==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=18-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER SIGNALING PROTEIN REGULATOR 09-DEC-03 1UTI . COMPND 2 MOLECULE: GRB2-RELATED ADAPTOR PROTEIN 2; . SOURCE 2 ORGANISM_SCIENTIFIC: MUS MUSCULUS; . AUTHOR M.LEWITZKY,M.HARKIOLAKI,M.C.DOMART,S.M.FELLER . 73 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 4975.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 39 53.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 2 2.7 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 22 30.1 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 1.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 6 8.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 8 11.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 0 3 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A V 0 0 47 0, 0.0 3,-0.1 0, 0.0 56,-0.1 0.000 360.0 360.0 360.0 124.2 0.6 11.5 9.6 2 2 A R + 0 0 145 1,-0.3 26,-2.8 54,-0.3 2,-0.3 0.719 360.0 27.2-105.2 -32.5 -1.9 9.3 7.7 3 3 A W E +A 27 0A 132 53,-0.3 53,-2.5 24,-0.2 2,-0.3 -0.988 59.7 175.9-137.5 142.1 0.4 7.4 5.2 4 4 A A E -AB 26 55A 0 22,-1.9 22,-2.9 -2,-0.3 2,-0.4 -0.995 22.7-131.9-147.1 147.9 4.0 6.3 5.3 5 5 A R E -AB 25 54A 133 49,-2.6 49,-2.2 -2,-0.3 20,-0.2 -0.869 28.2-113.7-105.9 133.4 6.2 4.2 3.0 6 6 A A E - B 0 53A 1 18,-3.0 17,-2.5 -2,-0.4 47,-0.3 -0.428 23.7-172.1 -66.6 126.9 8.4 1.3 4.3 7 7 A L S S+ 0 0 79 45,-2.9 2,-0.3 -2,-0.2 46,-0.2 0.700 72.8 14.3 -87.1 -26.9 12.1 2.1 3.9 8 8 A Y S S- 0 0 85 44,-1.0 2,-0.2 13,-0.1 -1,-0.2 -0.954 90.3 -88.6-142.4 158.1 13.1 -1.5 4.9 9 9 A D - 0 0 82 -2,-0.3 2,-0.4 12,-0.2 12,-0.2 -0.521 41.9-159.9 -61.5 136.9 11.6 -4.9 5.4 10 10 A F B -F 20 0B 8 10,-2.7 10,-2.0 -2,-0.2 2,-0.6 -0.994 4.6-150.7-124.7 125.1 10.2 -5.3 8.9 11 11 A E - 0 0 145 -2,-0.4 2,-0.4 8,-0.2 7,-0.1 -0.847 15.4-134.1 -95.1 120.0 9.7 -8.8 10.4 12 12 A A + 0 0 38 -2,-0.6 7,-0.1 1,-0.1 36,-0.1 -0.610 30.9 169.0 -72.5 124.9 6.9 -9.0 13.0 13 13 A L + 0 0 121 -2,-0.4 2,-0.3 5,-0.0 -1,-0.1 0.470 59.2 53.1-116.0 -9.7 8.1 -11.0 15.9 14 14 A E S > S- 0 0 101 1,-0.0 3,-1.9 53,-0.0 -1,-0.0 -0.865 89.0-108.7-126.4 162.3 5.4 -10.3 18.5 15 15 A E T 3 S+ 0 0 203 -2,-0.3 -1,-0.0 1,-0.3 -3,-0.0 0.801 116.5 50.0 -61.0 -31.3 1.6 -10.7 18.3 16 16 A D T 3 S+ 0 0 67 30,-0.1 31,-2.8 2,-0.1 -1,-0.3 0.315 91.1 105.3 -91.7 8.1 1.0 -6.9 18.2 17 17 A E B < -c 47 0A 13 -3,-1.9 2,-0.6 29,-0.3 31,-0.2 -0.666 59.7-143.9 -99.5 145.1 3.5 -6.2 15.4 18 18 A L - 0 0 9 29,-2.6 28,-0.1 -2,-0.3 2,-0.1 -0.920 18.1-155.6-108.3 108.3 2.7 -5.3 11.7 19 19 A G + 0 0 30 -2,-0.6 2,-0.3 -7,-0.1 -8,-0.2 -0.413 19.2 166.1 -78.1 155.0 5.3 -6.8 9.3 20 20 A F B -F 10 0B 11 -10,-2.0 -10,-2.7 -2,-0.1 2,-0.3 -0.982 31.4-116.5-157.9 167.1 5.9 -5.3 5.9 21 21 A R > - 0 0 166 -2,-0.3 3,-1.9 -12,-0.2 -15,-0.2 -0.791 49.9 -82.4-101.7 153.1 8.3 -5.3 2.9 22 22 A S T 3 S+ 0 0 70 -2,-0.3 -15,-0.2 1,-0.2 -13,-0.1 -0.241 116.3 24.9 -49.1 133.2 10.3 -2.3 1.7 23 23 A G T 3 S+ 0 0 18 -17,-2.5 -1,-0.2 1,-0.3 -16,-0.1 0.238 88.0 130.3 92.6 -11.6 8.2 -0.0 -0.5 24 24 A E < - 0 0 52 -3,-1.9 -18,-3.0 -19,-0.1 2,-0.6 -0.380 56.8-126.1 -69.7 150.9 4.8 -1.0 1.0 25 25 A V E -A 5 0A 62 -20,-0.2 2,-0.4 -3,-0.1 -20,-0.2 -0.911 22.9-159.3-107.8 121.6 2.5 1.8 2.0 26 26 A V E -A 4 0A 0 -22,-2.9 -22,-1.9 -2,-0.6 2,-0.6 -0.832 17.7-129.8-102.5 134.7 1.1 1.7 5.6 27 27 A E E -AD 3 40A 54 13,-2.3 13,-2.1 -2,-0.4 2,-0.6 -0.746 29.7-140.2 -75.1 120.3 -2.0 3.5 6.8 28 28 A V E + D 0 39A 0 -26,-2.8 11,-0.3 -2,-0.6 3,-0.1 -0.807 31.7 167.3 -94.2 122.1 -0.8 5.3 10.0 29 29 A L E S+ 0 0 72 9,-2.7 2,-0.4 -2,-0.6 10,-0.2 0.799 72.7 21.8-100.5 -41.1 -3.2 5.2 12.9 30 30 A D E + D 0 38A 54 8,-2.0 8,-1.9 1,-0.1 -1,-0.3 -0.992 50.5 159.1-130.6 130.0 -1.0 6.5 15.7 31 31 A S + 0 0 44 -2,-0.4 6,-0.1 6,-0.2 -1,-0.1 0.120 57.5 93.0-124.9 16.4 2.3 8.5 15.3 32 32 A S + 0 0 84 4,-0.1 5,-0.1 2,-0.0 -1,-0.0 0.781 67.0 81.0 -81.6 -29.6 2.4 10.0 18.8 33 33 A N S S- 0 0 15 3,-0.2 17,-0.1 1,-0.1 39,-0.1 -0.689 74.6-151.9 -72.0 121.7 4.6 7.1 20.2 34 34 A P S S+ 0 0 85 0, 0.0 -1,-0.1 0, 0.0 3,-0.1 0.713 88.2 37.1 -73.2 -18.5 8.2 8.1 19.0 35 35 A S S S+ 0 0 11 34,-0.3 15,-2.2 1,-0.3 2,-0.5 0.861 122.8 28.0 -97.3 -49.9 9.5 4.5 18.8 36 36 A W E - E 0 49A 0 33,-0.4 -1,-0.3 13,-0.2 -3,-0.2 -0.973 65.8-160.9-126.6 118.3 6.6 2.4 17.6 37 37 A W E - E 0 48A 29 11,-2.4 11,-2.4 -2,-0.5 2,-0.4 -0.614 16.7-130.4 -91.8 155.3 3.7 3.6 15.3 38 38 A T E +DE 30 47A 42 -8,-1.9 -9,-2.7 9,-0.2 -8,-2.0 -0.908 42.9 141.7-105.7 136.4 0.4 1.9 14.9 39 39 A G E -DE 28 46A 0 7,-2.6 7,-2.1 -2,-0.4 2,-0.4 -0.892 39.0-109.6-159.5-173.1 -0.9 1.2 11.5 40 40 A R E +DE 27 45A 91 -13,-2.1 -13,-2.3 -2,-0.3 2,-0.3 -0.989 25.3 161.5-139.5 141.1 -2.6 -1.0 9.0 41 41 A L E > S+ E 0 44A 18 3,-2.1 3,-1.8 -2,-0.4 -15,-0.1 -0.928 77.6 8.9-156.2 135.1 -1.7 -3.1 6.0 42 42 A H T 3 S- 0 0 119 -2,-0.3 3,-0.1 1,-0.3 -1,-0.0 0.854 129.8 -65.9 59.5 36.6 -3.7 -6.0 4.3 43 43 A N T 3 S+ 0 0 150 1,-0.2 2,-0.4 0, 0.0 -1,-0.3 0.556 111.9 128.3 57.7 13.5 -6.5 -4.9 6.7 44 44 A K E < - E 0 41A 137 -3,-1.8 -3,-2.1 2,-0.0 2,-0.3 -0.798 50.8-143.3-102.0 139.2 -4.2 -6.1 9.5 45 45 A L E + E 0 40A 112 -2,-0.4 2,-0.3 -5,-0.2 -5,-0.2 -0.751 34.7 127.3-100.0 144.4 -3.4 -3.9 12.5 46 46 A G E - E 0 39A 7 -7,-2.1 -7,-2.6 -2,-0.3 2,-0.3 -0.979 51.0 -92.6-178.1 174.2 -0.1 -3.7 14.3 47 47 A L E +cE 17 38A 25 -31,-2.8 -29,-2.6 -2,-0.3 -9,-0.2 -0.741 39.3 173.1 -96.1 147.6 2.8 -1.8 15.7 48 48 A F E - E 0 37A 0 -11,-2.4 -11,-2.4 -2,-0.3 2,-0.2 -0.973 40.8 -78.5-149.7 159.7 6.0 -1.1 13.6 49 49 A P E > - E 0 36A 0 0, 0.0 3,-1.6 0, 0.0 -13,-0.2 -0.421 27.2-146.7 -66.6 127.6 9.2 1.0 14.0 50 50 A A G > S+ 0 0 17 -15,-2.2 3,-1.4 1,-0.3 -14,-0.1 0.861 101.3 58.1 -56.3 -36.1 8.7 4.7 13.2 51 51 A N G 3 S+ 0 0 66 -16,-0.5 -1,-0.3 1,-0.3 -15,-0.1 0.541 94.4 66.4 -76.6 -6.3 12.3 4.7 11.9 52 52 A Y G < S+ 0 0 17 -3,-1.6 -45,-2.9 -45,-0.1 -44,-1.0 0.441 101.2 53.9 -91.9 -0.9 11.4 2.0 9.4 53 53 A V E < -B 6 0A 8 -3,-1.4 -47,-0.2 -47,-0.3 -28,-0.1 -0.908 67.0-142.5-130.5 160.8 9.0 4.3 7.4 54 54 A A E -B 5 0A 37 -49,-2.2 -49,-2.6 -2,-0.3 -3,-0.1 -0.988 31.6-121.4-119.4 115.1 9.1 7.7 5.7 55 55 A P E -B 4 0A 59 0, 0.0 2,-0.7 0, 0.0 -51,-0.3 -0.261 21.5-131.2 -52.6 141.7 5.9 9.7 6.1 56 56 A M 0 0 74 -53,-2.5 -53,-0.3 0, 0.0 -54,-0.3 -0.900 360.0 360.0-102.7 106.6 4.3 10.6 2.8 57 57 A M 0 0 179 -2,-0.7 -53,-0.0 -56,-0.1 0, 0.0 -0.822 360.0 360.0-168.0 360.0 3.4 14.4 2.7 58 !* 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 59 1 D G 0 0 133 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 -47.5 24.0 -1.3 3.7 60 2 D Q - 0 0 188 1,-0.1 0, 0.0 0, 0.0 0, 0.0 -0.339 360.0-111.7 -75.7 141.5 22.4 -2.9 6.7 61 3 D P - 0 0 68 0, 0.0 -1,-0.1 0, 0.0 3,-0.1 -0.219 41.5 -95.7 -62.6 157.9 19.0 -1.7 8.0 62 4 D P - 0 0 45 0, 0.0 2,-0.0 0, 0.0 -54,-0.0 -0.210 47.8 -84.5 -70.6 165.3 18.8 0.2 11.3 63 5 D L - 0 0 153 1,-0.1 -12,-0.1 -12,-0.0 0, 0.0 -0.318 37.1-117.7 -64.3 150.8 18.0 -1.4 14.6 64 6 D V - 0 0 40 -3,-0.1 3,-0.1 1,-0.1 -1,-0.1 -0.742 39.4-110.0 -79.9 135.9 14.4 -2.0 15.7 65 7 D P - 0 0 20 0, 0.0 -1,-0.1 0, 0.0 5,-0.1 -0.217 49.8 -70.9 -62.9 161.1 13.7 -0.1 18.9 66 8 D P > - 0 0 62 0, 0.0 3,-1.6 0, 0.0 4,-0.1 -0.270 39.7-131.0 -51.9 135.5 13.3 -2.0 22.2 67 9 D R G > S+ 0 0 64 1,-0.3 3,-1.8 2,-0.2 4,-0.3 0.771 103.3 70.6 -60.5 -26.6 10.0 -3.9 22.2 68 10 D K G > S+ 0 0 153 1,-0.3 3,-1.0 2,-0.2 -1,-0.3 0.749 86.2 68.3 -64.2 -20.9 9.2 -2.4 25.7 69 11 D E G < S+ 0 0 32 -3,-1.6 -33,-0.4 1,-0.2 -34,-0.3 0.496 74.8 83.4 -79.6 -2.5 8.7 1.0 24.0 70 12 D K G < S+ 0 0 20 -3,-1.8 -1,-0.2 -35,-0.1 -2,-0.2 0.838 80.0 81.5 -64.9 -32.8 5.5 -0.3 22.2 71 13 D M S < S- 0 0 145 -3,-1.0 3,-0.4 -4,-0.3 -35,-0.1 -0.239 102.7 -77.3 -65.0 163.3 3.7 0.6 25.5 72 14 D R S S+ 0 0 234 1,-0.2 -1,-0.1 -39,-0.1 -2,-0.1 -0.201 114.9 39.9 -67.9 155.7 2.8 4.2 26.1 73 15 D G 0 0 79 -3,-0.1 -1,-0.2 -4,-0.0 -2,-0.1 0.690 360.0 360.0 77.8 24.3 5.3 6.9 27.1 74 16 D K 0 0 115 -3,-0.4 -3,-0.1 -5,-0.2 -41,-0.0 -0.402 360.0 360.0 54.9 360.0 7.7 5.2 24.7