==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=6-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 03-FEB-98 2WEA . COMPND 2 MOLECULE: PENICILLOPEPSIN; . SOURCE 2 ORGANISM_SCIENTIFIC: PENICILLIUM JANTHINELLUM; . AUTHOR J.DING,M.E.FRASER,M.N.G.JAMES . 323 1 1 1 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 12593.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 234 72.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 19 5.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 110 34.1 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 4 1.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 4 1.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 41 12.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 38 11.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 22 6.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 4 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 2 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 4 3 4 2 2 1 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 1 0 1 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A A 0 0 124 0, 0.0 2,-0.3 0, 0.0 147,-0.2 0.000 360.0 360.0 360.0 155.1 36.8 31.0 1.7 2 2 A A B +a 148 0A 33 145,-2.6 147,-2.9 142,-0.2 148,-0.3 -0.665 360.0 153.6-102.2 160.4 35.4 27.5 1.9 3 3 A S + 0 0 59 -2,-0.3 2,-0.3 145,-0.2 165,-0.2 -0.947 12.6 177.0-162.9 167.1 31.9 26.0 1.9 4 4 A G E -B 167 0B 9 163,-2.2 163,-3.1 -2,-0.3 2,-0.5 -0.985 27.8-123.4-169.6 164.2 30.5 22.6 0.9 5 5 A V E -B 166 0B 67 88,-0.4 2,-0.5 -2,-0.3 161,-0.2 -0.976 20.4-165.9-118.4 117.4 27.4 20.5 0.8 6 6 A A E -B 165 0B 4 159,-3.3 159,-2.7 -2,-0.5 2,-0.5 -0.890 18.5-137.5-100.3 127.3 27.6 17.1 2.4 7 7 A T E -B 164 0B 71 -2,-0.5 2,-0.3 157,-0.2 157,-0.3 -0.771 16.8-161.4 -90.1 129.4 24.7 14.8 1.4 8 8 A N E -B 163 0B 0 155,-1.6 155,-2.3 -2,-0.5 11,-0.2 -0.766 2.2-162.3-105.6 154.3 23.0 12.8 4.1 9 9 A T E -G 18 0C 61 9,-1.8 9,-2.6 -2,-0.3 2,-0.1 -0.987 16.6-129.2-138.8 127.6 20.8 9.7 3.6 10 10 A P E -G 17 0C 24 0, 0.0 7,-0.2 0, 0.0 3,-0.1 -0.445 17.3-136.9 -74.2 146.5 18.4 8.2 6.1 11 11 A T > - 0 0 17 5,-2.4 3,-2.9 1,-0.2 149,-0.2 -0.302 61.6 -38.1 -82.6-175.6 18.6 4.5 6.9 12 12 A A G > S+ 0 0 71 1,-0.3 3,-1.7 2,-0.2 -1,-0.2 -0.130 135.5 0.2 -51.4 132.0 15.2 2.5 7.1 13 13 A N G 3 S- 0 0 53 1,-0.3 -1,-0.3 -3,-0.1 -2,-0.0 0.545 120.0 -81.7 63.0 15.8 12.5 4.5 8.8 14 14 A D G < S+ 0 0 0 -3,-2.9 -1,-0.3 2,-0.1 -2,-0.2 0.873 79.0 157.2 58.9 38.8 15.0 7.4 9.1 15 15 A E S < S- 0 0 75 -3,-1.7 2,-0.3 1,-0.2 285,-0.1 0.879 72.8 -13.9 -62.8 -34.6 16.5 5.7 12.3 16 16 A E - 0 0 5 -4,-0.1 -5,-2.4 201,-0.0 2,-0.4 -0.963 68.1-121.3-154.0 173.0 19.6 7.7 11.5 17 17 A Y E -G 10 0C 3 -2,-0.3 15,-0.5 197,-0.2 2,-0.4 -0.959 22.7-154.8-123.9 131.5 21.2 9.7 8.8 18 18 A I E -GH 9 31C 20 -9,-2.6 -9,-1.8 -2,-0.4 13,-0.2 -0.904 10.4-177.0-112.2 145.7 24.6 8.8 7.3 19 19 A T E - H 0 30C 0 11,-2.6 11,-2.4 -2,-0.4 -11,-0.2 -0.997 29.5-115.4-137.8 131.7 27.0 11.1 5.5 20 20 A P E - H 0 29C 62 0, 0.0 73,-0.4 0, 0.0 2,-0.4 -0.426 31.0-176.3 -71.9 143.3 30.3 10.1 3.9 21 21 A V E - H 0 28C 0 7,-2.4 7,-3.0 71,-0.1 2,-0.7 -0.995 18.9-141.4-142.4 125.9 33.6 11.4 5.4 22 22 A T E -IH 91 27C 44 69,-2.4 69,-2.5 -2,-0.4 2,-0.5 -0.861 21.1-177.1 -96.6 118.8 37.0 10.8 4.0 23 23 A I E > S-IH 90 26C 0 3,-3.0 3,-2.4 -2,-0.7 67,-0.2 -0.971 73.2 -18.8-118.8 117.2 39.6 10.2 6.7 24 24 A G T 3 S- 0 0 17 65,-2.3 -1,-0.2 -2,-0.5 34,-0.1 0.895 130.3 -53.0 54.6 35.7 43.3 9.7 5.6 25 25 A G T 3 S+ 0 0 65 64,-0.3 2,-0.5 1,-0.2 -1,-0.3 0.397 117.3 110.8 82.3 -8.9 41.9 8.8 2.2 26 26 A T E < -H 23 0C 56 -3,-2.4 -3,-3.0 32,-0.0 2,-0.5 -0.919 63.1-136.5 -99.4 129.8 39.4 6.1 3.4 27 27 A T E -H 22 0C 72 -2,-0.5 2,-0.3 -5,-0.3 -5,-0.3 -0.721 24.5-176.8 -89.3 122.2 35.7 7.0 3.1 28 28 A L E -H 21 0C 0 -7,-3.0 -7,-2.4 -2,-0.5 2,-0.8 -0.843 28.0-124.5-113.2 151.8 33.5 6.1 6.1 29 29 A N E -H 20 0C 64 -2,-0.3 90,-2.9 -9,-0.2 2,-0.3 -0.872 40.2-173.6 -99.2 105.6 29.7 6.5 6.5 30 30 A L E -H 19 0C 0 -11,-2.4 -11,-2.6 -2,-0.8 2,-0.8 -0.747 30.2-125.9-107.6 153.5 29.3 8.5 9.7 31 31 A N E -Hj 18 121C 17 89,-2.3 91,-1.8 -2,-0.3 2,-0.4 -0.832 29.8-140.2 -91.5 108.3 26.3 9.6 11.7 32 32 A F E - j 0 122C 1 -2,-0.8 2,-0.5 -15,-0.5 91,-0.2 -0.576 23.0-169.3 -74.6 130.3 26.6 13.4 12.1 33 33 A D E > - j 0 123C 12 89,-2.9 91,-2.4 -2,-0.4 3,-1.7 -0.895 26.0-174.2-133.3 106.1 25.6 14.3 15.6 34 34 A T T 3 S+ 0 0 1 -2,-0.5 157,-0.4 1,-0.3 92,-0.2 0.504 89.6 62.9 -74.4 -4.6 25.0 17.8 16.8 35 35 A G T 3 S+ 0 0 16 90,-0.1 2,-0.3 155,-0.1 -1,-0.3 0.248 100.4 60.2 -98.7 6.8 24.6 16.5 20.3 36 36 A S < - 0 0 10 -3,-1.7 89,-2.9 86,-0.1 88,-0.5 -0.968 56.6-160.4-134.4 149.0 28.2 15.2 20.5 37 37 A A + 0 0 2 92,-0.3 2,-0.3 -2,-0.3 93,-0.1 0.196 66.8 96.7-110.1 13.5 31.7 16.8 20.2 38 38 A D - 0 0 4 -5,-0.1 85,-1.4 92,-0.1 2,-0.6 -0.777 56.8-157.1-104.0 146.0 33.5 13.6 19.4 39 39 A L E +K 122 0C 4 -2,-0.3 64,-2.8 83,-0.3 2,-0.4 -0.951 31.4 168.7-117.0 98.6 34.6 12.3 16.0 40 40 A W E -Kl 121 103C 0 81,-1.9 81,-1.7 -2,-0.6 2,-0.3 -0.941 10.5-172.8-119.5 145.6 34.9 8.6 16.6 41 41 A V E -Kl 120 104C 0 62,-2.4 64,-3.0 -2,-0.4 79,-0.3 -0.961 33.3-104.0-137.8 149.4 35.4 5.8 14.1 42 42 A F - 0 0 0 77,-2.3 15,-2.6 -2,-0.3 2,-0.3 -0.465 55.1-178.4 -60.5 143.8 35.5 2.0 13.7 43 43 A S B > -p 57 0D 0 62,-0.4 3,-1.7 13,-0.3 15,-0.2 -0.885 46.4 -95.8-145.9 172.6 39.2 1.2 13.2 44 44 A T T 3 S+ 0 0 57 13,-2.1 14,-0.1 -2,-0.3 4,-0.1 0.439 113.2 74.1 -69.8 -4.9 41.8 -1.5 12.6 45 45 A E T 3 S+ 0 0 62 60,-0.4 -1,-0.3 12,-0.3 3,-0.1 0.508 78.9 89.0 -84.9 -12.4 42.3 -1.5 16.4 46 46 A L S < S- 0 0 6 -3,-1.7 5,-0.1 1,-0.1 61,-0.1 -0.562 101.0 -83.4 -75.1 160.8 39.0 -3.3 16.9 47 47 A P >> - 0 0 62 0, 0.0 3,-1.4 0, 0.0 4,-0.9 -0.299 44.1-115.9 -58.0 142.8 39.0 -7.1 16.9 48 48 A A H >> S+ 0 0 75 1,-0.3 4,-0.9 2,-0.2 3,-0.6 0.821 115.0 59.8 -52.3 -39.0 38.7 -8.2 13.3 49 49 A S H 34 S+ 0 0 94 1,-0.2 3,-0.3 2,-0.2 -1,-0.3 0.828 104.2 50.7 -62.3 -31.2 35.3 -9.7 13.9 50 50 A Q H <4 S+ 0 0 43 -3,-1.4 -1,-0.2 1,-0.2 -2,-0.2 0.661 102.6 60.9 -80.3 -15.0 34.0 -6.3 15.0 51 51 A Q H X< S+ 0 0 44 -4,-0.9 3,-1.7 -3,-0.6 -1,-0.2 0.719 79.5 109.9 -79.5 -25.4 35.3 -4.7 11.8 52 52 A S T 3< S+ 0 0 86 -4,-0.9 3,-0.1 -3,-0.3 -3,-0.0 -0.277 80.2 21.5 -56.4 135.8 33.2 -6.9 9.5 53 53 A G T 3 S+ 0 0 59 1,-0.3 2,-0.3 64,-0.0 -1,-0.3 0.522 113.1 88.5 81.7 11.8 30.4 -5.1 7.8 54 54 A H S < S- 0 0 25 -3,-1.7 2,-0.4 65,-0.1 -1,-0.3 -0.918 75.5-123.9-137.2 156.4 32.1 -1.7 8.2 55 55 A S - 0 0 54 -2,-0.3 2,-0.4 -26,-0.1 -13,-0.2 -0.815 42.0-157.2 -89.7 143.9 34.6 0.6 6.6 56 56 A V - 0 0 29 -2,-0.4 2,-0.4 -15,-0.1 -13,-0.3 -0.925 17.4-117.0-134.6 145.1 37.4 1.2 9.1 57 57 A Y B -p 43 0D 1 -15,-2.6 -13,-2.1 -2,-0.4 -12,-0.3 -0.684 21.2-158.6 -76.0 134.2 40.0 3.8 9.7 58 58 A N >> - 0 0 61 -2,-0.4 3,-1.0 -15,-0.2 4,-0.7 -0.875 9.4-177.1-116.2 96.1 43.5 2.5 9.4 59 59 A P H 3> + 0 0 6 0, 0.0 4,-2.3 0, 0.0 3,-0.2 0.787 69.5 76.5 -68.2 -24.4 45.7 5.0 11.3 60 60 A S H 34 S+ 0 0 103 1,-0.2 5,-0.1 2,-0.2 -2,-0.0 0.785 96.8 46.7 -57.3 -32.3 49.0 3.2 10.5 61 61 A A H <4 S- 0 0 76 -3,-1.0 -1,-0.2 1,-0.1 -37,-0.0 0.881 135.0 -3.7 -79.3 -39.0 49.1 4.6 7.0 62 62 A T H < S+ 0 0 65 -4,-0.7 -2,-0.2 -3,-0.2 2,-0.1 0.545 98.2 102.9-134.9 -16.7 48.3 8.3 7.5 63 63 A G < - 0 0 22 -4,-2.3 2,-0.6 -5,-0.3 25,-0.2 -0.445 55.8-139.6 -82.1 153.8 47.5 9.2 11.0 64 64 A K E -M 87 0C 152 23,-2.6 23,-2.4 -2,-0.1 -4,-0.1 -0.941 28.5-132.7-106.3 116.2 49.7 11.0 13.6 65 65 A E E -M 86 0C 117 -2,-0.6 2,-1.0 21,-0.2 21,-0.3 -0.322 4.4-145.2 -70.2 139.6 49.2 9.4 17.0 66 66 A L E > - 0 0 40 19,-2.8 3,-2.0 3,-0.1 19,-0.4 -0.859 33.0-140.2 -98.6 92.6 48.7 11.5 20.1 67 67 A S E 3 S+ 0 0 98 -2,-1.0 3,-0.1 1,-0.3 19,-0.0 -0.358 79.4 15.3 -60.8 136.4 50.6 9.2 22.3 68 68 A G E 3 S+ 0 0 67 1,-0.3 -1,-0.3 -2,-0.0 2,-0.2 0.338 96.1 126.9 87.0 -9.6 49.0 8.8 25.8 69 69 A Y E < + 0 0 44 -3,-2.0 16,-0.5 16,-0.2 -1,-0.3 -0.590 31.4 172.8 -87.0 148.0 45.6 10.2 24.7 70 70 A T E -MN 84 133C 75 63,-2.2 63,-3.1 -2,-0.2 2,-0.3 -0.887 14.4-162.4-141.8 171.1 42.4 8.4 25.2 71 71 A W E +M 83 0C 3 12,-1.6 12,-2.2 -2,-0.3 2,-0.3 -0.981 7.7 177.4-153.0 154.2 38.6 8.9 24.9 72 72 A S E -M 82 0C 78 -2,-0.3 2,-0.3 10,-0.2 10,-0.2 -0.947 6.6-168.3-161.9 141.0 35.6 7.2 26.2 73 73 A I E -M 81 0C 18 8,-2.8 8,-1.8 -2,-0.3 2,-0.4 -0.980 2.1-169.0-132.5 144.3 31.8 7.8 26.0 74 74 A S E -M 80 0C 107 -2,-0.3 2,-0.3 6,-0.2 6,-0.2 -0.993 9.0-155.0-135.9 134.3 29.0 6.2 28.0 75 75 A Y > - 0 0 76 4,-2.8 3,-2.2 -2,-0.4 -2,-0.0 -0.855 27.4-119.5-113.3 153.3 25.2 6.6 27.2 76 76 A G T 3 S+ 0 0 95 -2,-0.3 -1,-0.1 1,-0.3 -2,-0.0 0.659 113.4 63.3 -61.1 -19.2 22.1 6.2 29.4 77 77 A D T 3 S- 0 0 106 2,-0.1 -1,-0.3 1,-0.0 -3,-0.0 0.556 124.4-104.3 -80.7 -7.3 20.9 3.3 27.2 78 78 A G S < S+ 0 0 57 -3,-2.2 -2,-0.2 1,-0.3 2,-0.1 0.413 78.3 134.3 98.1 0.3 24.0 1.5 28.4 79 79 A S + 0 0 10 30,-0.1 -4,-2.8 31,-0.1 -1,-0.3 -0.473 26.2 167.6 -77.5 164.5 26.0 1.9 25.1 80 80 A S E -M 74 0C 33 -6,-0.2 29,-2.3 -2,-0.1 2,-0.3 -0.986 17.3-174.1-166.2 163.1 29.7 2.9 25.2 81 81 A A E +MO 73 108C 1 -8,-1.8 -8,-2.8 -2,-0.3 2,-0.3 -0.972 9.8 170.8-159.7 152.9 32.8 3.2 23.1 82 82 A S E +MO 72 107C 30 25,-2.4 24,-3.0 -2,-0.3 25,-2.3 -0.985 11.3 124.7-159.6 164.6 36.4 4.1 23.8 83 83 A G E -MO 71 105C 4 -12,-2.2 -12,-1.6 -2,-0.3 22,-0.2 -0.949 48.0 -61.3 174.2-153.4 39.8 4.2 22.2 84 84 A N E -MO 70 104C 20 20,-1.4 20,-1.6 -2,-0.3 2,-0.4 -0.510 43.8-112.8-117.5-173.0 42.9 6.2 21.4 85 85 A V E + O 0 103C 0 -16,-0.5 -19,-2.8 -19,-0.4 2,-0.3 -0.985 26.0 169.0-138.6 143.2 43.5 9.3 19.1 86 86 A F E -MO 65 102C 14 16,-2.3 16,-3.6 -2,-0.4 2,-0.4 -0.940 28.6-128.7-138.1 153.1 45.3 10.3 15.9 87 87 A T E +MO 64 101C 21 -23,-2.4 -23,-2.6 -2,-0.3 2,-0.3 -0.825 41.4 148.1-101.2 150.4 45.2 13.4 13.8 88 88 A D E - O 0 100C 16 12,-2.1 12,-2.3 -2,-0.4 2,-0.4 -0.934 52.2 -69.5-162.5 179.1 44.5 13.1 10.1 89 89 A S E - 0 0 37 -2,-0.3 -65,-2.3 9,-0.2 2,-0.5 -0.737 46.8-173.0 -82.1 129.4 43.0 14.7 7.1 90 90 A V E -IO 23 97C 0 7,-2.4 7,-3.3 -2,-0.4 2,-0.5 -0.991 1.8-169.1-133.0 118.3 39.2 14.7 7.3 91 91 A T E +IO 22 96C 33 -69,-2.5 -69,-2.4 -2,-0.5 2,-0.4 -0.955 8.8 174.3-114.9 126.9 37.0 15.8 4.4 92 92 A V E > S- O 0 95C 0 3,-2.5 3,-2.2 -2,-0.5 -71,-0.1 -0.996 75.3 -12.4-131.3 122.8 33.3 16.5 4.5 93 93 A G T 3 S- 0 0 27 -73,-0.4 -88,-0.4 -2,-0.4 74,-0.1 0.835 129.3 -54.6 58.4 30.5 31.4 17.9 1.5 94 94 A G T 3 S+ 0 0 69 1,-0.2 2,-0.6 -90,-0.1 -1,-0.3 0.456 113.4 119.7 83.6 -4.5 34.7 18.8 -0.2 95 95 A V E < - O 0 92C 6 -3,-2.2 -3,-2.5 -93,-0.1 2,-0.5 -0.872 51.8-152.9 -97.5 119.3 35.9 20.8 2.9 96 96 A T E - O 0 91C 54 -2,-0.6 2,-0.6 -5,-0.2 -5,-0.3 -0.809 10.7-160.7-100.8 129.0 39.1 19.4 4.4 97 97 A A E > - O 0 90C 3 -7,-3.3 -7,-2.4 -2,-0.5 3,-0.7 -0.947 16.5-154.4 -98.5 114.6 40.2 19.7 8.1 98 98 A H E 3 S+ 0 0 147 -2,-0.6 -9,-0.2 1,-0.2 -2,-0.0 -0.736 77.0 15.2 -86.6 145.8 43.9 19.1 8.3 99 99 A G E 3 S+ 0 0 48 -2,-0.3 2,-0.3 1,-0.2 -1,-0.2 0.805 86.6 166.3 68.6 22.5 45.2 17.8 11.6 100 100 A Q E < - O 0 88C 2 -12,-2.3 -12,-2.1 -3,-0.7 2,-0.3 -0.625 41.0-113.8 -73.7 137.1 41.7 16.9 12.7 101 101 A A E - O 0 87C 4 37,-0.4 2,-0.5 -2,-0.3 -14,-0.3 -0.527 30.9-166.8 -71.8 125.6 41.6 14.6 15.8 102 102 A V E - O 0 86C 0 -16,-3.6 -16,-2.3 -2,-0.3 2,-1.0 -0.974 12.6-145.8-116.2 118.9 40.1 11.2 14.9 103 103 A Q E -lO 40 85C 2 -64,-2.8 -62,-2.4 -2,-0.5 2,-0.5 -0.794 18.0-152.1 -90.3 100.6 39.1 9.1 17.9 104 104 A A E -lO 41 84C 0 -20,-1.6 -20,-1.4 -2,-1.0 2,-0.3 -0.642 15.3-122.0 -77.3 130.4 39.9 5.5 16.8 105 105 A A E + O 0 83C 0 -64,-3.0 -60,-0.4 -2,-0.5 -62,-0.4 -0.479 39.1 162.8 -76.5 135.2 37.7 2.9 18.5 106 106 A Q E S+ 0 0 92 -24,-3.0 2,-0.3 1,-0.4 -23,-0.2 0.573 76.7 27.6-112.6 -25.4 39.4 0.1 20.4 107 107 A Q E + O 0 82C 71 -25,-2.3 -25,-2.4 -61,-0.1 -1,-0.4 -1.000 63.9 172.2-140.1 138.2 36.2 -0.9 22.3 108 108 A I E - O 0 81C 6 -2,-0.3 -27,-0.2 -27,-0.2 2,-0.1 -0.995 25.9-124.9-145.6 143.7 32.5 -0.6 21.3 109 109 A S >> - 0 0 21 -29,-2.3 4,-2.2 -2,-0.3 3,-0.8 -0.271 39.0 -89.2 -82.0 171.4 29.4 -2.0 23.0 110 110 A A H 3> S+ 0 0 52 1,-0.2 4,-2.8 2,-0.2 5,-0.2 0.844 120.2 59.0 -50.0 -46.9 26.7 -4.2 21.4 111 111 A Q H 3> S+ 0 0 108 1,-0.2 4,-0.8 2,-0.2 -1,-0.2 0.905 112.3 41.1 -57.1 -36.3 24.5 -1.4 20.1 112 112 A F H X4 S+ 0 0 24 -3,-0.8 3,-0.6 -32,-0.2 -1,-0.2 0.910 112.6 52.6 -78.4 -38.1 27.3 -0.1 18.0 113 113 A Q H 3< S+ 0 0 77 -4,-2.2 -2,-0.2 1,-0.2 -3,-0.2 0.982 109.7 51.6 -56.2 -51.3 28.5 -3.5 16.9 114 114 A Q H 3< S+ 0 0 130 -4,-2.8 2,-1.1 -5,-0.1 -1,-0.2 0.615 92.6 79.0 -59.3 -25.1 25.0 -4.4 15.7 115 115 A D X< + 0 0 33 -4,-0.8 3,-0.6 -3,-0.6 -1,-0.1 -0.770 49.1 170.2 -92.4 100.8 24.5 -1.2 13.6 116 116 A T T 3 + 0 0 80 -2,-1.1 -1,-0.2 1,-0.2 -2,-0.1 0.373 61.7 86.3 -85.8 2.5 26.4 -1.9 10.3 117 117 A N T 3 S+ 0 0 78 -63,-0.1 2,-0.3 -3,-0.1 -1,-0.2 0.736 93.3 35.9 -74.8 -23.1 24.8 1.2 8.8 118 118 A N < - 0 0 4 -3,-0.6 -88,-0.2 -6,-0.2 3,-0.1 -0.858 58.8-151.5-129.9 161.3 27.5 3.6 10.2 119 119 A D S S- 0 0 6 -90,-2.9 -77,-2.3 1,-0.3 2,-0.3 -0.109 75.8 -50.3-112.0 19.5 31.2 3.4 10.8 120 120 A G E - K 0 41C 0 -91,-0.3 -89,-2.3 -79,-0.3 -1,-0.3 -0.811 66.8 -73.5 138.4-172.5 31.1 5.9 13.7 121 121 A L E -jK 31 40C 9 -81,-1.7 -81,-1.9 -2,-0.3 2,-0.5 -0.934 21.7-150.7-128.7 142.1 29.9 9.4 14.7 122 122 A L E -jK 32 39C 0 -91,-1.8 -89,-2.9 -2,-0.3 2,-0.3 -0.971 25.6-141.0-115.7 112.8 31.0 12.9 13.6 123 123 A G E +j 33 0C 1 -85,-1.4 17,-0.5 -2,-0.5 18,-0.5 -0.555 27.9 173.3 -82.0 142.6 30.3 15.4 16.4 124 124 A L + 0 0 1 -91,-2.4 -90,-0.2 -88,-0.5 -87,-0.2 0.153 47.0 107.1-131.1 13.0 29.0 18.9 15.7 125 125 A A S S- 0 0 3 -89,-2.9 65,-0.2 -92,-0.6 14,-0.2 -0.189 88.5 -62.1 -78.2-179.7 28.3 20.1 19.3 126 126 A F > - 0 0 23 63,-2.4 3,-1.8 -92,-0.2 -1,-0.2 -0.446 43.6-125.2 -70.3 143.9 30.6 22.6 21.0 127 127 A S G > S+ 0 0 17 1,-0.3 3,-2.4 2,-0.2 -1,-0.1 0.718 99.2 83.0 -62.7 -20.4 34.2 21.5 21.4 128 128 A S G 3 S+ 0 0 88 1,-0.3 -1,-0.3 58,-0.1 8,-0.1 0.663 93.6 48.2 -55.8 -20.7 34.1 22.2 25.2 129 129 A I G < S+ 0 0 50 -3,-1.8 -92,-0.3 60,-0.2 -1,-0.3 0.308 76.1 129.7-107.7 11.1 32.5 18.8 25.6 130 130 A N < - 0 0 13 -3,-2.4 -92,-0.1 7,-0.2 6,-0.1 -0.409 52.9-143.9 -60.5 138.1 34.9 16.7 23.5 131 131 A T + 0 0 39 5,-0.1 -59,-0.2 -2,-0.1 -1,-0.1 0.418 51.1 130.7 -91.5 1.4 35.9 13.7 25.7 132 132 A V - 0 0 3 -61,-0.1 -61,-0.2 5,-0.1 -48,-0.0 -0.316 52.6-116.0 -66.8 133.9 39.6 13.4 24.6 133 133 A Q B S+N 70 0C 112 -63,-3.1 -63,-2.2 1,-0.2 -2,-0.0 -0.933 81.8 10.7-112.3 146.0 42.1 13.1 27.5 134 134 A P S S+ 0 0 89 0, 0.0 2,-0.4 0, 0.0 -1,-0.2 -0.999 138.9 13.5 -87.3 -6.8 44.4 14.6 28.7 135 135 A Q S S- 0 0 127 -4,-0.0 -2,-0.1 0, 0.0 -4,-0.0 -0.995 83.3-123.0-130.3 126.0 43.6 17.6 26.5 136 136 A S - 0 0 71 -2,-0.4 2,-0.2 -6,-0.1 -5,-0.1 -0.209 25.9-137.7 -65.8 155.0 40.3 17.9 24.7 137 137 A Q - 0 0 42 -10,-0.1 2,-0.3 -100,-0.1 -7,-0.2 -0.672 16.7-102.4-112.0 165.9 40.2 18.3 20.9 138 138 A T - 0 0 66 -2,-0.2 -37,-0.4 1,-0.1 -12,-0.1 -0.662 33.8-116.7 -90.4 143.6 38.2 20.4 18.5 139 139 A T > - 0 0 4 -2,-0.3 4,-2.8 -14,-0.2 5,-0.2 -0.265 35.0 -99.9 -65.6 165.3 35.3 19.1 16.4 140 140 A F H > S+ 0 0 0 -17,-0.5 4,-2.1 1,-0.2 5,-0.2 0.894 125.1 49.8 -52.2 -45.1 35.5 19.1 12.6 141 141 A F H > S+ 0 0 5 -18,-0.5 4,-2.0 2,-0.2 -1,-0.2 0.937 110.6 47.4 -63.4 -47.8 33.4 22.2 12.5 142 142 A D H 4 S+ 0 0 36 1,-0.2 4,-0.4 2,-0.2 -2,-0.2 0.887 110.5 54.5 -63.5 -33.8 35.5 24.1 15.0 143 143 A T H < S+ 0 0 43 -4,-2.8 -1,-0.2 1,-0.2 -2,-0.2 0.917 121.3 28.0 -62.9 -43.5 38.6 23.0 13.2 144 144 A V H >X S+ 0 0 3 -4,-2.1 3,-1.8 -5,-0.2 4,-0.9 0.550 92.0 101.7 -95.8 -8.8 37.4 24.5 9.8 145 145 A K G >< S+ 0 0 66 -4,-2.0 3,-1.0 1,-0.3 -1,-0.2 0.837 81.1 47.6 -49.0 -48.0 35.2 27.2 11.1 146 146 A S G 34 S+ 0 0 116 -4,-0.4 -1,-0.3 1,-0.3 -2,-0.1 0.689 110.1 54.4 -73.3 -14.7 37.5 30.2 10.5 147 147 A S G <4 S+ 0 0 59 -3,-1.8 -145,-2.6 -4,-0.1 -1,-0.3 0.563 91.2 94.2 -86.5 -18.2 38.3 29.0 7.0 148 148 A L B << S-a 2 0A 10 -3,-1.0 -145,-0.2 -4,-0.9 20,-0.1 -0.450 87.2-118.1 -69.9 160.4 34.6 28.8 6.0 149 149 A A S S+ 0 0 63 -147,-2.9 20,-0.1 1,-0.2 -146,-0.1 0.929 106.1 11.7 -65.2 -37.9 32.9 31.8 4.2 150 150 A Q S S- 0 0 92 18,-0.6 2,-2.2 -148,-0.3 -1,-0.2 -0.993 85.6-118.6-138.1 141.0 30.6 32.0 7.3 151 151 A P S S+ 0 0 47 0, 0.0 161,-2.2 0, 0.0 162,-0.3 -0.416 80.5 86.6 -80.7 67.1 31.2 30.1 10.6 152 152 A L E -C 311 0B 5 -2,-2.2 16,-2.8 159,-0.2 2,-0.3 -0.958 55.0-153.7-153.1 164.0 28.0 28.1 10.5 153 153 A F E -CD 310 167B 0 157,-2.1 157,-3.4 -2,-0.3 2,-0.3 -0.928 12.8-159.8-136.7 165.0 26.5 24.9 9.2 154 154 A A E -CD 309 166B 0 12,-2.4 12,-2.8 -2,-0.3 2,-0.4 -0.987 4.7-148.1-146.2 156.7 22.8 24.1 8.4 155 155 A V E -CD 308 165B 1 153,-2.5 153,-1.9 -2,-0.3 2,-0.5 -0.977 16.6-175.1-140.9 137.1 20.9 20.9 8.0 156 156 A A E - D 0 164B 0 8,-2.6 8,-1.6 -2,-0.4 2,-0.4 -0.954 14.5-177.2-122.7 106.3 18.0 19.5 6.1 157 157 A L - 0 0 1 149,-0.5 2,-0.3 -2,-0.5 149,-0.1 -0.879 14.0-165.5 -97.4 141.2 17.0 16.0 7.2 158 158 A K - 0 0 42 3,-0.5 2,-0.8 -2,-0.4 3,-0.3 -0.798 27.0-101.1-129.4 162.1 14.2 14.5 5.2 159 159 A H S S- 0 0 89 -2,-0.3 -145,-0.0 1,-0.2 142,-0.0 -0.760 98.9 -25.2 -85.9 114.7 11.8 11.6 5.4 160 160 A Q S S+ 0 0 99 -2,-0.8 -1,-0.2 -149,-0.2 -148,-0.0 0.820 120.8 89.7 51.2 40.0 13.0 8.8 3.1 161 161 A Q S S- 0 0 105 -3,-0.3 -3,-0.5 -153,-0.0 -1,-0.1 -0.976 85.5 -88.4-153.0 161.3 15.0 11.1 0.8 162 162 A P - 0 0 79 0, 0.0 -153,-0.2 0, 0.0 2,-0.2 -0.383 46.2-176.7 -73.6 153.2 18.5 12.4 0.8 163 163 A G E -B 8 0B 2 -155,-2.3 -155,-1.6 -5,-0.1 2,-0.4 -0.476 14.5-113.2-131.9-168.8 19.2 15.7 2.7 164 164 A V E -BD 7 156B 18 -8,-1.6 -8,-2.6 -157,-0.3 2,-0.5 -0.974 10.1-153.3-137.1 154.3 22.1 18.0 3.2 165 165 A Y E -BD 6 155B 2 -159,-2.7 -159,-3.3 -2,-0.4 2,-0.6 -0.995 28.3-157.0-111.7 113.4 24.5 19.4 5.7 166 166 A D E -BD 5 154B 0 -12,-2.8 -12,-2.4 -2,-0.5 2,-0.5 -0.853 6.5-161.5 -93.3 122.2 25.5 22.8 4.3 167 167 A F E -BD 4 153B 0 -163,-3.1 -163,-2.2 -2,-0.6 -14,-0.2 -0.936 68.3 -0.6-107.5 125.4 28.9 24.0 5.7 168 168 A G S S+ 0 0 1 -16,-2.8 -18,-0.6 -2,-0.5 2,-0.3 0.374 121.6 51.3 86.1 0.5 29.8 27.6 5.5 169 169 A F S S- 0 0 61 -165,-0.2 2,-0.4 -17,-0.1 -15,-0.1 -0.979 74.3-116.4-162.3 161.0 26.7 29.0 3.8 170 170 A I - 0 0 41 -2,-0.3 2,-0.9 -17,-0.1 3,-0.1 -0.888 16.8-149.8-102.4 127.6 22.9 29.0 4.0 171 171 A D > - 0 0 36 -2,-0.4 3,-1.8 1,-0.1 4,-0.1 -0.864 10.8-171.4 -98.5 96.5 20.8 27.5 1.2 172 172 A S G > S+ 0 0 73 -2,-0.9 3,-1.1 1,-0.3 -1,-0.1 0.643 78.9 71.2 -65.0 -14.2 17.6 29.5 1.2 173 173 A S G 3 S+ 0 0 84 1,-0.2 -1,-0.3 -3,-0.1 -2,-0.0 0.531 85.1 71.4 -75.2 -7.6 15.9 27.2 -1.3 174 174 A K G < S+ 0 0 42 -3,-1.8 149,-2.4 148,-0.1 2,-0.3 0.419 102.2 37.1 -88.3 0.7 15.8 24.6 1.5 175 175 A Y B < S-Q 322 0E 26 -3,-1.1 2,-0.4 147,-0.3 147,-0.2 -0.961 77.2-115.2-148.3 161.4 13.1 26.5 3.5 176 176 A T S S- 0 0 87 145,-2.2 2,-0.1 -2,-0.3 -3,-0.1 -0.838 78.9 -11.3 -94.2 138.2 9.9 28.5 3.0 177 177 A G S S- 0 0 60 -2,-0.4 2,-0.3 143,-0.1 -2,-0.1 -0.368 104.5 -36.2 73.4-167.4 9.9 32.1 4.1 178 178 A S - 0 0 105 1,-0.1 -2,-0.1 -2,-0.1 2,-0.1 -0.758 62.0-104.2 -96.5 152.8 12.6 33.7 6.2 179 179 A L - 0 0 30 -2,-0.3 2,-0.5 141,-0.1 141,-0.2 -0.384 24.4-147.7 -70.9 146.1 14.6 32.2 9.1 180 180 A T E -E 319 0B 44 139,-2.1 139,-2.4 -2,-0.1 2,-0.3 -0.990 16.8-148.7-114.7 126.9 13.8 33.1 12.6 181 181 A Y E -E 318 0B 75 -2,-0.5 2,-0.3 137,-0.2 137,-0.2 -0.684 14.7-176.4 -95.2 152.2 16.8 33.2 15.0 182 182 A T E -E 317 0B 14 135,-2.2 135,-2.2 -2,-0.3 2,-0.1 -0.969 33.1 -96.8-143.7 149.0 17.0 32.4 18.7 183 183 A G E -E 316 0B 52 -2,-0.3 11,-0.4 133,-0.2 2,-0.4 -0.435 32.3-140.9 -69.9 145.4 19.8 32.5 21.2 184 184 A V - 0 0 20 131,-2.0 2,-0.7 -2,-0.1 9,-0.2 -0.860 2.1-150.4-105.6 136.2 21.8 29.5 22.0 185 185 A D B +R 192 0F 88 7,-2.3 7,-0.8 -2,-0.4 3,-0.4 -0.928 17.6 176.4-102.2 105.5 23.1 28.6 25.5 186 186 A N > + 0 0 68 -2,-0.7 3,-2.5 1,-0.2 -1,-0.1 0.218 44.1 113.8 -93.4 14.2 26.3 26.6 25.0 187 187 A S T 3 S+ 0 0 84 1,-0.3 -1,-0.2 2,-0.1 -2,-0.0 0.649 85.2 39.3 -61.8 -23.8 27.2 26.2 28.7 188 188 A Q T 3 S- 0 0 140 -3,-0.4 -1,-0.3 2,-0.2 3,-0.1 0.104 122.2-105.0-105.5 16.5 26.7 22.5 28.5 189 189 A G S < S+ 0 0 0 -3,-2.5 -63,-2.4 1,-0.2 2,-0.2 0.491 84.7 116.7 79.3 0.1 28.3 22.2 25.1 190 190 A F S S- 0 0 52 -5,-0.3 2,-1.9 -65,-0.2 -1,-0.2 -0.616 80.2-110.6-100.9 162.1 24.9 21.8 23.3 191 191 A W + 0 0 3 -157,-0.4 21,-2.4 21,-0.4 2,-0.4 -0.621 59.0 173.7 -82.6 73.4 23.0 23.8 20.8 192 192 A S E +RS 185 211F 18 -2,-1.9 -7,-2.3 -7,-0.8 2,-0.3 -0.728 7.3 170.3 -91.9 137.7 20.4 24.5 23.5 193 193 A F E - S 0 210F 2 17,-2.8 17,-2.4 -2,-0.4 2,-0.4 -0.879 28.5-111.4-143.9 162.5 17.5 26.9 23.0 194 194 A N E - S 0 209F 100 -11,-0.4 2,-0.4 -2,-0.3 67,-0.3 -0.852 16.7-158.6-100.5 141.9 14.4 28.1 24.7 195 195 A V E - S 0 208F 5 13,-3.0 13,-1.2 -2,-0.4 65,-0.2 -0.945 8.5-153.1-113.8 138.1 10.8 27.5 23.6 196 196 A D E S- 0 0 106 63,-2.9 11,-1.0 -2,-0.4 2,-0.3 0.740 71.9 -19.5 -80.1 -25.8 8.1 29.8 24.9 197 197 A S E -TS 259 206F 43 62,-0.6 62,-2.3 9,-0.2 2,-0.3 -0.953 58.3-140.3-168.4 166.1 5.2 27.3 24.7 198 198 A Y E -TS 258 205F 17 7,-1.7 7,-2.2 -2,-0.3 2,-0.4 -0.951 2.5-152.4-134.7 162.4 4.2 24.1 23.0 199 199 A T E -TS 257 204F 54 58,-2.6 58,-2.4 -2,-0.3 2,-0.8 -0.964 7.1-172.2-136.1 113.9 1.0 22.8 21.5 200 200 A A E > -TS 256 203F 0 3,-3.4 3,-2.1 -2,-0.4 2,-0.3 -0.885 64.2 -66.0-104.8 96.2 0.4 19.1 21.5 201 201 A G T 3 S- 0 0 25 54,-2.4 28,-0.1 -2,-0.8 56,-0.0 -0.407 122.1 -5.5 61.0-120.5 -2.7 18.6 19.4 202 202 A S T 3 S+ 0 0 97 -2,-0.3 2,-0.4 27,-0.1 -1,-0.3 0.337 124.6 78.9 -85.9 -2.6 -5.6 20.1 21.3 203 203 A Q E < -S 200 0F 71 -3,-2.1 -3,-3.4 25,-0.0 2,-0.3 -0.968 55.6-171.1-115.3 134.1 -3.5 20.9 24.4 204 204 A S E +S 199 0F 84 -2,-0.4 2,-0.3 -5,-0.3 -5,-0.2 -0.825 14.6 164.7-116.6 155.0 -1.0 23.8 24.9 205 205 A G E -S 198 0F 22 -7,-2.2 -7,-1.7 -2,-0.3 -2,-0.0 -0.892 35.6 -49.3-157.8-180.0 1.3 24.3 27.8 206 206 A D E -S 197 0F 144 -2,-0.3 -9,-0.2 -9,-0.2 -10,-0.1 -0.196 54.0-106.7 -60.9 154.3 4.4 26.0 29.3 207 207 A G E + 0 0 36 -11,-1.0 2,-0.2 -10,-0.1 -11,-0.2 0.016 37.0 168.5 -71.6 178.3 7.8 26.5 27.6 208 208 A F E -S 195 0F 40 -13,-1.2 -13,-3.0 -11,-0.1 2,-0.3 -0.871 32.2 -92.5-174.4-177.8 11.0 24.8 28.4 209 209 A S E +S 194 0F 36 85,-0.3 87,-2.5 -2,-0.2 2,-0.3 -0.902 39.2 164.2-117.0 163.4 14.5 24.4 26.9 210 210 A G E -Su 193 296F 0 -17,-2.4 -17,-2.8 -2,-0.3 2,-0.4 -0.975 29.6-108.3-162.6 179.3 15.9 21.7 24.6 211 211 A I E -Su 192 297F 7 85,-2.4 87,-2.5 -2,-0.3 2,-0.8 -0.891 22.0-124.4-124.2 138.9 18.8 20.9 22.3 212 212 A A E + u 0 298F 1 -21,-2.4 2,-0.5 -2,-0.4 -21,-0.4 -0.750 42.9 174.4 -78.3 114.1 19.0 20.5 18.5 213 213 A D > + 0 0 13 85,-2.2 3,-1.7 -2,-0.8 87,-0.3 -0.814 27.4 179.2-137.3 93.8 20.3 17.0 18.2 214 214 A T T 3 S+ 0 0 2 -2,-0.5 -197,-0.2 1,-0.3 86,-0.1 0.684 82.3 68.2 -65.8 -18.9 20.7 15.2 14.9 215 215 A G T 3 S+ 0 0 25 -199,-0.1 2,-0.5 84,-0.1 -1,-0.3 0.464 85.5 78.1 -81.4 -5.1 22.1 12.2 16.6 216 216 A T < - 0 0 37 -3,-1.7 84,-3.2 1,-0.1 85,-0.2 -0.930 68.8-151.7-106.5 129.0 18.8 11.3 18.3 217 217 A T S S+ 0 0 25 -2,-0.5 84,-1.2 82,-0.2 -1,-0.1 0.898 72.4 40.7 -64.8 -44.8 16.1 9.6 16.1 218 218 A L S S- 0 0 21 82,-0.2 81,-0.7 81,-0.1 2,-0.7 -0.366 85.8-100.8-104.8 177.9 13.0 10.8 17.9 219 219 A L E -vW 287 298F 0 67,-2.9 69,-2.5 79,-0.2 2,-0.6 -0.926 40.8-160.5 -99.3 113.2 11.5 13.9 19.6 220 220 A L E +vW 288 297F 36 77,-2.1 77,-2.7 -2,-0.7 2,-0.2 -0.882 17.7 165.8-106.7 122.7 12.0 13.4 23.3 221 221 A L E -v 289 0F 1 67,-2.3 69,-2.1 -2,-0.6 70,-0.3 -0.708 44.7 -68.7-128.8 170.3 9.8 15.5 25.7 222 222 A D >> - 0 0 53 -2,-0.2 4,-2.4 67,-0.2 3,-0.9 -0.296 48.8-115.4 -59.9 146.6 8.8 15.6 29.3 223 223 A D H 3> S+ 0 0 83 1,-0.3 4,-2.6 2,-0.2 5,-0.2 0.836 115.2 58.4 -54.2 -35.0 6.6 12.6 30.3 224 224 A S H 3> S+ 0 0 78 1,-0.2 4,-1.8 2,-0.2 -1,-0.3 0.883 108.7 43.6 -64.1 -38.6 3.8 15.0 31.1 225 225 A V H <> S+ 0 0 6 -3,-0.9 4,-2.5 2,-0.2 -2,-0.2 0.877 112.7 52.4 -72.0 -41.7 3.8 16.3 27.5 226 226 A V H X S+ 0 0 2 -4,-2.4 4,-2.8 2,-0.2 5,-0.2 0.924 109.7 50.2 -59.9 -44.8 4.1 12.8 26.0 227 227 A S H X S+ 0 0 58 -4,-2.6 4,-2.0 -5,-0.2 -2,-0.2 0.921 110.3 49.4 -61.7 -42.5 1.1 11.7 28.1 228 228 A Q H < S+ 0 0 35 -4,-1.8 4,-0.5 -5,-0.2 -1,-0.2 0.925 111.6 49.5 -66.5 -33.3 -0.9 14.6 26.9 229 229 A Y H >< S+ 0 0 0 -4,-2.5 3,-1.6 1,-0.2 -2,-0.2 0.969 114.9 41.7 -65.5 -54.7 -0.0 13.9 23.3 230 230 A Y H >< S+ 0 0 9 -4,-2.8 3,-2.0 1,-0.3 6,-0.3 0.733 98.8 73.0 -70.8 -17.2 -0.9 10.2 23.4 231 231 A S T 3< S+ 0 0 86 -4,-2.0 -1,-0.3 1,-0.3 -2,-0.2 0.723 99.9 50.3 -62.8 -23.5 -4.0 10.8 25.4 232 232 A Q T < S+ 0 0 50 -3,-1.6 2,-0.6 -4,-0.5 -1,-0.3 0.299 93.6 86.6 -92.7 1.2 -5.3 12.2 22.1 233 233 A V S X S- 0 0 7 -3,-2.0 3,-1.9 20,-0.1 20,-0.1 -0.920 83.0-124.8-110.1 113.4 -4.2 9.1 20.1 234 234 A S T 3 S+ 0 0 103 -2,-0.6 14,-0.4 1,-0.3 -2,-0.1 -0.272 88.3 1.1 -60.0 131.8 -6.8 6.4 20.0 235 235 A G T 3 S+ 0 0 57 1,-0.2 -1,-0.3 12,-0.1 11,-0.1 0.481 86.0 160.8 76.0 -0.7 -5.5 3.0 21.2 236 236 A A < + 0 0 26 -3,-1.9 2,-0.3 -6,-0.3 -1,-0.2 -0.357 9.0 164.8 -57.0 134.9 -2.0 4.3 22.0 237 237 A Q E -Y 246 0G 130 9,-2.2 9,-2.8 7,-0.1 2,-0.3 -0.988 37.5-102.0-150.9 152.6 -0.0 2.0 24.3 238 238 A Q E -Y 245 0G 132 -2,-0.3 2,-0.4 7,-0.3 7,-0.3 -0.583 28.5-177.6 -81.2 139.8 3.6 1.6 25.4 239 239 A D E >>> -Y 244 0G 28 5,-2.5 5,-2.0 -2,-0.3 4,-1.7 -0.912 10.6-166.4-137.3 102.9 5.6 -1.2 24.0 240 240 A S T 345S+ 0 0 115 -2,-0.4 -1,-0.1 1,-0.3 5,-0.1 0.720 90.4 60.4 -66.6 -20.4 9.2 -1.4 25.4 241 241 A N T 345S+ 0 0 125 1,-0.2 -1,-0.3 3,-0.1 -3,-0.0 0.867 110.8 40.8 -70.7 -38.0 10.2 -3.8 22.7 242 242 A A T <45S- 0 0 16 -3,-0.8 -2,-0.2 2,-0.2 -1,-0.2 0.723 123.3 -97.7 -80.6 -32.2 9.4 -1.1 20.1 243 243 A G T <5S- 0 0 48 -4,-1.7 2,-0.4 1,-0.2 -3,-0.2 0.503 75.6 -49.0 127.9 0.2 10.8 1.9 21.9 244 244 A G E - 0 0 100 -14,-0.4 3,-2.3 -2,-0.3 34,-0.1 -0.432 49.2-126.0 -60.4 138.0 -2.3 1.5 14.7 249 249 A a T 3 S+ 0 0 60 32,-0.4 -1,-0.1 1,-0.3 33,-0.1 0.675 106.4 58.3 -62.8 -22.4 -0.5 2.7 11.6 250 250 A S T 3 S+ 0 0 104 2,-0.1 -1,-0.3 33,-0.0 -2,-0.1 0.392 78.4 127.7 -85.8 -1.1 -3.6 4.2 10.1 251 251 A T < - 0 0 30 -3,-2.3 2,-0.9 1,-0.1 -4,-0.0 -0.304 63.1-126.6 -59.0 143.0 -4.2 6.5 13.1 252 252 A N - 0 0 157 18,-0.0 -18,-0.2 0, 0.0 -1,-0.1 -0.805 32.9-153.8 -91.3 105.1 -4.6 10.2 12.4 253 253 A L - 0 0 22 -2,-0.9 16,-0.3 1,-0.1 17,-0.1 -0.552 11.0-118.3 -86.2 142.2 -2.0 11.8 14.6 254 254 A P - 0 0 25 0, 0.0 18,-0.1 0, 0.0 2,-0.1 -0.274 32.2-108.3 -69.1 159.2 -2.2 15.3 16.0 255 255 A D - 0 0 85 13,-0.1 -54,-2.4 14,-0.1 2,-0.4 -0.407 26.4-150.1 -78.1 165.4 0.4 17.9 15.1 256 256 A F E +TX 200 267F 0 11,-2.4 11,-3.7 -56,-0.2 2,-0.3 -0.999 20.3 171.4-135.4 135.6 2.9 19.1 17.6 257 257 A S E -TX 199 266F 15 -58,-2.4 -58,-2.6 -2,-0.4 2,-0.3 -0.976 18.3-156.7-140.6 162.2 4.5 22.5 17.6 258 258 A V E -TX 198 265F 2 7,-1.8 7,-2.6 -2,-0.3 2,-0.6 -0.972 20.5-128.2-134.7 148.7 6.7 24.8 19.7 259 259 A S E -TX 197 264F 26 -62,-2.3 -63,-2.9 -2,-0.3 -62,-0.6 -0.887 27.6-177.9 -98.3 121.6 7.0 28.6 19.7 260 260 A I E > - X 0 263F 0 3,-3.3 3,-2.5 -2,-0.6 -65,-0.1 -0.959 69.8 -31.2-124.7 111.0 10.6 29.8 19.4 261 261 A S T 3 S- 0 0 59 -2,-0.5 -1,-0.1 1,-0.3 -80,-0.1 0.866 127.3 -45.5 49.1 39.6 11.4 33.5 19.4 262 262 A G T 3 S+ 0 0 67 1,-0.3 2,-0.4 -82,-0.1 -1,-0.3 0.360 117.5 111.8 88.4 -8.2 7.9 34.2 17.9 263 263 A Y E < -X 260 0F 28 -3,-2.5 -3,-3.3 -82,-0.1 2,-0.7 -0.848 61.7-138.2-100.8 134.0 8.2 31.4 15.2 264 264 A T E -X 259 0F 80 -2,-0.4 2,-0.8 -5,-0.2 -5,-0.2 -0.864 12.1-161.7 -93.5 113.3 6.0 28.4 15.3 265 265 A A E -X 258 0F 0 -7,-2.6 -7,-1.8 -2,-0.7 2,-0.5 -0.835 15.3-166.5 -92.8 108.4 7.9 25.2 14.4 266 266 A T E -X 257 0F 52 -2,-0.8 -9,-0.3 -9,-0.2 -2,-0.0 -0.861 17.9-161.7-103.9 127.2 5.2 22.6 13.5 267 267 A V E -X 256 0F 0 -11,-3.7 -11,-2.4 -2,-0.5 35,-0.1 -0.922 28.1-133.5 -98.3 112.7 5.8 18.9 13.2 268 268 A P >> - 0 0 46 0, 0.0 3,-1.8 0, 0.0 4,-0.8 -0.340 18.2-115.4 -64.7 147.7 2.9 17.6 11.2 269 269 A G H >> S+ 0 0 4 1,-0.3 3,-1.0 -16,-0.3 4,-0.6 0.814 112.9 67.9 -52.9 -32.1 1.2 14.5 12.6 270 270 A S H >4 S+ 0 0 97 1,-0.3 3,-0.7 2,-0.2 -1,-0.3 0.849 100.5 48.5 -56.1 -36.0 2.3 12.6 9.4 271 271 A L H <4 S+ 0 0 28 -3,-1.8 -1,-0.3 1,-0.2 -2,-0.2 0.649 99.3 67.6 -81.7 -13.2 5.9 12.9 10.6 272 272 A I H << S+ 0 0 0 -3,-1.0 14,-2.5 -4,-0.8 2,-1.1 0.573 79.3 84.7 -82.2 -9.4 5.0 11.7 14.1 273 273 A N E << -A 285 0G 42 -3,-0.7 12,-0.2 -4,-0.6 -1,-0.1 -0.834 64.6-174.1 -89.8 97.7 4.3 8.3 12.6 274 274 A Y E - 0 0 28 10,-2.2 -1,-0.2 -2,-1.1 11,-0.1 0.916 41.6-103.6 -59.2 -47.2 7.9 7.0 12.7 275 275 A G E -A 284 0G 7 9,-0.8 9,-2.9 -3,-0.2 -1,-0.3 -0.904 67.8 -5.2 149.3-169.5 7.0 3.8 10.9 276 276 A P E -A 283 0G 79 0, 0.0 7,-0.3 0, 0.0 5,-0.1 -0.191 57.5-138.6 -53.6 135.8 6.5 0.1 11.7 277 277 A S - 0 0 14 5,-2.6 6,-0.1 3,-0.2 4,-0.1 0.690 26.3-128.5 -74.1 -20.6 7.3 -0.6 15.3 278 278 A G S S+ 0 0 74 2,-0.4 2,-0.3 4,-0.4 3,-0.1 0.707 88.6 91.9 78.5 18.8 9.1 -3.8 14.5 279 279 A D S S- 0 0 62 1,-0.4 3,-0.3 3,-0.3 -2,-0.1 -0.775 104.4 -61.8-146.3 85.0 6.9 -5.6 17.1 280 280 A G S S- 0 0 68 -2,-0.3 2,-0.6 1,-0.2 -1,-0.4 -0.273 99.5 -23.5 69.9-152.8 3.9 -6.9 15.2 281 281 A S S S+ 0 0 113 -3,-0.1 -32,-0.4 -4,-0.1 2,-0.2 -0.361 101.5 92.7 -98.4 55.5 1.4 -4.7 13.4 282 282 A T - 0 0 26 -2,-0.6 -5,-2.6 -3,-0.3 -4,-0.4 -0.756 63.6-121.8-133.3 171.0 1.7 -1.3 15.0 283 283 A a E -ZA 247 276G 5 -36,-3.1 -36,-2.0 -7,-0.3 2,-0.3 -0.929 24.5-118.2-117.1 146.6 3.6 1.9 14.3 284 284 A L E -ZA 246 275G 10 -9,-2.9 -10,-2.2 -2,-0.4 -9,-0.8 -0.663 26.3-118.9 -87.9 139.5 6.0 3.7 16.6 285 285 A G E - A 0 273G 0 -40,-2.6 -12,-0.2 -2,-0.3 -13,-0.1 -0.513 7.8-143.1 -74.3 141.5 5.3 7.3 17.8 286 286 A G S S+ 0 0 0 -14,-2.5 -67,-2.9 -2,-0.2 2,-0.5 0.600 87.8 71.6 -78.8 -21.0 7.9 9.9 16.9 287 287 A I E +v 219 0F 0 -15,-0.3 2,-0.3 -69,-0.2 -42,-0.2 -0.920 65.9 154.2 -94.9 129.9 7.3 11.6 20.2 288 288 A Q E -v 220 0F 9 -69,-2.5 -67,-2.3 -2,-0.5 -44,-0.1 -0.887 44.6 -66.3-145.1 175.4 8.7 9.7 23.3 289 289 A S E -v 221 0F 34 -2,-0.3 -67,-0.2 -69,-0.2 -69,-0.0 -0.341 19.8-151.5 -66.6 143.0 9.9 10.3 26.8 290 290 A N > - 0 0 7 -69,-2.1 3,-1.5 -2,-0.1 5,-0.2 0.195 47.0-120.4 -90.1 7.8 13.1 12.2 27.6 291 291 A S T 3 - 0 0 98 -70,-0.3 -69,-0.1 1,-0.3 -2,-0.0 0.761 61.2 -57.5 56.0 37.7 13.2 10.0 30.7 292 292 A G T 3 S+ 0 0 58 -71,-0.2 -1,-0.3 1,-0.1 -70,-0.1 0.379 92.7 135.1 82.4 3.7 13.1 12.7 33.3 293 293 A I < - 0 0 82 -3,-1.5 -2,-0.1 2,-0.1 3,-0.1 0.629 65.5-124.3 -66.0 -8.9 16.2 14.8 32.3 294 294 A G S S+ 0 0 57 1,-0.2 2,-0.3 -73,-0.0 -85,-0.3 0.589 82.5 70.6 79.2 9.1 14.5 18.2 32.5 295 295 A F S S- 0 0 60 -5,-0.2 -85,-0.2 -87,-0.1 2,-0.2 -0.974 79.2-112.2-153.2 154.4 15.2 19.3 29.0 296 296 A S E -u 210 0F 1 -87,-2.5 -85,-2.4 -2,-0.3 2,-0.7 -0.603 13.7-138.7 -93.8 150.5 13.9 18.3 25.5 297 297 A I E -uW 211 220F 13 -77,-2.7 -77,-2.1 -2,-0.2 2,-1.9 -0.898 7.6-158.3-110.9 102.3 15.7 16.5 22.7 298 298 A F E +uW 212 219F 0 -87,-2.5 -85,-2.2 -2,-0.7 -79,-0.2 -0.636 34.3 167.4 -81.0 80.3 14.8 18.0 19.3 299 299 A G >> - 0 0 0 -2,-1.9 4,-2.5 -81,-0.7 3,-1.0 0.076 51.6 -62.5 -85.2-167.3 15.9 14.9 17.4 300 300 A D H 3> S+ 0 0 1 -84,-3.2 4,-2.4 -87,-0.3 -82,-0.2 0.816 125.4 62.3 -55.9 -40.0 15.3 13.8 13.8 301 301 A I H 34 S+ 0 0 0 -84,-1.2 -1,-0.3 1,-0.2 4,-0.2 0.892 113.9 37.3 -51.3 -46.9 11.5 13.6 13.9 302 302 A F H X4 S+ 0 0 1 -3,-1.0 3,-1.8 1,-0.2 4,-0.3 0.893 113.8 55.0 -69.6 -46.6 11.4 17.3 14.7 303 303 A L H >< S+ 0 0 2 -4,-2.5 3,-1.7 1,-0.3 -146,-0.5 0.818 93.3 70.0 -61.2 -30.6 14.3 18.3 12.4 304 304 A K T 3< S+ 0 0 13 -4,-2.4 -1,-0.3 1,-0.3 -145,-0.2 0.674 98.5 53.3 -58.9 -19.5 12.7 16.6 9.4 305 305 A S T < S+ 0 0 14 -3,-1.8 17,-2.2 -5,-0.2 2,-0.3 0.613 111.4 44.3 -93.1 -7.0 10.1 19.5 9.5 306 306 A Q E < - F 0 321B 2 -3,-1.7 -149,-0.5 -4,-0.3 2,-0.5 -0.820 68.1-129.3-133.5 160.5 12.6 22.3 9.5 307 307 A Y E - F 0 320B 0 13,-2.6 13,-1.2 -2,-0.3 2,-0.5 -0.964 38.3-161.4-100.5 133.4 15.7 23.7 7.9 308 308 A V E -CF 155 319B 0 -153,-1.9 -153,-2.5 -2,-0.5 2,-0.5 -0.974 12.3-155.8-128.3 124.0 18.0 24.6 10.9 309 309 A V E -CF 154 318B 0 9,-2.6 9,-2.2 -2,-0.5 2,-0.8 -0.892 3.3-159.5 -97.9 125.2 21.0 27.0 10.8 310 310 A F E -CF 153 317B 0 -157,-3.4 -157,-2.1 -2,-0.5 2,-0.6 -0.893 18.9-173.9-105.6 98.0 23.7 26.4 13.6 311 311 A D E > -CF 152 316B 14 5,-2.6 5,-2.4 -2,-0.8 -159,-0.2 -0.875 23.9-160.6-104.2 119.1 25.5 29.7 13.7 312 312 A S T 5S+ 0 0 29 -161,-2.2 2,-0.9 -2,-0.6 -160,-0.1 0.703 74.4 91.4 -68.0 -19.0 28.6 30.0 15.9 313 313 A D T 5S- 0 0 112 -162,-0.3 -2,-0.1 1,-0.2 3,-0.0 -0.689 111.0 -7.6 -78.6 104.7 28.1 33.8 15.8 314 314 A G T 5S- 0 0 69 -2,-0.9 -1,-0.2 1,-0.2 2,-0.2 -0.603 106.3-104.8 141.0 -70.1 26.0 34.5 18.9 315 315 A P T 5S+ 0 0 22 0, 0.0 -131,-2.0 0, 0.0 2,-0.3 0.657 72.7 153.2 -75.0 170.1 25.9 31.6 19.0 316 316 A Q E < -EF 183 311B 50 -5,-2.4 -5,-2.6 -133,-0.2 2,-0.4 -0.978 38.3-130.2-157.9 159.1 22.3 31.2 17.7 317 317 A L E -EF 182 310B 0 -135,-2.2 -135,-2.2 -2,-0.3 2,-0.4 -0.971 17.1-155.1-114.0 137.1 20.0 28.8 15.8 318 318 A G E -EF 181 309B 0 -9,-2.2 -9,-2.6 -2,-0.4 2,-0.4 -0.919 14.1-171.8-110.0 141.6 17.8 29.8 12.8 319 319 A F E +EF 180 308B 0 -139,-2.4 -139,-2.1 -2,-0.4 -11,-0.2 -0.978 15.6 153.2-133.7 146.6 14.6 27.9 11.9 320 320 A A E - F 0 307B 0 -13,-1.2 -13,-2.6 -2,-0.4 -143,-0.1 -0.954 53.6 -78.1-160.1 158.8 12.1 27.9 9.0 321 321 A P E - F 0 306B 51 0, 0.0 -145,-2.2 0, 0.0 -15,-0.3 -0.383 56.3-106.1 -65.1 136.3 9.8 25.2 7.5 322 322 A Q B Q 175 0E 36 -17,-2.2 -147,-0.3 -147,-0.2 -148,-0.1 -0.334 360.0 360.0 -68.5 139.5 11.6 22.8 5.3 323 323 A A 0 0 81 -149,-2.4 -1,-0.0 -3,-0.1 -17,-0.0 -0.991 360.0 360.0-114.7 360.0 11.1 23.2 1.6