==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER STRUCTURAL PROTEIN 24-JUL-07 2V70 . COMPND 2 MOLECULE: SLIT HOMOLOG 2 PROTEIN N-PRODUCT; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR C.MORLOT,S.CUSACK,A.A.MCCARTHY . 840 4 16 16 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 40082.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 571 68.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 140 16.7 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 27 3.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 4 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 106 12.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 135 16.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 39 4.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 8 8 24 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 3 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 5 3 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 505 A A 0 0 116 0, 0.0 25,-0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 145.1 22.8 -10.5 31.3 2 506 A a - 0 0 60 6,-0.1 25,-0.1 1,-0.1 2,-0.1 -0.389 360.0-113.2 -70.5 134.9 23.7 -12.1 27.9 3 507 A P > - 0 0 9 0, 0.0 3,-2.0 0, 0.0 -1,-0.1 -0.412 38.6-102.0 -70.2 151.5 22.3 -15.6 27.1 4 508 A E T 3 S+ 0 0 189 1,-0.3 -2,-0.1 -2,-0.1 0, 0.0 0.737 114.2 33.1 -52.1 -47.9 25.0 -18.3 26.9 5 509 A K T 3 S+ 0 0 76 2,-0.0 -1,-0.3 10,-0.0 2,-0.1 0.495 109.0 84.5 -89.8 -0.1 25.6 -18.8 23.2 6 510 A b < - 0 0 13 -3,-2.0 2,-0.4 9,-0.1 9,-0.2 -0.234 67.7-132.3-100.2 178.5 24.8 -15.1 22.2 7 511 A R E -A 14 0A 145 7,-1.7 7,-3.6 -2,-0.1 2,-0.6 -0.991 15.0-157.7-138.0 126.3 26.6 -11.8 22.0 8 512 A a E +A 13 0A 42 -2,-0.4 2,-0.6 5,-0.2 5,-0.2 -0.849 19.9 163.5-118.3 98.1 25.1 -8.6 23.5 9 513 A E E > -A 12 0A 177 3,-1.1 3,-1.1 -2,-0.6 2,-0.5 -0.916 69.3 -44.9-119.6 102.5 26.4 -5.3 22.2 10 514 A G T 3 S- 0 0 63 -2,-0.6 21,-0.0 1,-0.2 -2,-0.0 -0.648 121.9 -22.4 76.2-122.2 24.1 -2.4 23.0 11 515 A T T 3 S+ 0 0 80 -2,-0.5 21,-2.9 20,-0.1 22,-1.1 0.163 116.3 97.7-108.7 16.1 20.4 -3.3 22.4 12 516 A T E < -Ab 9 33A 30 -3,-1.1 -3,-1.1 20,-0.2 2,-0.6 -0.894 56.4-159.0-106.0 132.7 21.2 -6.1 20.0 13 517 A V E -Ab 8 34A 0 20,-2.8 22,-2.7 -2,-0.4 2,-0.6 -0.952 14.2-161.7-110.6 111.9 21.4 -9.8 21.0 14 518 A D E +Ab 7 35A 28 -7,-3.6 -7,-1.7 -2,-0.6 22,-0.1 -0.833 26.1 161.4-102.7 115.7 23.4 -11.7 18.5 15 519 A b + 0 0 0 20,-2.4 3,-0.3 -2,-0.6 5,-0.2 -0.184 28.6 150.6-124.8 40.1 23.0 -15.5 18.4 16 520 A S + 0 0 11 1,-0.2 22,-0.2 -9,-0.1 23,-0.1 -0.253 58.4 7.0 -63.4 154.9 24.5 -16.1 14.9 17 521 A N S S+ 0 0 108 20,-0.8 -1,-0.2 21,-0.1 22,-0.2 0.845 83.6 126.1 37.1 66.9 26.3 -19.2 13.7 18 522 A Q S S- 0 0 60 -3,-0.3 21,-0.1 20,-0.3 -1,-0.1 0.300 75.6-115.3-135.3 10.5 25.7 -21.3 16.8 19 523 A K + 0 0 164 19,-0.5 2,-0.3 1,-0.2 20,-0.1 0.928 56.3 178.9 55.2 50.4 24.2 -24.5 15.4 20 524 A L + 0 0 25 -5,-0.2 20,-1.0 1,-0.1 -1,-0.2 -0.704 34.6 175.3 -99.3 138.4 21.0 -23.7 17.3 21 525 A N S S+ 0 0 105 -2,-0.3 21,-0.4 1,-0.2 2,-0.3 0.790 73.3 29.5 -93.0 -44.1 17.6 -25.5 17.6 22 526 A K S S- 0 0 115 19,-0.1 -1,-0.2 22,-0.1 3,-0.1 -0.900 93.8 -90.3-126.7 146.5 15.7 -23.5 20.1 23 527 A I - 0 0 37 -2,-0.3 4,-0.0 1,-0.1 13,-0.0 -0.341 60.8 -93.3 -56.9 133.5 15.7 -19.8 21.0 24 528 A P - 0 0 17 0, 0.0 3,-0.4 0, 0.0 -1,-0.1 -0.098 37.4-105.1 -57.7 158.6 18.3 -19.2 23.9 25 529 A E S S+ 0 0 77 1,-0.2 2,-0.6 -3,-0.1 -2,-0.1 0.848 96.0 22.8 -57.8 -62.7 17.3 -19.3 27.5 26 530 A H - 0 0 151 -25,-0.0 -1,-0.2 2,-0.0 3,-0.0 -0.684 63.2-170.8-121.1 81.7 17.1 -15.8 29.0 27 531 A I - 0 0 21 -2,-0.6 -25,-0.1 -3,-0.4 7,-0.0 -0.565 36.0-111.7 -73.2 121.1 16.7 -13.1 26.4 28 532 A P > - 0 0 13 0, 0.0 3,-2.0 0, 0.0 -1,-0.1 -0.227 18.1-126.0 -64.0 142.6 17.2 -9.7 28.3 29 533 A Q T 3 S+ 0 0 105 1,-0.3 26,-0.6 25,-0.1 27,-0.2 0.718 105.1 58.7 -64.0 -21.4 14.0 -7.7 28.7 30 534 A Y T 3 S+ 0 0 97 24,-0.1 -1,-0.3 25,-0.1 23,-0.1 0.613 77.3 131.4 -80.9 -12.9 15.6 -4.6 27.1 31 535 A T < + 0 0 0 -3,-2.0 24,-0.2 1,-0.1 -19,-0.2 -0.025 29.3 176.2 -63.8 145.5 16.5 -6.2 23.8 32 536 A A S S+ 0 0 23 -21,-2.9 25,-3.2 1,-0.3 26,-1.1 0.622 70.2 32.9-120.0 -22.7 15.6 -4.5 20.5 33 537 A E E -bc 12 58A 43 -22,-1.1 -20,-2.8 23,-0.2 2,-0.6 -0.951 63.8-165.6-139.6 114.2 17.0 -6.8 17.8 34 538 A L E -bc 13 59A 0 24,-2.0 26,-2.6 -2,-0.3 2,-0.6 -0.914 8.3-159.9-103.9 125.6 17.2 -10.6 18.2 35 539 A R E +bc 14 60A 75 -22,-2.7 -20,-2.4 -2,-0.6 26,-0.1 -0.921 28.9 153.1-112.3 113.4 19.5 -12.3 15.7 36 540 A L + 0 0 0 24,-2.6 3,-0.3 -2,-0.6 5,-0.2 0.214 33.9 132.5-117.6 11.5 18.9 -16.0 15.2 37 541 A N + 0 0 17 23,-0.4 -20,-0.8 1,-0.2 26,-0.2 -0.088 56.2 28.5 -71.9 161.2 20.2 -16.2 11.6 38 542 A N S S+ 0 0 68 24,-2.0 -19,-0.5 -22,-0.2 -20,-0.3 0.862 94.3 109.7 59.4 41.8 22.6 -18.7 10.2 39 543 A N S S- 0 0 11 23,-0.4 -1,-0.2 24,-0.3 -18,-0.1 -0.411 78.9 -96.6-120.4-159.9 21.7 -21.5 12.6 40 544 A E + 0 0 79 -20,-1.0 2,-0.3 -2,-0.2 24,-0.1 -0.393 51.2 158.9-127.2 64.4 19.9 -24.8 12.2 41 545 A F + 0 0 2 -5,-0.2 24,-1.8 1,-0.1 3,-0.1 -0.595 13.0 179.1 -72.7 139.5 16.3 -24.2 13.2 42 546 A T + 0 0 70 1,-0.4 25,-2.7 -21,-0.4 26,-0.8 0.755 67.3 9.0-107.2 -45.0 13.9 -26.7 11.7 43 547 A V E -i 68 0B 54 -22,-0.3 2,-0.8 23,-0.2 -1,-0.4 -0.998 67.7-130.9-139.0 137.7 10.5 -25.7 13.1 44 548 A L E -i 69 0B 10 24,-2.3 26,-2.8 -2,-0.4 29,-0.1 -0.820 34.0-155.7 -90.4 110.8 9.4 -22.5 14.9 45 549 A E - 0 0 127 -2,-0.8 2,-0.3 24,-0.2 27,-0.1 -0.370 27.8 -86.0 -88.2 162.5 7.4 -23.6 18.0 46 550 A A + 0 0 60 1,-0.2 27,-0.3 25,-0.1 -1,-0.1 -0.485 61.0 154.9 -62.7 122.8 4.8 -21.9 20.1 47 551 A T - 0 0 57 25,-1.7 -1,-0.2 -2,-0.3 26,-0.1 0.787 33.4-160.7-124.1 -49.0 6.8 -20.0 22.6 48 552 A G + 0 0 17 24,-0.7 3,-0.3 1,-0.1 4,-0.2 0.714 57.8 117.9 58.0 22.8 5.3 -16.9 24.3 49 553 A I > + 0 0 60 1,-0.2 3,-0.9 2,-0.1 -1,-0.1 0.655 68.9 67.2 -81.3 -19.0 8.8 -15.6 25.4 50 554 A F G > S+ 0 0 5 25,-0.3 3,-1.2 1,-0.2 -1,-0.2 0.603 78.2 81.6 -74.0 -12.5 7.9 -12.7 23.1 51 555 A K G 3 S+ 0 0 72 -3,-0.3 -1,-0.2 1,-0.3 -2,-0.1 0.817 99.1 38.0 -60.9 -31.5 5.1 -11.7 25.6 52 556 A K G < S+ 0 0 38 -3,-0.9 -1,-0.3 -4,-0.2 -2,-0.1 -0.165 92.7 88.0-118.4 39.4 7.7 -10.0 27.8 53 557 A L X + 0 0 13 -3,-1.2 3,-1.0 23,-0.2 26,-0.2 -0.578 43.3 160.4-130.7 68.7 10.1 -8.4 25.2 54 558 A P T 3 S+ 0 0 73 0, 0.0 -1,-0.1 0, 0.0 -24,-0.1 0.563 70.1 55.9 -77.6 -8.6 8.3 -5.1 24.7 55 559 A Q T 3 S+ 0 0 92 -26,-0.6 2,-0.1 -24,-0.2 -25,-0.1 0.684 77.1 113.3 -90.3 -23.8 11.4 -3.4 23.2 56 560 A L < + 0 0 3 -3,-1.0 -24,-0.2 -27,-0.2 -23,-0.2 -0.288 28.1 162.4 -56.0 120.9 12.1 -5.9 20.4 57 561 A R + 0 0 124 -25,-3.2 24,-3.7 1,-0.3 25,-1.7 0.604 61.1 34.4-116.6 -15.3 11.6 -4.4 16.9 58 562 A K E -cd 33 82A 56 -26,-1.1 -24,-2.0 23,-0.2 2,-0.4 -0.997 55.6-169.3-140.2 139.8 13.4 -6.8 14.6 59 563 A I E -cd 34 83A 0 23,-2.4 25,-2.4 -2,-0.3 2,-0.7 -0.958 11.3-153.1-132.8 124.2 13.9 -10.6 14.5 60 564 A N E +cd 35 84A 24 -26,-2.6 -24,-2.6 -2,-0.4 -23,-0.4 -0.803 29.6 154.1-103.5 106.9 16.4 -12.4 12.1 61 565 A F + 0 0 2 23,-2.5 3,-0.4 -2,-0.7 5,-0.2 0.131 30.1 143.9-106.5 14.1 15.7 -16.0 11.1 62 566 A S + 0 0 11 1,-0.2 -24,-2.0 22,-0.1 -23,-0.4 -0.129 60.1 17.0 -52.2 153.5 17.6 -15.8 7.8 63 567 A N S S+ 0 0 73 23,-1.9 -24,-0.3 -26,-0.2 -1,-0.2 0.865 89.8 117.2 48.7 51.4 19.5 -18.8 6.7 64 568 A N S S- 0 0 14 23,-1.0 -1,-0.1 -3,-0.4 -24,-0.1 -0.397 72.3-110.6-110.4-156.3 18.1 -21.6 8.7 65 569 A K + 0 0 75 -24,-1.8 2,-0.6 -2,-0.2 23,-0.1 -0.500 48.2 166.7-134.2 67.5 16.2 -24.6 7.5 66 570 A I + 0 0 0 -5,-0.2 23,-1.5 1,-0.2 -23,-0.2 -0.748 14.2 170.1 -88.1 117.4 12.7 -23.9 8.7 67 571 A T + 0 0 73 -25,-2.7 24,-0.7 -2,-0.6 2,-0.3 0.778 66.4 20.9 -91.9 -32.5 9.9 -26.0 7.2 68 572 A D E -i 43 0B 73 -26,-0.8 -24,-2.3 22,-0.1 2,-0.4 -0.982 53.8-155.0-139.1 149.3 7.0 -25.0 9.5 69 573 A I E -i 44 0B 5 -2,-0.3 -24,-0.2 -26,-0.2 2,-0.1 -0.993 24.9-139.1-119.6 122.9 5.9 -22.2 11.8 70 574 A E > - 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0 0 51 1,-0.1 3,-2.2 -2,-0.1 4,-0.5 -0.357 25.1-114.3 -70.0 146.9 20.7 -10.3 64.8 836 707 D I G >4 S+ 0 0 89 1,-0.3 3,-0.7 2,-0.2 -1,-0.1 0.779 113.0 62.5 -53.2 -29.1 18.2 -7.8 66.5 837 708 D Q G 34 S+ 0 0 170 1,-0.2 -1,-0.3 3,-0.0 -38,-0.1 0.674 95.7 55.6 -68.9 -23.4 21.2 -5.6 67.3 838 709 D D G <4 S+ 0 0 64 -3,-2.2 2,-1.0 -40,-0.1 -1,-0.2 0.516 77.5 94.3 -97.7 -9.0 22.3 -4.8 63.8 839 710 D F << + 0 0 12 -3,-0.7 -41,-0.2 -4,-0.5 2,-0.0 -0.792 57.4 152.4 -76.7 107.0 19.0 -3.4 62.6 840 711 D T - 0 0 80 -2,-1.0 -42,-0.1 -43,-0.6 -1,-0.1 -0.403 39.1-155.6-150.1 71.6 20.0 0.1 63.3 841 712 D p - 0 0 49 1,-0.2 2,-2.0 2,-0.0 -2,-0.0 -0.195 40.6-111.4 -47.1 126.8 18.6 3.1 61.5 842 713 D D 0 0 105 1,-0.2 -1,-0.2 0, 0.0 -2,-0.0 -0.445 360.0 360.0 -91.2 75.7 21.4 5.7 62.0 843 714 D D 0 0 149 -2,-2.0 -1,-0.2 0, 0.0 -2,-0.0 0.840 360.0 360.0 57.7 360.0 20.1 8.4 64.3