==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=13-MAY-2012 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER LYASE/LYASE INHIBITOR 05-JUN-11 3SBI . COMPND 2 MOLECULE: CARBONIC ANHYDRASE 2; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR S.GRAZULIS,E.MANAKOVA,G.TAMULAITIENE . 258 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 11976.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 167 64.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 16 6.2 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 56 21.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 3 1.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 25 9.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 35 13.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 17 6.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 2 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 3 1 1 1 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 3 A H 0 0 176 0, 0.0 2,-0.1 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 66.6 13.5 -1.1 7.6 2 4 A H - 0 0 125 1,-0.2 0, 0.0 15,-0.0 0, 0.0 -0.396 360.0 -79.2 -89.9 169.0 10.2 0.1 8.9 3 5 A W + 0 0 45 -2,-0.1 2,-0.2 1,-0.1 7,-0.2 -0.199 62.6 130.7 -65.3 155.1 7.8 -1.6 11.3 4 6 A G - 0 0 6 5,-2.5 10,-0.1 2,-0.1 -1,-0.1 -0.783 66.1 -62.3-168.9-153.9 5.4 -4.3 10.3 5 7 A Y S S+ 0 0 36 -2,-0.2 2,-0.2 5,-0.2 5,-0.1 -0.267 88.0 99.9-114.9 46.3 4.2 -7.8 11.1 6 8 A G S > S- 0 0 28 1,-0.0 4,-2.8 0, 0.0 -2,-0.1 -0.644 81.9 -98.3-124.9 178.9 7.5 -10.0 10.7 7 9 A K T 4 S+ 0 0 158 1,-0.2 5,-0.0 2,-0.2 -1,-0.0 0.905 125.5 35.5 -55.4 -41.2 10.4 -11.7 12.5 8 10 A H T 4 S+ 0 0 127 1,-0.1 -1,-0.2 4,-0.0 -5,-0.0 0.667 135.6 19.2 -94.5 -22.7 12.6 -8.9 11.7 9 11 A N T 4 S+ 0 0 42 -6,-0.1 -5,-2.5 3,-0.0 -2,-0.2 0.260 95.6 114.5-135.1 17.7 10.1 -5.9 12.0 10 12 A G S >X S- 0 0 0 -4,-2.8 3,-2.7 -7,-0.2 4,-0.6 0.167 84.6 -64.5 -84.4-173.3 7.2 -7.2 14.1 11 13 A P G >4 S+ 0 0 28 0, 0.0 3,-0.9 0, 0.0 4,-0.4 0.777 127.0 61.4 -43.7 -35.1 5.8 -6.4 17.5 12 14 A E G 34 S+ 0 0 117 1,-0.2 -2,-0.1 2,-0.1 -5,-0.1 0.554 108.8 44.3 -73.9 -6.0 8.8 -7.5 19.4 13 15 A H G X> S+ 0 0 50 -3,-2.7 3,-1.8 1,-0.1 4,-0.5 0.500 85.1 91.4-108.0 -16.1 11.0 -4.9 17.6 14 16 A W H XX S+ 0 0 5 -3,-0.9 4,-2.5 -4,-0.6 3,-0.8 0.796 72.1 71.4 -62.6 -26.6 8.7 -1.8 17.8 15 17 A H H 34 S+ 0 0 67 -4,-0.4 -1,-0.3 1,-0.3 7,-0.1 0.731 87.9 64.7 -60.7 -29.4 10.2 -0.6 21.1 16 18 A K H <4 S+ 0 0 132 -3,-1.8 -1,-0.3 1,-0.2 -2,-0.2 0.905 117.5 25.2 -66.5 -38.4 13.5 0.4 19.3 17 19 A D H << S+ 0 0 113 -3,-0.8 -2,-0.2 -4,-0.5 -1,-0.2 0.749 136.4 34.0 -89.8 -23.5 11.7 3.1 17.2 18 20 A F >< - 0 0 56 -4,-2.5 3,-2.6 1,-0.1 -1,-0.2 -0.805 65.5-176.1-132.6 78.9 8.8 3.7 19.6 19 21 A P G > S+ 0 0 103 0, 0.0 3,-1.9 0, 0.0 -4,-0.1 0.732 76.9 76.3 -57.3 -22.4 10.0 3.3 23.2 20 22 A I G > + 0 0 69 1,-0.3 3,-2.9 179,-0.2 5,-0.2 0.668 69.9 89.8 -59.0 -14.1 6.4 3.8 24.6 21 23 A A G < S+ 0 0 7 -3,-2.6 -1,-0.3 1,-0.3 -6,-0.1 0.750 90.9 44.6 -50.5 -25.8 5.9 0.2 23.4 22 24 A K G < S+ 0 0 141 -3,-1.9 -1,-0.3 -4,-0.1 -2,-0.2 0.054 96.4 129.1-107.2 28.0 7.1 -0.7 27.0 23 25 A G S X S- 0 0 12 -3,-2.9 3,-0.5 1,-0.1 -3,-0.1 0.120 72.8-101.3 -77.7-173.9 4.9 2.0 28.6 24 26 A E T 3 S+ 0 0 122 1,-0.2 226,-0.3 225,-0.1 -1,-0.1 0.549 112.1 36.0 -90.4 -6.6 2.4 1.8 31.5 25 27 A R T 3 S+ 0 0 47 -5,-0.2 -1,-0.2 224,-0.1 2,-0.2 -0.338 78.2 153.9-144.5 57.1 -0.9 1.7 29.4 26 28 A Q < - 0 0 3 -3,-0.5 220,-0.2 221,-0.4 170,-0.1 -0.570 33.4-102.6 -88.7 151.7 -0.2 -0.3 26.3 27 29 A S S S+ 0 0 0 168,-0.5 2,-0.2 -2,-0.2 -2,-0.0 -0.879 77.2 42.3-124.8 159.8 -2.8 -2.3 24.4 28 30 A P + 0 0 0 0, 0.0 218,-2.7 0, 0.0 2,-0.3 0.618 65.1 178.0 -77.9-175.8 -4.1 -4.8 23.7 29 31 A V - 0 0 1 216,-0.3 77,-1.2 -2,-0.2 2,-0.4 -0.906 36.2-100.6-140.4 159.9 -4.5 -6.8 27.0 30 32 A D E -a 106 0A 30 216,-0.4 2,-0.8 -2,-0.3 77,-0.2 -0.723 34.4-138.6 -77.4 134.9 -5.9 -10.1 28.1 31 33 A I E -a 107 0A 0 75,-2.9 77,-2.9 -2,-0.4 2,-1.0 -0.853 11.3-159.3 -97.9 105.2 -9.4 -9.6 29.6 32 34 A D >> - 0 0 63 -2,-0.8 4,-1.0 75,-0.2 3,-0.7 -0.795 5.9-160.5 -88.4 104.7 -9.6 -11.8 32.7 33 35 A T T 34 S+ 0 0 42 -2,-1.0 -1,-0.2 1,-0.3 222,-0.0 0.740 83.8 55.8 -66.5 -26.5 -13.3 -12.0 33.0 34 36 A H T 34 S+ 0 0 163 1,-0.2 -1,-0.3 -3,-0.1 -2,-0.0 0.841 112.2 42.0 -73.9 -33.1 -13.3 -13.1 36.6 35 37 A T T <4 S+ 0 0 99 -3,-0.7 2,-0.3 2,-0.1 -2,-0.2 0.429 86.0 106.6 -96.1 -5.1 -11.2 -10.2 37.8 36 38 A A S < S- 0 0 16 -4,-1.0 2,-0.5 216,-0.1 218,-0.2 -0.598 72.9-129.3 -66.1 133.6 -13.0 -7.5 35.7 37 39 A K E -c 254 0B 135 216,-2.1 218,-2.4 -2,-0.3 2,-0.2 -0.826 9.5-127.8 -91.3 126.4 -15.1 -5.4 38.2 38 40 A Y E -c 255 0B 102 -2,-0.5 218,-0.2 216,-0.2 220,-0.1 -0.489 25.8-160.1 -62.4 133.7 -18.8 -4.9 37.4 39 41 A D > - 0 0 31 216,-2.6 3,-1.8 -2,-0.2 -1,-0.0 -0.925 14.3-168.5-124.8 104.4 -19.3 -1.1 37.7 40 42 A P T 3 S+ 0 0 98 0, 0.0 -1,-0.1 0, 0.0 216,-0.0 0.655 85.7 67.7 -64.6 -18.7 -22.9 -0.1 38.2 41 43 A S T 3 S+ 0 0 90 2,-0.1 2,-0.2 40,-0.0 215,-0.1 0.507 77.6 103.9 -76.5 -7.4 -21.9 3.6 37.6 42 44 A L < - 0 0 29 -3,-1.8 3,-0.1 213,-0.2 38,-0.0 -0.537 66.2-137.9 -73.7 142.8 -21.2 2.7 33.9 43 45 A K - 0 0 130 37,-1.0 39,-0.1 -2,-0.2 -2,-0.1 -0.586 27.3 -88.6 -97.8 158.0 -23.8 3.9 31.3 44 46 A P - 0 0 115 0, 0.0 36,-2.1 0, 0.0 2,-0.3 -0.390 53.3-105.2 -54.5 144.1 -25.2 2.1 28.3 45 47 A L E -D 79 0B 12 141,-0.3 2,-0.6 34,-0.3 34,-0.2 -0.635 28.8-145.9 -75.4 139.5 -23.0 2.8 25.3 46 48 A S E -D 78 0B 31 32,-2.8 32,-2.2 -2,-0.3 2,-0.6 -0.931 18.5-179.7-111.6 108.3 -24.7 5.2 22.8 47 49 A V E -D 77 0B 33 -2,-0.6 2,-0.6 30,-0.2 30,-0.2 -0.944 2.7-178.7-110.2 113.7 -23.8 4.5 19.2 48 50 A S E +D 76 0B 41 28,-2.7 28,-1.9 -2,-0.6 3,-0.2 -0.797 23.0 145.1-119.8 90.1 -25.3 6.9 16.7 49 51 A Y > + 0 0 3 -2,-0.6 3,-2.0 26,-0.2 130,-0.2 0.323 33.6 111.8-107.2 5.7 -24.3 5.8 13.2 50 52 A D T 3 S+ 0 0 91 1,-0.3 -1,-0.1 127,-0.1 25,-0.1 0.711 87.6 36.0 -55.1 -26.6 -27.6 6.7 11.4 51 53 A Q T 3 S+ 0 0 124 23,-1.0 -1,-0.3 -3,-0.2 24,-0.1 0.156 82.7 145.2-113.8 22.3 -25.9 9.6 9.4 52 54 A A < - 0 0 24 -3,-2.0 2,-0.5 1,-0.1 23,-0.1 -0.255 33.1-158.3 -62.5 139.7 -22.5 8.0 8.9 53 55 A T - 0 0 48 16,-0.4 16,-2.9 122,-0.1 2,-0.2 -0.882 4.4-164.6-121.6 96.4 -20.8 9.0 5.5 54 56 A S E +E 68 0B 1 -2,-0.5 121,-0.6 122,-0.3 14,-0.3 -0.526 10.1 177.0 -74.4 154.4 -18.1 6.6 4.4 55 57 A L E - 0 0 81 12,-3.2 118,-2.2 1,-0.4 2,-0.3 0.679 50.6 -9.1-120.5 -46.2 -15.9 7.9 1.7 56 58 A R E -EF 67 172B 82 11,-1.0 11,-3.1 116,-0.3 -1,-0.4 -0.988 47.8-131.6-159.2 156.5 -13.1 5.5 0.7 57 59 A I E -EF 66 171B 0 114,-2.5 114,-2.1 -2,-0.3 2,-0.4 -0.985 26.9-169.4-123.9 140.0 -11.3 2.3 1.5 58 60 A L E -EF 65 170B 34 7,-2.0 7,-2.7 -2,-0.4 2,-0.8 -0.989 24.5-145.0-135.5 130.8 -7.5 2.2 1.7 59 61 A N E -E 64 0B 0 110,-2.7 109,-2.7 -2,-0.4 5,-0.2 -0.887 22.2-177.9 -90.9 111.8 -4.8 -0.6 1.9 60 62 A N - 0 0 56 3,-2.0 4,-0.1 -2,-0.8 -1,-0.1 0.253 51.6-100.7 -97.3 10.6 -2.3 1.1 4.1 61 63 A G S S+ 0 0 6 2,-0.5 106,-0.1 166,-0.2 3,-0.1 0.357 117.7 54.0 86.0 -6.0 0.2 -1.7 4.0 62 64 A H S S- 0 0 40 1,-0.6 2,-0.2 -58,-0.1 -1,-0.1 0.641 125.0 -31.4-124.9 -35.2 -0.8 -3.0 7.5 63 65 A A S S- 0 0 6 -5,-0.1 -3,-2.0 31,-0.1 -1,-0.6 -0.804 72.9 -85.8-160.7-169.4 -4.6 -3.4 7.2 64 66 A F E -E 59 0B 0 29,-0.3 2,-0.5 -2,-0.2 29,-0.4 -0.989 34.9-151.7-116.5 143.5 -7.4 -1.8 5.3 65 67 A N E -E 58 0B 25 -7,-2.7 -7,-2.0 -2,-0.4 2,-0.6 -0.905 6.6-154.4-111.6 128.2 -9.2 1.4 6.6 66 68 A V E -EG 57 91B 0 25,-2.8 25,-1.8 -2,-0.5 2,-0.3 -0.927 29.0-152.3 -93.5 120.0 -12.7 2.3 5.8 67 69 A E E -EG 56 90B 42 -11,-3.1 -12,-3.2 -2,-0.6 -11,-1.0 -0.713 10.6-157.8-104.7 150.1 -12.7 6.1 6.2 68 70 A F E -E 54 0B 9 21,-2.6 2,-0.7 -2,-0.3 -14,-0.2 -0.825 29.5-102.9-122.4 157.6 -15.5 8.4 7.1 69 71 A D + 0 0 31 -16,-2.9 -16,-0.4 -2,-0.3 5,-0.2 -0.667 40.6 170.9 -70.0 115.9 -16.4 12.1 6.7 70 72 A D + 0 0 41 -2,-0.7 -1,-0.1 1,-0.1 17,-0.1 0.021 45.5 104.2-115.7 30.3 -15.6 13.4 10.2 71 73 A S S S+ 0 0 85 2,-0.0 2,-0.3 56,-0.0 -1,-0.1 0.451 86.8 30.3 -92.5 2.9 -16.0 17.1 9.4 72 74 A Q S S- 0 0 115 -3,-0.2 2,-1.5 3,-0.0 3,-0.3 -0.956 101.1 -88.4-148.7 166.1 -19.4 17.3 11.1 73 75 A D S S+ 0 0 92 -2,-0.3 3,-0.1 1,-0.2 -3,-0.1 -0.620 78.0 124.4 -84.2 87.0 -21.1 15.5 14.0 74 76 A K + 0 0 50 -2,-1.5 -23,-1.0 1,-0.3 2,-0.3 0.522 67.4 28.7-113.7 -30.6 -22.6 12.5 12.1 75 77 A A S S+ 0 0 5 -3,-0.3 13,-3.2 -24,-0.1 2,-0.4 -0.803 82.2 169.5-139.6 97.3 -21.5 9.1 13.4 76 78 A V E -DH 48 87B 19 -28,-1.9 -28,-2.7 -2,-0.3 2,-0.4 -0.918 30.1-153.0-128.3 150.6 -20.7 9.5 17.1 77 79 A L E +DH 47 86B 0 9,-2.9 9,-2.1 -2,-0.4 2,-0.3 -0.941 32.0 144.1-109.5 136.6 -20.0 7.4 20.2 78 80 A K E +D 46 0B 93 -32,-2.2 -32,-2.8 -2,-0.4 7,-0.1 -0.872 37.7 43.1-158.1-179.3 -20.9 8.7 23.6 79 81 A G E > S+D 45 0B 17 5,-0.4 3,-2.4 3,-0.3 -34,-0.3 -0.348 73.5 89.3 71.5-154.3 -22.1 7.4 27.0 80 82 A G T 3 S- 0 0 4 -36,-2.1 -37,-1.0 1,-0.3 -1,-0.1 -0.379 120.8 -29.7 64.7-138.7 -20.6 4.2 28.2 81 83 A P T 3 S+ 0 0 42 0, 0.0 -1,-0.3 0, 0.0 2,-0.2 0.454 115.6 112.3 -84.1 1.4 -17.4 5.2 30.3 82 84 A L < - 0 0 14 -3,-2.4 2,-0.5 -39,-0.1 -3,-0.3 -0.443 57.2-149.5 -87.7 150.9 -17.0 8.4 28.1 83 85 A D S S- 0 0 143 -2,-0.2 2,-0.0 -5,-0.1 -1,-0.0 -0.920 71.7 -10.4-103.3 131.1 -17.3 12.1 29.0 84 86 A G S S- 0 0 53 -2,-0.5 -5,-0.4 38,-0.1 2,-0.4 -0.322 98.5 -41.4 78.4-166.9 -18.4 14.0 26.0 85 87 A T - 0 0 39 -7,-0.1 38,-2.3 -2,-0.0 2,-0.4 -0.840 39.1-163.8-115.7 137.2 -18.7 13.1 22.2 86 88 A Y E -HI 77 122B 6 -9,-2.1 -9,-2.9 -2,-0.4 2,-0.4 -0.996 13.5-143.5-125.2 132.9 -16.4 11.1 20.0 87 89 A R E -HI 76 121B 35 34,-2.7 34,-2.1 -2,-0.4 2,-0.3 -0.769 20.0-117.1-101.8 132.1 -16.6 11.1 16.2 88 90 A L E + I 0 120B 1 -13,-3.2 32,-0.3 -2,-0.4 -14,-0.1 -0.504 37.6 165.5 -63.7 127.8 -16.0 8.1 14.0 89 91 A I E - 0 0 36 30,-2.8 -21,-2.6 1,-0.4 2,-0.3 0.735 60.4 -24.4-109.7 -39.3 -13.0 8.6 11.6 90 92 A Q E -GI 67 119B 33 29,-1.2 29,-2.9 -23,-0.3 -1,-0.4 -0.971 47.1-144.2-163.7 158.3 -12.3 5.0 10.4 91 93 A F E +GI 66 118B 0 -25,-1.8 -25,-2.8 -2,-0.3 2,-0.3 -0.955 22.9 162.3-127.9 161.3 -12.6 1.3 11.0 92 94 A H E - I 0 117B 25 25,-1.8 25,-3.1 -2,-0.3 2,-0.3 -0.929 23.5-126.6-156.0 174.5 -10.2 -1.5 10.3 93 95 A F E - I 0 116B 0 -29,-0.4 2,-0.4 -2,-0.3 -29,-0.3 -0.844 0.5-148.1-127.4 163.9 -9.6 -5.1 11.3 94 96 A H E + I 0 115B 3 21,-2.0 21,-2.2 -2,-0.3 2,-0.3 -0.981 31.7 168.0-123.2 140.2 -6.8 -7.4 12.6 95 97 A W E - I 0 114B 0 -2,-0.4 146,-1.3 19,-0.2 145,-0.9 -0.944 24.3-114.6-150.4 173.8 -6.8 -11.0 11.6 96 98 A G - 0 0 0 17,-1.4 6,-0.1 5,-0.6 3,-0.1 -0.415 23.7-121.2-108.0 177.3 -4.9 -14.3 11.5 97 99 A S S S+ 0 0 43 142,-0.2 2,-0.3 -2,-0.1 5,-0.1 0.606 105.8 28.7 -82.7 -14.6 -3.4 -16.8 9.1 98 100 A L S > S- 0 0 104 3,-0.3 3,-1.7 15,-0.1 -2,-0.2 -0.957 90.3-108.3-141.5 160.7 -5.7 -19.4 10.7 99 101 A D T 3 S+ 0 0 77 -2,-0.3 48,-0.1 1,-0.3 15,-0.1 0.749 109.6 68.9 -67.2 -23.8 -9.1 -19.2 12.4 100 102 A G T 3 S+ 0 0 56 13,-0.1 2,-0.3 2,-0.1 -1,-0.3 0.390 107.0 26.7 -75.8 4.5 -7.5 -19.9 15.8 101 103 A Q < + 0 0 51 -3,-1.7 -5,-0.6 12,-0.1 -3,-0.3 -0.973 64.9 100.4-154.3 167.1 -5.8 -16.6 16.1 102 104 A G + 0 0 0 1,-0.6 13,-0.3 -2,-0.3 11,-0.2 -0.019 54.6 109.2 142.2 -31.2 -6.1 -12.9 14.8 103 105 A S - 0 0 1 9,-2.0 -1,-0.6 11,-0.3 -8,-0.1 -0.408 51.4-154.7 -71.7 158.2 -7.7 -11.0 17.7 104 106 A E S S+ 0 0 1 -10,-0.1 -1,-0.1 -3,-0.1 2,-0.1 0.870 83.4 52.0 -94.2 -59.1 -5.6 -8.4 19.6 105 107 A H S S- 0 0 0 -77,-0.1 7,-0.4 -75,-0.1 2,-0.3 -0.481 77.8-158.6 -68.9 154.2 -7.6 -8.5 22.8 106 108 A T E -a 30 0A 10 -77,-1.2 -75,-2.9 -2,-0.1 2,-0.5 -0.881 11.1-138.6-128.5 160.6 -8.1 -12.0 24.3 107 109 A V E > S-aB 31 110A 18 3,-1.7 3,-2.5 -2,-0.3 -75,-0.2 -0.973 88.3 -20.8-124.7 113.4 -10.8 -13.2 26.8 108 110 A D T 3 S- 0 0 66 -77,-2.9 -1,-0.1 -2,-0.5 -76,-0.1 0.902 129.1 -54.5 45.7 45.5 -9.5 -15.5 29.4 109 111 A K T 3 S+ 0 0 156 1,-0.3 2,-0.3 -78,-0.1 -1,-0.3 0.270 104.8 141.2 70.1 -0.1 -6.6 -16.1 26.9 110 112 A K B < -B 107 0A 113 -3,-2.5 -3,-1.7 -9,-0.0 2,-0.4 -0.508 40.4-150.4 -72.9 130.2 -9.1 -17.1 24.1 111 113 A K - 0 0 92 -2,-0.3 2,-0.2 -11,-0.2 -5,-0.1 -0.811 6.7-149.5 -93.4 133.3 -8.0 -15.7 20.7 112 114 A Y - 0 0 29 -7,-0.4 -9,-2.0 -2,-0.4 34,-0.2 -0.589 28.2-108.3 -93.6 167.7 -10.7 -14.9 18.2 113 115 A A S S- 0 0 5 32,-1.1 -17,-1.4 -11,-0.2 2,-0.3 0.760 93.2 -15.3 -67.7 -26.9 -10.3 -15.2 14.4 114 116 A A E -IJ 95 145B 1 31,-1.3 31,-2.4 -19,-0.2 2,-0.3 -0.977 57.8-136.5-164.4 173.8 -10.3 -11.4 14.0 115 117 A E E -IJ 94 144B 0 -21,-2.2 -21,-2.0 -13,-0.3 2,-0.4 -0.983 11.7-147.3-148.1 127.2 -11.1 -8.1 15.7 116 118 A L E -IJ 93 143B 0 27,-3.0 27,-2.4 -2,-0.3 2,-0.5 -0.822 11.4-160.3 -95.3 135.9 -12.8 -5.0 14.3 117 119 A H E -IJ 92 142B 2 -25,-3.1 -25,-1.8 -2,-0.4 2,-0.7 -0.972 6.1-165.4-120.2 117.5 -11.8 -1.5 15.6 118 120 A L E -IJ 91 141B 0 23,-2.6 23,-2.5 -2,-0.5 2,-0.5 -0.917 21.0-152.0-100.1 112.3 -14.1 1.5 15.1 119 121 A V E +IJ 90 140B 8 -29,-2.9 -30,-2.8 -2,-0.7 -29,-1.2 -0.823 18.9 175.4 -99.7 128.0 -11.9 4.5 15.9 120 122 A H E -IJ 88 139B 0 19,-2.1 19,-2.6 -2,-0.5 2,-0.3 -0.960 16.9-146.0-131.7 145.7 -13.4 7.8 17.2 121 123 A W E -IJ 87 138B 8 -34,-2.1 -34,-2.7 -2,-0.3 2,-0.4 -0.863 28.5-105.2-116.4 148.5 -11.8 11.1 18.4 122 124 A N E > -I 86 0B 4 15,-3.2 3,-2.3 -2,-0.3 -36,-0.2 -0.508 22.1-145.6 -73.1 119.5 -12.9 13.4 21.2 123 125 A T G > S+ 0 0 43 -38,-2.3 3,-1.3 -2,-0.4 -1,-0.2 0.664 91.7 77.3 -60.7 -18.0 -14.5 16.5 19.7 124 127 A K G 3 S+ 0 0 137 -39,-0.4 -1,-0.3 1,-0.2 -38,-0.1 0.687 93.7 53.9 -66.5 -10.7 -13.2 18.6 22.5 125 128 A Y G < S- 0 0 52 -3,-2.3 2,-1.3 12,-0.1 -1,-0.2 0.401 102.3-131.6-104.2 4.1 -9.8 18.5 20.7 126 129 A G S < S+ 0 0 56 -3,-1.3 2,-0.3 -4,-0.2 -3,-0.1 -0.094 74.4 17.0 83.1 -39.8 -11.0 19.7 17.2 127 130 A D S > S- 0 0 84 -2,-1.3 4,-2.2 -5,-0.2 3,-0.2 -0.972 79.7-100.8-158.4 168.8 -9.3 17.0 15.1 128 131 A F H > S+ 0 0 66 -2,-0.3 4,-2.1 1,-0.2 -6,-0.1 0.860 114.6 55.9 -58.7 -45.1 -7.8 13.5 15.2 129 132 A G H 4 S+ 0 0 39 1,-0.2 -1,-0.2 2,-0.2 4,-0.2 0.831 113.3 40.1 -65.5 -34.2 -4.2 14.7 15.1 130 133 A K H >4 S+ 0 0 114 -3,-0.2 3,-1.4 -5,-0.2 -1,-0.2 0.842 111.9 58.8 -74.4 -34.9 -4.6 16.9 18.2 131 134 A A H >< S+ 0 0 0 -4,-2.2 3,-1.9 1,-0.3 6,-0.3 0.863 95.4 61.2 -62.6 -36.0 -6.7 14.2 20.0 132 135 A V T 3< S+ 0 0 19 -4,-2.1 -1,-0.3 1,-0.3 -2,-0.1 0.647 96.2 63.3 -69.8 -8.1 -4.0 11.5 19.8 133 136 A Q T < S+ 0 0 131 -3,-1.4 -1,-0.3 -4,-0.2 -2,-0.2 0.310 94.7 76.5 -90.9 10.7 -1.8 13.8 21.9 134 137 A Q S X S- 0 0 65 -3,-1.9 3,-1.9 69,-0.1 4,-0.3 -0.921 81.0-129.0-125.2 147.3 -4.2 13.6 24.9 135 138 A P T 3 S+ 0 0 76 0, 0.0 58,-0.1 0, 0.0 3,-0.1 0.723 114.4 35.5 -71.2 -16.5 -4.9 10.8 27.4 136 139 A D T 3 S+ 0 0 50 1,-0.1 68,-0.1 -5,-0.1 67,-0.1 -0.155 88.0 113.7-117.6 34.6 -8.7 10.9 26.7 137 140 A G S < S+ 0 0 0 -3,-1.9 -15,-3.2 -6,-0.3 2,-0.3 0.801 71.2 34.3 -80.0 -31.9 -8.3 11.7 22.9 138 141 A L E -Jk 121 204B 0 65,-2.9 67,-2.6 -4,-0.3 2,-0.4 -0.896 52.6-160.6-124.8 154.4 -9.7 8.5 21.4 139 142 A A E -Jk 120 205B 0 -19,-2.6 -19,-2.1 -2,-0.3 2,-0.5 -0.995 14.4-166.8-128.3 120.5 -12.3 5.9 22.0 140 143 A V E -Jk 119 206B 4 65,-1.8 67,-2.5 -2,-0.4 2,-0.7 -0.967 8.6-153.1-109.6 124.8 -11.9 2.7 20.1 141 144 A L E -Jk 118 207B 0 -23,-2.5 -23,-2.6 -2,-0.5 2,-0.4 -0.871 16.6-161.4 -95.3 118.5 -14.9 0.2 20.0 142 145 A G E -Jk 117 208B 0 65,-2.9 67,-2.9 -2,-0.7 2,-0.4 -0.836 10.1-176.1-106.8 135.8 -13.5 -3.3 19.6 143 146 A I E -J 116 0B 0 -27,-2.4 -27,-3.0 -2,-0.4 2,-0.2 -0.993 20.0-131.9-134.3 128.8 -15.7 -6.2 18.4 144 147 A F E -J 115 0B 0 65,-0.4 69,-2.9 -2,-0.4 2,-0.4 -0.512 14.2-149.9 -77.1 150.7 -14.5 -9.8 18.1 145 148 A L E -Jl 114 213B 1 -31,-2.4 -31,-1.3 67,-0.2 -32,-1.1 -0.979 13.1-176.0-118.8 130.7 -15.1 -11.9 15.0 146 149 A K E - l 0 214B 105 67,-2.5 69,-2.5 -2,-0.4 2,-0.5 -0.859 31.7-109.2-116.4 156.9 -15.6 -15.7 15.1 147 150 A V E S+ l 0 215B 49 -2,-0.3 69,-0.2 67,-0.2 2,-0.2 -0.756 75.7 84.5 -90.2 123.4 -16.0 -18.0 12.0 148 151 A G S S+ 0 0 47 67,-3.1 69,-0.5 -2,-0.5 -1,-0.1 -0.537 79.3 23.4-170.1-119.7 -19.6 -19.4 11.5 149 152 A S S S- 0 0 91 -2,-0.2 -1,-0.5 67,-0.1 2,-0.1 -0.238 86.8-101.9 -59.3 148.6 -22.5 -17.8 9.8 150 153 A A - 0 0 55 65,-0.3 65,-0.2 -3,-0.1 64,-0.1 -0.492 23.3-129.0 -67.2 156.1 -21.8 -15.0 7.3 151 154 A K >> - 0 0 43 1,-0.2 3,-1.7 -2,-0.1 4,-0.6 -0.899 16.3-162.5-102.5 101.9 -22.3 -11.4 8.3 152 155 A P G >4 S+ 0 0 112 0, 0.0 3,-1.5 0, 0.0 4,-0.4 0.914 88.7 58.2 -56.1 -35.6 -24.4 -9.9 5.5 153 156 A G G 34 S+ 0 0 26 27,-0.4 27,-0.2 1,-0.3 4,-0.1 0.607 102.7 55.2 -70.5 -15.4 -23.4 -6.3 6.5 154 157 A L G X> S+ 0 0 1 -3,-1.7 4,-2.2 26,-0.1 3,-1.4 0.620 84.2 85.2 -83.7 -18.8 -19.8 -7.2 5.9 155 158 A Q H S+ 0 0 163 -4,-0.4 4,-0.5 1,-0.2 -1,-0.3 0.777 110.0 46.7 -63.3 -24.8 -19.8 -5.0 0.7 157 160 A V H X> S+ 0 0 0 -3,-1.4 3,-1.1 2,-0.2 4,-0.8 0.923 112.0 50.1 -77.6 -48.5 -16.4 -4.6 2.3 158 161 A V H >< S+ 0 0 4 -4,-2.2 3,-1.0 1,-0.3 4,-0.4 0.903 107.0 55.3 -57.3 -42.9 -15.3 -8.1 1.3 159 162 A D H 3< S+ 0 0 93 -4,-2.7 3,-0.3 1,-0.2 -1,-0.3 0.727 105.0 50.6 -66.4 -21.4 -16.3 -7.6 -2.3 160 163 A V H X< S+ 0 0 27 -3,-1.1 3,-1.6 -4,-0.5 4,-0.4 0.551 85.9 89.7 -91.4 -11.0 -14.1 -4.4 -2.8 161 164 A L G X< S+ 0 0 5 -3,-1.0 3,-1.6 -4,-0.8 -1,-0.2 0.825 76.4 62.2 -61.5 -30.9 -10.9 -6.0 -1.5 162 165 A D G > S+ 0 0 129 -4,-0.4 3,-0.7 -3,-0.3 -1,-0.3 0.796 99.8 57.3 -67.4 -20.2 -9.8 -7.3 -4.8 163 166 A S G < S+ 0 0 39 -3,-1.6 -1,-0.3 1,-0.2 -2,-0.2 0.545 113.2 39.3 -80.4 -9.8 -9.6 -3.7 -6.0 164 167 A I G < S+ 0 0 0 -3,-1.6 63,-0.3 -4,-0.4 -1,-0.2 -0.218 74.0 139.5-129.6 41.6 -7.2 -2.7 -3.1 165 168 A K < + 0 0 92 -3,-0.7 62,-2.7 61,-0.1 2,-0.2 0.868 60.6 46.4 -56.1 -37.4 -5.0 -5.8 -3.1 166 169 A T S > S- 0 0 11 60,-0.2 3,-2.2 1,-0.1 -107,-0.3 -0.622 97.9 -77.0-121.1 158.1 -1.6 -4.1 -2.5 167 170 A K T 3 S+ 0 0 81 62,-2.3 64,-0.5 1,-0.3 -107,-0.2 -0.207 113.9 22.7 -51.3 134.2 -0.2 -1.4 -0.3 168 171 A G T 3 S+ 0 0 57 -109,-2.7 2,-0.3 1,-0.3 -1,-0.3 0.231 89.8 128.2 89.2 -14.4 -1.1 2.1 -1.3 169 172 A K < + 0 0 82 -3,-2.2 -110,-2.7 -5,-0.1 2,-0.3 -0.539 32.0 177.8 -72.2 139.4 -4.3 1.2 -3.3 170 173 A S E -F 58 0B 58 -2,-0.3 2,-0.3 -112,-0.2 -112,-0.2 -0.923 9.3-168.4-134.4 162.7 -7.6 3.0 -2.5 171 174 A A E -F 57 0B 22 -114,-2.1 -114,-2.5 -2,-0.3 -116,-0.0 -0.991 35.3 -93.6-147.9 147.3 -11.2 2.9 -3.9 172 175 A D E +F 56 0B 141 -2,-0.3 -116,-0.3 -116,-0.2 2,-0.1 -0.315 41.9 176.7 -51.3 136.0 -14.4 4.9 -3.6 173 176 A F + 0 0 18 -118,-2.2 3,-0.4 -106,-0.1 -117,-0.2 -0.539 10.8 163.4-151.8 76.1 -16.5 3.4 -0.8 174 177 A T + 0 0 87 1,-0.2 -119,-0.2 -119,-0.2 -121,-0.1 -0.551 53.2 23.1 -92.7 160.6 -19.6 5.4 -0.3 175 178 A N S S+ 0 0 149 -121,-0.6 2,-0.5 1,-0.2 -1,-0.2 0.694 73.0 154.8 64.5 24.7 -22.9 4.6 1.5 176 179 A F - 0 0 15 -3,-0.4 -122,-0.3 -20,-0.0 -1,-0.2 -0.761 33.7-148.6 -85.9 129.3 -21.4 1.9 3.7 177 180 A D > - 0 0 65 -2,-0.5 3,-1.6 1,-0.1 -127,-0.1 -0.825 9.5-165.0-102.3 107.1 -23.5 1.5 6.9 178 181 A P G > S+ 0 0 0 0, 0.0 3,-2.0 0, 0.0 4,-0.2 0.646 79.8 81.1 -70.6 -9.3 -21.3 0.4 9.9 179 182 A R G > S+ 0 0 123 1,-0.3 3,-1.3 -130,-0.2 -26,-0.1 0.789 80.8 67.8 -59.9 -27.4 -24.5 -0.5 11.9 180 183 A G G < S+ 0 0 32 -3,-1.6 -27,-0.4 1,-0.2 -1,-0.3 0.446 94.9 56.6 -70.9 -0.2 -24.4 -3.7 9.9 181 184 A L G < S+ 0 0 0 -3,-2.0 -1,-0.2 -28,-0.1 -2,-0.2 0.381 86.0 101.2-108.8 2.2 -21.2 -4.8 11.8 182 185 A L < - 0 0 30 -3,-1.3 4,-0.1 -4,-0.2 -39,-0.0 -0.698 67.0-131.0 -93.8 139.9 -22.6 -4.6 15.3 183 186 A P - 0 0 14 0, 0.0 30,-0.1 0, 0.0 -1,-0.1 -0.187 32.4-101.3 -74.9-178.4 -23.7 -7.5 17.4 184 187 A E S S+ 0 0 179 2,-0.0 2,-0.4 1,-0.0 29,-0.0 0.846 102.6 56.6 -74.7 -37.8 -27.1 -7.5 19.2 185 188 A S - 0 0 32 1,-0.1 26,-0.3 2,-0.1 -1,-0.0 -0.820 58.9-161.3 -99.7 142.8 -25.8 -6.7 22.7 186 189 A L + 0 0 61 -2,-0.4 -141,-0.3 23,-0.1 -1,-0.1 0.138 44.5 138.1-104.8 21.2 -23.7 -3.5 23.6 187 190 A D + 0 0 66 -143,-0.1 23,-2.3 22,-0.1 24,-0.5 -0.413 35.0 175.0 -62.0 140.8 -22.5 -5.1 27.0 188 191 A Y E -M 209 0B 1 21,-0.3 68,-3.0 22,-0.1 2,-0.3 -0.956 38.6-132.7-148.4 160.9 -18.8 -4.2 27.2 189 192 A W E -MN 208 255B 10 19,-2.6 19,-2.8 -2,-0.3 2,-0.3 -0.861 30.2-167.2-106.0 156.5 -15.5 -4.1 29.1 190 193 A T E +MN 207 254B 8 64,-2.5 64,-2.4 -2,-0.3 17,-0.2 -0.998 16.5 153.3-146.6 145.9 -13.5 -0.9 29.3 191 194 A Y E -M 206 0B 5 15,-1.4 15,-2.6 -2,-0.3 2,-0.4 -0.969 46.0 -95.0-161.3 160.3 -10.0 0.2 30.3 192 195 A P E +M 205 0B 53 0, 0.0 13,-0.2 0, 0.0 2,-0.2 -0.715 62.2 131.3 -83.6 131.4 -7.4 2.9 29.5 193 196 A G E -M 204 0B 0 11,-3.4 11,-1.7 -2,-0.4 2,-0.3 -0.524 41.7 -90.7-152.9-146.2 -4.8 2.0 26.8 194 197 A S - 0 0 0 8,-0.2 8,-0.2 9,-0.2 7,-0.1 -0.841 43.5 -75.5-137.6 169.9 -3.1 2.8 23.7 195 198 A L - 0 0 29 6,-2.2 -168,-0.5 -2,-0.3 9,-0.0 -0.483 41.6-139.6 -60.6 146.7 -3.0 2.6 19.9 196 199 A T S S+ 0 0 6 -2,-0.1 -1,-0.1 -170,-0.1 -170,-0.0 0.396 82.8 51.2 -98.6 2.5 -2.0 -1.0 19.0 197 200 A T S > S- 0 0 38 4,-0.1 3,-2.6 45,-0.0 4,-0.2 -0.939 104.4 -42.2-122.5 160.2 0.3 0.0 16.2 198 201 A P T 3 S+ 0 0 10 0, 0.0 -2,-0.1 0, 0.0 -180,-0.0 -0.274 124.1 43.9 -46.1 140.9 3.1 2.6 16.0 199 202 A P T 3 S- 0 0 64 0, 0.0 -179,-0.2 0, 0.0 -178,-0.0 -0.975 83.8-162.8 -77.9 8.0 3.1 5.3 17.2 200 203 A L < - 0 0 0 -3,-2.6 -173,-0.1 1,-0.2 -4,-0.0 0.708 19.1-174.8 64.6 22.5 1.6 3.4 20.1 201 204 A L - 0 0 60 -4,-0.2 -6,-2.2 -7,-0.1 2,-1.8 -0.222 30.8-128.1 -63.8 142.9 0.3 6.6 21.8 202 205 A E S S+ 0 0 47 -8,-0.2 -8,-0.2 1,-0.2 -1,-0.1 -0.503 76.8 109.7 -90.5 66.8 -1.3 6.2 25.2 203 206 A C + 0 0 1 -2,-1.8 -65,-2.9 -67,-0.1 2,-0.5 0.177 46.1 107.3-126.5 10.9 -4.5 8.1 24.1 204 207 A V E -kM 138 193B 0 -11,-1.7 -11,-3.4 -3,-0.2 2,-0.7 -0.865 48.6-160.0-112.1 130.4 -7.3 5.5 24.0 205 208 A T E -kM 139 192B 27 -67,-2.6 -65,-1.8 -2,-0.5 2,-0.4 -0.930 33.0-147.4 -88.2 112.2 -10.3 4.6 26.1 206 209 A W E -kM 140 191B 4 -15,-2.6 -15,-1.4 -2,-0.7 2,-0.4 -0.729 19.4-174.6 -85.5 137.3 -10.9 1.0 25.0 207 210 A I E -kM 141 190B 0 -67,-2.5 -65,-2.9 -2,-0.4 2,-0.5 -0.970 7.9-171.4-129.9 112.3 -14.5 -0.3 24.9 208 211 A V E -kM 142 189B 1 -19,-2.8 -19,-2.6 -2,-0.4 2,-0.2 -0.935 18.2-134.4-112.2 119.5 -14.5 -4.1 24.0 209 212 A L E - M 0 188B 0 -67,-2.9 -65,-0.4 -2,-0.5 -21,-0.3 -0.458 4.1-146.0 -74.2 139.7 -17.9 -5.7 23.3 210 213 A K S S+ 0 0 81 -23,-2.3 -1,-0.1 -2,-0.2 -22,-0.1 0.854 81.1 72.3 -66.8 -37.3 -18.5 -9.0 25.0 211 214 A E S S- 0 0 69 -24,-0.5 -67,-0.2 -26,-0.3 2,-0.1 -0.732 75.7-147.4 -88.8 121.3 -20.7 -10.5 22.2 212 215 A P - 0 0 26 0, 0.0 2,-0.3 0, 0.0 -67,-0.2 -0.426 11.5-125.8 -76.8 160.7 -18.7 -11.4 19.0 213 216 A I E -l 145 0B 3 -69,-2.9 -67,-2.5 -30,-0.1 2,-0.4 -0.769 23.2-125.7 -95.6 154.0 -20.1 -11.2 15.5 214 217 A S E +l 146 0B 34 -2,-0.3 2,-0.3 -69,-0.2 -67,-0.2 -0.869 28.3 178.3 -98.4 133.5 -20.0 -14.2 13.2 215 218 A V E -l 147 0B 3 -69,-2.5 -67,-3.1 -2,-0.4 -65,-0.3 -0.899 30.5-104.8-122.9 158.7 -18.5 -14.1 9.8 216 219 A S > - 0 0 11 -2,-0.3 4,-2.3 -69,-0.2 5,-0.3 -0.424 22.6-116.3 -83.4 164.2 -18.1 -16.9 7.3 217 220 A S H > S+ 0 0 49 -69,-0.5 4,-2.7 1,-0.2 5,-0.2 0.952 118.7 54.3 -56.8 -44.6 -15.0 -18.8 6.4 218 221 A E H > S+ 0 0 112 1,-0.2 4,-1.4 2,-0.2 -1,-0.2 0.886 106.8 51.2 -61.9 -38.2 -15.3 -17.4 2.9 219 222 A Q H > S+ 0 0 1 2,-0.2 4,-1.2 1,-0.2 3,-0.4 0.958 113.4 42.6 -62.5 -48.8 -15.4 -13.8 4.2 220 223 A V H X S+ 0 0 2 -4,-2.3 4,-1.9 1,-0.2 -2,-0.2 0.878 107.9 61.5 -69.4 -31.6 -12.3 -14.1 6.4 221 224 A L H < S+ 0 0 87 -4,-2.7 -1,-0.2 -5,-0.3 4,-0.2 0.886 100.9 55.0 -59.3 -33.2 -10.5 -16.0 3.5 222 225 A K H >< S+ 0 0 82 -4,-1.4 3,-1.2 -3,-0.4 4,-0.4 0.862 103.1 54.0 -72.5 -32.0 -10.9 -12.9 1.4 223 226 A F H >< S+ 0 0 1 -4,-1.2 3,-1.6 1,-0.2 -1,-0.2 0.910 104.7 56.4 -59.6 -42.9 -9.2 -10.8 4.0 224 227 A R T 3< S+ 0 0 31 -4,-1.9 -1,-0.2 1,-0.3 -2,-0.2 0.498 95.5 65.9 -72.4 -4.3 -6.2 -13.2 3.9 225 228 A K T < S+ 0 0 145 -3,-1.2 -1,-0.3 -4,-0.2 -2,-0.2 0.535 80.6 100.1 -90.1 -12.1 -5.8 -12.6 0.1 226 229 A L < - 0 0 3 -3,-1.6 12,-2.8 -4,-0.4 2,-0.4 -0.213 69.5-130.0 -60.3 169.4 -4.8 -9.0 0.6 227 230 A N B -O 237 0C 6 -62,-2.7 10,-0.2 10,-0.3 -166,-0.2 -0.962 17.8-154.9-129.3 142.7 -1.1 -8.2 0.5 228 231 A F S S+ 0 0 30 8,-2.7 9,-0.1 -2,-0.4 -1,-0.1 0.737 82.0 77.4 -77.3 -28.1 1.3 -6.2 2.7 229 232 A N S S- 0 0 2 7,-0.6 -62,-2.3 1,-0.1 2,-0.1 -0.364 85.4-111.4 -77.0 161.1 3.5 -5.5 -0.3 230 233 A G > - 0 0 8 -64,-0.3 3,-1.4 1,-0.2 -62,-0.1 -0.448 50.6 -69.2 -85.9 170.3 2.9 -2.9 -3.1 231 234 A E T 3 S+ 0 0 165 -64,-0.5 -1,-0.2 1,-0.3 0, 0.0 -0.234 122.1 23.2 -58.5 141.3 2.0 -3.7 -6.7 232 235 A G T 3 S+ 0 0 87 1,-0.3 -1,-0.3 -3,-0.1 -2,-0.0 0.638 101.2 108.2 73.4 14.2 4.9 -5.3 -8.6 233 236 A E S < S- 0 0 96 -3,-1.4 -1,-0.3 1,-0.1 3,-0.1 -0.816 84.2 -81.2-115.7 159.7 6.6 -6.5 -5.4 234 237 A P - 0 0 112 0, 0.0 2,-0.3 0, 0.0 -5,-0.1 -0.343 59.1 -94.9 -66.2 147.6 6.8 -10.2 -4.3 235 238 A E + 0 0 113 -7,-0.1 2,-0.5 -8,-0.1 -8,-0.0 -0.421 42.8 175.3 -75.0 128.5 3.6 -11.3 -2.7 236 239 A E - 0 0 102 -2,-0.3 -8,-2.7 -3,-0.1 -7,-0.6 -0.971 33.6-129.4-125.6 103.7 3.5 -11.2 1.2 237 240 A L B -O 227 0C 82 -2,-0.5 2,-1.6 -10,-0.2 -10,-0.3 -0.383 17.5-119.2 -62.8 142.8 -0.0 -12.2 2.2 238 241 A M + 0 0 0 -12,-2.8 2,-0.3 -15,-0.2 -12,-0.3 -0.621 66.2 128.3 -83.0 91.6 -1.6 -9.7 4.7 239 242 A V + 0 0 28 -2,-1.6 -143,-0.2 1,-0.1 -142,-0.2 -0.969 51.7 28.4-142.2 154.8 -2.2 -12.1 7.7 240 243 A D + 0 0 42 -145,-0.9 2,-0.6 -2,-0.3 -144,-0.2 0.893 63.4 156.0 63.0 41.8 -1.3 -12.1 11.3 241 244 A N + 0 0 0 -146,-1.3 2,-0.4 -3,-0.1 -1,-0.2 -0.309 35.5 112.7 -96.6 50.8 -1.4 -8.3 11.6 242 245 A W - 0 0 41 -2,-0.6 -139,-0.1 -148,-0.1 -138,-0.1 -0.930 62.2-134.8-122.7 145.2 -2.2 -8.3 15.3 243 246 A R - 0 0 4 -2,-0.4 3,-0.1 -141,-0.1 -2,-0.0 -0.831 32.5-119.0 -92.4 136.8 -0.1 -7.2 18.3 244 247 A P - 0 0 56 0, 0.0 -140,-0.1 0, 0.0 -139,-0.1 -0.259 44.1 -70.8 -69.8 167.6 -0.1 -9.8 21.2 245 248 A A - 0 0 46 -141,-0.1 -216,-0.3 -216,-0.1 -218,-0.1 -0.282 52.5-149.9 -59.4 139.1 -1.5 -9.0 24.8 246 249 A Q - 0 0 45 -218,-2.7 -216,-0.4 -220,-0.2 -1,-0.1 -0.697 33.2 -71.4-109.1 164.6 0.7 -6.6 26.7 247 250 A P - 0 0 81 0, 0.0 -221,-0.4 0, 0.0 -1,-0.1 -0.234 33.3-146.9 -59.3 136.2 1.2 -6.3 30.5 248 251 A L + 0 0 64 1,-0.2 -219,-0.0 -223,-0.1 -2,-0.0 0.795 35.5 169.1 -70.6 -35.5 -1.8 -4.9 32.4 249 252 A K - 0 0 91 1,-0.2 2,-1.7 -224,-0.0 -1,-0.2 -0.196 65.5 -5.1 56.7-137.9 0.4 -3.1 35.0 250 253 A N S S+ 0 0 158 -226,-0.3 2,-0.3 2,-0.0 -1,-0.2 -0.540 106.1 116.3 -91.4 64.8 -1.4 -0.8 37.1 251 254 A R - 0 0 27 -2,-1.7 2,-0.5 -60,-0.0 -3,-0.0 -0.985 49.5-149.7-135.1 149.0 -4.9 -1.0 35.4 252 255 A Q - 0 0 89 -2,-0.3 2,-0.5 -216,-0.0 -216,-0.1 -0.947 12.2-147.4-113.1 127.0 -8.4 -2.1 36.2 253 256 A I - 0 0 9 -2,-0.5 -216,-2.1 -218,-0.2 2,-0.4 -0.836 19.1-156.0 -90.4 126.7 -10.8 -3.5 33.5 254 257 A K E -cN 37 190B 85 -64,-2.4 -64,-2.5 -2,-0.5 2,-0.4 -0.902 2.8-145.6-105.1 145.7 -14.4 -2.6 34.3 255 258 A A E -cN 38 189B 7 -218,-2.4 -216,-2.6 -2,-0.4 -66,-0.2 -0.869 9.1-153.7-108.9 138.9 -17.5 -4.5 33.1 256 259 A S S S+ 0 0 29 -68,-3.0 2,-0.3 -2,-0.4 -67,-0.1 0.491 81.0 54.0 -83.4 -3.7 -20.8 -2.8 32.2 257 260 A F 0 0 20 -69,-0.3 -2,-0.1 -70,-0.0 -218,-0.1 -0.876 360.0 360.0-132.4 158.7 -22.7 -6.1 33.0 258 261 A K 0 0 167 -2,-0.3 -2,-0.0 -220,-0.1 -221,-0.0 -0.363 360.0 360.0 71.7 360.0 -23.0 -8.6 35.8