==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=26-AUG-2012 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 13-DEC-11 3V35 . COMPND 2 MOLECULE: ALDOSE REDUCTASE; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR X.ZHENG,L.ZHANG,Y.CHEN,H.LUO,X.HU . 316 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13672.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 203 64.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 34 10.8 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 10 3.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 15 4.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 40 12.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 85 26.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 8 2.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 3 1 2 0 0 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 3 3 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 0 A M 0 0 103 0, 0.0 2,-0.2 0, 0.0 254,-0.1 0.000 360.0 360.0 360.0 121.9 16.8 -13.8 20.2 2 1 A A - 0 0 70 1,-0.1 3,-0.0 2,-0.1 13,-0.0 -0.560 360.0-137.9 -86.3 157.8 16.5 -13.1 16.5 3 2 A S S S+ 0 0 75 -2,-0.2 12,-2.8 1,-0.1 13,-0.4 0.578 81.3 41.4 -95.7 -10.6 16.1 -9.5 15.3 4 3 A R E -A 14 0A 114 10,-0.3 2,-0.4 11,-0.1 -1,-0.1 -0.986 67.9-141.7-137.6 146.1 13.5 -10.1 12.6 5 4 A L E -A 13 0A 28 8,-2.8 8,-3.1 -2,-0.3 2,-0.4 -0.895 24.5-119.2-106.3 139.8 10.4 -12.2 12.2 6 5 A L E -A 12 0A 110 -2,-0.4 6,-0.2 6,-0.2 2,-0.2 -0.624 28.8-151.7 -76.8 125.4 9.4 -14.0 9.0 7 6 A L > - 0 0 5 4,-3.2 3,-1.9 -2,-0.4 198,-0.1 -0.518 28.4-107.0 -90.4 164.9 6.0 -12.9 7.6 8 7 A N T 3 S+ 0 0 72 196,-0.4 171,-0.1 1,-0.3 -1,-0.1 0.354 117.7 63.7 -77.6 7.0 3.7 -15.0 5.5 9 8 A N T 3 S- 0 0 60 2,-0.2 -1,-0.3 172,-0.1 3,-0.1 0.354 120.5-106.8-101.4 -0.4 4.6 -13.0 2.4 10 9 A G S < S+ 0 0 61 -3,-1.9 2,-0.2 1,-0.3 -2,-0.1 0.430 82.6 120.5 91.5 0.4 8.2 -14.2 2.7 11 10 A A - 0 0 13 144,-0.1 -4,-3.2 95,-0.1 2,-0.5 -0.583 61.0-124.0 -95.0 159.7 9.6 -10.9 4.0 12 11 A K E -A 6 0A 111 -6,-0.2 -6,-0.2 -2,-0.2 -1,-0.0 -0.910 19.1-155.1-109.2 130.8 11.4 -10.3 7.3 13 12 A M E -A 5 0A 1 -8,-3.1 -8,-2.8 -2,-0.5 29,-0.1 -0.895 21.5-119.1-110.2 122.5 10.0 -7.7 9.7 14 13 A P E -A 4 0A 17 0, 0.0 -10,-0.3 0, 0.0 246,-0.1 -0.380 18.3-138.8 -58.6 134.5 12.4 -6.1 12.3 15 14 A I S S+ 0 0 4 -12,-2.8 245,-3.0 244,-0.1 2,-0.5 0.661 87.6 56.4 -75.6 -14.9 11.0 -6.9 15.8 16 15 A L B +b 260 0B 5 -13,-0.4 25,-0.6 243,-0.2 2,-0.3 -0.967 67.0 166.0-118.3 131.4 11.7 -3.4 17.0 17 16 A G - 0 0 0 243,-2.2 2,-0.5 -2,-0.5 26,-0.2 -0.907 36.4-108.1-136.0 166.1 10.3 -0.3 15.3 18 17 A L E -c 43 0B 2 24,-2.2 26,-3.0 -2,-0.3 245,-0.2 -0.858 29.1-142.6 -97.2 124.3 9.8 3.4 16.1 19 18 A G E -cd 44 263B 4 243,-2.0 245,-0.7 -2,-0.5 26,-0.1 -0.516 14.8-173.9 -80.0 153.0 6.3 4.6 16.8 20 19 A T > + 0 0 0 24,-0.6 3,-1.6 -2,-0.2 2,-0.4 0.314 37.7 124.7-132.3 6.7 5.2 8.0 15.5 21 20 A W T 3 S+ 0 0 64 1,-0.2 28,-0.1 23,-0.1 -2,-0.1 -0.613 88.6 12.6 -70.0 127.9 1.8 8.7 17.0 22 21 A K T 3 S+ 0 0 52 -2,-0.4 -1,-0.2 1,-0.3 28,-0.0 0.419 90.9 134.7 80.3 4.2 2.0 12.1 18.8 23 22 A S < - 0 0 5 -3,-1.6 -1,-0.3 241,-0.1 5,-0.1 -0.758 57.5-128.3 -83.0 111.2 5.4 12.9 17.3 24 23 A P >> - 0 0 55 0, 0.0 4,-2.5 0, 0.0 3,-2.3 -0.243 13.9-117.9 -62.9 148.0 5.0 16.6 16.2 25 24 A P H 3> S+ 0 0 61 0, 0.0 4,-0.7 0, 0.0 26,-0.0 0.836 115.5 55.4 -51.6 -37.5 5.9 17.4 12.5 26 25 A G H 34 S+ 0 0 76 1,-0.2 4,-0.1 2,-0.1 25,-0.0 0.491 119.9 29.5 -77.6 -4.5 8.7 19.7 13.8 27 26 A Q H <> S+ 0 0 92 -3,-2.3 4,-2.0 2,-0.1 -1,-0.2 0.551 101.0 75.2-124.6 -20.9 10.3 16.9 15.8 28 27 A V H X S+ 0 0 0 -4,-2.5 4,-2.6 2,-0.2 5,-0.2 0.813 90.6 59.4 -71.2 -26.9 9.5 13.6 14.0 29 28 A T H X S+ 0 0 25 -4,-0.7 4,-2.1 -5,-0.2 -1,-0.2 0.965 110.6 41.4 -64.2 -50.5 12.1 14.2 11.3 30 29 A E H > S+ 0 0 102 1,-0.2 4,-2.5 2,-0.2 5,-0.2 0.894 113.7 55.7 -60.8 -38.6 14.9 14.4 13.8 31 30 A A H X S+ 0 0 2 -4,-2.0 4,-2.3 1,-0.2 -2,-0.2 0.922 109.8 43.4 -63.2 -44.9 13.4 11.5 15.7 32 31 A V H X S+ 0 0 0 -4,-2.6 4,-2.5 2,-0.2 -1,-0.2 0.874 112.4 53.9 -69.2 -37.1 13.4 9.1 12.7 33 32 A K H X S+ 0 0 66 -4,-2.1 4,-2.1 -5,-0.2 -2,-0.2 0.929 111.1 45.3 -61.7 -47.4 16.9 10.2 11.6 34 33 A V H X S+ 0 0 31 -4,-2.5 4,-2.1 2,-0.2 -2,-0.2 0.907 111.0 53.6 -62.6 -43.0 18.2 9.4 15.1 35 34 A A H X>S+ 0 0 0 -4,-2.3 5,-2.4 -5,-0.2 4,-0.8 0.932 109.4 48.6 -57.3 -45.5 16.3 6.1 15.1 36 35 A I H ><5S+ 0 0 0 -4,-2.5 3,-0.8 1,-0.2 -1,-0.2 0.921 109.7 52.3 -61.3 -42.9 17.9 5.1 11.8 37 36 A D H 3<5S+ 0 0 90 -4,-2.1 -1,-0.2 1,-0.2 -2,-0.2 0.877 110.1 47.4 -61.9 -41.1 21.4 6.0 13.0 38 37 A V H 3<5S- 0 0 55 -4,-2.1 -1,-0.2 -5,-0.1 -2,-0.2 0.523 130.8 -86.8 -85.3 -4.6 21.2 3.9 16.1 39 38 A G T <<5S+ 0 0 23 -4,-0.8 -3,-0.2 -3,-0.8 2,-0.2 0.382 74.5 142.6 124.5 -4.7 19.8 0.9 14.3 40 39 A Y < + 0 0 0 -5,-2.4 -1,-0.3 -6,-0.2 -23,-0.1 -0.480 16.2 174.4 -63.1 136.1 16.1 1.0 13.9 41 40 A R + 0 0 69 -25,-0.6 33,-2.4 -2,-0.2 2,-0.4 0.120 59.8 67.6-127.6 18.2 15.0 -0.4 10.5 42 41 A H E - e 0 74B 1 31,-0.2 -24,-2.2 -26,-0.2 2,-0.4 -0.993 57.3-173.5-144.2 126.3 11.3 -0.3 11.0 43 42 A I E -ce 18 75B 0 31,-1.7 33,-2.2 -2,-0.4 2,-0.6 -0.993 15.6-145.3-124.0 130.4 9.1 2.8 11.4 44 43 A D E +ce 19 76B 4 -26,-3.0 -24,-0.6 -2,-0.4 2,-0.2 -0.879 30.8 167.5 -98.9 119.7 5.4 2.7 12.3 45 44 A C - 0 0 0 31,-2.6 2,-0.3 -2,-0.6 3,-0.1 -0.702 17.8-170.4-122.4 169.4 3.4 5.4 10.5 46 45 A A > > - 0 0 0 -2,-0.2 3,-1.5 31,-0.2 5,-0.5 -0.913 31.5-129.3-159.9 145.0 -0.2 6.4 9.9 47 46 A H G > 5S+ 0 0 36 31,-1.0 3,-2.0 -2,-0.3 5,-0.2 0.909 111.3 58.4 -52.1 -43.1 -2.0 9.0 7.8 48 47 A V G 3 5S+ 0 0 30 1,-0.3 -1,-0.3 30,-0.3 31,-0.0 0.628 88.2 72.9 -70.6 -11.2 -4.0 10.0 10.8 49 48 A Y G < 5S- 0 0 38 -3,-1.5 -1,-0.3 -28,-0.1 -27,-0.2 0.602 95.0-141.8 -78.4 -9.9 -0.8 10.9 12.7 50 49 A Q T < 5S+ 0 0 146 -3,-2.0 -2,-0.1 -4,-0.3 -3,-0.1 0.702 78.7 84.7 64.0 26.6 -0.6 13.9 10.5 51 50 A N >< + 0 0 0 -5,-0.5 4,-1.8 -4,-0.1 5,-0.2 0.150 40.6 116.5-143.1 18.9 3.2 13.8 10.2 52 51 A E H > S+ 0 0 4 -5,-0.2 4,-2.5 1,-0.2 5,-0.2 0.856 76.5 58.6 -67.5 -31.3 3.9 11.3 7.4 53 52 A N H > S+ 0 0 73 1,-0.2 4,-1.6 2,-0.2 -1,-0.2 0.947 107.8 45.5 -57.6 -45.9 5.5 14.1 5.3 54 53 A E H > S+ 0 0 52 1,-0.2 4,-1.3 2,-0.2 -1,-0.2 0.816 111.2 52.1 -74.5 -29.0 8.1 14.8 8.0 55 54 A V H X S+ 0 0 0 -4,-1.8 4,-2.1 2,-0.2 -1,-0.2 0.911 108.6 52.8 -63.5 -43.8 8.8 11.1 8.5 56 55 A G H X S+ 0 0 0 -4,-2.5 4,-2.6 1,-0.2 -2,-0.2 0.821 103.2 56.9 -63.7 -32.9 9.4 10.8 4.8 57 56 A V H X S+ 0 0 46 -4,-1.6 4,-2.4 2,-0.2 -1,-0.2 0.922 107.4 48.3 -62.8 -43.8 11.9 13.7 4.9 58 57 A A H X S+ 0 0 0 -4,-1.3 4,-2.0 2,-0.2 -2,-0.2 0.935 113.5 46.7 -62.4 -46.9 14.0 11.8 7.5 59 58 A I H X S+ 0 0 0 -4,-2.1 4,-2.1 1,-0.2 -2,-0.2 0.938 112.4 50.1 -59.3 -49.8 13.9 8.6 5.4 60 59 A Q H X S+ 0 0 91 -4,-2.6 4,-2.4 1,-0.2 -1,-0.2 0.902 110.2 50.1 -58.5 -43.7 14.8 10.4 2.2 61 60 A E H X S+ 0 0 62 -4,-2.4 4,-2.1 2,-0.2 -1,-0.2 0.874 109.7 49.9 -65.3 -37.0 17.7 12.2 3.8 62 61 A K H <>S+ 0 0 17 -4,-2.0 5,-2.6 2,-0.2 6,-1.0 0.855 111.1 50.1 -71.3 -32.9 19.2 9.0 5.3 63 62 A L H ><5S+ 0 0 54 -4,-2.1 3,-1.2 3,-0.2 -2,-0.2 0.918 112.1 47.6 -64.7 -44.4 18.9 7.3 1.9 64 63 A R H 3<5S+ 0 0 99 -4,-2.4 -2,-0.2 1,-0.3 -1,-0.2 0.864 109.2 53.8 -64.6 -35.9 20.6 10.3 0.2 65 64 A E T 3<5S- 0 0 97 -4,-2.1 -1,-0.3 -5,-0.2 -2,-0.2 0.465 111.5-123.1 -75.8 -2.8 23.3 10.2 2.9 66 65 A Q T < 5S+ 0 0 177 -3,-1.2 -3,-0.2 2,-0.2 3,-0.1 0.847 74.2 130.2 59.4 35.6 23.9 6.5 2.1 67 66 A V S - 0 0 64 -2,-0.3 3,-1.6 -3,-0.1 4,-0.4 -0.776 30.5-115.9-100.7 154.2 19.3 1.4 1.5 70 69 A R G > S+ 0 0 31 -2,-0.3 3,-1.9 1,-0.3 -1,-0.1 0.904 115.0 57.9 -54.4 -42.4 15.5 1.3 0.9 71 70 A E G 3 S+ 0 0 147 1,-0.3 -1,-0.3 3,-0.1 0, 0.0 0.609 100.4 58.7 -67.1 -12.0 15.4 -2.5 1.0 72 71 A E G < S+ 0 0 112 -3,-1.6 2,-0.3 2,-0.0 -1,-0.3 0.530 95.1 79.2 -92.4 -10.0 16.9 -2.4 4.5 73 72 A L < - 0 0 3 -3,-1.9 2,-0.5 -4,-0.4 -31,-0.2 -0.746 64.2-154.3-100.6 149.2 14.0 -0.3 5.9 74 73 A F E -e 42 0B 8 -33,-2.4 -31,-1.7 -2,-0.3 2,-0.5 -0.922 17.4-171.2-122.9 101.9 10.6 -1.7 6.8 75 74 A I E -e 43 0B 0 -2,-0.5 31,-1.9 -33,-0.2 32,-1.4 -0.849 1.5-171.4-106.4 128.5 8.0 1.1 6.5 76 75 A V E +ef 44 107B 0 -33,-2.2 -31,-2.6 -2,-0.5 2,-0.3 -0.931 8.9 167.3-118.8 134.3 4.5 0.6 7.8 77 76 A S E - f 0 108B 0 30,-1.9 32,-2.4 -2,-0.4 2,-0.4 -0.823 22.1-129.6-136.2-177.6 1.4 2.8 7.4 78 77 A K E - f 0 109B 1 -2,-0.3 -31,-1.0 30,-0.2 2,-0.5 -0.996 14.5-121.2-143.1 137.5 -2.3 2.4 7.9 79 78 A L E - f 0 110B 0 30,-3.2 32,-1.8 -2,-0.4 33,-0.4 -0.651 37.6-126.4 -77.1 124.5 -5.5 3.1 6.0 80 79 A W > - 0 0 8 -2,-0.5 3,-2.1 31,-0.1 36,-0.1 -0.361 19.6-110.6 -77.3 155.3 -7.7 5.6 7.9 81 80 A C G > S+ 0 0 0 1,-0.3 35,-2.8 2,-0.1 3,-0.9 0.686 112.6 62.3 -57.6 -27.9 -11.4 4.7 8.7 82 81 A T G 3 S+ 0 0 3 1,-0.2 -1,-0.3 33,-0.2 37,-0.2 0.484 100.3 56.5 -79.4 -1.3 -12.9 7.2 6.3 83 82 A Y G < + 0 0 70 -3,-2.1 -1,-0.2 1,-0.1 9,-0.2 0.027 66.1 112.7-117.5 25.6 -11.3 5.4 3.3 84 83 A H < + 0 0 1 -3,-0.9 53,-0.2 32,-0.3 60,-0.1 0.710 46.3 108.4 -72.7 -20.3 -12.7 1.9 3.8 85 84 A E S >> S- 0 0 43 -3,-0.2 3,-2.5 1,-0.1 4,-0.9 -0.380 79.8-123.8 -59.1 133.7 -14.8 2.1 0.6 86 85 A K H >> S+ 0 0 108 1,-0.3 3,-0.6 2,-0.2 4,-0.5 0.821 110.1 53.6 -50.4 -37.9 -13.2 -0.1 -2.1 87 86 A G H 34 S+ 0 0 77 1,-0.2 -1,-0.3 2,-0.1 4,-0.3 0.577 110.1 47.4 -76.2 -10.8 -12.9 2.8 -4.5 88 87 A L H <> S+ 0 0 66 -3,-2.5 4,-1.8 -5,-0.1 -1,-0.2 0.559 89.2 82.7-103.7 -12.3 -11.0 5.0 -2.0 89 88 A V H S+ 0 0 40 -4,-0.3 4,-1.6 1,-0.2 -1,-0.2 0.823 109.2 52.1 -64.8 -34.1 -6.0 6.6 -3.5 92 91 A A H X S+ 0 0 10 -4,-1.8 4,-1.9 2,-0.2 -1,-0.2 0.895 111.0 48.1 -67.4 -40.9 -5.5 6.7 0.3 93 92 A C H X S+ 0 0 0 -4,-2.0 4,-2.5 1,-0.2 -2,-0.2 0.915 110.7 50.4 -64.5 -44.8 -2.4 4.4 -0.1 94 93 A Q H X S+ 0 0 96 -4,-2.6 4,-2.3 2,-0.2 -1,-0.2 0.824 107.9 54.0 -63.9 -32.8 -1.0 6.6 -2.9 95 94 A K H X S+ 0 0 105 -4,-1.6 4,-2.5 2,-0.2 -1,-0.2 0.923 109.6 47.2 -66.9 -44.6 -1.5 9.7 -0.7 96 95 A T H X S+ 0 0 0 -4,-1.9 4,-2.8 2,-0.2 -2,-0.2 0.909 112.6 49.8 -59.8 -43.8 0.5 8.1 2.1 97 96 A L H X>S+ 0 0 10 -4,-2.5 5,-2.1 2,-0.2 4,-1.0 0.900 111.2 49.3 -62.4 -42.0 3.2 7.0 -0.4 98 97 A S H <5S+ 0 0 86 -4,-2.3 3,-0.3 3,-0.2 -2,-0.2 0.920 113.2 46.6 -63.0 -45.3 3.4 10.5 -1.8 99 98 A D H <5S+ 0 0 26 -4,-2.5 -2,-0.2 1,-0.2 -43,-0.2 0.919 117.2 42.4 -62.5 -44.8 3.7 12.0 1.7 100 99 A L H <5S- 0 0 1 -4,-2.8 -1,-0.2 -5,-0.2 -2,-0.2 0.601 106.6-130.4 -78.2 -10.4 6.3 9.5 2.8 101 100 A K T <5 + 0 0 62 -4,-1.0 2,-0.3 -3,-0.3 -3,-0.2 0.863 60.8 135.2 59.7 42.4 8.1 9.9 -0.6 102 101 A L < - 0 0 17 -5,-2.1 -1,-0.2 -6,-0.2 -2,-0.1 -0.839 59.9-142.3-119.6 155.3 8.3 6.2 -1.2 103 102 A D S S+ 0 0 147 -2,-0.3 2,-0.3 1,-0.2 -1,-0.1 0.686 87.3 2.0 -81.8 -25.6 7.6 3.9 -4.1 104 103 A Y - 0 0 41 -7,-0.1 2,-0.3 3,-0.0 50,-0.3 -0.986 64.9-124.7-156.2 159.4 6.1 1.2 -1.9 105 104 A L B -k 154 0C 0 48,-2.0 50,-2.3 -2,-0.3 51,-0.3 -0.855 13.0-144.7-103.2 148.8 5.2 0.3 1.7 106 105 A D S S+ 0 0 6 -31,-1.9 2,-0.3 -2,-0.3 -30,-0.2 0.762 89.9 8.6 -78.6 -25.0 6.5 -2.8 3.3 107 106 A L E -f 76 0B 0 -32,-1.4 -30,-1.9 48,-0.2 2,-0.5 -0.944 62.4-169.0-158.2 129.5 3.2 -3.2 5.2 108 107 A Y E -fg 77 157B 2 48,-1.8 50,-2.0 -2,-0.3 2,-0.3 -0.993 16.6-164.5-125.6 124.9 -0.1 -1.4 5.0 109 108 A L E -fg 78 158B 0 -32,-2.4 -30,-3.2 -2,-0.5 2,-0.8 -0.803 29.3-118.5-110.5 147.5 -2.7 -2.0 7.7 110 109 A I E -fg 79 159B 0 48,-1.9 50,-1.1 -2,-0.3 -30,-0.1 -0.778 33.1-147.5 -75.1 116.7 -6.4 -1.4 8.0 111 110 A H S S- 0 0 15 -32,-1.8 -1,-0.2 -2,-0.8 -31,-0.1 0.877 73.0 -0.6 -62.0 -44.4 -6.1 1.0 11.0 112 111 A W - 0 0 19 -33,-0.4 -1,-0.2 2,-0.1 49,-0.1 -0.977 67.0-124.3-139.9 153.1 -9.5 -0.0 12.6 113 112 A P S S+ 0 0 1 0, 0.0 2,-0.6 0, 0.0 197,-0.1 0.669 88.1 93.9 -68.5 -15.4 -12.1 -2.6 11.5 114 113 A T - 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0 0 10 -2,-0.4 4,-2.1 -3,-0.1 3,-0.4 -0.331 33.6 -96.5 -80.4 173.5 -10.6 -9.2 17.3 164 163 A H H > S+ 0 0 32 152,-1.7 4,-2.4 1,-0.2 5,-0.1 0.795 123.8 54.7 -70.0 -25.4 -10.2 -12.9 16.6 165 164 A L H > S+ 0 0 60 2,-0.2 4,-1.8 1,-0.2 -1,-0.2 0.833 108.3 50.2 -72.0 -33.3 -13.6 -13.3 15.0 166 165 A Q H > S+ 0 0 12 -3,-0.4 4,-1.7 2,-0.2 -2,-0.2 0.887 111.4 47.4 -69.8 -40.4 -12.8 -10.4 12.6 167 166 A V H X S+ 0 0 0 -4,-2.1 4,-2.8 1,-0.2 5,-0.2 0.949 111.7 51.5 -60.8 -47.4 -9.5 -12.1 11.7 168 167 A E H X S+ 0 0 84 -4,-2.4 4,-1.5 1,-0.2 -2,-0.2 0.856 105.2 56.6 -58.1 -36.7 -11.4 -15.4 11.3 169 168 A M H < S+ 0 0 84 -4,-1.8 -1,-0.2 2,-0.2 -2,-0.2 0.923 110.4 43.1 -63.1 -45.5 -13.8 -13.6 9.0 170 169 A I H >< S+ 0 0 0 -4,-1.7 3,-1.9 1,-0.2 -2,-0.2 0.925 110.5 55.8 -63.1 -45.6 -11.0 -12.5 6.7 171 170 A L H 3< S+ 0 0 34 -4,-2.8 -1,-0.2 1,-0.3 -2,-0.2 0.793 114.9 40.5 -60.1 -25.6 -9.3 -15.9 6.8 172 171 A N T 3< S+ 0 0 120 -4,-1.5 -1,-0.3 -5,-0.2 -2,-0.2 0.236 84.8 138.4-106.3 12.3 -12.6 -17.5 5.6 173 172 A K X - 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