==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=18-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER CHAPERONE 02-MAR-04 1UY6 . COMPND 2 MOLECULE: HEAT SHOCK PROTEIN HSP 90-ALPHA; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR L.WRIGHT,X.BARRIL,B.DYMOCK,L.SHERIDAN,A.SURGENOR,M.BESWICK, . 207 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 10665.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 158 76.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 4 1.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 41 19.8 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 14 6.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 32 15.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 59 28.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 5 2.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 1 0 0 0 0 0 1 1 0 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 0 2 0 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 17 A V 0 0 119 0, 0.0 2,-0.4 0, 0.0 156,-0.2 0.000 360.0 360.0 360.0 114.2 8.4 27.6 34.9 2 18 A E E -A 156 0A 91 154,-2.4 154,-2.1 2,-0.0 2,-0.4 -0.883 360.0-153.8-100.1 136.6 11.2 24.9 34.7 3 19 A T E -A 155 0A 97 -2,-0.4 2,-0.3 152,-0.2 152,-0.2 -0.938 14.1-175.4-112.0 133.2 13.3 24.7 31.5 4 20 A F E -A 154 0A 48 150,-3.2 150,-2.2 -2,-0.4 2,-0.4 -0.896 23.7-124.2-127.0 154.8 14.9 21.5 30.4 5 21 A A E -A 153 0A 83 -2,-0.3 148,-0.3 148,-0.2 2,-0.1 -0.803 29.2-124.3 -92.5 133.6 17.3 20.3 27.7 6 22 A F - 0 0 16 146,-2.0 5,-0.0 -2,-0.4 -1,-0.0 -0.493 39.9 -92.6 -60.7 150.3 16.2 17.5 25.4 7 23 A Q >> - 0 0 67 -2,-0.1 4,-2.1 1,-0.1 3,-0.8 -0.300 44.7-106.8 -56.6 143.8 18.6 14.6 25.3 8 24 A A H 3> S+ 0 0 75 1,-0.2 4,-2.2 2,-0.2 5,-0.1 0.865 117.7 54.0 -49.2 -40.9 20.9 15.1 22.4 9 25 A E H 3> S+ 0 0 65 1,-0.2 4,-2.4 2,-0.2 -1,-0.2 0.847 108.3 49.3 -66.5 -35.5 19.3 12.4 20.2 10 26 A I H <> S+ 0 0 3 -3,-0.8 4,-2.6 2,-0.2 -1,-0.2 0.880 109.4 51.7 -68.7 -41.4 15.8 13.9 20.6 11 27 A A H X S+ 0 0 26 -4,-2.1 4,-2.4 2,-0.2 -2,-0.2 0.917 110.9 49.3 -59.3 -41.0 17.1 17.3 19.7 12 28 A Q H X S+ 0 0 126 -4,-2.2 4,-2.3 -5,-0.2 -2,-0.2 0.931 110.5 49.7 -65.1 -45.9 18.6 15.8 16.5 13 29 A L H X S+ 0 0 0 -4,-2.4 4,-2.5 2,-0.2 -1,-0.2 0.923 110.5 50.7 -55.9 -47.1 15.4 14.0 15.7 14 30 A M H X S+ 0 0 2 -4,-2.6 4,-2.5 1,-0.2 -2,-0.2 0.943 110.4 48.5 -61.0 -45.4 13.4 17.3 16.1 15 31 A S H X S+ 0 0 58 -4,-2.4 4,-2.5 1,-0.2 5,-0.2 0.886 109.8 52.6 -60.4 -41.4 15.8 19.2 13.8 16 32 A L H X S+ 0 0 37 -4,-2.3 4,-2.5 2,-0.2 -1,-0.2 0.905 110.0 48.5 -61.9 -41.4 15.5 16.4 11.2 17 33 A I H < S+ 0 0 1 -4,-2.5 -2,-0.2 1,-0.2 -1,-0.2 0.911 117.1 41.8 -65.6 -41.1 11.7 16.6 11.3 18 34 A I H < S+ 0 0 66 -4,-2.5 -2,-0.2 -5,-0.2 -1,-0.2 0.837 123.1 38.2 -67.5 -35.9 11.8 20.5 10.9 19 35 A N H < S+ 0 0 123 -4,-2.5 -2,-0.2 -5,-0.2 -3,-0.2 0.819 90.1 94.7 -93.7 -37.8 14.6 20.5 8.3 20 36 A T S < S- 0 0 63 -4,-2.5 2,-0.6 -5,-0.2 -4,-0.0 -0.350 77.5-119.8 -60.2 134.3 14.0 17.6 6.0 21 37 A F + 0 0 182 -2,-0.1 2,-0.3 2,-0.0 -1,-0.1 -0.621 52.5 149.1 -69.4 119.4 12.0 18.3 2.8 22 38 A Y - 0 0 38 -2,-0.6 3,-0.1 1,-0.1 -2,-0.0 -0.825 29.5-169.1-159.5 110.7 9.0 16.1 3.1 23 39 A S S S+ 0 0 90 -2,-0.3 2,-2.4 1,-0.2 3,-0.2 0.783 71.0 82.5 -80.6 -27.2 5.6 17.0 1.5 24 40 A N > + 0 0 66 1,-0.2 3,-1.1 2,-0.1 -1,-0.2 -0.333 50.0 147.1 -77.3 56.4 3.3 14.4 3.1 25 41 A K T > + 0 0 39 -2,-2.4 3,-1.9 1,-0.2 -1,-0.2 0.663 47.4 85.8 -65.8 -21.1 2.9 16.3 6.4 26 42 A E T >> + 0 0 19 1,-0.3 3,-1.6 -3,-0.2 4,-0.6 0.672 67.4 81.0 -59.5 -17.8 -0.6 15.1 7.0 27 43 A I H <> S+ 0 0 1 -3,-1.1 4,-1.6 1,-0.3 -1,-0.3 0.672 72.2 80.7 -67.2 -14.1 0.6 11.9 8.7 28 44 A F H <> S+ 0 0 1 -3,-1.9 4,-2.0 1,-0.2 -1,-0.3 0.887 88.1 55.6 -54.4 -37.2 1.1 14.0 12.0 29 45 A L H <> S+ 0 0 1 -3,-1.6 4,-2.8 1,-0.2 5,-0.2 0.932 104.8 48.7 -71.6 -42.1 -2.7 13.7 12.7 30 46 A R H X S+ 0 0 60 -4,-0.6 4,-2.6 1,-0.2 -1,-0.2 0.877 110.4 54.2 -62.5 -34.5 -2.9 9.9 12.6 31 47 A E H X S+ 0 0 14 -4,-1.6 4,-2.2 2,-0.2 -1,-0.2 0.920 111.8 42.8 -67.4 -39.8 0.2 9.8 14.9 32 48 A L H X S+ 0 0 3 -4,-2.0 4,-2.2 2,-0.2 -2,-0.2 0.904 114.7 49.1 -75.5 -40.2 -1.5 12.0 17.5 33 49 A I H X S+ 0 0 0 -4,-2.8 4,-2.8 2,-0.2 -2,-0.2 0.898 110.2 52.4 -62.8 -40.8 -4.8 10.3 17.3 34 50 A S H X S+ 0 0 43 -4,-2.6 4,-2.6 -5,-0.2 -2,-0.2 0.908 108.0 51.2 -59.7 -44.1 -3.1 6.9 17.6 35 51 A N H X S+ 0 0 62 -4,-2.2 4,-2.0 2,-0.2 -2,-0.2 0.921 111.3 48.0 -59.9 -41.2 -1.3 8.2 20.8 36 52 A S H X S+ 0 0 4 -4,-2.2 4,-2.3 2,-0.2 -2,-0.2 0.923 110.8 51.2 -62.7 -46.1 -4.7 9.3 22.2 37 53 A S H X S+ 0 0 14 -4,-2.8 4,-2.7 1,-0.2 -2,-0.2 0.909 110.1 48.7 -57.1 -46.9 -6.3 5.9 21.3 38 54 A D H X S+ 0 0 92 -4,-2.6 4,-1.8 1,-0.2 -1,-0.2 0.881 111.6 50.5 -58.7 -40.1 -3.4 4.1 23.1 39 55 A A H X S+ 0 0 17 -4,-2.0 4,-1.9 2,-0.2 41,-1.8 0.847 110.9 47.9 -69.3 -36.8 -3.9 6.4 26.2 40 56 A L H X S+ 0 0 0 -4,-2.3 4,-2.6 39,-0.3 -2,-0.2 0.923 110.4 51.9 -70.5 -42.1 -7.7 5.7 26.2 41 57 A D H X S+ 0 0 60 -4,-2.7 4,-3.0 1,-0.2 -2,-0.2 0.872 109.0 54.2 -53.3 -43.2 -7.0 1.9 25.9 42 58 A K H X S+ 0 0 116 -4,-1.8 4,-2.7 2,-0.2 -2,-0.2 0.961 111.9 38.5 -63.2 -51.9 -4.7 2.2 28.9 43 59 A I H X S+ 0 0 0 -4,-1.9 4,-2.3 2,-0.2 -2,-0.2 0.911 116.1 54.6 -69.1 -37.0 -7.1 3.9 31.3 44 60 A R H X S+ 0 0 116 -4,-2.6 4,-0.8 1,-0.2 -2,-0.2 0.964 112.0 44.8 -56.2 -48.9 -10.0 1.6 30.0 45 61 A Y H >X S+ 0 0 168 -4,-3.0 3,-0.8 1,-0.2 4,-0.5 0.906 112.4 50.2 -63.2 -46.9 -7.8 -1.4 30.8 46 62 A E H >X S+ 0 0 44 -4,-2.7 3,-0.9 1,-0.2 4,-0.5 0.843 104.5 59.3 -62.3 -33.8 -6.7 -0.2 34.2 47 63 A S H 3< S+ 0 0 15 -4,-2.3 -1,-0.2 1,-0.2 -2,-0.2 0.698 87.4 74.0 -73.3 -19.2 -10.3 0.6 35.2 48 64 A L H << S+ 0 0 136 -3,-0.8 -1,-0.2 -4,-0.8 -2,-0.2 0.823 110.6 30.5 -55.8 -35.8 -11.4 -3.1 34.8 49 65 A T H << S+ 0 0 121 -3,-0.9 -1,-0.2 -4,-0.5 -2,-0.2 0.440 134.7 29.0-104.5 0.7 -9.5 -3.8 38.0 50 66 A D >< - 0 0 62 -4,-0.5 3,-2.0 -3,-0.1 -1,-0.2 -0.577 61.2-175.4-158.0 85.0 -10.0 -0.5 39.8 51 67 A P G > S+ 0 0 96 0, 0.0 3,-1.7 0, 0.0 -4,-0.1 0.705 78.7 75.8 -60.6 -21.0 -13.2 1.3 38.8 52 68 A S G > S+ 0 0 62 1,-0.3 3,-1.9 2,-0.2 4,-0.3 0.707 76.1 77.8 -64.8 -18.8 -12.2 4.3 40.9 53 69 A K G < S+ 0 0 50 -3,-2.0 3,-0.4 1,-0.3 -1,-0.3 0.711 91.8 54.1 -59.8 -22.6 -9.7 5.2 38.1 54 70 A L G X S+ 0 0 30 -3,-1.7 3,-2.4 -4,-0.2 -1,-0.3 0.374 75.1 96.6 -94.0 5.6 -12.7 6.6 36.2 55 71 A D T < S+ 0 0 131 -3,-1.9 -1,-0.2 1,-0.3 3,-0.2 0.795 80.3 62.2 -59.3 -26.2 -14.0 8.9 39.0 56 72 A S T 3 S- 0 0 36 -3,-0.4 -1,-0.3 -4,-0.3 -2,-0.1 0.441 133.1 -37.5 -82.3 -4.4 -12.0 11.6 37.1 57 73 A G < - 0 0 29 -3,-2.4 -1,-0.3 108,-0.1 -2,-0.1 -0.143 42.5-150.2 149.7 131.9 -14.4 11.0 34.2 58 74 A K + 0 0 169 -3,-0.2 2,-0.2 -2,-0.1 -3,-0.1 0.727 68.9 97.5 -83.2 -29.7 -16.2 8.0 32.6 59 75 A E - 0 0 152 -5,-0.1 2,-0.6 1,-0.1 0, 0.0 -0.461 54.8-162.6 -73.5 133.5 -16.4 9.3 29.0 60 76 A L + 0 0 35 -2,-0.2 2,-0.3 17,-0.1 19,-0.1 -0.911 35.5 123.1-120.5 103.0 -13.6 8.0 26.6 61 77 A H - 0 0 29 -2,-0.6 17,-1.4 139,-0.2 2,-0.4 -0.901 50.6-125.2-154.9 170.4 -13.3 10.1 23.5 62 78 A I E -Bc 77 202A 0 139,-2.5 141,-2.8 -2,-0.3 2,-0.4 -0.999 20.6-164.9-127.3 133.1 -11.1 12.2 21.2 63 79 A N E -Bc 76 203A 26 13,-2.5 13,-3.3 -2,-0.4 2,-0.5 -0.939 7.5-156.4-118.9 141.4 -12.0 15.8 20.1 64 80 A L E -Bc 75 204A 0 139,-3.1 141,-2.6 -2,-0.4 11,-0.2 -0.986 16.6-174.3-117.2 119.7 -10.3 17.7 17.3 65 81 A I E -B 74 0A 50 9,-3.0 9,-2.7 -2,-0.5 2,-0.3 -0.924 7.3-168.7-128.3 104.0 -10.6 21.4 17.8 66 82 A P E -B 73 0A 8 0, 0.0 2,-0.3 0, 0.0 7,-0.2 -0.668 2.3-174.1 -87.3 148.1 -9.5 24.0 15.2 67 83 A N E >> -B 72 0A 47 5,-2.4 5,-2.1 -2,-0.3 4,-0.8 -0.824 9.0-172.8-144.8 103.8 -9.3 27.6 16.1 68 84 A K T 45S+ 0 0 103 -2,-0.3 -1,-0.1 1,-0.2 5,-0.0 0.799 84.2 59.1 -69.9 -29.4 -8.5 30.0 13.2 69 85 A Q T 45S+ 0 0 154 1,-0.2 -1,-0.2 2,-0.1 -2,-0.0 0.892 117.6 30.9 -65.6 -40.0 -8.1 33.0 15.5 70 86 A D T 45S- 0 0 112 -3,-0.3 -1,-0.2 2,-0.1 -2,-0.2 0.487 105.3-127.7 -92.6 -9.8 -5.3 31.4 17.6 71 87 A R T <5 + 0 0 71 -4,-0.8 103,-1.9 1,-0.2 2,-0.3 0.928 63.7 135.7 52.9 49.6 -4.0 29.4 14.6 72 88 A T E < -BD 67 173A 9 -5,-2.1 -5,-2.4 101,-0.2 2,-0.5 -0.944 46.7-161.1-124.1 148.3 -4.2 26.2 16.6 73 89 A L E -BD 66 172A 1 99,-1.5 99,-2.6 -2,-0.3 2,-0.5 -0.995 20.5-161.5-121.9 122.4 -5.4 22.7 16.1 74 90 A T E -BD 65 171A 20 -9,-2.7 -9,-3.0 -2,-0.5 2,-0.6 -0.893 10.8-158.4-111.9 130.2 -6.0 20.9 19.4 75 91 A I E -BD 64 170A 0 95,-2.5 95,-2.7 -2,-0.5 2,-0.4 -0.963 20.4-169.8-105.9 113.4 -6.2 17.1 19.8 76 92 A V E +BD 63 169A 13 -13,-3.3 -13,-2.5 -2,-0.6 2,-0.3 -0.877 10.4 170.0-106.4 135.6 -8.1 16.4 23.0 77 93 A D E -BD 62 168A 6 91,-2.4 91,-1.3 -2,-0.4 -15,-0.2 -0.961 34.6-144.2-134.8 162.0 -8.4 13.0 24.7 78 94 A T + 0 0 23 -17,-1.4 89,-0.2 -2,-0.3 -16,-0.1 -0.186 60.9 129.1-112.4 39.3 -9.7 11.7 28.1 79 95 A G S S- 0 0 0 89,-0.1 -39,-0.3 -18,-0.1 -40,-0.1 0.094 80.2 -63.6 -73.4-165.6 -7.1 8.9 28.2 80 96 A I - 0 0 15 -41,-1.8 59,-0.5 -44,-0.2 87,-0.2 0.726 69.1-148.6 -60.0 -25.7 -4.7 8.1 31.0 81 97 A G - 0 0 4 85,-0.2 2,-0.4 57,-0.2 57,-0.2 -0.123 18.0 -85.6 78.0 177.5 -2.8 11.4 30.9 82 98 A M - 0 0 42 85,-0.4 56,-0.4 62,-0.1 62,-0.2 -0.969 29.0-134.0-130.5 138.1 0.9 11.9 31.7 83 99 A T > - 0 0 26 -2,-0.4 4,-2.3 54,-0.1 5,-0.2 -0.397 32.5-106.0 -79.3 167.8 2.7 12.5 35.0 84 100 A K H > S+ 0 0 67 1,-0.2 4,-2.8 2,-0.2 5,-0.3 0.933 123.6 55.3 -58.1 -42.6 5.4 15.1 35.6 85 101 A A H >>S+ 0 0 46 1,-0.2 5,-2.5 2,-0.2 4,-2.4 0.856 106.5 50.0 -60.7 -41.7 7.9 12.3 35.6 86 102 A D H 4>S+ 0 0 41 3,-0.2 5,-1.8 4,-0.2 6,-0.5 0.939 113.0 48.0 -51.6 -54.4 6.7 11.1 32.2 87 103 A L H <5S+ 0 0 16 -4,-2.3 -2,-0.2 1,-0.2 -1,-0.2 0.891 123.6 28.8 -64.7 -40.9 7.0 14.7 30.9 88 104 A I H <5S- 0 0 34 -4,-2.8 -1,-0.2 -5,-0.2 -3,-0.2 0.889 137.0 -2.7 -89.2 -41.2 10.5 15.4 32.2 89 105 A N T X5S+ 0 0 91 -4,-2.4 4,-2.3 -5,-0.3 -3,-0.2 0.785 115.5 53.8-118.0 -57.1 12.3 12.0 32.3 90 106 A N H > S+ 0 0 15 -6,-0.5 4,-0.6 2,-0.2 -2,-0.2 0.892 109.4 51.2 -57.9 -42.8 12.5 10.9 26.9 93 109 A T H >X S+ 0 0 84 -4,-2.3 3,-0.8 1,-0.2 4,-0.5 0.930 113.9 42.2 -64.8 -48.0 14.3 7.8 28.2 94 110 A I H >X S+ 0 0 121 -4,-2.3 4,-0.9 1,-0.2 3,-0.7 0.906 111.5 58.6 -62.0 -39.4 12.1 5.3 26.3 95 111 A A H 3X S+ 0 0 11 -4,-2.6 4,-2.1 1,-0.2 -1,-0.2 0.559 87.0 76.8 -68.0 -13.9 12.3 7.6 23.2 96 112 A K H < S+ 0 0 103 -4,-2.2 3,-2.2 -5,-0.2 -1,-0.2 0.940 111.0 51.0 -58.5 -55.4 19.1 4.4 11.1 105 121 A A H 3<>S+ 0 0 24 -4,-3.0 5,-2.5 1,-0.3 -2,-0.2 0.874 91.4 75.3 -53.5 -38.9 15.9 3.3 9.2 106 122 A L T 3<5S+ 0 0 35 -4,-2.8 2,-0.5 3,-0.2 -1,-0.3 0.725 97.8 55.4 -56.1 -11.9 15.8 6.7 7.5 107 123 A Q T < 5S+ 0 0 147 -3,-2.2 -1,-0.2 -4,-0.3 4,-0.1 -0.928 90.7 57.2-121.1 118.0 18.8 5.1 5.5 108 124 A A T 5S- 0 0 104 -2,-0.5 -1,-0.2 2,-0.1 -2,-0.1 -0.084 135.8 -92.7 126.8 1.7 17.7 1.9 4.0 109 125 A G T 5S+ 0 0 63 -3,-0.2 -3,-0.2 1,-0.1 -2,-0.2 0.729 72.7 161.0 59.1 37.8 15.4 4.5 2.8 110 126 A A < - 0 0 16 -5,-2.5 2,-0.3 -8,-0.1 -1,-0.1 -0.376 32.8-134.1 -67.7 163.6 12.5 4.4 5.3 111 127 A D > - 0 0 62 -2,-0.1 3,-2.3 -4,-0.1 4,-0.1 -0.830 20.9 -98.9-120.1 171.8 10.5 7.6 5.1 112 128 A I G > S+ 0 0 7 1,-0.3 3,-2.2 -2,-0.3 4,-0.2 0.766 113.8 71.2 -57.3 -30.8 9.2 10.0 7.7 113 129 A S G 3 S+ 0 0 27 1,-0.3 3,-0.5 2,-0.1 -1,-0.3 0.656 90.5 63.6 -60.8 -12.0 5.6 8.5 7.5 114 130 A M G X + 0 0 60 -3,-2.3 3,-1.9 1,-0.2 4,-0.3 0.438 68.3 107.3 -93.9 3.9 7.1 5.4 9.3 115 131 A I G X > + 0 0 0 -3,-2.2 3,-1.9 1,-0.3 5,-1.1 0.774 65.6 68.1 -50.1 -33.6 7.9 7.3 12.4 116 132 A G G > 5S+ 0 0 29 -3,-0.5 3,-1.4 1,-0.3 -1,-0.3 0.800 89.0 64.4 -65.9 -27.1 5.1 5.8 14.4 117 133 A Q G < 5S+ 0 0 149 -3,-1.9 -1,-0.3 1,-0.3 -2,-0.2 0.618 100.1 54.0 -70.5 -9.5 6.8 2.3 14.4 118 134 A F G < 5S- 0 0 48 -3,-1.9 -1,-0.3 -4,-0.3 -2,-0.2 0.331 113.3-114.0-107.5 4.2 9.6 3.7 16.4 119 135 A G T < 5S+ 0 0 69 -3,-1.4 3,-0.2 -4,-0.1 -3,-0.2 0.572 95.3 95.5 74.6 15.1 7.5 5.1 19.3 120 136 A V > < + 0 0 3 -5,-1.1 3,-1.6 -22,-0.1 4,-0.3 0.081 34.6 123.9-124.1 23.1 8.3 8.8 18.5 121 137 A G G > + 0 0 2 1,-0.3 3,-1.6 -6,-0.2 4,-0.3 0.754 62.3 76.7 -55.2 -26.9 5.3 9.7 16.3 122 138 A F G > S+ 0 0 41 1,-0.2 3,-2.4 2,-0.2 -1,-0.3 0.904 86.5 60.3 -46.3 -43.9 4.6 12.6 18.8 123 139 A Y G X S+ 0 0 24 -3,-1.6 3,-2.0 1,-0.3 -1,-0.2 0.680 82.0 80.5 -68.6 -12.9 7.5 14.5 17.2 124 140 A S G X S+ 0 0 0 -3,-1.6 3,-2.2 -4,-0.3 4,-0.4 0.714 72.1 81.5 -62.4 -18.3 5.7 14.4 13.9 125 141 A A G X> S+ 0 0 0 -3,-2.4 4,-2.3 -4,-0.3 3,-1.6 0.833 81.0 66.1 -51.5 -34.4 3.7 17.4 15.4 126 142 A Y G <4 S+ 0 0 1 -3,-2.0 -1,-0.3 1,-0.3 -2,-0.2 0.519 81.0 74.9 -72.5 -7.0 6.8 19.5 14.3 127 143 A L G <4 S+ 0 0 2 -3,-2.2 -1,-0.3 -102,-0.1 -2,-0.2 0.787 119.8 12.7 -61.8 -33.1 6.0 18.8 10.6 128 144 A V T <4 S+ 0 0 0 -3,-1.6 47,-3.0 -4,-0.4 2,-0.4 0.610 116.4 74.5-122.6 -20.7 3.2 21.3 11.0 129 145 A A E < -E 174 0A 2 -4,-2.3 45,-0.3 45,-0.3 3,-0.1 -0.840 47.6-165.7-108.6 138.6 3.6 23.1 14.3 130 146 A E E S+ 0 0 107 43,-2.6 2,-0.3 -2,-0.4 44,-0.1 0.721 90.2 14.7 -84.7 -24.1 6.1 25.9 15.2 131 147 A K E -E 173 0A 66 42,-1.2 42,-2.9 -6,-0.1 2,-0.4 -0.987 69.6-158.2-146.9 145.6 5.3 25.3 18.9 132 148 A V E -EF 172 148A 0 16,-2.1 16,-2.3 -2,-0.3 2,-0.4 -0.993 4.7-168.2-131.4 132.7 3.4 22.5 20.7 133 149 A T E -EF 171 147A 13 38,-2.2 38,-3.4 -2,-0.4 2,-0.6 -0.985 4.6-162.4-119.7 130.2 1.8 22.8 24.1 134 150 A V E -EF 170 146A 4 12,-3.2 12,-2.8 -2,-0.4 2,-0.5 -0.962 4.1-169.4-121.6 115.8 0.6 19.8 25.9 135 151 A I E +EF 169 145A 17 34,-2.9 34,-3.4 -2,-0.6 2,-0.3 -0.906 23.0 167.9 -99.1 129.6 -1.9 20.1 28.8 136 152 A T E -EF 168 144A 0 8,-2.3 8,-2.4 -2,-0.5 2,-0.4 -0.995 25.4-169.6-150.8 144.9 -2.2 16.8 30.7 137 153 A K E -EF 167 143A 41 30,-3.2 30,-2.7 -2,-0.3 2,-0.3 -0.975 6.5-170.7-139.8 117.5 -3.6 15.4 33.9 138 154 A H > - 0 0 24 4,-0.5 3,-2.0 -2,-0.4 -57,-0.2 -0.847 34.9-116.7-102.9 146.5 -2.9 11.9 35.2 139 155 A N T 3 S+ 0 0 49 -59,-0.5 -1,-0.1 -2,-0.3 -58,-0.1 0.822 113.5 49.8 -45.5 -39.7 -4.9 10.5 38.2 140 156 A D T 3 S+ 0 0 127 2,-0.1 -1,-0.3 -3,-0.0 2,-0.2 0.354 115.5 34.4 -86.7 10.3 -1.8 10.2 40.3 141 157 A D S < S- 0 0 42 -3,-2.0 2,-0.1 1,-0.1 -58,-0.0 -0.797 84.2 -81.2-154.3-179.8 -0.5 13.8 39.7 142 158 A E - 0 0 125 -2,-0.2 -4,-0.5 1,-0.1 2,-0.4 -0.354 53.7 -85.6 -90.6 173.5 -1.3 17.4 39.1 143 159 A Q E -F 137 0A 20 16,-0.2 16,-3.2 -6,-0.2 2,-0.3 -0.696 53.5-171.7 -82.8 128.5 -2.3 19.2 35.9 144 160 A Y E -FG 136 158A 17 -8,-2.4 -8,-2.3 -2,-0.4 2,-0.5 -0.866 23.0-146.4-122.3 151.2 0.8 20.2 33.8 145 161 A A E -FG 135 157A 10 12,-3.1 12,-1.9 -2,-0.3 2,-0.4 -0.990 16.8-173.2-113.7 123.5 1.7 22.2 30.8 146 162 A W E +FG 134 156A 13 -12,-2.8 -12,-3.2 -2,-0.5 2,-0.3 -0.881 11.2 177.5-102.5 147.3 4.6 21.0 28.7 147 163 A E E +FG 133 155A 45 8,-2.1 8,-2.8 -2,-0.4 2,-0.3 -0.996 10.8 168.4-152.2 145.5 5.7 23.2 25.9 148 164 A S E -F 132 0A 5 -16,-2.3 -16,-2.1 -2,-0.3 6,-0.1 -0.916 26.8-175.2-157.9 138.9 8.4 23.3 23.2 149 165 A S - 0 0 72 1,-0.5 2,-0.1 4,-0.3 5,-0.1 -0.011 58.1-120.5-105.4 23.6 9.3 25.2 20.1 150 166 A A S > S+ 0 0 11 3,-0.4 3,-1.0 1,-0.1 -1,-0.5 -0.482 71.2 131.3 65.2-143.0 12.2 22.9 19.6 151 167 A G T 3 S- 0 0 82 1,-0.2 -1,-0.1 -140,-0.1 3,-0.1 0.706 101.6 -64.9 67.2 16.4 15.7 24.5 19.6 152 168 A G T 3 S+ 0 0 27 1,-0.2 -146,-2.0 -141,-0.1 2,-0.3 0.395 113.3 79.7 93.5 -5.0 16.8 21.9 22.2 153 169 A S E < -A 5 0A 50 -3,-1.0 -3,-0.4 -148,-0.3 -4,-0.3 -0.935 46.4-173.1-136.0 162.1 14.7 22.8 25.1 154 170 A F E -A 4 0A 12 -150,-2.2 -150,-3.2 -2,-0.3 2,-0.3 -0.957 16.2-137.6-142.2 161.6 11.2 22.4 26.6 155 171 A T E -AG 3 147A 25 -8,-2.8 -8,-2.1 -2,-0.3 2,-0.3 -0.875 9.8-167.1-118.9 159.7 9.4 23.8 29.6 156 172 A V E +AG 2 146A 1 -154,-2.1 -154,-2.4 -2,-0.3 2,-0.3 -0.995 15.7 160.0-138.8 141.1 7.1 22.3 32.2 157 173 A R E - G 0 145A 100 -12,-1.9 -12,-3.1 -2,-0.3 2,-0.2 -0.974 48.3 -92.5-153.4 156.5 4.9 24.2 34.7 158 174 A T E - G 0 144A 91 -2,-0.3 2,-0.5 -14,-0.2 -14,-0.3 -0.509 49.7-124.4 -68.9 138.7 1.9 23.4 36.8 159 175 A D - 0 0 44 -16,-3.2 -16,-0.2 -2,-0.2 -1,-0.1 -0.758 30.0-179.9 -92.9 131.5 -1.1 24.4 34.8 160 176 A T + 0 0 140 -2,-0.5 -1,-0.1 3,-0.0 -16,-0.0 0.394 52.2 104.1-108.4 4.0 -3.6 26.9 36.3 161 177 A G S S- 0 0 39 1,-0.2 3,-0.1 3,-0.0 -2,-0.0 0.175 92.1 -37.8 -61.1-166.5 -6.0 27.0 33.3 162 178 A E - 0 0 148 1,-0.1 -1,-0.2 2,-0.1 2,-0.0 -0.404 69.9-111.8 -63.9 129.1 -9.3 25.2 33.3 163 179 A P - 0 0 118 0, 0.0 -1,-0.1 0, 0.0 3,-0.1 -0.338 26.4-162.1 -58.1 135.2 -9.1 21.8 35.2 164 180 A M - 0 0 31 1,-0.1 2,-1.8 3,-0.1 -27,-0.1 0.452 21.4-134.0-107.2 0.8 -9.5 19.0 32.7 165 181 A G S S- 0 0 35 -27,-0.1 2,-0.3 2,-0.1 -1,-0.1 -0.463 73.0 -20.3 87.2 -70.7 -10.4 16.0 34.9 166 182 A R S S+ 0 0 5 -2,-1.8 2,-0.3 -89,-0.1 -28,-0.2 -0.852 100.9 47.5-168.6 136.6 -8.1 13.5 33.3 167 183 A G E S- E 0 137A 0 -30,-2.7 -30,-3.2 -2,-0.3 -85,-0.4 -0.896 70.3 -67.5 133.7-156.1 -6.4 13.2 29.9 168 184 A T E -DE 77 136A 7 -91,-1.3 -91,-2.4 -2,-0.3 2,-0.5 -0.996 19.1-163.7-143.0 136.5 -4.3 15.2 27.4 169 185 A K E -DE 76 135A 40 -34,-3.4 -34,-2.9 -2,-0.3 2,-0.7 -0.989 9.9-163.2-117.8 125.3 -4.7 18.2 25.1 170 186 A V E -DE 75 134A 12 -95,-2.7 -95,-2.5 -2,-0.5 2,-0.6 -0.916 9.1-162.5-105.5 110.7 -2.0 18.6 22.4 171 187 A I E -DE 74 133A 36 -38,-3.4 -38,-2.2 -2,-0.7 2,-0.8 -0.873 2.9-156.2-100.5 118.0 -2.2 22.1 21.1 172 188 A L E -DE 73 132A 0 -99,-2.6 -99,-1.5 -2,-0.6 2,-1.1 -0.860 4.6-155.2 -99.0 111.1 -0.5 22.6 17.7 173 189 A H E -DE 72 131A 44 -42,-2.9 -43,-2.6 -2,-0.8 -42,-1.2 -0.760 32.6-136.3 -82.8 101.9 0.6 26.2 17.1 174 190 A L E - E 0 129A 0 -103,-1.9 -45,-0.3 -2,-1.1 5,-0.1 -0.215 7.2-110.2 -73.2 146.0 0.6 25.9 13.3 175 191 A K > - 0 0 42 -47,-3.0 3,-2.6 1,-0.1 -1,-0.1 -0.426 37.2-108.0 -61.1 144.5 3.2 27.2 11.0 176 192 A E G > S+ 0 0 160 1,-0.3 3,-0.6 2,-0.1 -1,-0.1 0.828 120.1 46.7 -42.5 -42.2 1.9 30.2 8.9 177 193 A D G 3 S+ 0 0 113 1,-0.2 -1,-0.3 2,-0.1 3,-0.2 0.276 101.6 67.9 -89.9 13.8 1.9 28.0 5.7 178 194 A Q G X + 0 0 17 -3,-2.6 3,-1.5 -50,-0.1 -1,-0.2 0.077 57.1 117.0-116.7 23.8 0.1 25.0 7.4 179 195 A T G X + 0 0 62 -3,-0.6 3,-1.9 1,-0.3 4,-0.2 0.580 53.7 86.3 -74.5 -3.9 -3.3 26.6 8.1 180 196 A E G > S+ 0 0 66 1,-0.3 3,-1.9 -3,-0.2 -1,-0.3 0.821 76.7 69.8 -60.4 -28.7 -5.0 24.1 5.8 181 197 A Y G < S+ 0 0 6 -3,-1.5 -1,-0.3 1,-0.3 -2,-0.1 0.368 90.8 61.2 -72.9 3.6 -5.1 21.8 8.9 182 198 A L G < S+ 0 0 4 -3,-1.9 2,-0.3 -116,-0.1 -1,-0.3 0.418 81.9 103.0 -95.8 -8.4 -7.7 24.1 10.3 183 199 A E <> - 0 0 56 -3,-1.9 4,-2.5 -4,-0.2 5,-0.2 -0.653 69.5-140.3 -83.6 136.5 -10.2 23.5 7.5 184 200 A E H > S+ 0 0 84 -2,-0.3 4,-2.4 1,-0.2 5,-0.2 0.902 101.9 50.0 -58.9 -45.7 -13.0 21.2 8.2 185 201 A R H > S+ 0 0 194 1,-0.2 4,-1.9 2,-0.2 -1,-0.2 0.877 110.6 50.1 -65.6 -32.4 -12.9 19.4 4.9 186 202 A R H > S+ 0 0 40 -6,-0.2 4,-2.1 2,-0.2 -2,-0.2 0.937 111.8 47.4 -74.5 -43.9 -9.1 18.8 5.2 187 203 A I H X S+ 0 0 1 -4,-2.5 4,-2.6 -7,-0.2 5,-0.2 0.932 111.7 50.0 -61.1 -42.3 -9.4 17.3 8.7 188 204 A K H X S+ 0 0 118 -4,-2.4 4,-2.7 1,-0.2 5,-0.2 0.916 109.6 52.3 -61.8 -46.4 -12.3 15.0 7.7 189 205 A E H X S+ 0 0 112 -4,-1.9 4,-2.2 -5,-0.2 -1,-0.2 0.927 112.3 44.8 -53.9 -47.9 -10.4 13.8 4.6 190 206 A I H X S+ 0 0 1 -4,-2.1 4,-3.0 2,-0.2 5,-0.5 0.939 113.1 48.9 -68.0 -46.3 -7.3 12.9 6.7 191 207 A V H X S+ 0 0 29 -4,-2.6 4,-2.3 1,-0.2 -2,-0.2 0.939 112.9 48.9 -56.6 -48.7 -9.3 11.2 9.5 192 208 A K H < S+ 0 0 168 -4,-2.7 4,-0.4 -5,-0.2 -1,-0.2 0.902 116.7 42.9 -58.8 -41.5 -11.2 9.2 6.9 193 209 A K H < S+ 0 0 126 -4,-2.2 -2,-0.2 -5,-0.2 -1,-0.2 0.910 132.6 14.2 -70.5 -45.3 -7.9 8.1 5.2 194 210 A H H < S+ 0 0 42 -4,-3.0 -3,-0.2 -5,-0.1 -2,-0.2 0.614 132.4 31.6-113.4 -17.1 -5.7 7.3 8.2 195 211 A S >< + 0 0 7 -4,-2.3 3,-1.2 -5,-0.5 -3,-0.2 0.039 69.3 122.1-135.5 27.3 -7.8 7.0 11.3 196 212 A Q T 3 S+ 0 0 101 -4,-0.4 -4,-0.1 1,-0.3 -1,-0.1 0.660 77.1 51.0 -80.3 -9.6 -11.3 5.6 10.3 197 213 A F T 3 S+ 0 0 182 -3,-0.1 -1,-0.3 2,-0.0 2,-0.1 0.219 71.2 135.2-109.2 14.8 -11.1 2.5 12.5 198 214 A I < - 0 0 46 -3,-1.2 2,-0.4 1,-0.1 4,-0.1 -0.412 55.8-133.9 -61.8 133.4 -10.2 4.1 15.8 199 215 A G S S+ 0 0 61 -2,-0.1 -1,-0.1 2,-0.1 -3,-0.0 -0.007 79.4 69.9 -85.7 36.3 -12.4 2.6 18.6 200 216 A Y S S- 0 0 19 -2,-0.4 -139,-0.2 -138,-0.0 2,-0.1 -0.976 95.1 -91.7-141.8 149.2 -13.4 5.8 20.3 201 217 A P - 0 0 83 0, 0.0 -139,-2.5 0, 0.0 2,-0.6 -0.431 36.9-157.1 -61.8 133.1 -15.7 8.6 19.1 202 218 A I E -c 62 0A 46 -141,-0.2 2,-0.7 -2,-0.1 -139,-0.2 -0.958 6.4-161.9-112.7 116.1 -13.7 11.3 17.3 203 219 A T E -c 63 0A 69 -141,-2.8 -139,-3.1 -2,-0.6 2,-0.9 -0.872 6.3-156.6-105.0 118.4 -15.5 14.6 17.2 204 220 A L E -c 64 0A 38 -2,-0.7 -139,-0.2 -141,-0.2 2,-0.1 -0.774 16.5-150.2 -89.8 105.5 -14.4 17.2 14.7 205 221 A F - 0 0 84 -141,-2.6 2,-0.2 -2,-0.9 -142,-0.0 -0.421 9.1-144.1 -70.1 150.0 -15.5 20.6 16.1 206 222 A V 0 0 94 -141,-0.1 -23,-0.1 -2,-0.1 -1,-0.0 -0.716 360.0 360.0-113.7 167.6 -16.3 23.3 13.6 207 223 A E 0 0 110 -2,-0.2 -140,-0.1 -142,-0.0 -23,-0.0 -0.717 360.0 360.0 -99.0 360.0 -15.7 27.1 13.8