==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=18-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER CHAPERONE 02-MAR-04 1UYK . COMPND 2 MOLECULE: HEAT SHOCK PROTEIN HSP 90-ALPHA; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR L.WRIGHT,X.BARRIL,B.DYMOCK,L.SHERIDAN,A.SURGENOR,M.BESWICK, . 208 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 10807.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 160 76.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 4 1.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 41 19.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 17 8.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 33 15.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 58 27.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 6 2.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 1 0 0 0 0 0 1 1 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 0 2 0 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 16 A E 0 0 201 0, 0.0 158,-0.4 0, 0.0 2,-0.3 0.000 360.0 360.0 360.0 121.7 7.1 29.4 38.3 2 17 A V - 0 0 71 156,-0.1 2,-0.4 154,-0.0 156,-0.2 -0.608 360.0-150.9 -80.4 130.8 8.2 27.8 34.9 3 18 A E E -A 157 0A 65 154,-2.2 154,-2.2 -2,-0.3 2,-0.5 -0.921 7.8-149.3-102.1 140.5 11.0 25.2 34.8 4 19 A T E -A 156 0A 101 -2,-0.4 2,-0.4 152,-0.2 152,-0.2 -0.934 15.9-177.5-116.0 129.0 13.3 24.8 31.8 5 20 A F E -A 155 0A 47 150,-2.4 150,-2.0 -2,-0.5 2,-0.3 -0.886 23.6-128.8-123.7 148.8 14.7 21.6 30.8 6 21 A A E -A 154 0A 83 -2,-0.4 148,-0.3 148,-0.2 2,-0.2 -0.771 28.5-121.7 -89.6 142.9 17.0 20.6 28.0 7 22 A F - 0 0 22 146,-2.3 82,-0.0 -2,-0.3 -1,-0.0 -0.570 38.9 -93.5 -68.9 146.3 16.0 17.6 25.7 8 23 A Q >> - 0 0 77 -2,-0.2 4,-1.6 1,-0.1 3,-0.6 -0.295 44.1-110.0 -44.2 148.0 18.3 14.6 25.6 9 24 A A H 3> S+ 0 0 70 1,-0.2 4,-2.4 2,-0.2 5,-0.2 0.894 117.9 55.2 -57.5 -45.9 20.7 15.1 22.6 10 25 A E H 3> S+ 0 0 68 2,-0.2 4,-1.8 3,-0.2 -1,-0.2 0.827 109.7 47.5 -47.3 -42.7 19.2 12.3 20.5 11 26 A I H <> S+ 0 0 2 -3,-0.6 4,-3.6 2,-0.2 3,-0.5 0.982 111.7 49.0 -65.0 -62.5 15.6 13.9 20.9 12 27 A A H X S+ 0 0 21 -4,-1.6 4,-1.4 1,-0.3 -2,-0.2 0.807 111.9 51.2 -47.3 -41.1 16.9 17.4 20.0 13 28 A Q H X S+ 0 0 113 -4,-2.4 4,-2.2 -5,-0.2 -1,-0.3 0.903 111.3 46.2 -66.0 -40.5 18.5 15.8 17.0 14 29 A L H X S+ 0 0 0 -4,-1.8 4,-2.1 -3,-0.5 5,-0.3 0.958 110.1 53.0 -71.7 -43.0 15.3 14.0 15.9 15 30 A M H X S+ 0 0 1 -4,-3.6 4,-2.1 1,-0.2 -1,-0.2 0.884 111.0 48.8 -54.3 -38.0 13.2 17.2 16.4 16 31 A S H X S+ 0 0 58 -4,-1.4 4,-2.0 -5,-0.3 5,-0.2 0.912 110.1 51.2 -67.2 -40.4 15.8 19.0 14.1 17 32 A L H X S+ 0 0 46 -4,-2.2 4,-3.3 2,-0.2 3,-0.3 0.963 111.3 45.2 -60.4 -59.3 15.6 16.3 11.5 18 33 A I H < S+ 0 0 2 -4,-2.1 -1,-0.2 1,-0.2 -2,-0.2 0.833 116.8 47.3 -46.9 -46.6 11.7 16.4 11.3 19 34 A I H < S+ 0 0 68 -4,-2.1 -1,-0.2 -5,-0.3 -2,-0.2 0.733 122.0 35.0 -71.6 -24.7 11.9 20.3 11.1 20 35 A N H < S+ 0 0 124 -4,-2.0 -2,-0.2 -3,-0.3 -3,-0.2 0.881 90.1 94.5 -98.2 -43.0 14.7 20.3 8.4 21 36 A T S < S- 0 0 57 -4,-3.3 2,-0.7 -5,-0.2 -4,-0.0 -0.229 76.3-121.7 -50.1 134.4 14.1 17.4 6.1 22 37 A F + 0 0 185 2,-0.0 2,-0.3 0, 0.0 -1,-0.1 -0.686 52.4 144.4 -78.4 117.5 12.2 18.2 3.0 23 38 A Y - 0 0 38 -2,-0.7 89,-0.0 1,-0.1 -2,-0.0 -0.840 34.9-161.9-161.0 125.7 9.2 15.9 2.9 24 39 A S S S+ 0 0 90 -2,-0.3 2,-4.2 1,-0.1 3,-0.3 0.828 71.7 88.2 -76.7 -44.5 5.7 16.9 1.7 25 40 A N > + 0 0 58 1,-0.2 3,-0.7 2,-0.1 -1,-0.1 -0.137 47.1 144.0 -56.2 60.5 3.5 14.2 3.3 26 41 A K T > + 0 0 39 -2,-4.2 3,-2.1 1,-0.2 -1,-0.2 0.876 47.5 83.2 -73.4 -36.5 3.1 16.3 6.5 27 42 A E T >> S+ 0 0 16 -3,-0.3 3,-1.3 1,-0.3 4,-0.6 0.648 70.4 79.1 -39.9 -23.9 -0.6 15.2 7.1 28 43 A I H <> + 0 0 1 -3,-0.7 4,-0.7 1,-0.2 -1,-0.3 0.669 69.4 86.3 -66.4 -5.8 0.5 11.9 8.9 29 44 A F H X> S+ 0 0 0 -3,-2.1 4,-1.5 1,-0.2 3,-0.7 0.905 86.8 53.9 -61.5 -29.5 1.2 14.0 12.0 30 45 A L H <> S+ 0 0 0 -3,-1.3 4,-2.5 1,-0.3 5,-0.3 0.915 102.4 51.3 -73.2 -47.1 -2.6 13.5 12.9 31 46 A R H 3X S+ 0 0 55 -4,-0.6 4,-0.6 1,-0.2 -1,-0.3 0.581 108.8 55.0 -71.6 -3.9 -2.8 9.8 12.8 32 47 A E H X S+ 0 0 166 -4,-1.3 3,-1.4 1,-0.2 4,-0.6 0.937 110.9 53.3 -56.0 -49.6 -7.8 -1.5 31.2 47 62 A E H >< S+ 0 0 43 -4,-3.2 3,-0.8 1,-0.3 4,-0.4 0.864 106.0 57.7 -58.7 -28.5 -6.6 -0.1 34.5 48 63 A S H 3< S+ 0 0 15 -4,-1.4 -1,-0.3 -3,-0.4 -2,-0.2 0.650 87.6 73.4 -80.2 -16.8 -10.3 0.5 35.4 49 64 A L H << S+ 0 0 137 -3,-1.4 -1,-0.2 -4,-0.7 -2,-0.2 0.779 109.3 31.7 -68.0 -29.5 -11.3 -3.1 35.0 50 65 A T S << S+ 0 0 123 -3,-0.8 -1,-0.2 -4,-0.6 -2,-0.2 0.391 131.8 32.9-106.1 -1.8 -9.6 -4.0 38.3 51 66 A D > - 0 0 65 -4,-0.4 3,-1.4 -3,-0.1 -1,-0.3 -0.667 61.9-173.6-157.4 87.3 -10.1 -0.6 40.1 52 67 A P G > S+ 0 0 97 0, 0.0 3,-1.2 0, 0.0 -4,-0.1 0.659 79.5 73.4 -54.5 -25.6 -13.4 1.2 39.2 53 68 A S G > S+ 0 0 65 1,-0.2 3,-2.1 2,-0.1 4,-0.4 0.698 77.5 83.5 -63.9 -19.5 -12.5 4.4 41.2 54 69 A K G < S+ 0 0 49 -3,-1.4 3,-0.4 1,-0.3 -1,-0.2 0.775 89.2 49.9 -49.8 -31.4 -10.0 5.1 38.2 55 70 A L G X S+ 0 0 28 -3,-1.2 3,-1.3 1,-0.2 -1,-0.3 0.130 77.4 100.0-103.7 13.8 -12.8 6.6 36.2 56 71 A D T < S+ 0 0 124 -3,-2.1 -1,-0.2 1,-0.2 3,-0.2 0.901 79.0 59.0 -57.8 -47.2 -14.0 8.9 39.0 57 72 A S T 3 S- 0 0 36 -4,-0.4 -1,-0.2 -3,-0.4 -2,-0.1 0.471 135.4 -37.4 -57.6 -0.1 -12.0 11.7 37.2 58 73 A G < - 0 0 17 -3,-1.3 -1,-0.2 108,-0.1 -2,-0.1 0.047 41.3-150.2 140.7 119.0 -14.4 10.9 34.2 59 74 A K + 0 0 142 -3,-0.2 2,-0.3 2,-0.0 -3,-0.1 0.735 66.7 101.5 -79.0 -25.1 -16.1 8.0 32.6 60 75 A E - 0 0 121 -5,-0.1 2,-0.8 1,-0.1 19,-0.0 -0.450 53.8-160.8 -70.3 123.2 -16.3 9.2 28.9 61 76 A L + 0 0 36 -2,-0.3 2,-0.3 17,-0.1 -1,-0.1 -0.787 39.6 121.1-104.6 96.3 -13.6 7.6 26.6 62 77 A H - 0 0 37 -2,-0.8 17,-1.7 139,-0.2 2,-0.3 -0.895 52.8-130.3-144.8 165.2 -13.3 9.8 23.5 63 78 A I E -Bc 78 203A 0 139,-3.0 141,-2.4 -2,-0.3 2,-0.4 -0.967 20.4-164.0-114.5 141.4 -11.0 12.0 21.2 64 79 A N E -Bc 77 204A 25 13,-2.6 13,-2.1 -2,-0.3 2,-0.5 -0.979 8.3-154.8-118.7 133.8 -12.0 15.7 20.1 65 80 A L E -Bc 76 205A 0 139,-2.6 141,-2.8 -2,-0.4 11,-0.2 -0.990 17.8-173.0-103.3 128.2 -10.3 17.4 17.3 66 81 A I E -B 75 0A 48 9,-2.0 9,-2.3 -2,-0.5 2,-0.4 -0.926 5.5-170.3-127.2 104.0 -10.7 21.2 17.8 67 82 A P E -B 74 0A 9 0, 0.0 2,-0.4 0, 0.0 7,-0.2 -0.795 4.1-177.5 -98.3 136.0 -9.6 23.8 15.2 68 83 A N E >> -B 73 0A 39 5,-2.6 5,-1.8 -2,-0.4 4,-0.8 -0.944 9.4-172.4-134.4 112.0 -9.5 27.5 16.0 69 84 A K T 45S+ 0 0 120 -2,-0.4 -1,-0.1 1,-0.2 5,-0.0 0.716 87.3 57.1 -84.6 -24.4 -8.5 29.8 13.1 70 85 A Q T 45S+ 0 0 157 1,-0.2 -1,-0.2 3,-0.1 -2,-0.0 0.909 116.3 36.4 -66.1 -40.6 -8.4 32.9 15.3 71 86 A D T 45S- 0 0 108 2,-0.1 -2,-0.2 1,-0.0 -1,-0.2 0.666 104.4-130.7 -84.3 -4.3 -5.8 31.1 17.6 72 87 A R T <5 + 0 0 74 -4,-0.8 103,-1.8 1,-0.2 2,-0.3 0.794 63.4 134.2 42.6 47.9 -4.1 29.4 14.7 73 88 A T E < -BD 68 174A 13 -5,-1.8 -5,-2.6 101,-0.2 2,-0.4 -0.936 48.8-162.7-126.7 140.6 -4.4 26.1 16.7 74 89 A L E -BD 67 173A 0 99,-1.7 99,-2.8 -2,-0.3 2,-0.5 -0.985 22.4-162.1-103.0 123.1 -5.4 22.5 16.2 75 90 A T E -BD 66 172A 18 -9,-2.3 -9,-2.0 -2,-0.4 2,-0.8 -0.895 12.1-160.3-115.5 126.0 -6.1 20.7 19.5 76 91 A I E -BD 65 171A 0 95,-1.4 95,-1.9 -2,-0.5 2,-0.5 -0.889 20.0-171.3-104.6 99.9 -6.2 17.0 20.0 77 92 A V E +BD 64 170A 17 -13,-2.1 -13,-2.6 -2,-0.8 2,-0.3 -0.774 8.4 172.5 -96.8 130.0 -8.1 16.4 23.2 78 93 A D E -BD 63 169A 6 91,-2.5 91,-1.2 -2,-0.5 -15,-0.2 -0.980 33.7-146.3-133.6 149.8 -8.4 13.0 24.8 79 94 A T + 0 0 24 -17,-1.7 89,-0.2 -2,-0.3 -16,-0.1 -0.165 60.0 126.3-101.0 39.8 -9.8 11.6 28.1 80 95 A G S S- 0 0 0 89,-0.1 -39,-0.3 -18,-0.1 -40,-0.1 0.111 82.0 -65.1 -74.3-164.0 -7.1 8.8 28.5 81 96 A I S S- 0 0 15 -41,-1.9 59,-0.4 1,-0.1 87,-0.2 0.739 71.1-151.2 -63.0 -22.2 -4.7 8.0 31.3 82 97 A G - 0 0 6 85,-0.2 2,-0.4 57,-0.1 57,-0.2 -0.099 17.9 -77.5 69.3-172.4 -2.8 11.3 31.0 83 98 A M - 0 0 37 85,-0.4 56,-0.4 62,-0.1 62,-0.1 -0.961 29.4-139.3-130.5 133.9 0.8 12.0 31.9 84 99 A T > - 0 0 28 -2,-0.4 4,-2.3 54,-0.1 5,-0.1 -0.281 33.6-107.4 -78.8 176.0 2.7 12.5 35.3 85 100 A K H > S+ 0 0 61 2,-0.2 4,-2.8 1,-0.2 5,-0.5 0.937 123.6 57.0 -72.6 -41.0 5.5 15.1 35.8 86 101 A A H >>S+ 0 0 46 1,-0.2 4,-2.3 2,-0.2 5,-2.2 0.891 105.7 48.8 -53.6 -47.2 7.9 12.2 35.9 87 102 A D H 4>S+ 0 0 37 3,-0.2 5,-2.7 4,-0.2 6,-0.4 0.939 114.3 46.7 -50.5 -55.9 6.7 11.2 32.5 88 103 A L H <5S+ 0 0 13 -4,-2.3 -2,-0.2 1,-0.2 -1,-0.2 0.890 124.8 27.5 -55.0 -50.1 7.1 14.8 31.2 89 104 A I H <5S+ 0 0 40 -4,-2.8 -3,-0.2 -5,-0.1 -2,-0.2 0.896 138.1 3.7 -79.3 -46.7 10.6 15.5 32.6 90 105 A N T >X5S+ 0 0 93 -4,-2.3 4,-1.8 -5,-0.5 3,-0.7 0.881 116.3 49.3-118.2 -59.8 12.1 12.0 32.8 91 106 A N H 3> S+ 0 0 16 -3,-0.7 4,-1.0 -6,-0.4 -2,-0.2 0.842 109.8 51.0 -75.6 -42.7 12.9 11.0 27.3 94 109 A T H < S+ 0 0 73 -4,-1.8 4,-0.5 2,-0.2 3,-0.3 0.913 114.2 42.8 -67.4 -38.0 14.1 7.7 28.6 95 110 A I H >X S+ 0 0 121 -4,-1.6 4,-1.1 1,-0.2 3,-0.5 0.909 111.2 55.3 -77.4 -36.8 11.7 5.7 26.4 96 111 A A H 3X S+ 0 0 7 -4,-2.1 4,-2.2 1,-0.2 -1,-0.2 0.651 88.2 77.1 -67.0 -24.7 12.3 7.8 23.3 97 112 A K H 3X S+ 0 0 90 -4,-1.0 4,-1.2 -3,-0.3 -1,-0.2 0.894 101.0 40.1 -61.6 -47.2 16.1 7.4 23.2 98 113 A S H <> S+ 0 0 88 -3,-0.5 4,-2.2 -4,-0.5 3,-0.4 0.956 112.5 57.0 -58.7 -58.8 16.0 3.9 21.9 99 114 A G H X S+ 0 0 10 -4,-1.1 4,-1.7 1,-0.2 -2,-0.2 0.843 108.5 49.0 -27.6 -50.4 13.0 4.9 19.5 100 115 A T H X S+ 0 0 2 -4,-2.2 4,-2.2 2,-0.2 5,-0.2 0.820 108.0 49.7 -77.2 -33.7 15.2 7.7 18.0 101 116 A K H X S+ 0 0 137 -4,-1.2 4,-3.3 -3,-0.4 5,-0.3 0.977 113.3 47.7 -66.0 -50.4 18.3 5.7 17.3 102 117 A A H X S+ 0 0 38 -4,-2.2 4,-2.1 2,-0.2 -2,-0.2 0.882 113.8 45.9 -54.1 -45.3 16.3 3.0 15.6 103 118 A F H X S+ 0 0 1 -4,-1.7 4,-1.8 -5,-0.2 -1,-0.2 0.964 114.5 48.7 -61.7 -53.1 14.3 5.6 13.4 104 119 A M H >X S+ 0 0 44 -4,-2.2 4,-1.0 1,-0.3 3,-0.7 0.946 111.5 49.2 -55.6 -57.1 17.4 7.5 12.5 105 120 A E H 3< S+ 0 0 119 -4,-3.3 -1,-0.3 -5,-0.2 -2,-0.2 0.833 110.6 51.2 -47.3 -39.6 19.2 4.2 11.6 106 121 A A H 3<>S+ 0 0 26 -4,-2.1 5,-1.3 -5,-0.3 -1,-0.2 0.821 96.7 70.2 -71.2 -27.6 16.2 3.2 9.4 107 122 A L H X<5S+ 0 0 41 -4,-1.8 3,-0.7 -3,-0.7 2,-0.5 0.792 96.4 50.3 -64.3 -43.3 16.1 6.5 7.5 108 123 A Q T 3<5S+ 0 0 155 -4,-1.0 4,-0.0 1,-0.2 0, 0.0 -0.896 100.9 58.5 -85.9 131.7 19.4 5.9 5.5 109 124 A A T 3 5S- 0 0 104 -2,-0.5 -1,-0.2 2,-0.1 -2,-0.1 0.140 133.9 -95.3 108.5 -5.2 18.6 2.4 4.2 110 125 A G T < 5S+ 0 0 68 -3,-0.7 -3,-0.2 1,-0.2 2,-0.2 0.773 77.8 140.9 65.8 37.6 15.7 4.5 2.8 111 126 A A < - 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