==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=29-JUL-2012 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE/HYDROLASE INHIBITOR 31-JUL-11 3T7X . COMPND 2 MOLECULE: ENDOTHIAPEPSIN; . SOURCE 2 ORGANISM_SCIENTIFIC: CRYPHONECTRIA PARASITICA; . AUTHOR H.KOESTER,A.HEINE,G.KLEBE . 330 1 1 1 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13027.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 227 68.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 17 5.2 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 103 31.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 44 13.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 36 10.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 16 4.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 4 4 3 4 1 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 1 0 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A S 0 0 60 0, 0.0 152,-2.3 0, 0.0 153,-0.3 0.000 360.0 360.0 360.0 164.1 22.6 -13.3 11.3 2 2 A T - 0 0 58 150,-0.2 2,-0.3 96,-0.1 170,-0.2 -0.948 360.0-157.5-143.6 166.5 19.7 -12.8 8.9 3 3 A G E -A 171 0A 2 168,-2.1 168,-3.0 -2,-0.3 2,-0.3 -0.985 4.2-172.2-142.4 155.8 16.0 -13.3 8.8 4 4 A S E +A 170 0A 60 93,-2.0 2,-0.4 -2,-0.3 166,-0.2 -0.940 10.0 172.4-149.6 122.2 13.5 -13.8 6.0 5 5 A A E -A 169 0A 7 164,-2.7 164,-2.8 -2,-0.3 2,-0.3 -0.988 30.3-120.1-135.0 144.3 9.7 -13.9 6.3 6 6 A T E -A 168 0A 77 -2,-0.4 2,-0.4 162,-0.2 162,-0.3 -0.621 22.9-153.8 -79.9 137.7 6.8 -14.0 3.8 7 7 A T E -A 167 0A 0 160,-2.1 160,-2.8 -2,-0.3 155,-0.2 -0.942 11.2-162.6-115.2 136.9 4.3 -11.1 4.0 8 8 A T E -F 18 0B 60 10,-2.7 10,-2.7 -2,-0.4 153,-0.0 -0.952 23.0-111.7-127.7 133.5 0.8 -11.7 2.8 9 9 A P E -F 17 0B 20 0, 0.0 8,-0.3 0, 0.0 3,-0.0 -0.359 21.8-139.3 -60.5 142.8 -2.0 -9.3 1.7 10 10 A I S S+ 0 0 33 6,-2.6 2,-0.3 -2,-0.0 7,-0.1 0.671 77.9 1.2 -78.2 -15.8 -4.9 -9.4 4.2 11 11 A D S > S- 0 0 62 5,-0.4 3,-1.5 110,-0.0 5,-0.1 -0.903 89.9 -78.9-159.5-178.4 -7.6 -9.2 1.5 12 12 A S T 3 S+ 0 0 102 1,-0.3 -2,-0.0 -2,-0.3 0, 0.0 0.565 122.9 53.3 -72.5 -9.4 -8.1 -9.1 -2.3 13 13 A L T 3 S- 0 0 53 267,-0.1 -1,-0.3 3,-0.0 268,-0.0 0.382 107.6-118.1-103.0 -1.2 -7.3 -5.3 -2.4 14 14 A D < + 0 0 1 -3,-1.5 -2,-0.1 2,-0.1 3,-0.1 0.915 53.2 162.5 60.7 44.1 -3.9 -5.5 -0.7 15 15 A D - 0 0 54 1,-0.2 2,-0.3 292,-0.0 292,-0.1 0.817 67.7 -19.8 -66.3 -27.6 -5.3 -3.2 2.1 16 16 A A - 0 0 11 -5,-0.1 -6,-2.6 207,-0.1 -5,-0.4 -0.952 66.5-120.3-166.2 171.3 -2.5 -4.2 4.3 17 17 A Y E -F 9 0B 4 -2,-0.3 17,-0.4 -8,-0.3 2,-0.4 -0.969 18.0-155.4-126.1 139.6 0.1 -7.0 4.6 18 18 A I E -F 8 0B 25 -10,-2.7 -10,-2.7 -2,-0.4 15,-0.2 -0.927 5.2-168.6-118.9 145.6 0.7 -9.4 7.5 19 19 A T E -G 32 0C 0 13,-2.3 13,-2.6 -2,-0.4 2,-0.2 -0.992 28.0-114.6-132.9 130.2 3.9 -11.2 8.5 20 20 A P E -G 31 0C 48 0, 0.0 77,-0.4 0, 0.0 2,-0.4 -0.491 33.5-172.9 -72.0 138.8 4.1 -14.1 11.1 21 21 A V E -G 30 0C 0 9,-2.5 9,-2.5 -2,-0.2 2,-0.5 -0.998 17.8-138.7-134.5 130.1 6.1 -13.2 14.2 22 22 A Q E -GH 29 95C 58 73,-2.6 73,-2.7 -2,-0.4 2,-0.4 -0.808 24.5-177.6 -91.5 125.5 7.1 -15.6 17.0 23 23 A I E > -GH 28 94C 0 5,-2.4 5,-2.0 -2,-0.5 71,-0.2 -0.986 40.9 -10.7-126.4 130.0 6.8 -14.2 20.5 24 24 A G T 5S- 0 0 9 69,-2.9 4,-0.1 -2,-0.4 40,-0.1 -0.134 88.6 -40.5 87.7-178.7 7.7 -15.9 23.8 25 25 A T T 5S+ 0 0 55 1,-0.2 40,-2.7 2,-0.1 41,-0.3 -0.978 130.9 27.0-138.5 118.6 8.6 -19.4 25.0 26 26 A P T 5S- 0 0 96 0, 0.0 -1,-0.2 0, 0.0 40,-0.1 0.675 121.5 -99.8 -62.4 162.9 7.1 -21.6 23.8 27 27 A A T 5 - 0 0 63 -2,-0.2 2,-0.5 -5,-0.1 -3,-0.2 -0.227 31.4-162.0 -59.3 137.9 6.5 -19.5 20.7 28 28 A Q E < -G 23 0C 33 -5,-2.0 -5,-2.4 -4,-0.1 2,-0.6 -0.992 17.0-146.5-114.6 117.4 3.1 -17.8 20.2 29 29 A T E +G 22 0C 66 -2,-0.5 2,-0.3 -7,-0.2 -7,-0.2 -0.787 21.5 175.7 -93.8 121.6 2.8 -16.8 16.5 30 30 A L E -G 21 0C 0 -9,-2.5 -9,-2.5 -2,-0.6 2,-0.8 -0.920 31.1-125.0-118.9 149.8 0.9 -13.6 15.7 31 31 A N E -G 20 0C 57 -2,-0.3 92,-2.8 -11,-0.2 93,-0.4 -0.843 37.0-171.0 -98.4 109.3 0.4 -12.0 12.3 32 32 A L E -G 19 0C 0 -13,-2.6 -13,-2.3 -2,-0.8 2,-0.8 -0.722 27.5-123.8-108.2 150.7 1.7 -8.4 12.5 33 33 A D E -i 125 0C 17 91,-2.5 93,-2.1 -2,-0.3 2,-0.5 -0.829 28.4-140.4 -90.0 106.4 1.5 -5.5 10.2 34 34 A F E -i 126 0C 1 -2,-0.8 2,-0.5 -17,-0.4 93,-0.2 -0.600 23.9-169.6 -71.5 122.1 5.1 -4.4 9.6 35 35 A D E > -i 127 0C 9 91,-2.6 93,-2.8 -2,-0.5 3,-1.5 -0.889 25.9-175.3-128.5 100.9 5.0 -0.6 9.6 36 36 A T T 3 S+ 0 0 1 -2,-0.5 159,-0.5 1,-0.3 94,-0.2 0.486 86.4 65.3 -74.4 0.6 8.0 1.5 8.5 37 37 A G T 3 S+ 0 0 12 92,-0.1 2,-0.3 157,-0.1 -1,-0.3 0.316 104.2 39.5-101.8 6.5 6.0 4.6 9.6 38 38 A S < - 0 0 6 -3,-1.5 91,-2.7 88,-0.1 90,-0.7 -0.927 62.6-143.9-148.2 175.3 5.8 3.8 13.3 39 39 A S + 0 0 2 94,-0.3 2,-0.4 -2,-0.3 95,-0.1 0.099 61.6 98.5-136.7 22.6 8.1 2.5 16.0 40 40 A D - 0 0 0 94,-0.1 87,-0.9 -5,-0.1 2,-0.7 -0.929 53.1-152.3-114.7 135.5 6.0 0.4 18.4 41 41 A L E +J 126 0C 6 -2,-0.4 66,-2.9 64,-0.3 2,-0.3 -0.940 35.6 164.6-101.1 104.8 5.7 -3.4 18.4 42 42 A W E -Jk 125 107C 0 83,-1.7 83,-1.7 -2,-0.7 2,-0.3 -0.944 15.7-168.2-127.7 151.6 2.3 -3.9 20.0 43 43 A V E -Jk 124 108C 0 64,-2.4 66,-2.7 -2,-0.3 81,-0.3 -0.965 31.7-105.7-137.9 146.2 -0.1 -6.9 20.1 44 44 A F + 0 0 0 79,-2.6 15,-2.4 -2,-0.3 2,-0.3 -0.481 57.1 176.4 -56.0 142.8 -3.6 -8.0 20.9 45 45 A S B > -o 59 0D 2 64,-0.4 3,-1.7 13,-0.3 15,-0.2 -0.887 50.9 -89.3-148.5 174.3 -3.2 -9.8 24.2 46 46 A S T 3 S+ 0 0 59 13,-2.2 14,-0.1 -2,-0.3 4,-0.1 0.614 124.8 58.5 -63.3 -11.8 -4.9 -11.6 27.1 47 47 A E T 3 S+ 0 0 49 12,-0.3 -1,-0.3 62,-0.2 2,-0.2 0.504 78.6 113.8 -94.5 -9.1 -5.1 -8.1 28.6 48 48 A T S < S- 0 0 10 -3,-1.7 63,-0.2 1,-0.1 62,-0.2 -0.480 85.8 -93.7 -71.5 131.6 -7.1 -6.5 25.8 49 49 A T > - 0 0 59 61,-2.4 3,-2.3 -2,-0.2 4,-0.3 -0.174 38.0-130.1 -40.9 121.9 -10.6 -5.4 26.7 50 50 A A G > S+ 0 0 86 1,-0.3 3,-1.7 2,-0.2 -1,-0.1 0.829 104.1 55.0 -53.4 -42.5 -12.7 -8.5 25.8 51 51 A S G 3 S+ 0 0 102 1,-0.3 -1,-0.3 3,-0.0 -2,-0.1 0.606 103.6 58.4 -69.1 -11.2 -15.3 -6.5 23.8 52 52 A E G < S+ 0 0 50 -3,-2.3 2,-0.5 -4,-0.0 -1,-0.3 0.384 89.4 84.0-100.0 1.5 -12.5 -5.1 21.7 53 53 A V < + 0 0 43 -3,-1.7 2,-0.1 -4,-0.3 64,-0.1 -0.929 47.5 165.1-105.5 125.7 -11.2 -8.5 20.5 54 54 A D S S- 0 0 109 -2,-0.5 -3,-0.0 63,-0.2 -4,-0.0 -0.593 74.6 -34.8-142.0 75.4 -13.0 -10.0 17.5 55 55 A G S S+ 0 0 64 1,-0.3 -2,-0.1 -2,-0.1 65,-0.0 0.276 93.5 133.4 99.4 -11.0 -11.1 -12.9 16.0 56 56 A Q - 0 0 13 61,-0.1 2,-0.4 66,-0.1 -1,-0.3 -0.330 60.7-113.7 -67.0 152.2 -7.5 -11.8 16.5 57 57 A T - 0 0 68 63,-0.2 2,-0.3 -26,-0.1 -13,-0.3 -0.753 38.6-145.0 -81.8 135.6 -4.9 -14.1 17.8 58 58 A I - 0 0 62 -2,-0.4 2,-0.5 -15,-0.1 -13,-0.3 -0.769 9.4-129.5-108.9 149.2 -3.7 -12.9 21.2 59 59 A Y B -o 45 0D 0 -15,-2.4 -13,-2.2 -2,-0.3 -12,-0.3 -0.827 18.7-163.6 -87.3 129.5 -0.4 -12.9 23.1 60 60 A T > - 0 0 39 -2,-0.5 3,-1.8 -15,-0.2 4,-0.2 -0.879 4.8-172.0-115.8 95.4 -0.7 -14.3 26.6 61 61 A P G > S+ 0 0 7 0, 0.0 3,-2.0 0, 0.0 6,-0.3 0.828 80.8 66.6 -61.6 -28.7 2.4 -13.3 28.5 62 62 A S G 3 S+ 0 0 116 1,-0.3 -2,-0.0 3,-0.0 5,-0.0 0.718 99.7 53.3 -64.6 -17.5 1.6 -15.5 31.5 63 63 A K G < S+ 0 0 57 -3,-1.8 2,-0.6 -37,-0.0 -1,-0.3 0.408 92.4 86.8 -95.5 0.1 2.1 -18.5 29.2 64 64 A S X - 0 0 8 -3,-2.0 3,-1.2 -4,-0.2 -40,-0.1 -0.905 61.7-159.8-104.9 119.9 5.6 -17.4 28.2 65 65 A T T 3 S+ 0 0 121 -40,-2.7 -1,-0.1 -2,-0.6 -3,-0.0 0.658 94.5 49.6 -72.5 -14.0 8.4 -18.4 30.4 66 66 A T T 3 S+ 0 0 58 -41,-0.3 -1,-0.3 -40,-0.1 2,-0.2 0.441 84.6 111.2-101.8 -3.1 10.6 -15.7 29.0 67 67 A A < - 0 0 27 -3,-1.2 2,-0.4 -6,-0.3 25,-0.2 -0.537 42.8-176.8 -75.1 137.1 8.1 -12.8 29.4 68 68 A K E -L 91 0C 48 23,-2.1 23,-2.5 -2,-0.2 2,-0.2 -0.996 28.1-121.3-134.3 127.1 8.9 -10.2 32.0 69 69 A L E -L 90 0C 103 -2,-0.4 2,-1.0 21,-0.2 21,-0.3 -0.495 23.8-131.4 -63.9 130.3 6.7 -7.2 32.9 70 70 A L E > - 0 0 50 19,-3.0 3,-2.0 -2,-0.2 19,-0.4 -0.783 35.3-119.3 -86.0 105.0 8.5 -4.0 32.3 71 71 A S E 3 S- 0 0 114 -2,-1.0 3,-0.1 1,-0.3 -1,-0.0 -0.211 82.6 -6.3 -58.4 124.1 7.8 -2.3 35.6 72 72 A G E 3 S+ 0 0 62 1,-0.2 2,-0.3 17,-0.0 -1,-0.3 0.386 96.3 137.0 80.5 -2.0 5.8 1.0 35.3 73 73 A A E < + 0 0 7 -3,-2.0 16,-0.7 16,-0.2 2,-0.3 -0.612 23.3 168.2 -86.6 134.1 6.0 1.1 31.6 74 74 A T E -LM 88 137C 79 63,-2.7 63,-2.8 -2,-0.3 2,-0.3 -0.903 13.7-158.8-133.4 167.4 2.9 2.1 29.5 75 75 A W E +L 87 0C 5 12,-2.0 12,-2.1 -2,-0.3 2,-0.3 -0.979 10.2 178.1-145.8 156.6 2.3 3.0 25.9 76 76 A S E -L 86 0C 77 -2,-0.3 2,-0.4 10,-0.2 10,-0.2 -0.883 9.7-177.1-162.1 125.2 -0.3 4.9 23.8 77 77 A I E -L 85 0C 16 8,-2.7 8,-1.8 -2,-0.3 2,-0.4 -0.960 13.8-164.7-133.1 145.0 -0.2 5.5 20.1 78 78 A S E -L 84 0C 100 -2,-0.4 6,-0.2 6,-0.2 2,-0.2 -0.997 19.5-147.5-127.6 125.0 -2.4 7.4 17.7 79 79 A Y > - 0 0 35 4,-2.7 3,-2.2 -2,-0.4 -41,-0.0 -0.493 27.4-106.6 -93.0 162.0 -2.0 6.7 13.9 80 80 A G T 3 S+ 0 0 94 1,-0.3 -1,-0.1 -2,-0.2 -2,-0.0 0.673 117.1 59.8 -59.9 -19.9 -2.4 9.1 11.0 81 81 A D T 3 S- 0 0 125 2,-0.1 -1,-0.3 0, 0.0 3,-0.1 0.327 122.1-101.7 -92.8 6.6 -5.6 7.4 10.0 82 82 A G S < S+ 0 0 68 -3,-2.2 -2,-0.1 1,-0.3 2,-0.1 0.342 81.7 126.7 93.9 -7.1 -7.3 8.1 13.4 83 83 A S + 0 0 6 30,-0.1 -4,-2.7 31,-0.1 -1,-0.3 -0.346 33.6 177.8 -80.6 166.0 -6.9 4.7 14.9 84 84 A S E -L 78 0C 45 -6,-0.2 29,-2.5 -3,-0.1 2,-0.3 -0.989 16.1-177.8-162.9 162.1 -5.2 4.1 18.3 85 85 A S E +LN 77 112C 3 -8,-1.8 -8,-2.7 -2,-0.3 2,-0.3 -0.969 6.4 179.1-161.2 162.7 -4.2 1.6 20.9 86 86 A S E +LN 76 111C 29 25,-2.2 24,-3.0 -2,-0.3 25,-2.1 -0.986 17.1 115.9-162.2 162.8 -2.6 1.6 24.4 87 87 A G E -LN 75 109C 9 -12,-2.1 -12,-2.0 -2,-0.3 22,-0.2 -0.948 53.2 -49.0 171.0-147.6 -1.5 -0.7 27.2 88 88 A D E -LN 74 108C 24 20,-1.4 20,-1.9 -2,-0.3 2,-0.4 -0.461 47.6-115.1-114.3-173.8 1.4 -2.0 29.2 89 89 A V E + N 0 107C 0 -16,-0.7 -19,-3.0 -19,-0.4 2,-0.3 -0.981 22.0 179.4-138.2 135.1 4.8 -3.5 28.3 90 90 A Y E -LN 69 106C 34 16,-2.7 16,-3.3 -2,-0.4 2,-0.4 -0.843 23.0-135.2-116.3 159.7 6.6 -6.8 28.6 91 91 A T E +LN 68 105C 35 -23,-2.5 -23,-2.1 -2,-0.3 2,-0.3 -0.953 41.5 146.2-107.1 143.8 10.0 -7.8 27.4 92 92 A D E - N 0 104C 2 12,-1.9 12,-1.8 -2,-0.4 2,-0.4 -0.958 52.6 -75.2-160.8 172.7 10.2 -11.2 25.6 93 93 A T E - 0 0 30 -2,-0.3 -69,-2.9 9,-0.2 2,-0.4 -0.676 46.0-171.8 -80.5 130.4 11.9 -13.1 22.9 94 94 A V E -HN 23 101C 0 7,-2.7 7,-2.9 -2,-0.4 2,-0.4 -0.990 3.8-172.0-129.0 130.2 10.8 -12.2 19.4 95 95 A S E -HN 22 100C 22 -73,-2.7 -73,-2.6 -2,-0.4 2,-0.5 -0.977 7.1-172.0-126.0 138.8 11.7 -14.0 16.2 96 96 A V E > S- N 0 99C 0 3,-2.5 3,-2.2 -2,-0.4 -75,-0.1 -0.975 76.1 -27.7-129.0 113.8 11.0 -13.0 12.6 97 97 A G T 3 S- 0 0 29 -2,-0.5 -93,-2.0 -77,-0.4 74,-0.1 0.824 129.5 -41.8 53.6 38.2 11.8 -15.4 9.8 98 98 A G T 3 S+ 0 0 68 1,-0.3 2,-0.5 -95,-0.2 -1,-0.3 0.308 112.4 116.3 93.9 -9.3 14.6 -17.1 11.8 99 99 A L E < - N 0 96C 6 -3,-2.2 -3,-2.5 -98,-0.1 2,-0.4 -0.859 49.8-159.6 -95.7 124.2 16.1 -13.9 13.3 100 100 A T E - N 0 95C 76 -2,-0.5 2,-0.5 -5,-0.2 -5,-0.2 -0.882 15.4-173.6-115.0 132.9 15.8 -13.7 17.1 101 101 A V E - N 0 94C 10 -7,-2.9 -7,-2.7 -2,-0.4 3,-0.5 -0.991 13.6-152.8-118.1 125.8 15.9 -10.8 19.5 102 102 A T E S+ 0 0 110 -2,-0.5 -9,-0.2 -9,-0.2 -2,-0.0 -0.721 78.1 23.1 -92.0 149.2 15.9 -11.4 23.2 103 103 A G E S+ 0 0 45 -2,-0.3 2,-0.2 1,-0.2 -1,-0.2 0.731 80.8 165.4 70.4 22.9 14.5 -8.7 25.5 104 104 A Q E - N 0 92C 2 -12,-1.8 -12,-1.9 -3,-0.5 2,-0.5 -0.517 43.3-114.1 -68.8 135.7 12.4 -7.1 22.9 105 105 A A E - N 0 91C 2 37,-0.4 2,-0.6 -2,-0.2 -64,-0.3 -0.611 32.7-169.3 -71.1 119.2 9.8 -4.7 24.2 106 106 A V E - N 0 90C 0 -16,-3.3 -16,-2.7 -2,-0.5 2,-0.7 -0.964 12.4-147.0-112.9 112.4 6.4 -6.2 23.4 107 107 A E E -kN 42 89C 1 -66,-2.9 -64,-2.4 -2,-0.6 2,-0.5 -0.740 10.8-150.9 -89.8 112.3 3.6 -3.7 24.0 108 108 A S E -kN 43 88C 0 -20,-1.9 -20,-1.4 -2,-0.7 2,-0.3 -0.728 15.0-127.8 -88.9 123.4 0.5 -5.5 25.2 109 109 A A E + N 0 87C 0 -66,-2.7 -64,-0.4 -2,-0.5 -22,-0.3 -0.545 32.4 170.4 -76.1 130.6 -2.8 -3.8 24.3 110 110 A K E S+ 0 0 93 -24,-3.0 -61,-2.4 1,-0.3 2,-0.4 0.677 79.9 22.5 -96.1 -30.5 -5.3 -3.1 27.0 111 111 A K E + N 0 86C 131 -25,-2.1 -25,-2.2 -63,-0.2 -1,-0.3 -0.994 64.1 179.0-137.4 140.3 -7.4 -0.9 24.6 112 112 A V E - N 0 85C 8 -2,-0.4 -27,-0.2 -27,-0.2 2,-0.1 -0.978 30.3-111.6-135.1 152.1 -7.6 -0.8 20.8 113 113 A S >> - 0 0 25 -29,-2.5 4,-1.8 -2,-0.3 3,-1.2 -0.303 39.0 -94.9 -79.9 169.0 -9.8 1.5 18.6 114 114 A S H 3> S+ 0 0 78 1,-0.3 4,-2.6 2,-0.2 5,-0.2 0.807 119.4 59.4 -56.7 -37.5 -12.7 0.2 16.5 115 115 A S H 34 S+ 0 0 51 1,-0.2 4,-0.4 2,-0.2 -1,-0.3 0.856 107.8 46.8 -64.8 -32.6 -10.8 -0.2 13.3 116 116 A F H X4 S+ 0 0 23 -3,-1.2 3,-1.2 -32,-0.2 6,-0.2 0.940 112.6 48.9 -70.6 -47.4 -8.4 -2.6 14.9 117 117 A T H 3< S+ 0 0 20 -4,-1.8 -63,-0.2 1,-0.3 -2,-0.2 0.896 109.3 53.8 -54.4 -41.6 -11.2 -4.6 16.5 118 118 A E T 3< S+ 0 0 145 -4,-2.6 2,-0.8 -5,-0.2 -1,-0.3 0.580 96.3 72.9 -76.7 -10.7 -13.0 -4.8 13.2 119 119 A D X + 0 0 40 -3,-1.2 3,-1.1 -4,-0.4 -1,-0.2 -0.834 57.7 179.9-108.1 96.5 -10.0 -6.2 11.4 120 120 A S T 3 S+ 0 0 63 -2,-0.8 -63,-0.2 1,-0.2 -1,-0.1 0.648 73.7 65.2 -70.1 -15.2 -9.7 -9.8 12.5 121 121 A T T 3 S+ 0 0 44 -65,-0.1 2,-0.6 1,-0.1 -1,-0.2 0.603 87.2 72.4 -87.1 -14.4 -6.6 -10.4 10.3 122 122 A I < - 0 0 11 -3,-1.1 -90,-0.2 -6,-0.2 -3,-0.1 -0.913 51.5-178.5-110.1 115.4 -4.2 -8.1 12.0 123 123 A D - 0 0 3 -92,-2.8 -79,-2.6 -2,-0.6 2,-0.3 0.399 65.1 -53.8 -92.0 0.5 -2.9 -9.2 15.5 124 124 A G E - J 0 43C 0 -93,-0.4 -91,-2.5 -81,-0.3 2,-0.3 -0.930 62.0 -78.7 151.8-174.2 -0.8 -6.1 16.0 125 125 A L E -iJ 33 42C 7 -83,-1.7 -83,-1.7 -2,-0.3 2,-0.5 -0.909 16.0-155.0-121.9 149.4 2.0 -3.9 14.5 126 126 A L E -iJ 34 41C 0 -93,-2.1 -91,-2.6 -2,-0.3 -85,-0.3 -0.943 25.7-144.6-121.5 105.4 5.7 -4.2 14.3 127 127 A G E +i 35 0C 2 -87,-0.9 17,-0.5 -2,-0.5 18,-0.4 -0.502 24.6 175.0 -77.2 138.8 7.2 -0.8 13.9 128 128 A L + 0 0 2 -93,-2.8 -92,-0.2 -90,-0.7 -89,-0.2 0.143 47.4 101.9-130.3 14.3 10.2 -0.2 11.7 129 129 A A S S- 0 0 4 -91,-2.7 65,-0.2 -94,-0.6 14,-0.1 -0.139 90.2 -56.5 -79.3-170.5 10.6 3.6 11.8 130 130 A F > - 0 0 40 63,-2.2 3,-2.2 -94,-0.2 4,-0.2 -0.451 45.5-121.9 -78.9 145.5 13.3 5.2 14.0 131 131 A S G > S+ 0 0 16 1,-0.3 3,-2.0 2,-0.2 -1,-0.1 0.692 102.8 80.8 -62.7 -17.0 13.2 4.4 17.7 132 132 A T G 3 S+ 0 0 97 1,-0.3 -1,-0.3 8,-0.1 10,-0.0 0.720 90.6 55.1 -58.8 -20.7 12.8 8.1 18.5 133 133 A L G < S+ 0 0 61 -3,-2.2 -94,-0.3 60,-0.2 -1,-0.3 0.505 76.8 123.9 -88.9 -5.5 9.1 7.7 17.7 134 134 A N < - 0 0 8 -3,-2.0 -94,-0.1 7,-0.2 6,-0.0 -0.336 51.7-152.2 -62.8 136.5 8.6 4.8 20.2 135 135 A T + 0 0 41 5,-0.1 -59,-0.2 2,-0.0 -1,-0.1 0.438 48.2 127.5 -93.3 0.0 5.7 5.7 22.6 136 136 A V - 0 0 7 -61,-0.1 -61,-0.2 5,-0.1 -63,-0.1 -0.368 53.9-122.6 -64.9 134.8 6.7 3.7 25.7 137 137 A S B S+M 74 0C 66 -63,-2.8 -63,-2.7 1,-0.2 -2,-0.0 -0.971 74.8 4.8-131.0 144.3 6.9 5.9 28.9 138 138 A P S S+ 0 0 103 0, 0.0 2,-0.6 0, 0.0 -1,-0.2 -0.996 135.8 33.3 -89.8 -0.6 8.7 6.7 31.0 139 139 A T S S- 0 0 89 -4,-0.0 -2,-0.1 0, 0.0 -3,-0.0 -0.936 83.1-134.5-119.9 107.9 11.6 4.8 29.3 140 140 A Q - 0 0 100 -2,-0.6 2,-0.2 1,-0.1 -3,-0.1 -0.280 23.3-142.3 -60.5 143.3 11.4 4.7 25.5 141 141 A Q - 0 0 37 -10,-0.1 2,-0.2 -102,-0.1 -7,-0.2 -0.704 9.8-110.8-111.2 160.7 12.1 1.3 23.9 142 142 A K - 0 0 25 -2,-0.2 -37,-0.4 1,-0.1 -12,-0.1 -0.586 29.3-113.4 -90.0 148.4 13.9 0.2 20.8 143 143 A T > - 0 0 8 -2,-0.2 4,-2.4 -14,-0.1 5,-0.2 -0.292 32.2-105.7 -68.7 163.6 12.4 -1.3 17.6 144 144 A F H > S+ 0 0 1 -17,-0.5 4,-2.1 1,-0.2 5,-0.2 0.905 123.5 48.4 -54.9 -45.0 13.0 -4.9 16.6 145 145 A F H > S+ 0 0 17 -18,-0.4 4,-2.0 2,-0.2 -1,-0.2 0.922 109.0 52.5 -64.3 -43.2 15.3 -3.7 13.9 146 146 A D H 4 S+ 0 0 86 1,-0.2 4,-0.4 2,-0.2 -1,-0.2 0.876 113.0 45.3 -59.0 -41.3 17.2 -1.4 16.2 147 147 A N H < S+ 0 0 68 -4,-2.4 -1,-0.2 1,-0.2 4,-0.2 0.842 118.7 41.5 -70.3 -35.7 17.7 -4.4 18.6 148 148 A A H >X S+ 0 0 3 -4,-2.1 3,-1.4 -5,-0.2 4,-1.0 0.704 90.3 92.0 -83.2 -21.9 18.8 -6.8 15.9 149 149 A K G >< S+ 0 0 25 -4,-2.0 3,-0.8 1,-0.3 -1,-0.2 0.797 81.8 50.5 -51.1 -48.3 21.0 -4.4 13.9 150 150 A A G 34 S+ 0 0 101 -4,-0.4 -1,-0.3 1,-0.3 -2,-0.1 0.806 112.2 49.1 -62.3 -31.1 24.4 -5.1 15.5 151 151 A S G <4 S+ 0 0 80 -3,-1.4 -1,-0.3 -4,-0.2 -2,-0.2 0.655 90.8 103.2 -82.4 -18.6 23.9 -8.9 15.0 152 152 A L S << S- 0 0 14 -4,-1.0 -150,-0.2 -3,-0.8 20,-0.1 -0.307 78.7-125.8 -68.7 149.2 22.9 -8.6 11.4 153 153 A D S S+ 0 0 121 -152,-2.3 -1,-0.1 1,-0.2 20,-0.1 0.881 103.7 8.1 -57.3 -38.2 25.3 -9.5 8.5 154 154 A S S S- 0 0 48 18,-0.4 2,-2.4 -153,-0.3 -1,-0.2 -0.983 87.3-113.4-142.7 141.5 24.5 -6.0 7.2 155 155 A P S S+ 0 0 50 0, 0.0 164,-2.2 0, 0.0 2,-0.3 -0.333 80.5 99.0 -79.8 64.6 22.5 -3.3 9.0 156 156 A V E -B 318 0A 4 -2,-2.4 16,-3.1 162,-0.2 2,-0.3 -0.929 50.1-161.4-141.5 156.5 19.5 -3.4 6.6 157 157 A F E -BC 317 171A 0 160,-1.9 160,-3.1 -2,-0.3 2,-0.4 -0.966 16.2-149.2-134.7 158.1 16.1 -4.7 6.0 158 158 A T E -BC 316 170A 0 12,-2.6 12,-1.6 -2,-0.3 2,-0.5 -0.965 4.1-151.0-128.9 145.3 14.2 -4.9 2.7 159 159 A A E +BC 315 169A 1 156,-2.4 156,-2.4 -2,-0.4 2,-0.3 -0.971 15.9 172.3-114.7 125.0 10.6 -4.8 1.7 160 160 A D E - C 0 168A 31 8,-2.1 8,-2.0 -2,-0.5 2,-0.2 -0.724 16.4-173.8-131.6 78.1 9.4 -6.7 -1.3 161 161 A L - 0 0 1 152,-0.4 2,-0.2 -2,-0.3 152,-0.1 -0.544 15.0-133.9 -80.8 139.1 5.6 -6.3 -1.3 162 162 A G - 0 0 11 3,-0.5 2,-0.7 -155,-0.2 3,-0.2 -0.552 10.7-123.1 -89.7 154.1 3.5 -8.2 -3.8 163 163 A Y S S- 0 0 71 1,-0.2 -149,-0.1 -2,-0.2 114,-0.0 -0.887 96.8 -23.6 -93.3 115.0 0.6 -7.0 -5.9 164 164 A H S S+ 0 0 92 -2,-0.7 -1,-0.2 1,-0.2 -152,-0.0 0.831 134.6 77.3 49.9 37.4 -2.3 -9.3 -5.1 165 165 A A S S- 0 0 40 -3,-0.2 -3,-0.5 -158,-0.0 -1,-0.2 -0.982 89.9 -81.4-163.9 159.4 0.3 -11.9 -4.0 166 166 A P + 0 0 84 0, 0.0 -158,-0.2 0, 0.0 2,-0.2 -0.219 44.7 178.9 -67.4 163.4 2.7 -12.7 -1.2 167 167 A G E -A 7 0A 8 -160,-2.8 -160,-2.1 -5,-0.1 2,-0.4 -0.656 20.0-100.4-145.4-160.4 6.1 -10.9 -0.8 168 168 A T E -AC 6 160A 38 -8,-2.0 -8,-2.1 -162,-0.3 2,-0.5 -0.996 8.7-159.3-144.6 137.9 9.0 -10.9 1.5 169 169 A Y E -AC 5 159A 2 -164,-2.8 -164,-2.7 -2,-0.4 2,-0.4 -0.989 24.0-171.0-108.2 122.8 10.7 -9.0 4.4 170 170 A N E -AC 4 158A 5 -12,-1.6 -12,-2.6 -2,-0.5 2,-0.5 -0.906 7.6-158.1-112.6 143.7 14.4 -9.7 4.7 171 171 A F E S+AC 3 157A 0 -168,-3.0 -168,-2.1 -2,-0.4 -14,-0.2 -0.986 70.9 6.6-120.3 126.9 16.7 -8.7 7.5 172 172 A G S S+ 0 0 1 -16,-3.1 -18,-0.4 -2,-0.5 2,-0.3 0.383 115.2 54.9 94.0 -2.0 20.4 -8.4 7.3 173 173 A F - 0 0 62 -170,-0.2 2,-0.6 -17,-0.2 -15,-0.1 -0.990 69.5-125.1-157.5 158.2 21.0 -9.1 3.6 174 174 A I - 0 0 50 -2,-0.3 2,-1.1 -3,-0.1 142,-0.0 -0.938 22.7-140.8-108.3 118.7 20.0 -8.0 0.1 175 175 A D > - 0 0 52 -2,-0.6 3,-1.9 1,-0.2 4,-0.1 -0.710 13.0-165.9 -80.4 102.4 18.6 -10.7 -2.1 176 176 A T T 3 S+ 0 0 100 -2,-1.1 3,-0.3 1,-0.3 -1,-0.2 0.557 84.2 60.6 -71.1 -7.2 20.2 -9.8 -5.5 177 177 A T T 3 S+ 0 0 117 1,-0.2 -1,-0.3 3,-0.0 -2,-0.1 0.473 89.1 74.2 -91.4 -2.6 17.8 -12.2 -7.3 178 178 A A S < S+ 0 0 21 -3,-1.9 2,-0.3 152,-0.1 -1,-0.2 0.427 97.9 36.1 -94.9 -1.0 14.7 -10.3 -6.1 179 179 A Y S S- 0 0 45 -3,-0.3 151,-0.3 151,-0.2 2,-0.3 -0.934 71.7-122.6-144.9 166.8 15.0 -7.2 -8.4 180 180 A T S S- 0 0 77 149,-2.3 149,-0.4 -2,-0.3 134,-0.1 -0.753 73.7 -3.8-108.5 160.6 16.0 -6.2 -11.9 181 181 A G S S- 0 0 73 -2,-0.3 2,-0.2 147,-0.1 -2,-0.1 -0.247 106.3 -36.2 60.2-145.5 18.7 -3.7 -12.8 182 182 A S - 0 0 88 145,-0.1 2,-0.5 0, 0.0 147,-0.4 -0.708 52.7-112.1-111.8 161.8 20.4 -1.8 -10.0 183 183 A I - 0 0 25 -2,-0.2 2,-0.6 145,-0.1 145,-0.2 -0.829 27.9-150.5 -91.0 126.5 19.3 -0.4 -6.6 184 184 A T E -D 327 0A 30 143,-2.7 143,-2.3 -2,-0.5 2,-0.3 -0.899 11.6-151.2 -99.3 121.6 19.4 3.4 -6.6 185 185 A Y E -D 326 0A 105 -2,-0.6 2,-0.3 141,-0.2 141,-0.3 -0.690 13.6-173.5 -94.9 148.8 20.1 4.9 -3.1 186 186 A T E -D 325 0A 28 139,-2.7 139,-2.2 -2,-0.3 13,-0.1 -0.961 30.4 -89.0-143.3 151.5 18.8 8.2 -2.0 187 187 A A E -D 324 0A 75 -2,-0.3 11,-0.4 137,-0.2 2,-0.4 -0.250 35.6-152.9 -67.5 149.0 19.3 10.4 1.1 188 188 A V - 0 0 25 135,-0.8 2,-0.5 9,-0.1 9,-0.2 -0.956 6.5-152.5-122.0 137.7 17.1 10.0 4.2 189 189 A S B -P 196 0E 55 7,-2.5 7,-1.2 -2,-0.4 3,-0.3 -0.952 7.4-174.3-103.5 131.0 16.3 12.6 6.9 190 190 A T > + 0 0 63 -2,-0.5 3,-1.8 1,-0.2 -1,-0.1 0.254 53.9 110.3-103.2 11.1 15.5 11.1 10.3 191 191 A K T 3 S+ 0 0 90 1,-0.3 -1,-0.2 2,-0.1 -2,-0.0 0.788 85.7 37.1 -60.4 -32.3 14.5 14.4 11.8 192 192 A Q T 3 S- 0 0 100 -3,-0.3 -1,-0.3 2,-0.2 3,-0.1 0.309 118.8-107.8 -99.4 7.2 10.8 13.4 12.0 193 193 A G S < S+ 0 0 1 -3,-1.8 -63,-2.2 1,-0.3 -60,-0.2 0.480 85.0 109.8 81.2 4.5 11.6 9.8 12.9 194 194 A F S S- 0 0 46 -5,-0.2 2,-1.8 -65,-0.2 -1,-0.3 -0.597 86.6-101.5-106.0 166.5 10.5 8.5 9.5 195 195 A W + 0 0 3 -159,-0.5 23,-2.4 23,-0.4 2,-0.4 -0.654 60.9 177.3 -80.5 78.3 12.3 7.1 6.5 196 196 A E E +PQ 189 217E 13 -2,-1.8 -7,-2.5 -7,-1.2 2,-0.2 -0.765 7.0 154.2 -97.8 131.2 11.9 10.5 4.8 197 197 A W E - Q 0 216E 2 19,-2.9 19,-2.8 -2,-0.4 2,-0.5 -0.834 39.5-109.8-146.0 177.9 13.3 11.1 1.4 198 198 A T E - Q 0 215E 55 -11,-0.4 69,-0.4 -2,-0.2 17,-0.3 -0.943 21.4-149.3-126.5 110.4 12.9 13.3 -1.7 199 199 A S E - Q 0 214E 0 15,-2.9 15,-2.4 -2,-0.5 67,-0.2 -0.473 14.1-136.9 -70.3 149.9 11.6 11.9 -5.0 200 200 A T E - 0 0 45 65,-0.9 12,-1.5 13,-0.2 2,-0.3 0.444 61.5 -67.6 -92.3 -2.3 12.9 13.6 -8.1 201 201 A G E - Q 0 211E 0 64,-0.4 64,-2.4 10,-0.3 2,-0.3 -0.947 46.6-108.2 150.1-164.6 9.5 13.8 -9.9 202 202 A Y E -RQ 264 210E 33 8,-1.7 8,-3.4 -2,-0.3 2,-0.3 -0.982 6.9-153.9-155.9 163.4 6.8 11.9 -11.7 203 203 A A E -R 263 0E 6 60,-1.9 60,-2.6 -2,-0.3 2,-0.5 -0.981 16.6-137.5-138.1 155.0 5.0 11.0 -14.9 204 204 A V E > -R 262 0E 21 4,-0.3 3,-2.3 -2,-0.3 58,-0.2 -0.958 66.8 -47.0-112.4 122.0 1.5 9.9 -15.6 205 205 A G T 3 S- 0 0 21 56,-2.9 58,-0.1 -2,-0.5 54,-0.0 -0.296 122.1 -20.8 57.1-132.9 1.1 7.1 -18.1 206 206 A S T 3 S+ 0 0 134 -3,-0.0 -1,-0.3 56,-0.0 3,-0.1 0.268 108.9 124.8 -90.4 10.6 3.3 7.6 -21.2 207 207 A G S < S- 0 0 40 -3,-2.3 2,-0.1 1,-0.2 3,-0.0 -0.057 71.6 -77.2 -67.8 169.9 3.5 11.3 -20.5 208 208 A T - 0 0 134 1,-0.1 -4,-0.3 -5,-0.1 2,-0.3 -0.387 50.1-107.2 -69.3 144.6 6.6 13.4 -20.1 209 209 A F - 0 0 54 -6,-0.1 2,-0.6 -3,-0.1 -6,-0.2 -0.569 27.3-145.9 -74.5 130.6 8.5 13.2 -16.8 210 210 A K E -Q 202 0E 123 -8,-3.4 -8,-1.7 -2,-0.3 2,-0.7 -0.889 9.0-142.5 -99.5 116.0 8.1 16.3 -14.6 211 211 A S E +Q 201 0E 98 -2,-0.6 2,-0.3 -10,-0.2 -10,-0.3 -0.710 45.3 134.3 -80.6 117.0 11.3 17.0 -12.6 212 212 A T E - 0 0 58 -12,-1.5 2,-0.4 -2,-0.7 -2,-0.1 -0.946 56.3-108.9-164.1 138.5 10.2 18.3 -9.2 213 213 A S E - 0 0 99 -2,-0.3 2,-0.5 -13,-0.1 -13,-0.2 -0.612 31.5-176.6 -77.7 125.4 11.2 17.6 -5.6 214 214 A I E -Q 199 0E 7 -15,-2.4 -15,-2.9 -2,-0.4 2,-0.4 -0.920 10.6-157.2-124.7 104.2 8.6 15.6 -3.6 215 215 A D E +Q 198 0E 65 -2,-0.5 88,-0.7 -17,-0.3 2,-0.3 -0.639 34.1 133.8 -79.2 131.8 9.5 15.1 0.0 216 216 A G E -Qs 197 303E 0 -19,-2.8 -19,-2.9 -2,-0.4 2,-0.4 -0.958 47.8 -97.1-164.5-179.8 7.8 12.1 1.6 217 217 A I E -Qs 196 304E 6 86,-1.9 88,-2.9 -2,-0.3 2,-0.8 -0.882 22.3-128.2-115.7 143.3 8.1 9.0 3.7 218 218 A A E + s 0 305E 1 -23,-2.4 2,-0.5 -2,-0.4 -23,-0.4 -0.814 40.8 174.8 -85.0 109.4 8.4 5.3 2.8 219 219 A D > - 0 0 13 86,-2.1 3,-1.6 -2,-0.8 88,-0.3 -0.866 26.7-178.1-131.1 98.0 5.6 3.8 4.8 220 220 A T T 3 S+ 0 0 2 -2,-0.5 -203,-0.2 1,-0.3 -1,-0.1 0.699 85.1 63.5 -68.2 -18.1 4.7 0.1 4.6 221 221 A G T 3 S+ 0 0 26 -205,-0.1 2,-0.5 -188,-0.1 -1,-0.3 0.412 88.5 78.3 -87.6 0.7 1.9 0.6 7.1 222 222 A T < - 0 0 28 -3,-1.6 85,-3.0 1,-0.1 86,-0.2 -0.942 68.1-153.6-108.8 133.0 -0.1 3.0 4.8 223 223 A T + 0 0 37 -2,-0.5 85,-1.5 83,-0.2 -1,-0.1 0.919 67.8 47.3 -70.8 -46.7 -2.1 1.5 2.0 224 224 A L S S- 0 0 11 83,-0.2 82,-0.8 82,-0.1 2,-0.6 -0.310 81.4-106.2-101.3 174.8 -2.2 4.3 -0.6 225 225 A L E -tU 294 305E 0 68,-2.4 70,-2.7 80,-0.2 2,-0.6 -0.917 32.8-165.7-101.7 114.8 0.1 6.8 -2.3 226 226 A Y E +tU 295 304E 58 78,-2.6 78,-2.1 -2,-0.6 70,-0.2 -0.925 19.4 159.7-109.6 116.9 -0.5 10.3 -0.9 227 227 A L E -t 296 0E 0 68,-2.2 70,-2.4 -2,-0.6 71,-0.4 -0.795 46.2 -64.0-133.4 168.9 1.0 13.1 -3.0 228 228 A P >> - 0 0 35 0, 0.0 4,-2.3 0, 0.0 3,-0.6 -0.191 49.1-114.1 -59.7 150.1 0.6 16.9 -3.5 229 229 A A H 3> S+ 0 0 53 1,-0.3 4,-2.5 2,-0.2 5,-0.2 0.803 114.7 56.3 -54.8 -35.9 -2.8 18.0 -4.9 230 230 A T H 3> S+ 0 0 109 2,-0.2 4,-1.9 1,-0.2 -1,-0.3 0.918 110.3 44.4 -62.9 -43.3 -1.2 19.3 -8.1 231 231 A V H <> S+ 0 0 5 -3,-0.6 4,-1.8 2,-0.2 -2,-0.2 0.920 114.5 48.4 -67.1 -44.8 0.3 15.9 -8.8 232 232 A V H X S+ 0 0 0 -4,-2.3 4,-2.5 1,-0.2 5,-0.2 0.892 110.0 51.8 -66.9 -39.6 -2.8 13.9 -7.9 233 233 A S H X S+ 0 0 60 -4,-2.5 4,-2.0 -5,-0.2 -1,-0.2 0.916 107.9 53.0 -61.7 -42.6 -5.0 16.2 -10.1 234 234 A A H < S+ 0 0 36 -4,-1.9 4,-0.3 -5,-0.2 -1,-0.2 0.868 110.7 47.8 -61.3 -38.1 -2.7 15.6 -13.0 235 235 A Y H >< S+ 0 0 0 -4,-1.8 3,-1.9 1,-0.2 -2,-0.2 0.978 113.6 43.9 -65.5 -55.1 -3.0 11.9 -12.6 236 236 A W H >< S+ 0 0 5 -4,-2.5 3,-2.1 1,-0.3 6,-0.3 0.758 99.0 71.8 -69.2 -21.9 -6.8 11.7 -12.3 237 237 A A T 3< S+ 0 0 74 -4,-2.0 -1,-0.3 1,-0.3 -2,-0.2 0.704 92.5 60.4 -61.8 -19.6 -7.3 14.2 -15.2 238 238 A Q T < S+ 0 0 132 -3,-1.9 2,-0.6 -4,-0.3 -1,-0.3 0.386 91.6 78.3 -89.2 5.5 -6.1 11.3 -17.4 239 239 A V S X S- 0 0 9 -3,-2.1 3,-2.2 20,-0.1 -1,-0.1 -0.938 85.1-126.6-119.5 110.8 -9.1 9.1 -16.3 240 240 A S T 3 S+ 0 0 115 -2,-0.6 3,-0.1 1,-0.3 -2,-0.1 -0.328 93.3 10.8 -59.0 127.3 -12.4 9.8 -17.9 241 241 A G T 3 S+ 0 0 61 1,-0.3 -1,-0.3 12,-0.1 2,-0.1 0.357 90.0 141.6 88.1 -4.9 -15.1 10.4 -15.3 242 242 A A < + 0 0 25 -3,-2.2 2,-0.3 -6,-0.3 -1,-0.3 -0.429 22.5 167.3 -70.8 145.4 -12.7 10.6 -12.3 243 243 A K E -W 252 0F 51 9,-2.3 9,-2.7 -2,-0.1 2,-0.6 -0.991 41.2-108.6-154.1 152.9 -13.6 13.1 -9.7 244 244 A S E -W 251 0F 78 -2,-0.3 2,-0.6 7,-0.3 7,-0.3 -0.793 35.9-158.3 -84.7 122.0 -12.7 14.1 -6.1 245 245 A S E >> -W 250 0F 23 5,-2.8 4,-2.5 -2,-0.6 5,-1.8 -0.903 16.3-168.4-107.7 115.5 -15.6 13.2 -3.9 246 246 A S T 45S+ 0 0 122 -2,-0.6 -1,-0.2 1,-0.2 5,-0.0 0.872 91.7 53.2 -65.7 -35.6 -15.9 15.0 -0.6 247 247 A S T 45S+ 0 0 110 1,-0.2 -1,-0.2 2,-0.1 -2,-0.0 0.873 115.6 38.0 -69.6 -37.2 -18.6 12.6 0.5 248 248 A V T 45S- 0 0 56 2,-0.2 -2,-0.2 4,-0.0 -1,-0.2 0.837 113.0-117.5 -82.1 -33.4 -16.4 9.5 -0.2 249 249 A G T <5S+ 0 0 58 -4,-2.5 2,-0.3 1,-0.3 -3,-0.2 0.710 74.4 5.9 102.4 26.9 -13.2 11.1 1.0 250 250 A G E - X 0 289F 40 0, 0.0 3,-2.3 0, 0.0 35,-0.2 -0.401 34.3-134.6 -64.7 134.1 -15.6 4.6 -12.9 255 255 A a T 3 S+ 0 0 45 33,-2.8 34,-0.1 1,-0.3 26,-0.0 0.746 104.1 65.0 -62.4 -19.7 -15.0 0.9 -12.3 256 256 A S T 3 S+ 0 0 117 32,-0.3 -1,-0.3 2,-0.1 33,-0.1 0.517 83.0 110.1 -77.2 -6.8 -15.0 0.4 -16.1 257 257 A A < - 0 0 32 -3,-2.3 2,-0.6 -17,-0.1 -18,-0.1 -0.316 65.1-138.5 -71.0 151.5 -11.9 2.6 -16.5 258 258 A T - 0 0 134 -2,-0.0 -2,-0.1 0, 0.0 -1,-0.0 -0.968 30.4-138.6-103.3 117.9 -8.5 1.4 -17.5 259 259 A L - 0 0 15 -2,-0.6 16,-0.3 1,-0.1 17,-0.2 -0.541 7.9-126.1 -83.3 141.9 -6.0 3.3 -15.3 260 260 A P - 0 0 27 0, 0.0 18,-0.1 0, 0.0 -1,-0.1 -0.419 31.2-103.5 -75.3 157.1 -2.8 4.8 -16.5 261 261 A S - 0 0 31 -2,-0.1 -56,-2.9 13,-0.1 2,-0.4 -0.248 26.9-140.7 -68.5 167.1 0.5 3.9 -14.8 262 262 A F E -RV 204 273E 1 11,-2.2 11,-3.2 -58,-0.2 2,-0.4 -0.991 12.4-160.0-133.3 127.4 2.2 6.4 -12.5 263 263 A T E -RV 203 272E 15 -60,-2.6 -60,-1.9 -2,-0.4 2,-0.4 -0.886 4.8-168.6-108.2 135.1 6.0 6.8 -12.4 264 264 A F E -RV 202 271E 2 7,-2.4 7,-2.7 -2,-0.4 2,-0.3 -0.944 19.5-122.7-119.7 149.7 8.0 8.3 -9.6 265 265 A G E - V 0 270E 0 -64,-2.4 -65,-0.9 -2,-0.4 2,-0.4 -0.669 19.7-176.5 -92.0 140.0 11.7 9.3 -9.6 266 266 A V E > S- V 0 269E 0 3,-2.3 3,-2.5 -2,-0.3 -67,-0.1 -0.933 74.4 -55.6-127.5 103.7 14.4 8.1 -7.3 267 267 A G T 3 S- 0 0 29 -2,-0.4 -67,-0.2 -69,-0.4 -1,-0.1 -0.382 119.6 -24.6 53.9-132.8 17.5 10.1 -8.3 268 268 A S T 3 S+ 0 0 111 -3,-0.1 -1,-0.3 2,-0.1 2,-0.1 0.516 124.5 96.1 -82.8 -5.2 17.9 9.4 -12.1 269 269 A A E < -V 266 0E 25 -3,-2.5 -3,-2.3 58,-0.0 2,-0.4 -0.400 63.4-144.9 -85.0 163.4 16.0 6.1 -11.7 270 270 A R E -V 265 0E 95 -5,-0.2 2,-0.5 -2,-0.1 -5,-0.2 -0.994 6.3-160.2-134.1 132.0 12.3 5.6 -12.3 271 271 A I E -V 264 0E 3 -7,-2.7 -7,-2.4 -2,-0.4 2,-0.6 -0.964 15.2-151.3-110.9 125.9 9.8 3.3 -10.6 272 272 A V E -V 263 0E 77 -2,-0.5 -9,-0.2 40,-0.2 -2,-0.0 -0.867 4.1-159.8-104.3 119.3 6.7 2.5 -12.6 273 273 A I E -V 262 0E 0 -11,-3.2 -11,-2.2 -2,-0.6 5,-0.1 -0.872 25.6-128.4 -92.0 112.7 3.4 1.7 -10.7 274 274 A P > - 0 0 51 0, 0.0 3,-1.6 0, 0.0 4,-0.4 -0.286 19.2-114.6 -62.0 150.3 1.1 -0.1 -13.1 275 275 A G G > S+ 0 0 9 -16,-0.3 3,-2.0 1,-0.3 4,-0.2 0.854 112.8 62.7 -53.5 -38.8 -2.4 1.3 -13.5 276 276 A D G > S+ 0 0 99 1,-0.3 3,-1.3 2,-0.2 -1,-0.3 0.786 93.2 64.2 -59.5 -28.2 -4.0 -1.8 -11.9 277 277 A Y G < S+ 0 0 44 -3,-1.6 -1,-0.3 1,-0.2 -2,-0.2 0.673 96.9 58.6 -66.8 -17.1 -2.1 -1.2 -8.7 278 278 A I G < S+ 0 0 0 -3,-2.0 15,-2.1 -4,-0.4 2,-0.7 0.436 82.5 98.4 -96.0 -0.8 -4.1 2.1 -8.3 279 279 A D E < +Y 292 0F 62 -3,-1.3 13,-0.2 -4,-0.2 -24,-0.0 -0.794 40.3 173.4 -94.2 114.8 -7.5 0.4 -8.4 280 280 A F E - 0 0 13 11,-2.2 -1,-0.1 -2,-0.7 12,-0.1 0.180 42.7-125.8-107.8 18.9 -9.0 -0.1 -4.9 281 281 A G E - 0 0 7 10,-0.2 10,-2.7 9,-0.1 -1,-0.3 0.063 55.1 -5.1 75.2-178.3 -12.4 -1.4 -6.1 282 282 A P E -Y 290 0F 70 0, 0.0 8,-0.3 0, 0.0 6,-0.1 -0.120 55.8-134.3 -54.7 140.6 -16.0 -0.3 -5.4 283 283 A I S S+ 0 0 58 6,-2.8 2,-0.3 1,-0.2 7,-0.1 0.804 93.8 6.7 -65.8 -27.9 -16.5 2.4 -2.8 284 284 A S S > S- 0 0 81 5,-0.4 3,-2.5 0, 0.0 -1,-0.2 -0.966 109.1 -68.4-148.3 156.1 -19.3 0.3 -1.4 285 285 A T T 3 S+ 0 0 157 -2,-0.3 3,-0.1 1,-0.3 -2,-0.1 -0.183 119.9 6.9 -53.3 128.2 -20.4 -3.2 -2.2 286 286 A G T 3 S+ 0 0 80 1,-0.3 -1,-0.3 -4,-0.0 2,-0.1 0.365 94.7 135.3 83.8 -5.4 -22.0 -3.4 -5.6 287 287 A S < - 0 0 39 -3,-2.5 -1,-0.3 2,-0.1 0, 0.0 -0.447 52.5-147.2 -73.8 149.9 -21.1 0.2 -6.6 288 288 A S S S+ 0 0 98 -2,-0.1 -33,-2.8 -3,-0.1 2,-0.5 0.259 77.6 92.4 -96.9 7.9 -19.7 1.0 -10.0 289 289 A S E -X 254 0F 30 -35,-0.2 -6,-2.8 -5,-0.2 -5,-0.4 -0.922 66.2-157.7 -99.3 129.8 -17.7 3.9 -8.5 290 290 A a E -XY 253 282F 4 -37,-3.3 -37,-2.2 -2,-0.5 2,-0.4 -0.780 15.1-116.8-112.1 151.4 -14.2 2.8 -7.5 291 291 A F E -X 252 0F 47 -10,-2.7 -11,-2.2 -2,-0.3 -39,-0.2 -0.719 30.6-124.6 -91.3 132.8 -11.7 4.2 -5.0 292 292 A G E - Y 0 279F 0 -41,-2.4 -13,-0.2 -2,-0.4 -41,-0.1 -0.423 3.0-146.9 -76.8 147.9 -8.4 5.6 -6.3 293 293 A G S S+ 0 0 0 -15,-2.1 -68,-2.4 -2,-0.1 2,-0.5 0.474 86.7 65.9 -91.5 -5.0 -5.0 4.4 -5.0 294 294 A I E +t 225 0E 0 -16,-0.3 2,-0.3 -70,-0.2 -43,-0.2 -0.990 69.8 167.8-115.8 122.9 -3.4 7.8 -5.4 295 295 A Q E -t 226 0E 9 -70,-2.7 -68,-2.2 -2,-0.5 2,-0.2 -0.897 38.1 -87.8-135.4 161.2 -4.9 10.5 -3.2 296 296 A S E -t 227 0E 37 -2,-0.3 3,-0.3 -70,-0.2 -70,-0.0 -0.459 18.6-159.9 -71.8 139.5 -4.0 14.0 -2.1 297 297 A S >> + 0 0 9 -70,-2.4 3,-2.5 -2,-0.2 4,-1.2 0.380 62.1 112.6 -90.6 1.9 -1.8 14.6 0.9 298 298 A A T 34 S+ 0 0 79 -71,-0.4 -1,-0.2 1,-0.3 3,-0.1 0.794 79.9 41.2 -50.7 -37.5 -3.1 18.1 1.3 299 299 A G T 34 S+ 0 0 83 -3,-0.3 -1,-0.3 1,-0.2 -2,-0.1 0.054 109.8 61.6 -99.1 26.8 -4.9 17.4 4.6 300 300 A I T <4 S- 0 0 76 -3,-2.5 -2,-0.2 2,-0.0 -1,-0.2 0.680 90.6-132.3-120.3 -37.1 -2.1 15.2 6.1 301 301 A G S < S+ 0 0 77 -4,-1.2 2,-0.3 1,-0.1 -3,-0.1 0.347 81.8 55.7 93.5 -4.9 0.9 17.5 6.3 302 302 A I S S- 0 0 28 -5,-0.4 2,-0.3 -75,-0.0 -86,-0.1 -0.987 80.8-116.3-155.8 146.0 3.3 15.0 4.7 303 303 A N E -s 216 0E 22 -88,-0.7 -86,-1.9 -2,-0.3 2,-0.5 -0.649 31.4-154.1 -82.1 144.2 3.5 13.0 1.5 304 304 A I E -sU 217 226E 17 -78,-2.1 -78,-2.6 -2,-0.3 2,-1.5 -0.953 17.1-159.2-130.2 114.2 3.4 9.2 2.0 305 305 A F E +sU 218 225E 1 -88,-2.9 -86,-2.1 -2,-0.5 -80,-0.2 -0.725 38.3 170.9 -85.1 84.3 4.8 6.6 -0.3 306 306 A G >> - 0 0 0 -2,-1.5 4,-2.5 -82,-0.8 3,-1.2 0.011 51.6 -61.3 -84.5-163.4 2.6 3.8 1.0 307 307 A D H 3> S+ 0 0 2 -85,-3.0 4,-2.8 -88,-0.3 5,-0.2 0.802 126.9 65.3 -58.0 -36.0 2.1 0.3 -0.3 308 308 A V H 34 S+ 0 0 0 -85,-1.5 -1,-0.3 1,-0.2 4,-0.2 0.899 115.5 31.0 -52.5 -43.4 0.7 1.4 -3.7 309 309 A A H X4 S+ 0 0 0 -3,-1.2 3,-1.3 2,-0.1 -2,-0.2 0.908 119.8 51.3 -79.2 -47.3 4.2 2.8 -4.5 310 310 A L H >< S+ 0 0 1 -4,-2.5 3,-2.0 1,-0.3 -149,-0.3 0.843 100.4 61.8 -66.5 -32.7 6.4 0.5 -2.5 311 311 A K T 3< S+ 0 0 2 -4,-2.8 -1,-0.3 1,-0.3 -148,-0.1 0.670 95.7 62.9 -71.6 -13.4 4.9 -2.7 -3.9 312 312 A A T < S+ 0 0 11 -3,-1.3 18,-0.5 -5,-0.2 -1,-0.3 0.463 109.5 45.0 -80.6 -2.4 6.1 -1.6 -7.4 313 313 A A S < S- 0 0 0 -3,-2.0 2,-0.6 16,-0.2 -152,-0.4 -0.874 79.0-117.5-136.2 163.6 9.7 -1.7 -6.1 314 314 A F E - E 0 328A 0 14,-2.6 14,-2.1 -2,-0.3 2,-0.5 -0.952 45.3-158.1 -95.4 122.0 12.3 -3.7 -4.1 315 315 A V E -BE 159 327A 0 -156,-2.4 -156,-2.4 -2,-0.6 2,-0.6 -0.922 12.4-157.2-118.7 125.2 13.0 -1.3 -1.3 316 316 A V E -BE 158 326A 0 10,-2.7 10,-2.5 -2,-0.5 2,-0.9 -0.886 2.6-161.4-102.1 121.5 16.1 -1.2 0.9 317 317 A F E -BE 157 325A 0 -160,-3.1 -160,-1.9 -2,-0.6 2,-0.8 -0.880 17.0-161.4 -98.7 97.5 15.9 0.3 4.3 318 318 A N E -BE 156 324A 30 6,-2.3 6,-1.6 -2,-0.9 -162,-0.2 -0.766 13.4-175.0 -91.1 107.6 19.6 0.9 5.1 319 319 A G + 0 0 25 -164,-2.2 -163,-0.1 -2,-0.8 -1,-0.1 -0.058 33.2 138.0 -95.2 32.0 20.2 1.5 8.8 320 320 A A S S- 0 0 35 2,-0.3 -166,-0.0 4,-0.1 -2,-0.0 -0.088 79.8 -79.1 -60.2 173.6 23.9 2.3 8.5 321 321 A T S S+ 0 0 153 1,-0.3 -1,-0.1 2,-0.1 -2,-0.0 0.875 136.2 35.2 -47.0 -46.0 25.3 5.1 10.7 322 322 A T S S- 0 0 108 -135,-0.0 -2,-0.3 2,-0.0 -1,-0.3 -0.935 101.1-138.9-105.5 105.1 23.9 7.5 8.1 323 323 A P + 0 0 19 0, 0.0 -135,-0.8 0, 0.0 2,-0.3 -0.290 26.2 176.1 -65.6 149.1 20.6 5.8 6.9 324 324 A T E -DE 187 318A 32 -6,-1.6 -6,-2.3 -137,-0.2 2,-0.4 -0.904 23.5-127.5-139.9 172.8 19.6 5.8 3.3 325 325 A L E -DE 186 317A 0 -139,-2.2 -139,-2.7 -2,-0.3 2,-0.4 -0.971 17.9-160.3-123.4 137.8 16.8 4.3 1.2 326 326 A G E -DE 185 316A 0 -10,-2.5 -10,-2.7 -2,-0.4 2,-0.4 -0.946 4.5-169.7-119.0 142.0 17.3 2.1 -1.9 327 327 A F E +DE 184 315A 2 -143,-2.3 -143,-2.7 -2,-0.4 2,-0.3 -0.997 7.5 172.9-129.4 134.1 14.8 1.4 -4.7 328 328 A A E - E 0 314A 2 -14,-2.1 -14,-2.6 -2,-0.4 -145,-0.1 -0.971 32.1-117.2-129.1 150.9 15.0 -1.1 -7.6 329 329 A S 0 0 49 -149,-0.4 -149,-2.3 -147,-0.4 -16,-0.2 -0.370 360.0 360.0 -70.4 164.9 12.5 -2.2 -10.2 330 330 A K 0 0 104 -18,-0.5 -151,-0.2 -151,-0.3 -152,-0.1 -0.871 360.0 360.0-151.4 360.0 11.5 -5.8 -10.0