==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=12-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 14-JAN-04 1S3Y . COMPND 2 MOLECULE: DIHYDROFOLATE REDUCTASE; . SOURCE 2 ORGANISM_SCIENTIFIC: PNEUMOCYSTIS CARINII; . AUTHOR V.CODY,J.R.LUFT,W.PANGBORN,A.GANGJEE,S.F.QUEENER . 206 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 11992.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 125 60.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 33 16.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 19 9.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 20 9.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 16 7.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 36 17.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 1 1 1 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 2 0 1 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 2 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A M 0 0 196 0, 0.0 3,-0.1 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 54.8 -9.5 20.4 25.8 2 2 A N + 0 0 53 1,-0.1 3,-0.1 2,-0.0 104,-0.1 0.412 360.0 48.6-120.4 -7.0 -5.9 19.2 25.8 3 3 A Q + 0 0 110 1,-0.1 -1,-0.1 100,-0.0 100,-0.0 -0.343 62.1 126.1-131.6 51.9 -6.6 15.5 25.1 4 4 A Q S S+ 0 0 83 -3,-0.1 2,-0.3 1,-0.0 -1,-0.1 0.344 73.0 52.2 -90.0 6.0 -8.9 15.6 22.1 5 5 A K S S- 0 0 65 -3,-0.1 2,-0.2 114,-0.0 114,-0.1 -1.000 76.5-132.0-143.6 143.4 -6.5 13.3 20.2 6 6 A S - 0 0 46 -2,-0.3 114,-0.6 1,-0.0 2,-0.2 -0.579 26.5-122.9 -91.6 156.5 -4.8 10.0 20.9 7 7 A L E -ab 120 138A 0 130,-0.6 132,-1.4 -2,-0.2 133,-0.7 -0.663 14.5-150.8-100.1 156.4 -1.1 9.3 20.4 8 8 A T E -ab 121 140A 4 112,-1.7 114,-3.6 -2,-0.2 2,-0.5 -0.993 4.6-149.9-128.6 132.8 0.6 6.7 18.2 9 9 A L E -ab 122 141A 0 131,-2.5 133,-3.7 -2,-0.4 2,-0.4 -0.850 12.8-171.5 -99.4 130.5 4.0 5.2 18.8 10 10 A I E + b 0 142A 6 112,-2.8 2,-0.3 -2,-0.5 133,-0.2 -0.990 19.8 150.1-124.1 133.3 6.0 4.1 15.8 11 11 A V E - b 0 143A 11 131,-2.7 133,-1.7 -2,-0.4 2,-0.4 -0.991 39.2-138.3-160.0 158.6 9.2 2.2 16.3 12 12 A A E + b 0 144A 21 -2,-0.3 2,-0.3 131,-0.2 133,-0.2 -0.994 38.5 155.8-123.3 126.5 11.5 -0.5 14.8 13 13 A L E - b 0 145A 1 131,-2.9 133,-3.0 -2,-0.4 6,-0.2 -0.971 37.7-109.3-149.6 163.3 12.9 -3.1 17.2 14 14 A T E > - b 0 146A 5 4,-1.8 3,-3.1 -2,-0.3 133,-0.2 -0.454 43.9 -97.5 -90.0 168.0 14.4 -6.6 17.4 15 15 A T T 3 S+ 0 0 59 131,-1.2 132,-0.1 1,-0.3 -1,-0.1 0.731 129.7 55.2 -54.5 -22.0 12.7 -9.6 19.0 16 16 A S T 3 S- 0 0 52 132,-0.1 -1,-0.3 2,-0.1 3,-0.1 0.262 121.3-111.8 -95.1 10.7 14.8 -8.8 22.0 17 17 A Y < + 0 0 8 -3,-3.1 139,-2.6 1,-0.2 2,-0.2 0.664 62.8 156.9 68.8 18.1 13.3 -5.2 22.1 18 18 A G E +I 155 0B 0 137,-0.2 -4,-1.8 1,-0.1 137,-0.3 -0.555 11.9 164.9 -73.5 137.6 16.6 -3.7 21.1 19 19 A I E + 0 0 30 135,-3.4 2,-0.3 1,-0.3 136,-0.2 0.394 57.8 29.9-131.0 -3.0 16.2 -0.3 19.5 20 20 A G E -I 154 0B 14 134,-1.5 133,-2.9 5,-0.1 134,-2.0 -0.995 50.3-155.6-160.9 152.2 19.7 1.2 19.6 21 21 A R S S- 0 0 93 131,-0.3 4,-0.4 -2,-0.3 131,-0.1 -0.944 70.8 -61.1-134.6 109.2 23.4 0.5 19.6 22 22 A S S S- 0 0 68 -2,-0.4 2,-2.8 1,-0.3 -2,-0.0 0.683 105.0 -56.9 14.6 67.8 25.8 3.0 21.1 23 23 A N S S+ 0 0 137 1,-0.1 -1,-0.3 0, 0.0 -2,-0.3 -0.385 121.6 106.6 73.1 -64.6 24.6 5.6 18.6 24 24 A S S S- 0 0 83 -2,-2.8 -2,-0.1 1,-0.1 -1,-0.1 0.493 74.3-132.6 -1.6 -87.0 25.5 3.3 15.7 25 25 A L - 0 0 95 -4,-0.4 2,-0.8 1,-0.0 -1,-0.1 0.791 11.4-136.5 107.9 76.9 22.2 2.0 14.3 26 26 A P S S+ 0 0 22 0, 0.0 2,-0.3 0, 0.0 125,-0.1 0.278 72.3 47.1 -36.7 -4.7 22.5 -1.9 13.9 27 27 A W - 0 0 34 -2,-0.8 2,-0.7 123,-0.0 166,-0.1 -0.998 62.1-136.2-154.9 153.6 20.9 -2.2 10.4 28 28 A K + 0 0 154 -2,-0.3 2,-0.4 165,-0.3 167,-0.2 -0.863 36.3 156.8-107.5 98.0 20.5 -0.9 6.8 29 29 A L > + 0 0 10 -2,-0.7 4,-1.9 1,-0.1 5,-0.2 -0.702 10.9 165.6-126.5 81.2 16.8 -0.7 5.9 30 30 A K H > S+ 0 0 140 -2,-0.4 4,-1.2 1,-0.2 -1,-0.1 0.844 84.9 50.5 -62.3 -33.6 16.1 1.7 3.1 31 31 A K H > S+ 0 0 118 2,-0.2 4,-2.0 1,-0.2 -1,-0.2 0.838 104.6 56.3 -72.6 -35.8 12.6 0.2 2.7 32 32 A E H > S+ 0 0 17 2,-0.2 4,-3.0 1,-0.2 3,-0.2 0.959 107.0 49.2 -61.3 -49.8 11.8 0.5 6.4 33 33 A I H X S+ 0 0 93 -4,-1.9 4,-3.1 1,-0.3 5,-0.2 0.866 107.9 56.1 -55.6 -38.9 12.5 4.3 6.3 34 34 A S H X S+ 0 0 51 -4,-1.2 4,-2.2 2,-0.2 -1,-0.3 0.916 109.1 45.0 -61.1 -44.1 10.2 4.4 3.3 35 35 A Y H X S+ 0 0 11 -4,-2.0 4,-3.2 -3,-0.2 5,-0.2 0.944 112.2 53.6 -63.4 -47.6 7.4 2.8 5.3 36 36 A F H X S+ 0 0 41 -4,-3.0 4,-2.4 1,-0.2 -2,-0.2 0.917 110.8 44.7 -51.9 -52.4 8.2 5.2 8.2 37 37 A K H X S+ 0 0 110 -4,-3.1 4,-1.0 1,-0.2 -1,-0.2 0.905 113.9 50.6 -61.3 -43.2 7.9 8.2 6.0 38 38 A R H X S+ 0 0 125 -4,-2.2 4,-1.8 -5,-0.2 3,-0.3 0.922 112.7 45.2 -62.9 -45.8 4.7 6.9 4.3 39 39 A V H < S+ 0 0 1 -4,-3.2 -2,-0.2 1,-0.2 -1,-0.2 0.945 115.5 44.5 -65.2 -48.5 3.0 6.2 7.6 40 40 A T H < S+ 0 0 0 -4,-2.4 -1,-0.2 -5,-0.2 -2,-0.2 0.601 118.2 45.6 -74.6 -7.9 3.9 9.4 9.4 41 41 A S H < S+ 0 0 44 -4,-1.0 -1,-0.2 -3,-0.3 -2,-0.2 0.708 83.1 113.5-103.7 -26.7 3.0 11.5 6.3 42 42 A F < + 0 0 51 -4,-1.8 140,-0.1 -5,-0.2 -3,-0.0 -0.155 35.8 164.3 -53.5 134.6 -0.3 9.9 5.3 43 43 A V - 0 0 16 138,-0.1 5,-0.1 75,-0.1 -2,-0.0 -0.979 48.4 -84.7-151.8 138.9 -3.4 12.1 5.6 44 44 A P - 0 0 47 0, 0.0 3,-0.3 0, 0.0 7,-0.1 -0.201 36.9-132.5 -48.1 123.8 -6.9 11.8 4.2 45 45 A T S > S+ 0 0 124 1,-0.2 3,-2.0 2,-0.2 4,-0.3 0.889 103.5 57.7 -46.0 -49.1 -6.9 13.2 0.7 46 46 A F G > S+ 0 0 184 1,-0.3 3,-0.5 2,-0.1 -1,-0.2 0.935 116.7 32.6 -48.7 -55.7 -10.1 15.2 1.3 47 47 A D G 3> S+ 0 0 50 -3,-0.3 4,-0.7 1,-0.2 -1,-0.3 -0.170 89.8 104.5 -96.6 39.8 -8.5 17.1 4.3 48 48 A S G <4 + 0 0 57 -3,-2.0 -1,-0.2 1,-0.2 -2,-0.1 0.550 59.3 80.1 -93.7 -10.2 -5.0 17.1 2.8 49 49 A F T <4 S- 0 0 196 -3,-0.5 -1,-0.2 -4,-0.3 -2,-0.1 0.796 120.8 -3.8 -66.7 -28.8 -5.2 20.8 1.9 50 50 A E T 4 S+ 0 0 84 -3,-0.2 -2,-0.1 65,-0.0 -1,-0.1 0.614 105.2 101.3-131.1 -41.8 -4.4 21.9 5.4 51 51 A S < + 0 0 22 -4,-0.7 2,-0.3 64,-0.2 66,-0.2 -0.166 44.2 176.6 -54.9 139.8 -4.2 18.9 7.8 52 52 A M E -c 117 0A 56 64,-2.2 66,-2.2 -3,-0.0 67,-0.2 -0.989 24.3-123.5-144.4 149.9 -0.7 17.7 8.7 53 53 A N E - d 0 75A 1 21,-0.5 23,-2.4 -2,-0.3 2,-0.4 -0.464 23.5-132.3 -89.4 167.9 0.6 15.0 11.1 54 54 A V E -cd 120 76A 0 65,-3.0 67,-2.9 21,-0.2 2,-0.5 -0.934 9.1-157.8-124.2 143.6 3.0 15.6 13.9 55 55 A V E -cd 121 77A 0 21,-2.6 23,-1.9 -2,-0.4 2,-0.4 -0.978 7.5-166.5-123.0 121.5 6.2 13.8 14.9 56 56 A L E +cd 122 78A 0 65,-2.9 67,-2.4 -2,-0.5 68,-1.0 -0.872 18.4 162.5-105.4 137.7 7.4 14.1 18.5 57 57 A M E -cd 124 79A 0 21,-1.5 23,-2.4 -2,-0.4 68,-0.2 -0.989 36.3-106.3-152.8 157.1 10.9 12.9 19.3 58 58 A G E > - d 0 80A 14 66,-1.7 4,-1.9 -2,-0.3 3,-0.4 -0.411 39.2-104.9 -81.8 162.5 13.6 13.2 21.9 59 59 A R H > S+ 0 0 107 21,-1.0 4,-1.7 1,-0.2 5,-0.2 0.904 118.4 55.2 -51.8 -53.6 16.7 15.3 21.5 60 60 A K H > S+ 0 0 148 1,-0.2 4,-2.3 2,-0.2 -1,-0.2 0.869 108.0 50.4 -49.7 -42.0 19.1 12.4 20.9 61 61 A T H > S+ 0 0 30 -3,-0.4 4,-0.8 1,-0.2 -1,-0.2 0.936 105.5 55.7 -63.7 -46.1 16.8 11.3 18.0 62 62 A W H < S+ 0 0 45 -4,-1.9 3,-0.3 1,-0.2 -1,-0.2 0.825 111.9 43.7 -55.8 -33.5 16.9 14.7 16.5 63 63 A E H < S+ 0 0 105 -4,-1.7 -1,-0.2 1,-0.2 -2,-0.2 0.859 102.6 65.9 -79.5 -37.0 20.7 14.6 16.4 64 64 A S H < S+ 0 0 83 -4,-2.3 -1,-0.2 -5,-0.2 -2,-0.2 0.649 89.1 84.4 -59.4 -15.2 20.7 11.0 15.1 65 65 A I S < S- 0 0 29 -4,-0.8 5,-0.0 -3,-0.3 -4,-0.0 -0.806 88.0-116.4 -96.6 127.1 19.1 12.3 11.9 66 66 A P > - 0 0 65 0, 0.0 3,-0.8 0, 0.0 4,-0.3 -0.224 26.2-112.2 -57.7 145.5 21.4 13.8 9.2 67 67 A L G > S+ 0 0 142 1,-0.2 3,-1.3 2,-0.2 -2,-0.0 0.781 112.4 76.3 -48.5 -27.3 21.0 17.5 8.4 68 68 A Q G 3 S+ 0 0 144 1,-0.3 -1,-0.2 0, 0.0 -3,-0.0 0.944 103.5 27.8 -48.4 -64.9 19.8 16.1 5.1 69 69 A F G < S+ 0 0 119 -3,-0.8 -1,-0.3 3,-0.1 -2,-0.2 0.067 94.6 147.3 -91.4 23.9 16.3 15.0 6.3 70 70 A R < + 0 0 62 -3,-1.3 2,-0.1 -4,-0.3 -8,-0.0 -0.939 62.5 24.1-114.4 123.6 16.0 17.6 9.1 71 71 A P S S- 0 0 49 0, 0.0 2,-0.6 0, 0.0 -1,-0.1 0.574 98.6-114.8 -86.0 164.5 13.4 18.6 9.7 72 72 A L > - 0 0 15 -2,-0.1 3,-1.1 1,-0.1 -2,-0.1 -0.445 40.0-133.0 -61.3 109.6 11.1 15.9 8.4 73 73 A K T 3 S+ 0 0 169 -2,-0.6 3,-0.1 1,-0.2 -1,-0.1 -0.251 82.8 26.0 -66.8 150.7 9.2 17.7 5.6 74 74 A G T 3 S+ 0 0 56 1,-0.1 -21,-0.5 -22,-0.0 2,-0.3 0.470 111.7 83.9 76.5 1.0 5.5 17.6 5.3 75 75 A R E < S-d 53 0A 17 -3,-1.1 2,-0.5 -23,-0.1 -21,-0.2 -0.998 85.3-111.4-139.5 140.9 5.2 17.0 9.0 76 76 A I E -d 54 0A 10 -23,-2.4 -21,-2.6 -2,-0.3 2,-0.4 -0.560 36.9-150.5 -70.4 119.1 5.2 19.2 12.1 77 77 A N E +d 55 0A 5 -2,-0.5 16,-2.6 14,-0.3 2,-0.4 -0.805 20.5 172.8 -98.8 132.0 8.4 18.6 14.0 78 78 A V E -de 56 93A 1 -23,-1.9 -21,-1.5 -2,-0.4 2,-0.4 -0.968 14.7-157.8-139.7 119.3 8.6 19.0 17.7 79 79 A V E -de 57 94A 14 14,-2.3 16,-2.2 -2,-0.4 2,-0.4 -0.831 12.6-140.4 -98.8 134.3 11.6 18.1 19.8 80 80 A I E +de 58 95A 20 -23,-2.4 -21,-1.0 -2,-0.4 2,-0.3 -0.808 39.3 139.8 -95.5 131.9 11.2 17.4 23.5 81 81 A T - 0 0 14 14,-3.8 3,-0.2 -2,-0.4 16,-0.1 -0.910 39.7-159.2-172.3 141.4 13.9 18.7 25.8 82 82 A R S S+ 0 0 201 -2,-0.3 2,-1.9 1,-0.2 -1,-0.1 0.928 88.8 57.5 -87.1 -64.4 14.4 20.4 29.2 83 83 A N S S+ 0 0 112 13,-0.1 2,-0.8 1,-0.1 -1,-0.2 -0.517 71.2 169.2 -73.3 86.7 17.9 21.9 28.9 84 84 A E + 0 0 109 -2,-1.9 -1,-0.1 -3,-0.2 -3,-0.0 -0.851 11.5 141.5-106.9 99.7 17.2 24.1 25.8 85 85 A S S S+ 0 0 86 -2,-0.8 2,-2.1 1,-0.1 -1,-0.1 0.653 72.1 8.6 -98.6-105.6 20.0 26.5 25.2 86 86 A L S S+ 0 0 149 0, 0.0 2,-0.4 0, 0.0 -1,-0.1 -0.299 80.8 173.2 -78.8 54.6 21.2 27.4 21.7 87 87 A D - 0 0 74 -2,-2.1 -3,-0.0 1,-0.1 7,-0.0 -0.525 9.7-169.3 -69.2 120.1 18.3 25.5 20.1 88 88 A L + 0 0 173 -2,-0.4 -1,-0.1 2,-0.0 2,-0.1 0.586 29.1 119.4 -80.4-128.3 18.4 26.1 16.3 89 89 A G - 0 0 40 1,-0.1 4,-0.0 2,-0.1 0, 0.0 -0.302 43.6-146.8 90.7-178.6 15.6 25.1 14.0 90 90 A N S S+ 0 0 172 -2,-0.1 -1,-0.1 3,-0.0 3,-0.0 0.311 93.8 11.1-159.9 -30.9 13.4 27.3 11.7 91 91 A G S S+ 0 0 55 2,-0.1 -14,-0.3 -14,-0.0 2,-0.2 0.243 104.3 105.1-139.0 5.1 10.0 25.7 11.7 92 92 A I - 0 0 35 -16,-0.1 -14,-0.2 -4,-0.0 2,-0.2 -0.593 59.8-136.5 -91.3 153.4 10.4 23.1 14.5 93 93 A H E -e 78 0A 39 -16,-2.6 -14,-2.3 -2,-0.2 2,-0.4 -0.629 8.0-142.2-106.3 165.8 9.0 23.5 18.0 94 94 A S E +e 79 0A 55 -2,-0.2 2,-0.3 -16,-0.2 -14,-0.2 -0.992 20.1 171.3-134.1 130.6 10.5 22.9 21.4 95 95 A A E -e 80 0A 8 -16,-2.2 -14,-3.8 -2,-0.4 3,-0.1 -0.986 32.2-144.0-138.5 148.3 8.9 21.4 24.5 96 96 A K S S+ 0 0 130 -2,-0.3 2,-0.3 -16,-0.2 -14,-0.1 0.592 84.7 8.7 -87.4 -8.8 10.1 20.2 27.9 97 97 A S S > S- 0 0 38 -16,-0.1 4,-2.2 1,-0.1 5,-0.2 -0.983 77.7-100.6-161.6 166.7 7.7 17.3 28.2 98 98 A L H > S+ 0 0 12 -2,-0.3 4,-1.6 1,-0.2 -1,-0.1 0.892 122.7 43.4 -60.6 -43.8 5.1 15.2 26.3 99 99 A D H > S+ 0 0 82 1,-0.2 4,-2.0 2,-0.2 -1,-0.2 0.884 111.3 55.4 -72.7 -33.7 2.2 16.9 27.8 100 100 A H H > S+ 0 0 73 1,-0.2 4,-1.6 2,-0.2 -2,-0.2 0.875 107.1 50.1 -64.0 -37.7 3.8 20.4 27.4 101 101 A A H X S+ 0 0 0 -4,-2.2 4,-2.4 2,-0.2 -1,-0.2 0.901 108.2 53.4 -66.8 -42.6 4.2 19.7 23.6 102 102 A L H X S+ 0 0 2 -4,-1.6 4,-2.0 1,-0.2 5,-0.2 0.949 108.3 48.1 -58.1 -50.9 0.6 18.7 23.2 103 103 A E H X S+ 0 0 86 -4,-2.0 4,-1.1 1,-0.2 -1,-0.2 0.861 111.6 51.0 -59.5 -37.5 -0.7 21.9 24.9 104 104 A L H X S+ 0 0 36 -4,-1.6 4,-2.9 1,-0.2 5,-0.3 0.901 108.6 52.1 -66.4 -39.6 1.5 24.0 22.7 105 105 A L H X S+ 0 0 1 -4,-2.4 4,-1.4 1,-0.2 -2,-0.2 0.838 109.7 48.8 -65.5 -34.6 0.3 22.2 19.5 106 106 A Y H < S+ 0 0 36 -4,-2.0 -1,-0.2 2,-0.2 -2,-0.2 0.725 117.0 41.5 -79.0 -20.2 -3.3 22.8 20.4 107 107 A R H >< S+ 0 0 193 -4,-1.1 3,-0.6 -3,-0.3 -2,-0.2 0.806 118.8 43.0 -93.6 -35.3 -2.7 26.5 21.1 108 108 A T H 3< S+ 0 0 56 -4,-2.9 -3,-0.2 1,-0.2 -2,-0.2 0.770 124.3 36.9 -80.3 -26.3 -0.4 27.1 18.1 109 109 A Y T 3< S+ 0 0 43 -4,-1.4 8,-0.5 -5,-0.3 -1,-0.2 -0.340 86.6 131.2-122.5 50.0 -2.6 25.1 15.8 110 110 A G S X S- 0 0 25 -3,-0.6 3,-1.4 6,-0.1 5,-0.2 0.144 82.0 -69.1 -82.1-156.2 -6.1 25.9 16.9 111 111 A S T 3 S+ 0 0 106 1,-0.3 -1,-0.1 3,-0.1 5,-0.1 0.627 131.0 66.7 -73.1 -12.2 -9.0 26.9 14.7 112 112 A E T 3 S+ 0 0 185 3,-0.1 2,-0.3 2,-0.0 -1,-0.3 0.365 89.5 82.9 -88.6 3.8 -7.2 30.2 14.2 113 113 A S S < S- 0 0 28 -3,-1.4 -4,-0.1 1,-0.1 -5,-0.0 -0.816 74.1-140.1-109.6 150.7 -4.5 28.5 12.2 114 114 A S S S+ 0 0 109 -2,-0.3 2,-0.5 1,-0.1 -1,-0.1 0.425 91.6 69.7 -85.6 0.7 -4.5 27.5 8.6 115 115 A V - 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