==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=18-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 24-OCT-03 1UQZ . COMPND 2 MOLECULE: ENDOXYLANASE; . SOURCE 2 ORGANISM_SCIENTIFIC: CELLVIBRIO MIXTUS; . AUTHOR G.PELL,E.J.TAYLOR,T.M.GLOSTER,J.P.TURKENBURG,C.M.G.A.FONTES, . 348 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 15124.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 243 69.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 49 14.1 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 8 2.3 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 4 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 15 4.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 45 12.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 111 31.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 5 1.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 3 0 1 0 0 0 1 1 2 1 1 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 1 1 6 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 26 A G >> 0 0 33 0, 0.0 4,-2.4 0, 0.0 3,-0.5 0.000 360.0 360.0 360.0-171.5 27.0 31.5 21.8 2 27 A L H 3> + 0 0 1 1,-0.2 4,-2.6 2,-0.2 33,-0.1 0.892 360.0 56.9 -59.8 -45.3 24.0 29.4 20.7 3 28 A K H 34 S+ 0 0 61 32,-1.4 -1,-0.2 1,-0.2 7,-0.1 0.850 113.0 42.9 -57.6 -34.6 24.3 30.0 17.0 4 29 A S H X4 S+ 0 0 69 -3,-0.5 3,-1.5 30,-0.4 4,-0.3 0.913 110.7 52.9 -77.1 -44.8 27.9 28.7 17.1 5 30 A A H 3< S+ 0 0 32 -4,-2.4 3,-0.3 1,-0.3 -2,-0.2 0.891 119.2 38.2 -54.7 -40.2 27.2 25.7 19.4 6 31 A Y T >X S+ 0 0 0 -4,-2.6 3,-2.3 -5,-0.2 4,-1.9 0.265 80.9 117.0 -97.1 12.8 24.4 24.7 16.9 7 32 A K T <4 S+ 0 0 168 -3,-1.5 -1,-0.2 1,-0.3 -2,-0.1 0.837 77.4 46.9 -52.4 -42.7 26.2 25.6 13.7 8 33 A D T 34 S+ 0 0 150 -3,-0.3 -1,-0.3 -4,-0.3 -2,-0.1 0.494 118.5 43.6 -79.7 -3.7 26.3 22.1 12.3 9 34 A N T <4 S- 0 0 21 -3,-2.3 2,-0.3 1,-0.3 -2,-0.2 0.834 117.1 -47.4-105.4 -63.1 22.6 21.6 13.1 10 35 A F < - 0 0 10 -4,-1.9 -1,-0.3 -7,-0.1 289,-0.3 -0.984 61.9 -71.4-168.5 163.3 20.5 24.5 12.2 11 36 A L E -a 299 0A 46 287,-2.4 289,-2.5 -2,-0.3 2,-0.5 -0.337 37.7-143.5 -61.6 149.9 20.1 28.3 12.4 12 37 A I E +a 300 0A 1 287,-0.2 25,-2.5 289,-0.0 26,-1.1 -0.985 30.1 179.8-120.3 117.8 19.3 29.8 15.8 13 38 A G E -ab 301 38A 0 287,-2.5 289,-2.6 -2,-0.5 2,-0.3 -0.684 21.4-157.0-120.4 168.4 17.0 32.8 15.5 14 39 A A E -ab 302 39A 0 24,-1.5 26,-1.6 287,-0.2 2,-0.4 -0.995 22.8-124.2-142.8 140.0 15.1 35.5 17.4 15 40 A A E - b 0 40A 1 287,-2.3 2,-0.5 -2,-0.3 290,-0.2 -0.700 32.1-154.5 -74.3 129.7 12.0 37.6 16.7 16 41 A L E - b 0 41A 3 24,-2.9 26,-2.2 -2,-0.4 27,-0.4 -0.930 3.0-144.6-113.6 128.1 13.0 41.3 17.1 17 42 A N > - 0 0 37 -2,-0.5 4,-2.6 24,-0.2 5,-0.2 -0.223 36.8 -96.5 -77.2 174.0 10.5 44.1 18.0 18 43 A A H > S+ 0 0 43 1,-0.2 4,-1.0 2,-0.2 -1,-0.1 0.850 121.6 55.0 -64.0 -35.7 10.9 47.6 16.5 19 44 A T H 4>S+ 0 0 114 2,-0.2 5,-0.5 1,-0.2 3,-0.4 0.939 113.1 41.8 -63.3 -47.0 12.8 49.0 19.5 20 45 A I H >45S+ 0 0 11 1,-0.2 3,-1.8 2,-0.2 5,-0.3 0.933 111.4 54.4 -64.4 -48.2 15.4 46.3 19.3 21 46 A A H 3<5S+ 0 0 5 -4,-2.6 -1,-0.2 1,-0.3 -2,-0.2 0.678 89.5 78.2 -65.6 -14.2 15.8 46.3 15.6 22 47 A S T 3<5S- 0 0 65 -4,-1.0 -1,-0.3 -3,-0.4 -2,-0.2 0.757 97.5-134.6 -62.1 -24.6 16.4 50.1 15.7 23 48 A G T < 5S+ 0 0 22 -3,-1.8 -2,-0.1 -4,-0.3 -3,-0.1 0.506 71.9 119.6 82.6 7.4 20.0 49.2 16.8 24 49 A A < + 0 0 89 -5,-0.5 2,-0.9 1,-0.1 -4,-0.1 0.708 54.9 77.4 -76.8 -20.5 20.0 51.9 19.5 25 50 A D > - 0 0 66 -5,-0.3 4,-2.4 -6,-0.3 5,-0.2 -0.777 59.0-174.1 -97.9 98.7 20.5 49.3 22.3 26 51 A E H > S+ 0 0 135 -2,-0.9 4,-2.1 1,-0.2 -1,-0.2 0.842 82.6 57.2 -67.9 -31.1 24.2 48.4 22.3 27 52 A R H > S+ 0 0 109 1,-0.2 4,-2.3 2,-0.2 -1,-0.2 0.939 111.4 42.9 -61.5 -46.7 23.9 45.7 24.9 28 53 A L H > S+ 0 0 10 2,-0.2 4,-3.2 1,-0.2 5,-0.3 0.869 109.3 57.2 -67.8 -37.2 21.3 43.9 22.8 29 54 A N H X S+ 0 0 20 -4,-2.4 4,-2.1 2,-0.2 -1,-0.2 0.921 110.0 46.2 -58.4 -40.3 23.3 44.4 19.6 30 55 A T H X S+ 0 0 81 -4,-2.1 4,-2.0 2,-0.2 -2,-0.2 0.952 114.4 46.5 -66.6 -49.2 26.1 42.6 21.2 31 56 A L H X S+ 0 0 19 -4,-2.3 4,-2.6 1,-0.2 5,-0.3 0.922 112.9 49.0 -57.6 -49.6 24.0 39.8 22.6 32 57 A I H X S+ 0 0 0 -4,-3.2 4,-2.6 1,-0.2 -1,-0.2 0.918 110.8 49.0 -62.8 -43.1 22.1 39.3 19.3 33 58 A A H < S+ 0 0 36 -4,-2.1 -1,-0.2 -5,-0.3 -2,-0.2 0.857 116.2 45.3 -65.1 -33.9 25.3 39.1 17.2 34 59 A K H < S+ 0 0 117 -4,-2.0 -30,-0.4 -5,-0.2 -31,-0.2 0.890 124.6 28.3 -70.1 -43.7 26.8 36.6 19.6 35 60 A E H < S+ 0 0 4 -4,-2.6 -32,-1.4 -34,-0.2 2,-0.4 0.771 112.2 50.2 -97.7 -32.6 23.7 34.3 20.0 36 61 A F < - 0 0 3 -4,-2.6 -23,-0.2 -5,-0.3 -1,-0.1 -0.883 35.9-179.7-122.8 141.9 21.6 34.4 16.8 37 62 A N S S+ 0 0 36 -25,-2.5 38,-2.4 -2,-0.4 2,-0.3 0.246 78.1 49.0-117.2 10.7 22.2 34.0 13.1 38 63 A S E -bc 13 75A 0 -26,-1.1 -24,-1.5 36,-0.2 2,-0.3 -0.985 62.4-172.3-141.9 149.3 18.6 34.5 12.0 39 64 A I E -bc 14 76A 0 36,-2.4 38,-2.4 -2,-0.3 -24,-0.2 -0.985 7.8-163.7-141.6 155.6 16.0 37.1 12.9 40 65 A T E -b 15 0A 2 -26,-1.6 -24,-2.9 -2,-0.3 2,-0.4 -0.991 31.5-112.9-133.8 139.6 12.3 37.6 12.2 41 66 A P E -b 16 0A 0 0, 0.0 -24,-0.2 0, 0.0 4,-0.2 -0.625 21.5-148.9 -76.4 127.2 10.4 40.9 12.6 42 67 A E S S- 0 0 16 -26,-2.2 -25,-0.2 -2,-0.4 -27,-0.1 0.869 78.8 -24.1 -66.7 -36.3 7.9 40.5 15.5 43 68 A N S > S+ 0 0 55 -27,-0.4 3,-2.0 -3,-0.0 6,-0.2 0.562 108.6 92.8-142.1 -26.1 5.3 42.9 14.0 44 69 A C T 3 S+ 0 0 14 1,-0.3 18,-0.3 5,-0.1 17,-0.1 0.619 89.5 48.5 -70.8 -15.3 6.5 45.5 11.6 45 70 A M T 3 S+ 0 0 0 34,-0.5 -1,-0.3 -4,-0.2 2,-0.2 0.350 81.9 115.7-101.3 6.2 6.0 43.6 8.3 46 71 A K S X> S- 0 0 12 -3,-2.0 4,-2.9 1,-0.1 3,-1.8 -0.565 76.7-118.9 -72.1 141.1 2.4 42.6 9.2 47 72 A W H 3> S+ 0 0 14 33,-0.5 4,-2.1 1,-0.3 40,-0.2 0.861 111.2 46.1 -48.1 -51.2 -0.1 44.1 6.8 48 73 A G H 34 S+ 0 0 20 38,-2.6 -1,-0.3 37,-0.3 39,-0.2 0.548 117.4 44.6 -72.5 -11.5 -2.1 46.1 9.4 49 74 A V H <4 S+ 0 0 73 -3,-1.8 -2,-0.2 37,-0.4 -1,-0.2 0.799 116.5 42.6 -98.5 -43.3 1.1 47.4 11.0 50 75 A L H < S+ 0 0 4 -4,-2.9 8,-2.2 -7,-0.2 2,-0.3 0.801 121.8 39.5 -71.1 -31.2 3.0 48.3 7.8 51 76 A R B < S-I 57 0B 13 -4,-2.1 6,-0.2 -5,-0.4 37,-0.1 -0.908 77.1-129.9-125.9 148.3 -0.0 49.9 6.2 52 77 A D > - 0 0 62 4,-2.2 3,-2.2 -2,-0.3 36,-0.1 -0.228 42.9 -88.5 -87.1 179.8 -2.9 52.0 7.4 53 78 A A T 3 S+ 0 0 44 1,-0.3 -1,-0.1 2,-0.1 -5,-0.0 0.685 128.2 56.2 -68.7 -17.1 -6.6 51.4 6.8 54 79 A Q T 3 S- 0 0 156 2,-0.1 -1,-0.3 37,-0.0 -3,-0.0 0.375 121.4-107.0 -91.4 5.0 -6.4 53.4 3.6 55 80 A G < + 0 0 18 -3,-2.2 2,-0.2 1,-0.3 -2,-0.1 0.511 69.1 150.2 86.1 5.3 -3.6 51.1 2.3 56 81 A Q - 0 0 105 1,-0.1 -4,-2.2 -5,-0.0 2,-0.3 -0.482 37.8-134.4 -78.9 141.7 -0.9 53.8 2.7 57 82 A W B -I 51 0B 64 -6,-0.2 2,-0.4 -2,-0.2 -6,-0.2 -0.735 20.3-174.1-103.1 142.4 2.6 52.4 3.5 58 83 A N - 0 0 113 -8,-2.2 4,-0.3 -2,-0.3 3,-0.3 -0.900 1.9-176.2-134.9 111.2 5.1 53.5 6.1 59 84 A W > + 0 0 40 -2,-0.4 4,-3.0 1,-0.2 5,-0.4 0.365 48.6 109.0 -87.6 2.5 8.5 51.7 5.7 60 85 A K H > S+ 0 0 146 1,-0.2 4,-1.7 2,-0.2 -1,-0.2 0.911 87.7 31.1 -52.1 -54.4 10.4 53.1 8.8 61 86 A D H > S+ 0 0 66 -3,-0.3 4,-2.5 2,-0.2 -1,-0.2 0.903 118.9 52.3 -75.2 -39.6 10.4 50.0 11.0 62 87 A A H > S+ 0 0 0 -4,-0.3 4,-2.1 -18,-0.3 -2,-0.2 0.930 112.1 47.0 -64.1 -41.8 10.5 47.4 8.2 63 88 A D H X S+ 0 0 57 -4,-3.0 4,-2.7 1,-0.2 -1,-0.2 0.886 110.0 53.6 -64.7 -39.5 13.5 49.1 6.6 64 89 A A H X S+ 0 0 28 -4,-1.7 4,-2.4 -5,-0.4 -2,-0.2 0.918 108.0 51.3 -60.7 -40.4 15.2 49.4 10.0 65 90 A F H X S+ 0 0 1 -4,-2.5 4,-2.4 2,-0.2 -2,-0.2 0.944 111.9 45.3 -59.7 -46.5 14.7 45.6 10.5 66 91 A V H X S+ 0 0 5 -4,-2.1 4,-2.3 1,-0.2 -1,-0.2 0.886 112.5 51.7 -71.0 -35.4 16.3 44.8 7.1 67 92 A A H X S+ 0 0 61 -4,-2.7 4,-2.9 2,-0.2 -1,-0.2 0.891 108.7 51.6 -64.2 -38.4 19.1 47.3 7.8 68 93 A F H X S+ 0 0 8 -4,-2.4 4,-2.1 2,-0.2 -2,-0.2 0.940 111.7 45.9 -64.6 -47.2 19.8 45.6 11.1 69 94 A G H <>S+ 0 0 0 -4,-2.4 5,-2.7 1,-0.2 4,-0.4 0.891 114.9 47.9 -65.0 -36.6 20.0 42.1 9.5 70 95 A T H ><5S+ 0 0 89 -4,-2.3 3,-1.0 3,-0.2 -2,-0.2 0.932 109.2 53.1 -66.8 -42.7 22.2 43.4 6.7 71 96 A K H 3<5S+ 0 0 148 -4,-2.9 -2,-0.2 1,-0.3 -1,-0.2 0.901 119.5 34.4 -59.6 -41.0 24.5 45.2 9.2 72 97 A H T 3<5S- 0 0 50 -4,-2.1 -1,-0.3 -5,-0.2 -2,-0.2 0.332 107.4-121.3 -98.1 8.4 25.0 42.0 11.2 73 98 A N T < 5 + 0 0 151 -3,-1.0 2,-0.4 -4,-0.4 -3,-0.2 0.931 55.2 161.9 45.9 54.9 24.8 39.6 8.2 74 99 A L < - 0 0 13 -5,-2.7 -36,-0.2 -6,-0.1 2,-0.2 -0.788 47.1-109.7-101.5 142.1 21.9 37.7 9.7 75 100 A H E -c 38 0A 49 -38,-2.4 -36,-2.4 -2,-0.4 2,-0.4 -0.540 41.7-149.2 -61.1 134.2 19.5 35.4 7.9 76 101 A M E -c 39 0A 8 47,-0.3 50,-1.6 -2,-0.2 49,-1.2 -0.950 13.7-160.8-124.0 132.6 16.2 37.2 7.7 77 102 A V E -d 126 0A 0 -38,-2.4 2,-0.2 -2,-0.4 50,-0.2 -0.938 17.4-137.0-109.4 119.3 12.7 35.8 7.6 78 103 A G E -d 127 0A 0 48,-3.1 50,-2.8 -2,-0.5 2,-0.3 -0.567 22.8-137.6 -70.3 136.8 9.8 38.0 6.4 79 104 A H E -d 128 0A 6 -2,-0.2 -34,-0.5 1,-0.2 50,-0.1 -0.925 57.7 -18.9-143.8 115.3 6.7 37.7 8.6 80 105 A T E + 0 0 3 48,-0.6 -33,-0.5 -2,-0.3 -1,-0.2 0.669 38.4 173.1-148.0 145.4 4.0 37.5 7.1 81 106 A L E S+ 0 0 1 47,-2.2 2,-0.5 1,-0.2 49,-0.2 0.952 86.4 23.3 -72.6 -48.2 2.5 38.2 3.8 82 107 A V E S+d 130 0A 0 47,-2.1 49,-1.9 46,-0.3 2,-0.3 -0.959 75.7 134.8-130.0 112.0 -1.1 36.7 4.1 83 108 A W - 0 0 27 -2,-0.5 49,-0.1 47,-0.2 -36,-0.1 -0.982 52.4-129.8-154.2 152.2 -2.7 36.2 7.5 84 109 A H S S+ 0 0 63 47,-0.4 3,-0.3 -2,-0.3 2,-0.3 0.549 85.5 75.0 -85.6 -8.1 -6.1 36.9 9.1 85 110 A S S S+ 0 0 48 1,-0.2 -37,-0.3 3,-0.0 -38,-0.2 -0.723 93.2 18.3-106.9 155.3 -4.8 38.8 12.1 86 111 A Q S S+ 0 0 76 -2,-0.3 -38,-2.6 1,-0.2 -37,-0.4 0.929 95.9 116.9 51.8 49.8 -3.3 42.3 12.5 87 112 A I S S- 0 0 22 -3,-0.3 -1,-0.2 -40,-0.2 -34,-0.0 -0.984 71.0-103.5-146.9 137.5 -4.9 43.3 9.2 88 113 A H > - 0 0 47 -2,-0.3 3,-1.9 1,-0.1 4,-0.4 -0.316 15.7-135.2 -64.9 137.9 -7.5 46.0 8.6 89 114 A D G >> S+ 0 0 92 1,-0.3 4,-2.0 2,-0.2 3,-1.4 0.786 102.6 75.6 -57.7 -26.8 -11.1 44.9 8.0 90 115 A E G 34 S+ 0 0 103 1,-0.3 -1,-0.3 2,-0.2 -2,-0.1 0.675 82.6 66.7 -59.5 -20.7 -11.1 47.5 5.2 91 116 A V G <4 S+ 0 0 10 -3,-1.9 -1,-0.3 1,-0.2 -2,-0.2 0.887 117.9 21.1 -65.0 -35.8 -9.0 45.1 3.2 92 117 A F T <4 S+ 0 0 2 -3,-1.4 8,-2.3 -4,-0.4 2,-0.3 0.620 118.8 56.5-106.5 -19.6 -12.0 42.7 2.9 93 118 A K B < -J 99 0C 62 -4,-2.0 6,-0.2 6,-0.3 2,-0.1 -0.898 66.5-126.4-129.2 144.3 -15.1 44.8 3.5 94 119 A N > - 0 0 81 4,-3.0 3,-2.2 -2,-0.3 -2,-0.1 -0.420 49.1 -99.9 -68.3 162.7 -17.0 47.8 2.4 95 120 A A T 3 S+ 0 0 118 1,-0.3 -1,-0.1 -2,-0.1 -5,-0.0 0.753 124.2 62.7 -61.0 -23.4 -17.7 50.2 5.2 96 121 A D T 3 S- 0 0 131 2,-0.1 -1,-0.3 1,-0.0 3,-0.1 0.446 121.8-105.3 -80.5 -2.3 -21.3 48.7 5.4 97 122 A G S < S+ 0 0 41 -3,-2.2 -2,-0.1 1,-0.3 -1,-0.0 0.152 78.5 131.6 99.8 -17.4 -19.8 45.4 6.4 98 123 A S - 0 0 51 -5,-0.1 -4,-3.0 1,-0.1 -1,-0.3 -0.309 59.6-110.2 -70.3 151.8 -20.3 43.6 3.0 99 124 A Y B -J 93 0C 86 -6,-0.2 -6,-0.3 -3,-0.1 -1,-0.1 -0.573 24.5-124.9 -80.9 144.4 -17.4 41.7 1.5 100 125 A I - 0 0 23 -8,-2.3 -1,-0.1 -2,-0.2 -9,-0.0 -0.326 42.8 -82.4 -74.4 168.8 -15.7 42.8 -1.7 101 126 A S > - 0 0 68 1,-0.1 4,-2.3 -2,-0.1 5,-0.2 -0.248 32.3-113.7 -70.4 160.7 -15.4 40.5 -4.7 102 127 A K H > S+ 0 0 91 1,-0.2 4,-3.0 2,-0.2 5,-0.2 0.913 119.1 53.3 -58.6 -41.7 -12.8 37.8 -5.0 103 128 A A H > S+ 0 0 76 1,-0.2 4,-2.0 2,-0.2 -1,-0.2 0.895 108.3 48.9 -62.4 -40.5 -11.3 39.7 -8.0 104 129 A A H > S+ 0 0 38 2,-0.2 4,-1.5 1,-0.2 -1,-0.2 0.910 113.8 46.1 -67.0 -39.5 -11.0 42.9 -5.9 105 130 A L H X S+ 0 0 0 -4,-2.3 4,-2.7 1,-0.2 -2,-0.2 0.908 108.7 55.9 -70.4 -38.2 -9.3 41.1 -3.1 106 131 A Q H X S+ 0 0 34 -4,-3.0 4,-2.8 1,-0.2 -1,-0.2 0.918 105.7 52.3 -57.5 -42.1 -7.0 39.3 -5.5 107 132 A K H X S+ 0 0 151 -4,-2.0 4,-2.4 1,-0.2 -1,-0.2 0.891 109.7 48.8 -63.0 -38.9 -5.9 42.7 -6.8 108 133 A K H X S+ 0 0 59 -4,-1.5 4,-2.6 2,-0.2 -1,-0.2 0.909 111.0 49.9 -68.6 -40.8 -5.1 43.8 -3.3 109 134 A M H X S+ 0 0 0 -4,-2.7 4,-2.8 2,-0.2 5,-0.3 0.936 110.6 50.9 -61.1 -44.3 -3.1 40.6 -2.6 110 135 A E H X S+ 0 0 76 -4,-2.8 4,-2.5 1,-0.2 5,-0.3 0.934 112.2 45.8 -58.0 -47.7 -1.2 41.1 -5.8 111 136 A E H X S+ 0 0 99 -4,-2.4 4,-2.2 1,-0.2 5,-0.3 0.918 114.0 49.1 -63.3 -42.8 -0.3 44.7 -5.0 112 137 A H H X S+ 0 0 0 -4,-2.6 4,-2.9 2,-0.2 5,-0.3 0.959 116.2 39.8 -65.2 -49.1 0.7 43.8 -1.4 113 138 A I H X>S+ 0 0 0 -4,-2.8 4,-1.9 2,-0.2 5,-0.9 0.928 115.3 51.3 -67.4 -44.5 2.9 40.9 -2.2 114 139 A T H X5S+ 0 0 72 -4,-2.5 4,-0.6 -5,-0.3 -1,-0.2 0.914 117.7 40.4 -60.2 -40.5 4.5 42.5 -5.3 115 140 A T H X5S+ 0 0 52 -4,-2.2 4,-2.2 -5,-0.3 -2,-0.2 0.958 122.6 36.8 -70.7 -53.3 5.3 45.6 -3.2 116 141 A L H X5S+ 0 0 0 -4,-2.9 4,-1.3 -5,-0.3 -3,-0.2 0.967 124.3 37.6 -71.6 -52.9 6.4 44.0 0.0 117 142 A A H <5S+ 0 0 0 -4,-1.9 4,-0.3 -5,-0.3 -1,-0.2 0.853 117.2 56.0 -68.3 -29.3 8.3 40.9 -1.2 118 143 A G H ><X S+ 0 0 2 -4,-1.3 3,-2.7 -5,-0.1 4,-2.0 0.210 81.5 148.7-107.7 14.7 13.2 43.1 -0.0 121 146 A K T <4 S+ 0 0 125 -3,-1.2 4,-0.1 -4,-0.3 44,-0.1 -0.230 79.2 7.7 -48.3 127.9 13.8 40.6 -2.9 122 147 A G T 34 S+ 0 0 58 2,-0.4 -1,-0.3 1,-0.1 3,-0.1 0.273 120.1 76.0 79.9 -14.6 17.2 39.0 -2.2 123 148 A K T <4 S+ 0 0 115 -3,-2.7 2,-0.5 1,-0.2 -47,-0.3 0.844 88.3 55.5 -94.4 -47.7 17.5 40.6 1.2 124 149 A L S < S- 0 0 2 -4,-2.0 -2,-0.4 -7,-0.2 -1,-0.2 -0.802 70.0-159.3 -84.4 126.3 15.1 38.4 3.1 125 150 A A S S+ 0 0 41 -49,-1.2 44,-2.5 -2,-0.5 2,-0.3 0.750 71.9 16.8 -74.2 -27.6 16.1 34.7 2.7 126 151 A A E -de 77 169A 1 -50,-1.6 -48,-3.1 42,-0.3 2,-0.4 -0.966 62.7-151.0-146.0 157.3 12.7 33.4 3.5 127 152 A W E -de 78 170A 2 42,-2.2 44,-2.9 -2,-0.3 2,-1.2 -0.999 20.6-138.6-132.1 135.4 9.0 34.4 3.9 128 153 A D E +de 79 171A 3 -50,-2.8 -47,-2.2 -2,-0.4 -48,-0.6 -0.809 34.1 179.3 -75.5 99.6 6.1 33.2 6.0 129 154 A V E + 0 0 0 42,-2.1 -47,-2.1 -2,-1.2 2,-0.4 0.947 65.5 15.9 -75.6 -49.7 3.8 33.4 2.9 130 155 A V E S-de 82 172A 0 41,-1.0 43,-2.1 -49,-0.2 2,-0.4 -0.985 72.5-163.1-126.9 137.9 0.7 32.2 4.7 131 156 A N E - e 0 173A 4 -49,-1.9 -47,-0.4 -2,-0.4 43,-0.2 -0.964 63.2 -8.6-118.5 132.8 0.2 32.0 8.5 132 157 A E + 0 0 23 41,-2.7 -48,-0.2 -2,-0.4 -1,-0.1 0.845 67.1 153.1 62.3 50.9 -2.4 30.1 10.4 133 158 A A + 0 0 3 40,-0.3 8,-2.9 -3,-0.1 2,-0.5 0.528 51.4 77.7 -92.7 -8.2 -4.8 28.9 7.7 134 159 A V B S-K 140 0D 2 6,-0.3 6,-0.2 8,-0.1 52,-0.0 -0.899 78.7-133.4-104.6 128.1 -6.2 25.7 9.5 135 160 A G > - 0 0 5 4,-3.0 3,-1.9 -2,-0.5 6,-0.1 -0.291 22.4-109.8 -77.5 167.0 -8.8 26.4 12.2 136 161 A D T 3 S+ 0 0 87 1,-0.3 -1,-0.1 2,-0.1 46,-0.1 0.738 119.2 62.7 -73.1 -14.4 -8.7 24.8 15.6 137 162 A D T 3 S- 0 0 111 2,-0.2 -1,-0.3 3,-0.1 3,-0.1 0.275 118.9-112.2 -83.3 7.0 -11.7 22.7 14.6 138 163 A L S < S+ 0 0 83 -3,-1.9 2,-0.2 1,-0.3 -2,-0.1 0.443 86.8 107.2 72.3 4.3 -9.5 21.1 11.9 139 164 A K S S- 0 0 95 1,-0.2 -4,-3.0 -5,-0.0 -1,-0.3 -0.576 90.8 -71.1 -95.0 170.3 -11.4 22.7 9.0 140 165 A M B -K 134 0D 42 -6,-0.2 -6,-0.3 -2,-0.2 -1,-0.2 -0.358 65.8 -94.1 -58.0 139.7 -10.0 25.6 7.0 141 166 A R - 0 0 38 -8,-2.9 2,-1.9 1,-0.1 5,-0.2 -0.423 30.9-128.8 -62.2 133.8 -9.9 28.7 9.2 142 167 A D + 0 0 119 -2,-0.1 -1,-0.1 4,-0.1 2,-0.1 -0.316 56.0 146.9 -82.7 52.7 -13.1 30.7 8.5 143 168 A S > - 0 0 12 -2,-1.9 4,-2.7 -10,-0.1 5,-0.2 -0.354 66.1-106.0 -82.8 168.3 -11.2 34.0 7.9 144 169 A H H > S+ 0 0 47 1,-0.2 4,-2.4 2,-0.2 5,-0.3 0.906 121.3 58.8 -59.3 -39.6 -12.2 36.7 5.5 145 170 A W H > S+ 0 0 2 1,-0.2 4,-2.3 2,-0.2 5,-0.3 0.933 112.4 38.0 -48.5 -49.6 -9.4 35.5 3.2 146 171 A Y H > S+ 0 0 81 2,-0.2 4,-2.2 3,-0.2 -2,-0.2 0.893 113.4 54.0 -77.4 -39.5 -10.9 32.0 3.0 147 172 A K H < S+ 0 0 125 -4,-2.7 -1,-0.2 1,-0.2 -2,-0.2 0.901 118.7 36.1 -63.1 -37.9 -14.6 33.1 2.9 148 173 A I H < S+ 0 0 24 -4,-2.4 -2,-0.2 -5,-0.2 -1,-0.2 0.904 134.2 19.5 -80.1 -42.2 -13.9 35.4 -0.1 149 174 A M H >< S- 0 0 6 -4,-2.3 3,-0.8 -5,-0.3 -3,-0.2 0.646 85.1-145.5-108.5 -18.5 -11.3 33.4 -2.0 150 175 A G T >< - 0 0 24 -4,-2.2 3,-2.1 -5,-0.3 4,-0.3 -0.330 68.6 -33.0 72.1-165.4 -11.4 29.8 -1.0 151 176 A D T >> S+ 0 0 75 1,-0.3 4,-2.1 2,-0.2 3,-1.1 0.647 125.2 85.2 -67.3 -8.1 -8.1 27.9 -0.9 152 177 A D H <> S+ 0 0 37 -3,-0.8 4,-3.0 1,-0.2 5,-0.4 0.779 75.9 70.4 -58.7 -25.3 -7.0 30.0 -3.8 153 178 A F H <> S+ 0 0 5 -3,-2.1 4,-1.4 2,-0.2 -1,-0.2 0.911 106.8 37.1 -60.6 -36.4 -5.9 32.6 -1.2 154 179 A I H <> S+ 0 0 0 -3,-1.1 4,-2.2 -4,-0.3 5,-0.2 0.954 117.8 48.5 -77.5 -53.1 -3.1 30.2 -0.2 155 180 A Y H X S+ 0 0 49 -4,-2.1 4,-2.1 1,-0.2 -2,-0.2 0.894 115.6 44.6 -52.3 -47.7 -2.3 29.0 -3.7 156 181 A N H X S+ 0 0 33 -4,-3.0 4,-3.0 2,-0.2 5,-0.2 0.882 109.0 56.4 -70.1 -36.6 -2.1 32.5 -5.2 157 182 A A H X S+ 0 0 0 -4,-1.4 4,-2.5 -5,-0.4 -2,-0.2 0.930 112.1 42.0 -58.9 -47.8 -0.1 33.9 -2.2 158 183 A F H X S+ 0 0 0 -4,-2.2 4,-2.4 2,-0.2 -1,-0.2 0.923 114.5 50.6 -66.0 -42.8 2.7 31.3 -2.7 159 184 A T H X S+ 0 0 36 -4,-2.1 4,-1.8 -5,-0.2 -2,-0.2 0.933 113.3 46.4 -61.8 -45.9 2.6 31.6 -6.5 160 185 A L H X S+ 0 0 18 -4,-3.0 4,-2.1 2,-0.2 -1,-0.2 0.916 112.0 49.2 -60.9 -49.3 2.9 35.5 -6.3 161 186 A A H X S+ 0 0 2 -4,-2.5 4,-2.8 -5,-0.2 -1,-0.2 0.913 111.0 51.5 -58.9 -40.0 5.7 35.4 -3.7 162 187 A N H < S+ 0 0 50 -4,-2.4 -1,-0.2 1,-0.2 -2,-0.2 0.840 110.3 48.5 -68.3 -33.0 7.6 32.9 -5.9 163 188 A E H < S+ 0 0 129 -4,-1.8 -1,-0.2 -5,-0.2 -2,-0.2 0.833 114.0 46.8 -70.4 -35.4 7.2 35.2 -9.0 164 189 A V H < S+ 0 0 29 -4,-2.1 -2,-0.2 1,-0.3 -3,-0.2 0.917 132.5 13.0 -78.1 -44.6 8.4 38.2 -7.0 165 190 A D >< - 0 0 6 -4,-2.8 3,-1.6 -5,-0.2 -1,-0.3 -0.743 65.1-179.2-131.8 89.3 11.4 36.6 -5.4 166 191 A P T 3 S+ 0 0 89 0, 0.0 -1,-0.1 0, 0.0 -4,-0.1 0.660 83.4 55.5 -60.4 -16.8 12.2 33.2 -7.0 167 192 A K T 3 S+ 0 0 189 2,-0.1 2,-0.1 -41,-0.0 -5,-0.1 0.579 82.5 108.3 -93.2 -10.9 15.1 32.8 -4.6 168 193 A A S < S- 0 0 2 -3,-1.6 2,-0.7 -7,-0.2 -42,-0.3 -0.394 72.9-125.3 -70.0 141.4 13.1 33.1 -1.4 169 194 A H E -e 126 0A 41 -44,-2.5 -42,-2.2 -2,-0.1 2,-0.4 -0.818 32.5-147.9 -86.1 114.3 12.5 30.1 0.8 170 195 A L E -e 127 0A 0 -2,-0.7 31,-2.6 -44,-0.2 32,-2.4 -0.749 17.8-171.7 -96.7 130.0 8.7 30.1 1.1 171 196 A M E -ef 128 202A 0 -44,-2.9 -42,-2.1 -2,-0.4 -41,-1.0 -0.905 26.1-146.8-125.6 146.9 7.0 28.7 4.2 172 197 A Y E -ef 130 203A 0 30,-1.6 32,-3.5 -2,-0.4 2,-0.4 -0.916 31.0-164.8 -98.1 136.5 3.6 27.9 5.5 173 198 A N E +ef 131 204A 0 -43,-2.1 -41,-2.7 -2,-0.4 2,-0.3 -0.968 16.3 152.3-131.1 137.6 3.5 28.6 9.3 174 199 A D E - f 0 205A 0 30,-1.9 32,-2.8 -2,-0.4 2,-0.3 -0.991 32.9-120.3-158.5 162.9 1.1 27.5 12.0 175 200 A Y S S+ 0 0 48 -2,-0.3 30,-0.0 30,-0.2 29,-0.0 -0.732 89.0 22.7-104.0 156.3 0.6 26.8 15.7 176 201 A N S > S+ 0 0 52 -2,-0.3 3,-1.4 32,-0.1 7,-0.3 0.545 78.3 121.4 66.2 11.7 -0.6 23.5 17.4 177 202 A I T 3 + 0 0 0 1,-0.3 -1,-0.1 -3,-0.2 4,-0.1 0.424 59.7 77.2 -82.2 3.4 0.5 21.6 14.3 178 203 A E T 3 S+ 0 0 2 2,-0.1 44,-0.3 44,-0.1 2,-0.3 0.534 89.1 80.9 -72.1 -15.8 2.7 19.7 16.9 179 204 A R S <> S- 0 0 84 -3,-1.4 4,-2.5 42,-0.1 5,-0.2 -0.699 90.9-102.7-107.9 148.4 -0.5 18.0 17.8 180 205 A T T 4 S+ 0 0 85 -2,-0.3 2,-0.7 1,-0.2 -1,-0.1 -0.402 106.1 30.0 -62.0 138.2 -2.5 15.1 16.5 181 206 A G T > S+ 0 0 22 -4,-0.1 4,-2.2 1,-0.1 5,-0.2 -0.776 121.7 47.4 110.1 -77.2 -5.6 16.4 14.6 182 207 A K H > S+ 0 0 6 -2,-0.7 4,-2.2 -6,-0.3 5,-0.2 0.844 107.1 59.2 -67.0 -34.4 -4.2 19.7 13.3 183 208 A R H X S+ 0 0 3 -4,-2.5 4,-2.6 -7,-0.3 -1,-0.2 0.964 109.7 42.0 -53.5 -53.5 -1.0 18.0 12.1 184 209 A E H > S+ 0 0 85 1,-0.2 4,-2.3 -5,-0.2 -2,-0.2 0.869 112.2 53.6 -69.9 -36.2 -2.9 15.7 9.8 185 210 A A H X S+ 0 0 25 -4,-2.2 4,-2.1 2,-0.2 -1,-0.2 0.880 111.6 47.3 -61.4 -38.8 -5.3 18.4 8.6 186 211 A T H X S+ 0 0 0 -4,-2.2 4,-2.7 2,-0.2 5,-0.3 0.921 109.7 51.6 -72.4 -41.8 -2.2 20.5 7.7 187 212 A V H X S+ 0 0 25 -4,-2.6 4,-2.8 1,-0.2 -2,-0.2 0.923 110.9 49.4 -56.3 -44.7 -0.5 17.6 5.9 188 213 A E H X S+ 0 0 66 -4,-2.3 4,-1.8 1,-0.2 -2,-0.2 0.937 112.3 47.3 -64.6 -44.8 -3.6 17.0 3.8 189 214 A M H X S+ 0 0 23 -4,-2.1 4,-1.5 1,-0.2 -1,-0.2 0.930 116.2 42.8 -60.6 -50.3 -4.0 20.7 2.9 190 215 A I H X S+ 0 0 0 -4,-2.7 4,-3.0 1,-0.2 5,-0.2 0.914 109.7 57.7 -65.2 -43.3 -0.3 21.1 1.9 191 216 A E H X S+ 0 0 87 -4,-2.8 4,-2.1 -5,-0.3 -1,-0.2 0.899 110.4 42.9 -52.8 -45.5 -0.1 17.8 0.1 192 217 A R H X S+ 0 0 179 -4,-1.8 4,-1.5 2,-0.2 -1,-0.2 0.751 111.9 52.6 -81.4 -24.9 -2.9 18.7 -2.2 193 218 A L H <>S+ 0 0 4 -4,-1.5 5,-2.4 -5,-0.2 4,-0.4 0.911 110.0 50.5 -71.2 -40.1 -1.7 22.2 -2.8 194 219 A Q H ><5S+ 0 0 55 -4,-3.0 3,-1.5 3,-0.2 -2,-0.2 0.913 108.9 50.4 -60.7 -43.0 1.7 20.8 -3.7 195 220 A K H 3<5S+ 0 0 93 -4,-2.1 -1,-0.2 1,-0.3 -2,-0.2 0.876 104.4 58.1 -63.9 -35.3 0.1 18.4 -6.2 196 221 A R T 3<5S- 0 0 106 -4,-1.5 -1,-0.3 -5,-0.1 -2,-0.2 0.579 128.2-104.7 -67.6 -12.6 -1.8 21.4 -7.7 197 222 A G T < 5 + 0 0 49 -3,-1.5 -3,-0.2 -4,-0.4 -2,-0.2 0.597 61.2 163.6 101.1 15.1 1.8 22.7 -8.3 198 223 A M < - 0 0 9 -5,-2.4 2,-0.3 -8,-0.1 -1,-0.2 -0.465 39.6-123.1 -69.3 132.0 2.0 25.3 -5.5 199 224 A P + 0 0 29 0, 0.0 2,-0.3 0, 0.0 -37,-0.1 -0.614 48.3 149.4 -75.0 131.0 5.6 26.4 -4.8 200 225 A I + 0 0 16 -2,-0.3 -29,-0.2 1,-0.1 3,-0.1 -0.877 22.0 176.1-163.5 134.3 6.5 25.9 -1.2 201 226 A H + 0 0 68 -31,-2.6 31,-2.3 -2,-0.3 2,-0.3 0.657 62.9 31.0-113.8 -28.6 9.9 25.1 0.3 202 227 A G E -fg 171 232A 0 -32,-2.4 -30,-1.6 29,-0.3 2,-0.5 -0.931 54.3-144.2-141.2 159.7 9.4 25.0 4.1 203 228 A L E -fg 172 233A 0 29,-2.9 31,-2.6 -2,-0.3 2,-0.6 -0.991 18.6-151.2-129.7 120.1 7.0 24.3 6.9 204 229 A G E -fg 173 234A 0 -32,-3.5 -30,-1.9 -2,-0.5 2,-0.6 -0.838 6.3-166.2 -96.9 118.9 7.0 26.4 10.0 205 230 A I E -fg 174 235A 0 29,-3.2 31,-2.1 -2,-0.6 32,-0.5 -0.932 14.8-149.7 -97.5 120.1 5.9 24.9 13.3 206 231 A Q - 0 0 8 -32,-2.8 31,-2.4 -2,-0.6 -31,-0.2 0.932 13.1-153.3 -62.5 -44.7 5.4 27.8 15.7 207 232 A G + 0 0 0 -33,-0.3 32,-1.7 1,-0.2 2,-1.4 0.860 27.8 165.3 74.4 35.7 6.3 26.0 18.9 208 233 A H E -l 239 0E 43 30,-0.2 -1,-0.2 32,-0.1 2,-0.2 -0.744 29.2-177.0 -77.1 93.3 4.4 28.0 21.4 209 234 A L E -l 240 0E 5 30,-2.5 32,-2.7 -2,-1.4 2,-0.2 -0.548 27.5-129.9 -99.7 156.3 4.8 25.3 24.0 210 235 A G E -l 241 0E 20 3,-2.9 32,-0.2 30,-0.2 -1,-0.0 -0.635 35.7-106.3 -90.2 162.4 3.6 24.8 27.5 211 236 A I S S+ 0 0 25 30,-1.7 31,-0.1 -2,-0.2 -1,-0.1 0.820 118.8 13.2 -56.4 -30.5 5.9 23.9 30.3 212 237 A D S S+ 0 0 108 1,-0.2 -1,-0.1 3,-0.0 30,-0.0 0.800 109.0 96.5-108.6 -48.6 4.4 20.3 30.2 213 238 A T + 0 0 80 2,-0.1 -3,-2.9 3,-0.0 -1,-0.2 -0.701 65.0 35.2-108.6 149.1 2.3 20.0 26.9 214 239 A P S S- 0 0 3 0, 0.0 -4,-0.1 0, 0.0 2,-0.1 0.649 85.8-127.8 -80.7 162.6 2.6 19.0 24.2 215 240 A P >> - 0 0 69 0, 0.0 4,-1.6 0, 0.0 3,-1.2 -0.367 19.7-111.4 -72.3 153.2 4.8 15.9 24.8 216 241 A I H 3> S+ 0 0 43 1,-0.2 4,-2.8 2,-0.2 5,-0.2 0.845 114.9 62.3 -47.5 -42.0 8.0 15.4 22.8 217 242 A A H 3> S+ 0 0 53 1,-0.2 4,-1.7 2,-0.2 -1,-0.2 0.832 103.7 48.2 -59.6 -34.1 6.5 12.3 21.1 218 243 A E H <> S+ 0 0 39 -3,-1.2 4,-1.6 2,-0.2 -1,-0.2 0.926 111.6 48.1 -70.0 -46.1 3.8 14.5 19.5 219 244 A I H X S+ 0 0 1 -4,-1.6 4,-2.3 1,-0.2 -2,-0.2 0.914 109.7 55.2 -61.3 -40.8 6.3 17.1 18.3 220 245 A E H X S+ 0 0 41 -4,-2.8 4,-2.4 1,-0.2 5,-0.2 0.915 103.4 53.9 -58.6 -43.7 8.4 14.3 16.9 221 246 A K H X S+ 0 0 112 -4,-1.7 4,-2.6 1,-0.2 -1,-0.2 0.886 110.1 48.7 -60.2 -36.3 5.5 12.9 14.8 222 247 A S H X S+ 0 0 0 -4,-1.6 4,-2.7 -44,-0.3 5,-0.3 0.898 107.8 51.9 -71.7 -42.8 5.1 16.4 13.3 223 248 A I H X S+ 0 0 0 -4,-2.3 4,-2.1 1,-0.2 -2,-0.2 0.967 115.6 43.6 -56.0 -48.2 8.7 16.8 12.4 224 249 A I H X S+ 0 0 53 -4,-2.4 4,-1.8 1,-0.2 -2,-0.2 0.931 114.6 48.2 -64.6 -46.0 8.7 13.5 10.7 225 250 A A H < S+ 0 0 24 -4,-2.6 4,-0.4 -5,-0.2 -1,-0.2 0.908 113.7 45.3 -61.9 -44.9 5.3 14.0 8.9 226 251 A F H ><>S+ 0 0 0 -4,-2.7 3,-1.1 1,-0.2 5,-0.9 0.873 109.8 54.8 -73.8 -34.3 6.2 17.5 7.5 227 252 A A H ><5S+ 0 0 25 -4,-2.1 3,-2.2 -5,-0.3 4,-0.3 0.885 98.5 64.4 -61.3 -33.9 9.6 16.4 6.4 228 253 A K T 3<5S+ 0 0 170 -4,-1.8 -1,-0.2 1,-0.3 -2,-0.2 0.702 90.0 66.9 -64.8 -17.7 7.9 13.6 4.4 229 254 A L T < 5S- 0 0 20 -3,-1.1 -1,-0.3 -4,-0.4 -2,-0.2 0.385 121.1-107.9 -78.7 0.5 6.3 16.3 2.3 230 255 A G T < 5S+ 0 0 70 -3,-2.2 2,-0.3 1,-0.3 -2,-0.2 0.764 79.7 131.5 75.0 28.3 9.7 17.2 1.0 231 256 A L < - 0 0 6 -5,-0.9 2,-0.3 -4,-0.3 -1,-0.3 -0.859 62.5-117.0-112.5 145.0 9.7 20.4 3.0 232 257 A R E -g 202 0A 89 -31,-2.3 -29,-2.9 -2,-0.3 2,-0.4 -0.636 33.7-132.6 -74.2 136.6 12.4 21.8 5.3 233 258 A V E -gh 203 297A 0 63,-2.4 65,-2.7 -2,-0.3 66,-0.8 -0.808 25.2-176.7 -97.4 131.1 11.1 22.0 8.9 234 259 A H E -gh 204 299A 3 -31,-2.6 -29,-3.2 -2,-0.4 2,-0.6 -0.989 23.7-145.2-123.7 139.4 11.5 25.2 10.9 235 260 A F E +gh 205 300A 1 64,-2.7 66,-3.1 -2,-0.4 -29,-0.2 -0.939 31.1 174.8 -97.2 120.0 10.6 26.0 14.5 236 261 A T E + 0 0 2 -31,-2.1 -30,-0.2 -2,-0.6 -29,-0.1 0.664 59.0 24.1-109.2 -23.6 9.6 29.6 14.1 237 262 A S E S- 0 0 3 -31,-2.4 65,-0.2 -32,-0.5 -1,-0.1 -0.252 74.9-179.4-145.9 45.4 8.2 31.1 17.3 238 263 A L E + h 0 302A 0 63,-2.9 65,-2.6 -3,-0.1 2,-0.3 -0.251 16.4 135.5 -64.8 134.6 9.5 29.1 20.2 239 264 A D E -l 208 0E 1 -32,-1.7 -30,-2.5 63,-0.2 2,-0.5 -0.947 42.1-133.4-164.2 163.3 8.6 29.9 23.8 240 265 A V E -l 209 0E 1 84,-1.5 2,-0.6 -2,-0.3 -30,-0.2 -0.966 16.0-144.2-127.9 113.2 7.6 28.0 26.9 241 266 A D E +l 210 0E 20 -32,-2.7 -30,-1.7 -2,-0.5 4,-0.1 -0.686 19.6 177.6 -80.2 118.8 4.6 29.3 28.9 242 267 A V + 0 0 6 -2,-0.6 -1,-0.1 -32,-0.2 3,-0.1 0.321 48.4 96.1-102.2 4.6 5.3 28.7 32.6 243 268 A L S S- 0 0 10 1,-0.1 -32,-0.2 22,-0.0 22,-0.1 -0.640 90.8 -74.0-101.2 156.9 2.1 30.3 34.0 244 269 A P - 0 0 52 0, 0.0 2,-0.2 0, 0.0 -1,-0.1 -0.171 57.4-123.8 -48.8 130.1 -1.2 28.7 35.0 245 270 A S - 0 0 67 1,-0.1 3,-0.1 -3,-0.1 -35,-0.0 -0.560 28.3-176.1 -86.6 141.3 -3.1 27.8 31.8 246 271 A V > + 0 0 2 -2,-0.2 3,-0.8 1,-0.1 -1,-0.1 0.275 65.6 95.3-112.0 6.2 -6.6 29.0 30.9 247 272 A W T 3 S+ 0 0 127 1,-0.2 -1,-0.1 10,-0.0 -2,-0.0 0.665 88.6 40.2 -72.3 -15.7 -6.8 26.8 27.8 248 273 A E T 3 S+ 0 0 177 -3,-0.1 -1,-0.2 2,-0.0 -2,-0.0 -0.206 83.4 141.1-129.3 42.4 -8.6 23.9 29.5 249 274 A L < - 0 0 58 -3,-0.8 5,-0.1 1,-0.1 -3,-0.1 -0.508 55.2 -90.4 -94.7 154.3 -11.1 25.5 31.8 250 275 A P > - 0 0 77 0, 0.0 3,-1.6 0, 0.0 4,-0.4 -0.120 41.1-107.1 -52.3 156.8 -14.8 24.6 32.7 251 276 A V G > S+ 0 0 131 1,-0.3 3,-1.1 2,-0.2 4,-0.3 0.813 117.6 62.4 -61.3 -33.4 -17.6 26.0 30.6 252 277 A A G 3 S+ 0 0 87 1,-0.2 4,-0.3 2,-0.1 -1,-0.3 0.763 108.9 43.8 -60.3 -25.1 -18.7 28.4 33.5 253 278 A E G <> S+ 0 0 66 -3,-1.6 4,-1.7 1,-0.2 -1,-0.2 0.420 80.4 105.4-101.7 -1.5 -15.3 30.1 33.1 254 279 A V T <4 S+ 0 0 80 -3,-1.1 -1,-0.2 -4,-0.4 -2,-0.1 0.815 88.5 37.4 -51.1 -38.7 -15.1 30.2 29.3 255 280 A S T >4 S+ 0 0 92 -4,-0.3 3,-0.7 -3,-0.2 -1,-0.2 0.905 121.2 41.9 -82.5 -43.6 -15.7 34.0 29.3 256 281 A T G >4 S+ 0 0 66 -4,-0.3 3,-2.1 1,-0.2 -2,-0.2 0.485 85.2 95.8 -86.3 -3.8 -13.8 35.1 32.3 257 282 A R G 3< S+ 0 0 51 -4,-1.7 -1,-0.2 1,-0.3 -2,-0.1 0.684 82.7 53.4 -66.5 -14.9 -10.7 32.9 31.8 258 283 A F G < S+ 0 0 73 -3,-0.7 -1,-0.3 -4,-0.1 2,-0.2 0.399 86.7 110.3 -97.0 4.1 -8.9 35.8 30.0 259 284 A E S < S- 0 0 124 -3,-2.1 2,-0.4 58,-0.1 -3,-0.0 -0.498 80.1-105.4 -74.7 142.4 -9.5 38.1 33.0 260 285 A Y + 0 0 110 -2,-0.2 -1,-0.1 3,-0.0 -2,-0.1 -0.588 46.0 170.4 -69.6 125.0 -6.5 39.0 35.2 261 286 A K > - 0 0 82 -2,-0.4 3,-1.7 1,-0.1 4,-0.3 -0.996 38.6-130.2-134.9 134.6 -6.6 37.2 38.5 262 287 A P G > S+ 0 0 87 0, 0.0 3,-1.9 0, 0.0 -1,-0.1 0.856 107.7 59.2 -52.0 -39.8 -3.7 37.2 41.0 263 288 A E G 3 S+ 0 0 113 1,-0.3 -3,-0.0 3,-0.1 0, 0.0 0.722 102.7 54.3 -63.5 -21.4 -3.7 33.3 41.3 264 289 A R G < S+ 0 0 18 -3,-1.7 -1,-0.3 1,-0.2 53,-0.1 0.464 109.0 49.6 -89.7 -0.9 -3.1 33.1 37.6 265 290 A D X + 0 0 8 -3,-1.9 3,-0.7 -4,-0.3 -1,-0.2 -0.593 67.5 153.1-135.8 65.4 0.0 35.3 37.9 266 291 A P T 3 + 0 0 63 0, 0.0 3,-0.2 0, 0.0 -1,-0.1 0.533 59.7 59.1 -84.1 -5.4 1.9 33.7 40.7 267 292 A Y T > + 0 0 48 54,-0.3 3,-1.7 1,-0.2 -24,-0.0 -0.032 55.0 125.7-117.6 32.7 5.5 34.7 39.9 268 293 A T T < S+ 0 0 80 -3,-0.7 -1,-0.2 1,-0.3 3,-0.1 0.820 79.3 50.5 -61.9 -26.7 5.5 38.5 39.9 269 294 A K T 3 S- 0 0 209 1,-0.3 -1,-0.3 -3,-0.2 2,-0.2 0.545 130.7 -58.4 -87.8 -3.4 8.4 38.5 42.5 270 295 A G < - 0 0 35 -3,-1.7 -1,-0.3 51,-0.1 51,-0.0 -0.629 53.5 -85.5 140.3 155.4 10.6 36.1 40.5 271 296 A L - 0 0 15 -2,-0.2 5,-0.1 -3,-0.1 -4,-0.0 -0.855 52.7-124.6 -92.3 119.3 10.5 32.6 39.0 272 297 A P >> - 0 0 50 0, 0.0 4,-2.0 0, 0.0 3,-1.1 -0.278 20.1-108.7 -67.2 155.5 11.7 30.3 41.8 273 298 A Q H 3> S+ 0 0 108 1,-0.3 4,-2.6 2,-0.2 5,-0.2 0.820 116.8 60.4 -52.3 -37.2 14.6 28.0 41.2 274 299 A E H 3> S+ 0 0 106 1,-0.2 4,-1.7 2,-0.2 -1,-0.3 0.888 108.8 43.7 -63.9 -34.9 12.4 24.8 41.1 275 300 A M H <> S+ 0 0 11 -3,-1.1 4,-2.8 2,-0.2 -1,-0.2 0.832 108.9 56.9 -76.9 -33.0 10.6 26.3 38.1 276 301 A Q H X S+ 0 0 29 -4,-2.0 4,-2.6 1,-0.2 -2,-0.2 0.923 108.0 50.1 -55.9 -43.1 13.9 27.4 36.5 277 302 A D H X S+ 0 0 80 -4,-2.6 4,-2.4 2,-0.2 -2,-0.2 0.914 111.1 46.9 -60.6 -47.9 14.8 23.8 36.8 278 303 A K H X S+ 0 0 80 -4,-1.7 4,-2.3 2,-0.2 -1,-0.2 0.897 112.9 49.6 -63.3 -41.1 11.6 22.6 35.1 279 304 A L H X S+ 0 0 0 -4,-2.8 4,-2.5 2,-0.2 -2,-0.2 0.926 110.7 49.9 -64.5 -44.0 11.9 25.2 32.4 280 305 A A H X S+ 0 0 0 -4,-2.6 4,-2.3 2,-0.2 -2,-0.2 0.911 111.7 48.3 -59.1 -44.8 15.6 24.1 31.7 281 306 A K H X S+ 0 0 97 -4,-2.4 4,-2.8 2,-0.2 -1,-0.2 0.899 110.2 52.0 -63.8 -40.0 14.6 20.5 31.5 282 307 A R H X S+ 0 0 13 -4,-2.3 4,-2.0 1,-0.2 -2,-0.2 0.933 112.5 44.3 -64.9 -46.8 11.7 21.3 29.1 283 308 A Y H X S+ 0 0 1 -4,-2.5 4,-2.7 2,-0.2 -1,-0.2 0.876 112.6 52.9 -63.0 -38.0 14.0 23.2 26.8 284 309 A E H X S+ 0 0 36 -4,-2.3 4,-2.4 2,-0.2 -2,-0.2 0.921 108.4 49.9 -64.7 -43.3 16.7 20.5 27.0 285 310 A D H X S+ 0 0 38 -4,-2.8 4,-1.7 1,-0.2 -1,-0.2 0.930 112.4 49.3 -56.0 -45.8 14.1 17.8 26.1 286 311 A L H X S+ 0 0 1 -4,-2.0 4,-2.1 1,-0.2 -2,-0.2 0.933 112.1 45.2 -63.3 -48.6 13.0 20.0 23.1 287 312 A F H X S+ 0 0 1 -4,-2.7 4,-2.8 1,-0.2 -1,-0.2 0.820 106.8 59.5 -72.2 -27.0 16.5 20.6 21.8 288 313 A K H X S+ 0 0 110 -4,-2.4 4,-2.4 2,-0.2 -1,-0.2 0.924 108.3 46.9 -57.9 -44.4 17.5 16.9 22.2 289 314 A L H X S+ 0 0 6 -4,-1.7 4,-1.7 2,-0.2 -2,-0.2 0.915 111.6 49.8 -64.4 -42.8 14.6 16.2 19.8 290 315 A F H < S+ 0 0 0 -4,-2.1 7,-0.2 2,-0.2 -2,-0.2 0.915 110.8 49.6 -63.2 -42.7 15.8 18.9 17.4 291 316 A I H >< S+ 0 0 30 -4,-2.8 3,-1.8 1,-0.2 4,-0.2 0.935 107.6 55.2 -60.4 -44.5 19.3 17.5 17.5 292 317 A K H 3< S+ 0 0 133 -4,-2.4 3,-0.3 1,-0.3 -1,-0.2 0.871 118.9 33.4 -53.8 -39.1 17.9 14.0 16.8 293 318 A H T >X S+ 0 0 11 -4,-1.7 3,-2.2 1,-0.2 4,-0.8 -0.022 76.6 129.0-110.2 29.6 16.2 15.4 13.7 294 319 A S G X4 + 0 0 34 -3,-1.8 3,-0.6 1,-0.3 -1,-0.2 0.797 66.9 66.0 -56.2 -30.5 18.8 18.0 12.7 295 320 A D G 34 S+ 0 0 101 -3,-0.3 -1,-0.3 -4,-0.2 -2,-0.1 0.752 108.2 39.9 -63.8 -21.9 18.8 16.5 9.2 296 321 A K G <4 S+ 0 0 43 -3,-2.2 -63,-2.4 -6,-0.2 2,-0.4 0.568 103.4 79.0 -98.7 -15.6 15.1 17.7 8.8 297 322 A I E << + h 0 233A 1 -4,-0.8 -63,-0.2 -3,-0.6 3,-0.1 -0.864 44.0 179.9-111.8 129.6 15.3 21.1 10.5 298 323 A D E + 0 0 52 -65,-2.7 -287,-2.4 -2,-0.4 2,-0.3 0.686 68.4 3.6 -92.0 -25.0 16.7 24.3 9.0 299 324 A R E -ah 11 234A 1 -66,-0.8 -64,-2.7 -289,-0.3 2,-0.4 -0.992 42.5-153.4-165.5 145.6 16.1 26.7 12.0 300 325 A A E -ah 12 235A 0 -289,-2.5 -287,-2.5 -2,-0.3 2,-0.4 -0.927 25.8-176.5-127.7 106.6 15.0 27.2 15.5 301 326 A T E -a 13 0A 0 -66,-3.1 -63,-2.9 -2,-0.4 2,-0.3 -0.891 16.2-143.3-104.6 131.5 13.7 30.7 16.2 302 327 A F E -ah 14 238A 5 -289,-2.6 -287,-2.3 -2,-0.4 2,-2.2 -0.703 22.3-121.3 -89.6 142.8 12.6 32.0 19.6 303 328 A W S S- 0 0 17 -65,-2.6 8,-0.5 -2,-0.3 2,-0.2 -0.398 88.7 -7.5 -85.6 64.3 9.7 34.4 19.7 304 329 A G - 0 0 3 -2,-2.2 -289,-0.1 6,-0.1 -288,-0.1 -0.548 68.0-114.3 133.0 165.3 11.7 37.1 21.5 305 330 A V S S+ 0 0 2 1,-0.3 22,-0.7 -290,-0.2 21,-0.3 0.882 90.2 15.8 -97.0 -51.6 15.2 37.5 23.0 306 331 A S B > S-m 327 0F 1 20,-0.1 3,-1.6 19,-0.1 4,-0.4 -0.867 77.4-108.0-130.2 159.3 14.5 38.1 26.7 307 332 A D G > S+ 0 0 0 20,-2.4 3,-1.2 -2,-0.3 15,-0.2 0.765 109.8 66.3 -55.7 -30.6 11.6 37.6 29.0 308 333 A D G 3 S+ 0 0 84 1,-0.3 -1,-0.3 20,-0.2 21,-0.1 0.820 106.9 41.7 -64.2 -28.6 10.8 41.3 29.4 309 334 A A G < S+ 0 0 26 -3,-1.6 -1,-0.3 4,-0.0 -2,-0.2 0.393 84.8 127.5 -99.7 2.2 9.8 41.6 25.7 310 335 A S X - 0 0 5 -3,-1.2 3,-1.8 -4,-0.4 4,-0.3 -0.377 58.8-140.1 -69.6 136.6 7.8 38.3 25.4 311 336 A W G >> S+ 0 0 80 -8,-0.5 3,-1.2 1,-0.3 4,-0.8 0.694 97.7 75.4 -63.9 -17.1 4.3 38.5 24.0 312 337 A L G 34 S+ 0 0 7 1,-0.3 5,-0.3 2,-0.2 -1,-0.3 0.609 78.7 71.6 -76.1 -10.9 3.3 35.9 26.7 313 338 A N G <4 S+ 0 0 25 -3,-1.8 7,-2.4 1,-0.2 -1,-0.3 0.803 115.3 24.8 -65.0 -29.3 3.4 38.7 29.3 314 339 A G T <4 S+ 0 0 44 -3,-1.2 -2,-0.2 -4,-0.3 -1,-0.2 0.389 105.3 108.3-114.9 1.0 0.2 40.0 27.7 315 340 A F S < S- 0 0 81 -4,-0.8 -1,-0.1 1,-0.2 -57,-0.0 -0.998 92.0 -6.3-135.1 129.3 -1.2 36.9 26.0 316 341 A P S S+ 0 0 14 0, 0.0 -1,-0.2 0, 0.0 -3,-0.1 -0.999 143.8 30.7 -92.7 0.4 -3.6 35.3 26.7 317 342 A I S > S- 0 0 0 -5,-0.3 3,-0.9 -53,-0.1 -58,-0.1 -0.966 86.3-121.2-117.0 125.5 -4.0 37.4 29.9 318 343 A P T 3 S+ 0 0 83 0, 0.0 -4,-0.2 0, 0.0 -3,-0.1 -0.380 86.8 15.2 -65.4 139.5 -2.9 41.0 29.9 319 344 A G T 3 S+ 0 0 58 1,-0.2 -5,-0.2 -59,-0.1 2,-0.1 0.667 83.3 142.8 81.2 21.4 -0.2 42.2 32.4 320 345 A R < - 0 0 7 -7,-2.4 2,-0.7 -3,-0.9 -1,-0.2 -0.463 52.1-123.9 -85.7 166.6 1.2 38.9 33.6 321 346 A T + 0 0 33 -2,-0.1 -54,-0.3 -51,-0.0 2,-0.2 -0.883 40.1 174.7-112.3 97.7 4.9 38.2 34.5 322 347 A N - 0 0 0 -2,-0.7 -12,-0.1 -15,-0.2 -9,-0.1 -0.584 27.2-155.1-102.7 168.4 5.9 35.3 32.3 323 348 A Y + 0 0 21 -83,-0.2 -16,-0.1 -2,-0.2 -15,-0.1 -0.436 38.8 140.4-139.3 57.9 9.4 33.6 31.9 324 349 A P + 0 0 0 0, 0.0 -84,-1.5 0, 0.0 2,-0.1 0.528 49.1 58.7 -88.9 -10.2 9.3 32.0 28.5 325 350 A L S S- 0 0 0 2,-0.3 11,-0.2 -86,-0.2 12,-0.1 -0.398 84.5 -98.4-120.4-171.9 12.7 32.6 26.9 326 351 A L S S+ 0 0 4 -21,-0.3 8,-2.8 -2,-0.1 11,-0.4 0.638 100.2 56.5 -89.8 -14.7 16.4 32.0 27.3 327 352 A F B S-mN 306 333F 4 -22,-0.7 -20,-2.4 6,-0.2 -2,-0.3 -0.934 77.3-133.8-122.0 140.7 17.4 35.4 28.7 328 353 A D > - 0 0 51 4,-2.8 3,-2.2 -2,-0.4 -20,-0.2 -0.083 40.3 -82.4 -85.3-176.4 16.0 37.0 31.8 329 354 A R T 3 S+ 0 0 89 1,-0.3 -23,-0.1 2,-0.1 -1,-0.1 0.632 131.9 50.8 -67.6 -11.7 14.8 40.6 32.3 330 355 A K T 3 S- 0 0 77 2,-0.2 -1,-0.3 -22,-0.0 -2,-0.0 0.195 121.0-108.6-103.8 13.3 18.3 41.8 32.9 331 356 A L S < S+ 0 0 20 -3,-2.2 -2,-0.1 1,-0.3 -5,-0.0 0.668 74.0 140.5 65.8 23.1 19.5 40.0 29.7 332 357 A Q - 0 0 92 1,-0.1 -4,-2.8 0, 0.0 -1,-0.3 -0.740 60.2-103.2 -94.7 140.1 21.3 37.3 31.7 333 358 A P B -N 327 0F 42 0, 0.0 -6,-0.2 0, 0.0 2,-0.1 -0.393 35.5-138.8 -61.7 136.6 21.2 33.7 30.4 334 359 A K >> - 0 0 8 -8,-2.8 3,-1.2 -2,-0.1 4,-1.1 -0.450 32.5 -93.7 -87.4 167.7 18.8 31.5 32.4 335 360 A D H 3> S+ 0 0 63 1,-0.3 4,-1.9 2,-0.2 3,-0.3 0.870 124.4 63.3 -50.6 -37.8 19.5 27.9 33.4 336 361 A A H 3> S+ 0 0 0 1,-0.2 4,-2.0 2,-0.2 -1,-0.3 0.867 97.1 56.6 -55.1 -41.3 17.8 26.7 30.2 337 362 A Y H <> S+ 0 0 8 -3,-1.2 4,-2.0 -11,-0.4 -1,-0.2 0.910 106.5 48.7 -57.8 -48.5 20.5 28.5 28.0 338 363 A F H X S+ 0 0 99 -4,-1.1 4,-2.6 -3,-0.3 -1,-0.2 0.868 107.8 54.2 -64.2 -35.5 23.3 26.6 29.7 339 364 A R H X S+ 0 0 74 -4,-1.9 4,-1.7 1,-0.2 -1,-0.2 0.916 108.4 50.9 -62.5 -40.0 21.5 23.2 29.3 340 365 A L H X S+ 0 0 0 -4,-2.0 4,-0.7 1,-0.2 -2,-0.2 0.894 111.4 46.5 -63.3 -41.4 21.2 24.0 25.5 341 366 A L H >X S+ 0 0 44 -4,-2.0 4,-2.6 1,-0.2 3,-1.1 0.921 108.6 56.0 -66.8 -41.9 24.9 24.8 25.3 342 367 A D H 3X S+ 0 0 82 -4,-2.6 4,-2.1 1,-0.3 -1,-0.2 0.833 96.2 65.2 -59.2 -35.9 25.9 21.6 27.2 343 368 A L H 3< S+ 0 0 37 -4,-1.7 -1,-0.3 1,-0.2 -2,-0.2 0.852 114.5 31.1 -56.3 -32.0 24.0 19.4 24.7 344 369 A K H X< S+ 0 0 33 -3,-1.1 3,-1.1 -4,-0.7 -2,-0.2 0.839 114.3 57.7 -95.3 -38.3 26.5 20.5 22.1 345 370 A R H 3< S+ 0 0 82 -4,-2.6 -3,-0.2 1,-0.3 -2,-0.2 0.868 117.3 36.4 -57.6 -38.3 29.6 21.0 24.1 346 371 A L T 3< S+ 0 0 112 -4,-2.1 -1,-0.3 -5,-0.2 -2,-0.2 0.270 85.2 136.6-104.9 7.7 29.4 17.5 25.4 347 372 A E < 0 0 99 -3,-1.1 -3,-0.1 -5,-0.1 -4,-0.0 -0.253 360.0 360.0 -60.3 142.7 28.1 15.8 22.2 348 373 A H 0 0 223 0, 0.0 -1,-0.1 0, 0.0 -2,-0.1 -0.899 360.0 360.0-102.9 360.0 29.8 12.4 21.3