==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=25-SEP-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER SPLICING 06-APR-09 2WFH . COMPND 2 MOLECULE: SLIT HOMOLOG 2 PROTEIN C-PRODUCT; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR E.SEIRADAKE,A.C.VON PHILIPSBORN,M.HENRY,M.FRITZ,H.LORTAT-JAC . 362 2 8 8 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 15904.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 219 60.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 50 13.8 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 12 3.3 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 28 7.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 61 16.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 14 3.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 2 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 2 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 727 A a 0 0 96 0, 0.0 25,-0.2 0, 0.0 6,-0.1 0.000 360.0 360.0 360.0 122.2 22.0 -22.5 41.6 2 728 A P > - 0 0 6 0, 0.0 3,-1.9 0, 0.0 23,-0.1 -0.201 360.0-125.7 -53.4 142.4 21.3 -24.4 38.3 3 729 A T T 3 S+ 0 0 131 1,-0.3 22,-0.1 21,-0.3 0, 0.0 0.766 112.3 55.5 -58.4 -26.5 23.9 -27.0 37.3 4 730 A E T 3 S+ 0 0 70 20,-0.2 -1,-0.3 2,-0.0 2,-0.2 0.416 110.5 52.9 -86.8 0.6 24.3 -25.3 34.0 5 731 A b < - 0 0 14 -3,-1.9 2,-0.4 9,-0.1 9,-0.2 -0.738 69.5-128.5-132.5 170.2 25.1 -21.9 35.7 6 732 A T E -A 13 0A 85 7,-2.1 7,-2.8 -2,-0.2 2,-0.4 -0.992 27.0-162.4-121.1 139.2 27.3 -20.1 38.2 7 733 A a E +A 12 0A 51 -2,-0.4 2,-0.3 5,-0.2 5,-0.2 -0.960 15.3 173.0-125.3 135.2 25.7 -17.9 40.8 8 734 A L E > S-A 11 0A 121 3,-2.4 3,-2.5 -2,-0.4 -2,-0.0 -0.923 72.1 -37.6-140.9 118.4 27.1 -15.1 43.0 9 735 A D T 3 S- 0 0 127 -2,-0.3 3,-0.1 1,-0.3 -2,-0.0 0.808 127.1 -33.0 32.2 63.4 24.8 -13.0 45.3 10 736 A T T 3 S+ 0 0 46 1,-0.2 21,-2.7 21,-0.1 22,-1.5 0.255 113.8 112.8 81.8 -5.3 21.8 -12.7 42.8 11 737 A V E < -Ab 8 32A 27 -3,-2.5 -3,-2.4 20,-0.2 2,-0.5 -0.869 46.5-170.4 -96.9 125.4 23.8 -12.7 39.6 12 738 A V E -Ab 7 33A 0 20,-2.6 22,-2.6 -2,-0.5 2,-0.5 -0.967 3.0-168.8-124.2 117.1 23.3 -15.9 37.5 13 739 A R E +Ab 6 34A 41 -7,-2.8 -7,-2.1 -2,-0.5 22,-0.2 -0.948 21.7 158.9-111.3 126.9 25.5 -16.7 34.5 14 740 A b > + 0 0 0 20,-3.0 3,-0.6 -2,-0.5 5,-0.2 -0.272 28.7 157.7-135.8 43.7 24.7 -19.5 32.0 15 741 A S T 3 + 0 0 21 1,-0.2 22,-0.2 2,-0.1 20,-0.1 -0.482 60.5 0.6 -79.0 138.8 26.8 -18.2 29.1 16 742 A N T 3 S+ 0 0 90 20,-2.3 -1,-0.2 -2,-0.2 22,-0.2 0.874 86.5 129.1 56.5 45.5 28.0 -20.3 26.2 17 743 A K S < S- 0 0 101 -3,-0.6 21,-0.1 19,-0.2 -1,-0.1 0.223 75.9-112.7-115.7 11.1 26.4 -23.5 27.6 18 744 A G + 0 0 42 19,-0.6 2,-0.2 1,-0.2 20,-0.1 0.807 59.2 163.8 64.5 31.3 24.5 -24.8 24.5 19 745 A L + 0 0 21 -5,-0.2 20,-3.1 1,-0.1 -1,-0.2 -0.532 29.7 173.0 -84.2 144.9 21.1 -24.2 26.0 20 746 A K S S+ 0 0 126 1,-0.2 21,-0.4 -2,-0.2 2,-0.3 0.407 75.2 37.7-120.5 -6.4 17.8 -24.0 24.2 21 747 A V S S- 0 0 102 19,-0.1 -1,-0.2 20,-0.1 18,-0.1 -0.958 99.5 -85.7-135.7 156.0 15.5 -23.8 27.2 22 748 A L - 0 0 9 -2,-0.3 2,-0.1 1,-0.1 -2,-0.1 -0.333 48.7-109.1 -55.8 139.2 15.9 -22.0 30.5 23 749 A P - 0 0 6 0, 0.0 3,-0.5 0, 0.0 2,-0.2 -0.434 34.9-115.8 -61.0 142.6 17.8 -24.0 33.2 24 750 A K S S+ 0 0 192 1,-0.2 -21,-0.3 -2,-0.1 -20,-0.2 -0.562 91.6 42.7 -76.6 145.0 15.6 -25.3 36.0 25 751 A G + 0 0 53 1,-0.2 -1,-0.2 -2,-0.2 3,-0.0 0.736 62.5 167.7 93.3 26.7 16.3 -23.9 39.5 26 752 A I - 0 0 11 -3,-0.5 -1,-0.2 -25,-0.2 2,-0.1 -0.530 46.2-107.7 -65.8 129.4 16.9 -20.2 38.9 27 753 A P > - 0 0 35 0, 0.0 3,-1.7 0, 0.0 -1,-0.1 -0.404 19.4-126.0 -64.4 147.1 16.8 -18.6 42.4 28 754 A R T 3 S+ 0 0 217 1,-0.3 24,-0.4 -2,-0.1 23,-0.2 0.712 107.3 56.5 -66.5 -20.9 13.7 -16.6 43.0 29 755 A D T 3 S+ 0 0 80 22,-0.1 -1,-0.3 21,-0.1 21,-0.0 0.207 74.9 145.9 -97.2 15.7 15.8 -13.5 44.0 30 756 A V < + 0 0 0 -3,-1.7 22,-0.3 1,-0.1 -19,-0.2 -0.237 19.5 173.5 -58.8 136.5 17.8 -13.3 40.7 31 757 A T + 0 0 35 -21,-2.7 23,-2.4 1,-0.4 24,-1.6 0.661 69.1 32.2-113.9 -35.1 18.6 -9.7 39.6 32 758 A E E -bc 11 55A 53 -22,-1.5 -20,-2.6 22,-0.2 2,-0.5 -0.997 65.2-171.6-130.8 129.8 20.9 -10.3 36.6 33 759 A L E -bc 12 56A 0 22,-2.4 24,-2.5 -2,-0.4 2,-0.7 -0.972 5.0-163.5-128.8 115.3 20.6 -13.2 34.2 34 760 A Y E +bc 13 57A 1 -22,-2.6 -20,-3.0 -2,-0.5 24,-0.1 -0.902 24.7 154.5-105.3 111.0 23.2 -14.0 31.5 35 761 A L + 0 0 0 22,-3.1 3,-0.5 -2,-0.7 5,-0.2 -0.035 28.8 143.5-118.7 22.7 22.0 -16.3 28.8 36 762 A D + 0 0 4 1,-0.2 -20,-2.3 21,-0.2 -19,-0.2 -0.299 57.0 24.9 -67.5 146.3 24.4 -15.1 26.1 37 763 A G S S+ 0 0 14 22,-2.1 -19,-0.6 -22,-0.2 -1,-0.2 0.855 94.8 110.0 73.7 38.6 26.0 -17.4 23.6 38 764 A N S S- 0 0 5 22,-0.5 -1,-0.2 -3,-0.5 -18,-0.2 -0.397 77.8-100.9-122.8-161.0 23.3 -20.2 23.6 39 765 A Q + 0 0 55 -20,-3.1 2,-0.1 -2,-0.2 22,-0.1 -0.153 54.9 153.9-125.6 37.8 20.7 -21.5 21.1 40 766 A F - 0 0 4 -5,-0.2 22,-2.4 1,-0.1 -19,-0.1 -0.458 24.6-170.3 -64.1 138.1 17.5 -19.9 22.5 41 767 A T + 0 0 75 -21,-0.4 23,-1.0 -2,-0.1 24,-0.6 0.496 69.4 20.5-106.7 -10.8 14.9 -19.4 19.8 42 768 A L S S- 0 0 94 -22,-0.2 -1,-0.1 21,-0.2 24,-0.1 -0.939 86.6 -96.6-148.2 161.7 12.4 -17.3 21.8 43 769 A V - 0 0 7 22,-0.4 24,-0.1 -2,-0.3 2,-0.1 -0.834 54.5-115.7 -79.0 116.3 12.4 -15.1 25.0 44 770 A P > - 0 0 18 0, 0.0 3,-1.5 0, 0.0 4,-0.2 -0.326 14.9-146.3 -59.1 129.7 11.1 -17.6 27.6 45 771 A K G > S+ 0 0 103 1,-0.3 3,-1.6 2,-0.1 4,-0.1 0.814 94.1 70.0 -68.8 -24.5 7.7 -16.5 29.0 46 772 A E G > S+ 0 0 100 1,-0.3 3,-1.6 2,-0.2 -1,-0.3 0.569 73.9 84.7 -71.0 -9.7 8.6 -18.0 32.4 47 773 A L G X S+ 0 0 1 -3,-1.5 3,-1.4 1,-0.2 -1,-0.3 0.751 76.9 71.3 -56.1 -25.6 11.2 -15.2 32.9 48 774 A S G < S+ 0 0 28 -3,-1.6 -1,-0.2 1,-0.3 -2,-0.2 0.525 80.4 72.8 -76.5 -3.7 8.3 -13.1 34.2 49 775 A N G < S+ 0 0 112 -3,-1.6 2,-1.1 1,-0.1 -1,-0.3 0.657 79.9 81.8 -72.9 -17.1 8.1 -15.2 37.4 50 776 A Y X - 0 0 38 -3,-1.4 3,-1.4 -4,-0.2 -1,-0.1 -0.746 60.5-177.4-101.1 94.0 11.4 -13.6 38.6 51 777 A K T 3 S+ 0 0 86 -2,-1.1 -1,-0.2 1,-0.3 25,-0.1 0.514 76.7 52.7 -79.2 -6.0 10.2 -10.3 40.1 52 778 A H T 3 S+ 0 0 112 -24,-0.4 2,-0.5 -22,-0.3 -1,-0.3 0.385 76.6 123.3-104.4 3.4 13.6 -8.9 41.0 53 779 A L < + 0 0 1 -3,-1.4 -22,-0.2 -6,-0.2 -21,-0.2 -0.534 21.3 158.3 -75.3 113.3 15.1 -9.4 37.6 54 780 A T + 0 0 39 -23,-2.4 25,-2.6 -2,-0.5 24,-2.4 0.520 62.5 46.5-113.1 -14.1 16.4 -6.0 36.2 55 781 A L E +cd 32 79A 10 -24,-1.6 -22,-2.4 23,-0.2 2,-0.4 -0.986 55.6 177.6-134.0 126.4 19.0 -7.3 33.6 56 782 A I E -cd 33 80A 0 23,-2.0 25,-2.3 -2,-0.4 2,-0.6 -0.996 8.2-167.1-122.5 123.5 18.5 -9.9 31.0 57 783 A D E +cd 34 81A 0 -24,-2.5 -22,-3.1 -2,-0.4 -21,-0.2 -0.946 21.6 157.5-110.4 110.3 21.4 -10.7 28.5 58 784 A L + 0 0 0 23,-2.9 3,-0.4 -2,-0.6 5,-0.2 -0.048 24.6 151.5-117.1 25.7 20.3 -12.9 25.5 59 785 A S + 0 0 1 1,-0.2 -22,-2.1 22,-0.1 -21,-0.4 -0.237 61.1 18.6 -51.7 142.6 23.1 -11.7 23.2 60 786 A N S S+ 0 0 70 23,-2.0 -22,-0.5 -24,-0.2 -1,-0.2 0.932 92.5 121.9 61.6 54.6 24.2 -14.2 20.6 61 787 A N S S- 0 0 10 23,-0.7 -1,-0.2 -3,-0.4 -22,-0.2 -0.514 72.6-102.8-125.7-165.2 21.2 -16.6 20.5 62 788 A R + 0 0 121 -22,-2.4 2,-0.5 -2,-0.2 23,-0.1 -0.134 55.3 154.9-117.9 35.5 18.9 -17.6 17.6 63 789 A I + 0 0 0 -5,-0.2 23,-2.6 1,-0.2 -21,-0.2 -0.524 9.0 166.6 -71.2 116.1 15.9 -15.5 18.5 64 790 A S + 0 0 62 -23,-1.0 24,-0.7 -2,-0.5 2,-0.3 0.580 60.3 31.5-102.9 -15.6 13.9 -14.9 15.3 65 791 A T - 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0 0 39 -3,-2.4 -9,-3.0 -9,-0.2 -1,-0.2 -0.591 55.2-108.8 -79.2 137.5 32.4 -10.8 29.9 352 896 B L B > -Q 341 0G 1 -2,-0.3 4,-1.5 -11,-0.2 -11,-0.3 -0.426 11.5-142.1 -59.7 133.4 30.6 -7.5 29.3 353 897 B L T 4 S+ 0 0 0 -13,-2.0 -1,-0.1 1,-0.2 -12,-0.1 0.921 98.4 57.4 -55.3 -46.0 32.5 -4.2 30.1 354 898 B L T 4 S+ 0 0 12 -14,-0.5 -1,-0.2 1,-0.2 -20,-0.1 0.885 117.8 21.3 -53.8 -52.4 29.3 -2.7 31.4 355 899 B T T 4 S+ 0 0 26 2,-0.1 -1,-0.2 3,-0.0 -2,-0.2 0.617 90.2 106.8-107.0 -14.9 28.2 -5.1 34.1 356 900 B T S < S- 0 0 0 -4,-1.5 5,-0.1 1,-0.1 -8,-0.0 -0.459 82.8-102.0 -66.5 127.6 31.4 -7.0 35.2 357 901 B P > - 0 0 69 0, 0.0 3,-2.3 0, 0.0 4,-0.2 -0.292 19.2-131.8 -57.8 130.5 32.5 -5.7 38.5 358 902 B S G > S+ 0 0 17 1,-0.3 3,-1.7 2,-0.2 -31,-0.1 0.777 104.5 69.1 -45.9 -35.3 35.4 -3.2 38.4 359 903 B K G 3 S+ 0 0 173 1,-0.3 -1,-0.3 3,-0.0 -35,-0.0 0.749 90.3 63.3 -59.5 -21.6 37.2 -5.2 41.2 360 904 B K G < S+ 0 0 90 -3,-2.3 2,-1.1 1,-0.1 -1,-0.3 0.547 79.1 91.0 -80.0 -8.4 37.7 -8.1 38.6 361 905 B F < + 0 0 1 -3,-1.7 2,-0.2 -4,-0.2 -41,-0.2 -0.770 65.1 153.1 -89.2 95.5 39.9 -5.8 36.4 362 906 B T 0 0 92 -2,-1.1 -41,-0.6 -43,-0.5 -40,-0.2 -0.776 360.0 360.0-127.8 164.0 43.3 -6.7 37.9 363 907 B h 0 0 113 -43,-0.3 -2,-0.0 -2,-0.2 -43,-0.0 -0.979 360.0 360.0-123.4 360.0 47.0 -6.9 37.1