==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=26-FEB-2012 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 29-NOV-11 3VL6 . COMPND 2 MOLECULE: 3-ISOPROPYLMALATE DEHYDROGENASE; . SOURCE 2 ORGANISM_SCIENTIFIC: SHEWANELLA ONEIDENSIS; . AUTHOR T.NAGAE,N.WATANABE . 364 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 15942.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 268 73.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 33 9.1 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 22 6.0 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 24 6.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 43 11.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 129 35.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 7 1.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 1 1 1 0 1 0 0 4 0 1 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 1 0 2 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 2 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A S 0 0 163 0, 0.0 2,-0.8 0, 0.0 34,-0.3 0.000 360.0 360.0 360.0-110.4 1.9 6.8 -8.7 2 2 A S - 0 0 50 32,-0.1 34,-0.2 34,-0.1 32,-0.0 -0.734 360.0-136.5 -91.4 109.5 -1.1 5.7 -6.5 3 3 A Y E -a 36 0A 50 32,-1.5 34,-2.6 -2,-0.8 2,-0.4 -0.209 8.8-148.6 -67.0 153.4 -4.4 5.6 -8.4 4 4 A Q E -a 37 0A 61 32,-0.2 63,-3.4 2,-0.0 64,-0.7 -0.993 12.3-167.3-122.9 121.8 -7.7 7.0 -7.0 5 5 A I E -ab 38 68A 3 32,-3.2 34,-2.5 -2,-0.4 2,-0.7 -0.944 15.7-146.2-115.1 128.3 -11.0 5.4 -8.0 6 6 A A E -ab 39 69A 1 62,-2.3 64,-2.1 -2,-0.4 2,-0.7 -0.846 19.5-155.0 -84.8 113.6 -14.5 6.9 -7.4 7 7 A V E +ab 40 70A 1 32,-3.2 34,-2.5 -2,-0.7 2,-0.5 -0.844 17.9 175.5 -97.7 115.2 -16.8 3.9 -6.8 8 8 A L E + b 0 71A 0 62,-3.0 64,-2.9 -2,-0.7 34,-0.1 -0.708 4.7 169.2-122.6 80.4 -20.4 4.7 -7.6 9 9 A A E - 0 0 19 -2,-0.5 64,-2.1 32,-0.3 2,-0.2 0.784 19.7-175.4 -75.2 -25.8 -22.2 1.4 -7.1 10 10 A G E - b 0 73A 8 31,-0.4 64,-0.2 62,-0.2 -1,-0.2 -0.510 32.0 -33.2 72.6-133.0 -25.7 2.9 -7.4 11 11 A D S > S+ 0 0 7 62,-3.2 3,-2.7 -2,-0.2 62,-0.3 -0.533 96.8 16.5-122.0 177.8 -28.9 0.8 -6.8 12 12 A G T 3 S- 0 0 28 1,-0.3 4,-0.3 -2,-0.2 273,-0.2 -0.341 131.8 -9.7 64.3-128.1 -30.3 -2.7 -7.2 13 13 A I T 3> S+ 0 0 22 271,-2.5 4,-2.6 1,-0.2 5,-0.4 0.544 110.1 101.6 -78.8 -11.3 -27.6 -5.2 -7.8 14 14 A G H <> S+ 0 0 0 -3,-2.7 4,-2.7 1,-0.2 5,-0.2 0.917 84.6 43.2 -41.4 -52.1 -24.9 -2.4 -8.2 15 15 A P H > S+ 0 0 65 0, 0.0 4,-2.0 0, 0.0 -1,-0.2 0.929 114.2 46.3 -67.9 -40.4 -23.5 -2.9 -4.7 16 16 A E H > S+ 0 0 36 -4,-0.3 4,-0.8 1,-0.2 -2,-0.2 0.905 118.2 43.7 -74.9 -32.5 -23.4 -6.7 -4.5 17 17 A V H >X S+ 0 0 3 -4,-2.6 4,-1.9 1,-0.2 3,-0.7 0.907 110.5 54.4 -72.7 -37.6 -21.8 -6.9 -7.9 18 18 A M H 3X S+ 0 0 4 -4,-2.7 4,-3.1 -5,-0.4 5,-0.2 0.853 100.0 62.5 -61.6 -35.8 -19.4 -4.1 -7.2 19 19 A A H 3X S+ 0 0 52 -4,-2.0 4,-1.7 1,-0.2 -1,-0.2 0.847 106.7 45.1 -54.7 -37.6 -18.3 -6.0 -4.1 20 20 A E H S+ 0 0 30 -4,-3.4 5,-2.1 2,-0.2 4,-0.8 0.929 112.9 43.2 -55.2 -45.8 -3.7 -5.2 -7.0 30 30 A A H <5S+ 0 0 85 -4,-2.0 3,-0.2 3,-0.2 -2,-0.2 0.915 115.2 48.0 -70.3 -42.7 -1.6 -7.9 -5.1 31 31 A R H <5S+ 0 0 85 -4,-2.4 -2,-0.2 1,-0.2 -1,-0.2 0.879 123.8 30.5 -65.3 -44.7 -0.5 -9.8 -8.2 32 32 A F H <5S- 0 0 51 -4,-2.7 -1,-0.2 -5,-0.2 -2,-0.2 0.424 105.0-119.9 -96.9 4.2 0.7 -6.7 -10.1 33 33 A G T <5 + 0 0 60 -4,-0.8 2,-0.4 -3,-0.2 -3,-0.2 0.953 53.1 165.5 57.0 48.7 1.7 -4.5 -7.1 34 34 A L < - 0 0 17 -5,-2.1 2,-0.8 -6,-0.3 -1,-0.2 -0.791 33.1-145.0 -96.5 143.8 -0.8 -1.8 -8.0 35 35 A N + 0 0 112 -2,-0.4 -32,-1.5 -34,-0.3 2,-0.5 -0.880 30.6 166.4-109.9 98.7 -1.7 0.9 -5.5 36 36 A I E -a 3 0A 13 -2,-0.8 2,-0.4 -34,-0.2 -32,-0.2 -0.950 17.5-164.4-117.6 126.5 -5.3 1.7 -5.9 37 37 A E E -a 4 0A 107 -34,-2.6 -32,-3.2 -2,-0.5 2,-0.4 -0.910 9.3-160.2-107.5 143.3 -7.3 3.6 -3.5 38 38 A Y E -a 5 0A 32 -2,-0.4 2,-0.4 -34,-0.2 -32,-0.2 -0.940 11.9-172.9-124.9 139.9 -11.1 3.7 -3.6 39 39 A T E -a 6 0A 65 -34,-2.5 -32,-3.2 -2,-0.4 2,-0.3 -0.998 19.2-139.5-128.3 134.1 -13.8 6.0 -2.3 40 40 A E E -a 7 0A 141 -2,-0.4 2,-0.3 -34,-0.2 -32,-0.2 -0.640 20.1-177.4 -91.7 140.4 -17.4 5.2 -2.5 41 41 A Y - 0 0 57 -34,-2.5 -31,-0.4 -2,-0.3 -32,-0.3 -0.991 30.3-109.3-138.1 145.5 -20.1 7.8 -3.3 42 42 A D + 0 0 45 -2,-0.3 2,-0.3 -34,-0.1 17,-0.1 -0.486 44.1 166.5 -69.6 141.6 -23.9 7.7 -3.5 43 43 A V > + 0 0 0 -2,-0.2 3,-0.8 12,-0.1 4,-0.5 -0.968 44.5 4.0-151.6 156.5 -25.3 7.9 -7.0 44 44 A G T 3> S- 0 0 0 10,-2.3 4,-1.7 -2,-0.3 3,-0.4 -0.369 126.6 -8.7 69.5-140.8 -28.7 7.3 -8.7 45 45 A G H 3> S+ 0 0 0 1,-0.2 4,-2.7 2,-0.2 -1,-0.2 0.828 134.5 55.1 -63.6 -36.1 -31.6 6.3 -6.3 46 46 A I H <> S+ 0 0 56 -3,-0.8 4,-2.6 1,-0.2 -1,-0.2 0.858 108.0 52.5 -69.0 -28.4 -29.5 5.8 -3.1 47 47 A A H >>S+ 0 0 0 -4,-0.5 4,-3.1 -3,-0.4 6,-0.9 0.885 107.8 50.0 -73.9 -34.5 -28.2 9.4 -3.7 48 48 A I H X5S+ 0 0 31 -4,-1.7 4,-2.0 4,-0.3 -2,-0.2 0.982 114.9 44.7 -62.8 -51.6 -31.8 10.7 -4.0 49 49 A D H <5S+ 0 0 72 -4,-2.7 -2,-0.2 1,-0.2 -1,-0.2 0.921 125.5 32.5 -52.9 -48.1 -32.7 8.9 -0.7 50 50 A N H <5S+ 0 0 87 -4,-2.6 -1,-0.2 -5,-0.1 -2,-0.2 0.657 138.8 13.3 -87.7 -25.2 -29.5 10.0 1.0 51 51 A H H <5S- 0 0 110 -4,-3.1 -3,-0.2 2,-0.2 -2,-0.2 0.374 96.6-110.5-138.8 -1.5 -28.9 13.4 -0.5 52 52 A G S < - 0 0 7 0, 0.0 4,-2.4 0, 0.0 3,-0.5 -0.177 25.6-118.4 -55.4 149.3 -24.7 14.8 -5.4 57 57 A E H > S+ 0 0 128 1,-0.2 4,-2.8 2,-0.2 5,-0.2 0.906 117.7 52.5 -48.3 -48.6 -22.1 17.7 -5.5 58 58 A A H > S+ 0 0 66 2,-0.2 4,-1.8 1,-0.2 -1,-0.2 0.836 107.8 50.3 -57.2 -39.3 -19.8 15.6 -3.3 59 59 A T H > S+ 0 0 3 -3,-0.5 4,-2.7 2,-0.2 -2,-0.2 0.962 110.9 49.1 -64.4 -53.0 -20.1 12.6 -5.7 60 60 A L H X S+ 0 0 25 -4,-2.4 4,-2.6 1,-0.2 -2,-0.2 0.954 112.2 48.2 -50.1 -52.8 -19.2 14.8 -8.7 61 61 A K H X S+ 0 0 121 -4,-2.8 4,-1.4 1,-0.2 -1,-0.2 0.851 109.2 53.8 -59.9 -35.6 -16.2 16.2 -6.8 62 62 A G H < S+ 0 0 6 -4,-1.8 4,-0.4 2,-0.2 -1,-0.2 0.911 107.9 50.1 -63.4 -42.4 -15.1 12.7 -5.8 63 63 A C H >< S+ 0 0 0 -4,-2.7 3,-1.3 1,-0.2 -2,-0.2 0.920 108.5 52.1 -61.8 -41.1 -15.2 11.8 -9.5 64 64 A E H 3< S+ 0 0 89 -4,-2.6 -1,-0.2 1,-0.3 -2,-0.2 0.818 109.4 50.7 -65.2 -28.2 -13.1 14.9 -10.4 65 65 A A T 3< S+ 0 0 77 -4,-1.4 -1,-0.3 -5,-0.2 -2,-0.2 0.514 103.4 83.8 -83.9 -3.3 -10.5 13.8 -7.7 66 66 A A S < S- 0 0 11 -3,-1.3 -61,-0.2 -4,-0.4 3,-0.1 -0.557 73.6-139.2 -98.0 159.2 -10.4 10.3 -9.2 67 67 A D S S- 0 0 64 -63,-3.4 209,-0.4 1,-0.3 2,-0.3 0.518 90.1 -6.7 -80.3 -17.1 -8.5 8.7 -12.2 68 68 A A E -b 5 0A 0 -64,-0.7 -62,-2.3 207,-0.2 2,-0.6 -0.957 66.7-117.0-167.4 159.9 -11.7 6.8 -13.2 69 69 A I E -bc 6 277A 0 207,-3.1 209,-3.1 -2,-0.3 2,-0.7 -0.939 14.8-159.7-106.5 119.2 -15.2 6.1 -12.1 70 70 A L E -bc 7 278A 0 -64,-2.1 -62,-3.0 -2,-0.6 2,-0.3 -0.861 26.7-170.6 -93.2 113.1 -16.1 2.5 -11.4 71 71 A F E -b 8 0A 1 207,-2.6 -62,-0.2 -2,-0.7 231,-0.1 -0.809 18.9-169.9-120.3 137.5 -19.9 2.7 -11.7 72 72 A G E - 0 0 1 -64,-2.9 2,-0.3 -2,-0.3 -62,-0.2 0.577 46.8 -67.0 -96.0-108.9 -22.5 0.0 -10.9 73 73 A S E -b 10 0A 7 -64,-2.1 -62,-3.2 -62,-0.3 2,-0.4 -0.996 40.3-148.2-151.1 153.7 -26.1 0.6 -12.0 74 74 A V + 0 0 12 -2,-0.3 210,-0.4 -64,-0.2 -30,-0.1 -0.922 44.8 44.4-129.9 149.3 -28.8 3.1 -11.2 75 75 A G + 0 0 1 -2,-0.4 3,-0.1 208,-0.1 -64,-0.0 -0.306 38.5 171.6 113.3 169.8 -32.6 3.1 -11.1 76 76 A G > - 0 0 12 1,-0.1 3,-1.3 -2,-0.1 4,-0.4 -0.889 53.0 -77.3 161.7 165.7 -35.5 1.0 -9.8 77 77 A P G > S+ 0 0 75 0, 0.0 3,-2.5 0, 0.0 4,-0.2 0.911 117.4 70.6 -57.2 -42.8 -39.3 1.0 -9.2 78 78 A K G 3 S+ 0 0 143 1,-0.3 3,-0.3 2,-0.1 0, 0.0 0.784 110.3 29.6 -42.2 -38.2 -38.8 3.2 -6.1 79 79 A W G X S+ 0 0 28 -3,-1.3 3,-1.6 1,-0.2 -1,-0.3 0.315 91.7 102.7-107.4 10.1 -37.8 6.3 -8.2 80 80 A E T < S+ 0 0 108 -3,-2.5 -1,-0.2 -4,-0.4 -2,-0.1 0.339 75.4 56.5 -87.5 11.5 -39.8 5.5 -11.3 81 81 A K T 3 S+ 0 0 187 -3,-0.3 -1,-0.3 -4,-0.2 -2,-0.1 0.327 82.8 114.7-111.1 3.9 -42.7 7.9 -10.5 82 82 A L S < S- 0 0 49 -3,-1.6 5,-0.1 1,-0.1 -3,-0.0 -0.439 85.1 -87.2 -71.8 147.6 -40.3 10.9 -10.3 83 83 A P >> - 0 0 73 0, 0.0 3,-2.8 0, 0.0 4,-0.7 -0.303 52.1-105.8 -53.7 141.3 -40.6 13.7 -13.0 84 84 A P T 34 S+ 0 0 85 0, 0.0 6,-0.1 0, 0.0 7,-0.1 0.549 115.8 52.2 -66.3 -6.6 -38.4 12.5 -15.8 85 85 A N T 34 S+ 0 0 118 1,-0.1 -3,-0.0 5,-0.1 0, 0.0 0.292 107.8 49.7-103.5 3.9 -35.5 14.9 -15.1 86 86 A E T <4 S+ 0 0 110 -3,-2.8 -1,-0.1 -7,-0.1 -4,-0.0 0.389 85.3 119.4-119.3 -10.0 -35.1 14.1 -11.4 87 87 A Q X - 0 0 43 -4,-0.7 4,-1.5 -5,-0.1 -43,-0.1 -0.244 69.8-121.3 -60.9 150.5 -35.0 10.4 -12.2 88 88 A P H > S+ 0 0 0 0, 0.0 4,-1.1 0, 0.0 5,-0.3 0.807 99.7 50.2 -70.6 -39.3 -31.8 8.4 -11.2 89 89 A E H >> S+ 0 0 70 2,-0.2 4,-2.5 1,-0.2 3,-1.0 0.998 120.9 31.6 -72.6 -62.7 -30.6 6.9 -14.4 90 90 A R H 3> S+ 0 0 99 1,-0.2 4,-1.5 2,-0.2 -1,-0.2 0.866 118.9 57.7 -57.9 -35.9 -30.6 10.0 -16.6 91 91 A G H 3< S+ 0 0 9 -4,-1.5 -1,-0.2 2,-0.1 -2,-0.2 0.658 116.1 33.4 -70.8 -18.9 -29.8 12.2 -13.5 92 92 A A H S+ 0 0 55 0, 0.0 4,-2.8 0, 0.0 5,-0.3 0.895 112.2 53.5 -66.2 -37.2 -24.4 14.8 -16.1 96 96 A L H X S+ 0 0 0 -4,-1.7 4,-2.3 2,-0.2 -2,-0.2 0.954 112.7 43.1 -51.8 -55.1 -21.4 12.5 -15.5 97 97 A R H X>S+ 0 0 20 -4,-2.5 5,-2.7 2,-0.2 4,-0.7 0.898 117.5 46.5 -56.3 -47.9 -20.8 12.2 -19.3 98 98 A G H <5S+ 0 0 34 -4,-2.6 3,-0.4 3,-0.2 -2,-0.2 0.919 113.4 47.4 -61.9 -48.3 -21.3 15.9 -19.9 99 99 A H H <5S+ 0 0 87 -4,-2.8 -2,-0.2 1,-0.2 -1,-0.2 0.938 120.3 36.4 -63.8 -46.3 -19.1 17.1 -17.0 100 100 A F H <5S- 0 0 20 -4,-2.3 -1,-0.2 -5,-0.3 -2,-0.2 0.486 105.8-123.8 -92.0 4.2 -16.2 14.7 -17.8 101 101 A E T <5 + 0 0 132 -4,-0.7 2,-1.9 -3,-0.4 171,-0.3 0.952 41.8 174.9 59.1 46.7 -16.6 15.0 -21.6 102 102 A L < + 0 0 0 -5,-2.7 169,-0.3 1,-0.2 -1,-0.2 -0.575 11.8 157.1 -86.6 73.3 -16.9 11.3 -21.9 103 103 A F + 0 0 9 -2,-1.9 35,-2.7 -3,-0.2 2,-0.6 0.681 49.2 73.4 -80.2 -16.5 -17.7 11.4 -25.6 104 104 A C E -DE 137 270A 2 166,-2.1 166,-3.0 33,-0.2 2,-0.5 -0.892 56.8-175.7-106.7 112.3 -16.6 7.9 -26.4 105 105 A N E -DE 136 269A 2 31,-2.6 31,-2.7 -2,-0.6 2,-0.6 -0.924 5.6-168.2-103.3 122.1 -18.8 4.9 -25.4 106 106 A L E +DE 135 268A 23 162,-3.2 162,-2.1 -2,-0.5 29,-0.2 -0.941 13.5 167.1-111.9 118.5 -17.4 1.4 -26.1 107 107 A R E -D 134 0A 23 27,-2.6 27,-2.0 -2,-0.6 2,-0.3 -0.858 13.0-169.6-131.0 91.5 -19.7 -1.6 -25.7 108 108 A P E -D 133 0A 47 0, 0.0 2,-0.5 0, 0.0 158,-0.3 -0.676 5.1-168.5 -83.5 136.3 -18.3 -4.7 -27.2 109 109 A A E +D 132 0A 2 23,-3.3 23,-2.6 -2,-0.3 2,-0.4 -0.962 10.6 168.3-127.3 120.6 -20.8 -7.6 -27.5 110 110 A K E -D 131 0A 81 -2,-0.5 2,-0.6 21,-0.2 21,-0.2 -0.964 36.2-122.3-129.2 150.5 -19.9 -11.1 -28.3 111 111 A L - 0 0 8 19,-1.5 2,-0.3 -2,-0.4 19,-0.2 -0.744 36.0-137.6 -75.7 114.9 -21.6 -14.4 -28.2 112 112 A H > - 0 0 44 -2,-0.6 3,-2.0 147,-0.2 4,-0.3 -0.642 22.9-101.2 -81.2 144.2 -19.5 -16.7 -25.9 113 113 A D T 3 S+ 0 0 142 1,-0.3 -1,-0.1 -2,-0.3 14,-0.0 -0.340 111.1 22.4 -56.0 133.1 -18.9 -20.3 -26.9 114 114 A G T 3 S+ 0 0 49 -3,-0.0 -1,-0.3 1,-0.0 3,-0.2 0.239 111.5 76.1 90.4 -14.5 -21.2 -22.6 -25.0 115 115 A L X> + 0 0 9 -3,-2.0 3,-2.2 1,-0.1 4,-0.7 0.330 56.6 106.8-111.6 5.0 -23.7 -19.8 -24.4 116 116 A E G >4 S+ 0 0 56 -4,-0.3 3,-1.1 1,-0.3 5,-0.2 0.845 71.6 64.9 -46.6 -43.1 -25.2 -19.8 -27.9 117 117 A H G 34 S+ 0 0 107 1,-0.2 -1,-0.3 -3,-0.2 -2,-0.1 0.725 97.7 56.6 -55.9 -23.5 -28.4 -21.4 -26.6 118 118 A M G <4 S+ 0 0 51 -3,-2.2 -1,-0.2 141,-0.1 -2,-0.2 0.717 82.7 99.4 -83.7 -27.1 -29.1 -18.3 -24.5 119 119 A S S << S- 0 0 8 -3,-1.1 139,-0.1 -4,-0.7 140,-0.1 -0.464 76.8-134.7 -55.9 131.9 -29.0 -15.9 -27.5 120 120 A P S S+ 0 0 86 0, 0.0 2,-0.2 0, 0.0 -1,-0.1 0.364 76.7 109.2 -69.4 0.2 -32.6 -15.0 -28.7 121 121 A L S S- 0 0 19 137,-0.4 112,-0.1 -5,-0.2 2,-0.0 -0.491 86.7 -90.9 -74.3 157.7 -31.3 -15.7 -32.2 122 122 A R >> - 0 0 159 -2,-0.2 4,-2.1 1,-0.1 3,-2.0 -0.373 46.1-107.5 -69.8 145.9 -32.3 -18.7 -34.2 123 123 A S H 3> S+ 0 0 94 1,-0.3 4,-2.2 2,-0.2 5,-0.1 0.769 117.9 50.2 -55.7 -37.3 -29.9 -21.5 -33.5 124 124 A D H 3> S+ 0 0 73 2,-0.2 4,-0.7 1,-0.2 -1,-0.3 0.758 112.2 49.8 -72.4 -21.9 -28.1 -21.5 -36.9 125 125 A I H X> S+ 0 0 12 -3,-2.0 4,-0.8 2,-0.2 3,-0.5 0.923 113.0 44.1 -76.3 -49.8 -27.6 -17.7 -36.5 126 126 A S H >< S+ 0 0 5 -4,-2.1 3,-0.7 1,-0.2 -2,-0.2 0.876 108.1 60.5 -61.6 -35.7 -26.1 -17.9 -32.9 127 127 A A H 3< S+ 0 0 74 -4,-2.2 -1,-0.2 -5,-0.3 -2,-0.2 0.813 98.5 56.1 -62.5 -34.2 -24.0 -20.9 -34.0 128 128 A R H << S- 0 0 129 -4,-0.7 -1,-0.3 -3,-0.5 -2,-0.2 0.798 104.2-157.0 -61.4 -29.2 -22.3 -18.6 -36.5 129 129 A G << - 0 0 18 -4,-0.8 2,-0.3 -3,-0.7 -1,-0.1 -0.043 8.0-139.8 77.5 173.8 -21.5 -16.4 -33.5 130 130 A F - 0 0 15 -19,-0.2 -19,-1.5 -4,-0.1 2,-0.2 -0.971 17.1-164.6-160.4 170.1 -20.7 -12.7 -33.6 131 131 A D E +D 110 0A 53 107,-0.5 2,-0.4 104,-0.4 -21,-0.2 -0.692 22.3 171.3-162.3 99.4 -18.5 -10.1 -32.0 132 132 A V E -D 109 0A 0 -23,-2.6 -23,-3.3 -2,-0.2 2,-0.6 -0.966 19.8-156.4-123.6 122.0 -19.6 -6.5 -32.5 133 133 A L E -Df 108 240A 13 106,-2.2 108,-3.7 -2,-0.4 2,-0.6 -0.932 11.2-153.5 -95.6 121.7 -18.1 -3.4 -30.9 134 134 A C E -Df 107 241A 1 -27,-2.0 -27,-2.6 -2,-0.6 2,-0.6 -0.900 6.2-165.9 -94.3 124.4 -20.5 -0.5 -30.8 135 135 A V E -Df 106 242A 0 106,-3.9 108,-3.2 -2,-0.6 2,-0.4 -0.971 15.1-173.4-107.9 113.9 -18.7 2.8 -30.7 136 136 A R E -Df 105 243A 6 -31,-2.7 -31,-2.6 -2,-0.6 2,-0.4 -0.926 27.7-125.4-122.0 131.3 -21.2 5.4 -29.7 137 137 A E E -D 104 0A 0 106,-2.7 -33,-0.2 -2,-0.4 111,-0.2 -0.656 32.7-178.8 -75.4 128.2 -20.8 9.2 -29.5 138 138 A L + 0 0 0 -35,-2.7 -35,-0.2 -2,-0.4 -34,-0.1 0.565 62.0 44.4-114.1 -15.0 -21.8 10.0 -26.0 139 139 A T S S+ 0 0 21 -36,-0.4 2,-0.1 -38,-0.1 -36,-0.1 0.409 108.0 39.1-117.4 1.0 -21.6 13.8 -25.4 140 140 A G S > S+ 0 0 5 -37,-0.2 3,-0.9 29,-0.1 4,-0.5 -0.279 75.2 63.9-123.5-147.3 -23.2 15.4 -28.4 141 141 A G G >> S- 0 0 2 23,-1.6 4,-1.2 1,-0.2 3,-0.6 -0.241 112.3 -22.8 62.4-143.9 -26.1 14.9 -30.8 142 142 A I G 34 S+ 0 0 41 1,-0.2 20,-0.3 21,-0.2 -1,-0.2 0.714 128.0 69.8 -85.1 -15.6 -29.7 15.1 -29.6 143 143 A Y G <4 S+ 0 0 46 -3,-0.9 -1,-0.2 1,-0.2 -2,-0.2 0.861 119.2 13.9 -62.4 -39.1 -28.8 14.3 -26.0 144 144 A F T <4 S+ 0 0 62 -3,-0.6 -2,-0.2 -4,-0.5 -1,-0.2 0.360 95.9 122.6-124.8 2.1 -27.1 17.6 -25.2 145 145 A G < - 0 0 7 -4,-1.2 17,-0.5 17,-0.3 18,-0.1 -0.332 56.3-111.8 -68.1 147.6 -28.1 19.7 -28.2 146 146 A K S S+ 0 0 119 15,-0.1 2,-0.2 -2,-0.0 15,-0.1 -0.945 87.3 57.4-124.2 149.8 -29.9 23.0 -27.5 147 147 A P S S+ 0 0 78 0, 0.0 2,-0.3 0, 0.0 15,-0.3 0.463 70.4 153.4 -68.9 146.9 -32.7 24.4 -27.9 148 148 A K + 0 0 80 13,-0.2 2,-0.3 -2,-0.2 13,-0.2 -0.959 31.5 62.0-139.7 135.0 -34.4 21.7 -25.8 149 149 A G E S-J 160 0B 30 11,-2.3 11,-2.6 -2,-0.3 2,-0.3 -0.996 72.9 -76.2 154.9-150.2 -37.7 22.3 -23.9 150 150 A R E -J 159 0B 174 -2,-0.3 2,-0.3 9,-0.3 9,-0.2 -0.989 25.7-170.9-150.2 158.0 -41.2 23.4 -24.6 151 151 A Q E +J 158 0B 104 7,-2.3 7,-2.8 -2,-0.3 -2,-0.0 -0.951 47.9 26.4-138.8 153.1 -43.3 26.4 -25.5 152 152 A G - 0 0 51 -2,-0.3 2,-0.3 5,-0.2 5,-0.2 -0.187 64.8-103.9 92.9-177.9 -47.1 27.0 -25.7 153 153 A E > + 0 0 163 4,-0.1 3,-1.0 -2,-0.0 4,-0.1 -0.968 67.7 3.5-148.2 158.9 -50.2 25.6 -24.1 154 154 A G G > S- 0 0 58 -2,-0.3 3,-1.6 1,-0.2 0, 0.0 -0.293 123.4 -13.3 65.4-147.1 -53.1 23.3 -25.0 155 155 A E G 3 S+ 0 0 198 1,-0.3 -1,-0.2 3,-0.0 -3,-0.0 0.762 140.4 50.5 -58.3 -31.1 -53.1 21.6 -28.4 156 156 A S G < S+ 0 0 94 -3,-1.0 -1,-0.3 2,-0.1 -2,-0.2 0.356 77.6 121.5 -95.4 7.6 -50.4 23.9 -29.8 157 157 A E < - 0 0 83 -3,-1.6 2,-0.3 -5,-0.2 -5,-0.2 -0.512 45.3-175.5 -62.6 133.1 -48.0 23.3 -26.9 158 158 A E E -J 151 0B 113 -7,-2.8 -7,-2.3 -2,-0.2 2,-0.3 -0.962 20.2-155.5-137.1 155.3 -44.9 21.8 -28.4 159 159 A A E -J 150 0B 65 -2,-0.3 2,-0.3 -9,-0.2 -9,-0.3 -0.873 15.3-169.1-125.4 161.0 -41.7 20.4 -27.2 160 160 A F E -J 149 0B 61 -11,-2.6 -11,-2.3 -2,-0.3 2,-0.3 -0.983 16.1-170.9-155.9 148.5 -38.3 20.2 -29.0 161 161 A D - 0 0 84 -2,-0.3 2,-0.5 -13,-0.2 -13,-0.2 -0.960 21.3-138.0-139.7 146.3 -34.8 18.7 -28.9 162 162 A T - 0 0 32 -17,-0.5 2,-0.6 -2,-0.3 -17,-0.3 -0.955 2.6-153.7-113.5 120.3 -32.0 19.6 -31.3 163 163 A M + 0 0 40 -2,-0.5 2,-0.4 -19,-0.1 -21,-0.2 -0.818 30.0 172.3 -85.9 122.8 -29.7 17.0 -32.7 164 164 A R + 0 0 141 -2,-0.6 -23,-1.6 -23,-0.2 2,-0.3 -0.999 12.6 172.6-138.5 129.1 -26.5 18.9 -33.4 165 165 A Y - 0 0 19 -2,-0.4 2,-0.2 -25,-0.1 37,-0.1 -0.984 14.2-155.6-134.7 141.1 -23.0 17.6 -34.5 166 166 A S > - 0 0 42 -2,-0.3 4,-1.9 1,-0.1 3,-0.3 -0.679 34.8-109.5-100.3 163.8 -19.8 19.5 -35.5 167 167 A R H > S+ 0 0 110 1,-0.2 4,-2.8 -2,-0.2 5,-0.2 0.877 119.4 55.3 -57.4 -39.9 -17.1 18.0 -37.8 168 168 A R H > S+ 0 0 182 1,-0.2 4,-1.8 2,-0.2 -1,-0.2 0.852 106.7 48.0 -65.1 -40.8 -14.8 17.9 -34.7 169 169 A E H > S+ 0 0 40 -3,-0.3 4,-1.5 2,-0.2 -1,-0.2 0.890 115.3 45.2 -67.7 -41.3 -17.2 15.9 -32.6 170 170 A I H X S+ 0 0 0 -4,-1.9 4,-2.4 1,-0.2 -2,-0.2 0.893 110.9 51.9 -69.2 -46.4 -17.8 13.4 -35.4 171 171 A S H X S+ 0 0 11 -4,-2.8 4,-2.4 1,-0.2 5,-0.2 0.866 107.7 51.5 -62.3 -42.5 -14.1 13.0 -36.4 172 172 A R H X S+ 0 0 72 -4,-1.8 4,-1.3 2,-0.2 -1,-0.2 0.900 114.2 42.7 -65.4 -36.6 -13.0 12.2 -32.8 173 173 A I H X S+ 0 0 0 -4,-1.5 4,-2.1 2,-0.2 -2,-0.2 0.885 114.2 53.4 -71.5 -33.1 -15.6 9.4 -32.3 174 174 A A H X S+ 0 0 0 -4,-2.4 4,-2.8 1,-0.2 5,-0.2 0.927 104.9 52.7 -68.5 -42.2 -14.9 8.1 -35.8 175 175 A R H X S+ 0 0 99 -4,-2.4 4,-2.8 1,-0.2 5,-0.3 0.919 107.5 54.0 -58.6 -40.4 -11.1 7.9 -35.2 176 176 A I H X S+ 0 0 37 -4,-1.3 4,-2.2 1,-0.2 -1,-0.2 0.945 109.7 46.6 -59.2 -43.2 -11.9 5.8 -32.1 177 177 A A H X S+ 0 0 0 -4,-2.1 4,-2.7 2,-0.2 -2,-0.2 0.917 114.4 46.2 -66.2 -45.3 -14.0 3.4 -34.2 178 178 A F H X S+ 0 0 0 -4,-2.8 4,-2.3 2,-0.2 -1,-0.2 0.892 112.2 50.0 -63.2 -43.9 -11.4 3.1 -37.0 179 179 A E H X S+ 0 0 108 -4,-2.8 4,-1.2 -5,-0.2 -1,-0.2 0.910 112.4 48.6 -59.6 -41.2 -8.6 2.6 -34.5 180 180 A A H >< S+ 0 0 26 -4,-2.2 3,-0.5 -5,-0.3 -2,-0.2 0.939 111.9 48.4 -66.7 -48.0 -10.7 -0.1 -32.8 181 181 A A H ><>S+ 0 0 0 -4,-2.7 5,-3.0 1,-0.2 3,-2.4 0.880 102.8 63.7 -53.9 -41.9 -11.5 -1.8 -36.1 182 182 A R H 3<5S+ 0 0 102 -4,-2.3 -1,-0.2 1,-0.3 -2,-0.2 0.862 108.7 40.0 -54.4 -38.9 -7.8 -1.7 -37.0 183 183 A G T <<5S+ 0 0 71 -4,-1.2 -1,-0.3 -3,-0.5 -2,-0.2 0.229 124.1 40.6 -95.5 13.5 -7.1 -4.0 -34.1 184 184 A R T < 5S- 0 0 73 -3,-2.4 -3,-0.1 -5,-0.1 -2,-0.1 0.228 130.8 -39.9-120.6-113.3 -10.2 -6.2 -34.7 185 185 A R T 5S- 0 0 126 2,-0.2 -3,-0.2 -2,-0.0 -4,-0.1 0.151 76.6-115.1-110.7 18.3 -11.4 -7.3 -38.1 186 186 A K S > + 0 0 41 30,-0.2 4,-2.8 -2,-0.2 3,-2.0 -0.456 47.3 155.1-140.1 60.7 -30.0 8.3 -41.1 194 194 A A T 34 + 0 0 17 6,-0.3 7,-0.1 1,-0.3 29,-0.0 0.683 66.0 67.7 -69.4 -15.3 -28.3 10.5 -43.8 195 195 A N T 34 S+ 0 0 85 1,-0.1 -1,-0.3 5,-0.1 3,-0.1 0.597 120.8 16.0 -76.6 -6.2 -31.4 10.1 -46.1 196 196 A V T <4 S+ 0 0 100 -3,-2.0 2,-0.5 1,-0.2 -2,-0.2 0.635 112.5 67.7-134.0 -35.4 -33.3 12.3 -43.5 197 197 A L X - 0 0 52 -4,-2.8 4,-1.8 1,-0.1 -1,-0.2 -0.860 54.4-152.2-113.9 131.1 -31.1 14.1 -41.1 198 198 A A H > S+ 0 0 85 -2,-0.5 4,-2.2 2,-0.2 5,-0.3 0.874 104.0 56.3 -56.5 -42.7 -28.7 17.0 -41.7 199 199 A C H > S+ 0 0 20 1,-0.2 4,-2.3 2,-0.2 -1,-0.2 0.885 109.0 48.6 -55.4 -39.5 -26.7 15.8 -38.7 200 200 A S H > S+ 0 0 3 -7,-0.3 4,-3.0 2,-0.2 -6,-0.3 0.814 105.3 56.0 -72.7 -34.7 -26.4 12.4 -40.5 201 201 A V H X S+ 0 0 80 -4,-1.8 4,-2.0 -8,-0.2 -2,-0.2 0.960 114.6 39.5 -55.6 -51.2 -25.4 14.0 -43.8 202 202 A L H X S+ 0 0 43 -4,-2.2 4,-3.6 2,-0.2 5,-0.3 0.911 113.3 57.7 -66.9 -38.8 -22.4 15.7 -42.0 203 203 A W H X S+ 0 0 3 -4,-2.3 4,-2.2 -5,-0.3 5,-0.3 0.964 110.4 41.8 -52.4 -53.5 -21.9 12.5 -39.9 204 204 A R H X S+ 0 0 61 -4,-3.0 4,-1.8 1,-0.2 -1,-0.2 0.859 114.9 52.3 -65.2 -37.2 -21.5 10.4 -43.0 205 205 A Q H X S+ 0 0 97 -4,-2.0 4,-1.2 -5,-0.2 -1,-0.2 0.963 112.7 43.3 -67.0 -48.9 -19.4 13.0 -44.7 206 206 A V H X S+ 0 0 0 -4,-3.6 4,-2.4 2,-0.2 -1,-0.2 0.831 108.8 54.7 -64.2 -36.0 -17.0 13.3 -41.9 207 207 A V H X S+ 0 0 0 -4,-2.2 4,-1.8 -5,-0.3 -1,-0.2 0.903 108.6 52.0 -73.7 -35.5 -16.5 9.7 -41.1 208 208 A E H < S+ 0 0 99 -4,-1.8 4,-0.5 -5,-0.3 -1,-0.3 0.836 106.9 52.6 -60.0 -34.9 -15.6 9.3 -44.7 209 209 A E H >< S+ 0 0 79 -4,-1.2 3,-1.2 1,-0.2 4,-0.3 0.931 109.3 49.3 -67.7 -40.8 -13.0 12.1 -44.3 210 210 A V H >< S+ 0 0 5 -4,-2.4 3,-1.9 1,-0.2 4,-0.2 0.888 96.5 72.9 -65.8 -34.1 -11.5 10.2 -41.2 211 211 A A G >< S+ 0 0 19 -4,-1.8 3,-2.1 1,-0.3 6,-0.2 0.700 79.9 72.9 -55.2 -26.8 -11.4 7.0 -43.3 212 212 A V G < S+ 0 0 115 -3,-1.2 -1,-0.3 -4,-0.5 -2,-0.2 0.810 93.8 55.0 -59.4 -32.3 -8.3 8.4 -45.4 213 213 A D G < S+ 0 0 99 -3,-1.9 -1,-0.3 -4,-0.3 -2,-0.2 0.443 107.5 52.3 -78.2 -4.5 -6.2 7.8 -42.3 214 214 A F X + 0 0 7 -3,-2.1 3,-2.1 -4,-0.2 -1,-0.2 -0.531 57.2 156.8-131.2 69.5 -7.2 4.2 -42.2 215 215 A P T 3 S+ 0 0 118 0, 0.0 -1,-0.1 0, 0.0 -2,-0.1 0.759 76.6 58.5 -74.5 -18.4 -6.6 2.7 -45.6 216 216 A D T 3 S+ 0 0 55 -3,-0.1 2,-0.5 2,-0.1 -2,-0.0 0.459 95.4 79.7 -77.8 -2.8 -6.4 -0.8 -44.1 217 217 A V S < S- 0 0 12 -3,-2.1 2,-0.4 -6,-0.2 -30,-0.2 -0.925 75.1-137.1-114.5 130.0 -10.0 -0.5 -42.6 218 218 A E E -g 187 0A 116 -32,-3.0 -30,-3.2 -2,-0.5 2,-0.5 -0.668 19.2-161.7 -81.5 133.3 -13.1 -1.0 -44.7 219 219 A L E +g 188 0A 30 -2,-0.4 2,-0.3 -32,-0.2 -30,-0.2 -0.957 14.3 169.7-111.6 129.9 -15.9 1.6 -44.1 220 220 A E E -g 189 0A 57 -32,-2.7 -30,-2.8 -2,-0.5 2,-0.4 -0.937 22.1-139.9-125.9 160.9 -19.5 1.1 -45.0 221 221 A H E +g 190 0A 44 -2,-0.3 2,-0.3 -32,-0.2 -30,-0.2 -0.914 20.1 177.6-116.2 154.5 -22.5 3.2 -44.1 222 222 A I E -g 191 0A 12 -32,-2.4 -30,-2.4 -2,-0.4 2,-0.2 -0.970 30.8-114.0-149.1 147.8 -25.9 1.9 -43.1 223 223 A Y E > -g 192 0A 75 -2,-0.3 4,-2.5 -32,-0.2 -30,-0.2 -0.649 31.7-117.0 -83.8 153.4 -29.1 3.6 -42.0 224 224 A I H > S+ 0 0 17 -32,-2.5 4,-2.3 -2,-0.2 5,-0.1 0.787 113.8 53.0 -61.1 -37.0 -30.2 2.9 -38.5 225 225 A D H > S+ 0 0 86 2,-0.2 4,-1.6 1,-0.2 -1,-0.2 0.919 114.5 44.7 -68.0 -35.9 -33.5 1.1 -39.4 226 226 A N H > S+ 0 0 60 2,-0.2 4,-2.9 1,-0.2 -2,-0.2 0.920 111.0 53.5 -71.3 -38.0 -31.5 -1.1 -41.7 227 227 A A H X S+ 0 0 0 -4,-2.5 4,-2.1 1,-0.2 -2,-0.2 0.897 107.3 51.3 -65.0 -40.0 -28.8 -1.7 -39.0 228 228 A T H X S+ 0 0 40 -4,-2.3 4,-0.9 1,-0.2 -1,-0.2 0.918 113.8 44.0 -68.7 -32.5 -31.3 -2.8 -36.6 229 229 A M H X S+ 0 0 114 -4,-1.6 4,-0.9 1,-0.2 3,-0.4 0.933 113.8 49.5 -68.6 -48.2 -32.8 -5.3 -39.0 230 230 A Q H X S+ 0 0 32 -4,-2.9 4,-3.0 1,-0.2 3,-0.3 0.796 105.6 56.4 -65.7 -32.4 -29.4 -6.6 -40.2 231 231 A L H < S+ 0 0 0 -4,-2.1 -1,-0.2 1,-0.2 -2,-0.2 0.822 104.8 52.8 -68.5 -34.5 -28.1 -7.1 -36.7 232 232 A L H < S+ 0 0 86 -4,-0.9 -1,-0.2 -3,-0.4 -2,-0.2 0.747 121.9 32.3 -61.5 -30.6 -31.1 -9.5 -35.9 233 233 A R H < S+ 0 0 144 -4,-0.9 -2,-0.2 -3,-0.3 -3,-0.1 0.806 136.9 8.7-106.1 -43.0 -30.3 -11.5 -39.0 234 234 A R >< + 0 0 29 -4,-3.0 3,-1.7 -5,-0.1 -2,-0.1 -0.447 61.9 156.5-140.3 65.5 -26.6 -11.6 -39.7 235 235 A P G > + 0 0 0 0, 0.0 3,-1.3 0, 0.0 -104,-0.4 0.688 69.3 74.4 -63.6 -17.7 -24.8 -9.9 -36.7 236 236 A D G 3 S+ 0 0 45 1,-0.2 -106,-0.1 -106,-0.2 -5,-0.1 0.709 83.7 68.1 -67.4 -17.6 -21.7 -11.9 -37.7 237 237 A E G < S+ 0 0 89 -3,-1.7 2,-0.4 -7,-0.2 -1,-0.2 0.543 87.3 80.5 -83.7 0.2 -21.2 -9.5 -40.6 238 238 A F < + 0 0 0 -3,-1.3 -107,-0.5 1,-0.2 3,-0.1 -0.844 41.3 167.9-107.9 146.3 -20.3 -6.5 -38.4 239 239 A D S S+ 0 0 0 -2,-0.4 -106,-2.2 1,-0.3 2,-0.5 0.675 74.2 7.1-110.1 -80.4 -17.1 -5.7 -36.8 240 240 A V E -fh 133 188A 0 -53,-2.1 -51,-3.7 -108,-0.2 2,-0.6 -0.941 64.7-158.2-107.2 126.1 -17.2 -2.1 -35.4 241 241 A M E -fh 134 189A 1 -108,-3.7 -106,-3.9 -2,-0.5 2,-0.6 -0.908 7.2-160.3-106.1 125.4 -20.4 -0.2 -35.4 242 242 A L E +fh 135 190A 0 -53,-2.9 -51,-3.0 -2,-0.6 2,-0.3 -0.931 21.1 165.8-113.3 115.0 -19.9 3.6 -35.3 243 243 A C E -fh 136 191A 0 -108,-3.2 -106,-2.7 -2,-0.6 -51,-0.1 -0.903 35.7-117.1-134.5 155.3 -22.9 5.6 -34.1 244 244 A S > - 0 0 6 -53,-0.6 4,-2.4 -2,-0.3 5,-0.3 -0.132 55.2 -83.7 -72.5-177.0 -24.1 9.0 -32.9 245 245 A N H > S+ 0 0 1 2,-0.2 4,-1.7 1,-0.2 5,-0.1 0.931 123.5 36.5 -64.4 -55.0 -25.7 9.3 -29.5 246 246 A L H > S+ 0 0 59 1,-0.2 4,-1.9 2,-0.2 -1,-0.2 0.969 121.8 45.1 -65.9 -49.8 -29.3 8.3 -30.0 247 247 A F H > S+ 0 0 17 1,-0.2 4,-2.7 2,-0.2 -1,-0.2 0.849 112.5 50.6 -58.5 -41.8 -28.6 5.6 -32.6 248 248 A G H X S+ 0 0 0 -4,-2.4 4,-2.6 1,-0.2 5,-0.3 0.824 106.0 57.5 -69.3 -32.0 -25.7 4.1 -30.6 249 249 A D H X S+ 0 0 45 -4,-1.7 4,-1.3 -5,-0.3 -1,-0.2 0.933 112.2 40.0 -61.9 -46.9 -27.9 3.9 -27.7 250 250 A I H X S+ 0 0 80 -4,-1.9 4,-2.0 1,-0.2 -2,-0.2 0.942 118.9 46.1 -68.0 -43.6 -30.4 1.8 -29.6 251 251 A L H X S+ 0 0 2 -4,-2.7 4,-2.4 1,-0.2 5,-0.3 0.878 108.3 53.1 -75.0 -38.5 -27.8 -0.3 -31.4 252 252 A S H X S+ 0 0 2 -4,-2.6 4,-1.7 1,-0.2 -1,-0.2 0.899 112.3 45.0 -66.5 -42.0 -25.6 -1.1 -28.4 253 253 A D H X S+ 0 0 68 -4,-1.3 4,-2.3 -5,-0.3 -1,-0.2 0.851 111.0 56.4 -65.3 -38.6 -28.5 -2.4 -26.4 254 254 A E H X S+ 0 0 33 -4,-2.0 4,-2.0 2,-0.2 -2,-0.2 0.964 111.4 39.3 -60.1 -51.3 -29.8 -4.4 -29.4 255 255 A I H X S+ 0 0 2 -4,-2.4 4,-1.0 2,-0.2 -1,-0.2 0.859 112.7 58.3 -72.9 -25.8 -26.6 -6.4 -30.0 256 256 A A H >X S+ 0 0 2 -4,-1.7 3,-0.6 -5,-0.3 4,-0.5 0.945 109.4 43.4 -63.2 -45.0 -26.1 -6.8 -26.3 257 257 A M H >< S+ 0 0 112 -4,-2.3 3,-1.5 1,-0.2 -1,-0.2 0.867 105.9 63.6 -65.8 -36.3 -29.5 -8.5 -26.0 258 258 A L H 3< S+ 0 0 11 -4,-2.0 -137,-0.4 1,-0.3 -1,-0.2 0.768 94.3 62.8 -59.8 -24.4 -28.7 -10.5 -29.2 259 259 A T H << S- 0 0 1 -4,-1.0 -1,-0.3 -3,-0.6 -147,-0.2 0.834 97.3-143.4 -70.5 -25.8 -25.9 -12.1 -27.2 260 260 A G S << S+ 0 0 23 -3,-1.5 2,-0.1 -4,-0.5 -3,-0.1 0.229 81.6 81.5 82.9 -12.0 -28.4 -13.5 -24.8 261 261 A S > + 0 0 4 -5,-0.5 3,-1.8 1,-0.1 4,-0.2 -0.433 41.4 155.0-131.1 65.3 -25.9 -12.8 -22.0 262 262 A M G > + 0 0 37 1,-0.3 3,-2.4 2,-0.2 19,-0.4 0.793 68.3 72.1 -61.7 -33.8 -25.9 -9.2 -20.9 263 263 A G G 3 S+ 0 0 19 1,-0.3 35,-1.5 18,-0.1 -1,-0.3 0.467 98.6 52.5 -64.1 -1.1 -24.5 -10.1 -17.4 264 264 A L G < S+ 0 0 4 -3,-1.8 2,-0.4 33,-0.2 -1,-0.3 0.439 93.2 88.4-104.5 -5.6 -21.2 -10.7 -19.2 265 265 A L < - 0 0 8 -3,-2.4 16,-2.5 -4,-0.2 17,-0.4 -0.776 52.9-173.6-106.7 140.3 -20.9 -7.4 -21.1 266 266 A S E - I 0 280A 11 -2,-0.4 2,-0.4 -158,-0.3 33,-0.1 -0.722 12.0-136.3-125.6-179.7 -19.4 -4.2 -19.8 267 267 A S E - I 0 279A 2 12,-2.5 12,-1.8 -2,-0.2 2,-0.4 -0.981 4.8-160.3-139.6 139.6 -19.1 -0.6 -21.0 268 268 A A E -EI 106 278A 0 -162,-2.1 -162,-3.2 -2,-0.4 2,-0.5 -0.992 6.6-175.7-119.2 127.8 -16.3 2.1 -21.2 269 269 A S E +EI 105 277A 1 8,-2.0 8,-2.9 -2,-0.4 2,-0.4 -0.978 23.2 174.3-118.0 113.4 -17.3 5.8 -21.5 270 270 A M E -EI 104 276A 19 -166,-3.0 -166,-2.1 -2,-0.5 6,-0.2 -0.901 28.8-145.6-131.4 152.2 -14.1 7.8 -21.9 271 271 A N > - 0 0 25 4,-2.5 3,-1.2 -2,-0.4 -169,-0.1 -0.429 45.7 -91.9 -96.7-178.1 -12.8 11.3 -22.6 272 272 A S T 3 S+ 0 0 103 -171,-0.3 -170,-0.1 1,-0.3 -171,-0.1 0.638 119.0 58.7 -76.6 -15.3 -9.7 12.1 -24.5 273 273 A T T 3 S- 0 0 119 2,-0.1 -1,-0.3 0, 0.0 3,-0.1 0.210 118.5 -99.8 -94.5 9.9 -7.3 12.2 -21.5 274 274 A G S < S+ 0 0 16 -3,-1.2 2,-0.3 1,-0.4 38,-0.1 0.431 80.9 130.3 90.5 -7.0 -8.0 8.7 -20.3 275 275 A F + 0 0 24 -175,-0.1 -4,-2.5 -207,-0.1 -1,-0.4 -0.644 35.3 162.4 -72.5 141.0 -10.4 9.4 -17.6 276 276 A G E - I 0 270A 0 -209,-0.4 -207,-3.1 -2,-0.3 2,-0.5 -0.986 43.2-120.6-157.3 176.3 -13.5 7.3 -17.9 277 277 A L E -cI 69 269A 1 -8,-2.9 -8,-2.0 -2,-0.3 2,-0.5 -0.973 29.3-163.1-121.9 122.4 -16.6 5.8 -16.5 278 278 A F E +cI 70 268A 0 -209,-3.1 -207,-2.6 -2,-0.5 -10,-0.2 -0.928 20.5 151.4-120.8 126.7 -16.8 2.0 -16.5 279 279 A E E - I 0 267A 19 -12,-1.8 -12,-2.5 -2,-0.5 -207,-0.1 -0.953 46.3 -90.3-152.0 159.5 -20.0 0.0 -16.0 280 280 A P E - I 0 266A 18 0, 0.0 -14,-0.3 0, 0.0 -17,-0.1 -0.409 34.9-128.8 -70.6 148.7 -22.0 -3.2 -16.7 281 281 A A S S+ 0 0 14 -16,-2.5 -15,-0.1 -19,-0.4 -18,-0.1 0.805 86.2 70.9 -69.4 -26.2 -24.1 -3.0 -19.8 282 282 A G S S- 0 0 28 -17,-0.4 -29,-0.0 -20,-0.3 -26,-0.0 -0.325 86.1-101.3 -89.2 169.8 -27.3 -4.2 -18.1 283 283 A G - 0 0 59 -210,-0.1 -1,-0.2 1,-0.1 -208,-0.1 0.150 44.8 -81.4 -77.7-159.8 -29.5 -2.3 -15.5 284 284 A S - 0 0 9 -210,-0.4 -271,-2.5 -272,-0.1 -270,-0.2 0.418 49.2-148.3 -88.6 -0.7 -29.8 -2.4 -11.7 285 285 A A > - 0 0 31 -273,-0.2 3,-2.0 1,-0.1 4,-0.2 0.796 18.2-173.4 35.8 57.8 -32.1 -5.5 -12.0 286 286 A P G > S+ 0 0 59 0, 0.0 3,-1.4 0, 0.0 -1,-0.1 0.768 72.6 67.2 -56.1 -32.7 -34.0 -4.5 -8.8 287 287 A D G 3 S+ 0 0 122 1,-0.2 -2,-0.1 -274,-0.0 -211,-0.0 0.712 106.8 39.7 -55.7 -26.8 -36.1 -7.7 -8.7 288 288 A I G X >S+ 0 0 47 -3,-2.0 3,-1.0 -4,-0.1 5,-0.5 0.288 86.5 137.3-109.2 13.5 -33.0 -9.8 -7.9 289 289 A A T < 5 + 0 0 38 -3,-1.4 -276,-0.1 1,-0.2 -277,-0.1 -0.340 69.3 3.9 -77.7 134.8 -31.1 -7.5 -5.5 290 290 A G T 3 5S+ 0 0 71 -2,-0.1 -1,-0.2 -278,-0.1 -277,-0.0 0.579 99.4 105.2 76.2 14.6 -29.4 -8.7 -2.2 291 291 A K T < 5S- 0 0 141 -3,-1.0 -2,-0.1 58,-0.0 -1,-0.1 0.383 89.5-118.3-103.7 -4.1 -30.2 -12.3 -3.0 292 292 A G T 5S+ 0 0 24 -4,-0.1 57,-1.1 56,-0.1 59,-0.2 0.803 89.0 104.9 66.3 29.5 -26.7 -13.4 -4.1 293 293 A I < + 0 0 76 -5,-0.5 42,-0.3 55,-0.2 43,-0.3 0.729 41.6 106.8-107.0 -36.4 -28.0 -14.2 -7.6 294 294 A A S S- 0 0 3 -6,-0.4 41,-0.0 1,-0.1 -9,-0.0 -0.121 74.1-115.8 -54.3 146.9 -26.8 -11.3 -9.8 295 295 A N - 0 0 11 1,-0.1 3,-0.5 39,-0.1 4,-0.3 -0.754 25.3-167.4 -80.1 115.2 -23.9 -12.2 -12.3 296 296 A P > + 0 0 0 0, 0.0 4,-3.3 0, 0.0 3,-0.3 0.482 64.9 95.8 -83.3 0.3 -20.9 -10.1 -11.2 297 297 A I H > S+ 0 0 0 1,-0.2 4,-3.1 2,-0.2 5,-0.2 0.893 80.8 54.0 -61.4 -38.1 -19.0 -10.7 -14.4 298 298 A A H > S+ 0 0 5 -35,-1.5 4,-1.5 -3,-0.5 -1,-0.2 0.901 113.3 41.4 -64.6 -37.2 -20.2 -7.5 -16.0 299 299 A Q H > S+ 0 0 0 -4,-0.3 4,-2.1 -3,-0.3 -2,-0.2 0.950 114.1 52.6 -76.5 -43.6 -19.0 -5.4 -13.1 300 300 A I H X S+ 0 0 0 -4,-3.3 4,-1.3 1,-0.2 -2,-0.2 0.915 111.3 47.3 -51.8 -48.4 -15.8 -7.4 -12.7 301 301 A L H X S+ 0 0 22 -4,-3.1 4,-2.4 -5,-0.2 -1,-0.2 0.807 105.7 59.2 -68.8 -29.9 -15.1 -6.8 -16.5 302 302 A S H X S+ 0 0 0 -4,-1.5 4,-2.1 -5,-0.2 -1,-0.2 0.866 103.9 51.8 -59.1 -44.3 -15.9 -3.1 -16.0 303 303 A A H X S+ 0 0 0 -4,-2.1 4,-2.2 2,-0.2 -2,-0.2 0.835 107.3 52.1 -61.4 -30.8 -13.1 -3.0 -13.5 304 304 A A H X S+ 0 0 0 -4,-1.3 4,-2.3 2,-0.2 -2,-0.2 0.899 108.4 50.7 -74.7 -33.4 -10.8 -4.6 -16.1 305 305 A L H X S+ 0 0 16 -4,-2.4 4,-3.3 2,-0.2 5,-0.5 0.915 108.9 52.7 -63.5 -40.5 -11.8 -1.9 -18.6 306 306 A M H X>S+ 0 0 0 -4,-2.1 4,-2.1 2,-0.2 5,-1.9 0.946 108.9 49.1 -58.6 -51.0 -11.0 0.7 -16.0 307 307 A L H <5S+ 0 0 0 -4,-2.2 6,-3.6 3,-0.2 -2,-0.2 0.927 118.5 40.0 -52.8 -47.7 -7.5 -0.8 -15.4 308 308 A R H <5S+ 0 0 51 -4,-2.3 4,-0.4 4,-0.2 -2,-0.2 0.963 124.7 31.0 -69.4 -51.5 -6.8 -0.9 -19.1 309 309 A H H <5S+ 0 0 57 -4,-3.3 -3,-0.2 -5,-0.2 -2,-0.2 0.829 133.0 21.8 -88.3 -37.5 -8.2 2.3 -20.4 310 310 A S T <5S+ 0 0 10 -4,-2.1 -3,-0.2 -5,-0.5 -2,-0.1 0.804 129.5 36.7 -96.3 -40.7 -7.8 4.7 -17.4 311 311 A L S + 0 0 47 -6,-3.6 4,-2.6 1,-0.2 -1,-0.2 -0.674 15.9 162.1-116.6 72.8 -2.7 -1.4 -16.4 314 314 A E H > S+ 0 0 104 -2,-0.6 4,-2.9 1,-0.2 5,-0.2 0.919 72.0 50.4 -63.3 -43.5 -3.0 -3.6 -19.4 315 315 A E H > S+ 0 0 134 1,-0.2 4,-2.1 2,-0.2 -1,-0.2 0.880 111.5 47.8 -60.6 -47.2 -1.6 -6.7 -17.7 316 316 A A H > S+ 0 0 0 2,-0.2 4,-1.8 1,-0.2 -1,-0.2 0.927 111.9 50.0 -59.4 -47.6 -3.9 -6.4 -14.8 317 317 A A H X S+ 0 0 0 -4,-2.6 4,-1.9 1,-0.2 -2,-0.2 0.932 112.2 48.4 -56.8 -44.6 -6.9 -5.8 -17.1 318 318 A S H X S+ 0 0 23 -4,-2.9 4,-2.1 1,-0.2 -1,-0.2 0.840 105.9 56.9 -68.1 -33.6 -6.0 -8.9 -19.1 319 319 A A H X S+ 0 0 0 -4,-2.1 4,-1.8 1,-0.2 -1,-0.2 0.910 107.8 47.6 -64.9 -42.3 -5.5 -11.1 -16.0 320 320 A I H X S+ 0 0 0 -4,-1.8 4,-2.2 2,-0.2 -2,-0.2 0.907 110.6 53.1 -62.1 -42.2 -9.1 -10.3 -14.8 321 321 A E H X S+ 0 0 54 -4,-1.9 4,-2.4 1,-0.2 -2,-0.2 0.908 111.1 45.1 -61.6 -42.4 -10.5 -11.1 -18.4 322 322 A R H X S+ 0 0 99 -4,-2.1 4,-1.9 2,-0.2 -1,-0.2 0.817 108.6 55.7 -72.5 -29.0 -8.8 -14.5 -18.4 323 323 A A H X S+ 0 0 0 -4,-1.8 4,-2.0 2,-0.2 -2,-0.2 0.862 110.0 48.4 -68.7 -37.0 -10.0 -15.2 -14.8 324 324 A V H X S+ 0 0 4 -4,-2.2 4,-2.3 2,-0.2 -2,-0.2 0.914 109.8 51.4 -58.3 -45.9 -13.5 -14.5 -16.2 325 325 A T H X S+ 0 0 78 -4,-2.4 4,-1.9 1,-0.2 -2,-0.2 0.932 109.1 52.4 -61.6 -34.3 -12.8 -16.8 -19.2 326 326 A K H X S+ 0 0 87 -4,-1.9 4,-0.9 1,-0.2 -1,-0.2 0.932 107.1 49.4 -75.3 -42.7 -11.8 -19.4 -16.7 327 327 A A H ><>S+ 0 0 0 -4,-2.0 5,-2.8 1,-0.2 3,-1.2 0.942 111.2 51.1 -45.7 -59.1 -14.9 -19.2 -14.7 328 328 A L H 3<5S+ 0 0 34 -4,-2.3 3,-0.3 1,-0.3 -2,-0.2 0.715 116.1 40.0 -57.3 -30.8 -17.0 -19.5 -17.8 329 329 A N H 3<5S+ 0 0 116 -4,-1.9 -1,-0.3 -3,-0.2 -2,-0.2 0.453 111.6 57.6 -99.8 3.6 -15.1 -22.6 -19.0 330 330 A S T <<5S- 0 0 53 -3,-1.2 -2,-0.2 -4,-0.9 -1,-0.1 0.054 120.6 -95.3-119.3 25.9 -14.8 -24.3 -15.5 331 331 A G T 5S+ 0 0 37 -3,-0.3 2,-0.8 1,-0.2 -3,-0.2 0.728 82.6 133.5 68.0 26.0 -18.6 -24.4 -14.7 332 332 A Y < + 0 0 70 -5,-2.8 2,-0.4 -6,-0.2 -1,-0.2 -0.804 29.1 136.8-103.0 86.6 -18.7 -21.2 -12.7 333 333 A L - 0 0 19 -2,-0.8 14,-2.1 12,-0.4 2,-0.1 -0.982 50.5-124.2-129.8 142.4 -21.8 -19.5 -14.2 334 334 A T > - 0 0 0 -2,-0.4 3,-1.6 12,-0.2 4,-0.2 -0.342 41.9 -90.6 -77.6 169.4 -24.6 -17.7 -12.4 335 335 A G G > S+ 0 0 13 12,-0.5 3,-1.2 -42,-0.3 7,-0.1 0.736 119.7 58.8 -53.0 -37.2 -28.3 -18.9 -12.9 336 336 A E G 3 S+ 0 0 74 -43,-0.3 -1,-0.3 1,-0.3 4,-0.1 0.598 101.2 57.2 -76.0 -9.7 -29.2 -16.7 -15.9 337 337 A L G < S+ 0 0 1 -3,-1.6 2,-0.4 2,-0.1 -1,-0.3 0.467 95.6 81.1 -92.5 -3.3 -26.4 -18.2 -18.0 338 338 A L S < S- 0 0 13 -3,-1.2 5,-0.1 -4,-0.2 -223,-0.0 -0.875 83.0-116.5-113.1 138.4 -27.7 -21.8 -17.6 339 339 A S >> - 0 0 32 -2,-0.4 3,-2.2 1,-0.1 4,-0.9 -0.170 43.9 -97.7 -62.4 162.3 -30.5 -23.5 -19.5 340 340 A S T 34 S+ 0 0 96 1,-0.3 3,-0.3 2,-0.2 4,-0.1 0.824 124.4 53.5 -66.8 -24.7 -33.5 -24.4 -17.3 341 341 A D T 34 S+ 0 0 119 1,-0.2 -1,-0.3 2,-0.1 3,-0.1 0.491 114.5 42.4 -78.4 -2.5 -32.3 -28.1 -16.8 342 342 A Q T X4 S+ 0 0 78 -3,-2.2 3,-2.8 -7,-0.1 -2,-0.2 0.427 80.4 104.6-121.7 -4.6 -28.9 -26.9 -15.7 343 343 A R G >< + 0 0 117 -4,-0.9 3,-1.0 -3,-0.3 -2,-0.1 0.583 68.9 69.9 -56.5 -15.4 -30.1 -24.1 -13.4 344 344 A H G 3 S+ 0 0 148 1,-0.2 -1,-0.3 -4,-0.1 -2,-0.1 0.658 89.8 62.3 -77.7 -18.1 -29.3 -26.2 -10.3 345 345 A K G < S+ 0 0 89 -3,-2.8 -12,-0.4 -10,-0.1 -1,-0.2 0.350 79.1 137.2 -81.8 11.3 -25.5 -25.8 -11.1 346 346 A A < - 0 0 39 -3,-1.0 2,-0.3 -14,-0.1 -12,-0.2 -0.232 44.1-147.4 -67.0 137.4 -25.9 -22.0 -10.6 347 347 A K - 0 0 42 -14,-2.1 -12,-0.5 -54,-0.1 2,-0.1 -0.783 17.9-119.6 -96.6 152.1 -23.2 -20.2 -8.6 348 348 A T > - 0 0 60 -2,-0.3 4,-2.6 -14,-0.1 -55,-0.2 -0.403 29.3-101.5 -82.2 168.8 -24.0 -17.2 -6.4 349 349 A T H > S+ 0 0 3 -57,-1.1 4,-2.4 2,-0.2 5,-0.2 0.915 124.5 48.3 -53.3 -54.5 -22.5 -13.8 -6.9 350 350 A V H > S+ 0 0 74 1,-0.2 4,-2.6 2,-0.2 5,-0.2 0.933 111.0 51.5 -51.5 -48.0 -20.0 -14.3 -4.0 351 351 A Q H > S+ 0 0 74 2,-0.2 4,-2.3 1,-0.2 -2,-0.2 0.885 110.1 49.8 -58.7 -41.0 -19.0 -17.7 -5.5 352 352 A M H X S+ 0 0 0 -4,-2.6 4,-2.6 2,-0.2 5,-0.2 0.973 114.2 43.1 -62.4 -53.1 -18.4 -16.1 -8.9 353 353 A G H X S+ 0 0 0 -4,-2.4 4,-2.3 1,-0.2 -2,-0.2 0.830 112.9 53.8 -61.0 -37.0 -16.2 -13.3 -7.5 354 354 A D H X S+ 0 0 74 -4,-2.6 4,-2.2 -5,-0.2 -1,-0.2 0.917 112.4 43.9 -63.4 -45.9 -14.4 -15.7 -5.2 355 355 A F H X S+ 0 0 37 -4,-2.3 4,-2.9 -5,-0.2 -2,-0.2 0.934 113.9 48.3 -61.7 -52.8 -13.5 -18.0 -8.1 356 356 A I H X S+ 0 0 0 -4,-2.6 4,-1.7 1,-0.2 -2,-0.2 0.922 114.3 46.2 -61.5 -43.8 -12.5 -15.2 -10.4 357 357 A A H X S+ 0 0 5 -4,-2.3 4,-2.2 2,-0.2 -1,-0.2 0.863 111.8 52.0 -65.3 -38.4 -10.3 -13.5 -7.7 358 358 A D H X S+ 0 0 96 -4,-2.2 4,-2.9 1,-0.2 -2,-0.2 0.950 107.3 53.4 -59.8 -45.8 -8.7 -16.9 -6.8 359 359 A A H <>S+ 0 0 9 -4,-2.9 5,-2.4 2,-0.2 4,-0.3 0.869 109.1 47.7 -54.5 -42.9 -8.0 -17.4 -10.5 360 360 A V H ><5S+ 0 0 0 -4,-1.7 3,-1.6 1,-0.2 -1,-0.2 0.938 112.7 49.4 -64.3 -46.7 -6.2 -14.0 -10.7 361 361 A K H 3<5S+ 0 0 137 -4,-2.2 -2,-0.2 1,-0.3 -1,-0.2 0.895 105.9 57.9 -58.0 -40.6 -4.2 -14.9 -7.5 362 362 A A T 3<5S- 0 0 89 -4,-2.9 -1,-0.3 -5,-0.1 -2,-0.2 0.520 122.3-103.6 -74.6 -4.2 -3.3 -18.3 -9.0 363 363 A G T < 5 0 0 44 -3,-1.6 -3,-0.2 -4,-0.3 -2,-0.1 0.637 360.0 360.0 91.5 16.5 -1.6 -16.7 -12.0 364 364 A V < 0 0 42 -5,-2.4 -4,-0.2 -45,-0.0 -3,-0.1 0.799 360.0 360.0 -46.7 360.0 -4.3 -17.2 -14.7