==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=15-JUL-2012 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER CHAPERONE/CHAPERONE INHIBITOR 24-AUG-11 3VHC . COMPND 2 MOLECULE: HEAT SHOCK PROTEIN HSP 90-ALPHA; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR T.A.FUKAMI,N.ONO . 216 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 11627.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 150 69.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 4 1.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 40 18.5 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 12 5.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 31 14.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 55 25.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 5 2.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 1 0 1 0 1 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 0 2 1 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 10 A Q 0 0 239 0, 0.0 3,-0.1 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 146.1 1.5 -2.6 -21.0 2 11 A P - 0 0 122 0, 0.0 2,-0.1 0, 0.0 0, 0.0 -0.323 360.0 -82.0 -63.9 145.9 4.8 -4.5 -21.7 3 12 A M - 0 0 193 1,-0.1 2,-0.2 0, 0.0 0, 0.0 -0.327 48.3-151.6 -56.7 126.2 5.7 -6.9 -18.8 4 13 A E - 0 0 159 -3,-0.1 2,-0.4 -2,-0.1 -1,-0.1 -0.634 1.9-143.2 -95.8 155.0 7.5 -5.0 -16.0 5 14 A E - 0 0 177 -2,-0.2 2,-0.4 2,-0.0 0, 0.0 -0.978 15.0-173.1-124.8 133.0 10.1 -6.6 -13.6 6 15 A E - 0 0 104 -2,-0.4 2,-0.3 158,-0.0 -2,-0.0 -0.991 21.0-128.8-127.3 137.4 10.4 -5.7 -9.9 7 16 A E - 0 0 138 -2,-0.4 158,-0.4 2,-0.0 2,-0.4 -0.652 25.3-173.0 -85.8 139.7 13.0 -6.9 -7.5 8 17 A V - 0 0 62 -2,-0.3 2,-0.5 156,-0.1 156,-0.2 -0.980 12.5-154.6-130.3 144.9 11.9 -8.5 -4.2 9 18 A E E -A 163 0A 59 154,-2.2 154,-2.3 -2,-0.4 2,-0.5 -0.985 9.9-161.2-121.5 116.0 14.0 -9.5 -1.2 10 19 A T E -A 162 0A 101 -2,-0.5 2,-0.3 152,-0.2 152,-0.2 -0.891 12.2-174.5-100.1 129.0 12.5 -12.2 1.0 11 20 A F E -A 161 0A 47 150,-3.0 150,-2.4 -2,-0.5 2,-0.4 -0.920 21.9-128.8-122.1 150.1 14.0 -12.5 4.5 12 21 A A E -A 160 0A 72 -2,-0.3 148,-0.3 148,-0.2 2,-0.2 -0.745 31.3-115.6 -93.9 139.7 13.5 -14.9 7.3 13 22 A F - 0 0 12 146,-2.1 87,-0.2 -2,-0.4 86,-0.1 -0.521 39.9 -93.8 -66.1 147.2 12.7 -13.5 10.7 14 23 A Q > - 0 0 43 85,-3.1 4,-2.4 -2,-0.2 3,-0.3 -0.304 46.4-109.4 -56.4 139.9 15.3 -14.1 13.4 15 24 A A H > S+ 0 0 65 1,-0.2 4,-1.9 2,-0.2 -1,-0.1 0.818 115.6 47.2 -51.0 -42.2 14.1 -17.3 15.2 16 25 A E H > S+ 0 0 50 2,-0.2 4,-2.6 1,-0.2 -1,-0.2 0.895 111.0 51.7 -71.2 -36.5 13.1 -15.7 18.5 17 26 A I H > S+ 0 0 0 -3,-0.3 4,-2.6 2,-0.2 -2,-0.2 0.921 109.6 50.5 -64.4 -40.6 11.2 -12.9 16.7 18 27 A A H X S+ 0 0 29 -4,-2.4 4,-2.1 2,-0.2 -2,-0.2 0.907 110.6 49.4 -62.5 -37.8 9.3 -15.5 14.7 19 28 A Q H X S+ 0 0 101 -4,-1.9 4,-2.2 2,-0.2 -2,-0.2 0.922 110.8 50.4 -64.9 -42.6 8.5 -17.3 18.0 20 29 A L H X S+ 0 0 0 -4,-2.6 4,-2.6 1,-0.2 -2,-0.2 0.904 110.0 49.8 -61.8 -45.4 7.2 -14.0 19.5 21 30 A M H X S+ 0 0 3 -4,-2.6 4,-2.4 1,-0.2 -1,-0.2 0.901 109.9 50.8 -62.7 -39.9 5.1 -13.3 16.4 22 31 A S H X S+ 0 0 64 -4,-2.1 4,-2.2 2,-0.2 -2,-0.2 0.902 111.1 49.1 -65.0 -36.4 3.5 -16.8 16.6 23 32 A L H X S+ 0 0 35 -4,-2.2 4,-1.2 1,-0.2 -2,-0.2 0.952 112.9 46.8 -64.2 -52.4 2.8 -16.3 20.3 24 33 A I H < S+ 0 0 3 -4,-2.6 -2,-0.2 1,-0.2 -1,-0.2 0.861 117.5 43.5 -57.8 -41.9 1.1 -12.9 19.7 25 34 A I H < S+ 0 0 56 -4,-2.4 -1,-0.2 1,-0.2 -2,-0.2 0.828 119.0 38.7 -73.0 -41.9 -1.0 -14.2 16.7 26 35 A N H < S+ 0 0 120 -4,-2.2 2,-0.4 -5,-0.2 -1,-0.2 0.428 102.1 77.4 -98.0 1.7 -2.2 -17.5 18.2 27 36 A T S < S- 0 0 64 -4,-1.2 2,-0.3 -3,-0.2 -4,-0.0 -0.914 77.0-121.8-115.3 137.3 -2.9 -16.5 21.8 28 37 A F + 0 0 161 -2,-0.4 2,-0.4 0, 0.0 -2,-0.1 -0.589 34.5 176.1 -74.8 133.5 -5.9 -14.6 23.1 29 38 A Y - 0 0 30 -2,-0.3 3,-0.3 105,-0.1 2,-0.1 -0.996 23.1-143.2-133.1 138.8 -5.1 -11.4 24.9 30 39 A S S S+ 0 0 74 -2,-0.4 89,-0.3 1,-0.2 0, 0.0 -0.401 85.6 48.0 -82.6 169.8 -7.3 -8.9 26.3 31 40 A N > + 0 0 46 -2,-0.1 3,-1.2 1,-0.1 -1,-0.2 0.853 60.1 154.3 67.0 37.9 -6.2 -5.3 26.0 32 41 A K T > + 0 0 27 -3,-0.3 3,-2.1 1,-0.2 4,-0.2 0.768 56.3 83.5 -67.1 -20.4 -5.2 -5.6 22.3 33 42 A E T >> + 0 0 21 1,-0.3 3,-1.6 2,-0.1 4,-0.6 0.647 67.5 81.3 -57.9 -20.2 -5.8 -1.8 22.0 34 43 A I H <> + 0 0 0 -3,-1.2 4,-2.1 1,-0.3 -1,-0.3 0.656 69.5 83.7 -64.1 -11.6 -2.2 -1.1 23.3 35 44 A F H <> S+ 0 0 0 -3,-2.1 4,-2.1 1,-0.2 -1,-0.3 0.885 88.9 51.7 -56.6 -37.7 -1.0 -1.7 19.7 36 45 A L H <> S+ 0 0 2 -3,-1.6 4,-2.8 1,-0.2 5,-0.3 0.915 105.7 53.1 -71.1 -36.7 -1.8 1.9 18.8 37 46 A R H X S+ 0 0 52 -4,-0.6 4,-2.5 1,-0.2 -1,-0.2 0.928 109.8 50.1 -59.2 -40.3 0.1 3.3 21.8 38 47 A E H X S+ 0 0 14 -4,-2.1 4,-2.1 2,-0.2 -2,-0.2 0.900 112.3 44.8 -67.6 -39.4 3.2 1.3 20.7 39 48 A L H X S+ 0 0 4 -4,-2.1 4,-2.2 2,-0.2 -1,-0.2 0.910 113.6 49.5 -72.7 -39.8 3.1 2.5 17.1 40 49 A I H X S+ 0 0 0 -4,-2.8 4,-2.7 2,-0.2 -2,-0.2 0.896 110.0 53.2 -64.2 -35.3 2.4 6.1 18.1 41 50 A S H X S+ 0 0 46 -4,-2.5 4,-2.5 -5,-0.3 -2,-0.2 0.923 108.4 48.9 -65.7 -40.5 5.4 5.8 20.6 42 51 A N H X S+ 0 0 69 -4,-2.1 4,-2.1 2,-0.2 -1,-0.2 0.897 111.8 49.6 -63.5 -40.2 7.6 4.6 17.7 43 52 A S H X S+ 0 0 4 -4,-2.2 4,-2.2 2,-0.2 -2,-0.2 0.924 110.3 50.1 -63.8 -44.0 6.5 7.5 15.6 44 53 A S H X S+ 0 0 10 -4,-2.7 4,-2.6 1,-0.2 -2,-0.2 0.918 110.2 50.3 -59.4 -41.5 7.2 10.0 18.4 45 54 A D H X S+ 0 0 85 -4,-2.5 4,-1.7 1,-0.2 -1,-0.2 0.899 111.9 47.8 -63.2 -39.7 10.7 8.5 18.9 46 55 A A H X S+ 0 0 15 -4,-2.1 41,-1.7 2,-0.2 4,-1.6 0.836 110.5 51.8 -68.9 -36.8 11.3 8.9 15.1 47 56 A L H X S+ 0 0 0 -4,-2.2 4,-2.4 39,-0.3 -2,-0.2 0.893 106.1 54.9 -68.7 -37.3 10.0 12.5 15.2 48 57 A D H X S+ 0 0 42 -4,-2.6 4,-2.7 1,-0.2 5,-0.3 0.916 105.3 53.9 -61.2 -41.9 12.4 13.3 18.1 49 58 A K H X S+ 0 0 130 -4,-1.7 4,-2.5 1,-0.2 -1,-0.2 0.927 112.1 41.7 -60.9 -47.0 15.4 12.0 15.9 50 59 A I H X S+ 0 0 0 -4,-1.6 4,-2.4 2,-0.2 -1,-0.2 0.894 113.7 54.2 -67.7 -38.4 14.6 14.3 13.0 51 60 A R H X S+ 0 0 84 -4,-2.4 4,-0.7 2,-0.2 -2,-0.2 0.946 114.9 39.0 -58.8 -53.6 13.8 17.3 15.3 52 61 A Y H >X S+ 0 0 131 -4,-2.7 3,-0.9 2,-0.2 4,-0.7 0.907 115.2 51.6 -66.1 -41.2 17.2 17.0 17.1 53 62 A E H >X S+ 0 0 73 -4,-2.5 4,-1.6 -5,-0.3 3,-0.8 0.895 107.4 55.7 -59.0 -42.1 19.2 16.2 13.9 54 63 A S H 3< S+ 0 0 17 -4,-2.4 -1,-0.2 1,-0.2 -2,-0.2 0.675 91.0 71.6 -66.8 -23.2 17.7 19.3 12.3 55 64 A L H << S+ 0 0 129 -3,-0.9 -1,-0.2 -4,-0.7 -2,-0.2 0.891 112.2 29.0 -59.5 -42.3 18.8 21.7 15.1 56 65 A T H << S+ 0 0 134 -3,-0.8 -2,-0.2 -4,-0.7 -1,-0.2 0.724 134.8 34.4 -85.6 -32.4 22.5 21.3 13.8 57 66 A D >< + 0 0 62 -4,-1.6 3,-2.4 -5,-0.2 4,-0.2 -0.696 60.4 179.7-130.2 84.9 21.5 20.7 10.2 58 67 A P G > S+ 0 0 90 0, 0.0 3,-1.9 0, 0.0 -1,-0.1 0.735 77.9 73.9 -54.7 -25.0 18.3 22.5 9.0 59 68 A S G > S+ 0 0 57 1,-0.3 3,-2.0 2,-0.2 4,-0.3 0.702 77.8 77.0 -64.7 -16.4 18.7 21.0 5.5 60 69 A K G X S+ 0 0 57 -3,-2.4 3,-0.5 1,-0.3 -1,-0.3 0.761 91.5 55.6 -64.7 -17.0 17.4 17.7 7.0 61 70 A L G X S+ 0 0 30 -3,-1.9 3,-2.3 -4,-0.2 -1,-0.3 0.361 73.2 98.8 -95.9 8.0 14.0 19.3 6.9 62 71 A D G < S+ 0 0 132 -3,-2.0 -1,-0.2 1,-0.3 3,-0.2 0.838 80.8 58.9 -63.5 -24.1 14.2 20.0 3.1 63 72 A S G < S- 0 0 34 -3,-0.5 -1,-0.3 -4,-0.3 -2,-0.1 0.374 135.1 -39.0 -82.5 3.3 12.1 16.8 2.9 64 73 A G < - 0 0 31 -3,-2.3 -1,-0.3 108,-0.1 -2,-0.1 -0.110 42.3-147.2 136.4 125.5 9.4 18.5 5.0 65 74 A K S S+ 0 0 165 -3,-0.2 2,-0.3 -2,-0.1 -3,-0.1 0.748 71.3 97.9 -81.5 -27.3 9.3 20.8 8.1 66 75 A E - 0 0 123 -5,-0.1 2,-0.6 1,-0.1 0, 0.0 -0.514 55.9-162.3 -74.1 126.6 6.1 19.6 9.6 67 76 A L + 0 0 31 -2,-0.3 2,-0.3 17,-0.1 19,-0.1 -0.936 39.2 118.7-110.5 102.4 6.6 17.0 12.4 68 77 A H - 0 0 29 -2,-0.6 17,-1.5 139,-0.2 2,-0.4 -0.955 54.1-119.1-157.4 173.4 3.4 15.2 13.0 69 78 A I E -Bc 84 209A 0 139,-2.3 141,-2.1 -2,-0.3 2,-0.4 -0.987 20.0-163.2-125.3 134.4 1.4 11.9 13.1 70 79 A N E -Bc 83 210A 29 13,-2.8 13,-2.9 -2,-0.4 2,-0.5 -0.963 5.3-155.9-118.3 138.2 -1.7 11.1 11.0 71 80 A L E -Bc 82 211A 2 139,-2.8 141,-2.8 -2,-0.4 11,-0.2 -0.960 13.5-175.7-113.1 124.7 -4.1 8.3 11.7 72 81 A I E -B 81 0A 66 9,-2.9 9,-2.0 -2,-0.5 2,-0.3 -0.825 5.9-171.2-129.0 93.6 -6.1 7.1 8.7 73 82 A P E -B 80 0A 11 0, 0.0 2,-0.5 0, 0.0 141,-0.3 -0.655 3.3-169.0 -78.9 141.2 -8.8 4.4 9.1 74 83 A N E >> -B 79 0A 54 5,-2.9 5,-1.8 -2,-0.3 4,-0.8 -0.927 10.4-175.5-133.2 104.6 -10.2 3.0 5.8 75 84 A K T 45S+ 0 0 116 -2,-0.5 -1,-0.1 3,-0.2 5,-0.0 0.786 80.8 63.3 -70.8 -27.1 -13.3 0.9 6.2 76 85 A Q T 45S+ 0 0 188 1,-0.2 -1,-0.2 3,-0.1 -2,-0.0 0.933 119.2 22.4 -64.0 -49.2 -13.4 -0.0 2.5 77 86 A D T 45S- 0 0 87 2,-0.1 -1,-0.2 -3,-0.0 -2,-0.2 0.375 106.7-121.6-101.5 7.2 -10.1 -1.9 2.5 78 87 A R T <5 + 0 0 84 -4,-0.8 103,-2.1 1,-0.2 2,-0.4 0.911 63.9 137.7 59.0 46.4 -10.1 -2.6 6.3 79 88 A T E < -BD 74 180A 7 -5,-1.8 -5,-2.9 101,-0.2 2,-0.5 -0.961 43.8-158.1-123.7 148.3 -6.8 -0.9 7.0 80 89 A L E -BD 73 179A 0 99,-1.9 99,-2.6 -2,-0.4 2,-0.4 -0.990 19.3-162.6-119.4 119.1 -5.6 1.5 9.8 81 90 A T E -BD 72 178A 16 -9,-2.0 -9,-2.9 -2,-0.5 2,-0.5 -0.891 11.1-165.4-108.8 134.2 -2.6 3.6 8.8 82 91 A I E -BD 71 177A 1 95,-2.4 95,-2.8 -2,-0.4 2,-0.4 -0.981 17.3-174.7-114.9 113.8 -0.3 5.4 11.2 83 92 A V E +BD 70 176A 25 -13,-2.9 -13,-2.8 -2,-0.5 2,-0.3 -0.937 5.5 177.7-114.9 137.5 1.9 7.9 9.3 84 93 A D E -BD 69 175A 7 91,-2.6 91,-1.0 -2,-0.4 -15,-0.2 -0.936 33.3-140.8-131.3 160.7 4.7 10.0 10.7 85 94 A T + 0 0 28 -17,-1.5 89,-0.2 -2,-0.3 -16,-0.1 -0.172 61.7 132.1-105.9 38.2 7.1 12.6 9.3 86 95 A G S S- 0 0 0 89,-0.2 -39,-0.3 -18,-0.1 -40,-0.1 0.152 78.3 -69.5 -76.2-167.8 9.9 11.2 11.5 87 96 A I - 0 0 15 -41,-1.7 59,-0.5 1,-0.1 87,-0.2 0.784 68.3-156.3 -57.4 -32.7 13.5 10.3 10.5 88 97 A G - 0 0 5 85,-0.2 2,-0.4 57,-0.1 57,-0.2 -0.081 17.2 -81.8 76.5 179.8 12.4 7.2 8.4 89 98 A M - 0 0 29 85,-0.4 56,-0.4 62,-0.1 62,-0.2 -0.974 23.9-138.0-127.7 135.2 14.6 4.2 7.6 90 99 A T > - 0 0 25 -2,-0.4 4,-2.7 54,-0.1 5,-0.2 -0.320 44.9 -96.8 -72.7 172.1 17.2 3.6 5.0 91 100 A K H > S+ 0 0 49 1,-0.2 4,-2.5 2,-0.2 5,-0.2 0.925 129.3 47.4 -56.5 -44.1 17.0 0.1 3.3 92 101 A A H > S+ 0 0 55 1,-0.2 4,-2.7 2,-0.2 -1,-0.2 0.915 111.4 49.7 -64.3 -42.2 19.7 -1.1 5.8 93 102 A D H > S+ 0 0 60 2,-0.2 4,-2.2 1,-0.2 -1,-0.2 0.883 112.2 50.3 -61.6 -39.7 17.9 0.4 8.8 94 103 A L H X S+ 0 0 0 -4,-2.7 4,-2.1 2,-0.2 -2,-0.2 0.945 113.5 41.9 -66.0 -49.9 14.6 -1.2 7.6 95 104 A I H <>S+ 0 0 23 -4,-2.5 5,-1.4 1,-0.2 6,-0.3 0.889 118.6 47.5 -65.7 -39.6 16.1 -4.8 7.2 96 105 A N H <>S+ 0 0 74 -4,-2.7 5,-0.7 -5,-0.2 3,-0.4 0.832 119.0 37.7 -68.0 -39.4 18.1 -4.4 10.5 97 106 A N H <5S+ 0 0 85 -4,-2.2 -2,-0.2 -5,-0.2 -1,-0.2 0.697 110.5 58.1 -89.1 -25.3 15.2 -3.1 12.6 98 107 A L T <5S- 0 0 14 -4,-2.1 -1,-0.2 -5,-0.2 -2,-0.1 -0.145 126.1 -45.5-107.4 39.4 12.2 -5.1 11.2 99 108 A G T 5S+ 0 0 1 -3,-0.4 -85,-3.1 2,-0.2 -82,-0.2 0.263 110.6 80.9 139.5 -25.1 13.2 -8.8 11.7 100 109 A T T - 0 0 74 1,-0.1 3,-1.1 -4,-0.1 4,-0.4 -0.815 9.2-132.4 -93.8 133.2 16.1 -8.0 19.6 104 113 A S T 3 S+ 0 0 132 -2,-0.4 4,-0.4 1,-0.2 3,-0.2 0.837 102.4 42.4 -53.4 -39.8 17.6 -7.7 23.1 105 114 A G T 3> S+ 0 0 11 20,-0.5 4,-2.4 1,-0.2 -1,-0.2 0.440 85.5 93.4 -92.1 -1.9 14.2 -8.2 24.9 106 115 A T H <> S+ 0 0 1 -3,-1.1 4,-2.4 1,-0.2 5,-0.2 0.923 87.2 45.7 -58.4 -51.8 12.6 -11.0 22.9 107 116 A K H > S+ 0 0 135 -4,-0.4 4,-2.0 -3,-0.2 -1,-0.2 0.932 116.8 43.9 -57.3 -53.3 13.8 -13.9 25.1 108 117 A A H > S+ 0 0 53 -4,-0.4 4,-2.4 1,-0.2 -1,-0.2 0.908 113.3 51.9 -63.6 -38.3 12.9 -12.3 28.4 109 118 A F H X S+ 0 0 0 -4,-2.4 4,-2.6 2,-0.2 -1,-0.2 0.911 108.9 49.5 -65.2 -41.4 9.5 -11.0 27.0 110 119 A M H X S+ 0 0 9 -4,-2.4 4,-2.6 2,-0.2 -1,-0.2 0.886 111.9 48.8 -64.4 -38.1 8.5 -14.5 25.8 111 120 A E H X S+ 0 0 129 -4,-2.0 4,-1.1 2,-0.2 -1,-0.2 0.917 111.1 49.9 -65.2 -42.8 9.4 -16.0 29.2 112 121 A A H <>S+ 0 0 27 -4,-2.4 5,-2.3 2,-0.2 3,-0.4 0.902 112.4 47.9 -60.6 -42.7 7.4 -13.3 30.9 113 122 A L H ><5S+ 0 0 15 -4,-2.6 3,-1.6 3,-0.2 -2,-0.2 0.900 108.9 53.2 -63.8 -41.8 4.5 -14.1 28.5 114 123 A Q H 3<5S+ 0 0 138 -4,-2.6 -1,-0.2 1,-0.3 -2,-0.2 0.710 107.8 52.3 -65.6 -20.6 4.9 -17.8 29.3 115 124 A A T 3<5S- 0 0 91 -4,-1.1 -1,-0.3 -3,-0.4 -2,-0.2 0.346 131.3 -96.2 -94.7 1.3 4.7 -16.8 33.1 116 125 A G T < 5 + 0 0 66 -3,-1.6 -3,-0.2 1,-0.2 -2,-0.1 0.678 62.8 167.2 92.3 25.1 1.4 -15.0 32.3 117 126 A A < - 0 0 32 -5,-2.3 -1,-0.2 -8,-0.2 2,-0.2 -0.334 43.5-102.6 -67.7 151.6 2.4 -11.3 31.8 118 127 A D > - 0 0 76 1,-0.1 3,-1.8 -89,-0.0 4,-0.1 -0.495 25.2-125.5 -70.5 139.2 -0.0 -8.8 30.2 119 128 A I G > S+ 0 0 1 -89,-0.3 3,-2.1 1,-0.3 4,-0.1 0.758 103.7 79.5 -59.1 -22.7 0.7 -8.1 26.5 120 129 A S G > S+ 0 0 29 1,-0.3 3,-0.7 2,-0.1 -1,-0.3 0.696 78.4 69.8 -58.9 -20.0 0.8 -4.4 27.5 121 130 A M G X> S+ 0 0 93 -3,-1.8 3,-0.9 1,-0.2 4,-0.8 0.567 71.6 97.3 -73.1 -10.5 4.4 -4.9 28.9 122 131 A I G X4>S+ 0 0 0 -3,-2.1 5,-1.5 1,-0.2 3,-0.6 0.774 74.3 57.1 -49.4 -40.7 5.7 -5.4 25.3 123 132 A G G X45S+ 0 0 28 -3,-0.7 3,-1.7 1,-0.2 5,-0.3 0.862 99.9 58.5 -63.1 -36.5 6.9 -1.8 24.8 124 133 A Q G <45S+ 0 0 170 -3,-0.9 -1,-0.2 1,-0.3 -2,-0.2 0.752 103.4 54.3 -64.5 -27.1 9.2 -2.0 27.9 125 134 A F G <<5S- 0 0 59 -4,-0.8 -20,-0.5 -3,-0.6 -1,-0.3 0.370 115.6-116.4 -89.0 1.2 11.0 -5.0 26.2 126 135 A G T < 5S+ 0 0 41 -3,-1.7 -3,-0.2 -22,-0.1 3,-0.1 0.586 94.2 97.1 77.5 13.6 11.6 -3.0 23.0 127 136 A V > < + 0 0 1 -5,-1.5 3,-1.6 1,-0.1 4,-0.3 0.023 37.6 128.9-119.4 23.2 9.5 -5.2 20.7 128 137 A G G > + 0 0 5 -5,-0.3 3,-2.0 -6,-0.3 4,-0.3 0.772 60.7 68.8 -53.5 -35.3 6.3 -3.0 20.8 129 138 A F G > S+ 0 0 24 1,-0.3 3,-2.4 2,-0.2 -1,-0.3 0.868 89.0 64.8 -51.9 -41.5 5.9 -2.9 17.0 130 139 A Y G X S+ 0 0 4 -3,-1.6 3,-1.9 1,-0.3 -1,-0.3 0.703 80.1 79.9 -63.8 -12.0 5.0 -6.6 17.0 131 140 A S G X S+ 0 0 0 -3,-2.0 3,-2.2 -4,-0.3 4,-0.5 0.684 72.9 81.0 -63.3 -16.5 1.8 -5.8 19.0 132 141 A A G X> S+ 0 0 0 -3,-2.4 4,-2.1 1,-0.3 3,-1.4 0.846 81.8 64.5 -55.2 -33.3 0.5 -4.8 15.6 133 142 A Y G <4 S+ 0 0 3 -3,-1.9 -1,-0.3 1,-0.3 -2,-0.2 0.528 83.8 73.8 -73.1 -3.2 -0.1 -8.6 15.0 134 143 A L G <4 S+ 0 0 2 -3,-2.2 -1,-0.3 -102,-0.1 -2,-0.2 0.832 119.4 13.8 -71.4 -32.5 -2.7 -8.6 17.9 135 144 A V T <4 S+ 0 0 0 -3,-1.4 47,-2.9 -4,-0.5 2,-0.4 0.582 119.4 70.2-116.8 -19.6 -5.1 -6.8 15.5 136 145 A A E < -E 181 0A 2 -4,-2.1 45,-0.3 45,-0.3 3,-0.1 -0.890 49.3-164.7-109.8 139.1 -3.5 -7.2 12.0 137 146 A E E S+ 0 0 108 43,-2.3 2,-0.3 -2,-0.4 44,-0.1 0.720 89.0 18.8 -83.8 -24.2 -3.2 -10.2 9.8 138 147 A K E -E 180 0A 76 42,-1.2 42,-2.8 -6,-0.1 2,-0.4 -0.989 68.4-159.6-143.9 145.2 -0.7 -8.4 7.6 139 148 A V E -EF 179 155A 0 16,-2.2 16,-2.2 -2,-0.3 2,-0.4 -0.992 2.1-166.6-128.8 133.3 1.4 -5.3 8.2 140 149 A T E -EF 178 154A 24 38,-2.2 38,-3.4 -2,-0.4 2,-0.5 -0.982 5.1-163.9-117.0 131.2 3.0 -3.1 5.5 141 150 A V E -EF 177 153A 2 12,-2.9 12,-2.9 -2,-0.4 2,-0.4 -0.980 2.9-170.0-118.3 118.4 5.7 -0.6 6.5 142 151 A I E +EF 176 152A 9 34,-2.7 34,-2.9 -2,-0.5 2,-0.4 -0.901 14.6 178.5-104.0 134.0 6.5 2.2 4.0 143 152 A T E -EF 175 151A 0 8,-2.5 8,-2.5 -2,-0.4 2,-0.4 -0.995 19.5-175.0-144.9 144.3 9.6 4.2 4.9 144 153 A K E -E 174 0A 42 30,-2.7 30,-2.8 -2,-0.4 2,-0.3 -0.961 7.0-176.5-139.9 118.6 11.6 7.1 3.4 145 154 A H > - 0 0 17 4,-0.4 3,-2.1 -56,-0.4 -57,-0.1 -0.868 38.4-115.4-111.0 149.8 14.8 8.4 4.9 146 155 A N T 3 S+ 0 0 49 -59,-0.5 -58,-0.1 -2,-0.3 -1,-0.1 0.764 114.7 52.0 -53.6 -29.9 16.7 11.5 3.5 147 156 A D T 3 S+ 0 0 135 2,-0.1 -1,-0.3 0, 0.0 2,-0.2 0.352 114.7 31.7 -91.9 1.5 19.7 9.2 2.6 148 157 A D S < S- 0 0 47 -3,-2.1 2,-0.1 -58,-0.1 -58,-0.0 -0.863 82.7 -88.8-146.9-179.1 17.8 6.5 0.7 149 158 A E - 0 0 113 -2,-0.2 -4,-0.4 1,-0.1 2,-0.3 -0.388 57.7 -79.2 -85.6 173.8 14.9 5.7 -1.6 150 159 A Q - 0 0 17 16,-0.2 16,-2.2 -6,-0.1 2,-0.3 -0.588 51.7-166.8 -78.9 129.8 11.3 4.8 -0.5 151 160 A Y E -FG 143 165A 19 -8,-2.5 -8,-2.5 -2,-0.3 2,-0.5 -0.874 14.9-147.3-121.0 150.9 11.0 1.1 0.6 152 161 A A E -FG 142 164A 11 12,-3.1 12,-1.9 -2,-0.3 2,-0.4 -0.987 13.3-174.2-120.1 121.4 8.1 -1.2 1.4 153 162 A W E +FG 141 163A 0 -12,-2.9 -12,-2.9 -2,-0.5 2,-0.3 -0.890 11.6 176.2-105.0 142.0 8.4 -3.9 4.0 154 163 A E E +FG 140 162A 49 8,-2.0 8,-2.2 -2,-0.4 2,-0.3 -0.991 10.1 172.3-147.9 149.1 5.6 -6.4 4.4 155 164 A S E -F 139 0A 0 -16,-2.2 -16,-2.2 -2,-0.3 6,-0.1 -0.963 26.9-176.3-155.7 138.9 4.7 -9.5 6.5 156 165 A S - 0 0 71 1,-0.6 2,-0.1 4,-0.4 5,-0.1 -0.081 60.2-118.3-109.4 25.2 1.8 -11.8 7.1 157 166 A A S > S+ 0 0 15 3,-0.3 3,-1.0 1,-0.1 -1,-0.6 -0.444 71.1 134.8 65.1-139.5 4.1 -13.6 9.6 158 167 A G T 3 S- 0 0 85 1,-0.2 -1,-0.1 -140,-0.1 3,-0.1 0.579 99.4 -70.1 75.4 3.5 4.7 -17.3 8.6 159 168 A G T 3 S+ 0 0 30 1,-0.2 -146,-2.1 -141,-0.1 2,-0.3 0.412 112.3 79.7 94.9 0.2 8.4 -16.6 9.4 160 169 A S E < -A 12 0A 52 -3,-1.0 -4,-0.4 -148,-0.3 -3,-0.3 -0.938 47.7-171.8-137.3 161.9 9.2 -14.4 6.5 161 170 A F E -A 11 0A 1 -150,-2.4 -150,-3.0 -2,-0.3 2,-0.3 -0.933 16.8-135.3-143.3 158.8 9.0 -10.8 5.3 162 171 A T E -AG 10 154A 14 -8,-2.2 -8,-2.0 -2,-0.3 2,-0.4 -0.916 9.0-163.9-118.4 152.2 9.7 -9.0 2.0 163 172 A V E +AG 9 153A 1 -154,-2.3 -154,-2.2 -2,-0.3 2,-0.3 -0.998 21.0 154.2-130.5 135.5 11.4 -5.7 1.2 164 173 A R E - G 0 152A 74 -12,-1.9 -12,-3.1 -2,-0.4 2,-0.2 -0.971 52.0 -85.2-150.8 163.9 11.1 -4.0 -2.2 165 174 A T E - G 0 151A 71 -158,-0.4 2,-0.4 -2,-0.3 -14,-0.3 -0.549 59.5-109.6 -69.1 131.3 11.4 -0.4 -3.7 166 175 A D - 0 0 33 -16,-2.2 -16,-0.2 -2,-0.2 -1,-0.1 -0.594 32.1-175.1 -75.9 127.9 8.0 1.1 -3.2 167 176 A T + 0 0 109 -2,-0.4 -1,-0.1 2,-0.1 2,-0.1 0.235 62.7 91.6 -97.4 2.1 5.8 1.7 -6.3 168 177 A G S S- 0 0 37 1,-0.2 -2,-0.0 0, 0.0 -16,-0.0 -0.146 97.2 -44.3 -82.2-171.0 3.2 3.4 -4.2 169 178 A E - 0 0 144 1,-0.1 -1,-0.2 -2,-0.1 -2,-0.1 -0.362 63.4-122.7 -58.7 123.7 2.9 7.2 -3.4 170 179 A P - 0 0 116 0, 0.0 2,-0.3 0, 0.0 -1,-0.1 -0.330 24.3-153.2 -64.9 147.5 6.3 8.7 -2.5 171 180 A M - 0 0 34 1,-0.1 3,-0.1 3,-0.1 -21,-0.0 -0.885 19.4-125.8-115.6 157.2 6.4 10.4 0.9 172 181 A G S S- 0 0 46 -2,-0.3 2,-0.3 1,-0.3 -1,-0.1 0.936 80.8 -35.5 -65.0 -52.0 8.8 13.2 1.7 173 182 A R S S+ 0 0 9 -89,-0.1 2,-0.3 -3,-0.1 -1,-0.3 -0.890 96.7 55.6-172.5 140.5 10.3 11.5 4.8 174 183 A G E S- E 0 144A 0 -30,-2.8 -30,-2.7 -2,-0.3 -85,-0.4 -0.879 71.0 -67.0 131.5-161.2 9.0 9.3 7.5 175 184 A T E -DE 84 143A 14 -91,-1.0 -91,-2.6 -2,-0.3 2,-0.5 -0.995 25.4-162.6-138.9 141.1 7.3 6.0 8.1 176 185 A K E -DE 83 142A 25 -34,-2.9 -34,-2.7 -2,-0.4 2,-0.6 -0.994 6.3-161.8-125.4 121.5 3.8 4.7 7.4 177 186 A V E -DE 82 141A 13 -95,-2.8 -95,-2.4 -2,-0.5 2,-0.6 -0.953 7.7-163.9-106.6 118.4 2.5 1.5 9.2 178 187 A I E -DE 81 140A 32 -38,-3.4 -38,-2.2 -2,-0.6 2,-0.7 -0.913 3.2-158.6-106.0 114.2 -0.5 0.0 7.4 179 188 A L E -DE 80 139A 0 -99,-2.6 -99,-1.9 -2,-0.6 2,-1.1 -0.877 6.3-155.4 -98.0 116.4 -2.4 -2.5 9.5 180 189 A H E -DE 79 138A 42 -42,-2.8 -43,-2.3 -2,-0.7 -42,-1.2 -0.795 33.2-136.1 -90.0 96.7 -4.5 -4.9 7.4 181 190 A L E - E 0 136A 0 -103,-2.1 -45,-0.3 -2,-1.1 5,-0.1 -0.311 4.9-113.0 -67.8 146.2 -7.0 -5.7 10.2 182 191 A K > - 0 0 53 -47,-2.9 3,-2.3 1,-0.1 -1,-0.1 -0.386 36.4-109.1 -65.4 149.9 -8.3 -9.1 11.2 183 192 A E G > S+ 0 0 134 1,-0.3 3,-0.6 2,-0.1 -1,-0.1 0.811 118.7 48.6 -55.2 -32.4 -12.1 -9.4 10.5 184 193 A D G 3 S+ 0 0 85 1,-0.2 -1,-0.3 2,-0.1 3,-0.2 0.294 101.6 65.9 -92.2 8.7 -12.9 -9.3 14.2 185 194 A Q G X + 0 0 14 -3,-2.3 3,-1.5 -50,-0.2 -1,-0.2 0.075 59.0 118.2-116.8 25.0 -10.8 -6.2 14.9 186 195 A T G X + 0 0 63 -3,-0.6 3,-2.1 1,-0.3 4,-0.2 0.597 53.1 85.2 -70.3 -9.8 -12.7 -3.6 12.9 187 196 A E G > S+ 0 0 78 1,-0.3 3,-1.9 -3,-0.2 -1,-0.3 0.820 78.7 69.1 -58.4 -28.8 -13.6 -1.5 16.0 188 197 A Y G < S+ 0 0 9 -3,-1.5 -1,-0.3 1,-0.3 -2,-0.2 0.437 90.8 60.1 -73.0 5.6 -10.1 0.1 15.4 189 198 A L G < S+ 0 0 6 -3,-2.1 2,-0.5 -116,-0.1 -1,-0.3 0.443 83.9 98.9-103.6 -3.8 -11.5 1.7 12.2 190 199 A E S <> S- 0 0 87 -3,-1.9 4,-2.3 -4,-0.2 5,-0.2 -0.716 70.4-142.8 -89.1 126.3 -14.2 3.6 14.3 191 200 A E H > S+ 0 0 67 -2,-0.5 4,-2.6 1,-0.2 5,-0.2 0.846 99.6 53.1 -58.4 -35.0 -13.3 7.2 15.1 192 201 A R H > S+ 0 0 211 2,-0.2 4,-2.4 1,-0.2 -1,-0.2 0.923 111.1 47.3 -65.5 -40.8 -14.8 7.1 18.6 193 202 A R H > S+ 0 0 44 -6,-0.3 4,-2.2 2,-0.2 -2,-0.2 0.892 112.4 49.3 -67.3 -40.9 -12.8 4.0 19.5 194 203 A I H X S+ 0 0 2 -4,-2.3 4,-2.5 1,-0.2 5,-0.2 0.937 112.0 48.4 -64.3 -43.9 -9.6 5.5 18.1 195 204 A K H X S+ 0 0 129 -4,-2.6 4,-2.5 1,-0.2 -2,-0.2 0.906 109.9 53.4 -62.6 -39.6 -10.2 8.8 20.0 196 205 A E H X S+ 0 0 106 -4,-2.4 4,-2.0 1,-0.2 -1,-0.2 0.928 112.5 43.3 -59.3 -48.2 -10.9 6.7 23.2 197 206 A I H X S+ 0 0 3 -4,-2.2 4,-2.3 2,-0.2 5,-0.4 0.853 112.7 50.9 -72.3 -31.9 -7.5 4.8 22.9 198 207 A V H X S+ 0 0 26 -4,-2.5 4,-2.4 2,-0.2 -1,-0.2 0.933 112.0 48.4 -70.6 -39.5 -5.5 7.9 22.0 199 208 A K H < S+ 0 0 137 -4,-2.5 4,-0.3 -5,-0.2 -2,-0.2 0.906 115.5 45.5 -65.2 -39.2 -6.9 9.7 25.1 200 209 A K H < S+ 0 0 134 -4,-2.0 -2,-0.2 -5,-0.2 -1,-0.2 0.886 133.3 9.6 -70.3 -41.3 -6.2 6.7 27.3 201 210 A H H < S+ 0 0 49 -4,-2.3 -3,-0.2 -5,-0.1 -2,-0.2 0.629 125.4 45.2-117.9 -20.2 -2.6 5.9 26.2 202 211 A S < + 0 0 4 -4,-2.4 3,-0.4 -5,-0.4 -3,-0.1 -0.062 65.2 113.4-128.3 39.6 -1.2 8.6 23.9 203 212 A Q S S+ 0 0 116 -4,-0.3 2,-0.9 1,-0.2 3,-0.3 0.917 79.1 46.5 -75.5 -44.8 -1.9 12.1 25.3 204 213 A F S S+ 0 0 202 1,-0.2 -1,-0.2 -3,-0.1 0, 0.0 -0.600 70.3 121.9-101.4 71.5 1.7 13.2 26.1 205 214 A I S S- 0 0 31 -2,-0.9 -1,-0.2 -3,-0.4 -2,-0.1 0.688 72.4-119.8-103.5 -22.3 3.7 12.2 23.0 206 215 A G S S+ 0 0 66 -3,-0.3 -2,-0.1 1,-0.2 -3,-0.0 0.389 81.5 71.5 101.8 1.0 5.2 15.6 21.9 207 216 A Y S S- 0 0 25 -138,-0.0 -2,-0.2 -139,-0.0 -1,-0.2 -0.977 85.5 -96.3-143.4 151.7 3.7 16.1 18.4 208 217 A P - 0 0 78 0, 0.0 -139,-2.3 0, 0.0 2,-0.4 -0.471 32.9-154.4 -72.6 140.6 0.2 16.8 17.0 209 218 A I E -c 69 0A 50 -141,-0.2 2,-0.4 -2,-0.2 -139,-0.2 -0.940 5.5-163.7-112.0 137.7 -1.9 13.9 15.9 210 219 A T E -c 70 0A 59 -141,-2.1 -139,-2.8 -2,-0.4 2,-0.5 -0.989 7.0-152.9-122.2 130.1 -4.6 14.2 13.3 211 220 A L E -c 71 0A 41 -2,-0.4 2,-0.6 -141,-0.2 -139,-0.2 -0.898 10.9-150.3 -99.2 122.9 -7.3 11.7 12.8 212 221 A F - 0 0 98 -141,-2.8 2,-0.5 -2,-0.5 -2,-0.0 -0.865 12.1-161.9 -99.2 116.9 -8.7 11.6 9.3 213 222 A V - 0 0 70 -2,-0.6 2,-0.3 -141,-0.1 -139,-0.1 -0.911 16.3-130.2-105.7 124.7 -12.4 10.5 9.2 214 223 A E - 0 0 165 -2,-0.5 -140,-0.0 -141,-0.3 -142,-0.0 -0.534 36.1-109.0 -71.1 127.6 -14.0 9.3 5.9 215 224 A K 0 0 90 -2,-0.3 -1,-0.1 1,-0.1 0, 0.0 -0.321 360.0 360.0 -63.7 139.6 -17.3 11.2 5.4 216 225 A E 0 0 154 -3,-0.0 -1,-0.1 0, 0.0 -2,-0.0 -0.082 360.0 360.0 -91.2 360.0 -20.5 9.1 5.9