==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=8-JAN-2012 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 20-AUG-11 3TI7 . COMPND 2 MOLECULE: BASIC EXTRACELLULAR SUBTILISIN-LIKE PROTEASE BPRV . SOURCE 2 ORGANISM_SCIENTIFIC: DICHELOBACTER NODOSUS; . AUTHOR W.WONG,J.C.WHISSTOCK,C.J.PORTER . 340 1 2 2 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13065.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 217 63.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 36 10.6 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 19 5.6 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 24 7.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 35 10.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 71 20.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 5 1.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 0 1 0 0 1 2 1 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 4 1 2 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 6 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 2 A A 0 0 115 0, 0.0 2,-0.1 0, 0.0 7,-0.0 0.000 360.0 360.0 360.0 144.6 9.7 26.1 8.5 2 3 A P - 0 0 17 0, 0.0 5,-0.1 0, 0.0 121,-0.1 -0.406 360.0-127.2 -62.4 150.6 8.1 24.5 11.5 3 4 A N + 0 0 90 4,-0.1 120,-0.0 119,-0.1 113,-0.0 0.323 62.3 132.6 -87.4 5.9 10.0 25.4 14.8 4 5 A D >> - 0 0 2 1,-0.1 3,-1.8 116,-0.1 4,-0.5 -0.438 59.7-133.7 -63.4 124.5 10.5 21.8 15.9 5 6 A P T 34 S+ 0 0 62 0, 0.0 3,-0.2 0, 0.0 117,-0.2 0.732 102.4 42.7 -56.2 -28.8 14.2 21.4 17.0 6 7 A S T >4 S+ 0 0 24 115,-2.6 3,-1.4 1,-0.2 4,-0.4 0.413 85.1 93.4 -99.5 0.2 14.7 18.1 15.1 7 8 A Y G X4 S+ 0 0 21 -3,-1.8 3,-2.2 114,-0.4 6,-0.2 0.892 77.5 65.3 -56.1 -40.5 12.8 19.0 11.9 8 9 A R G 3< S+ 0 0 193 -4,-0.5 -1,-0.3 1,-0.3 -2,-0.1 0.725 99.8 52.5 -53.1 -25.5 16.1 20.1 10.4 9 10 A Q G < S+ 0 0 108 -3,-1.4 2,-1.6 1,-0.2 -1,-0.3 0.533 84.1 91.5 -87.5 -10.0 17.2 16.5 10.6 10 11 A Q X> + 0 0 0 -3,-2.2 3,-2.5 -4,-0.4 4,-0.7 -0.393 44.2 160.0 -88.3 61.5 14.1 15.3 8.7 11 12 A W H 3> + 0 0 44 -2,-1.6 4,-2.8 1,-0.3 3,-0.4 0.754 64.9 74.2 -47.5 -31.0 15.7 15.4 5.3 12 13 A H H 34 S+ 0 0 0 240,-0.3 7,-2.0 -3,-0.2 -1,-0.3 0.587 97.1 46.7 -68.6 -12.5 12.9 13.0 4.1 13 14 A Y H <4 S+ 0 0 0 -3,-2.5 8,-2.0 5,-0.2 9,-0.8 0.776 133.7 3.3 -90.8 -33.9 10.4 15.9 4.2 14 15 A F H < S+ 0 0 70 -4,-0.7 -2,-0.2 -3,-0.4 -3,-0.1 0.559 106.1 80.8-135.8 -20.1 12.2 18.6 2.4 15 16 A G S >< S- 0 0 25 -4,-2.8 3,-2.0 1,-0.2 5,-0.3 -0.037 91.1 -43.1 -92.0-169.2 15.7 17.6 1.0 16 17 A N T 3 S+ 0 0 139 1,-0.3 -1,-0.2 3,-0.1 216,-0.1 -0.353 129.2 4.6 -56.4 130.6 17.0 15.8 -2.0 17 18 A Y T 3 S+ 0 0 71 1,-0.2 -1,-0.3 -3,-0.1 215,-0.1 0.626 104.9 124.4 63.1 18.0 14.9 12.7 -2.8 18 19 A G S < S- 0 0 2 -3,-2.0 -5,-0.2 -7,-0.1 -1,-0.2 -0.236 77.4 -98.3 -90.3-171.9 12.5 13.6 0.0 19 20 A V - 0 0 0 -7,-2.0 312,-2.7 311,-0.1 313,-0.4 0.414 40.6-125.8 -97.6 1.7 8.7 14.0 -0.4 20 21 A K > + 0 0 62 -5,-0.3 4,-0.7 310,-0.2 3,-0.4 0.833 55.2 150.9 57.9 37.0 8.5 17.9 -0.6 21 22 A A H >> + 0 0 0 -8,-2.0 4,-2.3 1,-0.2 3,-0.6 0.846 64.2 63.4 -67.4 -34.1 6.0 18.1 2.2 22 23 A N H 3> S+ 0 0 29 -9,-0.8 4,-2.6 1,-0.2 -1,-0.2 0.858 95.9 58.2 -56.1 -39.5 7.3 21.6 3.2 23 24 A K H 3> S+ 0 0 95 -3,-0.4 4,-0.9 1,-0.2 -1,-0.2 0.844 109.5 44.6 -60.4 -35.0 6.2 23.0 -0.2 24 25 A V H <<>S+ 0 0 0 -4,-0.7 5,-2.0 -3,-0.6 4,-0.5 0.891 109.8 53.3 -79.1 -41.4 2.6 21.9 0.6 25 26 A W H ><5S+ 0 0 17 -4,-2.3 3,-1.6 1,-0.2 -2,-0.2 0.919 107.5 54.0 -54.1 -45.5 2.7 23.2 4.2 26 27 A D H 3<5S+ 0 0 124 -4,-2.6 -1,-0.2 1,-0.3 -2,-0.2 0.816 103.8 55.0 -56.7 -34.7 3.8 26.5 2.6 27 28 A R T 3<5S- 0 0 114 -4,-0.9 -1,-0.3 -3,-0.2 -2,-0.2 0.537 125.2-106.0 -76.8 -8.4 0.7 26.4 0.4 28 29 A G T < 5S+ 0 0 43 -3,-1.6 2,-0.5 -4,-0.5 -3,-0.2 0.502 80.1 124.7 96.5 7.3 -1.5 26.0 3.6 29 30 A F < + 0 0 31 -5,-2.0 -1,-0.3 1,-0.1 -2,-0.2 -0.880 14.8 151.2-105.4 128.5 -2.4 22.3 3.3 30 31 A T S S- 0 0 13 -2,-0.5 98,-3.1 257,-0.1 99,-0.9 0.254 74.2 -84.6-137.4 5.5 -1.5 20.1 6.3 31 32 A G > + 0 0 0 257,-0.3 3,-2.0 97,-0.3 99,-0.2 0.591 62.8 179.7 92.5 13.1 -4.2 17.3 6.2 32 33 A Q T 3 + 0 0 86 1,-0.3 97,-0.2 97,-0.1 -1,-0.2 -0.180 68.0 12.8 -45.4 129.3 -6.8 19.3 8.1 33 34 A G T 3 S+ 0 0 72 95,-0.7 2,-0.4 1,-0.2 -1,-0.3 0.559 99.8 120.8 79.9 8.5 -10.0 17.3 8.6 34 35 A V < - 0 0 2 -3,-2.0 96,-2.3 94,-0.1 2,-0.5 -0.878 49.1-152.9-107.9 137.6 -8.5 14.0 7.5 35 36 A V E -a 130 0A 25 -2,-0.4 135,-1.7 133,-0.2 136,-1.4 -0.938 11.0-171.0-107.2 127.5 -8.3 10.9 9.7 36 37 A V E -ab 131 171A 0 94,-2.9 96,-2.2 -2,-0.5 2,-0.3 -0.974 11.7-145.5-115.8 131.4 -5.5 8.4 9.1 37 38 A S E -ab 132 172A 0 134,-2.9 136,-2.8 -2,-0.5 2,-0.5 -0.739 2.5-155.9 -92.5 145.0 -5.5 5.0 10.8 38 39 A V E -ab 133 173A 4 94,-2.3 96,-2.9 -2,-0.3 2,-0.9 -0.947 4.4-164.7-119.8 107.3 -2.2 3.3 11.8 39 40 A V E +a 134 0A 0 134,-2.7 136,-0.5 -2,-0.5 96,-0.2 -0.829 52.0 90.8 -95.2 101.2 -2.7 -0.5 12.0 40 41 A D E S-a 135 0A 0 94,-1.8 96,-2.9 -2,-0.9 97,-2.1 -0.581 89.9 -32.4-162.5-150.0 0.4 -1.4 14.0 41 42 A T S S- 0 0 2 1,-0.3 39,-0.3 94,-0.2 38,-0.3 0.476 88.9-108.0 -77.3 -4.5 1.9 -2.0 17.5 42 43 A G - 0 0 4 92,-0.2 2,-0.3 -4,-0.2 -1,-0.3 -0.688 43.8 -59.8 105.3-162.8 -0.3 0.6 19.2 43 44 A I B -l 77 0B 24 33,-2.2 35,-2.9 -2,-0.2 2,-0.3 -0.903 31.4-135.5-130.9 149.2 0.5 4.0 20.6 44 45 A L - 0 0 6 -2,-0.3 2,-0.9 33,-0.2 35,-0.1 -0.734 30.3-113.1 -94.0 147.6 2.8 5.6 23.2 45 46 A D + 0 0 133 -2,-0.3 2,-0.4 33,-0.1 222,-0.1 -0.788 60.2 162.3 -72.3 106.0 1.8 8.4 25.6 46 47 A H >> - 0 0 0 -2,-0.9 4,-2.8 1,-0.1 3,-2.4 -0.993 48.5-138.9-143.6 124.2 4.1 10.9 24.0 47 48 A V T 34 S+ 0 0 91 -2,-0.4 4,-0.4 1,-0.3 -1,-0.1 0.805 108.3 50.2 -50.0 -36.3 4.1 14.7 24.2 48 49 A D T 34 S+ 0 0 0 1,-0.1 67,-2.5 2,-0.1 -1,-0.3 0.298 120.8 34.0 -90.7 9.5 4.8 15.0 20.5 49 50 A L T X4 S+ 0 0 0 -3,-2.4 3,-1.9 65,-0.2 4,-0.3 0.663 94.9 77.7-123.3 -40.1 1.9 12.6 19.6 50 51 A N G >< S+ 0 0 72 -4,-2.8 3,-1.6 1,-0.3 -3,-0.1 0.789 89.1 56.6 -50.2 -46.2 -1.0 13.0 22.0 51 52 A G G 3 S+ 0 0 53 -4,-0.4 -1,-0.3 1,-0.3 -3,-0.1 0.697 112.6 43.4 -63.2 -20.6 -2.6 16.2 20.6 52 53 A N G < S+ 0 0 12 -3,-1.9 79,-2.6 61,-0.1 2,-0.4 0.311 94.6 97.2-108.1 4.5 -3.0 14.6 17.2 53 54 A M B < -c 131 0A 34 -3,-1.6 79,-0.2 -4,-0.3 3,-0.1 -0.788 52.4-163.4 -97.8 139.1 -4.3 11.1 18.3 54 55 A L - 0 0 50 77,-3.4 -2,-0.1 -2,-0.4 113,-0.0 -0.684 44.8 -66.7-108.4 166.1 -8.0 10.2 18.3 55 56 A P + 0 0 90 0, 0.0 112,-0.1 0, 0.0 2,-0.1 -0.300 61.4 174.7 -55.1 132.2 -9.5 7.2 20.2 56 57 A G - 0 0 12 18,-0.3 2,-0.3 76,-0.1 78,-0.2 -0.256 21.0-117.5-115.4-153.4 -8.4 3.9 18.7 57 58 A Y E -d 134 0A 21 76,-1.4 78,-2.3 -2,-0.1 2,-0.7 -0.987 9.2-128.8-155.9 148.2 -8.9 0.2 19.6 58 59 A D E +dE 135 73A 0 15,-2.8 15,-1.9 -2,-0.3 78,-0.2 -0.877 24.5 174.6-103.6 107.6 -6.8 -2.8 20.7 59 60 A F + 0 0 0 76,-3.2 2,-0.5 -2,-0.7 13,-0.2 0.381 34.1 126.6 -93.5 1.9 -7.6 -5.8 18.5 60 61 A I - 0 0 5 75,-0.5 6,-0.1 11,-0.2 77,-0.1 -0.500 39.2-169.4 -68.1 114.3 -4.9 -8.2 19.8 61 62 A S + 0 0 30 -2,-0.5 2,-0.8 10,-0.1 -1,-0.2 0.764 64.9 83.1 -77.3 -28.6 -6.8 -11.3 20.8 62 63 A S > - 0 0 16 1,-0.2 4,-1.7 9,-0.1 5,-0.1 -0.712 61.8-163.5 -79.9 110.2 -3.9 -12.9 22.7 63 64 A A H >>S+ 0 0 29 -2,-0.8 4,-1.1 2,-0.2 5,-0.7 0.891 90.2 53.1 -57.2 -45.0 -3.7 -11.5 26.2 64 65 A P H >45S+ 0 0 90 0, 0.0 3,-0.5 0, 0.0 -1,-0.2 0.931 112.5 42.8 -53.1 -51.0 -0.1 -12.8 26.6 65 66 A N H 345S+ 0 0 30 1,-0.2 74,-2.3 73,-0.1 -2,-0.2 0.748 111.8 54.6 -73.7 -22.5 1.1 -11.1 23.4 66 67 A A H 3<5S- 0 0 0 -4,-1.7 13,-0.3 72,-0.2 -1,-0.2 0.665 90.2-151.9 -81.5 -19.5 -0.8 -7.9 24.2 67 68 A R T <<5 + 0 0 62 -4,-1.1 -4,-0.1 -3,-0.5 -2,-0.1 0.722 67.6 100.1 54.5 30.6 0.9 -7.5 27.7 68 69 A D S S+ 0 0 58 11,-2.7 3,-2.5 10,-0.1 5,-0.3 0.775 83.6 158.7 55.2 31.7 13.2 -17.4 21.5 87 88 A D T 3 S+ 0 0 81 10,-0.5 -1,-0.1 -3,-0.5 3,-0.1 0.708 74.2 49.3 -56.3 -22.9 9.9 -16.5 23.3 88 89 A a T 3 S- 0 0 27 1,-0.4 -1,-0.3 8,-0.4 -2,-0.1 0.053 121.0-105.3-105.9 22.6 8.3 -16.1 19.8 89 90 A G S < S+ 0 0 33 -3,-2.5 -1,-0.4 -4,-0.1 -3,-0.0 -0.218 78.9 108.7 89.4-179.5 9.6 -19.4 18.5 90 91 A G > - 0 0 26 1,-0.3 3,-2.2 -3,-0.1 6,-0.2 0.400 53.1-165.2 92.6 -1.5 12.4 -20.4 16.1 91 92 A Y T 3 + 0 0 174 1,-0.3 -1,-0.3 -5,-0.3 -5,-0.0 -0.333 67.9 23.0 -52.2 138.3 15.0 -22.0 18.4 92 93 A P T 3 S+ 0 0 86 0, 0.0 -1,-0.3 0, 0.0 5,-0.1 -0.920 91.8 106.8 -98.7 18.3 17.8 -22.5 17.7 93 94 A D X - 0 0 69 -3,-2.2 3,-2.1 1,-0.2 4,-0.2 -0.392 60.0-148.5 -58.2 114.1 18.0 -19.9 14.8 94 95 A P G > S+ 0 0 77 0, 0.0 3,-0.9 0, 0.0 4,-0.4 0.734 93.5 66.8 -58.8 -24.5 20.1 -17.0 16.2 95 96 A R G 3 S+ 0 0 194 1,-0.2 3,-0.1 2,-0.1 -2,-0.1 0.669 104.4 43.1 -68.7 -19.6 18.1 -14.6 14.1 96 97 A R G < S+ 0 0 117 -3,-2.1 -8,-0.4 -6,-0.2 -1,-0.2 0.290 85.3 97.2-111.8 7.1 15.0 -15.3 16.2 97 98 A E S < S- 0 0 58 -3,-0.9 -11,-2.7 -4,-0.2 -10,-0.5 0.938 90.9 -12.2 -62.7 -50.5 16.5 -15.3 19.7 98 99 A K - 0 0 131 -4,-0.4 2,-0.3 -14,-0.2 -14,-0.2 -0.977 48.3-174.3-154.7 156.8 15.7 -11.7 20.8 99 100 A K B -M 83 0C 74 -16,-2.7 -16,-1.9 -2,-0.3 2,-0.2 -0.975 23.2-127.5-154.0 147.6 14.5 -8.2 19.9 100 101 A F - 0 0 122 -2,-0.3 162,-0.2 -18,-0.2 161,-0.1 -0.497 52.8 -76.2 -82.0 162.2 14.2 -4.8 21.7 101 102 A S - 0 0 12 160,-2.0 -1,-0.1 -2,-0.2 157,-0.1 -0.388 39.1-159.0 -59.8 134.4 10.8 -3.0 21.6 102 103 A T - 0 0 31 -2,-0.1 -1,-0.1 -3,-0.1 5,-0.1 0.762 8.7-152.7 -86.8 -30.1 10.3 -1.3 18.2 103 104 A W > + 0 0 5 154,-0.1 4,-2.2 3,-0.1 3,-0.5 0.828 39.3 158.4 51.9 33.9 7.7 1.4 19.2 104 105 A H H > + 0 0 32 1,-0.2 4,-3.0 2,-0.2 5,-0.2 0.866 59.4 52.2 -55.9 -50.8 6.8 0.9 15.5 105 106 A G H > S+ 0 0 0 1,-0.2 4,-2.3 2,-0.2 -1,-0.2 0.813 112.6 46.6 -59.7 -33.9 3.3 2.2 15.7 106 107 A S H > S+ 0 0 0 -3,-0.5 4,-2.1 2,-0.2 150,-0.5 0.850 111.6 49.6 -77.0 -39.0 4.4 5.4 17.3 107 108 A H H X S+ 0 0 0 -4,-2.2 4,-1.5 2,-0.2 149,-0.4 0.954 116.2 44.2 -62.5 -48.2 7.3 6.0 14.9 108 109 A V H X S+ 0 0 0 -4,-3.0 4,-1.6 1,-0.2 -2,-0.2 0.917 112.7 50.8 -59.9 -48.4 4.9 5.4 12.0 109 110 A A H X S+ 0 0 0 -4,-2.3 4,-2.9 1,-0.2 -1,-0.2 0.848 108.2 53.9 -60.3 -36.2 2.2 7.6 13.6 110 111 A G H X S+ 0 0 0 -4,-2.1 4,-2.0 146,-0.3 -1,-0.2 0.847 103.5 54.8 -66.7 -37.2 4.8 10.4 14.1 111 112 A T H < S+ 0 0 0 -4,-1.5 14,-2.8 -3,-0.2 15,-0.3 0.888 115.7 40.6 -63.2 -37.7 5.7 10.3 10.4 112 113 A I H < S- 0 0 0 -4,-1.6 14,-2.9 12,-0.2 17,-0.2 0.935 141.0 -8.0 -72.8 -50.2 2.0 10.9 9.6 113 114 A A H < + 0 0 0 -4,-2.9 -3,-0.2 12,-0.2 -2,-0.2 -0.081 67.9 164.3-154.9 42.8 1.0 13.5 12.2 114 115 A A < - 0 0 0 -4,-2.0 10,-0.5 9,-0.1 2,-0.3 -0.359 60.1 -90.2 -55.0 143.3 3.6 14.3 15.0 115 116 A V - 0 0 27 -67,-2.5 3,-0.3 8,-0.1 2,-0.3 -0.499 58.4-160.4 -63.7 123.2 2.5 17.5 16.7 116 117 A T + 0 0 18 -2,-0.3 7,-0.1 11,-0.3 5,-0.1 -0.750 58.3 22.0-118.8 154.1 4.3 20.1 14.7 117 118 A N S S+ 0 0 94 -2,-0.3 -1,-0.2 1,-0.1 6,-0.1 0.830 85.2 119.2 56.6 37.0 5.4 23.7 15.2 118 119 A N S S- 0 0 58 -3,-0.3 -1,-0.1 2,-0.3 -2,-0.1 0.145 84.8-111.6-116.0 16.1 5.2 23.1 19.0 119 120 A G S S+ 0 0 47 1,-0.1 2,-0.3 2,-0.1 -115,-0.1 0.599 87.7 84.9 70.4 14.6 8.8 23.8 19.9 120 121 A V S S- 0 0 54 2,-0.2 -2,-0.3 -5,-0.2 2,-0.1 -0.999 86.7 -26.3-150.5 142.5 9.7 20.2 20.7 121 122 A G S S- 0 0 4 -2,-0.3 -115,-2.6 -117,-0.1 -114,-0.4 -0.324 92.7 -27.4 64.0-125.1 10.7 17.0 18.9 122 123 A V - 0 0 0 -116,-0.2 2,-0.2 -117,-0.2 -4,-0.2 -0.505 50.3-111.7-123.4 177.7 9.8 16.5 15.3 123 124 A A - 0 0 0 -2,-0.2 2,-0.3 -7,-0.1 -8,-0.1 -0.713 21.8-139.8-108.3 165.6 7.3 17.3 12.5 124 125 A G > - 0 0 0 -10,-0.5 3,-0.8 -2,-0.2 -12,-0.2 -0.917 19.7-122.9-122.0 154.1 4.8 15.1 10.7 125 126 A V T 3 S+ 0 0 0 -14,-2.8 2,-0.3 -2,-0.3 -13,-0.2 0.894 112.1 26.2 -59.6 -45.5 3.9 15.1 7.0 126 127 A A T > S+ 0 0 0 -14,-2.9 3,-1.7 -15,-0.3 -1,-0.3 -0.578 73.7 159.6-119.1 66.8 0.2 15.7 7.6 127 128 A Y T < S+ 0 0 58 -3,-0.8 -11,-0.3 -2,-0.3 -96,-0.2 0.536 71.1 60.5 -77.1 -4.5 0.3 17.5 10.9 128 129 A G T 3 S+ 0 0 21 -98,-3.1 -95,-0.7 -3,-0.1 -1,-0.3 0.598 96.3 79.9 -88.2 -17.4 -3.1 19.0 10.5 129 130 A A S < S- 0 0 0 -3,-1.7 2,-0.3 -99,-0.9 -94,-0.2 -0.188 76.5-126.1 -79.2 174.9 -4.6 15.5 10.3 130 131 A K E -a 35 0A 72 -96,-2.3 -94,-2.9 -99,-0.2 2,-0.4 -0.953 14.6-140.6-124.4 149.6 -5.5 13.1 13.1 131 132 A V E -ac 36 53A 0 -79,-2.6 -77,-3.4 -2,-0.3 -94,-0.2 -0.888 3.4-156.8-110.9 135.5 -4.4 9.5 13.7 132 133 A I E -a 37 0A 0 -96,-2.2 -94,-2.3 -2,-0.4 2,-0.5 -0.956 19.6-143.3-106.4 112.5 -6.4 6.6 15.1 133 134 A P E -a 38 0A 4 0, 0.0 -76,-1.4 0, 0.0 2,-0.7 -0.645 15.2-170.0 -73.8 118.0 -4.0 3.9 16.5 134 135 A V E -ad 39 57A 0 -96,-2.9 -94,-1.8 -2,-0.5 2,-0.6 -0.922 13.5-148.0-115.8 103.3 -5.4 0.5 15.8 135 136 A R E +ad 40 58A 0 -78,-2.3 -76,-3.2 -2,-0.7 -75,-0.5 -0.638 43.1 137.5 -85.0 117.5 -3.4 -2.0 17.8 136 137 A V + 0 0 0 -96,-2.9 2,-0.5 -2,-0.6 7,-0.3 0.430 53.8 74.4-130.9 -12.2 -3.0 -5.4 16.1 137 138 A L + 0 0 24 -97,-2.1 5,-0.2 5,-0.1 2,-0.1 -0.938 51.6 156.0-116.1 126.6 0.7 -6.3 16.7 138 139 A G B > -N 141 0D 1 3,-2.7 3,-2.1 -2,-0.5 -72,-0.2 -0.341 61.3 -36.9-121.1-153.9 2.1 -7.4 20.0 139 140 A K T 3 S+ 0 0 27 -74,-2.3 3,-0.1 1,-0.3 -51,-0.1 0.797 139.0 26.6 -37.5 -52.0 5.1 -9.4 21.3 140 141 A a T 3 S- 0 0 55 1,-0.4 -1,-0.3 -53,-0.1 2,-0.2 -0.128 119.7 -97.7-111.9 37.0 5.1 -12.0 18.4 141 142 A G B < -N 138 0D 32 -3,-2.1 -3,-2.7 -76,-0.1 -1,-0.4 -0.602 60.3 -62.0 80.9-146.4 3.5 -9.9 15.7 142 143 A G - 0 0 32 -5,-0.2 2,-0.2 -2,-0.2 -5,-0.1 -0.972 37.0-104.8-141.8 154.7 -0.2 -10.3 15.1 143 144 A Y > - 0 0 122 -2,-0.3 4,-2.2 -7,-0.3 3,-0.5 -0.558 35.2-123.1 -71.1 141.4 -2.9 -12.8 14.0 144 145 A D H > S+ 0 0 52 1,-0.2 4,-2.5 -2,-0.2 5,-0.2 0.896 112.1 50.3 -51.1 -47.1 -4.1 -12.3 10.4 145 146 A S H > S+ 0 0 65 1,-0.2 4,-2.0 2,-0.2 -1,-0.2 0.807 108.6 52.0 -68.3 -29.7 -7.7 -11.9 11.6 146 147 A D H > S+ 0 0 2 -3,-0.5 4,-2.0 2,-0.2 -1,-0.2 0.899 111.3 48.9 -68.0 -41.3 -6.7 -9.3 14.2 147 148 A I H X S+ 0 0 5 -4,-2.2 4,-2.3 2,-0.2 -2,-0.2 0.927 115.8 40.9 -61.9 -49.3 -4.9 -7.3 11.5 148 149 A T H X S+ 0 0 1 -4,-2.5 4,-2.2 2,-0.2 -2,-0.2 0.827 113.0 53.3 -77.0 -32.3 -7.8 -7.4 9.0 149 150 A D H X S+ 0 0 34 -4,-2.0 4,-2.8 -5,-0.2 5,-0.2 0.936 112.9 46.0 -59.7 -47.7 -10.6 -6.8 11.6 150 151 A G H X S+ 0 0 0 -4,-2.0 4,-2.3 2,-0.2 -2,-0.2 0.915 111.5 50.6 -61.4 -48.7 -8.6 -3.7 12.8 151 152 A M H X S+ 0 0 0 -4,-2.3 4,-0.8 2,-0.2 -1,-0.2 0.925 114.8 44.2 -51.1 -50.8 -8.0 -2.5 9.2 152 153 A Y H ><>S+ 0 0 41 -4,-2.2 5,-2.5 1,-0.2 3,-0.9 0.919 113.0 49.4 -65.5 -48.7 -11.7 -2.8 8.5 153 154 A W H ><5S+ 0 0 10 -4,-2.8 3,-1.5 1,-0.2 -1,-0.2 0.859 104.3 61.4 -57.9 -37.4 -12.9 -1.2 11.7 154 155 A S H 3<5S+ 0 0 0 -4,-2.3 15,-2.9 1,-0.3 -1,-0.2 0.790 103.9 48.7 -64.3 -27.4 -10.5 1.7 11.1 155 156 A A T <<5S- 0 0 10 -3,-0.9 -1,-0.3 -4,-0.8 -2,-0.2 0.483 135.5 -87.6 -87.6 -4.2 -12.4 2.5 7.9 156 157 A G T < 5S+ 0 0 36 -3,-1.5 -3,-0.2 -4,-0.4 2,-0.2 0.498 76.8 152.0 107.3 9.4 -15.7 2.4 9.8 157 158 A G < - 0 0 2 -5,-2.5 2,-0.3 -6,-0.2 8,-0.3 -0.494 46.9-115.7 -70.0 137.1 -16.5 -1.3 9.4 158 159 A H - 0 0 97 -2,-0.2 2,-0.4 6,-0.1 -1,-0.1 -0.607 28.8-170.5 -76.1 129.8 -18.6 -3.0 12.1 159 160 A I > - 0 0 17 3,-0.4 3,-2.0 -2,-0.3 2,-0.1 -0.991 30.0-111.6-119.5 126.8 -17.0 -5.7 14.3 160 161 A D T 3 S+ 0 0 138 -2,-0.4 -2,-0.0 1,-0.3 0, 0.0 -0.316 102.7 14.5 -55.2 129.1 -19.2 -7.8 16.6 161 162 A G T 3 S+ 0 0 80 1,-0.2 -1,-0.3 -2,-0.1 0, 0.0 0.501 107.4 102.6 80.6 5.1 -18.4 -7.0 20.3 162 163 A V S < S- 0 0 9 -3,-2.0 -3,-0.4 -105,-0.0 -1,-0.2 -0.980 78.6-114.7-119.2 129.3 -16.5 -3.8 19.4 163 164 A P - 0 0 85 0, 0.0 2,-0.1 0, 0.0 -4,-0.1 -0.337 47.4 -92.5 -58.4 143.1 -18.1 -0.3 19.7 164 165 A D - 0 0 87 1,-0.1 2,-0.4 -6,-0.1 -6,-0.1 -0.370 41.5-107.0 -64.5 131.7 -18.5 1.3 16.4 165 166 A N - 0 0 14 -8,-0.3 -1,-0.1 -12,-0.2 -109,-0.0 -0.437 29.6-170.5 -61.1 116.6 -15.6 3.5 15.2 166 167 A Q S S+ 0 0 150 -2,-0.4 -1,-0.2 1,-0.2 -2,-0.1 0.447 80.8 54.6 -92.1 -0.4 -16.8 7.2 15.5 167 168 A N S S- 0 0 46 -112,-0.1 -1,-0.2 -113,-0.0 -11,-0.1 -0.541 77.8-168.7-128.2 67.3 -13.7 8.4 13.7 168 169 A P - 0 0 70 0, 0.0 2,-0.3 0, 0.0 -13,-0.2 -0.324 18.5-129.3 -59.3 136.2 -13.6 6.5 10.3 169 170 A A - 0 0 5 -15,-2.9 -133,-0.2 1,-0.1 3,-0.1 -0.689 17.3-162.2 -93.0 138.1 -10.3 6.9 8.4 170 171 A Q S S+ 0 0 76 -135,-1.7 29,-2.7 -2,-0.3 2,-0.4 0.621 88.1 43.8 -85.5 -19.2 -10.0 7.9 4.8 171 172 A V E S-bf 36 199A 0 -136,-1.4 -134,-2.9 27,-0.2 2,-0.6 -0.998 70.5-162.7-129.5 128.3 -6.4 6.6 4.7 172 173 A V E -bf 37 200A 0 27,-3.1 29,-2.9 -2,-0.4 2,-0.6 -0.929 7.4-159.4-116.4 106.2 -5.4 3.2 6.3 173 174 A N E -bf 38 201A 0 -136,-2.8 -134,-2.7 -2,-0.6 2,-0.6 -0.780 10.5-179.0 -88.6 118.0 -1.7 2.8 6.9 174 175 A M E + f 0 202A 0 27,-3.3 29,-1.8 -2,-0.6 2,-1.4 -0.825 6.3 175.7-118.2 91.2 -0.6 -0.8 7.3 175 176 A S + 0 0 2 -2,-0.6 2,-0.3 -136,-0.5 101,-0.1 -0.445 55.1 88.2 -91.0 59.8 3.2 -0.8 8.0 176 177 A L - 0 0 14 -2,-1.4 27,-0.3 27,-0.2 2,-0.1 -0.927 50.7-172.9-150.8 168.0 3.2 -4.6 8.4 177 178 A G - 0 0 36 -2,-0.3 2,-0.2 39,-0.1 28,-0.1 -0.339 10.0-162.1-139.8-138.9 3.5 -7.8 6.5 178 179 A G - 0 0 40 -2,-0.1 37,-2.4 37,-0.1 -2,-0.0 -0.445 40.2 -88.0 141.0 135.6 3.2 -11.6 6.7 179 180 A G B S+O 214 0E 74 35,-0.2 35,-0.2 -2,-0.2 34,-0.0 -0.270 80.2 24.9 -70.3 154.2 4.6 -14.2 4.4 180 181 A G S S- 0 0 36 33,-1.7 38,-0.2 2,-0.1 3,-0.1 0.095 88.6 -48.6 88.1 167.4 2.9 -15.6 1.3 181 182 A G S S- 0 0 51 1,-0.1 2,-0.6 33,-0.1 34,-0.2 0.090 72.7 -68.2 -67.0-177.6 0.2 -14.5 -1.2 182 183 A b - 0 0 37 30,-0.2 -1,-0.1 36,-0.1 -2,-0.1 -0.648 45.5-138.0 -85.8 116.6 -3.2 -13.0 -0.4 183 184 A S > - 0 0 61 -2,-0.6 4,-2.5 1,-0.1 5,-0.2 -0.310 23.4-114.4 -64.7 152.7 -5.8 -15.2 1.2 184 185 A Q H > S+ 0 0 158 1,-0.2 4,-1.9 2,-0.2 -1,-0.1 0.871 117.5 48.8 -55.9 -41.9 -9.4 -15.1 0.0 185 186 A N H > S+ 0 0 79 2,-0.2 4,-2.7 1,-0.2 -1,-0.2 0.915 109.4 50.9 -66.5 -45.3 -10.6 -13.7 3.4 186 187 A S H > S+ 0 0 5 1,-0.2 4,-2.8 2,-0.2 -2,-0.2 0.943 111.8 47.9 -57.1 -49.2 -7.9 -11.0 3.5 187 188 A Q H X S+ 0 0 31 -4,-2.5 4,-2.8 2,-0.2 -1,-0.2 0.883 110.7 52.1 -56.8 -42.8 -8.8 -9.8 0.0 188 189 A R H X S+ 0 0 119 -4,-1.9 4,-2.3 -5,-0.2 -2,-0.2 0.942 112.0 45.3 -58.8 -50.2 -12.5 -9.8 1.0 189 190 A M H X S+ 0 0 13 -4,-2.7 4,-2.0 1,-0.2 -2,-0.2 0.889 113.6 50.7 -61.4 -41.3 -11.7 -7.7 4.0 190 191 A I H X S+ 0 0 0 -4,-2.8 4,-2.6 2,-0.2 -2,-0.2 0.904 110.6 47.9 -62.0 -46.3 -9.4 -5.4 1.9 191 192 A D H X S+ 0 0 48 -4,-2.8 4,-2.5 2,-0.2 -2,-0.2 0.892 110.9 51.5 -63.3 -42.3 -12.1 -4.9 -0.8 192 193 A K H X S+ 0 0 82 -4,-2.3 4,-0.7 -5,-0.2 -2,-0.2 0.906 112.1 47.4 -58.7 -44.8 -14.8 -4.1 1.9 193 194 A T H ><>S+ 0 0 0 -4,-2.0 5,-1.2 2,-0.2 3,-0.8 0.940 114.2 45.3 -63.0 -51.0 -12.4 -1.5 3.5 194 195 A T H ><5S+ 0 0 15 -4,-2.6 3,-1.9 1,-0.2 -2,-0.2 0.893 108.6 56.8 -58.5 -45.0 -11.5 0.2 0.1 195 196 A N H 3<5S+ 0 0 133 -4,-2.5 -1,-0.2 1,-0.3 -2,-0.2 0.632 95.2 65.5 -70.0 -14.3 -15.2 0.2 -1.0 196 197 A L T <<5S- 0 0 99 -3,-0.8 -1,-0.3 -4,-0.7 -2,-0.2 0.676 129.5 -95.6 -72.2 -19.8 -16.1 2.2 2.1 197 198 A G T < 5S+ 0 0 34 -3,-1.9 2,-0.4 -4,-0.4 -3,-0.2 0.475 82.4 132.1 117.4 9.4 -13.9 5.0 0.6 198 199 A A < - 0 0 1 -5,-1.2 2,-0.6 -4,-0.1 -1,-0.3 -0.773 50.5-137.4 -99.7 133.5 -10.6 4.3 2.4 199 200 A L E -f 171 0A 8 -29,-2.7 -27,-3.1 -2,-0.4 2,-0.6 -0.796 17.7-147.8 -86.8 119.5 -7.2 4.2 0.7 200 201 A I E -f 172 0A 0 -2,-0.6 23,-3.0 21,-0.5 2,-0.5 -0.816 14.5-170.5 -92.8 120.4 -5.1 1.3 2.1 201 202 A V E -fg 173 223A 0 -29,-2.9 -27,-3.3 -2,-0.6 2,-0.3 -0.949 10.1-175.3-115.8 128.0 -1.4 2.1 2.0 202 203 A I E -fg 174 224A 0 21,-2.8 23,-3.2 -2,-0.5 2,-0.3 -0.930 30.5-112.4-132.2 146.3 1.0 -0.7 2.8 203 204 A A E - g 0 225A 3 -29,-1.8 14,-0.3 -2,-0.3 23,-0.2 -0.615 25.9-137.8 -70.3 132.0 4.7 -1.3 3.4 204 205 A A - 0 0 1 21,-2.5 13,-0.2 -2,-0.3 22,-0.1 0.747 51.8-105.7 -63.4 -26.9 6.1 -3.5 0.5 205 206 A G - 0 0 10 20,-0.3 34,-3.0 34,-0.1 3,-0.2 -0.187 12.8-110.3 109.6 158.3 8.1 -5.6 3.0 206 207 A N S S+ 0 0 66 32,-0.2 32,-0.2 1,-0.2 -1,-0.1 -0.131 81.1 99.2-119.0 35.5 11.7 -6.0 4.1 207 208 A E S S- 0 0 102 2,-0.1 31,-0.2 3,-0.0 -1,-0.2 0.304 86.1-120.7-107.0 8.3 12.9 -9.4 2.8 208 209 A N S S+ 0 0 78 29,-2.4 2,-0.2 -3,-0.2 31,-0.2 0.903 77.3 109.4 50.1 47.5 14.7 -8.2 -0.4 209 210 A Q S S- 0 0 38 28,-0.3 31,-2.1 -4,-0.1 2,-0.4 -0.707 81.6 -62.8-134.0-175.5 12.3 -10.3 -2.5 210 211 A D B > -p 240 0F 54 -2,-0.2 3,-1.7 29,-0.2 31,-0.2 -0.643 41.2-138.1 -76.3 131.4 9.5 -9.9 -5.0 211 212 A A G > S+ 0 0 0 29,-2.8 3,-1.8 -2,-0.4 7,-0.2 0.700 97.1 74.5 -64.3 -22.3 6.5 -8.2 -3.2 212 213 A S G 3 S+ 0 0 53 28,-0.4 -1,-0.3 1,-0.3 -30,-0.2 0.619 90.9 59.0 -63.7 -13.8 4.1 -10.6 -5.0 213 214 A R G < S+ 0 0 152 -3,-1.7 -33,-1.7 -32,-0.1 2,-0.3 0.339 102.7 64.9 -97.2 3.7 5.3 -13.3 -2.5 214 215 A T B <> S-O 179 0E 4 -3,-1.8 4,-1.7 -35,-0.2 -35,-0.2 -0.930 85.4 -92.3-129.4 149.7 4.3 -11.3 0.5 215 216 A W T 4 S+ 0 0 21 -37,-2.4 -37,-0.1 -2,-0.3 -34,-0.1 -0.843 99.9 16.1 -97.9 141.2 1.0 -10.1 2.0 216 217 A P T >4 S+ 0 0 0 0, 0.0 3,-1.6 0, 0.0 -1,-0.2 -0.986 119.9 60.9 -90.0 -0.4 -0.5 -7.4 1.7 217 218 A S T 34 S+ 0 0 1 1,-0.3 -2,-0.2 -14,-0.3 -5,-0.1 0.744 101.2 57.6 -62.2 -23.2 1.4 -6.4 -1.5 218 219 A S T 3< S+ 0 0 20 -4,-1.7 -1,-0.3 -38,-0.2 -36,-0.1 0.680 93.8 90.7 -75.8 -19.8 0.1 -9.5 -3.3 219 220 A b S < S- 0 0 1 -3,-1.6 3,-0.4 -5,-0.2 2,-0.2 -0.337 79.4-119.7 -71.3 155.2 -3.4 -8.3 -2.6 220 221 A N S S+ 0 0 94 1,-0.2 3,-0.1 -2,-0.1 -1,-0.1 -0.481 89.7 37.2 -82.7 165.6 -5.4 -6.2 -5.0 221 222 A N S S+ 0 0 88 1,-0.2 -21,-0.5 -2,-0.2 2,-0.3 0.669 89.7 110.7 63.7 23.7 -6.8 -2.7 -4.0 222 223 A V - 0 0 11 -3,-0.4 2,-0.7 -5,-0.1 -1,-0.2 -0.941 66.6-130.5-121.1 149.0 -3.7 -1.7 -1.8 223 224 A L E -g 201 0A 1 -23,-3.0 -21,-2.8 -2,-0.3 2,-0.5 -0.899 28.9-151.0 -97.7 113.2 -1.1 1.0 -2.6 224 225 A S E -g 202 0A 0 -2,-0.7 21,-1.9 -23,-0.2 22,-1.4 -0.764 7.4-156.1 -99.3 122.6 2.2 -0.8 -2.0 225 226 A V E -gh 203 246A 0 -23,-3.2 -21,-2.5 -2,-0.5 -20,-0.3 -0.851 4.6-162.7-111.0 118.7 5.1 1.4 -0.9 226 227 A G E - h 0 247A 0 20,-2.5 22,-2.1 -2,-0.6 2,-0.5 -0.444 24.8-112.9 -85.0 166.2 8.8 0.6 -1.5 227 228 A A E - h 0 248A 0 12,-0.3 8,-2.6 20,-0.2 2,-0.3 -0.874 27.6-170.6-110.7 131.3 11.6 2.3 0.5 228 229 A T E -Ih 234 249A 0 20,-2.2 22,-3.4 -2,-0.5 23,-0.6 -0.747 15.0-129.5-110.0 165.4 14.3 4.6 -0.9 229 230 A T > - 0 0 22 4,-2.1 3,-2.0 -2,-0.3 23,-0.1 -0.475 37.8 -93.7-101.3 173.2 17.5 6.1 0.6 230 231 A P T 3 S+ 0 0 35 0, 0.0 -212,-0.1 0, 0.0 -1,-0.0 0.687 127.4 62.1 -57.7 -16.0 18.8 9.7 0.9 231 232 A K T 3 S- 0 0 140 2,-0.1 3,-0.1 -214,-0.1 -214,-0.1 0.550 116.4-116.4 -84.9 -8.8 20.7 8.7 -2.3 232 233 A G S < S+ 0 0 0 -3,-2.0 85,-2.5 1,-0.3 2,-0.3 0.792 77.6 118.3 75.3 30.1 17.3 8.2 -4.2 233 234 A K S S- 0 0 68 83,-0.2 -4,-2.1 87,-0.0 -1,-0.3 -0.769 75.8 -77.2-119.6 165.7 18.1 4.5 -4.6 234 235 A R B -I 228 0A 22 -2,-0.3 -6,-0.2 -6,-0.2 87,-0.1 -0.459 45.7-118.5 -65.5 128.1 16.3 1.3 -3.4 235 236 A A > - 0 0 0 -8,-2.6 3,-2.3 -2,-0.2 -8,-0.2 -0.541 28.5-120.7 -63.9 129.5 16.9 0.5 0.2 236 237 A P T 3 S+ 0 0 95 0, 0.0 -1,-0.1 0, 0.0 -2,-0.1 0.670 110.2 48.5 -54.8 -23.8 18.7 -3.0 0.1 237 238 A F T 3 S+ 0 0 47 -30,-0.1 -29,-2.4 -29,-0.1 -28,-0.3 0.631 85.1 117.5 -85.9 -19.2 15.9 -4.6 2.2 238 239 A S < - 0 0 0 -3,-2.3 -32,-0.2 -11,-0.2 -12,-0.1 -0.308 65.5-126.2 -63.2 124.7 13.0 -3.2 0.2 239 240 A N - 0 0 0 -34,-3.0 -12,-0.3 -31,-0.2 2,-0.2 -0.279 38.8-172.0 -57.1 155.3 10.7 -5.7 -1.5 240 241 A Y B +p 210 0F 26 -31,-2.1 -29,-2.8 -36,-0.1 -28,-0.4 -0.745 23.0 74.9-143.6 178.8 10.3 -4.9 -5.2 241 242 A G S > S- 0 0 16 82,-2.4 3,-1.6 -2,-0.2 84,-0.3 -0.546 88.5 -32.5 111.3-167.3 8.6 -5.6 -8.5 242 243 A A T 3 S+ 0 0 96 1,-0.3 -1,-0.2 -2,-0.2 82,-0.0 0.715 126.3 63.2 -65.2 -23.3 5.3 -5.0 -10.4 243 244 A R T 3 S+ 0 0 71 -3,-0.3 2,-0.5 -20,-0.0 -1,-0.3 0.423 86.2 84.5 -87.2 3.3 3.4 -5.2 -7.1 244 245 A V < - 0 0 5 -3,-1.6 81,-0.4 1,-0.1 -19,-0.2 -0.930 56.7-176.8 -99.6 125.9 5.2 -2.1 -5.8 245 246 A H - 0 0 63 -21,-1.9 81,-2.1 -2,-0.5 2,-0.3 0.773 60.3 -18.0 -97.1 -32.6 3.4 1.1 -7.1 246 247 A L E -h 225 0A 0 -22,-1.4 -20,-2.5 79,-0.3 2,-0.3 -0.934 61.8-124.8-158.4-179.6 5.7 3.9 -5.7 247 248 A A E -hj 226 328A 0 80,-2.4 82,-2.8 -2,-0.3 -20,-0.2 -0.888 14.1-172.8-133.1 162.4 8.4 4.6 -3.2 248 249 A A E -h 227 0A 0 -22,-2.1 -20,-2.2 -2,-0.3 30,-0.1 -0.965 49.7 -65.2-146.3 160.2 9.1 7.0 -0.3 249 250 A P E +h 228 0A 0 0, 0.0 -20,-0.2 0, 0.0 32,-0.2 -0.251 53.0 169.1 -48.3 126.9 12.1 7.6 2.0 250 251 A G + 0 0 0 -22,-3.4 24,-2.6 28,-0.1 2,-0.3 0.244 49.4 60.9-133.3 8.9 12.7 4.5 4.1 251 252 A T S S+ 0 0 17 -23,-0.6 22,-0.2 22,-0.2 3,-0.1 -0.975 100.7 18.4-136.3 154.5 16.1 4.9 5.8 252 253 A N S S+ 0 0 84 -2,-0.3 2,-0.7 1,-0.2 -240,-0.3 0.910 80.3 165.7 53.9 45.3 17.4 7.5 8.3 253 254 A I E -Q 272 0G 0 19,-2.0 19,-1.5 -3,-0.1 2,-0.5 -0.852 25.0-152.1 -98.4 110.1 13.8 8.3 9.1 254 255 A L E +Q 271 0G 8 -2,-0.7 2,-0.2 17,-0.2 17,-0.2 -0.723 34.1 132.4 -86.6 127.6 13.5 10.4 12.3 255 256 A S E -Q 270 0G 0 15,-1.8 15,-2.4 -2,-0.5 2,-0.3 -0.874 54.2 -50.8-155.5-170.5 10.3 10.1 14.3 256 257 A T E +Q 269 0G 0 -150,-0.5 -146,-0.3 -149,-0.4 13,-0.3 -0.566 60.0 141.4 -82.1 131.5 8.7 9.6 17.7 257 258 A I E -Q 268 0G 26 11,-2.4 11,-2.7 -2,-0.3 2,-0.3 -0.744 44.8-108.0-145.2-175.6 9.7 6.6 19.9 258 259 A D E -Q 267 0G 9 9,-0.3 9,-0.2 -2,-0.2 -212,-0.0 -0.937 20.6-132.0-119.7 154.5 10.4 5.6 23.5 259 260 A V S S+ 0 0 59 7,-2.5 8,-0.1 -2,-0.3 -1,-0.0 0.700 71.6 114.6 -75.2 -19.4 13.9 4.9 25.0 260 261 A G - 0 0 7 6,-0.2 -2,-0.2 1,-0.1 -159,-0.1 -0.231 51.6-162.9 -60.6 135.6 12.7 1.7 26.6 261 262 A Q S S+ 0 0 120 -161,-0.1 -160,-2.0 2,-0.1 -1,-0.1 0.644 91.3 9.6 -89.0 -19.9 14.1 -1.6 25.3 262 263 A A S S+ 0 0 38 1,-0.6 -180,-0.3 -162,-0.2 -181,-0.1 0.356 132.1 5.0-117.2-104.6 11.2 -3.5 27.0 263 264 A G S S- 0 0 24 1,-0.2 -1,-0.6 -183,-0.1 -183,-0.1 -0.318 98.7 -70.1 -77.5 167.5 8.3 -1.5 28.5 264 265 A P + 0 0 67 0, 0.0 -1,-0.2 0, 0.0 3,-0.1 -0.339 56.5 157.2 -61.6 138.6 7.9 2.3 28.1 265 266 A V - 0 0 117 1,-0.2 2,-0.3 -3,-0.1 -2,-0.0 0.604 63.0 -7.3-125.4 -52.4 10.3 4.4 30.1 266 267 A R - 0 0 148 -220,-0.0 -7,-2.5 0, 0.0 -6,-0.2 -0.940 67.2-109.6-158.8 131.7 10.6 7.9 28.4 267 268 A S E +Q 258 0G 38 -2,-0.3 -9,-0.3 -9,-0.2 2,-0.2 -0.330 52.3 148.4 -60.2 132.6 9.4 9.6 25.2 268 269 A S E -Q 257 0G 27 -11,-2.7 -11,-2.4 -2,-0.0 2,-0.3 -0.758 41.0-108.5-147.2-163.9 12.1 10.3 22.7 269 270 A Y E +Q 256 0G 56 -13,-0.3 2,-0.3 -2,-0.2 -13,-0.2 -0.987 36.1 162.3-140.2 140.8 13.0 10.5 19.0 270 271 A G E -Q 255 0G 16 -15,-2.4 -15,-1.8 -2,-0.3 2,-0.3 -0.994 34.6-107.2-162.0 154.0 15.0 8.2 16.9 271 272 A M E +Q 254 0G 116 -2,-0.3 2,-0.3 -17,-0.2 -17,-0.2 -0.622 35.6 175.1 -87.0 145.5 15.9 7.1 13.3 272 273 A K E -Q 253 0G 57 -19,-1.5 -19,-2.0 -2,-0.3 2,-0.3 -0.949 19.5-142.0-141.8 161.0 14.7 3.8 11.8 273 274 A A + 0 0 60 -2,-0.3 -22,-0.2 -22,-0.2 2,-0.2 -0.936 44.0 99.4-125.0 151.0 14.8 2.0 8.5 274 275 A G S >> S- 0 0 3 -24,-2.6 3,-1.4 -2,-0.3 4,-0.8 -0.677 76.9 -98.8 151.2 153.7 12.0 -0.1 6.8 275 276 A T H 3> S+ 0 0 0 1,-0.3 4,-2.2 -2,-0.2 -71,-0.2 0.662 119.5 73.3 -67.2 -16.3 9.3 0.0 4.2 276 277 A S H 34 S+ 0 0 9 1,-0.2 -1,-0.3 2,-0.2 -101,-0.1 0.714 97.2 45.8 -64.6 -24.9 7.2 0.6 7.3 277 278 A M H <> S+ 0 0 2 -3,-1.4 4,-0.6 -27,-0.2 -1,-0.2 0.701 109.8 54.6 -90.4 -24.6 8.7 4.1 7.5 278 279 A A H >X S+ 0 0 0 -4,-0.8 4,-1.4 -28,-0.2 3,-0.9 0.906 100.0 59.6 -74.0 -44.6 8.1 4.7 3.7 279 280 A A H 3X S+ 0 0 0 -4,-2.2 4,-2.6 -54,-0.2 3,-0.2 0.877 100.3 54.3 -52.3 -47.6 4.4 3.9 3.9 280 281 A P H 3> S+ 0 0 0 0, 0.0 4,-2.3 0, 0.0 -1,-0.2 0.761 102.0 59.1 -64.3 -22.7 3.5 6.6 6.4 281 282 A H H <>S+ 0 0 1 -4,-2.5 5,-2.8 1,-0.2 3,-0.9 0.895 109.1 55.1 -61.0 -42.5 -9.4 18.3 -2.6 294 295 A N H ><5S+ 0 0 80 -4,-3.0 3,-1.7 1,-0.2 -1,-0.2 0.870 99.0 62.4 -54.8 -40.3 -11.7 19.2 0.3 295 296 A S H 3<5S+ 0 0 72 -4,-1.4 -1,-0.2 1,-0.3 -2,-0.2 0.724 110.9 37.8 -63.9 -24.3 -10.8 22.9 -0.1 296 297 A I T <<5S- 0 0 94 -3,-0.9 -1,-0.3 -4,-0.7 -2,-0.2 0.179 117.5-109.6-110.0 14.6 -12.3 22.9 -3.6 297 298 A G T < 5 + 0 0 69 -3,-1.7 2,-0.5 1,-0.2 -3,-0.2 0.806 65.9 152.1 63.2 33.7 -15.3 20.6 -2.8 298 299 A K < - 0 0 106 -5,-2.8 2,-0.4 -8,-0.1 -1,-0.2 -0.855 38.4-143.2-101.0 125.3 -13.9 17.7 -4.8 299 300 A T - 0 0 120 -2,-0.5 2,-0.5 -5,-0.0 -9,-0.0 -0.699 16.5-163.2 -81.0 132.1 -14.7 14.1 -3.9 300 301 A L - 0 0 29 -2,-0.4 -6,-0.0 -103,-0.1 -10,-0.0 -0.979 8.1-148.0-118.4 124.8 -11.8 11.6 -4.4 301 302 A T > - 0 0 63 -2,-0.5 4,-2.9 1,-0.1 5,-0.2 -0.476 33.4-109.8 -75.9 159.0 -12.2 7.8 -4.5 302 303 A P H > S+ 0 0 15 0, 0.0 4,-2.7 0, 0.0 5,-0.2 0.871 122.5 53.6 -56.3 -35.6 -9.3 5.8 -3.2 303 304 A S H > S+ 0 0 90 2,-0.2 4,-2.0 1,-0.2 5,-0.1 0.914 110.9 44.4 -63.3 -46.3 -8.6 4.7 -6.8 304 305 A E H > S+ 0 0 86 2,-0.2 4,-1.9 1,-0.2 -1,-0.2 0.904 115.0 48.1 -64.1 -44.6 -8.5 8.4 -7.9 305 306 A L H X S+ 0 0 4 -4,-2.9 4,-2.2 1,-0.2 -2,-0.2 0.940 111.4 51.2 -59.9 -48.2 -6.3 9.4 -4.9 306 307 A S H X S+ 0 0 26 -4,-2.7 4,-2.3 -5,-0.2 5,-0.2 0.875 108.9 51.2 -55.3 -43.4 -4.0 6.4 -5.6 307 308 A D H X S+ 0 0 86 -4,-2.0 4,-2.8 2,-0.2 -1,-0.2 0.867 108.1 51.6 -66.5 -38.3 -3.6 7.4 -9.3 308 309 A I H X S+ 0 0 8 -4,-1.9 4,-1.6 2,-0.2 -2,-0.2 0.946 111.5 47.8 -59.5 -49.8 -2.7 11.0 -8.3 309 310 A L H < S+ 0 0 0 -4,-2.2 21,-0.3 1,-0.2 -2,-0.2 0.876 118.8 38.7 -61.6 -44.0 -0.0 9.8 -5.9 310 311 A V H >< S+ 0 0 39 -4,-2.3 3,-0.9 1,-0.2 -1,-0.2 0.890 114.6 55.3 -70.9 -42.3 1.5 7.3 -8.5 311 312 A R H 3< S+ 0 0 140 -4,-2.8 -2,-0.2 1,-0.2 -1,-0.2 0.768 111.9 41.7 -59.0 -33.9 1.0 9.7 -11.5 312 313 A T T 3< S+ 0 0 22 -4,-1.6 -1,-0.2 -5,-0.1 21,-0.2 0.252 78.9 137.4-111.0 9.6 2.9 12.6 -9.9 313 314 A T < - 0 0 14 -3,-0.9 16,-0.2 -4,-0.2 2,-0.2 -0.118 51.5-118.6 -56.9 152.5 6.0 10.9 -8.3 314 315 A S B -K 328 0A 19 14,-3.3 14,-2.4 1,-0.1 -1,-0.1 -0.482 40.6 -81.7 -88.4 167.3 9.4 12.5 -8.6 315 316 A R - 0 0 152 12,-0.2 -1,-0.1 -2,-0.2 12,-0.1 -0.325 34.7-124.0 -74.7 146.5 12.4 10.8 -10.3 316 317 A F - 0 0 23 2,-0.2 2,-1.5 10,-0.2 -83,-0.2 -0.327 45.4 -86.9 -70.1 164.9 14.7 8.2 -8.8 317 318 A N S S- 0 0 62 -85,-2.5 2,-0.3 2,-0.1 -1,-0.1 -0.673 83.3 -66.8 -74.1 92.4 18.4 8.9 -8.8 318 319 A G S S+ 0 0 67 -2,-1.5 2,-0.3 -85,-0.1 -2,-0.2 -0.438 106.1 0.1 61.9-117.3 19.1 7.4 -12.2 319 320 A R - 0 0 186 -2,-0.3 2,-0.2 2,-0.0 -2,-0.1 -0.820 59.3-145.0-118.5 141.6 18.5 3.7 -12.3 320 321 A L - 0 0 32 -2,-0.3 3,-0.1 -87,-0.1 -87,-0.0 -0.649 19.2-131.6 -98.9 157.3 17.4 1.1 -9.7 321 322 A D S S+ 0 0 100 -2,-0.2 2,-0.3 1,-0.2 -1,-0.1 0.747 95.3 18.3 -75.3 -26.3 18.5 -2.6 -9.3 322 323 A R S S- 0 0 126 -83,-0.1 -1,-0.2 -81,-0.0 -88,-0.1 -0.977 98.3 -83.6-144.2 153.0 14.9 -3.7 -8.9 323 324 A G + 0 0 43 -2,-0.3 -82,-2.4 1,-0.1 3,-0.1 -0.333 40.4 171.3 -62.0 132.4 11.5 -2.1 -9.8 324 325 A L - 0 0 2 1,-0.6 3,-0.4 -84,-0.2 -98,-0.3 -0.110 50.4 -94.6-135.8 35.9 10.1 0.2 -7.1 325 326 A G - 0 0 32 -81,-0.4 -1,-0.6 -84,-0.3 -79,-0.3 -0.367 68.3 -39.3 80.7-161.2 7.1 1.8 -8.8 326 327 A S S S- 0 0 36 -81,-2.1 2,-0.3 1,-0.2 -1,-0.2 0.641 101.8 -71.6 -76.6 -19.9 6.8 5.1 -10.7 327 328 A G S S- 0 0 0 -3,-0.4 -80,-2.4 -12,-0.1 2,-0.5 -0.985 71.4 -34.6 157.3-166.2 9.0 7.2 -8.5 328 329 A I B -jK 247 314A 0 -14,-2.4 -14,-3.3 -2,-0.3 -80,-0.2 -0.813 69.8-100.8 -91.5 130.5 9.3 8.9 -5.1 329 330 A V - 0 0 0 -82,-2.8 2,-0.5 -2,-0.5 -16,-0.1 -0.238 37.6-159.6 -50.7 133.4 6.0 10.3 -3.8 330 331 A D > - 0 0 14 -21,-0.3 4,-2.4 1,-0.1 -310,-0.2 -0.927 12.2-169.4-126.5 102.2 5.9 14.0 -4.4 331 332 A A H > S+ 0 0 0 -312,-2.7 4,-2.2 -2,-0.5 5,-0.2 0.835 87.3 51.4 -60.4 -37.8 3.4 16.0 -2.2 332 333 A N H > S+ 0 0 43 -313,-0.4 4,-2.4 2,-0.2 -1,-0.2 0.946 114.1 41.6 -68.2 -48.9 3.8 19.2 -4.1 333 334 A A H > S+ 0 0 28 2,-0.2 4,-1.8 1,-0.2 -2,-0.2 0.860 113.8 54.5 -64.8 -38.3 3.2 17.7 -7.6 334 335 A A H X S+ 0 0 0 -4,-2.4 4,-1.2 2,-0.2 -2,-0.2 0.923 111.1 43.8 -62.7 -48.2 0.3 15.5 -6.1 335 336 A V H X S+ 0 0 0 -4,-2.2 4,-2.3 1,-0.2 5,-0.3 0.883 109.7 57.1 -63.7 -42.3 -1.5 18.6 -4.7 336 337 A N H X S+ 0 0 74 -4,-2.4 4,-1.5 1,-0.2 -1,-0.2 0.870 103.7 55.5 -53.9 -38.7 -0.8 20.5 -8.0 337 338 A A H < S+ 0 0 35 -4,-1.8 -1,-0.2 1,-0.2 -2,-0.2 0.890 111.4 41.7 -62.9 -41.1 -2.7 17.7 -9.7 338 339 A V H < S+ 0 0 21 -4,-1.2 -2,-0.2 -3,-0.2 -1,-0.2 0.838 114.8 48.7 -78.1 -34.2 -5.8 18.0 -7.6 339 340 A L H < 0 0 43 -4,-2.3 -1,-0.2 1,-0.1 -2,-0.2 0.723 360.0 360.0 -79.9 -22.4 -6.0 21.8 -7.6 340 341 A G < 0 0 107 -4,-1.5 -3,-0.1 -5,-0.3 -4,-0.1 0.303 360.0 360.0 72.0 360.0 -5.5 22.0 -11.3