==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=22-APR-2012 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER IMMUNE SYSTEM 20-DEC-11 3V6O . COMPND 2 MOLECULE: LEPTIN RECEPTOR; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR B.CARPENTER,G.R.HEMSWORTH,R.J.ROSS,P.J.ARTYMIUK . 1226 17 16 13 3 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 56529.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 748 61.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 24 2.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 472 38.5 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 13 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 10 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 8 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 106 8.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 87 7.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 27 2.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 11 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 3 2 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 7 13 17 9 14 19 1 1 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 2 1 13 5 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 431 A N 0 0 157 0, 0.0 2,-0.5 0, 0.0 84,-0.1 0.000 360.0 360.0 360.0 -67.4 39.0 30.9 2.0 2 432 A I - 0 0 26 84,-0.1 2,-0.4 74,-0.1 74,-0.1 -0.882 360.0-147.6-117.4 115.4 42.5 31.7 0.3 3 433 A N - 0 0 53 -2,-0.5 2,-0.5 17,-0.2 17,-0.4 -0.547 10.1-167.7 -83.2 126.3 44.8 34.3 2.0 4 434 A I - 0 0 12 -2,-0.4 2,-0.4 15,-0.1 15,-0.2 -0.958 8.4-174.3-110.1 118.6 47.0 36.4 -0.4 5 435 A S E -A 18 0A 56 13,-2.5 13,-2.6 -2,-0.5 2,-0.3 -0.927 3.7-164.6-118.2 149.7 49.8 38.4 1.4 6 436 A a E -A 17 0A 10 -2,-0.4 2,-0.4 11,-0.2 11,-0.2 -0.909 12.5-171.6-136.4 150.9 52.1 40.9 -0.3 7 437 A E E -A 16 0A 77 9,-2.5 9,-3.1 -2,-0.3 2,-0.4 -0.994 15.7-143.0-146.0 139.1 55.4 42.8 0.3 8 438 A T E -Ab 15 96A 0 87,-2.5 89,-2.3 -2,-0.4 7,-0.3 -0.792 28.5-116.3-102.1 137.9 57.1 45.6 -1.7 9 439 A D > - 0 0 30 5,-2.4 3,-1.8 -2,-0.4 5,-0.1 -0.275 24.1-113.4 -74.7 161.0 60.9 45.6 -1.9 10 440 A G T 3 S+ 0 0 21 1,-0.3 89,-0.3 88,-0.1 -1,-0.1 0.643 116.1 61.3 -76.3 -13.4 62.8 48.4 -0.4 11 441 A Y T 3 S- 0 0 154 87,-0.1 -1,-0.3 3,-0.1 -2,-0.0 0.502 105.0-129.9 -83.7 -3.3 63.9 49.6 -3.8 12 442 A L S < S+ 0 0 44 -3,-1.8 54,-0.3 2,-0.2 56,-0.1 0.803 76.2 116.7 62.3 29.9 60.2 50.2 -4.7 13 443 A T S S+ 0 0 61 1,-0.3 2,-0.3 52,-0.1 -1,-0.1 0.635 75.4 5.7-100.1 -23.3 60.7 48.2 -8.0 14 444 A K - 0 0 69 50,-0.2 -5,-2.4 51,-0.2 2,-0.4 -0.994 52.3-138.0-156.1 163.9 58.3 45.4 -7.3 15 445 A M E -AC 8 63A 0 48,-2.4 48,-3.0 -2,-0.3 2,-0.5 -0.996 20.4-157.1-124.9 131.6 55.7 43.8 -5.0 16 446 A T E -AC 7 62A 30 -9,-3.1 -9,-2.5 -2,-0.4 2,-0.4 -0.916 9.0-166.8-113.9 128.9 55.7 40.1 -4.4 17 447 A a E -AC 6 61A 0 44,-3.1 44,-2.9 -2,-0.5 2,-0.3 -0.918 1.5-165.7-120.4 151.3 52.6 38.2 -3.3 18 448 A R E +AC 5 60A 67 -13,-2.6 -13,-2.5 -2,-0.4 2,-0.3 -0.959 13.6 157.4-137.0 147.8 52.1 34.7 -1.9 19 449 A W E - C 0 59A 4 40,-1.9 40,-3.5 -2,-0.3 2,-0.3 -0.971 13.0-165.1-159.5 164.9 49.4 32.3 -1.3 20 450 A S 0 0 44 -17,-0.4 -17,-0.2 -2,-0.3 38,-0.1 -0.952 360.0 360.0-149.6 164.8 48.8 28.5 -0.8 21 451 A T 0 0 129 36,-0.4 37,-0.1 -2,-0.3 36,-0.0 0.030 360.0 360.0-107.0 360.0 46.2 25.9 -0.8 22 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 23 460 A S 0 0 132 0, 0.0 2,-0.4 0, 0.0 55,-0.0 0.000 360.0 360.0 360.0 150.9 40.8 22.1 -9.9 24 461 A T - 0 0 97 55,-0.7 55,-2.4 2,-0.0 2,-0.4 -0.857 360.0-155.7-101.1 143.7 42.8 24.8 -11.9 25 462 A L E +E 78 0B 61 -2,-0.4 2,-0.3 53,-0.2 53,-0.2 -0.950 16.2 172.5-126.5 134.3 43.9 28.0 -10.1 26 463 A Q E -E 77 0B 78 51,-1.9 51,-3.4 -2,-0.4 2,-0.3 -0.959 26.9-133.9-147.7 121.4 44.7 31.5 -11.3 27 464 A L E -EF 76 49B 1 22,-0.5 22,-1.7 -2,-0.3 2,-0.3 -0.567 28.1-170.3 -68.0 125.7 45.4 34.7 -9.4 28 465 A R E -EF 75 48B 18 47,-3.0 47,-2.1 -2,-0.3 2,-0.3 -0.940 2.1-166.6-114.4 155.3 43.5 37.6 -10.9 29 466 A Y E -EF 74 47B 26 18,-2.3 18,-2.5 -2,-0.3 2,-0.5 -0.989 15.1-158.7-143.4 147.3 43.9 41.4 -10.0 30 467 A H E -E 73 0B 5 43,-2.5 43,-3.0 -2,-0.3 2,-0.6 -0.998 17.2-150.1-121.2 122.5 42.1 44.6 -10.6 31 468 A R E -E 72 0B 10 -2,-0.5 444,-3.2 41,-0.2 41,-0.2 -0.854 10.3-143.6 -96.7 124.1 44.1 47.8 -10.3 32 469 A S - 0 0 12 39,-2.8 442,-0.1 -2,-0.6 39,-0.1 -0.495 17.0-135.5 -78.9 148.6 42.3 51.0 -9.2 33 470 A S S S+ 0 0 9 -2,-0.2 -1,-0.1 37,-0.1 441,-0.1 0.754 100.9 17.2 -68.5 -23.8 43.1 54.5 -10.5 34 471 A L S S- 0 0 34 1,-0.3 37,-2.9 37,-0.1 -2,-0.2 0.006 106.1 -60.5-119.3-126.8 42.9 55.3 -6.7 35 472 A Y - 0 0 25 190,-0.3 2,-0.4 35,-0.2 36,-0.3 0.339 65.0 -54.4-110.6-141.4 43.1 53.3 -3.5 36 473 A b - 0 0 17 53,-0.1 188,-0.2 34,-0.1 -1,-0.1 -0.927 50.1-129.2-108.3 130.8 41.1 50.5 -1.8 37 474 A S - 0 0 33 -2,-0.4 189,-0.1 2,-0.1 52,-0.1 -0.172 32.7 -98.1 -68.1 170.9 37.4 50.9 -1.1 38 475 A D S S+ 0 0 73 1,-0.2 -1,-0.1 185,-0.0 188,-0.0 0.843 116.7 29.1 -60.1 -36.5 35.8 50.3 2.4 39 476 A I S S- 0 0 88 1036,-0.0 -1,-0.2 49,-0.0 -2,-0.1 -0.980 88.1-129.8-132.0 116.8 34.9 46.8 1.2 40 477 A P - 0 0 39 0, 0.0 2,-0.3 0, 0.0 49,-0.0 -0.382 32.8-176.8 -67.3 149.1 37.0 44.8 -1.4 41 478 A S - 0 0 45 45,-0.1 2,-0.2 47,-0.1 47,-0.1 -0.978 32.8 -99.1-144.5 161.0 35.0 43.3 -4.3 42 479 A I - 0 0 56 -2,-0.3 4,-0.0 45,-0.1 3,-0.0 -0.560 41.6-156.8 -71.6 137.6 35.3 41.2 -7.4 43 480 A H - 0 0 13 -2,-0.2 860,-0.1 1,-0.1 859,-0.0 -0.960 21.5-133.5-118.6 144.6 35.5 43.3 -10.5 44 481 A P S S+ 0 0 46 0, 0.0 2,-0.7 0, 0.0 859,-0.1 0.821 94.5 66.8 -61.3 -30.0 34.5 42.4 -14.0 45 482 A I S S+ 0 0 1 857,-0.4 2,-0.3 430,-0.1 430,-0.1 -0.849 71.0 126.6 -99.0 114.2 37.7 44.0 -15.4 46 483 A S - 0 0 2 -2,-0.7 -16,-0.2 -16,-0.1 28,-0.0 -0.975 43.5-134.6-150.1 172.9 40.9 42.2 -14.3 47 484 A E E -F 29 0B 10 -18,-2.5 -18,-2.3 -2,-0.3 2,-0.1 -0.934 23.6-116.9-130.0 157.0 44.1 40.6 -15.5 48 485 A P E -F 28 0B 48 0, 0.0 2,-0.3 0, 0.0 -20,-0.2 -0.407 21.4-148.8 -84.7 164.3 45.8 37.3 -14.6 49 486 A K E -F 27 0B 49 -22,-1.7 -22,-0.5 -2,-0.1 2,-0.5 -0.993 18.7-118.0-128.3 145.5 49.3 36.8 -13.0 50 487 A D - 0 0 116 -2,-0.3 12,-0.5 12,-0.2 2,-0.4 -0.660 35.5-175.3 -74.6 126.3 51.8 34.1 -13.3 51 488 A c E -D 61 0A 24 -2,-0.5 2,-0.4 10,-0.2 10,-0.2 -0.985 8.4-155.2-124.6 145.9 52.4 32.4 -10.0 52 489 A Y E -D 60 0A 142 8,-2.2 8,-2.2 -2,-0.4 2,-0.2 -0.947 20.2-118.4-126.7 136.8 54.9 29.7 -9.3 53 490 A L E -D 59 0A 104 -2,-0.4 6,-0.2 6,-0.2 2,-0.2 -0.504 32.3-156.6 -75.3 128.6 54.9 27.0 -6.6 54 491 A Q > - 0 0 71 4,-2.6 3,-2.0 -2,-0.2 -1,-0.0 -0.629 31.2-101.4-102.6 167.4 57.9 27.4 -4.3 55 492 A S T 3 S+ 0 0 136 1,-0.3 -1,-0.1 -2,-0.2 -2,-0.0 0.761 118.6 64.2 -64.7 -23.8 59.5 24.7 -2.1 56 493 A D T 3 S- 0 0 86 2,-0.2 -1,-0.3 1,-0.1 3,-0.1 0.439 121.3-105.6 -76.7 7.8 57.8 26.0 1.0 57 494 A G S < S+ 0 0 40 -3,-2.0 -36,-0.4 1,-0.3 2,-0.4 0.486 83.6 121.8 82.9 -0.3 54.4 25.0 -0.6 58 495 A F - 0 0 82 -38,-0.1 -4,-2.6 -37,-0.1 2,-0.3 -0.797 60.5-131.6 -96.2 140.2 53.5 28.7 -1.3 59 496 A Y E -CD 19 53A 62 -40,-3.5 -40,-1.9 -2,-0.4 2,-0.4 -0.708 25.0-155.9 -77.0 141.1 52.7 30.1 -4.8 60 497 A E E -CD 18 52A 50 -8,-2.2 -8,-2.2 -2,-0.3 2,-0.4 -0.993 11.4-174.3-126.8 130.6 54.7 33.3 -5.4 61 498 A c E -CD 17 51A 1 -44,-2.9 -44,-3.1 -2,-0.4 2,-0.5 -0.958 11.7-148.0-124.1 138.9 53.6 36.1 -7.9 62 499 A I E -C 16 0A 69 -12,-0.5 2,-0.6 -2,-0.4 -46,-0.2 -0.934 6.8-164.8-117.5 126.7 55.7 39.2 -8.9 63 500 A F E -C 15 0A 5 -48,-3.0 -48,-2.4 -2,-0.5 3,-0.0 -0.949 23.5-163.5-105.1 111.1 54.2 42.6 -9.8 64 501 A Q + 0 0 130 -2,-0.6 -50,-0.2 -50,-0.2 2,-0.1 -0.974 68.3 23.8-151.5 126.0 57.1 44.6 -11.4 65 502 A P S S- 0 0 68 0, 0.0 2,-0.4 0, 0.0 -51,-0.2 0.729 91.6-150.7 -66.4 177.7 57.1 47.6 -11.9 66 503 A I - 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