==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=18-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER CHAPERONE 02-MAR-04 1UYF . COMPND 2 MOLECULE: HEAT SHOCK PROTEIN HSP 90-ALPHA; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR L.WRIGHT,X.BARRIL,B.DYMOCK,L.SHERIDAN,A.SURGENOR,M.BESWICK, . 209 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 11027.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 160 76.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 4 1.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 41 19.6 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 18 8.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 33 15.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 57 27.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 5 2.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 1 0 0 0 0 0 1 1 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 0 2 0 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 16 A E 0 0 200 0, 0.0 2,-0.7 0, 0.0 158,-0.3 0.000 360.0 360.0 360.0 134.9 7.6 28.5 38.6 2 17 A V - 0 0 91 156,-0.1 2,-0.4 154,-0.0 156,-0.2 -0.798 360.0-150.7 -77.8 117.4 8.1 27.6 35.0 3 18 A E E -A 157 0A 57 154,-2.6 154,-2.3 -2,-0.7 2,-0.4 -0.811 4.7-152.8 -92.3 133.6 10.8 25.1 34.8 4 19 A T E -A 156 0A 96 -2,-0.4 2,-0.3 152,-0.2 152,-0.2 -0.885 15.5-177.9-107.1 134.6 13.1 24.9 31.7 5 20 A F E -A 155 0A 51 150,-3.1 150,-2.3 -2,-0.4 2,-0.3 -0.945 24.0-124.7-127.9 153.2 14.8 21.7 30.6 6 21 A A E -A 154 0A 80 -2,-0.3 148,-0.2 148,-0.2 2,-0.2 -0.735 26.6-127.9 -89.4 136.7 17.1 20.6 27.8 7 22 A F - 0 0 22 146,-2.1 -1,-0.0 -2,-0.3 148,-0.0 -0.586 38.8 -90.9 -68.0 148.6 16.1 17.7 25.6 8 23 A Q > - 0 0 68 -2,-0.2 4,-2.6 1,-0.1 3,-0.4 -0.283 40.1-111.9 -39.0 143.6 18.5 15.0 25.2 9 24 A A H > S+ 0 0 79 1,-0.2 4,-1.8 2,-0.2 -1,-0.1 0.859 117.6 54.6 -62.8 -32.7 20.8 15.7 22.3 10 25 A E H > S+ 0 0 72 2,-0.2 4,-2.1 1,-0.2 -1,-0.2 0.853 109.7 45.5 -64.8 -42.4 19.3 12.8 20.4 11 26 A I H > S+ 0 0 2 -3,-0.4 4,-2.8 2,-0.2 -2,-0.2 0.904 112.1 52.1 -67.8 -44.1 15.7 14.1 20.8 12 27 A A H X S+ 0 0 25 -4,-2.6 4,-1.9 2,-0.2 -2,-0.2 0.866 109.9 49.5 -57.6 -39.0 16.8 17.6 19.8 13 28 A Q H X S+ 0 0 118 -4,-1.8 4,-2.0 -5,-0.2 -2,-0.2 0.894 110.5 48.9 -69.3 -44.9 18.5 16.1 16.7 14 29 A L H X S+ 0 0 0 -4,-2.1 4,-2.5 1,-0.2 5,-0.2 0.919 109.9 53.5 -58.5 -44.5 15.3 14.2 15.7 15 30 A M H X S+ 0 0 2 -4,-2.8 4,-2.1 1,-0.2 -2,-0.2 0.894 108.9 48.2 -58.7 -40.3 13.4 17.4 16.3 16 31 A S H X S+ 0 0 62 -4,-1.9 4,-2.5 2,-0.2 -1,-0.2 0.861 110.4 51.5 -66.2 -40.8 15.7 19.3 13.9 17 32 A L H X S+ 0 0 50 -4,-2.0 4,-2.9 2,-0.2 -2,-0.2 0.923 109.9 48.4 -59.9 -49.2 15.4 16.6 11.2 18 33 A I H < S+ 0 0 3 -4,-2.5 -2,-0.2 1,-0.2 -1,-0.2 0.940 118.1 42.7 -53.0 -46.3 11.6 16.7 11.4 19 34 A I H < S+ 0 0 67 -4,-2.1 -2,-0.2 -5,-0.2 -1,-0.2 0.858 123.4 35.9 -66.7 -34.9 11.8 20.5 11.1 20 35 A N H < S+ 0 0 119 -4,-2.5 -2,-0.2 -5,-0.1 -3,-0.2 0.756 88.2 99.2-101.4 -33.8 14.5 20.6 8.4 21 36 A T S < S- 0 0 55 -4,-2.9 2,-0.6 -5,-0.2 -4,-0.0 -0.366 75.3-120.2 -56.9 132.7 13.9 17.7 6.0 22 37 A F + 0 0 187 -2,-0.0 2,-0.2 2,-0.0 -1,-0.1 -0.742 54.7 147.3 -68.0 119.0 12.1 18.4 2.8 23 38 A Y - 0 0 37 -2,-0.6 3,-0.1 105,-0.1 -2,-0.0 -0.743 32.1-168.3-164.2 105.5 9.1 16.2 3.0 24 39 A S S S+ 0 0 92 -2,-0.2 2,-2.4 1,-0.2 3,-0.3 0.749 70.3 84.8 -74.6 -25.8 5.7 17.1 1.6 25 40 A N > + 0 0 58 1,-0.2 3,-0.9 2,-0.1 -1,-0.2 -0.306 47.7 143.8 -80.9 59.8 3.5 14.4 3.2 26 41 A K G > + 0 0 38 -2,-2.4 3,-2.0 1,-0.2 -1,-0.2 0.780 46.4 86.2 -74.0 -20.0 3.0 16.4 6.5 27 42 A E G > + 0 0 17 -3,-0.3 3,-1.5 1,-0.3 4,-0.5 0.618 68.4 79.0 -59.3 -19.8 -0.6 15.3 7.0 28 43 A I G <> S+ 0 0 1 -3,-0.9 4,-1.6 1,-0.3 -1,-0.3 0.569 70.0 84.8 -65.1 -15.3 0.4 12.1 8.8 29 44 A F H <> S+ 0 0 0 -3,-2.0 4,-1.7 1,-0.2 -1,-0.3 0.838 86.9 57.6 -49.7 -34.3 1.0 14.2 12.0 30 45 A L H <> S+ 0 0 0 -3,-1.5 4,-2.2 1,-0.2 5,-0.3 0.955 103.1 46.4 -78.4 -39.2 -2.7 13.7 12.6 31 46 A R H > S+ 0 0 65 -4,-0.5 4,-2.8 1,-0.2 -1,-0.2 0.864 109.8 57.4 -65.3 -29.0 -2.9 10.0 12.7 32 47 A E H X S+ 0 0 14 -4,-1.6 4,-1.9 2,-0.2 -1,-0.2 0.897 109.9 41.7 -64.4 -44.0 0.1 9.8 14.9 33 48 A L H X S+ 0 0 4 -4,-1.7 4,-2.0 2,-0.2 -2,-0.2 0.861 116.5 49.1 -74.3 -36.2 -1.5 12.0 17.6 34 49 A I H X S+ 0 0 0 -4,-2.2 4,-3.2 2,-0.2 -2,-0.2 0.891 109.5 51.7 -67.6 -41.2 -4.9 10.3 17.3 35 50 A S H X S+ 0 0 44 -4,-2.8 4,-2.2 -5,-0.3 -2,-0.2 0.927 109.2 50.9 -60.2 -40.0 -3.2 7.0 17.5 36 51 A N H X S+ 0 0 65 -4,-1.9 4,-1.9 2,-0.2 -2,-0.2 0.901 111.1 49.2 -59.9 -41.1 -1.5 8.3 20.8 37 52 A S H X S+ 0 0 3 -4,-2.0 4,-1.8 2,-0.2 -2,-0.2 0.956 110.2 50.4 -60.0 -51.4 -4.9 9.4 22.0 38 53 A S H X S+ 0 0 17 -4,-3.2 4,-2.6 1,-0.2 -2,-0.2 0.890 110.0 49.4 -57.3 -43.2 -6.3 5.9 21.2 39 54 A D H X S+ 0 0 91 -4,-2.2 4,-1.6 1,-0.2 -1,-0.2 0.914 111.5 49.5 -66.9 -41.5 -3.5 4.0 23.1 40 55 A A H X S+ 0 0 20 -4,-1.9 4,-1.6 2,-0.2 41,-1.6 0.795 111.2 49.2 -63.9 -33.1 -4.0 6.3 26.2 41 56 A L H X S+ 0 0 0 -4,-1.8 4,-2.0 39,-0.3 5,-0.2 0.879 108.5 53.4 -74.6 -40.1 -7.8 5.6 26.1 42 57 A D H X S+ 0 0 62 -4,-2.6 4,-2.4 -5,-0.2 -2,-0.2 0.856 108.7 52.1 -55.5 -42.3 -7.0 1.9 25.8 43 58 A K H X S+ 0 0 118 -4,-1.6 4,-2.6 2,-0.2 -2,-0.2 0.900 110.5 44.1 -66.1 -46.9 -4.8 2.2 29.0 44 59 A I H X S+ 0 0 0 -4,-1.6 4,-2.4 2,-0.2 -2,-0.2 0.910 115.2 49.0 -66.8 -38.8 -7.3 3.9 31.2 45 60 A R H < S+ 0 0 118 -4,-2.0 4,-0.5 2,-0.2 -2,-0.2 0.966 113.5 46.8 -65.0 -49.8 -10.1 1.5 30.1 46 61 A Y H >X S+ 0 0 169 -4,-2.4 3,-1.5 -5,-0.2 4,-0.5 0.936 113.1 48.6 -59.3 -46.5 -7.9 -1.5 30.8 47 62 A E H >< S+ 0 0 47 -4,-2.6 3,-0.7 1,-0.3 4,-0.4 0.843 104.4 60.9 -62.2 -33.5 -6.8 -0.1 34.2 48 63 A S T 3< S+ 0 0 14 -4,-2.4 -1,-0.3 1,-0.2 -2,-0.2 0.531 88.9 72.7 -73.0 1.6 -10.4 0.6 35.2 49 64 A L T <4 S+ 0 0 130 -3,-1.5 -1,-0.2 -4,-0.5 -2,-0.2 0.800 109.8 29.1 -84.4 -34.5 -11.4 -3.1 34.9 50 65 A T S << S+ 0 0 129 -3,-0.7 -1,-0.2 -4,-0.5 -2,-0.2 0.295 134.9 34.2-101.0 6.5 -9.5 -4.0 38.0 51 66 A D > - 0 0 60 -4,-0.4 3,-2.0 1,-0.1 4,-0.2 -0.431 61.9-177.1-157.6 81.2 -10.0 -0.6 39.6 52 67 A P G > S+ 0 0 81 0, 0.0 3,-1.5 0, 0.0 -4,-0.1 0.690 77.5 71.7 -53.5 -28.0 -13.3 1.1 38.8 53 68 A S G > S+ 0 0 59 1,-0.3 3,-2.8 2,-0.2 4,-0.3 0.713 77.8 80.4 -61.9 -24.4 -12.5 4.3 40.8 54 69 A K G < S+ 0 0 52 -3,-2.0 3,-0.3 1,-0.3 -1,-0.3 0.683 91.4 54.0 -55.2 -22.8 -9.9 5.3 38.0 55 70 A L G X S+ 0 0 18 -3,-1.5 3,-1.9 -4,-0.2 -1,-0.3 0.342 75.5 97.0 -93.5 8.3 -12.8 6.5 36.1 56 71 A D T < S+ 0 0 130 -3,-2.8 -1,-0.2 1,-0.3 -2,-0.1 0.671 79.4 63.2 -66.9 -15.3 -14.2 8.9 38.9 57 72 A S T 3 S- 0 0 36 -3,-0.3 -1,-0.3 -4,-0.3 -2,-0.1 0.332 131.7 -36.5 -90.3 7.9 -12.4 11.6 37.0 58 73 A G < - 0 0 24 -3,-1.9 -1,-0.3 108,-0.1 -2,-0.1 -0.015 44.0-149.6 141.9 127.1 -14.7 11.0 34.0 59 74 A K + 0 0 130 -3,-0.1 2,-0.2 -2,-0.1 -3,-0.1 0.767 68.2 96.9 -84.4 -29.2 -16.3 8.0 32.4 60 75 A E - 0 0 136 -5,-0.1 2,-0.6 1,-0.1 0, 0.0 -0.474 56.1-159.4 -75.3 129.6 -16.5 9.2 28.8 61 76 A L + 0 0 31 -2,-0.2 2,-0.3 17,-0.1 19,-0.1 -0.926 37.7 125.1-113.8 104.5 -13.7 7.9 26.5 62 77 A H - 0 0 52 -2,-0.6 17,-1.5 139,-0.1 2,-0.4 -0.934 50.0-125.7-161.0 170.7 -13.3 10.1 23.5 63 78 A I E -Bc 78 203A 0 139,-2.0 141,-2.4 -2,-0.3 2,-0.4 -1.000 19.4-166.7-131.9 126.4 -11.3 12.3 21.2 64 79 A N E -Bc 77 204A 25 13,-2.4 13,-2.6 -2,-0.4 2,-0.5 -0.952 7.2-158.3-114.7 134.6 -12.1 15.9 20.1 65 80 A L E -Bc 76 205A 0 139,-3.1 141,-2.3 -2,-0.4 11,-0.2 -0.954 15.4-174.7-108.5 122.4 -10.4 17.8 17.3 66 81 A I E -B 75 0A 50 9,-3.0 9,-2.2 -2,-0.5 2,-0.2 -0.918 7.3-164.8-126.1 107.4 -10.8 21.5 17.7 67 82 A P E -B 74 0A 8 0, 0.0 2,-0.3 0, 0.0 7,-0.2 -0.620 4.5-175.0 -82.6 146.7 -9.6 24.0 15.1 68 83 A N E >> -B 73 0A 50 5,-2.1 5,-2.0 -2,-0.2 4,-1.0 -0.790 9.0-175.1-144.2 98.3 -9.3 27.7 16.0 69 84 A K T 45S+ 0 0 112 -2,-0.3 -1,-0.1 3,-0.2 5,-0.0 0.774 84.3 57.7 -61.8 -31.2 -8.4 30.1 13.1 70 85 A Q T 45S+ 0 0 178 1,-0.2 -1,-0.2 3,-0.1 -2,-0.0 0.924 119.2 29.0 -68.1 -47.6 -8.1 33.1 15.4 71 86 A D T 45S- 0 0 106 2,-0.1 -1,-0.2 -3,-0.1 -2,-0.2 0.572 106.0-129.7 -81.3 -15.8 -5.4 31.5 17.6 72 87 A R T <5 + 0 0 76 -4,-1.0 103,-1.6 1,-0.2 2,-0.3 0.942 60.1 138.5 58.9 52.1 -4.2 29.5 14.6 73 88 A T E < -BD 68 174A 10 -5,-2.0 -5,-2.1 101,-0.2 2,-0.4 -0.943 45.3-160.9-124.4 146.0 -4.3 26.2 16.7 74 89 A L E -BD 67 173A 0 99,-1.9 99,-2.6 -2,-0.3 2,-0.4 -0.998 22.2-163.4-116.5 126.9 -5.5 22.7 16.1 75 90 A T E -BD 66 172A 12 -9,-2.2 -9,-3.0 -2,-0.4 2,-0.5 -0.926 11.9-160.2-119.4 131.9 -6.1 20.9 19.4 76 91 A I E -BD 65 171A 2 95,-2.2 95,-2.7 -2,-0.4 2,-0.4 -0.976 18.3-173.0-110.6 112.0 -6.3 17.2 19.8 77 92 A V E +BD 64 170A 22 -13,-2.6 -13,-2.4 -2,-0.5 2,-0.3 -0.902 7.9 172.0-112.4 130.5 -8.1 16.4 23.1 78 93 A D E -BD 63 169A 9 91,-2.6 91,-1.1 -2,-0.4 -15,-0.2 -0.914 34.7-141.4-130.2 162.5 -8.6 12.9 24.7 79 94 A T + 0 0 24 -17,-1.5 89,-0.2 -2,-0.3 -16,-0.1 -0.196 60.6 132.2-107.8 38.6 -9.9 11.6 28.0 80 95 A G S S- 0 0 0 89,-0.1 -39,-0.3 -18,-0.1 -40,-0.1 0.151 78.1 -67.5 -70.0-160.9 -7.2 8.9 28.2 81 96 A I - 0 0 13 -41,-1.6 59,-0.6 1,-0.1 87,-0.2 0.706 69.3-145.6 -71.6 -23.8 -5.0 8.1 31.1 82 97 A G - 0 0 5 57,-0.2 2,-0.4 85,-0.2 57,-0.2 -0.038 15.3 -85.4 79.3 174.0 -2.9 11.3 31.1 83 98 A M - 0 0 41 85,-0.4 56,-0.4 62,-0.1 62,-0.2 -0.971 27.0-137.5-124.6 139.2 0.6 11.9 31.9 84 99 A T >> - 0 0 24 -2,-0.4 4,-1.8 54,-0.1 3,-0.6 -0.404 35.4-104.6 -81.3 162.2 2.4 12.5 35.2 85 100 A K H 3> S+ 0 0 59 1,-0.2 4,-2.2 2,-0.2 5,-0.3 0.894 123.2 58.3 -53.5 -39.4 5.1 15.1 35.6 86 101 A A H 3>>S+ 0 0 44 1,-0.2 5,-2.6 2,-0.2 4,-2.4 0.870 104.8 51.6 -59.2 -36.2 7.7 12.2 35.7 87 102 A D H <4>S+ 0 0 32 -3,-0.6 5,-2.0 3,-0.2 6,-0.4 0.947 111.6 46.9 -56.9 -53.8 6.4 11.2 32.2 88 103 A L H <5S+ 0 0 17 -4,-1.8 -2,-0.2 1,-0.2 -1,-0.2 0.814 124.1 29.7 -61.1 -43.4 6.9 14.7 30.9 89 104 A I H <5S- 0 0 38 -4,-2.2 -2,-0.2 -5,-0.2 -3,-0.2 0.866 137.2 -5.4 -87.8 -46.2 10.3 15.3 32.2 90 105 A N T X5S+ 0 0 100 -4,-2.4 4,-1.8 -5,-0.3 -3,-0.2 0.767 114.2 57.6-118.5 -51.2 12.0 11.8 32.3 91 106 A N H > S+ 0 0 19 -6,-0.4 4,-1.3 2,-0.2 -1,-0.2 0.823 104.5 57.1 -70.7 -32.0 12.5 10.7 26.9 94 109 A T H >X S+ 0 0 101 -4,-1.8 4,-0.7 2,-0.2 3,-0.5 0.954 114.2 39.3 -65.1 -45.6 14.3 7.6 28.1 95 110 A I H >X S+ 0 0 106 -4,-1.6 4,-1.3 1,-0.2 3,-0.6 0.911 111.2 58.3 -70.9 -45.8 12.1 5.5 25.9 96 111 A A H 3X S+ 0 0 10 -4,-2.6 4,-2.2 1,-0.2 -1,-0.2 0.737 94.0 68.4 -51.4 -29.6 12.2 8.0 23.0 97 112 A K H < S+ 0 0 102 -4,-2.3 3,-1.0 1,-0.2 -1,-0.2 0.901 109.8 54.9 -66.9 -39.5 18.9 4.3 11.1 106 121 A A H 3<>S+ 0 0 21 -4,-2.1 5,-2.4 1,-0.3 4,-0.3 0.856 98.5 58.9 -65.5 -37.3 15.7 3.3 9.2 107 122 A L H 3<5S+ 0 0 41 -4,-2.3 2,-0.8 1,-0.2 3,-0.4 0.771 104.1 58.9 -60.4 -22.8 15.7 6.6 7.3 108 123 A Q T <<5S+ 0 0 161 -3,-1.0 -1,-0.2 -4,-0.7 4,-0.1 -0.859 101.5 47.2-111.4 94.4 19.1 5.4 6.2 109 124 A A T 5S- 0 0 99 -2,-0.8 -1,-0.2 2,-0.1 -2,-0.2 -0.096 137.0 -82.9 142.9 -22.8 18.1 2.2 4.6 110 125 A G T 5S+ 0 0 67 -3,-0.4 -3,-0.2 -4,-0.3 -2,-0.1 0.667 79.9 141.8 105.8 20.6 15.4 4.2 2.8 111 126 A A < - 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