==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=12-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER IMMUNE SYSTEM 05-FEB-04 1S9X . COMPND 2 MOLECULE: HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR A.I.WEBB,M.A.DUNSTONE,W.CHEN,M.I.AGUILAR,Q.CHEN,L.CHANG, . 383 3 3 3 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 18952.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 249 65.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 136 35.5 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 5 1.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 6 1.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 20 5.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 27 7.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 59 15.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 4 1.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 7 4 0 0 3 1 1 4 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 2 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A G 0 0 48 0, 0.0 106,-0.1 0, 0.0 102,-0.0 0.000 360.0 360.0 360.0-157.2 2.6 98.3 37.1 2 2 A S - 0 0 84 104,-0.1 2,-0.3 103,-0.0 102,-0.2 -0.276 360.0-172.7 -63.2 152.3 5.8 99.0 35.2 3 3 A H E -A 103 0A 19 100,-2.3 100,-3.1 101,-0.1 2,-0.3 -0.953 5.8-164.6-143.3 158.9 5.7 101.7 32.5 4 4 A S E -A 102 0A 7 -2,-0.3 25,-2.1 98,-0.2 2,-0.4 -0.977 14.5-147.9-146.5 159.4 8.0 103.0 29.9 5 5 A M E +AB 101 28A 1 96,-1.9 96,-1.8 -2,-0.3 2,-0.4 -1.000 26.8 179.3-126.5 128.1 8.6 105.9 27.6 6 6 A R E -AB 100 27A 70 21,-2.5 21,-3.1 -2,-0.4 2,-0.4 -0.996 18.2-158.3-139.3 139.8 10.2 105.2 24.2 7 7 A Y E -AB 99 26A 2 92,-2.6 92,-1.5 -2,-0.4 2,-0.4 -0.909 9.7-160.4-112.8 140.3 11.2 107.2 21.1 8 8 A F E -AB 98 25A 24 17,-3.0 17,-2.4 -2,-0.4 2,-0.4 -0.984 6.5-170.4-125.0 129.2 11.6 105.7 17.7 9 9 A F E -AB 97 24A 0 88,-3.5 88,-2.6 -2,-0.4 2,-0.4 -0.966 5.0-178.8-124.6 134.4 13.6 107.3 14.9 10 10 A T E -AB 96 23A 2 13,-2.0 13,-2.6 -2,-0.4 2,-0.4 -0.978 1.8-178.6-135.7 121.4 13.9 106.3 11.2 11 11 A S E -AB 95 22A 1 84,-3.0 84,-2.5 -2,-0.4 2,-0.4 -0.969 2.4-176.9-118.5 131.8 16.0 108.0 8.5 12 12 A V E -AB 94 21A 19 9,-1.9 9,-2.2 -2,-0.4 82,-0.2 -0.979 21.2-133.1-131.0 119.7 15.9 106.8 4.9 13 13 A S E - 0 0 17 80,-2.3 6,-0.1 -2,-0.4 62,-0.0 -0.364 17.1-173.2 -74.2 150.0 18.1 108.4 2.3 14 14 A R E >> - B 0 18A 66 4,-0.5 3,-2.5 78,-0.1 4,-2.1 -0.459 18.4-158.2-137.0 58.5 16.9 109.4 -1.2 15 15 A P T 34 S+ 0 0 56 0, 0.0 4,-0.1 0, 0.0 77,-0.0 -0.143 78.6 0.7 -44.5 116.3 20.1 110.5 -2.9 16 16 A G T 34 S+ 0 0 90 2,-0.2 3,-0.1 1,-0.1 74,-0.0 0.133 125.1 70.6 89.7 -22.1 19.2 112.8 -5.8 17 17 A R T <4 S- 0 0 229 -3,-2.5 2,-0.3 1,-0.3 -1,-0.1 0.786 107.9 -63.1 -97.5 -34.0 15.4 112.7 -5.1 18 18 A G E < S-B 14 0A 42 -4,-2.1 -4,-0.5 3,-0.0 -1,-0.3 -0.991 71.8 -33.7 173.2-170.2 15.1 114.7 -1.9 19 19 A E E S- 0 0 102 -2,-0.3 -7,-0.1 1,-0.1 3,-0.0 -0.402 78.1 -87.7 -69.2 149.1 16.0 115.0 1.8 20 20 A P E - 0 0 16 0, 0.0 2,-0.5 0, 0.0 -7,-0.3 -0.354 48.7-108.8 -58.7 139.6 16.2 111.8 3.6 21 21 A R E -B 12 0A 66 -9,-2.2 -9,-1.9 -3,-0.1 2,-0.5 -0.618 40.2-164.5 -71.2 121.0 12.7 110.9 4.9 22 22 A F E +B 11 0A 0 -2,-0.5 16,-2.0 -11,-0.2 2,-0.4 -0.941 12.6 175.1-113.1 126.1 12.8 111.3 8.6 23 23 A I E +BC 10 37A 11 -13,-2.6 -13,-2.0 -2,-0.5 2,-0.4 -0.963 1.9 178.5-135.7 120.0 10.1 109.9 10.9 24 24 A A E -BC 9 36A 1 12,-1.2 12,-2.1 -2,-0.4 2,-0.3 -0.909 3.7-175.3-117.7 145.2 10.2 110.0 14.7 25 25 A V E -BC 8 35A 2 -17,-2.4 -17,-3.0 -2,-0.4 2,-0.4 -0.997 11.1-148.9-141.5 146.0 7.5 108.6 17.0 26 26 A G E -BC 7 34A 0 8,-2.5 7,-2.0 -2,-0.3 8,-0.9 -0.932 14.1-173.0-119.0 140.9 7.0 108.7 20.8 27 27 A Y E -BC 6 32A 37 -21,-3.1 -21,-2.5 -2,-0.4 2,-0.5 -0.944 23.5-161.4-132.3 152.3 5.3 106.1 23.1 28 28 A V E > S-BC 5 31A 0 3,-2.4 3,-2.4 -2,-0.3 -23,-0.2 -0.970 83.1 -49.4-127.4 105.1 4.3 105.8 26.7 29 29 A D T 3 S- 0 0 31 -25,-2.1 -23,-0.1 -2,-0.5 -26,-0.1 -0.431 124.4 -22.3 60.0-124.0 3.8 102.0 27.0 30 30 A D T 3 S+ 0 0 61 -2,-0.2 2,-0.6 149,-0.1 -1,-0.3 0.344 118.1 97.5 -99.7 9.8 1.7 101.1 24.0 31 31 A T E < -C 28 0A 28 -3,-2.4 -3,-2.4 148,-0.0 2,-0.4 -0.874 64.7-145.9-103.2 119.8 0.2 104.6 23.5 32 32 A Q E +C 27 0A 39 -2,-0.6 -5,-0.3 -5,-0.2 3,-0.1 -0.687 24.1 169.9 -80.4 131.5 1.8 106.8 20.8 33 33 A F E + 0 0 0 -7,-2.0 15,-3.5 -2,-0.4 16,-0.9 0.652 56.6 27.2-117.3 -26.8 1.6 110.4 21.9 34 34 A V E +CD 26 47A 0 -8,-0.9 -8,-2.5 13,-0.3 2,-0.3 -0.962 56.2 176.6-137.5 158.6 3.8 112.4 19.5 35 35 A R E -CD 25 46A 28 11,-2.1 11,-3.5 -2,-0.3 2,-0.3 -0.992 10.7-163.2-156.0 154.9 5.1 112.2 15.9 36 36 A F E -C 24 0A 6 -12,-2.1 -12,-1.2 -2,-0.3 2,-0.3 -0.991 5.2-175.3-138.2 145.2 7.1 114.1 13.4 37 37 A D E > -C 23 0A 14 -2,-0.3 3,-2.6 7,-0.3 6,-0.4 -0.897 20.9-153.1-147.5 113.3 7.3 113.6 9.6 38 38 A S T 3 S+ 0 0 11 -16,-2.0 -15,-0.1 -2,-0.3 -19,-0.1 0.565 101.0 56.4 -60.7 -8.6 9.6 115.6 7.4 39 39 A D T 3 S+ 0 0 87 -17,-0.3 -1,-0.3 -3,-0.0 -16,-0.1 0.490 90.7 95.3 -99.9 -7.5 7.1 115.1 4.6 40 40 A A S < S- 0 0 24 -3,-2.6 -4,-0.0 1,-0.1 0, 0.0 -0.259 79.4-120.3 -80.6 172.2 4.3 116.7 6.5 41 41 A A S S+ 0 0 103 1,-0.1 -1,-0.1 2,-0.1 -3,-0.0 0.780 101.9 57.1 -84.9 -28.0 3.1 120.3 6.3 42 42 A S S S- 0 0 21 2,-0.1 -1,-0.1 -5,-0.1 3,-0.1 0.855 75.9-157.1 -73.7 -34.8 3.6 121.5 9.9 43 43 A Q + 0 0 74 -6,-0.4 2,-0.3 1,-0.3 -5,-0.1 0.887 60.1 108.8 56.2 38.8 7.3 120.7 10.2 44 44 A R S S- 0 0 143 -7,-0.1 2,-0.4 -9,-0.1 -7,-0.3 -0.926 86.7 -90.6-137.5 160.1 6.6 120.6 14.0 45 45 A M - 0 0 7 15,-0.5 -9,-0.2 -2,-0.3 19,-0.2 -0.643 55.3-151.4 -72.0 126.8 6.4 117.8 16.5 46 46 A E E -D 35 0A 39 -11,-3.5 -11,-2.1 -2,-0.4 2,-0.2 -0.676 8.8-111.2-104.7 159.9 2.8 116.8 16.4 47 47 A P E +D 34 0A 46 0, 0.0 -13,-0.3 0, 0.0 -14,-0.1 -0.589 29.6 169.7 -86.0 145.2 0.3 115.4 19.0 48 48 A R + 0 0 100 -15,-3.5 -14,-0.2 -2,-0.2 -16,-0.1 0.276 65.0 56.8-136.7 9.0 -1.1 111.8 18.8 49 49 A A S >> S- 0 0 5 -16,-0.9 3,-1.8 1,-0.1 4,-0.6 -0.993 78.3-128.3-141.5 132.3 -2.7 111.4 22.2 50 50 A P G >4 S+ 0 0 119 0, 0.0 3,-1.8 0, 0.0 4,-0.2 0.900 105.5 55.5 -44.6 -52.8 -5.4 113.6 23.7 51 51 A W G >4 S+ 0 0 16 1,-0.3 3,-1.4 2,-0.2 4,-0.1 0.630 90.1 72.7 -60.5 -16.8 -3.6 114.2 27.0 52 52 A I G X4 S+ 0 0 0 -3,-1.8 3,-2.5 1,-0.3 -1,-0.3 0.829 82.9 72.2 -69.1 -26.0 -0.5 115.5 25.4 53 53 A E G << S+ 0 0 112 -3,-1.8 -1,-0.3 -4,-0.6 -2,-0.2 0.609 76.5 79.6 -61.6 -12.0 -2.5 118.7 24.6 54 54 A Q G < S+ 0 0 114 -3,-1.4 -1,-0.3 -4,-0.2 -2,-0.2 0.642 77.6 96.6 -70.0 -12.3 -2.2 119.4 28.3 55 55 A E S < S- 0 0 16 -3,-2.5 -3,-0.0 1,-0.1 5,-0.0 -0.371 77.8-117.2 -75.9 158.0 1.2 120.6 27.4 56 56 A G >> - 0 0 37 -2,-0.1 3,-1.2 1,-0.1 4,-1.1 -0.257 29.1 -94.0 -89.4 178.6 1.9 124.3 26.8 57 57 A P H 3> S+ 0 0 107 0, 0.0 4,-2.0 0, 0.0 5,-0.2 0.867 122.1 58.5 -60.1 -37.6 3.2 126.2 23.8 58 58 A E H 3> S+ 0 0 168 1,-0.2 4,-1.9 2,-0.2 5,-0.1 0.691 98.0 62.6 -68.2 -16.0 6.8 126.1 24.8 59 59 A Y H <> S+ 0 0 16 -3,-1.2 4,-2.9 2,-0.2 5,-0.3 0.947 106.2 42.8 -71.6 -49.3 6.5 122.3 24.8 60 60 A W H X S+ 0 0 38 -4,-1.1 4,-1.9 2,-0.2 -15,-0.5 0.861 113.4 51.5 -65.6 -36.6 5.8 122.2 21.1 61 61 A D H X S+ 0 0 113 -4,-2.0 4,-2.1 2,-0.2 -1,-0.2 0.958 115.3 44.2 -63.6 -46.9 8.5 124.8 20.3 62 62 A G H X S+ 0 0 15 -4,-1.9 4,-2.6 1,-0.2 -2,-0.2 0.919 114.0 45.6 -63.7 -49.1 11.0 122.8 22.3 63 63 A E H X S+ 0 0 4 -4,-2.9 4,-2.5 2,-0.2 -1,-0.2 0.833 112.6 52.7 -66.3 -32.4 10.1 119.3 21.0 64 64 A T H X S+ 0 0 11 -4,-1.9 4,-2.0 -5,-0.3 -1,-0.2 0.946 111.5 46.0 -66.7 -47.7 10.0 120.6 17.4 65 65 A R H X S+ 0 0 130 -4,-2.1 4,-1.7 -5,-0.2 -2,-0.2 0.923 115.5 46.0 -60.1 -46.4 13.5 122.1 17.8 66 66 A K H X S+ 0 0 20 -4,-2.6 4,-1.6 1,-0.2 -1,-0.2 0.908 112.0 50.7 -65.2 -42.3 14.9 119.0 19.4 67 67 A V H X S+ 0 0 0 -4,-2.5 4,-1.9 1,-0.2 -1,-0.2 0.831 109.5 50.4 -66.0 -32.4 13.3 116.6 16.9 68 68 A K H X S+ 0 0 88 -4,-2.0 4,-2.6 2,-0.2 -1,-0.2 0.850 106.6 55.6 -72.9 -33.6 14.8 118.7 14.0 69 69 A A H X S+ 0 0 28 -4,-1.7 4,-1.5 2,-0.2 -2,-0.2 0.863 106.6 51.3 -64.1 -36.5 18.1 118.5 15.7 70 70 A H H X S+ 0 0 0 -4,-1.6 4,-2.7 2,-0.2 5,-0.2 0.921 108.5 50.3 -65.2 -46.2 17.7 114.7 15.6 71 71 A S H X S+ 0 0 28 -4,-1.9 4,-2.3 1,-0.2 -2,-0.2 0.937 108.6 53.5 -58.0 -46.2 16.9 114.8 11.9 72 72 A Q H X S+ 0 0 136 -4,-2.6 4,-1.1 1,-0.2 -1,-0.2 0.839 110.7 45.9 -59.0 -35.1 20.0 116.9 11.3 73 73 A T H X S+ 0 0 11 -4,-1.5 4,-2.5 2,-0.2 3,-0.4 0.943 112.0 50.0 -73.6 -47.2 22.2 114.3 13.1 74 74 A H H X S+ 0 0 0 -4,-2.7 4,-1.9 1,-0.2 -2,-0.2 0.829 107.0 57.3 -57.1 -35.1 20.7 111.4 11.3 75 75 A R H X S+ 0 0 131 -4,-2.3 4,-1.1 -5,-0.2 -1,-0.2 0.880 109.7 43.3 -65.5 -38.4 21.3 113.2 8.1 76 76 A V H X S+ 0 0 58 -4,-1.1 4,-3.1 -3,-0.4 -2,-0.2 0.882 111.1 54.7 -74.7 -39.0 25.0 113.5 8.8 77 77 A D H X S+ 0 0 0 -4,-2.5 4,-3.7 2,-0.2 5,-0.3 0.845 100.3 60.1 -63.2 -34.7 25.2 109.9 10.0 78 78 A L H X S+ 0 0 15 -4,-1.9 4,-1.6 2,-0.2 -1,-0.2 0.954 112.6 39.5 -56.9 -47.9 23.7 108.6 6.7 79 79 A G H X S+ 0 0 33 -4,-1.1 4,-2.2 2,-0.2 3,-0.4 0.981 115.9 50.9 -63.2 -57.0 26.6 110.2 5.0 80 80 A T H X S+ 0 0 39 -4,-3.1 4,-2.3 1,-0.3 -2,-0.2 0.879 112.5 45.3 -48.4 -49.1 29.2 109.2 7.6 81 81 A L H X S+ 0 0 0 -4,-3.7 4,-2.4 2,-0.2 -1,-0.3 0.843 106.8 60.4 -68.1 -30.3 28.1 105.5 7.6 82 82 A R H <>S+ 0 0 76 -4,-1.6 5,-1.8 -3,-0.4 -2,-0.2 0.973 109.0 43.1 -58.7 -52.7 28.1 105.5 3.8 83 83 A G H ><5S+ 0 0 33 -4,-2.2 3,-2.4 1,-0.2 -2,-0.2 0.942 110.4 56.4 -56.2 -51.8 31.7 106.4 3.9 84 84 A Y H 3<5S+ 0 0 89 -4,-2.3 -1,-0.2 1,-0.3 -2,-0.2 0.877 114.3 37.9 -47.4 -48.7 32.5 103.9 6.7 85 85 A Y T 3<5S- 0 0 69 -4,-2.4 -1,-0.3 -5,-0.1 -2,-0.2 0.269 110.2-126.2 -89.7 12.2 31.1 101.0 4.7 86 86 A N T < 5 + 0 0 147 -3,-2.4 2,-0.3 1,-0.1 -3,-0.2 0.914 52.8 159.0 41.5 64.2 32.5 102.4 1.5 87 87 A Q < - 0 0 54 -5,-1.8 -1,-0.1 -6,-0.1 2,-0.1 -0.757 44.9 -90.2-114.2 160.9 29.2 102.4 -0.4 88 88 A S - 0 0 81 -2,-0.3 3,-0.4 1,-0.1 -1,-0.1 -0.367 25.8-130.7 -69.9 147.1 27.9 104.3 -3.5 89 89 A E S S+ 0 0 144 1,-0.2 -1,-0.1 -2,-0.1 -6,-0.0 0.335 98.3 72.2 -77.9 8.4 26.2 107.6 -3.0 90 90 A A S S+ 0 0 77 2,-0.1 -1,-0.2 -74,-0.0 2,-0.0 0.875 79.5 77.5 -92.2 -42.5 23.4 106.4 -5.2 91 91 A G S S- 0 0 31 -3,-0.4 2,-0.4 1,-0.1 -78,-0.0 -0.229 80.6-108.5 -74.4 159.6 21.6 103.8 -3.1 92 92 A S - 0 0 61 -78,-0.1 2,-0.4 -80,-0.1 -78,-0.1 -0.712 36.4-174.0 -87.3 127.4 19.1 104.3 -0.3 93 93 A H - 0 0 14 -2,-0.4 -80,-2.3 215,-0.0 2,-0.3 -0.946 12.4-138.2-125.0 146.9 20.3 103.4 3.2 94 94 A T E -A 12 0A 2 -2,-0.4 25,-2.1 -82,-0.2 2,-0.4 -0.813 11.6-171.0-109.0 144.6 18.4 103.3 6.5 95 95 A V E -AE 11 118A 0 -84,-2.5 -84,-3.0 -2,-0.3 2,-0.4 -0.999 10.6-172.7-129.5 126.9 19.3 104.5 10.0 96 96 A Q E -AE 10 117A 0 21,-1.7 21,-2.9 -2,-0.4 2,-0.4 -0.954 2.8-177.1-123.0 142.7 17.1 103.6 12.9 97 97 A R E +AE 9 116A 1 -88,-2.6 -88,-3.5 -2,-0.4 2,-0.3 -0.999 4.0 175.2-141.4 141.6 17.4 104.8 16.5 98 98 A M E +AE 8 115A 26 17,-2.4 17,-3.1 -2,-0.4 2,-0.3 -0.987 8.4 154.7-143.5 147.4 15.5 103.9 19.7 99 99 A Y E +AE 7 114A 0 -92,-1.5 -92,-2.6 -2,-0.3 2,-0.3 -0.964 9.7 123.1-166.6 158.4 15.8 105.0 23.3 100 100 A G E -AE 6 113A 0 13,-2.0 13,-2.0 -2,-0.3 2,-0.3 -0.986 40.9 -98.8 170.2-168.3 13.8 105.4 26.5 101 101 A a E -AE 5 112A 0 -96,-1.8 -96,-1.9 -2,-0.3 2,-0.3 -0.986 15.4-140.6-145.8 153.4 13.4 104.4 30.1 102 102 A D E -AE 4 111A 21 9,-3.1 8,-3.0 -2,-0.3 9,-0.9 -0.878 15.5-167.3-112.8 146.4 11.4 102.0 32.2 103 103 A V E -AE 3 109A 0 -100,-3.1 -100,-2.3 -2,-0.3 6,-0.2 -0.981 16.8-124.9-133.4 147.7 9.9 102.6 35.7 104 104 A G > - 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