==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 05-NOV-04 1WBQ . COMPND 2 MOLECULE: XAA-PRO AMINOPEPTIDASE; . SOURCE 2 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI; . AUTHOR S.C.GRAHAM,C.S.BOND,H.C.FREEMAN,J.M.GUSS . 1756 4 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 74161.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 1212 69.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 56 3.2 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 228 13.0 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 8 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 16 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 4 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 4 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 111 6.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 165 9.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 540 30.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 20 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 4 8 0 12 0 0 4 0 8 4 0 0 4 0 4 0 0 0 4 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 4 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 12 12 5 12 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 8 4 8 0 2 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A S 0 0 78 0, 0.0 2,-0.3 0, 0.0 178,-0.0 0.000 360.0 360.0 360.0 163.7 -6.9 -21.3 37.9 2 2 A E - 0 0 127 0, 0.0 2,-0.5 0, 0.0 180,-0.1 -0.931 360.0 -88.6-152.5 175.3 -4.4 -20.9 35.1 3 3 A I - 0 0 16 -2,-0.3 2,-0.1 263,-0.1 263,-0.0 -0.822 44.9-133.2 -93.9 129.9 -2.7 -22.5 32.0 4 4 A S > - 0 0 21 -2,-0.5 4,-1.9 1,-0.1 3,-0.3 -0.369 18.2-115.1 -81.0 158.1 0.4 -24.5 32.8 5 5 A R H > S+ 0 0 114 1,-0.2 4,-1.8 2,-0.2 5,-0.1 0.859 119.8 55.3 -53.7 -39.5 3.8 -24.4 31.0 6 6 A Q H > S+ 0 0 120 2,-0.2 4,-2.7 1,-0.2 -1,-0.2 0.845 103.5 53.9 -67.5 -35.4 3.1 -28.0 30.1 7 7 A E H > S+ 0 0 6 -3,-0.3 4,-2.3 2,-0.2 -2,-0.2 0.935 107.3 49.7 -65.4 -45.9 -0.3 -27.1 28.5 8 8 A F H X S+ 0 0 26 -4,-1.9 4,-2.0 1,-0.2 -2,-0.2 0.899 112.9 49.2 -58.4 -39.4 1.3 -24.5 26.2 9 9 A Q H X S+ 0 0 67 -4,-1.8 4,-2.4 2,-0.2 -2,-0.2 0.926 108.5 51.7 -64.0 -47.2 3.9 -27.1 25.3 10 10 A R H X S+ 0 0 133 -4,-2.7 4,-2.1 1,-0.2 -2,-0.2 0.882 109.3 51.6 -55.5 -41.7 1.1 -29.7 24.5 11 11 A R H X S+ 0 0 11 -4,-2.3 4,-2.0 2,-0.2 -1,-0.2 0.928 109.0 48.8 -63.9 -46.8 -0.6 -27.2 22.3 12 12 A R H X S+ 0 0 3 -4,-2.0 4,-2.4 1,-0.2 -2,-0.2 0.921 113.2 48.0 -59.1 -44.7 2.5 -26.4 20.3 13 13 A Q H X S+ 0 0 74 -4,-2.4 4,-2.5 2,-0.2 -1,-0.2 0.839 106.8 56.2 -65.4 -34.4 3.1 -30.2 19.8 14 14 A A H X S+ 0 0 42 -4,-2.1 4,-1.0 -5,-0.2 -1,-0.2 0.898 110.8 45.2 -65.7 -37.8 -0.5 -30.8 18.8 15 15 A L H >X S+ 0 0 4 -4,-2.0 3,-0.6 2,-0.2 4,-0.6 0.939 112.5 50.4 -65.6 -48.2 -0.0 -28.2 16.0 16 16 A V H >< S+ 0 0 4 -4,-2.4 3,-1.2 1,-0.2 -2,-0.2 0.875 103.6 60.4 -59.0 -39.0 3.4 -29.7 15.0 17 17 A E H 3< S+ 0 0 133 -4,-2.5 -1,-0.2 1,-0.3 -2,-0.2 0.870 106.9 46.4 -56.1 -37.8 1.8 -33.2 14.9 18 18 A Q H << S+ 0 0 98 -4,-1.0 -1,-0.3 -3,-0.6 -2,-0.2 0.545 96.3 97.3 -82.8 -8.3 -0.6 -31.9 12.2 19 19 A M S << S- 0 0 6 -3,-1.2 3,-0.1 -4,-0.6 4,-0.1 -0.523 78.6-111.7 -83.1 149.7 2.2 -30.2 10.1 20 20 A Q - 0 0 96 -2,-0.2 3,-0.3 1,-0.1 46,-0.2 -0.409 41.2 -96.7 -67.8 150.8 3.9 -31.6 7.1 21 21 A P S S+ 0 0 73 0, 0.0 47,-0.2 0, 0.0 46,-0.2 -0.431 109.9 34.8 -66.1 149.4 7.6 -32.6 7.5 22 22 A G S S+ 0 0 14 44,-1.6 103,-2.6 1,-0.2 104,-1.6 0.941 100.0 118.0 68.0 49.2 10.0 -29.9 6.2 23 23 A S E -Ab 66 126A 0 43,-2.2 43,-3.0 -3,-0.3 2,-0.3 -0.933 49.5-151.3-142.5 164.2 7.7 -27.0 7.3 24 24 A A E -Ab 65 127A 0 102,-1.6 104,-3.3 -2,-0.3 2,-0.4 -0.999 8.3-149.6-138.3 138.4 7.5 -24.0 9.6 25 25 A A E -Ab 64 128A 0 39,-2.5 39,-2.3 -2,-0.3 2,-0.5 -0.917 11.3-157.6-107.9 133.9 4.5 -22.3 11.3 26 26 A L E -Ab 63 129A 1 102,-2.6 104,-0.5 -2,-0.4 2,-0.5 -0.956 10.7-178.9-116.5 120.5 4.6 -18.6 11.9 27 27 A I E -A 62 0A 0 35,-2.5 35,-3.1 -2,-0.5 2,-0.3 -0.975 13.2-157.5-126.5 115.0 2.4 -17.1 14.6 28 28 A F E -A 61 0A 12 -2,-0.5 21,-0.3 33,-0.2 33,-0.2 -0.701 13.3-121.7-100.6 142.4 2.6 -13.3 15.1 29 29 A A - 0 0 0 31,-2.7 30,-0.1 -2,-0.3 108,-0.1 -0.317 38.5 -95.1 -70.4 159.6 1.7 -11.1 18.1 30 30 A A - 0 0 7 27,-0.1 29,-0.3 1,-0.1 2,-0.1 -0.465 40.8-115.5 -71.4 147.0 -0.9 -8.4 17.9 31 31 A P - 0 0 56 0, 0.0 13,-0.2 0, 0.0 2,-0.1 -0.443 34.4 -95.7 -74.4 157.4 0.4 -4.9 17.2 32 32 A E - 0 0 89 -2,-0.1 2,-0.4 11,-0.1 11,-0.0 -0.407 42.7-137.0 -65.8 154.7 -0.0 -2.1 19.7 33 33 A V - 0 0 33 8,-0.4 8,-2.3 -2,-0.1 2,-0.1 -0.973 4.9-128.1-131.7 122.7 -3.1 0.0 19.1 34 34 A T E +F 40 0B 79 -2,-0.4 6,-0.3 6,-0.2 3,-0.1 -0.423 20.8 178.6 -69.7 137.4 -3.5 3.8 19.3 35 35 A R E S- 0 0 35 4,-2.8 2,-0.3 1,-0.2 5,-0.2 0.773 76.3 -20.0 -98.3 -52.4 -6.2 5.3 21.4 36 36 A S E > S-F 39 0B 9 3,-1.5 3,-2.4 450,-0.1 -1,-0.2 -0.871 107.5 -45.2-159.6 127.9 -5.4 9.0 20.7 37 37 A A T 3 S- 0 0 56 -2,-0.3 -2,-0.1 1,-0.3 -1,-0.1 -0.293 127.2 -9.1 52.1-119.1 -2.2 10.6 19.5 38 38 A D T 3 S+ 0 0 95 763,-0.2 2,-0.3 -4,-0.1 -1,-0.3 0.482 115.7 96.5 -89.4 -2.7 0.7 9.0 21.4 39 39 A S E < -F 36 0B 18 -3,-2.4 -4,-2.8 762,-0.1 -3,-1.5 -0.690 59.0-156.2 -91.5 143.1 -1.4 7.2 23.9 40 40 A E E -F 34 0B 76 -2,-0.3 630,-0.3 -6,-0.3 -6,-0.2 -0.830 19.3-109.2-117.4 150.1 -2.3 3.5 23.4 41 41 A Y - 0 0 19 -8,-2.3 -8,-0.4 -2,-0.3 3,-0.1 -0.381 58.2 -76.8 -64.3 155.5 -5.1 1.2 24.6 42 42 A P - 0 0 28 0, 0.0 -1,-0.1 0, 0.0 2,-0.0 -0.354 65.4 -97.2 -53.6 132.9 -4.2 -1.5 27.1 43 43 A Y - 0 0 44 -3,-0.1 2,-0.5 13,-0.1 -11,-0.1 -0.277 39.4-169.2 -63.3 135.5 -2.4 -4.2 25.2 44 44 A R - 0 0 21 -13,-0.2 3,-0.1 -3,-0.1 2,-0.1 -0.971 17.5-136.1-126.8 113.2 -4.4 -7.2 24.1 45 45 A Q - 0 0 3 -2,-0.5 11,-0.1 1,-0.1 -16,-0.1 -0.358 31.0 -95.0 -66.7 144.2 -2.5 -10.2 22.7 46 46 A N > - 0 0 12 1,-0.1 4,-3.0 -2,-0.1 5,-0.2 -0.393 34.4-130.6 -54.1 132.4 -3.7 -12.0 19.6 47 47 A S H > S+ 0 0 4 1,-0.2 4,-2.4 2,-0.2 -1,-0.1 0.864 105.1 47.5 -63.2 -39.4 -5.7 -15.0 20.9 48 48 A D H > S+ 0 0 6 2,-0.2 4,-1.3 1,-0.2 -1,-0.2 0.901 114.0 46.5 -69.4 -41.1 -3.9 -17.5 18.7 49 49 A F H > S+ 0 0 0 -21,-0.3 4,-0.6 1,-0.2 3,-0.3 0.924 114.7 49.0 -64.8 -42.9 -0.4 -16.2 19.7 50 50 A W H >X S+ 0 0 49 -4,-3.0 4,-2.5 1,-0.2 3,-1.2 0.901 103.5 60.9 -58.1 -46.0 -1.6 -16.2 23.3 51 51 A Y H 3< S+ 0 0 10 -4,-2.4 -1,-0.2 1,-0.3 -2,-0.2 0.847 111.9 37.4 -53.4 -39.2 -2.9 -19.8 23.0 52 52 A F H 3< S+ 0 0 0 -4,-1.3 -1,-0.3 -3,-0.3 -2,-0.2 0.510 135.2 15.9 -91.7 -4.4 0.5 -21.2 22.1 53 53 A T H << S- 0 0 7 -3,-1.2 -3,-0.2 -4,-0.6 -2,-0.2 0.635 70.6-139.5-138.6 -35.7 2.6 -18.9 24.5 54 54 A G < + 0 0 25 -4,-2.5 2,-0.5 -5,-0.3 -4,-0.1 0.790 57.9 145.0 59.3 29.3 0.8 -17.1 27.3 55 55 A F - 0 0 15 -6,-0.3 -1,-0.2 2,-0.1 -2,-0.1 -0.890 39.0-162.9-108.6 122.1 3.2 -14.2 26.3 56 56 A N + 0 0 87 -2,-0.5 -13,-0.1 -3,-0.1 -1,-0.1 -0.109 50.1 103.6-103.6 35.5 1.8 -10.6 26.6 57 57 A E - 0 0 22 -13,-0.0 3,-0.2 -2,-0.0 -27,-0.1 -0.865 60.0-132.2-113.0 149.2 4.3 -8.5 24.5 58 58 A P S S+ 0 0 7 0, 0.0 21,-0.4 0, 0.0 3,-0.1 -0.319 84.3 49.3 -80.5 176.9 3.9 -7.1 21.0 59 59 A E S S+ 0 0 84 -29,-0.3 2,-0.3 1,-0.2 20,-0.2 0.928 84.5 123.2 54.3 52.4 6.7 -7.4 18.4 60 60 A A - 0 0 0 18,-0.2 -31,-2.7 -3,-0.2 2,-0.4 -0.986 40.0-168.9-140.5 149.4 7.1 -11.2 18.9 61 61 A V E -AC 28 77A 0 16,-2.3 16,-2.8 -2,-0.3 2,-0.5 -0.989 12.5-148.1-142.6 125.1 6.8 -14.1 16.5 62 62 A L E -AC 27 76A 0 -35,-3.1 -35,-2.5 -2,-0.4 2,-0.5 -0.866 15.4-167.0 -94.5 127.3 6.6 -17.8 17.4 63 63 A V E -AC 26 75A 0 12,-3.0 12,-2.7 -2,-0.5 2,-0.6 -0.959 4.1-168.1-119.7 114.6 8.2 -20.0 14.8 64 64 A L E -AC 25 74A 5 -39,-2.3 -39,-2.5 -2,-0.5 2,-0.5 -0.905 8.8-164.0-102.9 118.9 7.6 -23.8 14.9 65 65 A I E -AC 24 73A 9 8,-3.2 8,-2.4 -2,-0.6 2,-0.6 -0.908 8.4-168.3-111.2 123.8 9.9 -25.8 12.7 66 66 A K E +AC 23 72A 7 -43,-3.0 -43,-2.2 -2,-0.5 -44,-1.6 -0.921 10.7 173.6-110.1 105.3 9.2 -29.4 11.7 67 67 A S S S- 0 0 68 4,-1.4 2,-0.2 -2,-0.6 -1,-0.2 0.927 70.3 -31.6 -71.7 -47.5 12.2 -31.1 10.0 68 68 A D S S- 0 0 57 3,-1.8 -1,-0.2 -47,-0.2 -45,-0.1 -0.841 82.3 -65.5-156.0-168.2 10.5 -34.5 10.0 69 69 A D S S+ 0 0 132 -2,-0.2 3,-0.1 1,-0.2 -49,-0.0 0.658 131.8 27.7 -69.1 -16.4 8.1 -36.7 12.0 70 70 A T S S+ 0 0 105 1,-0.1 2,-0.5 0, 0.0 -1,-0.2 0.714 111.7 68.5-109.8 -33.5 10.4 -37.0 15.0 71 71 A H + 0 0 114 2,-0.0 -3,-1.8 -5,-0.0 -4,-1.4 -0.809 54.3 140.2-102.4 122.4 12.5 -33.8 14.9 72 72 A N E +C 66 0A 52 -2,-0.5 2,-0.3 -6,-0.2 -6,-0.2 -0.982 17.7 179.9-148.5 157.7 11.0 -30.3 15.6 73 73 A H E -C 65 0A 69 -8,-2.4 -8,-3.2 -2,-0.3 2,-0.4 -0.969 19.0-124.2-154.3 169.5 12.1 -27.1 17.4 74 74 A S E -C 64 0A 7 -2,-0.3 32,-0.9 -10,-0.2 31,-0.4 -0.930 12.6-169.7-124.1 141.5 10.9 -23.6 18.2 75 75 A V E -Cd 63 106A 0 -12,-2.7 -12,-3.0 -2,-0.4 2,-0.5 -1.000 9.3-159.0-128.0 130.1 12.3 -20.1 17.6 76 76 A L E -Cd 62 107A 0 30,-2.7 32,-3.3 -2,-0.4 2,-0.5 -0.942 4.1-159.2-107.2 129.1 10.9 -17.0 19.3 77 77 A F E +Cd 61 108A 0 -16,-2.8 -16,-2.3 -2,-0.5 2,-0.3 -0.939 33.1 149.5 -96.7 127.0 11.5 -13.5 17.9 78 78 A N E - d 0 109A 0 30,-2.4 32,-1.9 -2,-0.5 33,-0.2 -0.964 50.1 -71.1-152.6 166.9 10.9 -11.0 20.7 79 79 A R - 0 0 33 -21,-0.4 15,-0.6 -2,-0.3 3,-0.1 -0.352 51.7-117.4 -67.7 139.2 12.1 -7.6 21.8 80 80 A V - 0 0 67 14,-0.2 2,-0.4 1,-0.1 14,-0.1 -0.278 31.5 -96.1 -69.8 155.2 15.6 -7.3 23.2 81 81 A R + 0 0 137 12,-0.1 2,-0.4 10,-0.0 -1,-0.1 -0.632 47.1 179.2 -69.8 129.1 16.4 -6.3 26.8 82 82 A D > - 0 0 72 -2,-0.4 4,-1.6 1,-0.2 5,-0.3 -0.980 25.1-150.3-139.1 121.6 17.2 -2.5 26.8 83 83 A L H > S+ 0 0 136 -2,-0.4 4,-2.1 2,-0.2 3,-0.3 0.953 97.6 35.7 -55.3 -58.0 18.0 -0.6 30.0 84 84 A T H > S+ 0 0 86 1,-0.2 4,-2.0 2,-0.2 -1,-0.2 0.958 115.4 53.0 -62.6 -55.3 16.7 2.8 28.9 85 85 A A H > S+ 0 0 13 1,-0.2 4,-2.0 2,-0.2 -1,-0.2 0.730 114.0 44.4 -56.4 -26.0 13.7 1.5 26.9 86 86 A E H X S+ 0 0 17 -4,-1.6 4,-1.5 -3,-0.3 597,-0.3 0.855 103.6 59.9 -89.2 -41.8 12.4 -0.6 29.9 87 87 A I H < S+ 0 0 59 -4,-2.1 595,-2.5 -5,-0.3 596,-0.5 0.905 122.8 30.2 -45.5 -44.7 13.0 2.1 32.6 88 88 A W H < S+ 0 0 73 -4,-2.0 595,-2.5 594,-0.2 2,-0.7 0.946 131.5 28.6 -74.3 -80.7 10.5 4.0 30.4 89 89 A F H < S- 0 0 137 -4,-2.0 -2,-0.2 1,-0.2 -3,-0.2 -0.037 113.2 -96.1 -88.1 31.7 8.2 1.5 28.6 90 90 A G < - 0 0 2 -4,-1.5 -1,-0.2 -2,-0.7 -2,-0.1 0.266 56.3 -44.3 79.4 158.8 8.2 -1.4 31.2 91 91 A R - 0 0 116 -3,-0.1 2,-0.4 -4,-0.1 3,-0.1 -0.172 49.0-154.7 -62.8 147.8 10.1 -4.6 31.6 92 92 A R - 0 0 40 1,-0.1 -6,-0.0 -10,-0.1 -1,-0.0 -0.965 18.8-134.9-123.9 142.1 10.8 -7.0 28.7 93 93 A L > - 0 0 33 -2,-0.4 4,-0.6 1,-0.1 3,-0.1 0.947 44.4-173.2 -57.3 -52.0 11.4 -10.7 28.8 94 94 A G H > - 0 0 0 -15,-0.6 4,-0.6 1,-0.1 -14,-0.2 -0.125 38.1 -67.9 78.2-178.1 14.3 -10.5 26.3 95 95 A Q H 4 S+ 0 0 36 2,-0.2 -1,-0.1 1,-0.1 12,-0.1 0.774 121.4 56.5 -83.5 -30.9 16.3 -13.3 24.7 96 96 A D H 4 S+ 0 0 158 1,-0.2 4,-0.4 -3,-0.1 -1,-0.1 0.931 115.5 34.2 -70.4 -45.6 18.2 -14.8 27.7 97 97 A A H X S+ 0 0 49 -4,-0.6 4,-2.5 1,-0.2 5,-0.2 0.651 100.4 82.1 -82.4 -17.0 15.2 -15.6 29.9 98 98 A A H X S+ 0 0 0 -4,-0.6 4,-3.1 1,-0.2 6,-0.5 0.880 83.3 55.8 -63.9 -46.2 12.8 -16.5 27.1 99 99 A P H >>S+ 0 0 42 0, 0.0 4,-0.8 0, 0.0 5,-0.8 0.918 117.7 35.0 -51.6 -48.0 13.8 -20.2 26.4 100 100 A E H 45S+ 0 0 137 -4,-0.4 -2,-0.2 3,-0.2 -3,-0.1 0.919 121.2 47.8 -74.0 -44.8 13.2 -21.2 30.0 101 101 A K H <5S+ 0 0 112 -4,-2.5 -3,-0.2 1,-0.2 -1,-0.1 0.933 127.4 23.5 -62.7 -51.3 10.3 -18.9 30.6 102 102 A L H <5S- 0 0 18 -4,-3.1 -1,-0.2 -5,-0.2 -2,-0.2 0.370 104.3-118.3-101.2 1.4 8.3 -19.7 27.5 103 103 A G T <5 + 0 0 30 -4,-0.8 2,-0.3 -5,-0.4 -3,-0.2 0.880 61.9 145.2 64.7 40.7 9.8 -23.2 26.8 104 104 A V < - 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