==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=16-NOV-2012 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 09-JAN-12 3VFE . COMPND 2 MOLECULE: KALLIKREIN-6; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR X.CHEN,Y.ZHANG,T.XIA,R.WANG . 223 2 6 6 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 10296.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 141 63.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 2 0.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 79 35.4 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 4 1.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 17 7.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 22 9.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 14 6.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 4 1 3 5 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 16 A L 0 0 1 0, 0.0 3,-0.4 0, 0.0 2,-0.3 0.000 360.0 360.0 360.0 151.1 -5.0 -8.7 -6.7 2 17 A V B +A 170 0A 7 168,-2.0 168,-1.3 123,-0.2 123,-0.1 -0.716 360.0 7.4-102.6 140.5 -6.4 -11.7 -4.9 3 18 A H S S+ 0 0 91 -2,-0.3 -1,-0.2 1,-0.2 166,-0.2 0.584 98.4 108.1 74.6 12.7 -5.9 -13.0 -1.4 4 19 A G - 0 0 30 -3,-0.4 133,-0.2 166,-0.2 -1,-0.2 -0.108 57.6-135.5 -94.1-158.8 -4.0 -10.0 -0.2 5 20 A G E -B 136 0B 25 131,-2.2 131,-3.2 -3,-0.1 2,-0.1 -0.923 39.6 -57.1-150.6 175.9 -5.1 -7.3 2.2 6 21 A P E -B 135 0B 90 0, 0.0 129,-0.3 0, 0.0 128,-0.1 -0.346 59.9-117.1 -62.5 135.0 -5.0 -3.5 2.4 7 22 A a - 0 0 7 127,-2.2 2,-0.2 47,-0.1 127,-0.1 -0.313 32.3 -95.0 -66.1 151.6 -1.4 -2.1 2.3 8 23 A D > - 0 0 119 1,-0.1 3,-1.8 3,-0.1 4,-0.3 -0.512 41.4-120.4 -58.7 136.1 0.1 -0.2 5.2 9 24 A K T 3 S+ 0 0 147 1,-0.3 3,-0.4 -2,-0.2 -1,-0.1 0.754 108.0 42.8 -58.3 -28.3 -0.6 3.4 4.4 10 25 A T T 3 S+ 0 0 92 1,-0.2 -1,-0.3 2,-0.1 -2,-0.0 0.363 96.8 77.7-100.7 5.2 3.1 4.4 4.4 11 26 A S S < S+ 0 0 44 -3,-1.8 -1,-0.2 1,-0.2 -2,-0.1 0.428 87.7 52.4-101.3 0.1 4.5 1.4 2.5 12 27 A H > + 0 0 10 -3,-0.4 3,-1.4 -4,-0.3 -1,-0.2 -0.237 52.4 140.5-133.1 49.1 3.6 2.2 -1.1 13 28 A P T 3 S+ 0 0 12 0, 0.0 89,-1.3 0, 0.0 39,-0.3 0.669 76.0 55.2 -67.7 -14.4 4.8 5.8 -2.0 14 29 A Y T 3 S+ 0 0 17 87,-0.2 16,-3.0 -3,-0.1 2,-0.2 0.513 81.1 112.8 -94.2 -9.2 5.9 4.6 -5.5 15 30 A Q E < -J 29 0C 2 -3,-1.4 37,-0.6 14,-0.2 38,-0.4 -0.469 47.7-165.1 -73.3 132.4 2.5 3.2 -6.5 16 31 A A E -JK 28 51C 0 12,-2.9 12,-0.9 -2,-0.2 2,-0.5 -0.865 11.7-146.4-112.5 151.1 0.7 5.0 -9.3 17 32 A A E -JK 27 50C 0 33,-2.3 33,-3.0 -2,-0.3 2,-0.5 -0.976 13.5-153.8-112.3 131.8 -2.9 4.8 -10.4 18 33 A L E -JK 26 49C 0 8,-2.9 7,-3.6 -2,-0.5 8,-1.5 -0.921 16.2-179.6-107.8 126.0 -3.7 5.2 -14.1 19 34 A Y E -JK 24 48C 38 29,-2.9 29,-2.6 -2,-0.5 2,-0.3 -0.869 13.2-178.5-118.0 151.1 -7.1 6.4 -15.2 20 35 A T E > S+JK 23 47C 27 3,-2.1 3,-1.9 -2,-0.3 27,-0.1 -0.961 77.7 3.7-141.2 143.3 -8.8 7.1 -18.5 21 36 A S T 3 S- 0 0 114 25,-0.5 3,-0.1 -2,-0.3 26,-0.1 0.763 130.4 -61.8 58.9 25.0 -12.3 8.5 -19.0 22 38 A G T 3 S+ 0 0 60 1,-0.2 2,-0.4 26,-0.0 -1,-0.3 0.532 115.2 105.7 82.9 5.2 -12.6 8.8 -15.2 23 39 A H E < S-J 20 0C 142 -3,-1.9 -3,-2.1 1,-0.0 -1,-0.2 -0.934 79.7 -97.0-121.9 145.2 -12.2 5.0 -14.6 24 40 A L E +J 19 0C 29 -2,-0.4 -5,-0.3 -5,-0.2 3,-0.1 -0.300 42.4 168.7 -53.7 130.9 -9.3 3.0 -13.2 25 41 A L E - 0 0 18 -7,-3.6 2,-0.3 1,-0.4 151,-0.2 0.750 54.9 -34.6-111.2 -48.4 -7.2 1.5 -16.1 26 42 A b E -J 18 0C 0 -8,-1.5 -8,-2.9 149,-0.1 -1,-0.4 -0.944 54.9 -99.8-161.2 174.7 -4.1 0.1 -14.6 27 43 A G E -J 17 0C 1 149,-2.8 12,-0.3 -2,-0.3 2,-0.3 -0.336 34.9-179.0 -94.5-171.1 -1.4 0.5 -12.0 28 44 A G E -J 16 0C 0 -12,-0.9 -12,-2.9 10,-0.1 2,-0.4 -0.965 21.4-120.0-177.9 169.6 2.1 1.9 -12.4 29 45 A V E -JL 15 37C 0 8,-2.6 8,-3.0 -2,-0.3 2,-0.5 -0.989 16.9-132.7-135.3 127.4 5.3 2.7 -10.6 30 46 A L E + L 0 36C 0 -16,-3.0 74,-2.4 -2,-0.4 6,-0.2 -0.653 35.0 159.9 -75.5 122.4 7.1 6.0 -10.1 31 47 A I E + 0 0 24 4,-2.0 -1,-0.2 -2,-0.5 5,-0.2 0.447 67.2 16.7-120.6 -5.2 10.8 5.6 -11.0 32 48 A H E > S- L 0 35C 61 3,-1.2 3,-1.4 73,-0.1 -1,-0.4 -0.961 83.3-105.7-163.2 148.0 11.8 9.2 -11.5 33 49 A P T 3 S+ 0 0 46 0, 0.0 62,-3.2 0, 0.0 60,-0.1 0.812 124.6 34.9 -52.3 -26.8 10.2 12.5 -10.6 34 50 A L T 3 S+ 0 0 44 60,-0.2 57,-2.8 1,-0.1 2,-0.4 0.470 113.5 65.0-104.9 -4.6 9.2 12.8 -14.3 35 51 A W E < -LM 32 90C 4 -3,-1.4 -4,-2.0 55,-0.2 -3,-1.2 -0.970 49.0-169.1-136.4 133.9 8.5 9.2 -15.2 36 52 A V E -LM 30 89C 0 53,-2.5 53,-3.3 -2,-0.4 2,-0.4 -0.953 17.2-146.0-113.9 137.1 6.1 6.4 -14.4 37 53 A L E +LM 29 88C 0 -8,-3.0 -8,-2.6 -2,-0.4 2,-0.2 -0.831 32.9 146.1 -99.6 137.7 6.6 2.8 -15.6 38 54 A T E - M 0 87C 0 49,-2.3 49,-2.4 -2,-0.4 2,-0.2 -0.848 50.7 -64.5-151.3-172.1 3.6 0.7 -16.5 39 55 A A > - 0 0 0 -12,-0.3 3,-1.7 -2,-0.2 47,-0.3 -0.591 35.2-129.9 -84.7 146.5 2.6 -2.1 -18.9 40 56 A A G > S+ 0 0 2 1,-0.3 3,-1.8 -2,-0.2 -1,-0.1 0.835 106.7 65.2 -60.6 -32.7 2.5 -1.5 -22.7 41 57 A H G 3 S+ 0 0 27 1,-0.3 -1,-0.3 41,-0.1 135,-0.0 0.496 89.2 71.1 -74.4 2.5 -1.0 -2.9 -22.9 42 58 A b G < + 0 0 0 -3,-1.7 -1,-0.3 2,-0.0 2,-0.2 0.492 67.1 127.2 -89.2 -6.1 -2.1 -0.0 -20.8 43 59 A K < + 0 0 107 -3,-1.8 -3,-0.0 -4,-0.1 28,-0.0 -0.352 26.4 142.4 -64.4 121.4 -1.7 2.6 -23.5 44 60 A K - 0 0 108 -2,-0.2 3,-0.3 0, 0.0 -2,-0.0 -0.970 51.3 -93.6-146.0 159.1 -4.8 4.7 -24.2 45 61 A P S S+ 0 0 98 0, 0.0 0, 0.0 0, 0.0 0, 0.0 -0.300 101.6 26.7 -63.4 157.1 -5.5 8.3 -25.0 46 62 A N S S- 0 0 137 1,-0.2 -25,-0.5 22,-0.1 2,-0.3 0.916 79.6-176.6 58.7 52.6 -6.2 10.8 -22.2 47 63 A L E -K 20 0C 12 -3,-0.3 21,-0.8 21,-0.1 2,-0.5 -0.642 11.5-163.1 -83.6 137.8 -4.3 9.1 -19.5 48 64 A Q E -KN 19 67C 52 -29,-2.6 -29,-2.9 -2,-0.3 2,-0.5 -0.991 5.5-154.6-119.5 128.0 -4.4 10.6 -16.0 49 65 A V E -KN 18 66C 1 17,-3.4 17,-2.3 -2,-0.5 2,-0.5 -0.892 4.6-162.7-104.0 127.7 -1.8 9.5 -13.4 50 66 A F E -KN 17 65C 28 -33,-3.0 -33,-2.3 -2,-0.5 2,-0.3 -0.945 8.8-173.4-110.1 124.1 -2.6 9.7 -9.7 51 67 A L E +KN 16 64C 6 13,-2.5 13,-2.1 -2,-0.5 -35,-0.1 -0.775 64.4 28.8-109.7 157.6 0.3 9.6 -7.2 52 69 A G S S+ 0 0 6 -37,-0.6 2,-0.3 -39,-0.3 10,-0.2 0.683 85.0 145.2 71.0 18.2 0.2 9.4 -3.4 53 70 A K + 0 0 7 -38,-0.4 -1,-0.2 -3,-0.3 3,-0.1 -0.628 21.2 158.2 -91.0 148.5 -3.2 7.6 -3.5 54 71 A H S S+ 0 0 23 1,-0.3 80,-2.3 -2,-0.3 2,-0.5 0.540 75.1 34.2-128.5 -50.3 -4.3 4.9 -1.0 55 72 A N B > -P 133 0D 19 78,-0.2 3,-1.3 1,-0.1 -1,-0.3 -0.953 67.0-155.3-115.1 118.1 -8.1 4.9 -1.3 56 73 A L T 3 S+ 0 0 32 76,-2.9 -1,-0.1 -2,-0.5 77,-0.1 0.707 91.5 57.2 -69.7 -20.5 -9.5 5.6 -4.7 57 74 A G T 3 S+ 0 0 65 75,-0.2 -1,-0.3 2,-0.0 2,-0.2 0.665 98.3 77.2 -81.9 -15.4 -12.8 6.9 -3.4 58 75 A Q S < S- 0 0 108 -3,-1.3 2,-0.9 74,-0.2 -4,-0.1 -0.577 76.6-131.2 -98.8 156.2 -11.2 9.6 -1.2 59 76 A Q - 0 0 162 -2,-0.2 2,-0.3 -6,-0.0 -3,-0.1 -0.894 39.9-159.8-100.4 98.9 -9.7 13.0 -2.0 60 77 A E > - 0 0 22 -2,-0.9 3,-1.5 -5,-0.2 -7,-0.0 -0.601 24.0-135.0 -94.6 141.8 -6.5 12.4 -0.1 61 78 A S T 3 S+ 0 0 133 -2,-0.3 -1,-0.1 1,-0.3 -9,-0.0 0.710 106.1 54.0 -66.1 -17.8 -4.3 15.3 1.0 62 79 A S T 3 S+ 0 0 27 -10,-0.2 -1,-0.3 2,-0.0 -9,-0.1 0.559 87.9 107.0 -90.5 -10.6 -1.3 13.4 -0.2 63 80 A Q < - 0 0 20 -3,-1.5 2,-0.4 -11,-0.1 -11,-0.2 -0.342 45.3-169.5 -82.1 151.6 -2.5 12.9 -3.7 64 81 A E E -N 51 0C 48 -13,-2.1 -13,-2.5 -2,-0.1 2,-0.4 -0.997 8.9-151.3-134.0 140.0 -1.3 14.5 -6.9 65 82 A Q E +N 50 0C 91 -2,-0.4 2,-0.3 -15,-0.2 -15,-0.2 -0.925 19.5 171.8-113.7 137.7 -2.9 14.3 -10.3 66 83 A S E -N 49 0C 11 -17,-2.3 -17,-3.4 -2,-0.4 2,-0.1 -0.998 25.4-136.6-146.4 141.3 -1.0 14.7 -13.6 67 84 A S E -N 48 0C 54 -2,-0.3 25,-2.8 -19,-0.2 2,-0.4 -0.380 31.0-115.3 -79.3 169.9 -1.6 14.2 -17.3 68 85 A V E -O 91 0C 32 -21,-0.8 23,-0.2 23,-0.2 -21,-0.1 -0.908 23.8-175.7-109.9 136.3 0.9 12.5 -19.5 69 86 A V E S+ 0 0 96 21,-2.4 2,-0.3 -2,-0.4 22,-0.1 0.577 76.7 24.6-104.8 -12.8 2.7 14.4 -22.3 70 87 A R E -O 90 0C 99 20,-1.0 20,-3.3 2,-0.0 2,-0.5 -0.966 58.0-170.7-152.3 131.3 4.6 11.4 -23.7 71 88 A A E -O 89 0C 30 -2,-0.3 2,-0.8 18,-0.2 18,-0.2 -0.960 11.0-169.3-125.2 114.0 3.8 7.7 -23.6 72 89 A V E -O 88 0C 35 16,-3.2 16,-2.3 -2,-0.5 2,-0.2 -0.839 0.9-167.5-113.9 98.3 6.7 5.5 -24.9 73 90 A I E -O 87 0C 44 -2,-0.8 14,-0.2 14,-0.2 12,-0.1 -0.514 39.6 -95.8 -73.0 147.7 5.9 1.8 -25.5 74 91 A H > - 0 0 20 12,-2.1 3,-1.6 10,-0.3 -1,-0.1 -0.450 33.4-126.7 -63.8 138.1 8.8 -0.5 -26.0 75 92 A P T 3 S+ 0 0 103 0, 0.0 -1,-0.1 0, 0.0 -2,-0.1 0.802 105.1 49.1 -58.4 -30.2 9.3 -0.8 -29.8 76 93 A D T 3 S+ 0 0 103 2,-0.1 9,-0.1 8,-0.1 -2,-0.1 0.249 75.6 143.6-101.2 13.2 9.3 -4.6 -29.7 77 94 A Y < - 0 0 55 -3,-1.6 2,-0.6 9,-0.1 7,-0.2 -0.278 37.4-153.0 -55.7 130.7 6.1 -5.1 -27.6 78 95 A D B >> -Q 83 0E 74 5,-2.5 4,-2.4 1,-0.1 5,-0.6 -0.913 6.3-164.5-112.5 108.4 4.1 -8.1 -28.7 79 96 A A T 45S+ 0 0 65 -2,-0.6 -1,-0.1 1,-0.2 -2,-0.0 0.854 86.3 53.6 -63.4 -36.5 0.4 -7.8 -27.9 80 97 A A T 45S+ 0 0 95 1,-0.2 -1,-0.2 2,-0.1 -2,-0.0 0.911 124.6 22.3 -64.2 -44.4 -0.4 -11.5 -28.4 81 98 A S T 45S- 0 0 35 -3,-0.2 -2,-0.2 2,-0.1 -1,-0.2 0.554 96.7-126.3-102.6 -11.0 2.3 -12.8 -26.0 82 99 A H T ><5 + 0 0 38 -4,-2.4 3,-0.9 1,-0.2 2,-0.2 0.642 50.4 164.8 66.8 16.9 2.8 -9.8 -23.8 83 100 A D B 3 < +Q 78 0E 29 -5,-0.6 -5,-2.5 1,-0.3 -1,-0.2 -0.473 67.7 8.9 -65.3 133.1 6.5 -10.1 -24.6 84 101 A Q T 3 S+ 0 0 29 -7,-0.2 2,-1.7 1,-0.2 -10,-0.3 0.924 82.4 179.3 61.0 49.6 8.3 -6.8 -23.7 85 102 A D < + 0 0 0 -3,-0.9 2,-0.3 73,-0.2 -1,-0.2 -0.564 31.3 119.7 -85.8 79.1 5.2 -5.5 -21.9 86 103 A I + 0 0 0 -2,-1.7 -12,-2.1 -47,-0.3 2,-0.3 -1.000 34.0 178.2-150.7 140.5 6.6 -2.1 -20.8 87 104 A M E -MO 38 73C 0 -49,-2.4 -49,-2.3 -2,-0.3 2,-0.5 -0.998 19.2-141.8-144.4 140.0 5.8 1.6 -21.3 88 105 A L E -MO 37 72C 0 -16,-2.3 -16,-3.2 -2,-0.3 2,-0.6 -0.904 14.8-156.9-102.8 130.4 7.3 4.8 -19.9 89 106 A L E -MO 36 71C 0 -53,-3.3 -53,-2.5 -2,-0.5 2,-0.6 -0.935 6.7-147.4-110.5 121.6 4.9 7.6 -19.1 90 107 A R E -MO 35 70C 76 -20,-3.3 -21,-2.4 -2,-0.6 -20,-1.0 -0.768 21.2-133.4 -86.4 117.2 6.3 11.2 -19.1 91 108 A L E - O 0 68C 0 -57,-2.8 -23,-0.2 -2,-0.6 4,-0.0 -0.495 3.6-138.2 -75.1 140.0 4.4 13.2 -16.5 92 109 A A S S+ 0 0 50 -25,-2.8 -1,-0.1 1,-0.2 -24,-0.1 0.797 95.4 28.9 -68.2 -29.4 3.2 16.7 -17.6 93 110 A R S S- 0 0 95 -26,-0.4 -1,-0.2 -60,-0.1 3,-0.1 -0.996 97.5-105.2-133.8 135.3 4.3 17.9 -14.2 94 111 A P - 0 0 75 0, 0.0 -60,-0.2 0, 0.0 -2,-0.0 -0.199 48.0 -93.3 -58.4 139.9 7.1 16.6 -12.0 95 112 A A - 0 0 12 -62,-3.2 2,-1.5 -63,-0.2 6,-0.0 -0.280 28.7-130.6 -58.5 127.6 6.0 14.5 -9.0 96 113 A K - 0 0 128 -3,-0.1 -1,-0.1 6,-0.0 -45,-0.0 -0.666 35.4-144.4 -78.3 93.1 5.7 16.6 -5.9 97 114 A L + 0 0 90 -2,-1.5 2,-0.2 3,-0.1 5,-0.2 -0.220 36.0 141.3 -67.8 148.1 7.7 14.2 -3.7 98 115 A S B > -R 101 0F 58 3,-2.1 3,-0.7 -85,-0.1 -46,-0.1 -0.862 68.9 -65.9-160.7-170.2 6.8 13.7 -0.1 99 116 A E T 3 S+ 0 0 138 -2,-0.2 3,-0.1 1,-0.2 -2,-0.1 0.861 136.8 39.6 -57.4 -35.1 6.6 10.9 2.5 100 117 A L T 3 S+ 0 0 47 1,-0.2 2,-0.4 -38,-0.1 -48,-0.3 0.379 113.2 57.3-103.9 3.7 3.8 9.4 0.5 101 118 A I B < +R 98 0F 0 -3,-0.7 -3,-2.1 -50,-0.1 -87,-0.2 -0.891 67.0 142.4-134.7 105.0 5.2 10.0 -3.0 102 119 A Q - 0 0 90 -89,-1.3 -72,-0.2 -2,-0.4 2,-0.1 -0.997 46.9-114.9-142.0 142.2 8.7 8.5 -3.7 103 120 A P - 0 0 47 0, 0.0 -72,-0.3 0, 0.0 -89,-0.1 -0.413 27.9-133.0 -68.7 152.5 10.4 6.9 -6.7 104 121 A L - 0 0 11 -74,-2.4 81,-0.1 -90,-0.2 2,-0.0 -0.939 20.5-119.8-109.0 130.0 11.4 3.2 -6.4 105 122 A P - 0 0 70 0, 0.0 81,-3.2 0, 0.0 2,-0.2 -0.360 29.1-118.9 -65.5 145.1 14.9 2.1 -7.5 106 123 A L B -c 186 0B 21 79,-0.2 2,-0.9 -75,-0.1 81,-0.2 -0.556 14.5-122.8 -83.1 147.6 15.1 -0.4 -10.3 107 124 A E + 0 0 36 79,-2.7 106,-0.1 -2,-0.2 5,-0.1 -0.824 33.0 176.3 -84.8 106.9 16.7 -3.8 -9.9 108 125 A R + 0 0 154 -2,-0.9 2,-0.8 1,-0.1 -1,-0.2 0.590 55.0 86.1 -90.6 -10.2 19.4 -3.6 -12.6 109 127 A D > - 0 0 82 1,-0.1 3,-1.9 -3,-0.1 101,-0.1 -0.815 57.8-166.2 -98.0 107.6 20.9 -7.0 -11.8 110 128 A c T 3 S+ 0 0 61 -2,-0.8 -1,-0.1 1,-0.3 101,-0.1 0.672 92.1 55.9 -63.4 -17.4 19.1 -9.9 -13.5 111 129 A S T 3 S+ 0 0 100 -3,-0.0 -1,-0.3 2,-0.0 -3,-0.0 0.128 77.2 149.2-101.5 18.3 20.9 -12.2 -11.2 112 130 A A < - 0 0 16 -3,-1.9 -5,-0.0 1,-0.1 75,-0.0 -0.250 42.9-141.9 -55.7 140.1 19.6 -10.5 -8.0 113 132 A Q + 0 0 186 70,-0.0 2,-0.2 2,-0.0 -1,-0.1 0.764 65.8 102.1 -78.3 -31.2 19.2 -12.9 -5.1 114 133 A T + 0 0 59 1,-0.2 -2,-0.0 68,-0.1 68,-0.0 -0.402 32.4 165.5 -69.9 124.2 16.1 -11.8 -3.4 115 134 A T + 0 0 77 -2,-0.2 26,-2.4 25,-0.1 2,-0.6 0.475 49.9 95.3-113.6 -8.8 13.1 -14.0 -4.3 116 135 A S E +D 140 0B 73 24,-0.2 67,-0.8 22,-0.0 2,-0.2 -0.765 58.0 156.9 -82.1 121.5 10.7 -12.8 -1.5 117 136 A d E -DE 139 182B 3 22,-3.2 22,-2.0 -2,-0.6 2,-0.3 -0.778 32.8-140.9-134.3 174.3 8.6 -10.0 -3.1 118 137 A H E -DE 138 181B 31 63,-1.9 63,-2.8 20,-0.3 2,-0.3 -0.982 8.5-157.2-136.8 157.5 5.3 -8.1 -2.8 119 138 A I E -DE 137 180B 0 18,-2.1 18,-1.7 -2,-0.3 2,-0.3 -0.844 9.8-166.3-122.3 163.7 2.8 -6.8 -5.3 120 139 A L E +D 136 0B 1 59,-0.6 2,-0.3 -2,-0.3 16,-0.2 -0.988 18.8 124.5-147.7 154.4 0.2 -4.1 -5.0 121 140 A G E -D 135 0B 0 14,-1.8 14,-2.6 -2,-0.3 54,-0.1 -0.935 57.0-111.9 169.5 171.1 -2.8 -2.8 -6.8 122 141 A W S S+ 0 0 2 52,-0.5 53,-0.1 -2,-0.3 3,-0.1 0.052 73.5 125.8-106.8 20.8 -6.5 -1.7 -7.1 123 142 A G S S- 0 0 0 1,-0.2 51,-0.3 7,-0.1 50,-0.1 -0.106 72.0 -52.1 -75.6 179.3 -7.3 -4.6 -9.3 124 143 A K - 0 0 50 49,-2.6 6,-0.2 6,-0.1 -1,-0.2 -0.170 55.7-146.5 -59.5 136.7 -10.0 -7.3 -8.8 125 144 A T > - 0 0 21 4,-2.6 3,-2.2 -3,-0.1 -123,-0.2 -0.379 35.2 -87.2 -95.2 178.9 -10.0 -9.1 -5.5 126 145 A A T 3 S+ 0 0 61 -125,-0.3 -124,-0.1 1,-0.3 -2,-0.1 0.761 125.1 59.8 -61.4 -27.1 -11.0 -12.7 -4.7 127 146 A D T 3 S- 0 0 119 2,-0.1 -1,-0.3 1,-0.1 3,-0.1 0.535 117.2-112.4 -79.5 -6.3 -14.7 -11.7 -4.3 128 147 A G S < S+ 0 0 41 -3,-2.2 2,-0.1 1,-0.3 -2,-0.1 0.422 81.2 111.8 93.5 -1.5 -14.7 -10.5 -7.9 129 150 A D S S- 0 0 100 -6,-0.1 -4,-2.6 -5,-0.0 -1,-0.3 -0.446 71.1-109.9 -98.5 171.5 -15.2 -6.8 -7.0 130 151 A F - 0 0 69 -6,-0.2 -6,-0.1 -2,-0.1 -7,-0.1 -0.931 35.3-130.9-104.9 126.3 -12.8 -3.8 -7.3 131 152 A P - 0 0 21 0, 0.0 -75,-0.1 0, 0.0 4,-0.1 -0.391 9.8-150.4 -76.9 147.7 -11.4 -2.4 -4.0 132 153 A D S S+ 0 0 102 -2,-0.1 -76,-2.9 -77,-0.1 2,-0.4 0.858 86.9 63.0 -73.7 -40.6 -11.4 1.2 -2.9 133 154 A T B S-P 55 0D 37 -78,-0.2 -78,-0.2 -77,-0.1 -1,-0.1 -0.721 97.3-106.4 -96.1 134.4 -8.3 0.6 -0.8 134 155 A I - 0 0 0 -80,-2.3 -127,-2.2 -2,-0.4 2,-0.3 -0.293 36.9-141.8 -59.7 135.6 -5.0 -0.5 -2.4 135 156 A Q E -BD 6 121B 23 -14,-2.6 -14,-1.8 -129,-0.3 2,-0.3 -0.700 15.0-167.2-103.4 152.6 -4.2 -4.2 -1.8 136 157 A a E +BD 5 120B 26 -131,-3.2 -131,-2.2 -2,-0.3 2,-0.3 -0.965 6.5 177.3-134.0 150.7 -0.8 -5.8 -1.0 137 158 A A E - D 0 119B 8 -18,-1.7 -18,-2.1 -2,-0.3 2,-0.4 -0.960 27.5-124.9-154.9 140.6 0.4 -9.4 -0.9 138 159 A Y E + D 0 118B 174 -2,-0.3 2,-0.3 -20,-0.2 -20,-0.3 -0.696 39.8 163.2 -78.3 128.8 3.7 -11.2 -0.4 139 160 A I E - D 0 117B 1 -22,-2.0 -22,-3.2 -2,-0.4 2,-0.4 -0.876 28.3-124.3-138.7 175.6 4.7 -13.6 -3.2 140 161 A H E -FD 163 116B 98 23,-2.8 23,-2.4 -2,-0.3 -24,-0.2 -0.944 24.0-110.0-126.2 140.6 7.8 -15.4 -4.3 141 162 A L E -F 162 0B 24 -26,-2.4 2,-0.4 -2,-0.4 21,-0.3 -0.431 34.4-141.2 -62.3 142.4 9.7 -15.4 -7.6 142 163 A V E -F 161 0B 32 19,-3.0 19,-0.5 -2,-0.1 5,-0.1 -0.868 25.8 -99.1-109.8 141.8 9.4 -18.8 -9.3 143 164 A S > - 0 0 57 -2,-0.4 4,-2.5 1,-0.1 3,-0.3 -0.256 29.6-117.8 -65.5 149.3 12.4 -20.3 -11.1 144 165 A R H > S+ 0 0 93 1,-0.3 4,-2.4 2,-0.2 5,-0.2 0.880 117.0 50.1 -54.1 -41.7 12.4 -19.9 -14.9 145 166 A E H > S+ 0 0 117 1,-0.2 4,-1.6 2,-0.2 -1,-0.3 0.879 108.8 52.9 -67.1 -35.7 12.2 -23.6 -15.4 146 167 A E H > S+ 0 0 117 -3,-0.3 4,-1.1 1,-0.2 -2,-0.2 0.920 113.4 43.5 -61.5 -43.1 9.3 -23.8 -13.0 147 168 A e H X S+ 0 0 0 -4,-2.5 4,-1.8 1,-0.2 -2,-0.2 0.820 106.0 59.2 -78.0 -29.7 7.5 -21.2 -15.0 148 169 A E H < S+ 0 0 69 -4,-2.4 6,-0.3 1,-0.2 -1,-0.2 0.884 105.7 50.7 -63.7 -37.8 8.3 -22.5 -18.4 149 170 A H H < S+ 0 0 128 -4,-1.6 -1,-0.2 1,-0.2 -2,-0.2 0.849 108.1 54.5 -65.8 -32.2 6.5 -25.8 -17.4 150 171 A A H < S+ 0 0 16 -4,-1.1 -2,-0.2 1,-0.3 -1,-0.2 0.863 127.6 17.6 -69.1 -36.9 3.6 -23.6 -16.3 151 172 A Y S >< S- 0 0 22 -4,-1.8 3,-2.6 4,-0.0 4,-0.4 -0.530 91.7-148.9-134.0 67.5 3.3 -21.9 -19.7 152 173 A P T 3 S- 0 0 91 0, 0.0 -3,-0.1 0, 0.0 -4,-0.1 -0.035 76.5 -4.3 -50.3 127.4 5.2 -24.2 -22.1 153 174 A G T 3 S+ 0 0 77 -5,-0.1 -4,-0.1 2,-0.1 -5,-0.1 0.372 115.7 88.4 80.1 -5.1 6.9 -22.3 -24.9 154 175 A Q < + 0 0 112 -3,-2.6 2,-0.6 -6,-0.3 -1,-0.1 0.419 60.8 90.4-111.3 -1.0 5.4 -19.0 -23.9 155 176 A I - 0 0 17 -4,-0.4 2,-0.1 -7,-0.1 -2,-0.1 -0.880 53.4-171.3-106.4 120.7 7.9 -17.5 -21.5 156 177 A T > - 0 0 41 -2,-0.6 3,-1.5 1,-0.1 -2,-0.1 -0.459 42.5-100.4-100.4 175.6 10.7 -15.3 -22.8 157 178 A Q T 3 S+ 0 0 115 1,-0.3 54,-0.1 -2,-0.1 -1,-0.1 0.632 120.7 67.6 -69.2 -12.5 13.7 -13.9 -21.0 158 179 A N T 3 S+ 0 0 11 49,-0.1 50,-2.6 52,-0.1 2,-0.3 0.293 93.0 77.5 -89.2 9.5 11.7 -10.7 -20.8 159 180 A M E < - G 0 207B 3 -3,-1.5 2,-0.3 48,-0.3 48,-0.2 -0.924 57.5-166.8-124.9 149.6 9.3 -12.3 -18.4 160 181 A L E - G 0 206B 16 46,-3.0 46,-3.8 -2,-0.3 2,-0.4 -0.967 12.2-145.4-129.8 142.7 9.5 -13.1 -14.7 161 182 A e E +FG 142 205B 3 -19,-0.5 -19,-3.0 -2,-0.3 2,-0.3 -0.902 21.1 166.8-115.5 146.1 7.1 -15.4 -12.7 162 183 A A E +FG 141 204B 0 42,-1.9 42,-2.2 -2,-0.4 2,-0.3 -0.991 9.4 135.1-154.0 145.1 6.0 -15.0 -9.2 163 184 A G E -F 140 0B 6 -23,-2.4 -23,-2.8 -2,-0.3 2,-0.3 -0.931 43.1-108.1-171.8-169.5 3.3 -16.6 -7.0 164 185 A D > - 0 0 15 5,-0.3 4,-1.5 -2,-0.3 35,-0.2 -0.910 11.8-167.9-149.2 109.0 2.3 -18.1 -3.7 165 186 A E T 4 S+ 0 0 170 -2,-0.3 -1,-0.1 1,-0.2 35,-0.1 0.691 86.0 57.7 -75.4 -16.6 1.5 -21.8 -3.4 166 186AA K T 4 S+ 0 0 139 1,-0.1 -1,-0.2 3,-0.0 34,-0.0 0.941 130.7 0.7 -81.8 -49.3 -0.0 -21.4 0.1 167 186BA Y T 4 S- 0 0 113 2,-0.1 -2,-0.2 32,-0.0 33,-0.2 0.550 91.3-120.6-113.7 -16.6 -2.8 -19.0 -0.6 168 187 A G < - 0 0 1 -4,-1.5 31,-1.7 1,-0.2 32,-0.2 0.685 40.2-175.6 79.4 17.7 -2.5 -18.4 -4.3 169 188 A K + 0 0 42 29,-0.2 -5,-0.3 -166,-0.2 2,-0.3 -0.211 17.6 154.5 -47.6 137.1 -1.9 -14.7 -3.8 170 189 A D B -A 2 0A 1 -168,-1.3 -168,-2.0 -7,-0.1 -166,-0.2 -0.979 45.8-101.3-164.5 154.8 -1.7 -13.2 -7.3 171 190 A S - 0 0 7 -2,-0.3 27,-0.3 -170,-0.2 2,-0.2 -0.343 44.0-173.0 -78.8 173.9 -2.2 -10.0 -9.3 172 191 A f > - 0 0 13 25,-0.1 3,-2.2 -2,-0.1 4,-0.3 -0.824 35.8 -37.0-153.6-172.9 -5.4 -9.7 -11.3 173 192 A Q T 3 S+ 0 0 32 1,-0.3 -49,-2.6 -2,-0.2 -147,-0.1 -0.385 125.5 27.0 -60.5 129.5 -7.4 -7.6 -13.8 174 193 A G T 3 S+ 0 0 2 50,-2.1 -52,-0.5 -51,-0.3 -1,-0.3 0.298 99.2 89.3 98.7 -9.9 -6.7 -3.9 -13.1 175 194 A D X + 0 0 1 -3,-2.2 3,-2.2 49,-0.3 15,-0.3 0.516 55.0 137.4 -94.8 -7.4 -3.3 -4.5 -11.6 176 195 A S T 3 S+ 0 0 0 48,-0.5 -149,-2.8 -4,-0.3 15,-0.2 0.011 70.0 16.1 -42.6 138.0 -1.4 -4.2 -14.9 177 196 A G T 3 S+ 0 0 0 13,-2.8 -1,-0.3 1,-0.3 14,-0.1 0.383 92.8 136.9 80.3 -6.9 1.8 -2.2 -14.8 178 197 A G < - 0 0 0 -3,-2.2 12,-2.5 -151,-0.2 -1,-0.3 -0.322 59.6 -89.7 -70.9 158.8 1.9 -2.4 -11.0 179 198 A P E - H 0 189B 0 0, 0.0 2,-0.6 0, 0.0 -59,-0.6 -0.469 20.0-157.1 -76.1 134.4 5.3 -3.1 -9.2 180 199 A L E -EH 119 188B 0 8,-2.6 7,-2.8 -2,-0.2 8,-1.6 -0.975 27.5-161.6 -97.3 113.8 6.7 -6.5 -8.3 181 200 A V E +EH 118 186B 2 -63,-2.8 -63,-1.9 -2,-0.6 2,-0.4 -0.889 16.8 173.8-109.0 119.8 9.0 -5.3 -5.5 182 201 A d E > S-EH 117 185B 2 3,-2.2 3,-1.2 -2,-0.6 -65,-0.2 -0.987 75.2 -5.9-126.1 125.4 11.8 -7.6 -4.3 183 202 A G T 3 S- 0 0 34 -67,-0.8 -1,-0.2 -2,-0.4 3,-0.1 0.863 127.2 -64.6 59.8 32.0 14.4 -6.5 -1.8 184 203 A D T 3 S+ 0 0 120 1,-0.2 2,-0.3 -3,-0.1 -1,-0.2 0.732 115.6 108.2 63.0 23.7 12.8 -3.1 -2.0 185 208 A H E < S- H 0 182B 72 -3,-1.2 -3,-2.2 -81,-0.1 2,-0.7 -0.930 81.9 -99.1-122.5 155.2 13.8 -2.7 -5.7 186 209 A L E +cH 106 181B 0 -81,-3.2 -79,-2.7 -2,-0.3 -5,-0.2 -0.627 48.7 161.7 -74.8 115.3 11.5 -2.8 -8.7 187 210 A R E - 0 0 18 -7,-2.8 22,-1.1 -2,-0.7 23,-0.6 0.727 58.6 -5.2-106.1 -32.2 11.9 -6.3 -10.1 188 211 A G E -IH 208 180B 0 -8,-1.6 -8,-2.6 20,-0.2 2,-0.4 -0.951 54.4-125.9-154.1 172.6 8.9 -6.6 -12.4 189 212 A L E -IH 207 179B 0 18,-0.8 18,-2.5 -2,-0.3 -29,-0.2 -0.992 42.0-100.6-124.5 138.2 5.6 -5.1 -13.7 190 213 A V E +I 206 0B 5 -12,-2.5 -13,-2.8 -2,-0.4 16,-0.2 -0.352 56.5 153.5 -54.7 124.0 2.3 -6.9 -13.6 191 214 A S E - 0 0 2 14,-1.9 2,-0.3 1,-0.4 15,-0.2 0.722 52.2 -37.2-123.0 -57.5 1.8 -8.2 -17.1 192 215 A W E +I 205 0B 59 13,-2.0 13,-3.5 32,-0.1 -1,-0.4 -0.949 55.0 147.9-160.5-178.7 -0.4 -11.3 -17.3 193 216 A G - 0 0 29 -2,-0.3 11,-0.1 11,-0.2 4,-0.1 -0.979 48.9 -20.9 170.3-162.2 -1.4 -14.6 -15.6 194 217 A N - 0 0 47 8,-0.4 4,-0.2 -2,-0.3 11,-0.0 -0.344 57.2-122.5 -75.9 151.9 -4.1 -17.1 -15.0 195 218 A I S S+ 0 0 98 2,-0.1 2,-0.2 -23,-0.1 -23,-0.0 -0.962 104.4 41.5-138.3 120.6 -7.8 -16.3 -15.3 196 219 A P S S- 0 0 109 0, 0.0 2,-0.1 0, 0.0 -1,-0.0 0.518 115.5-115.8 -60.6 157.8 -9.5 -16.7 -12.9 197 220 A f + 0 0 25 -2,-0.2 2,-0.2 -72,-0.1 -2,-0.1 -0.343 64.8 107.1 -78.4 153.9 -6.7 -15.2 -10.9 198 220AA G - 0 0 15 -27,-0.3 4,-0.4 4,-0.2 3,-0.3 -0.368 50.9-140.8 140.8 133.7 -4.7 -17.1 -8.3 199 221 A S + 0 0 7 -31,-1.7 -31,-0.2 -35,-0.2 -30,-0.1 0.179 64.6 112.9-111.2 16.1 -1.2 -18.5 -8.4 200 222 A K S S+ 0 0 135 -32,-0.2 -1,-0.2 -33,-0.2 -32,-0.1 0.873 102.9 5.2 -59.2 -37.9 -1.5 -21.9 -6.7 201 223 A E S S+ 0 0 153 1,-0.3 -1,-0.1 -3,-0.3 -2,-0.1 0.720 137.2 40.0-115.2 -35.3 -0.8 -23.8 -9.9 202 224 A K S S- 0 0 63 -4,-0.4 -8,-0.4 -34,-0.1 -1,-0.3 -0.955 80.0-139.4-117.6 118.8 0.1 -21.1 -12.5 203 225 A P - 0 0 11 0, 0.0 -40,-0.2 0, 0.0 2,-0.1 -0.220 26.1-100.5 -68.7 158.8 2.2 -18.2 -11.3 204 226 A G E -G 162 0B 0 -42,-2.2 -42,-1.9 -11,-0.1 2,-0.4 -0.468 36.6-127.9 -72.8 154.0 1.6 -14.6 -12.4 205 227 A V E -GI 161 192B 0 -13,-3.5 -13,-2.0 -44,-0.2 -14,-1.9 -0.912 25.5-170.9-113.2 136.1 3.8 -13.3 -15.1 206 228 A Y E -GI 160 190B 0 -46,-3.8 -46,-3.0 -2,-0.4 2,-0.3 -0.920 31.9-103.2-128.4 143.6 5.7 -10.1 -14.8 207 229 A T E -GI 159 189B 1 -18,-2.5 2,-1.5 -2,-0.3 -18,-0.8 -0.522 39.6-121.9 -65.9 128.7 7.8 -7.9 -17.2 208 230 A N E > - I 0 188B 11 -50,-2.6 3,-1.8 -2,-0.3 4,-0.3 -0.559 31.4-173.6 -78.3 88.9 11.4 -8.6 -16.4 209 231 A V G > S+ 0 0 0 -2,-1.5 3,-2.1 -22,-1.1 -1,-0.2 0.781 74.3 68.5 -59.2 -31.6 12.5 -5.0 -15.6 210 232 A c G > S+ 0 0 7 -23,-0.6 3,-0.9 1,-0.3 -1,-0.3 0.788 93.5 61.8 -61.0 -24.1 16.2 -5.7 -15.2 211 233 A R G < S+ 0 0 102 -3,-1.8 -1,-0.3 1,-0.2 4,-0.2 0.662 101.5 52.0 -73.0 -16.6 16.3 -6.4 -18.9 212 234 A Y G <> + 0 0 7 -3,-2.1 4,-2.7 -4,-0.3 5,-0.2 0.232 69.1 112.7-112.2 13.7 15.2 -2.8 -19.7 213 235 A T H <> S+ 0 0 25 -3,-0.9 4,-2.5 1,-0.2 5,-0.2 0.911 83.5 43.1 -50.5 -51.8 17.7 -0.8 -17.8 214 236 A N H > S+ 0 0 122 -3,-0.2 4,-2.8 2,-0.2 5,-0.2 0.917 113.7 50.3 -64.3 -44.9 19.4 0.7 -20.9 215 237 A W H > S+ 0 0 41 -4,-0.2 4,-1.7 1,-0.2 -1,-0.2 0.884 112.5 48.2 -63.9 -37.2 16.2 1.3 -22.7 216 238 A I H X S+ 0 0 4 -4,-2.7 4,-2.8 2,-0.2 5,-0.3 0.950 112.4 47.6 -65.8 -48.5 14.8 3.2 -19.7 217 239 A Q H X S+ 0 0 101 -4,-2.5 4,-1.7 -5,-0.2 -2,-0.2 0.909 112.7 49.1 -60.2 -44.1 18.0 5.3 -19.2 218 240 A K H X S+ 0 0 146 -4,-2.8 4,-0.7 2,-0.2 -1,-0.2 0.862 113.5 47.2 -62.9 -36.6 18.1 6.2 -22.9 219 241 A T H >< S+ 0 0 13 -4,-1.7 3,-0.7 -5,-0.2 -2,-0.2 0.937 114.0 44.1 -74.1 -46.6 14.4 7.2 -22.9 220 242 A I H 3< S+ 0 0 38 -4,-2.8 -1,-0.2 1,-0.2 -2,-0.2 0.807 117.0 49.6 -64.1 -28.7 14.5 9.3 -19.7 221 243 A Q H 3< 0 0 134 -4,-1.7 -1,-0.2 -5,-0.3 -2,-0.2 0.584 360.0 360.0 -89.0 -11.6 17.8 10.8 -21.0 222 244 A A << 0 0 94 -3,-0.7 -3,-0.0 -4,-0.7 -4,-0.0 -0.270 360.0 360.0 -67.3 360.0 16.5 11.7 -24.5 223 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 224 301 A X 0 0 211 0, 0.0 -50,-2.1 0, 0.0 -48,-0.5 0.000 360.0 360.0 360.0 360.0 -5.3 -6.9 -18.7