6,-0.3 -0.788 24.0-149.2 -77.3 113.8 14.1 -10.9 -12.7 46 249 A P T 3 S+ 0 0 48 0, 0.0 -1,-0.2 0, 0.0 -2,-0.0 0.807 98.6 48.5 -60.5 -25.4 10.8 -10.5 -14.7 47 250 A Q T 3 S+ 0 0 160 1,-0.2 -2,-0.0 -3,-0.1 -3,-0.0 0.319 126.1 26.5 -93.9 8.3 11.9 -7.0 -15.7 48 251 A H E X S-G 45 0B 46 -3,-2.3 3,-2.5 3,-0.2 -3,-0.6 -0.404 77.6-174.1-164.3 68.1 15.5 -8.1 -16.7 49 252 A P E 3 S+ 0 0 15 0, 0.0 130,-0.1 0, 0.0 133,-0.1 0.478 75.8 63.4 -66.3 -6.3 15.0 -11.8 -17.7 50 253 A S E 3 S+ 0 0 21 128,-0.3 2,-0.3 131,-0.1 129,-0.1 0.531 94.0 83.0 -84.3 -10.1 18.7 -12.6 -18.3 51 254 A M E < - 0 0 38 -3,-2.5 -6,-2.1 -6,-0.3 2,-0.4 -0.745 63.7-152.7-104.0 144.9 19.4 -12.0 -14.6 52 255 A Y E +G 44 0B 6 47,-0.4 49,-3.0 -2,-0.3 2,-0.3 -0.938 15.9 177.7-117.4 137.1 19.0 -14.2 -11.5 53 256 A F E -Gj 43 101B 30 -10,-2.4 -10,-1.9 -2,-0.4 2,-0.5 -0.905 36.0-102.3-130.5 159.9 18.3 -13.1 -7.9 54 257 A I E -G 42 0B 3 47,-0.6 16,-1.5 -2,-0.3 2,-0.3 -0.731 45.8-167.8 -77.7 130.1 17.7 -14.6 -4.5 55 258 A L E -GK 41 69B 0 -14,-2.8 -14,-2.5 -2,-0.5 2,-0.4 -0.920 14.6-152.5-126.0 147.5 14.0 -14.4 -3.7 56 259 A T E -GK 40 68B 20 12,-2.3 12,-2.5 -2,-0.3 2,-0.7 -0.929 28.9-113.5-115.5 141.3 11.8 -14.9 -0.6 57 260 A V E + K 0 67B 2 -18,-2.8 -19,-2.8 -2,-0.4 10,-0.2 -0.655 38.0 174.3 -70.5 113.6 8.2 -16.0 -0.5 58 261 A A E + 0 0 29 8,-3.2 2,-0.3 -2,-0.7 9,-0.2 0.632 63.6 1.9 -96.4 -20.0 6.5 -12.8 0.9 59 262 A E E - K 0 66B 72 7,-1.2 7,-2.3 -23,-0.1 2,-0.4 -0.958 58.0-151.0-166.2 146.3 2.9 -14.0 0.6 60 263 A V E + K 0 65B 54 -2,-0.3 2,-0.3 5,-0.2 5,-0.2 -0.991 17.1 171.6-125.1 138.1 0.9 -17.1 -0.5 61 264 A C E > - K 0 64B 26 3,-2.6 3,-2.5 -2,-0.4 245,-0.2 -0.878 60.7 -56.5-149.2 108.4 -2.6 -16.9 -2.0 62 265 A G T 3 S- 0 0 22 243,-0.5 243,-0.1 -2,-0.3 -1,-0.1 -0.338 122.3 -15.4 58.6-125.7 -4.2 -19.9 -3.5 63 266 A Y T 3 S+ 0 0 14 -3,-0.1 19,-3.0 -2,-0.1 20,-0.3 0.176 126.6 83.8 -95.0 15.1 -1.9 -21.2 -6.2 64 267 A R E < -KL 61 81B 0 -3,-2.5 -3,-2.6 17,-0.3 2,-0.3 -0.784 55.1-165.4-116.1 162.4 0.0 -18.0 -6.3 65 268 A L E -KL 60 80B 0 15,-2.7 15,-2.8 -2,-0.3 2,-0.5 -0.997 18.3-133.7-145.8 146.6 2.9 -16.4 -4.4 66 269 A R E -KL 59 79B 56 -7,-2.3 -8,-3.2 -2,-0.3 -7,-1.2 -0.887 26.4-153.4 -97.8 128.6 4.4 -13.0 -4.0 67 270 A L E -KL 57 78B 0 11,-3.3 11,-2.0 -2,-0.5 2,-0.4 -0.854 4.3-156.7-108.2 141.6 8.2 -13.0 -4.3 68 271 A H E -K 56 0B 40 -12,-2.5 -12,-2.3 -2,-0.4 2,-1.0 -0.929 21.4-124.2-117.4 134.5 10.5 -10.4 -2.7 69 272 A F E > -K 55 0B 10 -2,-0.4 3,-2.5 4,-0.3 -14,-0.2 -0.716 41.6-114.2 -78.0 106.7 14.1 -9.6 -3.9 70 273 A D T 3 S+ 0 0 5 -16,-1.5 34,-1.2 -2,-1.0 -16,-0.2 -0.052 94.5 6.0 -44.8 126.1 16.2 -10.2 -0.8 71 274 A G T 3 S+ 0 0 50 1,-0.3 -1,-0.3 32,-0.2 2,-0.1 0.143 112.1 97.5 91.8 -20.5 17.7 -7.0 0.5 72 275 A Y S < S- 0 0 82 -3,-2.5 -1,-0.3 1,-0.2 2,-0.0 -0.380 83.0 -69.0-103.6 174.9 15.9 -4.7 -2.0 73 276 A S > - 0 0 67 1,-0.1 3,-1.5 -2,-0.1 -4,-0.3 -0.293 33.4-127.5 -63.6 145.6 12.8 -2.5 -1.9 74 277 A E G > S+ 0 0 142 1,-0.3 3,-2.0 2,-0.2 -1,-0.1 0.636 100.4 84.2 -62.5 -17.4 9.3 -4.1 -1.7 75 278 A C G 3 S+ 0 0 100 1,-0.3 -1,-0.3 -7,-0.0 -2,-0.0 0.740 87.6 53.5 -59.6 -23.3 8.5 -2.0 -4.7 76 279 A H G < S+ 0 0 101 -3,-1.5 -1,-0.3 -7,-0.1 -2,-0.2 0.451 79.3 126.8 -89.4 -3.7 10.0 -4.7 -6.9 77 280 A D < - 0 0 31 -3,-2.0 2,-0.3 -4,-0.1 -9,-0.2 -0.224 38.4-175.3 -55.6 146.9 7.9 -7.6 -5.3 78 281 A F E -L 67 0B 33 -11,-2.0 -11,-3.3 179,-0.0 2,-0.4 -0.970 20.8-120.7-147.0 157.9 6.0 -9.6 -8.0 79 282 A W E +L 66 0B 28 -2,-0.3 2,-0.3 -13,-0.2 -13,-0.2 -0.820 28.3 170.5-104.5 139.1 3.5 -12.4 -8.2 80 283 A V E -L 65 0B 14 -15,-2.8 -15,-2.7 -2,-0.4 2,-0.2 -0.911 34.3-108.6-133.2 164.4 3.9 -15.8 -9.8 81 284 A N E > -L 64 0B 6 -2,-0.3 3,-2.2 -17,-0.2 -17,-0.3 -0.618 35.3-112.5 -83.1 156.6 1.9 -19.1 -9.9 82 285 A A T 3 S+ 0 0 7 -19,-3.0 49,-0.3 1,-0.3 -18,-0.1 0.714 118.6 55.8 -65.8 -18.3 3.3 -22.1 -8.1 83 286 A N T 3 S+ 0 0 26 -20,-0.3 -1,-0.3 -58,-0.1 -19,-0.1 0.174 78.3 141.5 -96.1 17.2 3.9 -23.8 -11.5 84 287 A S < - 0 0 13 -3,-2.2 3,-0.5 1,-0.1 47,-0.4 -0.335 45.4-153.9 -57.2 136.5 6.0 -20.9 -12.8 85 288 A P S S+ 0 0 47 0, 0.0 -1,-0.1 0, 0.0 -3,-0.0 0.421 85.6 77.9 -85.7 -1.1 9.0 -22.0 -14.9 86 289 A D S S+ 0 0 44 -43,-0.1 -42,-2.2 -42,-0.0 2,-0.3 0.280 84.5 68.3 -93.6 8.5 10.8 -18.7 -13.9 87 290 A I E -I 43 0B 2 -3,-0.5 45,-0.4 -44,-0.2 -44,-0.3 -0.905 59.4-173.4-129.2 154.5 11.8 -19.8 -10.4 88 291 A H E -I 42 0B 4 -46,-3.0 -46,-2.8 -2,-0.3 3,-0.1 -0.963 29.0 -95.4-146.9 154.5 14.3 -22.5 -9.3 89 292 A P > - 0 0 17 0, 0.0 3,-2.2 0, 0.0 4,-0.2 -0.381 55.5 -79.5 -73.4 156.9 15.4 -24.1 -6.1 90 293 A A T 3 S+ 0 0 17 -50,-0.4 37,-0.1 35,-0.4 34,-0.0 -0.246 120.8 32.7 -49.2 133.7 18.4 -22.9 -4.1 91 294 A G T 3> S+ 0 0 13 -3,-0.1 4,-2.4 -50,-0.0 -1,-0.3 0.234 84.2 113.0 98.5 -11.0 21.6 -24.3 -5.7 92 295 A W H <> S+ 0 0 24 -3,-2.2 4,-1.7 1,-0.2 6,-0.2 0.912 74.9 48.8 -62.2 -45.1 20.2 -24.1 -9.2 93 296 A F H >>S+ 0 0 24 -4,-0.2 5,-2.1 1,-0.2 4,-0.9 0.911 113.7 46.4 -64.7 -40.7 22.6 -21.4 -10.5 94 297 A E H 45S+ 0 0 145 1,-0.2 3,-0.5 2,-0.2 -1,-0.2 0.917 114.2 48.7 -65.4 -43.6 25.7 -23.1 -9.1 95 298 A K H <5S+ 0 0 151 -4,-2.4 -1,-0.2 1,-0.2 -2,-0.2 0.776 119.3 37.1 -64.8 -29.4 24.6 -26.5 -10.6 96 299 A T H <5S- 0 0 66 -4,-1.7 -1,-0.2 -5,-0.2 -2,-0.2 0.393 111.9-109.6-111.7 1.8 23.8 -25.1 -14.0 97 300 A G T <5 + 0 0 71 -4,-0.9 -3,-0.2 -3,-0.5 2,-0.2 0.714 66.8 143.8 78.6 23.8 26.6 -22.5 -14.4 98 301 A H < - 0 0 35 -5,-2.1 2,-0.3 -6,-0.2 -1,-0.2 -0.529 48.3-115.4 -90.8 162.4 24.5 -19.3 -14.1 99 302 A K - 0 0 130 -2,-0.2 -47,-0.4 2,-0.0 2,-0.4 -0.745 23.0-142.2 -96.5 144.3 25.5 -16.1 -12.4 100 303 A L - 0 0 2 -2,-0.3 -47,-0.2 -49,-0.1 11,-0.1 -0.880 8.6-145.8-106.3 137.8 23.8 -14.7 -9.3 101 304 A Q B -j 53 0B 50 -49,-3.0 -47,-0.6 -2,-0.4 3,-0.1 -0.922 39.2-137.1 -90.6 108.5 23.0 -11.0 -8.6 102 305 A P - 0 0 15 0, 0.0 3,-0.1 0, 0.0 6,-0.1 -0.134 25.0 -78.1 -71.5 165.2 23.5 -11.3 -4.8 103 306 A P > - 0 0 4 0, 0.0 3,-2.3 0, 0.0 -32,-0.2 -0.166 67.4 -75.7 -55.7 153.9 21.2 -9.7 -2.1 104 307 A K T 3 S+ 0 0 137 -34,-1.2 3,-0.1 1,-0.3 -32,-0.0 -0.308 124.5 27.6 -54.8 134.2 21.7 -6.0 -1.5 105 308 A G T 3 S+ 0 0 72 1,-0.3 -1,-0.3 -3,-0.1 2,-0.2 -0.081 101.5 108.6 103.7 -29.8 24.9 -5.5 0.5 106 309 A Y < - 0 0 82 -3,-2.3 -1,-0.3 2,-0.0 2,-0.3 -0.524 62.1-137.0 -89.5 143.7 26.6 -8.7 -0.8 107 310 A K - 0 0 139 -2,-0.2 3,-0.1 -3,-0.1 4,-0.1 -0.701 25.5-124.9 -86.4 151.5 29.5 -9.2 -3.2 108 311 A E S > S+ 0 0 74 -2,-0.3 3,-1.2 1,-0.2 -1,-0.1 0.872 104.8 49.3 -69.7 -43.3 28.9 -12.0 -5.7 109 312 A E T 3 S+ 0 0 200 1,-0.3 -1,-0.2 -7,-0.0 -3,-0.0 0.756 106.6 58.4 -70.7 -24.9 32.0 -14.2 -5.1 110 313 A E T 3 S+ 0 0 118 -3,-0.1 2,-0.4 2,-0.0 -1,-0.3 0.406 80.7 117.2 -83.4 1.5 31.3 -14.2 -1.3 111 314 A F < + 0 0 20 -3,-1.2 2,-0.4 -4,-0.1 -11,-0.0 -0.598 33.0 166.8 -81.2 127.1 27.7 -15.7 -1.7 112 315 A S > - 0 0 44 -2,-0.4 4,-2.9 1,-0.1 5,-0.2 -0.990 31.0-149.7-137.8 122.3 27.1 -19.1 -0.2 113 316 A W H > S+ 0 0 31 -2,-0.4 4,-3.0 2,-0.2 5,-0.3 0.913 100.0 53.7 -56.2 -44.2 23.6 -20.6 0.2 114 317 A S H > S+ 0 0 75 1,-0.2 4,-1.4 2,-0.2 -1,-0.2 0.932 114.9 39.5 -59.9 -45.5 24.7 -22.5 3.4 115 318 A Q H > S+ 0 0 87 2,-0.2 4,-3.0 1,-0.2 -1,-0.2 0.889 114.4 53.9 -71.2 -40.2 26.0 -19.3 5.1 116 319 A Y H X S+ 0 0 15 -4,-2.9 4,-2.3 1,-0.2 -2,-0.2 0.929 108.7 48.3 -60.6 -46.6 23.1 -17.2 3.8 117 320 A L H X>S+ 0 0 40 -4,-3.0 5,-1.7 2,-0.2 4,-0.9 0.851 112.8 50.0 -61.5 -34.5 20.5 -19.6 5.3 118 321 A R H ><5S+ 0 0 143 -4,-1.4 3,-0.7 -5,-0.3 -2,-0.2 0.968 111.7 46.9 -64.3 -53.4 22.5 -19.5 8.5 119 322 A S H 3<5S+ 0 0 68 -4,-3.0 -2,-0.2 1,-0.2 -1,-0.2 0.818 121.0 37.5 -57.4 -38.5 22.6 -15.7 8.7 120 323 A T H 3<5S- 0 0 53 -4,-2.3 -1,-0.2 -5,-0.2 -2,-0.2 0.508 99.4-133.3 -94.8 -7.4 18.9 -15.4 7.8 121 324 A R T <<5 + 0 0 230 -4,-0.9 2,-0.2 -3,-0.7 -3,-0.2 0.902 62.6 137.4 53.0 46.1 17.8 -18.4 9.9 122 325 A A < - 0 0 25 -5,-1.7 2,-0.4 -6,-0.2 -1,-0.2 -0.673 51.9-129.3-120.5 164.3 15.8 -19.4 6.9 123 326 A Q - 0 0 160 -85,-0.3 -83,-2.0 -2,-0.2 2,-0.3 -0.933 21.7-122.0-116.2 144.9 14.9 -22.5 4.9 124 327 A A B -h 40 0B 30 -2,-0.4 -83,-0.2 -85,-0.2 -85,-0.1 -0.586 38.8 -99.7 -76.2 142.1 15.2 -23.0 1.2 125 328 A A - 0 0 3 -85,-3.0 -35,-0.4 -2,-0.3 -1,-0.1 -0.466 51.6-102.4 -57.1 129.7 12.0 -23.9 -0.6 126 329 A P > - 0 0 52 0, 0.0 3,-1.6 0, 0.0 4,-0.2 -0.281 23.6-121.7 -60.0 145.6 12.3 -27.8 -1.1 127 330 A K G > S+ 0 0 138 1,-0.3 3,-2.1 2,-0.2 -2,-0.1 0.788 103.9 72.9 -55.2 -35.9 13.2 -28.9 -4.6 128 331 A H G 3 S+ 0 0 160 1,-0.3 -1,-0.3 3,-0.0 -3,-0.0 0.699 88.8 64.7 -61.4 -17.4 10.1 -31.0 -5.1 129 332 A L G < S+ 0 0 29 -3,-1.6 2,-0.5 -95,-0.1 -1,-0.3 0.728 84.4 92.4 -71.0 -23.8 8.1 -27.8 -5.6 130 333 A F < - 0 0 25 -3,-2.1 -47,-0.1 -4,-0.2 -42,-0.1 -0.632 50.3-168.6 -95.5 122.7 9.9 -26.6 -8.7 131 334 A V 0 0 94 -2,-0.5 -1,-0.1 -47,-0.4 -43,-0.1 0.774 360.0 360.0 -66.6 -25.0 8.8 -27.3 -12.4 132 335 A S 0 0 26 -45,-0.4 -1,-0.1 -48,-0.4 -2,-0.0 -0.928 360.0 360.0-121.5 360.0 12.2 -26.0 -13.6 133 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 134 340 A P 0 0 127 0, 0.0 3,-0.1 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 125.2 13.3 -31.9 -22.6 135 341 A P - 0 0 98 0, 0.0 2,-1.0 0, 0.0 32,-0.2 0.003 360.0 -96.1 -45.2 150.8 15.4 -29.3 -24.5 136 342 A P > - 0 0 7 0, 0.0 3,-2.3 0, 0.0 32,-0.0 -0.667 52.5-119.2 -70.5 103.5 13.8 -27.1 -27.2 137 343 A L T 3 S+ 0 0 124 -2,-1.0 3,-0.1 1,-0.3 30,-0.0 -0.188 90.2 8.7 -51.6 124.8 14.7 -29.3 -30.2 138 344 A G T 3 S+ 0 0 17 1,-0.2 2,-0.6 92,-0.0 -1,-0.3 0.345 99.8 110.0 89.4 -6.2 16.9 -27.4 -32.7 139 345 A F < + 0 0 6 -3,-2.3 2,-0.3 91,-0.1 -1,-0.2 -0.904 40.3 165.4-106.4 113.2 17.5 -24.3 -30.5 140 346 A Q > - 0 0 134 -2,-0.6 3,-2.1 -3,-0.1 21,-0.3 -0.920 45.8 -88.4-125.1 150.3 21.1 -24.0 -29.2 141 347 A V T 3 S+ 0 0 86 -2,-0.3 21,-0.2 1,-0.3 3,-0.1 -0.276 113.4 28.4 -53.6 132.4 23.0 -21.1 -27.6 142 348 A G T 3 S+ 0 0 38 19,-3.2 -1,-0.3 1,-0.4 86,-0.1 0.155 87.0 125.8 102.1 -17.7 24.6 -19.0 -30.3 143 349 A M < - 0 0 27 -3,-2.1 18,-2.8 84,-0.1 -1,-0.4 -0.408 52.6-131.5 -71.9 153.2 22.2 -19.7 -33.1 144 350 A K E +Mn 160 229C 19 84,-2.5 86,-2.8 16,-0.2 50,-0.4 -0.708 32.4 151.4-109.7 155.3 20.6 -16.7 -34.9 145 351 A L E -M 159 0C 0 14,-2.4 14,-2.6 -2,-0.3 2,-0.4 -0.929 43.5 -94.4-158.8-179.3 17.0 -15.9 -35.8 146 352 A E E +MO 158 192C 2 46,-2.8 46,-2.6 -2,-0.3 2,-0.3 -0.933 44.9 179.4-109.0 134.7 14.6 -13.0 -36.4 147 353 A A E -MO 157 191C 0 10,-2.5 10,-3.0 -2,-0.4 2,-0.4 -0.984 31.6-113.8-141.3 150.4 12.4 -11.9 -33.5 148 354 A V E -M 156 0C 18 42,-3.0 2,-0.8 -2,-0.3 8,-0.2 -0.655 32.2-127.9 -74.3 126.1 9.7 -9.3 -32.5 149 355 A D E > -M 152 0C 12 6,-2.1 3,-1.1 3,-0.5 6,-0.3 -0.711 15.3-157.4 -73.0 109.7 10.9 -6.8 -30.0 150 356 A R T 3 S+ 0 0 76 -2,-0.8 -1,-0.2 30,-0.3 31,-0.1 0.761 94.6 52.8 -62.6 -24.2 8.2 -7.0 -27.3 151 357 A M T 3 S+ 0 0 123 1,-0.3 -1,-0.3 29,-0.2 -2,-0.1 0.674 125.6 25.1 -84.3 -16.2 9.2 -3.5 -26.1 152 358 A N E X S-M 149 0C 71 -3,-1.1 3,-2.3 3,-0.2 -3,-0.5 -0.616 78.3-176.9-143.7 75.1 8.8 -2.2 -29.8 153 359 A P E 3 S+ 0 0 95 0, 0.0 -3,-0.1 0, 0.0 -2,-0.1 0.507 74.8 64.5 -67.6 -11.1 6.3 -4.7 -31.4 154 360 A S E 3 S+ 0 0 88 -6,-0.1 2,-0.5 -5,-0.1 -4,-0.1 0.562 91.2 86.9 -81.0 -9.3 6.4 -3.2 -34.9 155 361 A L E < - 0 0 62 -3,-2.3 -6,-2.1 -6,-0.3 2,-0.5 -0.819 57.2-167.0-101.2 127.0 10.1 -4.2 -35.2 156 362 A V E -Mp 148 204C 5 47,-0.6 49,-2.9 -2,-0.5 2,-0.3 -0.945 28.7-169.5-108.0 132.4 11.4 -7.6 -36.3 157 363 A C E -Mp 147 205C 4 -10,-3.0 -10,-2.5 -2,-0.5 2,-0.3 -0.873 32.7 -96.7-134.5 152.8 15.0 -7.8 -35.4 158 364 A V E +M 146 0C 0 47,-2.9 16,-1.4 -2,-0.3 2,-0.3 -0.502 58.3 168.8 -62.9 124.8 18.3 -9.7 -35.7 159 365 A A E -MQ 145 173C 0 -14,-2.6 -14,-2.4 -2,-0.3 2,-0.3 -0.887 26.1-148.0-143.1 166.0 18.5 -11.8 -32.6 160 366 A S E -MQ 144 172C 10 12,-2.7 12,-2.6 -2,-0.3 2,-0.6 -0.952 25.4-116.5-134.3 151.7 20.4 -14.7 -31.0 161 367 A V E + Q 0 171C 1 -18,-2.8 -19,-3.2 -2,-0.3 10,-0.2 -0.824 35.5 174.3 -83.1 121.8 19.6 -17.6 -28.6 162 368 A T E + 0 0 53 8,-2.7 2,-0.3 -2,-0.6 -1,-0.1 0.535 58.8 10.3-111.7 -6.5 21.7 -16.8 -25.5 163 369 A D E - Q 0 170C 37 7,-0.7 7,-2.3 -23,-0.1 2,-0.4 -0.977 52.6-153.5-162.7 158.1 20.6 -19.5 -23.2 164 370 A V E + Q 0 169C 44 -2,-0.3 2,-0.4 5,-0.2 5,-0.2 -0.988 15.0 176.0-134.7 124.8 18.6 -22.7 -22.9 165 371 A V E > - Q 0 168C 16 3,-2.4 3,-2.3 -2,-0.4 2,-0.0 -0.973 61.5 -55.0-133.3 115.5 17.0 -23.8 -19.7 166 372 A D T 3 S- 0 0 85 -2,-0.4 -34,-0.1 1,-0.3 0, 0.0 -0.310 123.4 -11.0 50.0-119.0 14.8 -26.9 -19.7 167 373 A S T 3 S+ 0 0 56 -32,-0.2 2,-0.3 -3,-0.1 -1,-0.3 0.386 126.3 69.5 -92.3 4.6 12.1 -26.4 -22.5 168 374 A R E < -Q 165 0C 66 -3,-2.3 -3,-2.4 17,-0.1 2,-0.3 -0.787 58.9-155.4-122.8 164.1 12.8 -22.8 -23.1 169 375 A F E -QR 164 184C 0 15,-2.5 15,-2.5 -2,-0.3 2,-0.6 -0.964 22.2-115.7-139.4 157.4 15.4 -20.5 -24.5 170 376 A L E -QR 163 183C 8 -7,-2.3 -8,-2.7 -2,-0.3 -7,-0.7 -0.825 22.6-149.7 -98.7 120.5 16.4 -16.8 -24.1 171 377 A V E -QR 161 182C 0 11,-3.0 11,-1.7 -2,-0.6 2,-0.4 -0.794 17.6-173.0 -92.1 126.9 16.0 -14.5 -27.1 172 378 A H E -Q 160 0C 35 -12,-2.6 -12,-2.7 -2,-0.5 2,-0.6 -0.951 23.6-129.5-126.2 138.9 18.5 -11.7 -27.2 173 379 A F E > -Q 159 0C 3 -2,-0.4 3,-2.6 4,-0.3 -14,-0.2 -0.792 42.3-104.4 -94.0 119.4 18.7 -8.7 -29.6 174 380 A D T 3 S- 0 0 7 -16,-1.4 34,-1.6 -2,-0.6 3,-0.1 -0.172 94.7 -9.7 -57.1 124.8 22.2 -8.5 -31.0 175 381 A N T 3 S+ 0 0 106 1,-0.3 -1,-0.3 32,-0.2 2,-0.2 0.551 110.2 116.4 66.8 12.8 24.3 -5.7 -29.5 176 382 A W S < S- 0 0 83 -3,-2.6 -1,-0.3 1,-0.1 -3,-0.1 -0.654 79.8 -70.6-102.0 164.1 21.2 -4.3 -27.7 177 383 A D > - 0 0 94 -2,-0.2 3,-1.8 1,-0.1 -4,-0.3 -0.239 39.1-130.2 -45.5 131.0 20.5 -3.9 -24.0 178 384 A D G > S+ 0 0 54 1,-0.3 3,-1.4 2,-0.2 -128,-0.3 0.608 100.0 82.2 -67.1 -5.0 19.9 -7.3 -22.4 179 385 A T G 3 S+ 0 0 58 1,-0.2 -1,-0.3 -131,-0.1 -2,-0.1 0.612 83.1 61.3 -73.7 -6.5 16.7 -5.8 -20.8 180 386 A Y G < S+ 0 0 73 -3,-1.8 -30,-0.3 -7,-0.1 -1,-0.2 0.503 83.2 114.8 -89.7 -5.3 15.0 -6.5 -24.2 181 387 A D < - 0 0 9 -3,-1.4 2,-0.3 -4,-0.1 -9,-0.2 -0.246 42.8-178.9 -59.5 147.6 15.6 -10.3 -23.7 182 388 A Y E -R 171 0C 16 -11,-1.7 -11,-3.0 -134,-0.1 2,-0.2 -0.992 27.5-112.9-149.1 153.6 12.7 -12.6 -23.3 183 389 A W E +R 170 0C 27 -2,-0.3 2,-0.3 -13,-0.2 -13,-0.2 -0.595 42.5 168.4 -85.5 148.4 12.2 -16.3 -22.7 184 390 A C E -R 169 0C 4 -15,-2.5 -15,-2.5 -2,-0.2 -1,-0.0 -0.883 26.9-141.5-151.3 160.2 10.6 -18.3 -25.4 185 391 A D > - 0 0 48 -2,-0.3 3,-2.3 -17,-0.2 -17,-0.1 -0.861 43.8 -93.2-128.8 170.7 9.7 -21.8 -26.8 186 392 A P T 3 S+ 0 0 26 0, 0.0 50,-2.2 0, 0.0 5,-0.1 0.659 121.0 57.1 -56.9 -18.2 9.7 -23.2 -30.4 187 393 A S T 3 S+ 0 0 30 48,-0.2 51,-0.9 50,-0.1 48,-0.1 0.399 75.1 132.0 -93.2 -0.1 6.0 -22.4 -30.8 188 394 A S X - 0 0 11 -3,-2.3 3,-1.2 1,-0.2 -4,-0.0 -0.294 51.6-149.6 -58.8 128.2 6.3 -18.7 -30.1 189 395 A P T 3 S+ 0 0 35 0, 0.0 -1,-0.2 0, 0.0 48,-0.0 0.512 92.3 69.8 -71.1 -0.9 4.6 -16.4 -32.7 190 396 A Y T 3 S+ 0 0 37 -42,-0.1 -42,-3.0 -43,-0.1 2,-0.3 0.411 90.9 68.2 -97.0 -1.0 7.2 -13.8 -31.9 191 397 A I E < +O 147 0C 7 -3,-1.2 -44,-0.2 -44,-0.2 -35,-0.0 -0.886 54.5 173.4-123.9 154.1 10.1 -15.6 -33.5 192 398 A H E -O 146 0C 33 -46,-2.6 -46,-2.8 -2,-0.3 3,-0.1 -0.981 34.8 -89.9-152.3 158.1 11.0 -16.5 -37.2 193 399 A P > - 0 0 24 0, 0.0 3,-2.1 0, 0.0 4,-0.3 -0.265 57.3 -79.7 -69.7 157.5 13.9 -18.1 -39.2 194 400 A V T 3 S+ 0 0 34 36,-0.4 38,-0.1 -50,-0.4 35,-0.0 -0.356 121.5 28.4 -49.1 129.3 16.7 -16.1 -40.7 195 401 A G T 3> S+ 0 0 8 -3,-0.1 4,-2.1 -50,-0.0 -1,-0.3 0.300 81.7 117.8 96.6 -6.7 15.3 -14.5 -43.9 196 402 A W H <> S+ 0 0 62 -3,-2.1 4,-2.1 1,-0.2 5,-0.2 0.909 75.6 50.8 -58.2 -47.2 11.6 -14.3 -42.9 197 403 A C H >>S+ 0 0 2 -4,-0.3 5,-2.3 2,-0.2 4,-1.0 0.934 109.6 49.9 -56.7 -49.5 11.5 -10.5 -43.2 198 404 A Q H >45S+ 0 0 175 1,-0.2 3,-0.6 2,-0.2 -1,-0.2 0.904 112.8 47.4 -56.3 -44.7 13.0 -10.6 -46.7 199 405 A K H 3<5S+ 0 0 170 -4,-2.1 -1,-0.2 1,-0.2 -2,-0.2 0.821 115.8 45.1 -65.8 -33.6 10.4 -13.2 -47.7 200 406 A Q H 3<5S- 0 0 121 -4,-2.1 -1,-0.2 -5,-0.2 -2,-0.2 0.502 108.4-122.3 -87.6 -6.5 7.6 -11.2 -46.1 201 407 A G T <<5 + 0 0 72 -4,-1.0 -3,-0.2 -3,-0.6 -4,-0.1 0.838 67.9 136.0 63.7 33.7 8.7 -7.8 -47.6 202 408 A K < - 0 0 86 -5,-2.3 -1,-0.3 -6,-0.2 -2,-0.1 -0.864 61.2-100.7-111.2 145.9 9.0 -6.4 -44.0 203 409 A P - 0 0 105 0, 0.0 -47,-0.6 0, 0.0 2,-0.5 -0.375 31.5-144.3 -66.4 143.8 11.9 -4.3 -42.7 204 410 A L E -p 156 0C 46 -49,-0.1 -47,-0.2 12,-0.1 12,-0.1 -0.950 6.9-138.1-110.8 127.6 14.6 -6.0 -40.5 205 411 A T E -p 157 0C 33 -49,-2.9 -47,-2.9 -2,-0.5 3,-0.1 -0.769 24.3-149.7 -82.6 113.2 16.2 -4.2 -37.7 206 412 A P - 0 0 23 0, 0.0 3,-0.1 0, 0.0 4,-0.0 -0.132 37.7 -63.8 -73.3 173.3 20.0 -5.0 -37.7 207 413 A P S > S- 0 0 7 0, 0.0 3,-2.1 0, 0.0 -32,-0.2 -0.239 73.7 -79.7 -54.6 149.5 22.2 -5.2 -34.6 208 414 A Q T 3 S+ 0 0 67 -34,-1.6 -3,-0.0 1,-0.3 -32,-0.0 -0.231 114.4 1.8 -56.7 135.3 22.6 -1.9 -32.8 209 415 A D T 3 S+ 0 0 138 1,-0.2 -1,-0.3 -3,-0.1 3,-0.1 0.642 84.4 174.7 62.4 17.4 25.1 0.4 -34.5 210 416 A Y < - 0 0 31 -3,-2.1 -1,-0.2 1,-0.1 6,-0.1 -0.399 42.2-105.0 -56.6 122.0 25.7 -2.1 -37.3 211 417 A P S S+ 0 0 105 0, 0.0 -1,-0.1 0, 0.0 4,-0.1 -0.272 101.3 1.4 -55.5 127.3 28.1 -0.3 -39.8 212 418 A D S > S- 0 0 103 1,-0.1 3,-1.6 2,-0.1 -2,-0.1 0.973 80.6-168.4 55.3 64.5 26.1 0.7 -42.9 213 419 A P G > S+ 0 0 70 0, 0.0 3,-0.9 0, 0.0 -1,-0.1 0.631 77.0 63.9 -64.0 -18.1 22.8 -0.7 -41.4 214 420 A D G 3 S+ 0 0 153 1,-0.2 -2,-0.1 -8,-0.0 0, 0.0 0.809 104.4 47.1 -74.3 -30.5 20.9 -0.4 -44.8 215 421 A N G < S+ 0 0 116 -3,-1.6 -1,-0.2 -4,-0.1 2,-0.1 0.064 78.6 146.7 -99.6 23.2 23.2 -2.9 -46.4 216 422 A F < - 0 0 31 -3,-0.9 2,-0.4 -12,-0.1 -12,-0.1 -0.424 27.9-168.9 -57.2 133.2 23.0 -5.4 -43.5 217 423 A C > - 0 0 61 1,-0.1 4,-2.6 -2,-0.1 5,-0.2 -0.990 22.3-149.9-134.9 119.9 23.2 -8.9 -45.0 218 424 A W H > S+ 0 0 28 -2,-0.4 4,-3.2 1,-0.2 5,-0.3 0.909 98.3 53.3 -56.6 -45.7 22.5 -12.1 -43.1 219 425 A E H > S+ 0 0 150 1,-0.2 4,-1.8 2,-0.2 -1,-0.2 0.915 113.7 43.1 -60.8 -42.0 24.9 -14.2 -45.1 220 426 A K H > S+ 0 0 96 2,-0.2 4,-3.2 1,-0.2 -1,-0.2 0.892 114.2 51.0 -65.2 -42.3 27.7 -11.8 -44.4 221 427 A Y H X S+ 0 0 25 -4,-2.6 4,-2.3 2,-0.2 6,-0.3 0.894 110.4 48.3 -65.3 -41.1 26.7 -11.4 -40.8 222 428 A L H X>S+ 0 0 24 -4,-3.2 4,-1.6 2,-0.2 5,-0.6 0.880 113.8 48.1 -66.1 -36.9 26.7 -15.2 -40.3 223 429 A E H <5S+ 0 0 146 -4,-1.8 -2,-0.2 -5,-0.3 -1,-0.2 0.935 111.8 50.0 -65.4 -46.5 30.1 -15.3 -42.0 224 430 A E H <5S+ 0 0 99 -4,-3.2 -2,-0.2 1,-0.2 -1,-0.2 0.891 122.6 31.0 -55.7 -44.9 31.4 -12.5 -39.7 225 431 A T H <5S- 0 0 63 -4,-2.3 -1,-0.2 -5,-0.1 -2,-0.2 0.606 96.5-133.8 -91.8 -16.6 30.2 -14.2 -36.5 226 432 A G T <5 + 0 0 67 -4,-1.6 2,-0.2 1,-0.2 -3,-0.2 0.659 58.4 144.4 62.0 18.5 30.6 -17.8 -37.6 227 433 A A < - 0 0 22 -5,-0.6 2,-0.3 -6,-0.3 -1,-0.2 -0.532 45.6-131.4 -85.8 155.7 27.1 -18.4 -36.2 228 434 A S - 0 0 82 -2,-0.2 -84,-2.5 -86,-0.1 2,-0.3 -0.728 20.5-116.6 -97.0 151.8 24.5 -20.8 -37.5 229 435 A A B -n 144 0C 35 -2,-0.3 -84,-0.2 -86,-0.2 -86,-0.1 -0.665 38.2-100.6 -77.5 143.6 20.8 -19.9 -38.1 230 436 A V - 0 0 2 -86,-2.8 -36,-0.4 -2,-0.3 -91,-0.1 -0.461 54.3-105.1 -54.8 128.7 18.3 -21.8 -36.1 231 437 A P > - 0 0 38 0, 0.0 3,-1.9 0, 0.0 4,-0.4 -0.377 18.8-123.1 -65.1 144.6 17.1 -24.3 -38.7 232 438 A T G > S+ 0 0 103 1,-0.3 3,-1.6 2,-0.2 -2,-0.1 0.854 108.6 65.7 -52.9 -38.8 13.7 -23.7 -40.2 233 439 A W G 3 S+ 0 0 156 1,-0.3 -1,-0.3 3,-0.1 -3,-0.0 0.746 91.3 64.7 -56.5 -23.2 12.5 -27.2 -39.0 234 440 A A G < S+ 0 0 1 -3,-1.9 2,-0.5 -96,-0.2 -1,-0.3 0.711 79.6 92.0 -75.9 -23.5 12.8 -26.1 -35.4 235 441 A F < - 0 0 32 -3,-1.6 2,-0.6 -4,-0.4 -48,-0.2 -0.671 58.1-168.4 -81.3 119.1 10.1 -23.4 -35.6 236 442 A K - 0 0 109 -50,-2.2 -1,-0.1 -2,-0.5 -3,-0.1 -0.732 15.9-141.7-114.8 78.0 6.7 -25.0 -34.6 237 443 A V - 0 0 142 -2,-0.6 -49,-0.1 1,-0.1 -50,-0.1 -0.035 12.7-142.9 -34.4 115.8 3.9 -22.5 -35.5 238 444 A R - 0 0 51 -51,-0.9 -1,-0.1 1,-0.1 3,-0.1 -0.702 23.5-109.7 -85.9 144.1 1.2 -22.5 -32.9 239 445 A P - 0 0 102 0, 0.0 3,-0.1 0, 0.0 -1,-0.1 -0.339 40.2 -90.9 -69.1 154.0 -2.3 -22.2 -34.2 240 446 A P - 0 0 68 0, 0.0 31,-0.2 0, 0.0 30,-0.1 -0.343 52.4-105.7 -54.0 144.2 -4.3 -18.9 -33.6 241 447 A H - 0 0 36 29,-1.9 31,-0.1 28,-0.2 -219,-0.1 -0.239 18.7-134.3 -65.5 168.0 -6.2 -19.2 -30.3 242 448 A S + 0 0 77 -221,-0.2 2,-0.2 -3,-0.1 -1,-0.1 0.055 52.4 137.3-117.7 25.4 -10.0 -19.7 -30.4 243 449 A F - 0 0 4 -222,-0.1 2,-0.3 -226,-0.1 -226,-0.0 -0.535 40.0-152.5 -67.3 138.4 -11.2 -17.2 -27.8 244 450 A L > - 0 0 108 -2,-0.2 3,-1.9 1,-0.1 21,-0.3 -0.849 26.6 -88.3-112.8 150.6 -14.2 -15.4 -29.1 245 451 A V T 3 S+ 0 0 65 -2,-0.3 21,-0.2 1,-0.2 3,-0.1 -0.256 112.4 24.1 -54.8 138.9 -15.4 -11.9 -28.1 246 452 A N T 3 S+ 0 0 117 19,-3.2 -231,-0.4 1,-0.3 -1,-0.2 0.159 84.0 137.2 85.1 -10.2 -17.7 -11.8 -25.0 247 453 A M < - 0 0 15 -3,-1.9 18,-2.2 18,-0.1 -1,-0.3 -0.439 49.8-130.6 -62.7 139.9 -16.4 -15.1 -23.6 248 454 A K E +aB 16 264A 21 -233,-2.2 -231,-2.9 16,-0.2 50,-0.4 -0.675 39.0 142.5 -96.6 149.9 -15.9 -14.8 -19.8 249 455 A L E - B 0 263A 0 14,-2.5 14,-2.8 -2,-0.3 2,-0.4 -0.852 46.3 -91.2-159.6-168.9 -12.8 -15.8 -17.8 250 456 A E E +CB 296 262A 1 46,-2.7 46,-2.6 -2,-0.2 2,-0.3 -0.951 39.1 178.5-121.2 137.7 -10.6 -14.8 -14.9 251 457 A A E -CB 295 261A 0 10,-2.0 10,-2.6 -2,-0.4 44,-0.2 -1.000 32.3-110.3-144.0 142.5 -7.5 -12.5 -15.1 252 458 A V E - B 0 260A 8 42,-2.4 2,-0.3 -2,-0.3 8,-0.3 -0.485 39.7-115.5 -64.2 139.9 -5.0 -11.0 -12.8 253 459 A D - 0 0 10 6,-2.8 6,-0.2 3,-0.4 -1,-0.1 -0.626 17.9-152.1 -77.8 131.1 -5.4 -7.2 -12.5 254 460 A R S S+ 0 0 144 -2,-0.3 -1,-0.1 30,-0.2 -2,-0.0 0.843 93.5 50.9 -76.7 -30.7 -2.3 -5.4 -13.9 255 461 A R S S+ 0 0 171 1,-0.3 -1,-0.2 29,-0.1 3,-0.0 0.823 129.3 18.4 -74.3 -34.7 -2.6 -2.4 -11.6 256 462 A N S > S- 0 0 78 3,-0.1 3,-2.6 1,-0.1 -3,-0.4 -0.732 73.2-173.3-134.8 85.7 -2.9 -4.5 -8.4 257 463 A P T 3 S+ 0 0 53 0, 0.0 -3,-0.1 0, 0.0 -2,-0.1 0.537 77.1 74.8 -65.9 -5.8 -1.6 -7.9 -9.3 258 464 A A T 3 S+ 0 0 27 -6,-0.1 2,-0.3 -3,-0.0 -4,-0.1 0.785 91.7 75.5 -65.2 -26.4 -2.6 -9.3 -5.9 259 465 A L < - 0 0 41 -3,-2.6 -6,-2.8 -6,-0.2 2,-0.4 -0.622 61.1-166.1 -96.8 143.2 -6.2 -9.2 -7.3 260 466 A I E -B 252 0A 0 47,-0.4 49,-3.1 -2,-0.3 2,-0.3 -0.992 19.7-167.4-123.6 135.9 -7.9 -11.5 -9.9 261 467 A R E -Bd 251 309A 29 -10,-2.6 -10,-2.0 -2,-0.4 2,-0.2 -0.864 31.4 -92.5-125.6 154.3 -11.2 -10.3 -11.4 262 468 A V E -B 250 0A 1 47,-2.0 16,-1.2 -2,-0.3 2,-0.3 -0.462 56.9-173.0 -58.8 130.4 -14.1 -11.5 -13.5 263 469 A A E -BE 249 277A 0 -14,-2.8 -14,-2.5 14,-0.2 2,-0.3 -0.904 22.3-154.4-137.8 157.4 -13.1 -10.7 -17.1 264 470 A S E -BE 248 276A 11 12,-2.6 12,-2.4 -2,-0.3 2,-0.8 -0.949 31.4-110.3-128.9 149.8 -14.5 -10.7 -20.7 265 471 A V E + E 0 275A 1 -18,-2.2 -19,-3.2 -2,-0.3 10,-0.2 -0.755 36.5 177.1 -79.9 114.4 -12.8 -11.0 -24.0 266 472 A E E - 0 0 73 8,-3.4 2,-0.3 -2,-0.8 -1,-0.2 0.775 63.2 -10.7 -90.4 -33.4 -13.2 -7.5 -25.5 267 473 A D E - E 0 274A 71 7,-1.1 7,-2.8 -23,-0.1 2,-0.3 -0.960 65.2-141.8-159.9 167.2 -11.3 -8.1 -28.7 268 474 A V E - E 0 273A 53 -2,-0.3 2,-0.2 5,-0.2 5,-0.2 -0.982 12.6-176.8-141.7 149.3 -9.0 -10.6 -30.4 269 475 A E - 0 0 87 3,-2.8 -28,-0.2 -2,-0.3 5,-0.0 -0.729 54.7 -87.9-122.3 178.5 -5.9 -11.0 -32.6 270 476 A D S S+ 0 0 110 -2,-0.2 -29,-1.9 1,-0.2 3,-0.0 0.878 124.6 11.4 -56.8 -37.3 -4.5 -14.4 -33.8 271 477 A H S S+ 0 0 51 -31,-0.2 19,-2.5 1,-0.0 20,-0.4 0.330 123.2 58.1-126.4 5.2 -2.3 -14.8 -30.7 272 478 A R E - F 0 289A 70 17,-0.3 -3,-2.8 18,-0.1 2,-0.3 -0.966 56.8-155.4-137.8 152.6 -3.5 -12.1 -28.2 273 479 A I E -EF 268 288A 0 15,-2.6 15,-2.5 -2,-0.3 2,-0.6 -0.923 17.8-130.1-125.4 151.2 -6.8 -11.2 -26.5 274 480 A K E -EF 267 287A 60 -7,-2.8 -8,-3.4 -2,-0.3 -7,-1.1 -0.928 25.8-146.9-103.3 126.5 -7.9 -7.9 -25.1 275 481 A I E -EF 265 286A 0 11,-3.0 11,-1.8 -2,-0.6 2,-0.4 -0.771 14.0-171.9 -96.5 135.5 -9.3 -8.2 -21.6 276 482 A H E -E 264 0A 17 -12,-2.4 -12,-2.6 -2,-0.4 2,-0.6 -0.993 22.4-132.9-120.4 130.8 -12.1 -6.1 -20.1 277 483 A F E > -E 263 0A 6 -2,-0.4 3,-2.2 4,-0.3 -14,-0.2 -0.778 35.0-109.1 -83.3 119.8 -12.9 -6.3 -16.4 278 484 A D T 3 S+ 0 0 7 -16,-1.2 34,-1.6 -2,-0.6 -16,-0.1 -0.194 99.4 12.1 -51.6 129.6 -16.6 -6.7 -16.0 279 485 A G T 3 S+ 0 0 27 1,-0.3 41,-2.1 32,-0.3 -1,-0.3 0.145 105.8 110.7 92.8 -19.2 -18.3 -3.5 -14.6 280 486 A W B < S-S 319 0D 32 -3,-2.2 -1,-0.3 39,-0.3 39,-0.3 -0.447 75.6 -93.9 -87.9 159.5 -15.2 -1.3 -15.0 281 487 A S > - 0 0 41 37,-3.1 3,-0.7 39,-0.1 -4,-0.3 -0.153 36.0-115.7 -50.8 157.4 -14.4 1.6 -17.4 282 488 A H G > S+ 0 0 103 1,-0.2 3,-1.7 37,-0.1 -1,-0.1 0.615 100.6 90.2 -78.5 -9.3 -12.7 0.7 -20.7 283 489 A G G 3 S+ 0 0 69 1,-0.3 -1,-0.2 35,-0.1 -2,-0.0 0.719 88.2 47.4 -54.7 -24.9 -9.7 2.7 -19.5 284 490 A Y G < S+ 0 0 70 -3,-0.7 -1,-0.3 -7,-0.1 -30,-0.2 0.431 80.8 123.0 -98.9 -6.0 -8.2 -0.4 -17.9 285 491 A D < - 0 0 25 -3,-1.7 2,-0.3 -4,-0.1 -9,-0.2 -0.260 41.5-175.6 -57.4 144.8 -8.7 -2.8 -20.8 286 492 A F E -F 275 0A 21 -11,-1.8 -11,-3.0 2,-0.0 2,-0.3 -0.999 27.5-119.8-148.3 148.3 -5.4 -4.4 -21.9 287 493 A W E +F 274 0A 64 -2,-0.3 2,-0.3 -13,-0.3 -13,-0.2 -0.673 35.6 175.4 -84.2 142.9 -4.0 -6.7 -24.6 288 494 A I E -F 273 0A 6 -15,-2.5 -15,-2.6 -2,-0.3 2,-0.1 -0.992 37.2 -98.6-147.3 143.9 -2.3 -10.0 -23.3 289 495 A D E > -F 272 0A 21 -2,-0.3 3,-2.0 -17,-0.2 -17,-0.3 -0.430 32.9-126.2 -59.7 141.2 -0.8 -13.0 -25.0 290 496 A A T 3 S+ 0 0 13 -19,-2.5 -267,-0.3 1,-0.3 -1,-0.1 0.747 111.2 49.7 -64.8 -23.4 -3.3 -15.9 -25.1 291 497 A D T 3 S+ 0 0 56 -20,-0.4 -1,-0.3 -269,-0.1 -2,-0.1 0.224 80.2 136.6 -95.9 14.7 -0.7 -18.2 -23.4 292 498 A H X - 0 0 54 -3,-2.0 3,-1.3 1,-0.1 -4,-0.0 -0.381 59.4-131.6 -64.7 137.9 0.0 -15.7 -20.6 293 499 A P T 3 S+ 0 0 70 0, 0.0 -1,-0.1 0, 0.0 -3,-0.0 0.599 98.6 66.5 -65.5 -9.9 0.2 -17.3 -17.2 294 500 A D T 3 S+ 0 0 33 -42,-0.1 -42,-2.4 2,-0.0 2,-0.4 0.138 83.4 79.6-107.2 21.5 -2.1 -14.8 -15.6 295 501 A I E < +C 251 0A 0 -3,-1.3 -44,-0.2 -44,-0.2 -46,-0.0 -0.956 58.7 172.6-119.1 147.4 -5.3 -15.6 -17.5 296 502 A H E -C 250 0A 1 -46,-2.6 -46,-2.7 -2,-0.4 -269,-0.1 -0.971 33.6 -93.1-148.0 158.6 -7.4 -18.6 -16.4 297 503 A P > - 0 0 6 0, 0.0 3,-2.1 0, 0.0 4,-0.2 -0.388 58.3 -81.2 -72.4 155.6 -10.8 -20.3 -17.0 298 504 A A T 3 S+ 0 0 22 -50,-0.4 -279,-0.1 -281,-0.3 -48,-0.0 -0.278 119.7 34.3 -49.1 134.8 -13.8 -19.5 -14.9 299 505 A G T 3> S+ 0 0 13 -3,-0.1 4,-2.8 -50,-0.0 -1,-0.2 0.146 82.1 111.6 99.0 -15.4 -13.6 -21.4 -11.6 300 506 A W H <> S+ 0 0 4 -3,-2.1 4,-1.8 1,-0.2 6,-0.2 0.930 79.4 46.3 -56.7 -48.1 -9.8 -21.3 -11.3 301 507 A C H >>S+ 0 0 0 -4,-0.2 5,-2.2 1,-0.2 4,-1.5 0.952 115.0 47.5 -59.5 -48.9 -9.9 -18.9 -8.2 302 508 A S H 45S+ 0 0 104 1,-0.2 3,-0.3 2,-0.2 -2,-0.2 0.920 114.6 45.6 -58.9 -45.2 -12.6 -21.0 -6.5 303 509 A K H <5S+ 0 0 128 -4,-2.8 -1,-0.2 1,-0.2 -2,-0.2 0.732 119.1 40.7 -72.4 -25.7 -10.8 -24.3 -7.2 304 510 A T H <5S- 0 0 19 -4,-1.8 -1,-0.2 -3,-0.3 -2,-0.2 0.524 112.7-110.9-101.0 -10.6 -7.4 -23.1 -6.1 305 511 A G T <5 + 0 0 56 -4,-1.5 -243,-0.5 1,-0.3 -3,-0.2 0.759 69.9 135.9 86.0 27.1 -8.5 -21.0 -3.0 306 512 A H < - 0 0 9 -5,-2.2 -1,-0.3 -6,-0.2 -2,-0.1 -0.861 59.2-109.8-102.1 138.3 -7.8 -17.5 -4.4 307 513 A P - 0 0 76 0, 0.0 2,-0.4 0, 0.0 -47,-0.4 -0.418 28.1-147.6 -64.0 147.0 -10.3 -14.7 -3.9 308 514 A L - 0 0 41 -49,-0.1 -47,-0.2 -2,-0.1 -49,-0.0 -0.973 9.3-134.7-116.2 126.0 -12.1 -13.6 -7.0 309 515 A Q B -d 261 0A 58 -49,-3.1 -47,-2.0 -2,-0.4 3,-0.1 -0.697 22.9-138.8 -79.3 124.6 -13.2 -9.9 -7.4 310 516 A P - 0 0 64 0, 0.0 3,-0.1 0, 0.0 -1,-0.0 -0.306 42.2 -65.7 -74.4 170.0 -16.8 -9.7 -8.6 311 517 A P - 0 0 32 0, 0.0 -32,-0.3 0, 0.0 2,-0.1 -0.177 63.7 -94.9 -55.8 146.1 -17.7 -7.1 -11.3 312 518 A L - 0 0 30 -34,-1.6 8,-0.2 1,-0.1 6,-0.0 -0.402 50.3-100.6 -61.2 138.2 -17.5 -3.5 -10.1 313 519 A G > - 0 0 26 -3,-0.1 3,-1.2 -2,-0.1 -1,-0.1 -0.128 38.4 -96.9 -61.3 159.1 -20.9 -2.2 -8.8 314 520 A P T 3 S+ 0 0 82 0, 0.0 -1,-0.1 0, 0.0 -2,-0.1 0.799 109.6 23.6 -56.1 -48.3 -23.1 0.0 -11.0 315 521 A R T 3 S+ 0 0 207 6,-0.0 3,-0.1 3,-0.0 -2,-0.1 0.191 90.3 129.1-112.7 32.4 -22.5 3.7 -10.1 316 522 A E S X S- 0 0 106 -3,-1.2 3,-1.4 1,-0.2 -4,-0.0 -0.247 71.1 -87.1 -75.3 159.7 -19.0 3.4 -8.7 317 523 A P T 3 S+ 0 0 102 0, 0.0 -1,-0.2 0, 0.0 3,-0.1 -0.394 118.5 22.6 -55.1 147.8 -16.0 5.6 -9.7 318 524 A S T 3 S+ 0 0 52 1,-0.2 -37,-3.1 -38,-0.1 2,-0.1 0.606 97.6 138.6 67.1 14.2 -14.2 3.9 -12.7 319 525 A S B < -S 280 0D 32 -3,-1.4 -39,-0.3 -39,-0.3 -1,-0.2 -0.481 53.7-110.3 -92.9 160.3 -17.4 2.0 -13.6 320 526 A A - 0 0 35 -41,-2.1 -39,-0.1 -39,-0.2 -1,-0.1 -0.366 46.5 -79.6 -83.5 169.1 -18.9 1.5 -17.1 321 527 A S 0 0 112 1,-0.1 -1,-0.1 -41,-0.1 -42,-0.1 -0.310 360.0 360.0 -66.8 147.3 -22.1 3.1 -18.4 322 528 A P 0 0 164 0, 0.0 -1,-0.1 0, 0.0 -7,-0.0 0.535 360.0 360.0 -84.1 360.0 -25.4 1.6 -17.3