==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 20-JAN-04 1V93 . COMPND 2 MOLECULE: 5,10-METHYLENETETRAHYDROFOLATE REDUCTASE; . SOURCE 2 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS; . AUTHOR Y.NAKAJIMA,I.MIYAHARA,K.HIROTSU,RIKEN STRUCTURAL GENOMICS/PR . 292 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 14380.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 204 69.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 37 12.7 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 12 4.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 29 9.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 114 39.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 5 1.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 1 0 0 2 0 1 1 4 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 1 3 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A M 0 0 101 0, 0.0 2,-0.2 0, 0.0 100,-0.1 0.000 360.0 360.0 360.0 18.8 73.7 94.2 73.1 2 2 A K >> - 0 0 38 1,-0.1 4,-2.0 140,-0.1 3,-0.8 -0.475 360.0-135.8 -69.1 133.4 72.7 96.3 70.0 3 3 A I H 3> S+ 0 0 0 1,-0.3 4,-2.5 2,-0.2 5,-0.3 0.855 104.4 65.5 -57.3 -34.4 74.0 99.8 70.2 4 4 A R H 3> S+ 0 0 61 1,-0.2 4,-1.5 2,-0.2 -1,-0.3 0.910 108.8 38.1 -53.5 -44.8 70.6 101.0 69.0 5 5 A D H <> S+ 0 0 82 -3,-0.8 4,-2.2 2,-0.2 -1,-0.2 0.821 111.0 58.6 -77.4 -33.8 69.1 99.7 72.3 6 6 A L H < S+ 0 0 55 -4,-2.0 -2,-0.2 1,-0.2 -1,-0.2 0.890 108.9 46.4 -63.2 -38.8 72.1 100.8 74.4 7 7 A L H >< S+ 0 0 5 -4,-2.5 3,-1.1 2,-0.2 -2,-0.2 0.932 112.2 48.7 -68.9 -47.6 71.5 104.4 73.3 8 8 A K H 3< S+ 0 0 189 -4,-1.5 -2,-0.2 -5,-0.3 -1,-0.2 0.866 119.7 37.3 -62.5 -37.6 67.8 104.4 73.8 9 9 A A T 3< S+ 0 0 85 -4,-2.2 -1,-0.2 -5,-0.1 -2,-0.2 0.187 86.2 139.5-101.9 17.4 68.0 102.9 77.3 10 10 A R < - 0 0 91 -3,-1.1 -3,-0.1 -4,-0.1 4,-0.0 -0.247 44.8-155.5 -64.3 149.5 71.1 104.7 78.5 11 11 A R S S- 0 0 241 1,-0.2 -1,-0.1 2,-0.1 -4,-0.1 0.410 80.3 -18.2-100.1 -5.1 71.3 106.1 82.1 12 12 A G S S- 0 0 27 255,-0.1 -1,-0.2 0, 0.0 255,-0.0 -0.944 104.7 -36.0-179.8-179.6 73.9 108.6 81.0 13 13 A P - 0 0 73 0, 0.0 255,-0.3 0, 0.0 2,-0.3 -0.289 63.7-119.7 -59.8 137.0 76.4 109.3 78.1 14 14 A L E -a 268 0A 23 253,-2.6 255,-2.4 29,-0.1 2,-0.5 -0.602 17.3-146.5 -82.5 136.6 78.0 106.1 76.7 15 15 A F E +a 269 0A 21 27,-0.4 29,-3.1 -2,-0.3 30,-0.7 -0.873 29.2 159.8-100.8 131.2 81.8 105.6 76.8 16 16 A S E -ab 270 45A 1 253,-1.8 255,-2.4 -2,-0.5 2,-0.3 -0.969 14.9-170.7-146.1 158.3 83.3 103.8 73.8 17 17 A F E -ab 271 46A 0 28,-0.9 30,-2.5 -2,-0.3 2,-0.3 -0.962 14.5-129.0-148.3 164.9 86.7 103.5 72.3 18 18 A E E +ab 272 47A 23 253,-2.6 255,-1.2 -2,-0.3 257,-0.6 -0.901 20.7 174.0-121.4 146.3 88.4 102.0 69.2 19 19 A F E - b 0 48A 2 28,-2.1 30,-2.8 -2,-0.3 -2,-0.0 -0.946 21.9-131.6-142.1 162.0 91.4 99.8 68.7 20 20 A F - 0 0 86 -2,-0.3 30,-0.1 28,-0.2 28,-0.0 -0.901 32.1-101.3-117.7 146.6 93.0 98.1 65.7 21 21 A P - 0 0 10 0, 0.0 39,-0.1 0, 0.0 38,-0.1 -0.526 45.2-125.6 -67.6 120.2 94.1 94.4 65.4 22 22 A P - 0 0 2 0, 0.0 253,-0.0 0, 0.0 -3,-0.0 -0.177 4.7-142.7 -62.7 157.1 97.9 94.3 65.9 23 23 A K S S+ 0 0 197 36,-0.0 3,-0.0 1,-0.0 36,-0.0 0.279 79.7 36.4-105.4 9.9 100.2 92.7 63.4 24 24 A D S > S- 0 0 50 1,-0.1 4,-2.1 0, 0.0 5,-0.1 -0.978 84.5-106.0-155.0 163.5 102.6 91.3 65.9 25 25 A P H > S+ 0 0 86 0, 0.0 4,-2.8 0, 0.0 5,-0.2 0.871 119.0 54.5 -61.0 -38.9 102.8 89.6 69.4 26 26 A E H > S+ 0 0 127 1,-0.2 4,-2.1 2,-0.2 5,-0.2 0.900 109.0 49.5 -62.3 -39.9 104.2 92.8 71.0 27 27 A G H > S+ 0 0 18 2,-0.2 4,-2.3 1,-0.2 -1,-0.2 0.910 110.8 49.1 -64.9 -42.7 101.3 94.7 69.6 28 28 A E H X S+ 0 0 59 -4,-2.1 4,-2.5 2,-0.2 -2,-0.2 0.914 109.9 51.3 -62.9 -43.9 98.8 92.1 71.0 29 29 A E H X S+ 0 0 150 -4,-2.8 4,-1.5 1,-0.2 -1,-0.2 0.910 111.9 47.1 -60.1 -42.8 100.5 92.3 74.4 30 30 A A H X S+ 0 0 52 -4,-2.1 4,-1.8 1,-0.2 -1,-0.2 0.885 111.6 50.9 -66.7 -39.7 100.2 96.1 74.4 31 31 A L H X S+ 0 0 0 -4,-2.3 4,-3.1 1,-0.2 5,-0.2 0.903 105.1 56.2 -65.6 -41.1 96.6 96.0 73.3 32 32 A F H X S+ 0 0 63 -4,-2.5 4,-2.2 1,-0.2 -1,-0.2 0.902 108.5 47.7 -58.2 -40.6 95.6 93.5 76.0 33 33 A R H X S+ 0 0 178 -4,-1.5 4,-2.2 2,-0.2 -1,-0.2 0.889 112.0 50.0 -67.2 -39.2 97.0 95.9 78.6 34 34 A T H X S+ 0 0 7 -4,-1.8 4,-2.5 241,-0.2 5,-0.3 0.920 110.4 49.4 -65.4 -42.7 95.1 98.8 77.0 35 35 A L H X S+ 0 0 4 -4,-3.1 4,-2.4 1,-0.2 -2,-0.2 0.913 110.4 51.5 -62.9 -41.5 91.8 96.8 77.0 36 36 A E H X S+ 0 0 146 -4,-2.2 4,-0.9 -5,-0.2 -1,-0.2 0.929 112.5 45.3 -60.7 -46.6 92.3 95.8 80.6 37 37 A E H < S+ 0 0 42 -4,-2.2 3,-0.3 1,-0.2 -2,-0.2 0.903 118.3 40.5 -66.8 -42.6 92.8 99.5 81.7 38 38 A L H >< S+ 0 0 0 -4,-2.5 3,-2.0 1,-0.2 -1,-0.2 0.789 103.4 66.9 -79.1 -26.5 89.9 100.9 79.7 39 39 A K H >< S+ 0 0 100 -4,-2.4 3,-2.1 1,-0.3 -1,-0.2 0.826 88.8 70.0 -60.5 -30.3 87.5 98.1 80.4 40 40 A A T 3< S+ 0 0 29 -4,-0.9 252,-2.8 -3,-0.3 -1,-0.3 0.630 92.0 58.9 -62.2 -14.6 87.6 99.3 84.0 41 41 A F T < S- 0 0 3 -3,-2.0 -1,-0.3 250,-0.2 -2,-0.2 0.230 114.1-116.5-100.6 13.0 85.7 102.4 82.8 42 42 A R < - 0 0 115 -3,-2.1 -27,-0.4 1,-0.1 -3,-0.1 0.933 31.0-154.6 57.6 60.2 82.8 100.4 81.6 43 43 A P - 0 0 19 0, 0.0 30,-0.3 0, 0.0 -27,-0.2 -0.396 11.5-145.1 -65.3 140.0 82.7 101.0 77.8 44 44 A A S S- 0 0 21 -29,-3.1 2,-0.3 1,-0.3 -28,-0.2 0.807 82.3 -8.1 -73.2 -31.3 79.2 100.5 76.2 45 45 A F E -b 16 0A 1 -30,-0.7 -28,-0.9 27,-0.1 2,-0.4 -0.977 64.3-137.8-159.9 159.3 80.9 99.1 73.1 46 46 A V E -bc 17 74A 0 27,-2.9 29,-2.4 -2,-0.3 -28,-0.2 -0.979 17.9-138.2-131.2 121.3 84.4 98.7 71.6 47 47 A S E -bc 18 75A 0 -30,-2.5 -28,-2.1 -2,-0.4 2,-0.6 -0.500 6.1-155.7 -78.3 142.8 85.2 99.4 68.0 48 48 A I E -bc 19 76A 1 27,-2.2 29,-2.0 -2,-0.2 -28,-0.2 -0.951 20.5-134.9-121.0 105.6 87.6 97.1 66.0 49 49 A T - 0 0 41 -30,-2.8 2,-0.6 -2,-0.6 27,-0.0 -0.260 16.2-128.3 -59.0 145.2 89.2 99.0 63.2 50 50 A Y - 0 0 13 -30,-0.1 3,-0.2 26,-0.1 28,-0.1 -0.887 24.5-116.2-103.8 119.4 89.2 97.2 59.8 51 51 A G > - 0 0 17 -2,-0.6 3,-1.8 1,-0.2 28,-0.2 -0.110 49.7 -76.0 -50.3 147.4 92.6 96.9 58.1 52 52 A A G > S- 0 0 66 1,-0.3 3,-2.1 2,-0.2 -1,-0.2 -0.187 110.1 -10.4 -51.5 127.5 92.8 98.7 54.8 53 53 A M G 3 S- 0 0 71 1,-0.3 -1,-0.3 -3,-0.2 -2,-0.1 0.761 126.1 -60.7 52.3 33.3 91.1 96.8 52.0 54 54 A G G X S+ 0 0 8 -3,-1.8 3,-1.6 1,-0.1 4,-0.3 0.587 92.0 144.4 75.1 11.0 90.6 93.7 54.1 55 55 A S T < S+ 0 0 88 -3,-2.1 -2,-0.1 1,-0.3 -3,-0.1 0.722 82.4 20.9 -54.2 -26.7 94.3 93.2 54.6 56 56 A T T >> S+ 0 0 41 -5,-0.1 4,-1.5 1,-0.1 3,-1.0 -0.014 79.8 132.5-134.3 32.8 93.8 91.9 58.2 57 57 A R H <> S+ 0 0 78 -3,-1.6 4,-2.3 1,-0.3 5,-0.2 0.856 72.7 56.5 -54.0 -41.3 90.2 90.8 58.2 58 58 A E H 3> S+ 0 0 141 -4,-0.3 4,-2.4 1,-0.2 -1,-0.3 0.851 106.3 52.5 -61.0 -32.3 90.9 87.4 59.8 59 59 A R H <> S+ 0 0 93 -3,-1.0 4,-2.5 2,-0.2 -1,-0.2 0.859 106.5 52.6 -69.9 -37.3 92.5 89.4 62.7 60 60 A S H X S+ 0 0 0 -4,-1.5 4,-2.4 2,-0.2 -2,-0.2 0.917 111.3 46.3 -64.2 -43.7 89.3 91.5 63.0 61 61 A V H X S+ 0 0 2 -4,-2.3 4,-2.0 2,-0.2 5,-0.2 0.938 111.0 53.1 -63.8 -45.2 87.3 88.4 63.3 62 62 A A H X S+ 0 0 26 -4,-2.4 4,-2.3 1,-0.2 -2,-0.2 0.921 114.5 41.0 -55.3 -47.8 89.8 86.9 65.8 63 63 A W H X S+ 0 0 8 -4,-2.5 4,-2.6 2,-0.2 5,-0.3 0.822 107.4 60.3 -73.0 -32.0 89.5 90.0 68.0 64 64 A A H X S+ 0 0 0 -4,-2.4 4,-0.7 1,-0.2 -1,-0.2 0.909 113.2 40.3 -60.9 -39.2 85.7 90.4 67.6 65 65 A Q H >X S+ 0 0 90 -4,-2.0 4,-1.1 -5,-0.2 3,-0.5 0.931 114.5 53.4 -72.7 -46.1 85.5 87.0 69.2 66 66 A R H 3X S+ 0 0 119 -4,-2.3 4,-0.6 1,-0.2 3,-0.3 0.855 103.9 52.1 -60.0 -42.4 88.2 87.5 71.7 67 67 A I H 3<>S+ 0 0 0 -4,-2.6 5,-2.9 1,-0.2 3,-0.3 0.782 102.1 61.6 -69.9 -23.8 86.9 90.7 73.3 68 68 A Q H X<5S+ 0 0 54 -4,-0.7 3,-1.8 -3,-0.5 -1,-0.2 0.896 101.8 51.3 -66.6 -39.0 83.5 89.1 73.9 69 69 A S H 3<5S+ 0 0 91 -4,-1.1 -1,-0.2 -3,-0.3 -2,-0.2 0.676 105.9 57.1 -69.8 -17.0 85.2 86.6 76.2 70 70 A L T 3<5S- 0 0 48 -4,-0.6 -1,-0.3 -3,-0.3 -2,-0.2 0.343 126.8-105.7 -92.1 3.5 86.7 89.6 77.9 71 71 A G T < 5S+ 0 0 59 -3,-1.8 2,-0.3 1,-0.3 -3,-0.2 0.700 76.8 134.8 80.6 21.0 83.2 90.8 78.5 72 72 A L < - 0 0 13 -5,-2.9 -1,-0.3 -6,-0.1 -2,-0.1 -0.796 55.3-127.8-106.6 148.4 83.3 93.6 75.9 73 73 A N - 0 0 22 -2,-0.3 -27,-2.9 -30,-0.3 2,-0.2 -0.821 30.8-139.1 -96.4 106.6 80.6 94.4 73.3 74 74 A P E -c 46 0A 0 0, 0.0 2,-0.7 0, 0.0 28,-0.5 -0.429 19.2-168.1 -74.6 133.6 82.2 94.6 69.8 75 75 A L E -cd 47 102A 0 -29,-2.4 -27,-2.2 -2,-0.2 2,-0.5 -0.941 24.6-152.9-114.6 98.5 81.4 97.1 67.1 76 76 A A E -cd 48 103A 0 26,-2.3 28,-2.4 -2,-0.7 2,-0.2 -0.673 1.8-144.8 -82.3 120.8 83.1 95.5 64.1 77 77 A H E - d 0 104A 8 -29,-2.0 2,-0.3 -2,-0.5 28,-0.2 -0.562 20.6-179.7 -80.5 147.6 84.2 97.8 61.3 78 78 A L E - d 0 105A 2 26,-2.0 28,-3.0 -2,-0.2 2,-0.2 -0.937 6.7-169.4-153.3 126.1 83.9 96.6 57.8 79 79 A T - 0 0 10 -2,-0.3 28,-0.3 -28,-0.2 29,-0.2 -0.664 20.5-146.0-110.4 167.7 84.9 98.4 54.5 80 80 A V > + 0 0 0 27,-0.9 3,-1.3 26,-0.4 40,-0.4 0.493 59.1 120.1-110.0 -9.2 84.2 97.5 50.9 81 81 A A T 3 S+ 0 0 2 26,-2.0 -2,-0.1 1,-0.2 28,-0.1 -0.229 81.7 0.6 -61.0 143.2 87.4 98.8 49.4 82 82 A G T 3 S+ 0 0 34 36,-0.3 2,-0.3 1,-0.1 -1,-0.2 0.640 112.2 97.7 54.4 20.1 89.7 96.5 47.5 83 83 A Q S < S- 0 0 1 -3,-1.3 37,-0.4 41,-0.2 41,-0.3 -0.980 75.5-113.7-137.3 147.6 87.4 93.5 48.1 84 84 A S > - 0 0 15 -2,-0.3 4,-2.3 39,-0.2 39,-0.3 -0.394 34.5-110.5 -74.4 158.2 84.8 91.8 45.9 85 85 A R H > S+ 0 0 117 37,-2.8 4,-2.7 1,-0.2 5,-0.2 0.892 121.3 55.3 -55.1 -39.2 81.2 92.1 47.1 86 86 A K H > S+ 0 0 163 36,-0.4 4,-1.7 2,-0.2 -1,-0.2 0.895 105.9 49.0 -61.0 -44.4 81.4 88.3 47.8 87 87 A E H > S+ 0 0 58 2,-0.2 4,-2.1 1,-0.2 5,-0.2 0.914 112.4 49.4 -62.7 -43.0 84.5 88.7 50.0 88 88 A V H X S+ 0 0 0 -4,-2.3 4,-2.4 1,-0.2 -2,-0.2 0.944 110.1 49.4 -61.1 -49.8 82.7 91.5 51.9 89 89 A A H X S+ 0 0 13 -4,-2.7 4,-1.6 1,-0.2 -1,-0.2 0.815 109.9 54.3 -60.2 -31.5 79.6 89.4 52.4 90 90 A E H X S+ 0 0 119 -4,-1.7 4,-1.9 2,-0.2 -1,-0.2 0.938 109.9 42.6 -69.7 -49.6 81.7 86.5 53.7 91 91 A V H X S+ 0 0 7 -4,-2.1 4,-2.1 1,-0.2 -2,-0.2 0.882 111.4 57.8 -65.1 -36.6 83.5 88.4 56.4 92 92 A L H X S+ 0 0 0 -4,-2.4 4,-2.0 -5,-0.2 -1,-0.2 0.905 107.2 48.0 -58.3 -41.5 80.2 90.1 57.3 93 93 A H H X S+ 0 0 86 -4,-1.6 4,-2.9 1,-0.2 -1,-0.2 0.879 107.4 54.9 -68.7 -37.6 78.8 86.6 57.9 94 94 A R H X S+ 0 0 105 -4,-1.9 4,-0.9 2,-0.2 -1,-0.2 0.865 108.2 50.3 -63.4 -36.1 81.8 85.5 60.0 95 95 A F H ><>S+ 0 0 2 -4,-2.1 5,-2.2 2,-0.2 3,-1.1 0.985 115.0 40.9 -63.9 -58.4 81.2 88.5 62.3 96 96 A V H ><5S+ 0 0 9 -4,-2.0 3,-1.8 1,-0.3 -2,-0.2 0.884 112.9 55.3 -56.1 -41.7 77.5 87.8 62.8 97 97 A E H 3<5S+ 0 0 141 -4,-2.9 -1,-0.3 1,-0.3 -2,-0.2 0.742 104.8 55.9 -64.5 -22.6 78.2 84.1 63.1 98 98 A S T <<5S- 0 0 28 -3,-1.1 -1,-0.3 -4,-0.9 -2,-0.2 0.315 129.1 -94.7 -92.9 7.4 80.7 85.0 65.8 99 99 A G T < 5S+ 0 0 33 -3,-1.8 2,-0.4 1,-0.3 -3,-0.2 0.530 72.3 152.3 93.9 5.9 78.0 86.8 67.9 100 100 A V < + 0 0 2 -5,-2.2 -1,-0.3 -6,-0.2 -25,-0.1 -0.577 15.0 172.1 -73.3 127.4 78.7 90.3 66.6 101 101 A E + 0 0 55 -27,-0.4 42,-3.0 -2,-0.4 2,-0.4 0.343 60.1 64.4-115.9 2.4 75.5 92.4 66.8 102 102 A N E +de 75 143A 0 -28,-0.5 -26,-2.3 40,-0.2 2,-0.4 -0.989 58.5 179.6-134.0 126.5 77.0 95.8 65.9 103 103 A L E -de 76 144A 0 40,-2.5 42,-2.9 -2,-0.4 2,-0.7 -0.957 21.6-150.9-127.2 142.5 78.6 96.8 62.6 104 104 A L E -de 77 145A 8 -28,-2.4 -26,-2.0 -2,-0.4 2,-0.6 -0.934 23.3-150.4-111.4 104.4 80.2 100.0 61.3 105 105 A A E +d 78 0A 0 40,-2.1 42,-0.5 -2,-0.7 2,-0.3 -0.685 26.9 166.3 -81.1 119.3 79.6 100.0 57.6 106 106 A L - 0 0 30 -28,-3.0 -26,-0.4 -2,-0.6 -25,-0.1 -0.874 41.2-143.7-131.7 162.2 82.4 101.9 55.7 107 107 A R - 0 0 41 -2,-0.3 -26,-2.0 -28,-0.3 -27,-0.9 0.883 43.4-140.5 -89.7 -46.5 83.7 102.3 52.2 108 108 A G - 0 0 21 -29,-0.2 -26,-0.1 -28,-0.2 19,-0.1 -0.104 24.4 -72.4 99.8 157.3 87.4 102.6 53.1 109 109 A D - 0 0 110 1,-0.1 -56,-0.1 -28,-0.1 3,-0.1 -0.258 52.6 -91.8 -82.8 170.2 90.0 104.9 51.6 110 110 A P - 0 0 19 0, 0.0 -1,-0.1 0, 0.0 7,-0.1 -0.253 60.7 -76.8 -71.2 171.0 91.6 104.7 48.1 111 111 A P > - 0 0 27 0, 0.0 3,-1.8 0, 0.0 5,-0.1 -0.258 67.1 -76.3 -64.7 161.2 94.8 102.7 47.8 112 112 A R T 3 S+ 0 0 244 1,-0.3 3,-0.1 -3,-0.1 0, 0.0 -0.294 121.6 24.3 -58.2 139.0 98.0 104.4 49.0 113 113 A G T 3 S+ 0 0 80 1,-0.2 2,-0.4 -3,-0.1 -1,-0.3 0.452 102.4 104.3 85.0 -0.1 99.2 107.0 46.6 114 114 A E < - 0 0 67 -3,-1.8 -1,-0.2 1,-0.1 4,-0.1 -0.955 45.7-174.3-118.7 132.9 95.8 107.5 45.1 115 115 A R S S+ 0 0 229 -2,-0.4 2,-0.5 1,-0.1 -1,-0.1 0.629 72.5 62.8 -98.5 -16.8 93.5 110.5 45.9 116 116 A V S S- 0 0 113 -5,-0.1 -1,-0.1 -7,-0.1 2,-0.0 -0.951 87.2-120.7-115.0 124.0 90.4 109.4 44.0 117 117 A F - 0 0 14 -2,-0.5 -2,-0.1 -7,-0.1 -8,-0.1 -0.305 27.9-178.2 -64.6 140.0 88.7 106.2 45.1 118 118 A R - 0 0 145 -4,-0.1 -36,-0.3 -2,-0.0 2,-0.0 -0.994 21.5-131.5-136.0 133.2 88.3 103.3 42.7 119 119 A P - 0 0 31 0, 0.0 6,-0.1 0, 0.0 -38,-0.1 -0.260 34.4 -80.9 -81.9 172.4 86.4 100.1 43.8 120 120 A H > - 0 0 47 4,-0.5 3,-2.4 -37,-0.4 -35,-0.1 -0.436 49.3-109.1 -65.5 146.5 87.4 96.5 43.4 121 121 A P T 3 S+ 0 0 123 0, 0.0 -1,-0.1 0, 0.0 -37,-0.1 0.796 121.5 24.7 -50.1 -27.6 86.6 95.4 39.9 122 122 A E T 3 S+ 0 0 127 2,-0.1 -37,-2.8 0, 0.0 -36,-0.4 -0.061 111.8 95.0-127.8 32.1 83.8 93.3 41.5 123 123 A G S < S- 0 0 6 -3,-2.4 -39,-0.2 -39,-0.3 -42,-0.1 -0.583 76.1 -83.1-118.7-179.1 83.2 95.3 44.7 124 124 A F - 0 0 21 -41,-0.3 -4,-0.5 -44,-0.3 -41,-0.2 -0.335 23.3-158.5 -77.3 164.1 80.9 98.0 46.1 125 125 A R S S+ 0 0 111 1,-0.2 2,-0.3 -6,-0.1 -1,-0.1 0.639 70.6 41.8-116.0 -25.9 81.7 101.7 45.6 126 126 A Y S >> S- 0 0 141 1,-0.1 3,-1.2 -20,-0.0 4,-0.7 -0.948 71.1-128.6-129.0 148.4 79.8 103.3 48.5 127 127 A A H >> S+ 0 0 9 -2,-0.3 4,-2.0 1,-0.3 3,-1.0 0.842 107.7 67.6 -58.8 -34.0 79.3 102.6 52.2 128 128 A A H 3> S+ 0 0 29 1,-0.3 4,-2.4 2,-0.2 -1,-0.3 0.837 93.2 59.4 -56.4 -32.9 75.5 102.9 51.7 129 129 A E H <> S+ 0 0 70 -3,-1.2 4,-1.8 1,-0.2 -1,-0.3 0.845 105.8 47.3 -65.7 -33.4 75.7 99.8 49.6 130 130 A L H < S- 0 0 26 -4,-2.1 3,-2.0 -5,-0.3 -3,-0.2 0.483 80.1-164.0-129.4 -6.5 69.9 90.4 58.6 139 139 A G G >< S- 0 0 31 -4,-2.5 3,-0.6 -5,-0.4 -1,-0.2 -0.291 72.1 -20.5 58.1-135.9 67.3 93.1 59.1 140 140 A D G 3 S+ 0 0 112 1,-0.2 -1,-0.3 3,-0.1 -5,-0.1 0.180 107.6 106.4 -91.5 16.9 67.2 94.6 62.6 141 141 A R G < S+ 0 0 138 -3,-2.0 2,-0.3 -6,-0.1 -1,-0.2 0.704 88.8 30.3 -66.2 -19.7 69.1 91.5 63.9 142 142 A V S < S- 0 0 1 -3,-0.6 2,-0.4 -4,-0.1 -40,-0.2 -0.924 82.0-122.9-136.2 161.2 72.1 93.8 64.1 143 143 A S E -e 102 0A 0 -42,-3.0 -40,-2.5 -2,-0.3 2,-0.4 -0.906 28.5-155.7-107.3 133.4 72.7 97.6 64.7 144 144 A V E -e 103 0A 0 -2,-0.4 31,-3.2 29,-0.3 32,-1.2 -0.923 10.5-174.4-117.7 136.1 74.6 99.5 62.0 145 145 A G E -ef 104 176A 0 -42,-2.9 -40,-2.1 -2,-0.4 2,-0.3 -0.815 4.4-161.8-121.4 162.7 76.6 102.7 62.2 146 146 A G E - f 0 177A 0 30,-1.2 32,-2.1 -2,-0.3 2,-0.2 -0.923 26.4 -93.3-140.4 165.5 78.3 104.9 59.7 147 147 A A E - f 0 178A 13 -42,-0.5 2,-0.3 -2,-0.3 32,-0.2 -0.573 33.0-166.4 -82.9 141.9 81.0 107.6 59.4 148 148 A A E - f 0 179A 0 30,-1.9 32,-2.1 -2,-0.2 15,-0.0 -0.945 9.7-147.7-125.2 147.3 80.0 111.3 59.5 149 149 A Y > - 0 0 49 -2,-0.3 3,-1.9 30,-0.2 4,-0.2 -0.838 11.4-174.3-124.1 95.9 82.3 114.2 58.6 150 150 A P T 3 S+ 0 0 15 0, 0.0 -1,-0.1 0, 0.0 3,-0.1 0.811 95.7 35.5 -53.4 -33.3 81.9 117.5 60.5 151 151 A E T 3 S- 0 0 62 1,-0.1 37,-0.0 40,-0.0 8,-0.0 0.248 126.4 -95.3-107.3 13.0 84.4 119.2 58.2 152 152 A G < - 0 0 12 -3,-1.9 -1,-0.1 7,-0.1 7,-0.1 0.402 39.4 -81.7 86.0 138.6 83.5 117.2 55.0 153 153 A H > - 0 0 28 -4,-0.2 3,-1.8 1,-0.1 72,-0.1 -0.544 42.4-120.2 -72.2 137.7 84.9 114.1 53.5 154 154 A P T 3 S+ 0 0 80 0, 0.0 -1,-0.1 0, 0.0 71,-0.1 0.754 110.6 48.6 -48.1 -32.0 88.1 114.9 51.5 155 155 A E T 3 S+ 0 0 65 7,-0.0 2,-0.1 3,-0.0 -2,-0.0 0.572 82.3 114.0 -90.0 -10.5 86.5 113.6 48.3 156 156 A S < - 0 0 32 -3,-1.8 3,-0.1 1,-0.1 4,-0.0 -0.364 63.9-139.6 -64.8 139.8 83.2 115.3 48.4 157 157 A E S S- 0 0 180 1,-0.2 2,-0.3 -2,-0.1 -1,-0.1 0.763 81.9 -10.9 -68.7 -28.9 82.5 117.9 45.7 158 158 A S S > S- 0 0 59 1,-0.1 4,-2.5 0, 0.0 -1,-0.2 -0.962 70.3-105.3-162.6 164.8 80.9 120.3 48.1 159 159 A L H > S+ 0 0 92 -2,-0.3 4,-2.2 2,-0.2 5,-0.2 0.845 120.4 56.0 -68.7 -32.6 79.7 120.3 51.7 160 160 A E H > S+ 0 0 130 2,-0.2 4,-2.2 1,-0.2 -1,-0.2 0.936 110.9 44.2 -63.2 -45.9 76.1 120.2 50.4 161 161 A A H > S+ 0 0 2 1,-0.2 4,-2.7 2,-0.2 5,-0.2 0.909 109.8 56.2 -64.1 -43.1 76.9 117.1 48.5 162 162 A D H X S+ 0 0 9 -4,-2.5 4,-1.6 1,-0.2 -1,-0.2 0.905 111.2 44.1 -55.4 -42.8 78.8 115.6 51.4 163 163 A L H X S+ 0 0 21 -4,-2.2 4,-2.6 2,-0.2 -1,-0.2 0.871 110.9 53.3 -72.2 -37.5 75.6 116.1 53.6 164 164 A R H X S+ 0 0 134 -4,-2.2 4,-2.3 1,-0.2 -2,-0.2 0.925 110.4 48.0 -62.3 -44.1 73.3 114.7 50.9 165 165 A H H X S+ 0 0 102 -4,-2.7 4,-1.9 2,-0.2 -1,-0.2 0.850 110.7 51.3 -65.9 -35.8 75.4 111.6 50.6 166 166 A F H X S+ 0 0 10 -4,-1.6 4,-2.5 -5,-0.2 -2,-0.2 0.933 109.9 49.4 -66.6 -45.6 75.5 111.2 54.4 167 167 A K H X S+ 0 0 79 -4,-2.6 4,-2.9 1,-0.2 -2,-0.2 0.917 110.0 51.5 -59.2 -42.1 71.7 111.5 54.5 168 168 A A H X S+ 0 0 55 -4,-2.3 4,-1.1 1,-0.2 -1,-0.2 0.894 109.3 50.4 -61.0 -40.5 71.4 108.9 51.8 169 169 A K H < S+ 0 0 26 -4,-1.9 4,-0.4 2,-0.2 3,-0.3 0.897 110.6 49.1 -65.2 -39.9 73.6 106.6 53.8 170 170 A V H >X S+ 0 0 13 -4,-2.5 4,-2.2 1,-0.2 3,-2.2 0.945 108.3 53.8 -62.9 -46.8 71.5 107.1 56.9 171 171 A E H 3< S+ 0 0 137 -4,-2.9 -1,-0.2 1,-0.3 -2,-0.2 0.732 95.2 69.2 -59.7 -24.8 68.3 106.3 54.8 172 172 A A T 3< S- 0 0 31 -4,-1.1 -1,-0.3 -3,-0.3 -2,-0.2 0.697 133.9 -72.6 -68.1 -18.2 69.9 103.1 53.7 173 173 A G T <4 S+ 0 0 21 -3,-2.2 2,-0.3 -4,-0.4 -29,-0.3 0.685 71.9 160.1 130.9 40.2 69.5 101.9 57.3 174 174 A L < - 0 0 10 -4,-2.2 -29,-0.2 -5,-0.2 -1,-0.1 -0.709 22.9-169.2 -91.8 140.3 71.8 103.4 59.9 175 175 A D S S- 0 0 33 -31,-3.2 2,-0.3 -2,-0.3 -30,-0.2 0.700 75.0 -14.6 -92.5 -26.5 70.9 103.4 63.6 176 176 A F E -f 145 0A 0 -32,-1.2 -30,-1.2 26,-0.2 2,-0.3 -0.947 60.2-137.3-161.8 177.7 73.7 105.8 64.5 177 177 A A E -fg 146 204A 0 26,-1.7 28,-3.3 -2,-0.3 2,-0.4 -0.973 5.3-147.5-146.5 156.0 76.9 107.5 63.3 178 178 A I E -fg 147 205A 7 -32,-2.1 -30,-1.9 -2,-0.3 2,-0.1 -0.992 25.9-128.6-124.9 133.2 80.3 108.3 64.7 179 179 A T E -f 148 0A 0 26,-2.8 -30,-0.2 -2,-0.4 3,-0.1 -0.460 21.0-104.3 -86.1 157.6 82.1 111.4 63.5 180 180 A Q E - 0 0 53 -32,-2.1 27,-0.6 1,-0.2 -1,-0.1 -0.293 62.7 -75.9 -63.6 160.3 85.7 111.8 62.1 181 181 A L E - g 0 207A 8 25,-0.1 2,-0.3 27,-0.1 27,-0.2 -0.290 56.0-177.4 -64.1 147.2 87.9 113.3 64.8 182 182 A F - 0 0 1 25,-0.8 27,-0.3 -3,-0.1 3,-0.1 -0.982 24.1-158.2-144.1 152.4 87.6 117.1 65.5 183 183 A F S S+ 0 0 3 44,-0.5 2,-0.4 -2,-0.3 45,-0.1 0.435 80.6 54.9-113.9 -3.2 89.4 119.5 67.7 184 184 A N S >> S- 0 0 66 43,-0.1 3,-1.8 1,-0.1 4,-0.7 -0.986 73.0-143.7-130.1 120.0 86.9 122.4 68.1 185 185 A N H 3> S+ 0 0 1 -2,-0.4 4,-2.8 1,-0.3 5,-0.3 0.729 95.2 74.2 -55.2 -22.7 83.4 121.4 69.3 186 186 A A H 3> S+ 0 0 58 1,-0.2 4,-2.6 2,-0.2 -1,-0.3 0.878 90.5 57.7 -58.9 -36.4 81.9 124.0 67.0 187 187 A H H <> S+ 0 0 46 -3,-1.8 4,-1.8 1,-0.2 -1,-0.2 0.931 111.1 42.2 -58.8 -45.3 82.7 121.7 64.1 188 188 A Y H X S+ 0 0 7 -4,-0.7 4,-2.6 2,-0.2 -2,-0.2 0.941 114.8 47.3 -67.8 -51.8 80.5 119.0 65.7 189 189 A F H X S+ 0 0 59 -4,-2.8 4,-2.1 1,-0.2 -2,-0.2 0.896 112.8 51.5 -60.2 -37.6 77.6 121.2 66.9 190 190 A G H X S+ 0 0 35 -4,-2.6 4,-2.1 -5,-0.3 -1,-0.2 0.903 110.5 47.1 -65.6 -41.5 77.5 122.8 63.5 191 191 A F H X S+ 0 0 2 -4,-1.8 4,-2.4 -5,-0.2 -2,-0.2 0.898 109.2 55.7 -66.6 -39.8 77.4 119.5 61.7 192 192 A L H X S+ 0 0 21 -4,-2.6 4,-2.5 1,-0.2 -2,-0.2 0.925 110.7 43.8 -58.4 -46.9 74.7 118.3 64.1 193 193 A E H X S+ 0 0 130 -4,-2.1 4,-2.3 2,-0.2 -1,-0.2 0.888 111.3 53.3 -68.2 -37.2 72.5 121.2 63.2 194 194 A R H X S+ 0 0 77 -4,-2.1 4,-1.2 1,-0.2 -1,-0.2 0.895 112.0 48.1 -62.7 -37.0 73.1 120.9 59.5 195 195 A A H <>S+ 0 0 0 -4,-2.4 5,-2.7 2,-0.2 3,-0.2 0.929 110.3 48.4 -68.5 -48.0 72.1 117.3 59.9 196 196 A R H ><5S+ 0 0 82 -4,-2.5 3,-1.4 1,-0.2 -2,-0.2 0.879 110.1 53.7 -61.1 -36.8 68.9 118.0 61.8 197 197 A R H 3<5S+ 0 0 225 -4,-2.3 -1,-0.2 1,-0.3 -2,-0.2 0.837 105.3 54.4 -65.0 -33.0 68.0 120.6 59.2 198 198 A A T 3<5S- 0 0 27 -4,-1.2 -1,-0.3 -3,-0.2 -2,-0.2 0.358 126.5-102.3 -82.6 4.7 68.4 118.0 56.5 199 199 A G T < 5S+ 0 0 55 -3,-1.4 2,-0.5 1,-0.3 -3,-0.2 0.651 73.7 144.1 84.6 15.9 65.9 115.8 58.3 200 200 A I < + 0 0 6 -5,-2.7 -1,-0.3 -6,-0.1 -2,-0.1 -0.781 16.3 168.3 -91.3 127.0 68.5 113.4 59.9 201 201 A G + 0 0 65 -2,-0.5 -1,-0.1 2,-0.1 3,-0.1 0.409 33.1 114.8-119.3 3.4 67.4 112.3 63.4 202 202 A I S S- 0 0 24 1,-0.1 2,-0.2 -26,-0.1 -26,-0.2 -0.337 78.6 -90.8 -73.2 155.3 69.8 109.4 64.3 203 203 A P - 0 0 23 0, 0.0 -26,-1.7 0, 0.0 2,-0.6 -0.487 39.1-160.3 -66.7 132.5 72.3 109.8 67.2 204 204 A I E -g 177 0A 1 -28,-0.2 -26,-0.2 -2,-0.2 63,-0.2 -0.951 8.8-153.2-118.4 107.5 75.6 111.1 65.9 205 205 A L E -g 178 0A 2 -28,-3.3 -26,-2.8 -2,-0.6 2,-0.3 -0.649 15.5-120.1 -86.8 134.4 78.4 110.4 68.3 206 206 A P E - 0 0 0 0, 0.0 64,-2.4 0, 0.0 2,-0.5 -0.520 20.2-145.1 -73.7 132.7 81.5 112.7 68.5 207 207 A G E -gh 181 270A 0 -27,-0.6 -25,-0.8 -2,-0.3 2,-0.4 -0.877 20.1-170.3 -98.5 127.6 84.7 110.9 67.7 208 208 A I E - h 0 271A 0 62,-3.0 64,-2.6 -2,-0.5 -27,-0.1 -0.963 15.4-168.6-124.3 135.6 87.6 112.3 69.8 209 209 A M - 0 0 2 -2,-0.4 2,-0.3 -27,-0.3 64,-0.1 -0.929 17.1-146.2-121.4 104.9 91.4 111.7 69.5 210 210 A P - 0 0 5 0, 0.0 2,-0.2 0, 0.0 41,-0.1 -0.576 26.6-120.6 -72.0 129.9 93.4 113.0 72.4 211 211 A V + 0 0 4 39,-0.3 39,-0.2 -2,-0.3 40,-0.2 -0.508 38.2 167.7 -74.7 133.6 96.8 114.1 71.1 212 212 A T + 0 0 39 1,-0.3 2,-0.3 -2,-0.2 35,-0.2 0.412 69.7 25.3-120.9 -5.7 100.0 112.5 72.4 213 213 A S > - 0 0 44 33,-0.2 4,-1.9 1,-0.1 -1,-0.3 -0.972 66.8-129.6-159.1 144.6 102.5 113.8 69.8 214 214 A Y H > S+ 0 0 18 -2,-0.3 4,-2.5 26,-0.3 5,-0.2 0.912 111.5 52.2 -60.4 -43.8 102.8 116.8 67.5 215 215 A R H > S+ 0 0 179 1,-0.2 4,-2.8 2,-0.2 5,-0.3 0.904 106.1 54.7 -59.2 -43.7 103.6 114.5 64.5 216 216 A Q H > S+ 0 0 23 2,-0.2 4,-2.5 1,-0.2 5,-0.3 0.935 110.1 46.0 -55.0 -50.1 100.5 112.4 65.2 217 217 A L H X S+ 0 0 0 -4,-1.9 4,-2.3 2,-0.2 5,-0.3 0.955 114.0 47.2 -59.8 -52.0 98.2 115.5 65.1 218 218 A R H X S+ 0 0 113 -4,-2.5 4,-1.9 1,-0.2 -2,-0.2 0.920 116.1 43.8 -56.7 -48.1 99.8 116.9 62.0 219 219 A R H X S+ 0 0 105 -4,-2.8 4,-1.8 2,-0.2 -1,-0.2 0.896 113.4 48.9 -67.2 -43.9 99.6 113.6 60.1 220 220 A F H X S+ 0 0 80 -4,-2.5 4,-2.4 -5,-0.3 6,-0.3 0.906 115.2 44.3 -64.7 -41.8 96.1 112.6 61.1 221 221 A T H X S+ 0 0 10 -4,-2.3 4,-1.5 -5,-0.3 5,-0.3 0.867 111.1 54.4 -71.3 -35.0 94.6 116.0 60.2 222 222 A E H < S+ 0 0 130 -4,-1.9 -1,-0.2 -5,-0.3 -2,-0.2 0.882 115.2 40.0 -64.7 -38.1 96.5 116.2 56.9 223 223 A V H < S+ 0 0 92 -4,-1.8 -2,-0.2 1,-0.2 -1,-0.2 0.860 122.6 38.2 -80.3 -38.3 95.1 112.8 55.9 224 224 A C H < S- 0 0 16 -4,-2.4 -2,-0.2 -5,-0.2 -3,-0.2 0.528 103.8-122.5 -92.7 -5.6 91.6 113.2 57.2 225 225 A G < + 0 0 47 -4,-1.5 -3,-0.2 1,-0.2 -4,-0.1 0.520 60.6 145.3 79.3 5.0 91.2 116.8 56.3 226 226 A A - 0 0 11 -5,-0.3 2,-0.3 -6,-0.3 -1,-0.2 -0.348 43.9-121.4 -74.0 158.2 90.4 117.9 59.8 227 227 A S - 0 0 43 -43,-0.1 -44,-0.5 -2,-0.1 -43,-0.1 -0.693 9.0-139.1-105.0 156.3 91.5 121.3 61.1 228 228 A I - 0 0 33 -2,-0.3 -44,-0.0 -46,-0.1 2,-0.0 -0.944 26.1-118.0-113.0 126.4 93.8 122.3 64.0 229 229 A P > - 0 0 26 0, 0.0 4,-2.5 0, 0.0 5,-0.2 -0.375 24.9-123.8 -61.0 138.4 92.8 125.3 66.2 230 230 A G H > S+ 0 0 48 1,-0.2 4,-2.4 2,-0.2 5,-0.2 0.877 108.1 50.3 -52.1 -45.2 95.6 128.0 65.9 231 231 A P H > S+ 0 0 105 0, 0.0 4,-2.1 0, 0.0 -1,-0.2 0.918 112.5 45.5 -61.7 -45.1 96.2 128.1 69.7 232 232 A L H > S+ 0 0 11 1,-0.2 4,-2.7 2,-0.2 5,-0.2 0.904 112.6 52.3 -64.3 -42.6 96.5 124.4 70.1 233 233 A L H X S+ 0 0 55 -4,-2.5 4,-2.3 1,-0.2 5,-0.2 0.923 110.0 47.4 -59.1 -48.2 98.8 124.2 67.1 234 234 A A H X S+ 0 0 59 -4,-2.4 4,-2.0 -5,-0.2 -1,-0.2 0.902 113.6 48.3 -61.5 -42.2 101.1 126.9 68.5 235 235 A K H X S+ 0 0 109 -4,-2.1 4,-1.7 2,-0.2 -2,-0.2 0.931 113.7 44.9 -65.2 -48.4 101.3 125.2 71.9 236 236 A L H < S+ 0 0 0 -4,-2.7 4,-0.4 1,-0.2 -1,-0.2 0.870 112.2 52.4 -64.8 -38.4 102.0 121.7 70.6 237 237 A E H >< S+ 0 0 100 -4,-2.3 3,-0.8 -5,-0.2 4,-0.2 0.922 109.2 49.7 -65.0 -42.8 104.6 123.0 68.1 238 238 A R H 3< S+ 0 0 201 -4,-2.0 3,-0.2 1,-0.2 -1,-0.2 0.849 121.8 33.0 -64.1 -35.5 106.5 124.9 70.8 239 239 A H T >< S+ 0 0 59 -4,-1.7 3,-2.4 1,-0.2 7,-0.4 0.207 80.6 119.8-107.6 15.9 106.6 121.9 73.1 240 240 A Q T < S+ 0 0 86 -3,-0.8 -26,-0.3 -4,-0.4 -1,-0.2 0.759 72.0 55.8 -52.4 -32.4 106.8 119.1 70.5 241 241 A D T 3 S+ 0 0 149 -3,-0.2 -1,-0.3 -4,-0.2 -2,-0.1 0.433 94.2 77.6 -82.9 2.0 110.1 117.8 71.8 242 242 A D <> - 0 0 78 -3,-2.4 4,-2.7 1,-0.2 5,-0.2 -0.850 60.9-170.5-115.3 95.1 108.7 117.3 75.3 243 243 A P H > S+ 0 0 101 0, 0.0 4,-2.2 0, 0.0 -1,-0.2 0.843 87.8 49.7 -50.2 -40.5 106.6 114.1 75.4 244 244 A K H > S+ 0 0 169 2,-0.2 4,-2.0 1,-0.2 5,-0.1 0.912 111.4 46.5 -69.3 -43.9 105.2 114.9 78.9 245 245 A A H > S+ 0 0 22 1,-0.2 4,-2.7 2,-0.2 -1,-0.2 0.914 113.4 50.5 -64.6 -42.3 104.3 118.5 78.0 246 246 A V H X S+ 0 0 2 -4,-2.7 4,-3.0 -7,-0.4 5,-0.2 0.918 108.7 50.7 -61.9 -44.8 102.6 117.3 74.8 247 247 A L H X S+ 0 0 43 -4,-2.2 4,-2.7 -5,-0.2 5,-0.2 0.911 112.0 48.5 -59.3 -42.8 100.6 114.7 76.6 248 248 A E H X S+ 0 0 75 -4,-2.0 4,-2.8 2,-0.2 5,-0.3 0.930 112.4 47.8 -63.2 -47.0 99.4 117.3 79.1 249 249 A I H X S+ 0 0 16 -4,-2.7 4,-2.3 1,-0.2 -2,-0.2 0.943 115.3 45.1 -60.1 -48.9 98.4 119.7 76.4 250 250 A G H X S+ 0 0 2 -4,-3.0 4,-2.1 -39,-0.2 -39,-0.3 0.889 114.5 47.8 -63.9 -40.9 96.6 117.0 74.4 251 251 A V H X S+ 0 0 0 -4,-2.7 4,-2.9 -5,-0.2 5,-0.2 0.956 112.7 47.8 -66.4 -49.3 94.8 115.6 77.5 252 252 A E H X S+ 0 0 90 -4,-2.8 4,-2.6 1,-0.2 -2,-0.2 0.912 111.8 50.9 -57.8 -42.6 93.7 119.0 78.8 253 253 A H H X S+ 0 0 33 -4,-2.3 4,-2.2 -5,-0.3 -1,-0.2 0.920 112.7 45.5 -61.4 -44.5 92.4 120.0 75.3 254 254 A A H X S+ 0 0 2 -4,-2.1 4,-3.1 2,-0.2 5,-0.3 0.875 110.6 54.0 -66.8 -38.5 90.4 116.8 75.0 255 255 A V H X S+ 0 0 21 -4,-2.9 4,-2.9 2,-0.2 5,-0.2 0.946 109.0 48.9 -60.4 -47.3 89.1 117.2 78.6 256 256 A R H X S+ 0 0 148 -4,-2.6 4,-1.6 -5,-0.2 -2,-0.2 0.921 114.5 45.5 -58.1 -46.3 87.9 120.7 77.7 257 257 A Q H X S+ 0 0 1 -4,-2.2 4,-2.1 1,-0.2 -2,-0.2 0.965 116.0 44.4 -60.9 -54.8 86.2 119.4 74.5 258 258 A V H X S+ 0 0 2 -4,-3.1 4,-2.9 1,-0.2 5,-0.2 0.874 108.0 58.1 -61.0 -39.9 84.6 116.4 76.1 259 259 A A H X S+ 0 0 45 -4,-2.9 4,-2.0 -5,-0.3 -1,-0.2 0.930 110.5 43.2 -57.6 -45.5 83.4 118.3 79.2 260 260 A E H X S+ 0 0 91 -4,-1.6 4,-1.7 -5,-0.2 -1,-0.2 0.879 112.2 53.2 -69.0 -37.7 81.4 120.7 77.0 261 261 A L H <>S+ 0 0 0 -4,-2.1 5,-1.9 2,-0.2 4,-0.2 0.936 110.3 47.7 -63.0 -45.4 80.1 117.8 74.8 262 262 A L H ><5S+ 0 0 59 -4,-2.9 3,-1.6 1,-0.2 -2,-0.2 0.925 112.0 48.8 -61.3 -45.1 78.8 116.0 77.9 263 263 A E H 3<5S+ 0 0 169 -4,-2.0 -1,-0.2 1,-0.3 -2,-0.2 0.813 105.2 60.1 -65.1 -27.8 77.1 119.1 79.2 264 264 A A T 3<5S- 0 0 59 -4,-1.7 -1,-0.3 -5,-0.2 -2,-0.2 0.507 120.8-111.2 -77.0 -4.9 75.6 119.7 75.8 265 265 A G T < 5 + 0 0 48 -3,-1.6 -3,-0.2 -4,-0.2 -2,-0.1 0.746 49.8 174.8 84.7 24.6 73.9 116.3 76.2 266 266 A V < - 0 0 13 -5,-1.9 -1,-0.2 1,-0.1 3,-0.1 -0.315 36.9-127.1 -62.7 149.9 75.6 114.1 73.7 267 267 A E S S- 0 0 46 1,-0.2 -253,-2.6 -63,-0.2 2,-0.3 0.651 77.9 -30.8 -74.3 -13.3 74.5 110.5 73.8 268 268 A G E -a 14 0A 0 -255,-0.3 2,-0.4 -64,-0.1 -253,-0.2 -0.961 54.9-117.1 174.2 171.5 78.1 109.3 74.1 269 269 A V E -a 15 0A 5 -255,-2.4 -253,-1.8 -2,-0.3 2,-0.5 -0.997 18.3-151.3-135.8 129.4 81.8 109.9 73.2 270 270 A H E -ah 16 207A 0 -64,-2.4 -62,-3.0 -2,-0.4 2,-0.5 -0.888 13.6-150.7-103.4 120.9 83.9 107.6 71.0 271 271 A F E -ah 17 208A 4 -255,-2.4 -253,-2.6 -2,-0.5 2,-0.9 -0.807 8.7-148.7-100.7 127.0 87.7 107.6 71.7 272 272 A Y E +a 18 0A 37 -64,-2.6 -253,-0.1 -2,-0.5 -255,-0.0 -0.804 25.7 170.0 -89.3 106.4 90.4 106.9 69.1 273 273 A T > - 0 0 7 -255,-1.2 3,-2.0 -2,-0.9 -1,-0.2 0.644 34.3-141.3 -94.0 -19.0 93.1 105.3 71.3 274 274 A L T 3 S- 0 0 51 -256,-0.3 -255,-0.1 1,-0.3 3,-0.1 0.855 74.8 -61.8 55.9 33.0 95.5 104.0 68.6 275 275 A N T 3 S+ 0 0 15 -257,-0.6 2,-0.4 1,-0.2 -1,-0.3 0.599 115.0 114.9 68.8 16.1 95.8 101.0 71.0 276 276 A K < - 0 0 124 -3,-2.0 4,-0.4 1,-0.1 -1,-0.2 -0.944 46.1-167.1-118.1 138.7 97.2 103.2 73.8 277 277 A S > + 0 0 6 -2,-0.4 4,-3.1 2,-0.1 5,-0.3 0.799 66.2 80.9 -95.4 -33.0 95.4 103.8 77.1 278 278 A P H > S+ 0 0 68 0, 0.0 4,-2.6 0, 0.0 5,-0.2 0.863 95.2 44.1 -40.7 -59.4 97.2 106.7 78.9 279 279 A A H > S+ 0 0 9 2,-0.2 4,-2.0 1,-0.2 5,-0.2 0.937 118.4 42.4 -57.4 -52.4 95.7 109.6 77.1 280 280 A T H > S+ 0 0 1 -4,-0.4 4,-2.5 1,-0.2 -1,-0.2 0.925 115.5 49.3 -63.3 -44.5 92.1 108.3 77.2 281 281 A R H X S+ 0 0 65 -4,-3.1 4,-2.6 1,-0.2 -1,-0.2 0.899 110.9 50.8 -62.1 -39.0 92.4 107.2 80.8 282 282 A M H X S+ 0 0 45 -4,-2.6 4,-2.2 -5,-0.3 -1,-0.2 0.871 109.9 49.8 -66.4 -36.5 93.8 110.5 81.8 283 283 A V H X S+ 0 0 0 -4,-2.0 4,-1.3 -5,-0.2 -2,-0.2 0.948 112.6 47.0 -65.7 -47.7 90.9 112.4 80.1 284 284 A L H <>S+ 0 0 6 -4,-2.5 5,-2.4 1,-0.2 4,-0.3 0.910 114.0 47.2 -60.6 -44.6 88.3 110.2 81.8 285 285 A E H ><5S+ 0 0 51 -4,-2.6 3,-1.4 1,-0.2 -1,-0.2 0.896 109.9 52.0 -66.3 -39.1 90.0 110.6 85.2 286 286 A R H 3<5S+ 0 0 95 -4,-2.2 -1,-0.2 1,-0.3 -2,-0.2 0.742 104.8 57.4 -69.6 -20.4 90.3 114.3 84.8 287 287 A L T 3<5S- 0 0 48 -4,-1.3 -1,-0.3 -3,-0.2 -2,-0.2 0.552 129.6-100.4 -82.7 -8.7 86.6 114.4 84.0 288 288 A G T < 5S+ 0 0 51 -3,-1.4 -3,-0.2 1,-0.3 -2,-0.1 0.372 78.4 134.3 108.2 -5.3 86.0 112.7 87.3 289 289 A L < - 0 0 55 -5,-2.4 -1,-0.3 -6,-0.2 -2,-0.1 -0.455 34.7-162.7 -76.9 152.3 85.6 109.1 86.4 290 290 A R - 0 0 153 -2,-0.1 -5,-0.0 -250,-0.1 -1,-0.0 -0.989 29.1 -90.7-136.6 145.2 87.4 106.4 88.3 291 291 A P 0 0 48 0, 0.0 -250,-0.2 0, 0.0 -251,-0.1 -0.194 360.0 360.0 -53.9 139.9 88.1 102.7 87.5 292 292 A A 0 0 111 -252,-2.8 -251,-0.1 -253,-0.0 -252,-0.1 0.957 360.0 360.0 -70.6 360.0 85.5 100.2 88.6