==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=19-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER SIGNALLING PROTEIN 03-OCT-95 1VHH . COMPND 2 MOLECULE: SONIC HEDGEHOG; . SOURCE 2 ORGANISM_SCIENTIFIC: MUS MUSCULUS; . AUTHOR T.M.T.HALL,J.A.PORTER,P.A.BEACHY,D.J.LEAHY . 157 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 7856.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 99 63.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 4 2.5 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 23 14.6 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 11 7.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 24 15.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 26 16.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 3 1.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 2 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 39 A K 0 0 236 0, 0.0 2,-0.6 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 -93.2 29.8 -6.7 26.5 2 40 A L - 0 0 50 1,-0.0 125,-0.1 128,-0.0 124,-0.1 -0.628 360.0-164.3 -80.8 114.9 28.5 -3.5 24.9 3 41 A T - 0 0 88 -2,-0.6 -1,-0.0 123,-0.1 0, 0.0 -0.888 18.5-124.9-102.9 130.4 26.9 -1.2 27.4 4 42 A P - 0 0 70 0, 0.0 119,-0.3 0, 0.0 2,-0.2 -0.164 25.6-109.6 -64.6 159.0 24.7 1.6 26.0 5 43 A L - 0 0 5 117,-2.4 2,-0.2 116,-0.2 120,-0.1 -0.629 33.8-119.8 -86.8 155.8 25.3 5.2 26.9 6 44 A A > - 0 0 57 -2,-0.2 3,-1.9 1,-0.1 132,-0.3 -0.500 43.5 -74.4 -89.4 163.5 22.8 6.8 29.2 7 45 A Y T 3 S+ 0 0 114 1,-0.3 -1,-0.1 -2,-0.2 132,-0.1 -0.386 121.9 10.2 -58.9 132.9 20.8 9.9 28.3 8 46 A K T 3 S+ 0 0 92 130,-2.4 -1,-0.3 1,-0.3 2,-0.1 0.292 98.5 131.0 75.5 -2.8 23.1 13.0 28.4 9 47 A Q < - 0 0 73 -3,-1.9 129,-2.7 129,-0.1 2,-0.4 -0.470 39.1-163.3 -78.9 147.7 26.2 10.8 28.8 10 48 A F E -A 137 0A 59 127,-0.2 127,-0.3 -2,-0.1 -4,-0.0 -0.990 15.1-119.1-135.7 140.0 29.2 11.5 26.5 11 49 A I E S+A 136 0A 39 125,-2.8 125,-2.0 -2,-0.4 2,-0.2 -0.998 99.2 35.6-128.1 125.8 32.2 9.3 25.7 12 50 A P S S- 0 0 47 0, 0.0 2,-2.4 0, 0.0 124,-0.1 0.580 97.6-126.3 -68.9 159.6 35.0 10.1 26.3 13 51 A N S S+ 0 0 127 -2,-0.2 2,-0.3 122,-0.1 -2,-0.1 -0.242 77.7 89.8 -75.9 56.7 33.9 11.8 29.5 14 52 A V S S- 0 0 61 -2,-2.4 2,-0.0 4,-0.1 0, 0.0 -0.865 90.1 -69.3-141.8 168.5 35.5 15.2 28.6 15 53 A A > - 0 0 63 -2,-0.3 3,-1.6 1,-0.1 6,-0.2 -0.339 47.7-117.6 -62.2 146.9 34.4 18.3 26.8 16 54 A E T 3 S+ 0 0 22 1,-0.3 6,-2.6 5,-0.1 7,-0.6 0.856 108.7 50.0 -52.2 -47.1 34.0 17.8 23.0 17 55 A K T 3 S+ 0 0 59 5,-0.2 -1,-0.3 4,-0.2 2,-0.1 0.301 84.0 113.0 -80.9 6.8 36.7 20.3 21.9 18 56 A T S X >S- 0 0 45 -3,-1.6 5,-2.1 5,-0.2 3,-1.8 -0.483 80.9-112.5 -77.7 153.8 39.4 18.9 24.1 19 57 A L T 3 5S+ 0 0 107 1,-0.3 -1,-0.1 3,-0.2 130,-0.0 0.800 117.3 56.2 -56.1 -30.4 42.4 17.1 22.4 20 58 A G T 3 5S+ 0 0 63 -5,-0.1 -1,-0.3 2,-0.1 -4,-0.1 0.660 117.7 34.1 -76.9 -15.5 41.3 13.8 23.9 21 59 A A T < 5S- 0 0 0 -3,-1.8 128,-0.2 -6,-0.2 -4,-0.2 0.433 133.9 -39.7-104.3-118.2 37.9 14.1 22.3 22 60 A S T 5S- 0 0 0 -6,-2.6 128,-0.5 1,-0.2 -5,-0.2 0.480 80.3-139.4 -97.3 -0.5 37.3 15.8 18.9 23 61 A G < - 0 0 0 -5,-2.1 -1,-0.2 -7,-0.6 -5,-0.2 -0.059 44.5 -11.5 74.2-176.2 39.7 18.7 19.3 24 62 A R - 0 0 131 1,-0.1 2,-0.4 2,-0.1 126,-0.2 -0.020 62.5-112.3 -62.1 151.2 39.4 22.3 18.3 25 63 A Y - 0 0 54 1,-0.1 -1,-0.1 -8,-0.1 3,-0.1 -0.712 25.4-164.0 -80.4 128.8 36.7 23.9 16.2 26 64 A E - 0 0 82 -2,-0.4 -1,-0.1 1,-0.3 2,-0.1 0.431 48.0 -90.5 -96.6 -4.6 38.5 25.1 13.0 27 65 A G - 0 0 17 74,-0.1 -1,-0.3 73,-0.1 2,-0.1 -0.241 54.6 -49.4 113.1 158.7 35.7 27.4 11.8 28 66 A K - 0 0 100 -2,-0.1 2,-0.5 -3,-0.1 77,-0.2 -0.344 42.3-151.2 -67.8 140.4 32.6 27.3 9.7 29 67 A I - 0 0 1 75,-2.8 2,-0.3 63,-0.2 77,-0.1 -0.948 18.9-179.0-111.0 130.9 32.7 25.7 6.2 30 68 A T > - 0 0 38 -2,-0.5 3,-1.2 75,-0.1 6,-0.4 -0.892 41.4-106.7-125.8 160.1 30.2 27.2 3.8 31 69 A R T 3 S+ 0 0 96 -2,-0.3 5,-0.1 1,-0.3 -1,-0.1 0.846 122.2 46.5 -53.5 -37.6 29.5 26.3 0.1 32 70 A N T 3 S+ 0 0 151 4,-0.1 -1,-0.3 3,-0.0 -3,-0.0 0.618 97.2 102.4 -80.4 -15.4 31.1 29.5 -1.1 33 71 A S S X S- 0 0 35 -3,-1.2 3,-1.2 1,-0.1 4,-0.3 -0.247 79.5-123.4 -74.7 160.6 34.1 29.0 1.2 34 72 A E G > S+ 0 0 173 1,-0.3 3,-1.1 2,-0.1 4,-0.1 0.838 111.3 63.0 -65.5 -34.2 37.7 27.8 0.4 35 73 A R G > S+ 0 0 51 1,-0.2 3,-2.5 -7,-0.2 4,-0.3 0.618 75.2 89.9 -68.8 -13.9 37.2 25.1 3.0 36 74 A F G X S+ 0 0 59 -3,-1.2 3,-2.5 -6,-0.4 -1,-0.2 0.842 74.9 69.2 -52.8 -34.0 34.3 23.5 1.1 37 75 A K G < S+ 0 0 180 -3,-1.1 -1,-0.3 1,-0.3 -2,-0.1 0.732 86.9 69.1 -54.8 -26.6 36.9 21.3 -0.7 38 76 A E G < S+ 0 0 92 -3,-2.5 25,-0.4 -4,-0.1 2,-0.4 0.653 88.4 77.8 -68.3 -18.9 37.3 19.6 2.6 39 77 A L < - 0 0 10 -3,-2.5 23,-0.2 -4,-0.3 21,-0.1 -0.772 57.0-175.7 -99.6 140.8 33.9 18.0 2.4 40 78 A T E -F 61 0B 62 21,-2.2 21,-2.1 -2,-0.4 2,-0.1 -0.982 31.5-108.5-130.7 141.0 33.0 15.0 0.3 41 79 A P E -F 60 0B 60 0, 0.0 2,-0.6 0, 0.0 19,-0.2 -0.457 23.3-141.0 -71.1 139.8 29.5 13.5 -0.1 42 80 A N + 0 0 3 17,-1.3 18,-0.0 -2,-0.1 5,-0.0 -0.928 24.6 171.9-103.0 115.1 28.8 10.2 1.6 43 81 A Y + 0 0 162 -2,-0.6 -1,-0.1 3,-0.0 4,-0.0 0.015 15.7 156.5-112.3 29.6 26.6 8.0 -0.6 44 82 A N > - 0 0 33 1,-0.2 3,-1.4 2,-0.1 -2,-0.1 -0.329 39.0-145.9 -56.7 121.3 26.8 4.8 1.4 45 83 A P T 3 S+ 0 0 99 0, 0.0 -1,-0.2 0, 0.0 0, 0.0 0.715 95.3 64.6 -65.4 -19.0 23.7 2.8 0.5 46 84 A D T 3 S+ 0 0 60 38,-0.0 39,-0.9 2,-0.0 2,-0.4 0.227 92.2 75.0 -88.8 14.9 23.5 1.5 4.0 47 85 A I E < -b 85 0A 5 -3,-1.4 2,-0.4 37,-0.1 39,-0.2 -0.993 68.3-146.9-131.5 129.1 22.9 4.9 5.5 48 86 A I E -b 86 0A 69 37,-2.4 39,-3.0 -2,-0.4 2,-0.5 -0.791 12.2-158.7 -92.8 129.0 19.6 6.9 5.5 49 87 A F E -b 87 0A 18 -2,-0.4 39,-0.2 37,-0.2 10,-0.1 -0.964 10.0-154.8-112.2 122.4 20.0 10.7 5.3 50 88 A K - 0 0 88 37,-2.8 -1,-0.2 -2,-0.5 38,-0.1 0.916 18.4-177.4 -59.4 -45.3 17.0 12.8 6.4 51 89 A D > + 0 0 39 36,-0.3 3,-1.5 1,-0.1 5,-0.1 0.884 8.1 171.1 45.5 51.3 18.1 15.7 4.3 52 90 A E T 3 S+ 0 0 111 36,-0.3 -1,-0.1 1,-0.3 37,-0.1 0.835 74.2 54.8 -61.0 -30.4 15.2 17.8 5.6 53 91 A E T 3 S- 0 0 84 1,-0.0 -1,-0.3 0, 0.0 -2,-0.1 0.639 102.7-134.9 -75.7 -16.3 16.7 20.9 3.8 54 92 A N S < S+ 0 0 136 -3,-1.5 -2,-0.1 1,-0.1 -3,-0.1 0.915 77.6 107.2 61.0 44.6 16.7 19.1 0.5 55 93 A T S S- 0 0 67 0, 0.0 -1,-0.1 0, 0.0 -3,-0.1 0.423 87.6-119.2-125.3 -9.9 20.2 20.4 -0.2 56 94 A G S >> S+ 0 0 21 -5,-0.1 3,-1.5 3,-0.0 4,-0.5 0.450 73.5 131.4 79.1 4.4 22.2 17.2 0.3 57 95 A A G >4 + 0 0 6 1,-0.3 3,-1.2 2,-0.2 34,-0.9 0.814 58.8 67.8 -59.3 -32.4 24.1 18.9 3.1 58 96 A D G 34 S+ 0 0 6 1,-0.3 -1,-0.3 32,-0.2 31,-0.1 0.766 100.3 51.7 -58.3 -28.1 23.6 16.0 5.6 59 97 A R G <4 S+ 0 0 59 -3,-1.5 -17,-1.3 31,-0.1 2,-0.6 0.638 86.3 94.0 -83.7 -21.4 25.9 13.9 3.3 60 98 A L E << +F 41 0B 15 -3,-1.2 31,-0.5 -4,-0.5 2,-0.3 -0.704 53.6 136.7 -81.9 119.6 28.9 16.3 3.1 61 99 A M E -F 40 0B 2 -21,-2.1 -21,-2.2 -2,-0.6 46,-0.2 -0.941 54.7 -80.9-154.3 168.0 31.5 15.5 5.7 62 100 A T > - 0 0 18 44,-2.3 4,-2.8 -2,-0.3 5,-0.2 -0.321 45.7-109.2 -71.4 159.2 35.2 15.2 6.3 63 101 A Q H > S+ 0 0 105 -25,-0.4 4,-2.7 1,-0.2 5,-0.2 0.888 120.6 51.4 -56.4 -42.2 36.9 11.9 5.3 64 102 A R H > S+ 0 0 48 2,-0.2 4,-2.4 1,-0.2 -1,-0.2 0.901 109.5 50.0 -63.7 -40.9 37.4 10.9 9.0 65 103 A C H > S+ 0 0 0 1,-0.2 4,-2.7 41,-0.2 -2,-0.2 0.948 111.8 49.0 -61.9 -43.8 33.7 11.5 9.6 66 104 A K H X S+ 0 0 30 -4,-2.8 4,-2.9 1,-0.2 -2,-0.2 0.901 109.9 51.6 -60.1 -46.3 32.9 9.4 6.6 67 105 A D H X S+ 0 0 72 -4,-2.7 4,-1.8 2,-0.2 -1,-0.2 0.915 114.2 41.7 -56.8 -49.8 35.2 6.6 7.8 68 106 A K H X S+ 0 0 37 -4,-2.4 4,-2.2 2,-0.2 -2,-0.2 0.893 115.3 50.8 -67.8 -39.4 33.7 6.4 11.3 69 107 A L H X S+ 0 0 0 -4,-2.7 4,-2.3 -5,-0.2 -2,-0.2 0.919 110.1 49.9 -65.5 -41.3 30.1 6.8 9.9 70 108 A N H X S+ 0 0 42 -4,-2.9 4,-1.2 2,-0.2 -1,-0.2 0.881 110.5 49.4 -65.5 -37.5 30.7 3.9 7.4 71 109 A A H X S+ 0 0 41 -4,-1.8 4,-1.8 1,-0.2 3,-0.3 0.909 111.4 50.2 -67.6 -39.2 32.1 1.7 10.1 72 110 A L H X S+ 0 0 0 -4,-2.2 4,-2.5 1,-0.2 -2,-0.2 0.876 101.5 61.5 -66.0 -37.3 29.0 2.5 12.2 73 111 A A H X S+ 0 0 1 -4,-2.3 4,-1.4 1,-0.2 -1,-0.2 0.885 106.8 47.7 -56.9 -36.1 26.7 1.7 9.3 74 112 A I H X S+ 0 0 120 -4,-1.2 4,-1.5 -3,-0.3 -1,-0.2 0.921 111.6 47.2 -71.0 -46.9 28.1 -1.9 9.4 75 113 A S H X S+ 0 0 31 -4,-1.8 4,-2.3 2,-0.2 -2,-0.2 0.842 107.4 57.3 -67.0 -31.3 27.8 -2.3 13.2 76 114 A V H X S+ 0 0 0 -4,-2.5 4,-3.0 1,-0.2 -1,-0.2 0.952 109.2 44.2 -64.9 -47.8 24.2 -1.0 13.2 77 115 A M H < S+ 0 0 61 -4,-1.4 -1,-0.2 1,-0.2 -2,-0.2 0.801 113.4 52.8 -65.3 -31.0 23.0 -3.6 10.7 78 116 A N H < S+ 0 0 130 -4,-1.5 -1,-0.2 1,-0.1 -2,-0.2 0.879 112.7 43.6 -70.8 -37.5 25.0 -6.3 12.7 79 117 A Q H < S+ 0 0 65 -4,-2.3 -2,-0.2 1,-0.3 -3,-0.2 0.932 133.9 17.2 -72.7 -43.1 23.3 -5.3 15.9 80 118 A W S >< S- 0 0 44 -4,-3.0 3,-2.5 3,-0.2 -1,-0.3 -0.790 83.2-146.2-133.3 85.3 19.8 -5.0 14.4 81 119 A P T 3 S+ 0 0 108 0, 0.0 3,-0.1 0, 0.0 -3,-0.1 -0.243 88.2 25.8 -52.0 133.4 19.6 -6.8 11.0 82 120 A G T 3 S+ 0 0 76 1,-0.3 2,-0.4 -5,-0.1 -5,-0.1 0.289 102.7 101.4 94.8 -13.6 17.1 -4.9 8.7 83 121 A V < - 0 0 17 -3,-2.5 -1,-0.3 -7,-0.2 2,-0.3 -0.861 57.3-156.2-106.5 139.0 17.7 -1.7 10.6 84 122 A K - 0 0 57 -2,-0.4 30,-2.6 -3,-0.1 31,-0.2 -0.796 24.4-102.1-114.2 158.9 20.0 1.0 9.1 85 123 A L E -bC 47 113A 0 -39,-0.9 -37,-2.4 -2,-0.3 2,-0.4 -0.524 41.1-159.4 -72.4 144.7 22.0 3.8 10.5 86 124 A R E -bC 48 112A 28 26,-2.6 26,-2.6 -39,-0.2 2,-0.5 -0.996 11.8-152.3-135.7 130.8 20.2 7.1 9.9 87 125 A V E +bC 49 111A 0 -39,-3.0 -37,-2.8 -2,-0.4 -36,-0.3 -0.898 14.2 175.9-100.6 123.9 21.7 10.7 10.0 88 126 A T E S+ 0 0 20 22,-2.6 2,-0.3 -2,-0.5 -36,-0.3 0.601 74.3 15.0 -99.6 -19.3 19.1 13.4 10.9 89 127 A E E + C 0 110A 20 21,-1.4 21,-2.7 -31,-0.1 -1,-0.3 -0.935 65.4 147.9-157.1 131.2 21.6 16.2 10.8 90 128 A G + 0 0 0 1,-0.4 2,-0.3 -2,-0.3 -32,-0.2 0.011 64.5 14.0-127.5-122.5 25.1 16.6 9.4 91 129 A W S S- 0 0 3 -34,-0.9 2,-0.6 -31,-0.5 -1,-0.4 -0.458 73.5-146.3 -62.8 124.3 26.9 19.6 8.0 92 130 A D + 0 0 3 11,-2.0 3,-0.2 -2,-0.3 -63,-0.2 -0.850 26.8 173.4-101.7 119.2 24.8 22.6 9.0 93 131 A E S S+ 0 0 60 -2,-0.6 -1,-0.2 1,-0.1 -62,-0.0 0.643 75.7 56.3 -92.6 -18.0 24.7 25.5 6.5 94 132 A D S S- 0 0 79 0, 0.0 -1,-0.1 0, 0.0 10,-0.0 -0.106 104.4-107.7-112.3 34.4 22.0 27.4 8.5 95 133 A G + 0 0 50 -3,-0.2 4,-0.1 1,-0.2 -2,-0.0 0.817 65.1 142.5 48.4 44.9 23.2 28.1 12.1 96 134 A H + 0 0 105 2,-0.1 2,-0.3 0, 0.0 -1,-0.2 0.203 58.9 68.0 -94.2 11.9 20.9 25.6 13.9 97 135 A H S S- 0 0 44 1,-0.1 3,-0.1 4,-0.1 4,-0.1 -0.861 94.0 -80.7-129.3 167.6 23.7 24.8 16.3 98 136 A S > - 0 0 98 -2,-0.3 3,-1.5 1,-0.1 -1,-0.1 -0.114 64.9 -75.8 -61.3 160.2 25.7 26.5 19.1 99 137 A E T 3 S+ 0 0 171 1,-0.3 -1,-0.1 -4,-0.1 0, 0.0 -0.315 122.2 17.3 -55.7 138.3 28.5 28.9 18.2 100 138 A E T 3 S+ 0 0 113 1,-0.2 -1,-0.3 -3,-0.1 2,-0.2 0.708 85.8 166.9 67.6 24.9 31.5 26.8 17.2 101 139 A S X - 0 0 11 -3,-1.5 3,-1.5 1,-0.1 -1,-0.2 -0.473 42.4-133.9 -69.6 140.8 29.6 23.6 16.6 102 140 A L G > >S+ 0 0 0 1,-0.3 5,-2.5 2,-0.2 3,-1.2 0.627 102.0 75.5 -70.5 -11.4 31.5 20.9 14.7 103 141 A H G > 5S+ 0 0 1 1,-0.3 -11,-2.0 4,-0.2 3,-1.1 0.782 84.3 66.5 -67.6 -27.8 28.4 20.5 12.5 104 142 A Y G < 5S+ 0 0 9 -3,-1.5 -75,-2.8 1,-0.2 -1,-0.3 0.655 107.9 37.3 -67.6 -16.1 29.5 23.7 10.8 105 143 A E G < 5S- 0 0 3 -3,-1.2 -1,-0.2 -77,-0.2 -2,-0.2 0.083 116.9-101.9-126.3 27.0 32.5 22.0 9.4 106 144 A G T < 5S+ 0 0 2 -3,-1.1 -44,-2.3 -77,-0.1 -41,-0.2 0.791 91.3 113.8 62.3 28.7 31.2 18.6 8.5 107 145 A R < + 0 0 2 -5,-2.5 41,-2.0 -46,-0.2 2,-0.3 0.259 66.0 54.4-112.7 12.4 32.7 16.9 11.6 108 146 A A E - D 0 147A 1 -6,-0.5 2,-0.3 39,-0.2 39,-0.2 -1.000 54.1-174.3-148.4 146.0 29.5 16.0 13.4 109 147 A V E - 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