==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=5-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSFERASE 26-JUL-07 2V74 . COMPND 2 MOLECULE: HISTONE-ARGININE METHYLTRANSFERASE CARM1; . SOURCE 2 ORGANISM_SCIENTIFIC: MUS MUSCULUS; . AUTHOR W.W.YUE,M.HASSLER,S.M.ROE,V.THOMPSON-VALE,L.H.PEARL . 1329 8 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 49693.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 1024 77.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 101 7.6 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 279 21.0 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 4 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 3 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 12 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 141 10.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 187 14.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 250 18.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 10 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 1 2 4 6 7 1 6 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 4 3 5 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 12 0 5 0 3 4 6 3 11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 4 4 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 147 B A > 0 0 81 0, 0.0 4,-1.0 0, 0.0 5,-0.1 0.000 360.0 360.0 360.0 131.7 -7.3 32.9 -88.1 2 148 B V H > + 0 0 114 2,-0.2 4,-1.5 1,-0.2 5,-0.1 0.896 360.0 50.1 -74.2 -42.2 -4.3 31.8 -90.3 3 149 B Q H > S+ 0 0 75 1,-0.2 4,-1.7 2,-0.2 -1,-0.2 0.772 104.8 58.0 -69.3 -30.6 -3.0 29.4 -87.6 4 150 B Y H > S+ 0 0 44 2,-0.2 4,-1.3 1,-0.2 -1,-0.2 0.901 109.9 42.7 -65.7 -44.1 -6.4 27.7 -87.1 5 151 B F H < S+ 0 0 33 -4,-1.0 67,-0.3 2,-0.2 -2,-0.2 0.769 110.9 54.9 -77.4 -27.2 -6.7 26.6 -90.7 6 152 B Q H >< S+ 0 0 104 -4,-1.5 3,-1.3 2,-0.2 4,-0.3 0.894 104.0 58.6 -66.3 -39.5 -3.0 25.6 -90.9 7 153 B F H >< S+ 0 0 95 -4,-1.7 3,-1.1 1,-0.3 6,-0.2 0.911 108.0 42.2 -53.6 -51.9 -3.7 23.3 -87.9 8 154 B Y T 3< S+ 0 0 15 -4,-1.3 -1,-0.3 1,-0.2 -2,-0.2 0.352 100.7 76.4 -81.1 6.9 -6.5 21.3 -89.7 9 155 B G T < S+ 0 0 10 -3,-1.3 2,-0.5 63,-0.1 -1,-0.2 0.547 75.7 89.7 -90.2 -11.5 -4.3 21.3 -92.8 10 156 B Y S X> S- 0 0 49 -3,-1.1 4,-1.5 -4,-0.3 3,-1.0 -0.779 72.6-144.7 -89.8 126.8 -2.1 18.6 -91.4 11 157 B L H 3> S+ 0 0 0 -2,-0.5 4,-2.9 1,-0.3 5,-0.2 0.885 100.9 63.3 -55.0 -40.0 -3.2 15.0 -92.1 12 158 B S H 3> S+ 0 0 27 1,-0.2 4,-1.5 2,-0.2 -1,-0.3 0.818 102.9 48.6 -53.9 -37.2 -2.0 14.0 -88.6 13 159 B Q H <> S+ 0 0 53 -3,-1.0 4,-0.9 -6,-0.2 -1,-0.2 0.860 112.6 46.6 -71.5 -38.0 -4.6 16.4 -87.1 14 160 B Q H X S+ 0 0 0 -4,-1.5 4,-2.4 2,-0.2 3,-0.3 0.858 110.5 54.4 -69.7 -35.3 -7.4 14.9 -89.3 15 161 B Q H X S+ 0 0 31 -4,-2.9 4,-3.0 1,-0.2 -2,-0.2 0.886 103.0 57.1 -65.9 -39.2 -6.2 11.4 -88.4 16 162 B N H < S+ 0 0 82 -4,-1.5 4,-0.4 -5,-0.2 -1,-0.2 0.803 110.3 42.5 -63.1 -32.3 -6.4 12.2 -84.7 17 163 B M H >< S+ 0 0 9 -4,-0.9 3,-0.9 -3,-0.3 7,-0.5 0.914 115.5 49.1 -80.5 -45.1 -10.1 13.1 -85.0 18 164 B M H 3< S+ 0 0 1 -4,-2.4 -2,-0.2 1,-0.2 -3,-0.2 0.883 104.2 59.9 -56.8 -42.9 -10.9 10.2 -87.3 19 165 B Q T 3< S+ 0 0 59 -4,-3.0 2,-1.1 -5,-0.2 -1,-0.2 0.705 80.0 96.5 -62.9 -21.4 -9.1 7.8 -84.9 20 166 B D <> - 0 0 16 -3,-0.9 4,-2.4 -4,-0.4 5,-0.3 -0.611 60.9-171.0 -70.6 99.8 -11.5 8.8 -82.2 21 167 B Y H > S+ 0 0 169 -2,-1.1 4,-3.7 2,-0.2 5,-0.4 0.902 77.7 55.5 -65.8 -44.2 -13.9 5.9 -82.7 22 168 B V H > S+ 0 0 41 245,-0.3 4,-2.1 2,-0.2 5,-0.2 0.953 117.1 36.9 -55.0 -53.6 -16.7 7.2 -80.4 23 169 B R H >> S+ 0 0 0 2,-0.2 4,-2.3 1,-0.2 3,-0.7 0.998 122.9 41.3 -55.7 -72.3 -16.9 10.4 -82.3 24 170 B T H 3X S+ 0 0 0 -4,-2.4 4,-1.6 -7,-0.5 -2,-0.2 0.801 119.9 45.4 -52.7 -37.2 -16.3 9.0 -85.8 25 171 B G H 3X S+ 0 0 9 -4,-3.7 4,-2.8 -5,-0.3 -1,-0.3 0.820 108.5 54.3 -78.0 -34.3 -18.5 6.0 -85.2 26 172 B T H < S+ 0 0 1 -4,-3.0 3,-0.6 1,-0.2 -2,-0.2 0.924 119.6 45.4 -54.0 -53.1 -26.2 9.3 -90.4 32 178 B L H >< S+ 0 0 63 -4,-3.2 3,-0.7 -5,-0.3 -1,-0.2 0.783 109.8 53.4 -67.1 -30.6 -26.8 5.6 -91.5 33 179 B Q H 3< S+ 0 0 88 -4,-1.9 -1,-0.2 -5,-0.3 -2,-0.2 0.676 113.7 41.2 -87.2 -15.5 -29.6 4.9 -89.0 34 180 B N T X< S+ 0 0 0 -4,-1.2 3,-1.5 -3,-0.6 -1,-0.3 -0.479 72.6 153.0-118.6 61.1 -31.7 7.8 -90.1 35 181 B H G X> + 0 0 88 -3,-0.7 4,-4.2 1,-0.3 3,-2.5 0.762 62.3 71.5 -61.3 -31.5 -31.0 7.3 -93.8 36 182 B T G 34 S+ 0 0 65 1,-0.3 -1,-0.3 2,-0.2 -4,-0.1 0.826 88.0 64.5 -52.7 -36.7 -34.3 8.9 -94.8 37 183 B D G <4 S+ 0 0 17 -3,-1.5 -1,-0.3 -6,-0.2 -2,-0.2 0.508 122.6 18.5 -62.1 -6.3 -32.8 12.2 -93.6 38 184 B F T X4 S+ 0 0 0 -3,-2.5 3,-3.0 22,-0.2 -2,-0.2 0.601 85.6 119.1-133.2 -41.2 -30.3 11.6 -96.6 39 185 B K T 3< S- 0 0 115 -4,-4.2 23,-0.3 21,-0.3 22,-0.2 -0.080 101.7 -10.2 -42.7 114.5 -31.7 9.1 -99.1 40 186 B D T 3 S+ 0 0 87 21,-2.9 -1,-0.3 1,-0.2 22,-0.2 0.715 111.9 125.0 66.6 26.2 -31.9 11.1 -102.4 41 187 B K < - 0 0 87 -3,-3.0 22,-2.8 20,-0.0 23,-1.6 -0.526 65.3-108.9-110.5 175.4 -31.3 14.5 -100.7 42 188 B I E -a 64 0A 16 21,-0.2 65,-1.4 -2,-0.2 66,-1.1 -0.939 39.8-167.0-108.9 122.5 -28.9 17.4 -101.0 43 189 B V E -ab 65 108A 0 21,-3.1 23,-3.0 -2,-0.5 2,-0.4 -0.775 16.3-154.9-116.4 150.9 -26.4 17.7 -98.2 44 190 B L E -ab 66 109A 0 64,-1.8 66,-3.1 -2,-0.3 2,-0.5 -0.998 5.2-166.3-123.3 126.1 -24.0 20.3 -97.0 45 191 B D E -ab 67 110A 0 21,-3.2 23,-2.8 -2,-0.4 2,-0.7 -0.968 13.0-151.2-108.4 121.2 -20.9 19.3 -95.0 46 192 B V E S-a 68 0A 2 64,-1.7 66,-0.5 -2,-0.5 23,-0.1 -0.843 78.9 -3.0-102.4 114.6 -19.3 22.3 -93.3 47 193 B G S S- 0 0 3 21,-2.1 22,-0.3 -2,-0.7 -1,-0.3 0.969 75.7-177.4 68.6 61.5 -15.5 21.9 -92.8 48 194 B C > + 0 0 0 20,-1.8 3,-3.4 -3,-0.5 4,-0.4 0.554 7.3 179.8 -71.0 -11.9 -15.4 18.4 -94.2 49 195 B G T 3 S+ 0 0 0 1,-0.3 28,-0.3 19,-0.2 -1,-0.2 -0.229 76.2 8.3 52.8-115.6 -11.6 17.9 -93.6 50 196 B S T 3 S- 0 0 1 1280,-0.2 -1,-0.3 -36,-0.1 30,-0.2 0.680 108.6-111.3 -63.8 -22.1 -10.7 14.5 -94.8 51 197 B G S <> S+ 0 0 4 -3,-3.4 4,-1.5 -4,-0.1 3,-0.4 0.357 75.1 138.0 104.8 2.7 -14.2 14.2 -96.2 52 198 B I H > + 0 0 1 -4,-0.4 4,-1.5 1,-0.2 5,-0.1 0.806 66.3 47.1 -57.7 -39.5 -15.2 11.6 -93.7 53 199 B L H > S+ 0 0 0 -5,-0.4 4,-2.0 1,-0.2 -1,-0.2 0.886 109.3 54.4 -73.3 -36.5 -18.8 12.9 -92.9 54 200 B S H > S+ 0 0 0 -3,-0.4 4,-2.5 2,-0.2 -1,-0.2 0.807 104.3 55.8 -64.4 -30.5 -19.7 13.4 -96.5 55 201 B F H X S+ 0 0 3 -4,-1.5 4,-2.2 2,-0.2 -1,-0.2 0.935 106.4 49.2 -68.3 -43.3 -18.8 9.7 -97.2 56 202 B F H X S+ 0 0 0 -4,-1.5 4,-1.7 2,-0.2 -2,-0.2 0.893 109.8 54.2 -57.1 -41.0 -21.2 8.6 -94.5 57 203 B A H X>S+ 0 0 0 -4,-2.0 5,-1.7 1,-0.2 4,-0.8 0.937 107.0 49.8 -56.8 -49.8 -23.7 10.9 -96.3 58 204 B A H ><5S+ 0 0 6 -4,-2.5 3,-0.9 1,-0.2 -2,-0.2 0.890 108.2 53.6 -56.7 -39.1 -23.0 9.1 -99.5 59 205 B Q H 3<5S+ 0 0 77 -4,-2.2 -1,-0.2 1,-0.3 -2,-0.2 0.820 101.0 59.3 -68.6 -30.6 -23.5 5.7 -97.8 60 206 B A H 3<5S- 0 0 9 -4,-1.7 -21,-0.3 -3,-0.4 -1,-0.3 0.660 126.0-101.6 -72.6 -18.1 -26.9 6.8 -96.5 61 207 B G T <<5 + 0 0 10 -3,-0.9 -21,-2.9 -4,-0.8 -3,-0.2 0.619 60.0 168.5 108.9 19.5 -27.9 7.3 -100.2 62 208 B A < - 0 0 3 -5,-1.7 -20,-0.2 -23,-0.3 -23,-0.1 0.079 29.4-146.3 -50.2 170.7 -27.6 11.1 -100.6 63 209 B R S S+ 0 0 136 -22,-2.8 2,-0.3 1,-0.4 -21,-0.2 0.694 77.9 8.5-111.2 -36.3 -27.8 12.5 -104.1 64 210 B K E -a 42 0A 73 -23,-1.6 -21,-3.1 26,-0.0 2,-0.5 -0.963 61.3-169.1-154.7 128.6 -25.4 15.5 -103.9 65 211 B I E -ac 43 90A 0 24,-2.5 26,-2.8 -2,-0.3 2,-0.7 -0.987 9.5-156.1-128.6 121.0 -23.1 16.5 -101.1 66 212 B Y E -ac 44 91A 13 -23,-3.0 -21,-3.2 -2,-0.5 2,-0.8 -0.876 14.2-167.6 -98.7 112.0 -21.4 19.9 -100.9 67 213 B A E -ac 45 92A 0 24,-2.3 26,-3.0 -2,-0.7 2,-0.5 -0.867 1.6-163.7-110.4 103.3 -18.3 19.5 -98.8 68 214 B V E +ac 46 93A 2 -23,-2.8 -21,-2.1 -2,-0.8 -20,-1.8 -0.748 13.3 170.9 -91.3 124.9 -16.8 22.8 -97.8 69 215 B E E - c 0 94A 0 24,-1.1 26,-2.4 -2,-0.5 -2,-0.0 -0.998 18.0-170.6-129.9 138.1 -13.2 22.8 -96.5 70 216 B A + 0 0 30 -2,-0.4 26,-0.1 24,-0.2 2,-0.1 0.610 63.9 75.8-100.9 -16.6 -11.2 25.9 -95.9 71 217 B S S > S- 0 0 6 24,-0.1 3,-2.6 -63,-0.1 24,-0.2 -0.436 101.9 -91.9 -88.9 167.7 -7.8 24.3 -95.2 72 218 B T T >> S+ 0 0 85 -67,-0.3 3,-2.4 1,-0.3 4,-0.6 0.799 115.6 85.2 -31.4 -38.9 -5.3 22.7 -97.5 73 219 B M H 3> + 0 0 0 1,-0.3 4,-3.1 2,-0.2 -1,-0.3 0.719 65.9 81.8 -50.4 -26.2 -7.2 19.6 -96.6 74 220 B A H <> S+ 0 0 11 -3,-2.6 4,-1.7 1,-0.2 -1,-0.3 0.862 92.5 48.5 -40.2 -45.7 -9.6 20.5 -99.4 75 221 B Q H <> S+ 0 0 112 -3,-2.4 4,-1.7 2,-0.2 -1,-0.2 0.879 111.5 47.1 -70.0 -42.4 -7.2 18.9 -101.9 76 222 B H H X S+ 0 0 27 -4,-0.6 4,-1.7 1,-0.2 -2,-0.2 0.884 109.0 55.5 -69.2 -39.2 -6.7 15.7 -99.9 77 223 B A H X S+ 0 0 1 -4,-3.1 4,-1.4 -28,-0.3 -2,-0.2 0.917 106.7 50.6 -56.6 -45.2 -10.4 15.3 -99.5 78 224 B E H X S+ 0 0 54 -4,-1.7 4,-2.0 -5,-0.2 -1,-0.2 0.883 104.2 57.5 -64.6 -39.3 -11.0 15.5 -103.3 79 225 B V H X S+ 0 0 59 -4,-1.7 4,-2.5 1,-0.2 -1,-0.2 0.921 107.8 48.7 -51.9 -45.6 -8.3 12.8 -103.9 80 226 B L H X S+ 0 0 1 -4,-1.7 4,-1.1 1,-0.2 -1,-0.2 0.815 106.0 56.4 -68.0 -30.6 -10.4 10.5 -101.6 81 227 B V H <>S+ 0 0 1 -4,-1.4 5,-2.5 2,-0.2 -1,-0.2 0.883 111.5 44.2 -67.9 -37.4 -13.6 11.4 -103.5 82 228 B K H ><5S+ 0 0 126 -4,-2.0 3,-2.0 3,-0.2 -2,-0.2 0.960 111.3 50.0 -69.7 -54.0 -11.9 10.2 -106.8 83 229 B S H 3<5S+ 0 0 47 -4,-2.5 -1,-0.2 1,-0.3 -2,-0.2 0.692 113.1 49.9 -63.5 -17.1 -10.3 7.0 -105.5 84 230 B N T 3<5S- 0 0 32 -4,-1.1 -1,-0.3 -5,-0.2 -2,-0.2 0.341 109.9-120.3-100.5 5.1 -13.7 6.1 -104.0 85 231 B N T < 5S+ 0 0 127 -3,-2.0 -3,-0.2 1,-0.1 3,-0.1 0.876 75.5 125.5 57.9 41.8 -15.8 6.7 -107.2 86 232 B L >< + 0 0 28 -5,-2.5 4,-1.9 -6,-0.1 -4,-0.1 -0.326 29.6 107.2-122.1 47.5 -18.0 9.3 -105.5 87 233 B T T 4 S+ 0 0 91 2,-0.2 -1,-0.1 1,-0.2 -5,-0.1 0.717 72.4 69.4 -99.9 -34.3 -17.3 12.1 -108.0 88 234 B D T 4 S+ 0 0 120 -3,-0.1 -1,-0.2 1,-0.1 -2,-0.1 0.795 121.3 7.1 -11.2 -59.2 -20.8 11.3 -109.0 89 235 B R T 4 S+ 0 0 66 1,-0.1 -24,-2.5 -8,-0.1 2,-0.6 0.531 107.4 78.2-137.8 -18.5 -22.0 12.8 -105.7 90 236 B I E < -c 65 0A 5 -4,-1.9 2,-0.9 -26,-0.2 -24,-0.2 -0.900 50.1-170.3-113.9 109.1 -19.4 14.6 -103.5 91 237 B V E -c 66 0A 56 -26,-2.8 -24,-2.3 -2,-0.6 2,-0.3 -0.832 12.2-150.8-101.0 103.4 -18.5 18.1 -104.6 92 238 B V E -c 67 0A 24 -2,-0.9 -24,-0.2 -26,-0.2 -26,-0.1 -0.580 12.4-167.3 -70.6 127.7 -15.5 19.4 -102.6 93 239 B I E -c 68 0A 29 -26,-3.0 -24,-1.1 -2,-0.3 7,-0.1 -0.890 10.9-144.3-127.1 97.7 -15.8 23.1 -102.3 94 240 B P E +c 69 0A 92 0, 0.0 -24,-0.2 0, 0.0 2,-0.2 -0.330 58.1 47.4 -63.9 139.6 -12.6 24.9 -101.1 95 241 B G S S- 0 0 25 -26,-2.4 2,-0.3 -24,-0.2 -48,-0.2 -0.668 92.9 -48.1 126.5-179.9 -13.0 28.0 -98.9 96 242 B K >> - 0 0 72 -2,-0.2 4,-2.5 -26,-0.1 3,-0.6 -0.682 44.9-125.5 -85.2 143.8 -15.0 29.2 -95.9 97 243 B V T 34 S+ 0 0 8 -2,-0.3 5,-0.1 1,-0.2 -1,-0.1 0.837 113.3 57.2 -56.4 -33.5 -18.8 28.5 -95.8 98 244 B E T 34 S+ 0 0 62 1,-0.2 -1,-0.2 3,-0.1 -3,-0.0 0.888 115.2 35.0 -60.3 -39.4 -19.2 32.3 -95.2 99 245 B E T <4 S+ 0 0 144 -3,-0.6 -2,-0.2 2,-0.0 -1,-0.2 0.751 100.6 83.4 -93.9 -28.9 -17.3 33.1 -98.4 100 246 B V < - 0 0 21 -4,-2.5 2,-0.5 -7,-0.1 -5,-0.1 -0.177 66.9-134.2 -74.5 170.4 -18.3 30.4 -100.9 101 247 B S - 0 0 106 2,-0.0 -3,-0.1 0, 0.0 -1,-0.0 -0.936 13.1-158.8-129.3 106.7 -21.3 30.2 -103.1 102 248 B L - 0 0 16 -2,-0.5 -36,-0.0 -5,-0.1 -9,-0.0 -0.576 18.7-134.7 -74.8 147.5 -23.2 26.9 -103.3 103 249 B P S S+ 0 0 103 0, 0.0 2,-0.3 0, 0.0 -1,-0.1 0.413 79.9 25.9 -83.7 4.8 -25.4 26.5 -106.3 104 250 B E S S- 0 0 79 29,-0.0 2,-0.3 0, 0.0 -2,-0.1 -0.969 79.4-100.7-163.8 157.9 -28.4 25.2 -104.4 105 251 B Q - 0 0 82 -2,-0.3 2,-0.3 29,-0.0 29,-0.2 -0.725 42.5-129.8 -95.0 149.7 -30.2 25.0 -101.1 106 252 B V E - 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