==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=13-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 11-AUG-04 1U9X . COMPND 2 MOLECULE: CATHEPSIN K; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR S.W.COWAN-JACOB . 216 1 3 3 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 10267.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 132 61.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 5 2.3 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 41 19.0 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 17 7.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 20 9.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 41 19.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 4 1.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 0 1 0 0 2 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 4 2 0 1 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 0 A R 0 0 151 0, 0.0 3,-0.1 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 130.8 29.9 25.0 5.2 2 1 A A - 0 0 34 1,-0.1 122,-0.1 2,-0.1 121,-0.0 -0.522 360.0-104.8 -66.8 135.1 33.5 25.4 4.1 3 2 A P - 0 0 66 0, 0.0 -1,-0.1 0, 0.0 3,-0.1 -0.111 19.0-116.2 -60.2 158.9 34.0 29.1 3.0 4 3 A D S S+ 0 0 133 1,-0.2 2,-0.3 -3,-0.1 -2,-0.1 0.777 98.2 20.2 -64.5 -31.1 34.2 30.1 -0.7 5 4 A S + 0 0 69 166,-0.1 2,-0.3 164,-0.0 166,-0.2 -0.993 60.1 175.9-144.0 144.7 37.8 31.3 -0.2 6 5 A V E +A 170 0A 19 164,-2.1 164,-2.2 -2,-0.3 2,-0.3 -0.974 1.4 178.8-149.2 131.7 40.6 30.8 2.3 7 6 A D E > -A 169 0A 24 -2,-0.3 3,-1.0 162,-0.2 4,-0.5 -0.822 9.4-168.8-138.3 98.8 44.1 32.2 2.2 8 7 A Y T 3 >S+ 0 0 12 160,-2.7 5,-1.9 -2,-0.3 3,-0.5 0.662 82.5 71.6 -63.6 -14.5 46.3 31.2 5.1 9 8 A R T > 5S+ 0 0 95 159,-0.3 3,-1.7 1,-0.2 -1,-0.2 0.940 95.5 54.9 -64.6 -40.9 49.0 33.7 4.1 10 9 A K T < 5S+ 0 0 172 -3,-1.0 -1,-0.2 1,-0.3 -2,-0.2 0.708 106.5 51.8 -62.5 -21.9 46.6 36.5 5.2 11 10 A K T 3 5S- 0 0 132 -4,-0.5 -1,-0.3 -3,-0.5 -2,-0.2 0.324 115.1-111.6 -96.8 3.1 46.2 34.8 8.7 12 11 A G T < 5S+ 0 0 30 -3,-1.7 -3,-0.2 -4,-0.2 -2,-0.1 0.815 82.5 121.0 74.2 29.5 50.0 34.6 9.4 13 12 A Y < + 0 0 42 -5,-1.9 2,-0.5 155,-0.1 27,-0.2 0.409 56.7 76.1-102.0 -2.0 50.2 30.7 9.2 14 13 A V - 0 0 21 -6,-0.4 3,-0.1 -5,-0.2 -2,-0.1 -0.947 68.0-145.0-121.8 121.8 52.7 30.6 6.3 15 14 A T - 0 0 3 -2,-0.5 3,-0.1 1,-0.2 -2,-0.1 -0.207 43.3 -72.8 -75.0 166.9 56.4 31.2 6.5 16 15 A P - 0 0 88 0, 0.0 -1,-0.2 0, 0.0 2,-0.1 -0.194 60.1 -88.6 -58.6 156.4 58.4 32.9 3.7 17 16 A V - 0 0 20 175,-0.2 170,-0.3 -3,-0.1 2,-0.2 -0.383 46.9-156.1 -67.8 136.7 59.1 31.0 0.5 18 17 A K - 0 0 52 165,-0.4 168,-2.7 168,-0.2 2,-0.5 -0.644 11.6-130.4-111.5 170.3 62.3 29.0 0.6 19 18 A N B -I 185 0B 92 166,-0.3 166,-0.2 -2,-0.2 165,-0.0 -0.990 4.7-157.6-122.9 122.3 64.6 27.6 -2.1 20 19 A Q > - 0 0 14 164,-2.5 3,-1.0 -2,-0.5 5,-0.1 0.607 30.6-158.8 -76.8 -5.8 65.6 24.0 -1.9 21 20 A G T 3 - 0 0 44 1,-0.2 -1,-0.2 163,-0.2 71,-0.1 -0.419 58.3 -18.1 70.2-142.5 68.7 24.7 -4.0 22 21 A Q T 3 S+ 0 0 198 70,-0.2 2,-0.4 -2,-0.1 -1,-0.2 0.160 115.3 95.6 -87.0 16.7 70.4 21.8 -5.9 23 22 A a S < S- 0 0 4 -3,-1.0 2,-1.9 70,-0.1 42,-0.1 -0.905 73.1-136.9-116.6 136.4 68.6 19.2 -3.8 24 23 A G B +j 65 0C 30 40,-1.5 42,-0.6 -2,-0.4 3,-0.3 -0.412 60.6 130.6 -85.5 62.4 65.4 17.3 -4.6 25 24 A S >> + 0 0 0 -2,-1.9 4,-1.7 1,-0.2 3,-1.4 0.035 15.8 128.2-104.5 27.5 64.1 17.8 -1.1 26 25 A C H 3> S+ 0 0 16 1,-0.3 4,-2.9 2,-0.2 5,-0.2 0.845 70.4 59.0 -49.8 -40.5 60.7 19.1 -2.0 27 26 A W H 3> S+ 0 0 0 -3,-0.3 4,-1.9 1,-0.2 -1,-0.3 0.823 104.8 51.1 -59.7 -33.9 59.0 16.5 0.2 28 27 A A H <> S+ 0 0 0 -3,-1.4 4,-2.5 2,-0.2 -1,-0.2 0.913 112.3 45.0 -70.4 -43.6 60.9 17.9 3.2 29 28 A F H X S+ 0 0 20 -4,-1.7 4,-2.2 2,-0.2 -2,-0.2 0.908 113.1 50.1 -67.3 -42.2 59.8 21.5 2.4 30 29 A S H X S+ 0 0 3 -4,-2.9 4,-1.5 -5,-0.2 -1,-0.2 0.910 112.4 49.8 -60.3 -44.2 56.2 20.5 1.9 31 30 A S H X S+ 0 0 0 -4,-1.9 4,-2.1 -5,-0.2 -2,-0.2 0.934 111.4 45.0 -63.4 -51.2 56.3 18.6 5.2 32 31 A V H X S+ 0 0 5 -4,-2.5 4,-3.0 1,-0.2 -1,-0.2 0.877 108.5 58.7 -66.6 -31.1 57.7 21.4 7.3 33 32 A G H X S+ 0 0 4 -4,-2.2 4,-1.7 1,-0.2 -1,-0.2 0.907 108.3 45.5 -61.3 -38.9 55.3 23.9 5.7 34 33 A A H X S+ 0 0 0 -4,-1.5 4,-1.8 1,-0.2 -1,-0.2 0.900 114.1 48.3 -71.2 -37.0 52.4 21.8 6.9 35 34 A L H X S+ 0 0 0 -4,-2.1 4,-2.4 1,-0.2 -2,-0.2 0.867 107.1 57.5 -70.1 -33.3 54.0 21.4 10.4 36 35 A E H X S+ 0 0 6 -4,-3.0 4,-2.0 1,-0.2 -1,-0.2 0.900 106.3 48.9 -64.0 -38.4 54.6 25.2 10.4 37 36 A G H X S+ 0 0 0 -4,-1.7 4,-2.5 1,-0.2 -1,-0.2 0.912 112.1 47.0 -67.2 -42.4 50.9 25.8 10.0 38 37 A Q H X S+ 0 0 22 -4,-1.8 4,-2.7 2,-0.2 -1,-0.2 0.873 110.2 53.5 -68.2 -34.7 49.8 23.4 12.7 39 38 A L H X>S+ 0 0 9 -4,-2.4 4,-3.0 2,-0.2 5,-0.5 0.925 111.3 46.5 -64.6 -41.2 52.4 24.9 15.1 40 39 A K H X5S+ 0 0 54 -4,-2.0 4,-2.1 -5,-0.2 -2,-0.2 0.934 112.6 49.7 -65.4 -44.3 51.0 28.3 14.4 41 40 A K H <5S+ 0 0 92 -4,-2.5 -2,-0.2 1,-0.2 -1,-0.2 0.927 118.4 39.5 -59.7 -45.0 47.4 27.1 14.9 42 41 A K H <5S+ 0 0 141 -4,-2.7 -2,-0.2 -5,-0.2 -1,-0.2 0.877 132.7 16.5 -75.2 -39.1 48.3 25.4 18.2 43 42 A T H <5S- 0 0 65 -4,-3.0 -3,-0.2 2,-0.2 -2,-0.2 0.599 90.4-119.2-115.0 -15.7 50.7 27.9 19.8 44 43 A G S < + 0 0 0 33,-2.3 4,-0.9 1,-0.2 33,-0.2 -0.694 35.5 172.3 -98.6 104.3 63.9 22.3 9.6 51 50 A P H > S+ 0 0 4 0, 0.0 4,-2.4 0, 0.0 -1,-0.2 0.802 86.0 61.6 -70.5 -25.5 63.8 20.5 6.3 52 51 A Q H > S+ 0 0 1 36,-0.4 4,-2.8 1,-0.2 5,-0.3 0.881 96.8 58.7 -65.8 -36.5 67.5 19.6 6.7 53 52 A N H > S+ 0 0 7 35,-0.4 4,-1.4 1,-0.2 -1,-0.2 0.888 111.0 42.6 -58.2 -39.5 66.6 17.6 9.9 54 53 A L H X S+ 0 0 0 -4,-0.9 4,-2.9 2,-0.2 -2,-0.2 0.905 112.0 52.3 -75.3 -42.6 64.3 15.5 7.7 55 54 A V H < S+ 0 0 7 -4,-2.4 8,-0.2 1,-0.2 -2,-0.2 0.956 117.6 38.6 -56.9 -50.2 66.7 15.2 4.7 56 55 A D H < S+ 0 0 19 -4,-2.8 41,-0.2 1,-0.2 -1,-0.2 0.760 127.4 33.5 -71.7 -29.3 69.5 13.9 7.0 57 56 A b H < S+ 0 0 12 -4,-1.4 2,-1.7 -5,-0.3 -2,-0.2 0.695 84.2 90.7-109.4 -17.7 67.2 11.8 9.2 58 57 A V >< - 0 0 7 -4,-2.9 3,-2.1 1,-0.2 5,-0.4 -0.600 49.5-179.4 -82.0 89.5 64.3 10.2 7.5 59 58 A S T 3 S+ 0 0 113 -2,-1.7 -1,-0.2 1,-0.3 -4,-0.0 0.776 76.6 63.6 -60.0 -27.0 66.0 7.0 6.5 60 59 A E T 3 S+ 0 0 157 -3,-0.1 -1,-0.3 11,-0.1 2,-0.2 0.670 99.9 64.2 -73.8 -13.7 62.9 5.7 4.8 61 60 A N S < S- 0 0 14 -3,-2.1 6,-0.2 -7,-0.2 5,-0.0 -0.543 88.6-119.2-100.9 173.9 63.2 8.6 2.3 62 61 A D > - 0 0 112 4,-2.1 3,-2.7 1,-0.3 5,-0.1 -0.086 35.4-136.8-107.5 37.2 66.0 9.2 -0.3 63 62 A G T > S+ 0 0 3 -5,-0.4 3,-1.2 1,-0.3 -1,-0.3 -0.247 85.3 1.7 54.7-121.5 67.3 12.6 0.9 64 63 A a T 3 S+ 0 0 28 1,-0.3 -40,-1.5 -39,-0.1 -1,-0.3 0.420 127.5 72.2 -77.3 2.3 68.0 14.9 -2.1 65 64 A G B < S-j 24 0C 54 -3,-2.7 -1,-0.3 1,-0.4 -2,-0.2 0.401 112.4 -88.1 -98.9 4.1 66.7 12.1 -4.3 66 65 A G < - 0 0 22 -3,-1.2 -4,-2.1 -42,-0.6 -1,-0.4 -0.405 48.2-179.7 113.6 169.0 63.0 12.4 -3.3 67 66 A G - 0 0 30 -6,-0.2 2,-0.4 -2,-0.1 -6,-0.1 -0.985 29.6 -82.8 175.2-179.4 60.7 11.1 -0.6 68 67 A Y > - 0 0 135 -2,-0.3 4,-1.2 1,-0.1 3,-0.2 -0.914 20.3-140.8-113.9 140.5 57.1 10.9 0.8 69 68 A M H > S+ 0 0 7 -2,-0.4 4,-2.3 1,-0.2 5,-0.2 0.877 102.4 59.0 -64.0 -36.9 55.6 13.5 3.2 70 69 A T H > S+ 0 0 26 1,-0.2 4,-2.7 2,-0.2 -1,-0.2 0.877 102.5 53.7 -60.9 -36.2 53.9 10.7 5.3 71 70 A N H > S+ 0 0 34 -3,-0.2 4,-2.1 1,-0.2 -1,-0.2 0.863 109.3 50.1 -64.8 -35.6 57.3 9.2 6.0 72 71 A A H X S+ 0 0 0 -4,-1.2 4,-2.3 -3,-0.2 -2,-0.2 0.882 110.3 47.0 -71.0 -40.5 58.4 12.6 7.3 73 72 A F H X S+ 0 0 0 -4,-2.3 4,-2.2 2,-0.2 -2,-0.2 0.916 112.0 52.3 -68.0 -39.2 55.4 13.1 9.5 74 73 A Q H X S+ 0 0 98 -4,-2.7 4,-2.7 -5,-0.2 5,-0.2 0.929 108.8 50.4 -61.3 -43.5 55.9 9.5 10.8 75 74 A Y H X S+ 0 0 49 -4,-2.1 4,-3.2 2,-0.2 6,-0.2 0.955 109.0 50.4 -58.9 -53.7 59.5 10.3 11.6 76 75 A V H <>S+ 0 0 0 -4,-2.3 5,-2.1 1,-0.2 32,-0.3 0.899 113.2 47.6 -52.1 -42.9 58.7 13.5 13.5 77 76 A Q H ><5S+ 0 0 79 -4,-2.2 3,-0.9 3,-0.2 -2,-0.2 0.956 117.2 39.8 -64.2 -50.6 56.1 11.6 15.6 78 77 A K H 3<5S+ 0 0 79 -4,-2.7 -2,-0.2 1,-0.2 -1,-0.2 0.862 116.9 50.6 -68.7 -33.0 58.4 8.6 16.4 79 78 A N T 3<5S- 0 0 63 -4,-3.2 -1,-0.2 -5,-0.2 -2,-0.2 0.409 109.4-125.2 -83.5 -1.3 61.4 10.8 16.9 80 79 A R T < 5S- 0 0 181 -3,-0.9 2,-0.2 -4,-0.3 -3,-0.2 0.778 72.2 -0.5 62.4 30.6 59.4 13.1 19.3 81 80 A G < - 0 0 0 -5,-2.1 2,-0.3 -6,-0.2 26,-0.2 -0.758 59.8-117.6 145.3 166.9 60.1 16.3 17.5 82 81 A I E -L 106 0E 0 24,-1.6 23,-2.9 -2,-0.2 24,-1.3 -0.956 34.6-118.5-135.6 147.5 61.7 18.3 14.6 83 82 A D E -L 104 0E 2 -2,-0.3 -33,-2.3 21,-0.3 21,-0.2 -0.357 27.2-105.9 -84.5 167.3 64.2 21.0 15.1 84 83 A S B > -K 49 0D 17 19,-1.3 4,-1.8 -35,-0.3 -35,-0.3 -0.498 30.4-112.0 -84.2 163.5 63.8 24.7 14.1 85 84 A E T 4 S+ 0 0 42 -37,-3.0 -36,-0.1 1,-0.2 -1,-0.1 0.891 118.8 59.1 -62.4 -37.2 65.7 26.0 11.0 86 85 A D T 4 S+ 0 0 145 -38,-0.5 -1,-0.2 1,-0.2 -37,-0.1 0.882 110.8 39.7 -59.0 -40.0 67.8 28.1 13.4 87 86 A A T 4 S+ 0 0 36 1,-0.3 -1,-0.2 16,-0.2 -2,-0.2 0.727 131.8 24.0 -83.4 -24.0 69.0 25.0 15.2 88 87 A Y S < S- 0 0 7 -4,-1.8 -36,-0.4 15,-0.1 -35,-0.4 -0.629 87.7-158.8-143.7 80.9 69.5 22.7 12.2 89 88 A P - 0 0 73 0, 0.0 2,-0.4 0, 0.0 -3,-0.1 -0.131 22.4-102.6 -69.3 155.9 70.0 24.9 9.1 90 89 A Y + 0 0 45 1,-0.1 -5,-0.0 2,-0.1 -40,-0.0 -0.582 39.5 166.3 -77.3 128.4 69.5 23.9 5.5 91 90 A V - 0 0 77 -2,-0.4 -1,-0.1 2,-0.2 3,-0.1 0.485 44.6-125.0-118.6 -9.0 72.6 23.1 3.6 92 91 A G S S+ 0 0 17 1,-0.2 2,-0.3 -71,-0.1 -70,-0.2 0.792 78.9 75.9 73.5 29.3 71.1 21.5 0.5 93 92 A Q S S- 0 0 112 -70,-0.1 -2,-0.2 -72,-0.0 2,-0.2 -0.931 87.7 -92.4-160.5 154.0 72.9 18.1 0.5 94 93 A E + 0 0 100 -2,-0.3 2,-0.2 -39,-0.1 -38,-0.1 -0.514 50.1 163.9 -77.8 140.5 72.5 15.1 2.6 95 94 A E - 0 0 81 -2,-0.2 3,-0.0 -43,-0.2 -1,-0.0 -0.780 44.9 -56.9-140.9-177.0 74.7 14.7 5.7 96 95 A S - 0 0 95 -2,-0.2 2,-0.9 1,-0.1 -40,-0.1 -0.316 61.0-101.6 -64.7 150.9 74.8 12.7 8.9 97 96 A b - 0 0 71 -41,-0.2 2,-0.2 -42,-0.1 -1,-0.1 -0.648 45.9-155.0 -76.1 105.7 71.7 12.9 11.1 98 97 A M - 0 0 83 -2,-0.9 2,-0.5 -3,-0.0 -42,-0.0 -0.574 6.1-142.3 -87.8 149.9 72.8 15.4 13.8 99 98 A Y - 0 0 176 -2,-0.2 3,-0.0 3,-0.0 -2,-0.0 -0.948 10.7-166.6-111.2 125.0 71.4 15.4 17.3 100 99 A N > - 0 0 45 -2,-0.5 3,-1.9 1,-0.1 4,-0.4 -0.940 14.7-149.4-112.4 108.7 70.9 18.8 18.9 101 100 A P T 3 S+ 0 0 100 0, 0.0 -1,-0.1 0, 0.0 3,-0.1 0.735 98.2 24.7 -48.5 -25.4 70.2 18.5 22.6 102 101 A T T 3 S+ 0 0 138 1,-0.1 -15,-0.0 -15,-0.1 -3,-0.0 0.097 91.5 101.0-129.5 26.5 68.0 21.7 22.5 103 102 A G < + 0 0 5 -3,-1.9 -19,-1.3 -16,-0.1 -16,-0.2 0.696 44.7 123.7 -84.6 -17.0 66.8 21.9 18.9 104 103 A K E +L 83 0E 82 -4,-0.4 -21,-0.3 -21,-0.2 3,-0.1 -0.225 20.7 156.6 -54.7 116.7 63.3 20.6 19.3 105 104 A A E + 0 0 28 -23,-2.9 2,-0.3 1,-0.3 -22,-0.2 0.589 59.3 13.5-118.0 -20.1 60.7 23.1 18.1 106 105 A A E -L 82 0E 7 -24,-1.3 -24,-1.6 -30,-0.0 -1,-0.3 -0.988 57.6-147.8-155.5 156.9 57.5 21.1 17.3 107 106 A K - 0 0 131 -2,-0.3 2,-0.4 -26,-0.2 -30,-0.1 -0.833 8.3-149.4-122.9 164.6 56.0 17.7 17.8 108 107 A C - 0 0 9 -32,-0.3 108,-0.2 -2,-0.3 -28,-0.2 -0.994 8.3-166.2-135.3 139.3 53.7 15.6 15.6 109 108 A R - 0 0 147 106,-3.7 2,-0.3 -2,-0.4 107,-0.2 0.209 63.8 -67.9-110.2 14.2 51.1 13.1 16.8 110 109 A G E -B 215 0A 5 105,-0.5 105,-2.8 -37,-0.2 -1,-0.3 -0.916 52.6-104.8 134.8-163.8 50.4 11.5 13.5 111 110 A Y E -B 214 0A 57 103,-0.3 2,-0.4 -2,-0.3 -41,-0.0 -0.971 10.9-139.8-158.0 167.4 48.9 12.3 10.1 112 111 A R E -B 213 0A 124 101,-2.1 101,-1.9 -2,-0.3 2,-0.3 -0.985 14.7-140.0-134.1 146.1 45.8 11.9 8.0 113 112 A E E -B 212 0A 115 -2,-0.4 99,-0.3 99,-0.2 3,-0.0 -0.818 19.5-123.2-104.4 147.4 45.6 11.3 4.2 114 113 A I - 0 0 16 97,-2.7 97,-0.3 -2,-0.3 3,-0.1 -0.692 45.2 -89.9 -85.6 139.1 42.9 12.9 2.0 115 114 A P > - 0 0 78 0, 0.0 3,-2.0 0, 0.0 7,-0.1 -0.261 59.8 -88.7 -50.1 133.7 40.8 10.4 0.1 116 115 A E T 3 S- 0 0 162 1,-0.3 93,-0.3 93,-0.1 3,-0.1 -0.188 103.6 -5.1 -51.6 122.7 42.5 9.7 -3.3 117 116 A G T 3 S+ 0 0 33 91,-2.1 2,-1.0 1,-0.2 -1,-0.3 0.521 91.8 133.0 73.1 7.0 41.4 12.2 -6.0 118 117 A N <> + 0 0 71 -3,-2.0 4,-1.6 90,-0.6 -1,-0.2 -0.735 27.0 176.5 -98.3 98.5 38.7 13.9 -3.9 119 118 A E H > S+ 0 0 14 -2,-1.0 4,-2.5 1,-0.2 -1,-0.2 0.808 80.9 57.4 -67.9 -31.4 39.2 17.7 -4.4 120 119 A K H > S+ 0 0 42 2,-0.2 4,-2.1 1,-0.2 -1,-0.2 0.903 107.9 46.9 -66.6 -41.5 36.1 18.4 -2.3 121 120 A A H > S+ 0 0 22 2,-0.2 4,-2.3 1,-0.2 -2,-0.2 0.860 111.7 52.3 -67.0 -31.8 37.6 16.5 0.6 122 121 A L H X S+ 0 0 0 -4,-1.6 4,-2.7 2,-0.2 -2,-0.2 0.930 107.6 51.6 -69.2 -40.8 40.8 18.4 0.0 123 122 A K H X S+ 0 0 50 -4,-2.5 4,-2.6 1,-0.2 -2,-0.2 0.924 110.9 47.8 -59.5 -46.6 39.0 21.7 0.1 124 123 A R H X S+ 0 0 152 -4,-2.1 4,-3.0 1,-0.2 5,-0.3 0.910 110.7 51.0 -63.1 -42.5 37.4 20.8 3.5 125 124 A A H X>S+ 0 0 10 -4,-2.3 4,-2.9 2,-0.2 5,-1.1 0.934 111.1 48.4 -62.0 -45.6 40.7 19.7 5.0 126 125 A V H <5S+ 0 0 0 -4,-2.7 4,-0.3 1,-0.2 -2,-0.2 0.954 113.7 48.0 -60.2 -44.5 42.3 23.0 3.9 127 126 A A H <5S+ 0 0 20 -4,-2.6 -2,-0.2 -5,-0.2 -1,-0.2 0.925 123.4 30.0 -62.7 -45.0 39.4 25.0 5.4 128 127 A R H <5S+ 0 0 120 -4,-3.0 -2,-0.2 -5,-0.2 -3,-0.2 0.827 131.2 28.2 -87.2 -32.2 39.3 23.1 8.7 129 128 A V T <5S- 0 0 25 -4,-2.9 -3,-0.2 -5,-0.3 -2,-0.1 0.906 98.1-124.1 -94.7 -53.0 42.9 22.1 9.3 130 129 A G < + 0 0 0 -5,-1.1 -1,-0.3 -4,-0.3 -2,-0.1 -0.931 65.9 10.2 135.0-160.2 45.1 24.6 7.6 131 130 A P - 0 0 0 0, 0.0 2,-0.4 0, 0.0 37,-0.2 -0.193 67.8-155.9 -53.3 138.9 47.9 24.1 4.9 132 131 A V E -C 167 0A 0 35,-2.1 35,-2.9 81,-0.1 2,-0.3 -0.957 15.3-121.3-123.8 138.6 48.0 20.6 3.5 133 132 A S E +CD 166 212A 0 79,-2.1 79,-2.0 -2,-0.4 2,-0.3 -0.628 39.4 175.7 -77.2 130.4 50.9 18.9 1.8 134 133 A V E -C 165 0A 0 31,-2.2 31,-2.9 -2,-0.3 2,-0.4 -0.942 22.7-140.9-135.3 159.1 50.2 17.8 -1.8 135 134 A A E +C 164 0A 7 -2,-0.3 74,-0.4 72,-0.3 75,-0.3 -0.911 24.4 173.0-118.6 148.7 52.0 16.2 -4.7 136 135 A I E -C 163 0A 0 27,-2.8 26,-1.9 -2,-0.4 27,-1.5 -0.906 42.0 -98.3-144.3 172.3 51.7 17.1 -8.3 137 136 A D + 0 0 2 68,-1.5 3,-0.2 -2,-0.3 24,-0.1 -0.884 42.4 167.4 -93.3 109.6 53.0 16.4 -11.8 138 137 A A + 0 0 2 -2,-0.8 6,-0.2 22,-0.1 -1,-0.1 0.182 41.8 106.9-108.7 15.1 55.4 19.4 -12.3 139 138 A S + 0 0 63 21,-0.3 2,-0.1 18,-0.1 -1,-0.1 0.666 50.9 101.3 -70.4 -19.8 57.1 18.1 -15.5 140 139 A L S >> S- 0 0 36 -3,-0.2 4,-2.4 1,-0.1 3,-0.9 -0.412 71.7-135.6 -73.4 142.8 55.6 20.4 -18.0 141 140 A T H 3> S+ 0 0 98 1,-0.3 4,-2.3 2,-0.2 -1,-0.1 0.873 107.5 62.0 -61.5 -34.6 57.4 23.4 -19.4 142 141 A S H 34 S+ 0 0 46 1,-0.2 -1,-0.3 2,-0.2 -3,-0.0 0.840 108.2 42.6 -62.6 -29.5 54.2 25.3 -18.9 143 142 A F H X4 S+ 0 0 1 -3,-0.9 3,-2.1 2,-0.2 -2,-0.2 0.948 111.6 52.9 -78.3 -49.0 54.5 24.7 -15.1 144 143 A Q H 3< S+ 0 0 79 -4,-2.4 46,-0.3 1,-0.3 -2,-0.2 0.811 117.1 38.6 -55.1 -34.7 58.2 25.3 -14.8 145 144 A F T 3< S+ 0 0 161 -4,-2.3 -1,-0.3 -5,-0.2 -2,-0.2 0.163 83.1 144.9-106.1 20.8 57.9 28.7 -16.5 146 145 A Y < + 0 0 19 -3,-2.1 44,-0.4 1,-0.1 3,-0.1 -0.224 13.5 164.2 -58.5 143.6 54.6 29.8 -14.9 147 146 A S - 0 0 71 1,-0.4 2,-0.3 42,-0.1 -1,-0.1 0.584 56.1 -16.9-131.0 -32.2 54.4 33.5 -14.1 148 147 A K S S+ 0 0 158 43,-0.1 -1,-0.4 48,-0.0 2,-0.1 -0.993 85.5 48.0-170.6 166.4 50.7 34.3 -13.5 149 148 A G S S- 0 0 21 -2,-0.3 2,-0.8 -3,-0.1 47,-0.7 -0.325 93.5 -43.3 91.3-174.3 47.0 33.4 -13.8 150 149 A V E -e 196 0A 34 23,-0.1 2,-0.2 -2,-0.1 47,-0.2 -0.831 65.8-131.0 -94.1 115.5 45.3 30.1 -12.9 151 150 A Y E +e 197 0A 15 45,-3.7 47,-2.8 -2,-0.8 2,-0.3 -0.461 40.1 151.3 -72.4 130.3 47.4 27.3 -14.2 152 151 A Y + 0 0 112 -2,-0.2 2,-0.4 45,-0.2 3,-0.1 -0.923 11.0 172.4-156.1 128.3 45.8 24.5 -16.2 153 152 A D > - 0 0 42 -2,-0.3 3,-2.2 1,-0.1 52,-0.2 -0.952 28.9-144.3-143.0 120.8 47.4 22.4 -19.0 154 153 A E T 3 S+ 0 0 81 -2,-0.4 -1,-0.1 1,-0.3 51,-0.1 0.735 97.9 65.3 -56.3 -23.5 45.6 19.4 -20.5 155 154 A S T 3 S+ 0 0 84 2,-0.1 -1,-0.3 -3,-0.1 -3,-0.0 0.601 71.6 118.1 -77.4 -9.0 48.9 17.6 -20.7 156 155 A c < - 0 0 20 -3,-2.2 2,-0.6 1,-0.1 49,-0.2 -0.306 59.5-141.6 -60.0 141.7 49.3 17.4 -17.0 157 156 A N > - 0 0 74 3,-0.2 3,-2.0 48,-0.2 -18,-0.1 -0.897 12.1-164.1-114.8 108.0 49.4 13.8 -15.9 158 157 A S T 3 S+ 0 0 38 -2,-0.6 3,-0.1 1,-0.3 -1,-0.1 0.553 92.2 53.9 -66.9 -7.1 47.7 13.0 -12.6 159 158 A D T 3 S+ 0 0 137 1,-0.2 2,-0.8 -3,-0.0 -1,-0.3 0.449 92.7 76.1-104.5 -1.6 49.4 9.7 -12.4 160 159 A N < + 0 0 69 -3,-2.0 2,-0.8 -23,-0.0 -21,-0.3 -0.667 62.6 176.6-109.6 76.3 52.9 11.2 -12.8 161 160 A L + 0 0 59 -2,-0.8 -24,-0.3 1,-0.1 3,-0.1 -0.699 17.5 145.9 -84.0 112.3 53.5 12.7 -9.3 162 161 A N + 0 0 71 -26,-1.9 2,-0.3 -2,-0.8 -25,-0.2 0.283 53.2 51.5-131.9 11.9 57.0 14.1 -9.3 163 162 A H E -C 136 0A 15 -27,-1.5 -27,-2.8 -137,-0.1 2,-0.4 -0.991 60.7-145.5-152.0 145.8 57.0 17.2 -7.1 164 163 A A E +C 135 0A 5 -2,-0.3 -29,-0.2 -29,-0.2 2,-0.2 -0.932 28.5 156.7-115.9 130.2 55.7 18.1 -3.6 165 164 A V E -C 134 0A 3 -31,-2.9 -31,-2.2 -2,-0.4 2,-0.4 -0.698 36.7-101.8-137.0-171.7 54.3 21.4 -2.7 166 165 A L E -CF 133 182A 5 16,-1.8 16,-3.2 -33,-0.2 2,-0.7 -0.980 14.4-147.5-126.7 126.2 52.0 23.1 -0.1 167 166 A A E +CF 132 181A 0 -35,-2.9 -35,-2.1 -2,-0.4 14,-0.2 -0.811 23.7 168.6 -88.6 114.8 48.3 24.1 -0.5 168 167 A V E - 0 0 0 12,-2.3 -160,-2.7 -2,-0.7 2,-0.3 0.309 61.1 -27.9-109.6 6.5 47.8 27.2 1.7 169 168 A G E -AF 7 180A 0 11,-0.7 11,-2.5 -162,-0.2 2,-0.3 -0.980 52.6-132.3 169.1-176.8 44.4 28.2 0.4 170 169 A Y E +AF 6 179A 2 -164,-2.2 -164,-2.1 -2,-0.3 2,-0.3 -0.961 31.8 133.3-156.8 164.0 41.9 28.2 -2.4 171 170 A G E - F 0 178A 4 7,-2.0 7,-2.3 -2,-0.3 2,-0.3 -0.890 45.7 -82.8-179.7-150.3 39.7 30.7 -4.1 172 171 A I E - F 0 177A 88 5,-0.3 2,-0.5 -2,-0.3 5,-0.3 -0.981 23.1-167.6-152.0 134.6 38.6 32.0 -7.5 173 172 A Q E > S- F 0 176A 80 3,-2.9 3,-1.5 -2,-0.3 -23,-0.1 -0.969 77.8 -19.2-128.9 114.7 40.1 34.5 -9.9 174 173 A K T 3 S- 0 0 191 -2,-0.5 -1,-0.1 1,-0.3 3,-0.1 0.929 130.6 -46.5 56.8 48.4 38.1 35.9 -12.8 175 174 A G T 3 S+ 0 0 66 1,-0.2 2,-0.6 -3,-0.1 -1,-0.3 0.415 115.6 116.3 77.8 -5.5 35.6 33.0 -12.6 176 175 A N E < -F 173 0A 77 -3,-1.5 -3,-2.9 22,-0.0 2,-0.2 -0.887 59.3-139.8-104.7 124.0 38.3 30.4 -12.4 177 176 A K E +F 172 0A 103 -2,-0.6 22,-2.4 22,-0.3 2,-0.3 -0.543 33.2 169.4 -76.2 140.2 38.5 28.3 -9.2 178 177 A H E -FG 171 198A 14 -7,-2.3 -7,-2.0 20,-0.3 2,-0.4 -0.891 36.1-122.3-145.4 174.4 42.0 27.6 -8.0 179 178 A W E -FG 170 197A 0 18,-2.2 18,-2.1 -2,-0.3 2,-0.7 -0.947 29.2-129.5-115.6 139.3 44.3 26.3 -5.2 180 179 A I E -FG 169 196A 7 -11,-2.5 -12,-2.3 -2,-0.4 -11,-0.7 -0.830 31.4-165.1 -93.7 117.9 47.0 28.6 -3.8 181 180 A I E -FG 167 195A 0 14,-2.6 14,-1.7 -2,-0.7 2,-0.6 -0.901 15.7-153.4-114.0 126.6 50.2 26.7 -3.9 182 181 A K E -FG 166 194A 18 -16,-3.2 -16,-1.8 -2,-0.5 12,-0.2 -0.837 19.9-167.2 -93.9 124.0 53.4 27.5 -2.1 183 182 A N - 0 0 4 10,-2.1 -165,-0.4 -2,-0.6 3,-0.1 -0.481 21.9-136.5-102.1 177.2 56.5 26.2 -3.9 184 183 A S S S+ 0 0 7 -20,-0.2 -164,-2.5 -2,-0.2 -163,-0.2 -0.247 73.8 102.0-129.7 43.8 60.1 25.8 -2.7 185 184 A W B S-I 19 0B 55 1,-0.4 4,-0.3 -166,-0.2 -166,-0.3 -0.115 93.3 -92.9-113.9 29.9 62.1 27.1 -5.7 186 185 A G > - 0 0 9 -168,-2.7 3,-1.2 1,-0.2 -1,-0.4 0.149 45.0 -70.7 81.9 163.1 62.8 30.5 -4.2 187 186 A E T 3 S+ 0 0 128 -170,-0.3 5,-0.3 1,-0.2 6,-0.2 0.667 124.0 64.2 -68.3 -17.3 60.9 33.8 -4.5 188 187 A N T 3 S+ 0 0 168 -3,-0.2 -1,-0.2 4,-0.2 2,-0.1 0.652 84.4 90.0 -83.6 -13.2 62.0 34.4 -8.1 189 188 A W S <> S- 0 0 29 -3,-1.2 4,-3.0 -4,-0.3 5,-0.3 -0.499 99.2 -26.9 -81.1 153.6 60.0 31.4 -9.3 190 189 A G T 4 S- 0 0 21 -44,-0.4 2,-1.0 -46,-0.3 5,-0.2 -0.073 126.3 -14.7 47.0-136.1 56.4 31.7 -10.4 191 190 A N B >4 S-H 194 0A 87 3,-2.9 3,-1.0 1,-0.2 -1,-0.2 -0.735 131.0 -43.4-101.2 85.1 54.5 34.6 -8.8 192 191 A K T 34 S- 0 0 157 -2,-1.0 -175,-0.2 -5,-0.3 -4,-0.2 0.838 121.5 -43.3 61.7 33.6 56.8 35.4 -5.9 193 192 A G T 3< S+ 0 0 0 -4,-3.0 -10,-2.1 1,-0.3 -8,-0.2 0.326 123.2 96.7 98.4 -5.6 57.3 31.7 -5.2 194 193 A Y E < -HG 191 182A 26 -3,-1.0 -3,-2.9 -5,-0.3 2,-0.3 -0.739 48.9-164.6-115.7 161.4 53.6 30.8 -5.6 195 194 A I E - G 0 181A 1 -14,-1.7 -14,-2.6 -2,-0.2 2,-0.6 -0.989 18.0-136.9-143.2 143.2 51.3 29.4 -8.3 196 195 A L E -eG 150 180A 23 -47,-0.7 -45,-3.7 -2,-0.3 2,-0.4 -0.929 27.7-164.7-100.4 123.4 47.5 29.3 -8.6 197 196 A M E -eG 151 179A 4 -18,-2.1 -18,-2.2 -2,-0.6 -45,-0.2 -0.906 29.2 -91.8-112.7 141.1 46.5 25.8 -9.9 198 197 A A E - G 0 178A 5 -47,-2.8 2,-0.4 -2,-0.4 3,-0.3 -0.180 38.6-151.6 -53.0 133.8 43.1 25.0 -11.3 199 198 A R S S+ 0 0 9 -22,-2.4 -22,-0.3 1,-0.2 -1,-0.1 -0.885 72.5 9.5-111.5 137.7 40.6 23.6 -8.8 200 199 A N S S+ 0 0 81 -2,-0.4 -1,-0.2 1,-0.1 -23,-0.1 0.925 83.9 124.7 60.4 46.0 37.7 21.2 -9.7 201 200 A K S S- 0 0 88 -3,-0.3 -1,-0.1 3,-0.0 -3,-0.1 -0.443 100.1 -72.0-125.5 49.4 39.1 20.6 -13.2 202 201 A N S S- 0 0 157 1,-0.2 4,-0.2 2,-0.1 3,-0.1 0.937 89.8 -53.2 61.8 53.6 39.2 16.9 -12.7 203 202 A N S > S- 0 0 20 1,-0.2 3,-2.1 2,-0.1 -1,-0.2 0.923 76.1-150.8 51.6 51.2 42.1 16.6 -10.3 204 203 A A G > S+ 0 0 13 1,-0.3 3,-1.3 -6,-0.2 -1,-0.2 -0.337 75.2 0.5 -58.7 130.0 44.4 18.6 -12.7 205 204 A c G 3 S- 0 0 3 1,-0.2 -68,-1.5 -52,-0.2 -1,-0.3 0.571 122.2 -78.5 66.2 11.1 48.0 17.5 -12.2 206 205 A G G X S+ 0 0 0 -3,-2.1 3,-2.4 -4,-0.2 4,-0.5 0.704 77.7 159.1 72.9 24.6 47.0 15.0 -9.6 207 206 A I T < S+ 0 0 1 -3,-1.3 -72,-0.3 1,-0.3 3,-0.3 0.776 73.9 40.9 -50.2 -32.7 46.6 17.7 -6.9 208 207 A A T 3 S+ 0 0 0 1,-0.2 -91,-2.1 -74,-0.1 -90,-0.6 0.261 93.3 87.9-103.7 13.7 44.3 15.5 -4.8 209 208 A N S < S+ 0 0 25 -3,-2.4 -1,-0.2 -74,-0.4 -2,-0.1 0.740 100.9 17.8 -85.2 -23.9 46.1 12.2 -5.2 210 209 A L S S+ 0 0 56 -4,-0.5 2,-0.3 -75,-0.3 -1,-0.2 -0.320 84.3 146.8-146.6 59.5 48.7 12.2 -2.4 211 210 A A + 0 0 2 -3,-0.4 -97,-2.7 -97,-0.3 2,-0.3 -0.783 12.9 155.9-101.4 141.0 47.6 14.8 0.1 212 211 A S E -BD 113 133A 3 -79,-2.0 -79,-2.1 -2,-0.3 -99,-0.2 -0.973 22.5-156.7-157.9 161.0 48.1 14.6 3.8 213 212 A F E -B 112 0A 32 -101,-1.9 -101,-2.1 -2,-0.3 2,-0.2 -0.986 24.8-113.8-142.9 147.5 48.4 16.8 6.9 214 213 A P E -B 111 0A 1 0, 0.0 2,-0.4 0, 0.0 -103,-0.3 -0.548 22.1-129.4 -83.2 151.1 50.0 16.2 10.3 215 214 A K E B 110 0A 65 -105,-2.8 -106,-3.7 -2,-0.2 -105,-0.5 -0.835 360.0 360.0 -97.3 134.0 48.1 15.9 13.6 216 215 A M 0 0 39 -2,-0.4 -108,-0.1 -108,-0.2 -110,-0.0 -0.919 360.0 360.0-129.0 360.0 49.4 18.1 16.4