==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 01-JUN-09 2WJY . COMPND 2 MOLECULE: REGULATOR OF NONSENSE TRANSCRIPTS 1; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR M.CLERICI,A.MOURAO,I.GUTSCHE,N.H.GEHRING,M.W.HENTZE,A.KULOZI . 773 5 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 36274.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 504 65.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 63 8.2 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 60 7.8 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 5 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 50 6.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 88 11.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 198 25.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 12 1.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 2 2 2 2 1 1 3 2 1 1 1 1 0 0 0 0 1 0 0 0 1 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 3 3 3 2 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 5 1 4 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 2 1 1 0 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 116 A K 0 0 194 0, 0.0 295,-0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 125.2 51.6 32.2 34.1 2 117 A D - 0 0 122 1,-0.2 3,-0.1 295,-0.0 290,-0.0 0.247 360.0 -65.6 -68.1-168.9 51.1 30.4 30.8 3 118 A L - 0 0 56 1,-0.1 -1,-0.2 2,-0.1 294,-0.1 -0.536 65.1 -91.2 -72.6 150.0 53.1 27.5 29.2 4 119 A P > - 0 0 50 0, 0.0 3,-1.7 0, 0.0 -1,-0.1 -0.192 38.5-107.3 -54.8 159.3 56.7 28.3 28.2 5 120 A I T 3 S+ 0 0 158 1,-0.3 23,-0.3 -3,-0.1 -2,-0.1 0.741 119.0 59.6 -65.5 -22.8 57.2 29.5 24.6 6 121 A H T 3 S+ 0 0 33 8,-0.1 -1,-0.3 21,-0.1 2,-0.2 0.236 76.5 133.0 -91.6 12.9 58.7 26.1 23.7 7 122 A A S < S- 0 0 13 -3,-1.7 21,-0.5 1,-0.1 7,-0.2 -0.450 70.5-101.9 -64.6 130.3 55.6 24.2 24.6 8 123 A C > - 0 0 4 5,-2.9 4,-1.2 -2,-0.2 21,-0.3 -0.351 26.5-137.7 -50.9 124.4 54.4 21.6 22.0 9 124 A S T 4 S+ 0 0 42 19,-2.9 -1,-0.2 1,-0.2 20,-0.1 0.613 97.4 46.0 -67.9 -12.2 51.5 23.3 20.2 10 125 A Y T 4 S+ 0 0 3 18,-0.2 -1,-0.2 3,-0.1 19,-0.1 0.914 130.9 3.2 -89.6 -64.0 49.6 20.0 20.3 11 126 A C T 4 S- 0 0 6 2,-0.1 116,-2.9 117,-0.1 -2,-0.1 0.601 92.0-113.3-112.1 -16.0 49.8 18.5 23.8 12 127 A G < + 0 0 10 -4,-1.2 -3,-0.1 1,-0.3 -6,-0.0 0.111 56.2 153.3 108.8 -19.8 51.7 21.0 26.0 13 128 A I + 0 0 10 -6,-0.2 -5,-2.9 1,-0.1 -1,-0.3 -0.104 14.3 176.2 -47.9 136.1 55.0 19.1 26.7 14 129 A H + 0 0 44 -7,-0.2 -1,-0.1 5,-0.1 -8,-0.1 0.024 25.3 135.0-142.1 27.3 57.8 21.6 27.3 15 130 A D > - 0 0 60 1,-0.1 3,-2.7 -9,-0.0 4,-0.4 -0.768 54.8-137.6 -75.7 115.1 60.9 19.6 28.3 16 131 A P G > S+ 0 0 36 0, 0.0 3,-0.6 0, 0.0 40,-0.4 0.701 100.1 60.0 -49.8 -26.4 63.6 21.4 26.2 17 132 A A G 3 S+ 0 0 14 1,-0.2 99,-1.8 42,-0.1 42,-0.0 0.695 106.8 46.3 -73.2 -19.2 65.1 18.0 25.3 18 133 A C G < S+ 0 0 2 -3,-2.7 13,-2.6 97,-0.2 2,-0.3 0.334 94.6 94.2-108.8 1.8 61.9 16.7 23.7 19 134 A V E < -A 30 0A 2 -3,-0.6 37,-0.5 -4,-0.4 2,-0.4 -0.731 47.9-164.8-110.8 151.2 60.9 19.7 21.5 20 135 A V E -AB 29 55A 0 9,-2.9 9,-2.0 -2,-0.3 2,-0.5 -0.997 15.6-141.0-136.6 125.8 61.4 20.7 17.9 21 136 A Y E -AB 28 54A 68 33,-2.2 33,-2.1 -2,-0.4 2,-0.8 -0.781 14.8-140.2 -94.5 120.3 60.8 24.2 16.5 22 137 A C E >> -AB 27 53A 0 5,-3.2 4,-2.7 -2,-0.5 5,-0.8 -0.724 6.7-153.5 -89.8 105.9 59.3 24.3 13.0 23 138 A N T 45S+ 0 0 36 29,-1.4 -1,-0.1 -2,-0.8 30,-0.1 0.747 90.5 42.4 -51.0 -38.7 60.9 27.0 10.9 24 139 A T T 45S+ 0 0 100 28,-0.4 -1,-0.2 1,-0.2 29,-0.1 0.909 122.8 36.5 -75.2 -44.5 58.0 27.7 8.6 25 140 A S T 45S- 0 0 38 -3,-0.3 -2,-0.2 2,-0.2 -1,-0.2 0.661 95.1-139.1 -84.9 -16.8 55.2 27.6 11.2 26 141 A K T <5 + 0 0 152 -4,-2.7 2,-0.3 1,-0.2 -3,-0.2 0.860 63.3 117.6 57.2 40.2 57.2 29.2 13.9 27 142 A K E < -A 22 0A 38 -5,-0.8 -5,-3.2 -7,-0.0 2,-0.3 -0.931 61.7-121.6-134.5 157.0 55.8 26.8 16.4 28 143 A W E -A 21 0A 31 -21,-0.5 -19,-2.9 -2,-0.3 2,-0.3 -0.740 25.1-177.9-102.1 149.1 57.2 24.1 18.7 29 144 A F E -A 20 0A 0 -9,-2.0 -9,-2.9 -2,-0.3 2,-0.2 -0.980 21.1-119.3-143.9 152.5 56.2 20.4 18.8 30 145 A C E -A 19 0A 0 -2,-0.3 11,-1.2 -11,-0.2 10,-1.0 -0.552 13.7-129.1 -98.7 159.8 57.3 17.4 20.9 31 146 A N S S+ 0 0 1 -13,-2.6 2,-0.3 85,-0.4 8,-0.1 0.146 78.1 101.7 -89.0 17.9 58.9 14.1 20.0 32 147 A G - 0 0 0 -14,-0.2 8,-1.0 85,-0.1 -2,-0.1 -0.747 62.7-148.1-100.9 152.3 56.3 12.1 21.8 33 148 A R > + 0 0 172 -2,-0.3 3,-2.4 6,-0.2 -1,-0.1 0.697 28.5 171.4 -92.5 -20.8 53.4 10.2 20.1 34 149 A G T 3 S- 0 0 38 1,-0.3 -1,-0.2 3,-0.1 94,-0.1 -0.264 73.1 -5.6 51.1-117.5 50.7 10.5 22.8 35 150 A N T 3 S+ 0 0 84 94,-0.5 -1,-0.3 -2,-0.1 96,-0.2 0.493 126.6 69.0 -83.6 -8.4 47.4 9.3 21.5 36 151 A T S < S- 0 0 21 -3,-2.4 2,-1.1 2,-0.2 4,-0.1 -0.625 88.0-109.9-112.5 166.6 48.6 8.8 17.9 37 152 A S S S+ 0 0 89 -2,-0.2 2,-0.2 2,-0.1 -3,-0.1 -0.663 95.5 31.1 -98.9 79.1 51.0 6.4 16.2 38 153 A G S S- 0 0 10 -2,-1.1 -2,-0.2 -4,-0.0 71,-0.2 -0.529 97.0 -70.9 141.5 148.2 53.8 8.7 15.4 39 154 A S > - 0 0 1 69,-2.8 4,-1.7 -2,-0.2 -6,-0.2 0.087 36.9-114.6 -64.6 173.1 55.3 11.9 17.0 40 155 A H H > S+ 0 0 3 -10,-1.0 4,-1.3 -8,-1.0 -9,-0.2 0.812 113.4 46.4 -81.2 -33.4 53.8 15.3 17.2 41 156 A I H > S+ 0 0 0 -11,-1.2 4,-3.5 2,-0.2 5,-0.2 0.967 113.4 48.9 -67.2 -53.8 56.5 17.0 15.0 42 157 A V H > S+ 0 0 15 1,-0.3 4,-2.1 2,-0.2 -2,-0.2 0.893 111.3 49.3 -55.1 -45.7 56.3 14.4 12.3 43 158 A N H X S+ 0 0 27 -4,-1.7 4,-1.8 65,-0.2 -1,-0.3 0.892 116.4 44.5 -58.2 -41.9 52.5 14.5 12.2 44 159 A H H X S+ 0 0 0 -4,-1.3 4,-3.3 2,-0.2 5,-0.5 0.957 107.6 55.2 -68.0 -55.0 52.7 18.3 11.9 45 160 A L H X>S+ 0 0 1 -4,-3.5 5,-2.5 1,-0.2 4,-0.7 0.896 110.2 50.2 -47.2 -46.2 55.5 18.4 9.3 46 161 A V H <5S+ 0 0 89 -4,-2.1 3,-0.3 -5,-0.2 -1,-0.2 0.953 118.6 33.6 -55.8 -57.0 53.4 16.2 7.1 47 162 A R H <5S+ 0 0 76 -4,-1.8 -2,-0.2 1,-0.2 -1,-0.2 0.872 121.6 45.6 -78.5 -35.6 50.1 18.2 7.3 48 163 A A H <5S- 0 0 29 -4,-3.3 -1,-0.2 -5,-0.2 -2,-0.2 0.511 110.8-125.2 -80.4 -6.2 51.6 21.7 7.5 49 164 A K T <5 + 0 0 162 -4,-0.7 2,-0.2 -5,-0.5 -3,-0.2 0.924 58.2 140.8 67.1 52.8 53.9 20.6 4.6 50 165 A C < + 0 0 8 -5,-2.5 -1,-0.2 -6,-0.2 3,-0.1 -0.728 34.6 171.0-129.5 171.7 57.3 21.5 6.2 51 166 A K + 0 0 109 -2,-0.2 25,-1.3 1,-0.1 2,-0.4 0.391 50.7 101.2-155.5 -21.5 60.8 20.1 6.5 52 167 A E + 0 0 75 23,-0.1 -29,-1.4 24,-0.1 -28,-0.4 -0.702 46.5 178.9 -94.6 137.1 63.0 22.8 8.2 53 168 A V E -B 22 0A 0 13,-0.4 13,-1.9 -2,-0.4 2,-0.4 -0.979 21.2-166.5-144.2 137.8 63.9 22.4 11.9 54 169 A T E -BC 21 65A 17 -33,-2.1 -33,-2.2 -2,-0.3 11,-0.2 -0.986 21.6-137.4-122.1 138.7 65.8 24.1 14.7 55 170 A L E -B 20 0A 4 9,-2.0 -35,-0.1 -2,-0.4 2,-0.1 -0.502 33.2 -86.4 -89.8 165.5 66.6 22.4 18.1 56 171 A H > - 0 0 19 -37,-0.5 3,-2.0 -40,-0.4 6,-0.4 -0.398 26.6-118.8 -79.0 145.5 66.3 24.1 21.5 57 172 A K T 3 S+ 0 0 145 1,-0.3 6,-0.3 6,-0.1 -1,-0.1 0.878 116.4 45.9 -35.4 -57.2 69.0 26.2 23.2 58 173 A D T 3 S+ 0 0 116 4,-0.1 -1,-0.3 3,-0.1 -2,-0.1 0.047 94.8 123.1 -84.7 26.5 69.2 23.7 26.2 59 174 A G S X S- 0 0 15 -3,-2.0 3,-1.1 1,-0.1 -42,-0.1 -0.497 81.3 -98.5 -94.9 160.4 69.3 20.7 23.9 60 175 A P T 3 S+ 0 0 77 0, 0.0 55,-0.1 0, 0.0 -1,-0.1 0.659 127.9 25.1 -43.3 -24.1 71.8 17.8 23.4 61 176 A L T 3 S- 0 0 83 1,-0.3 2,-0.1 -5,-0.2 -4,-0.1 0.465 111.0-123.3-122.7 -10.4 73.3 19.7 20.5 62 177 A G < - 0 0 19 -3,-1.1 2,-1.4 -6,-0.4 -1,-0.3 -0.436 59.4 -28.0 91.0-171.5 72.4 23.4 21.4 63 178 A E S S+ 0 0 140 -6,-0.3 2,-0.4 -2,-0.1 -7,-0.1 -0.629 86.5 142.6 -83.0 89.5 70.4 25.8 19.2 64 179 A T - 0 0 69 -2,-1.4 -9,-2.0 -8,-0.1 2,-0.5 -0.990 52.4-124.1-135.4 140.8 71.2 24.6 15.7 65 180 A V B -C 54 0A 35 -2,-0.4 2,-0.3 -11,-0.2 -11,-0.2 -0.692 37.7-119.7 -75.9 121.9 69.3 24.3 12.4 66 181 A L + 0 0 6 -13,-1.9 -13,-0.4 -2,-0.5 2,-0.3 -0.520 52.9 145.8 -67.4 124.2 69.5 20.6 11.2 67 182 A E - 0 0 84 -2,-0.3 2,-0.2 -15,-0.1 7,-0.2 -0.980 53.9 -87.8-157.0 155.2 71.2 20.5 7.8 68 183 A C > - 0 0 2 5,-1.6 4,-2.1 -2,-0.3 21,-0.2 -0.489 27.9-141.4 -67.3 130.5 73.5 18.2 5.8 69 184 A Y T 4 S+ 0 0 213 19,-2.5 -1,-0.1 -2,-0.2 20,-0.1 0.781 100.8 50.6 -64.6 -25.9 77.2 19.0 6.5 70 185 A N T 4 S- 0 0 90 18,-0.5 -1,-0.2 3,-0.1 19,-0.1 0.967 134.0 -1.4 -73.6 -57.0 77.8 18.4 2.8 71 186 A C T 4 S- 0 0 78 2,-0.1 -2,-0.2 0, 0.0 3,-0.1 0.525 87.4-116.4-119.6 -12.7 75.2 20.6 1.1 72 187 A G < + 0 0 27 -4,-2.1 2,-0.3 1,-0.3 -3,-0.1 0.712 49.8 167.5 77.7 20.8 73.1 22.3 3.8 73 188 A C - 0 0 38 1,-0.1 -5,-1.6 2,-0.1 -1,-0.3 -0.553 21.0-163.8 -67.5 126.8 69.9 20.6 2.7 74 189 A R + 0 0 95 -2,-0.3 2,-0.7 -7,-0.2 -21,-0.3 0.344 45.7 122.9 -99.3 5.8 67.4 21.2 5.5 75 190 A N >> - 0 0 46 1,-0.2 3,-1.5 -23,-0.1 4,-0.8 -0.604 46.6-160.6 -75.5 114.3 64.9 18.5 4.6 76 191 A V T 34 S+ 0 0 1 -25,-1.3 29,-0.5 -2,-0.7 28,-0.3 0.730 88.2 60.0 -67.3 -27.5 64.4 16.2 7.6 77 192 A F T 34 S+ 0 0 99 1,-0.2 -1,-0.3 27,-0.1 -2,-0.1 0.513 111.3 42.6 -78.9 -5.0 62.9 13.4 5.6 78 193 A L T <4 S+ 0 0 55 -3,-1.5 13,-2.5 13,-0.1 -2,-0.2 0.518 98.9 92.2-112.3 -14.2 66.2 13.3 3.5 79 194 A L < + 0 0 1 -4,-0.8 25,-1.7 11,-0.2 26,-0.4 -0.278 44.2 139.7 -84.1 168.1 68.6 13.7 6.4 80 195 A G E -D 103 0B 0 23,-0.3 9,-3.0 24,-0.1 2,-0.3 -0.899 42.8 -87.1 166.8 164.7 70.3 10.9 8.4 81 196 A F E -DE 102 88B 26 21,-1.5 21,-1.9 -2,-0.3 7,-0.2 -0.747 19.3-166.3-102.0 139.2 73.6 9.8 10.0 82 197 A I E E 0 87B 48 5,-2.2 5,-2.1 -2,-0.3 -2,-0.0 -0.990 360.0 360.0-113.6 134.3 76.6 7.9 8.7 83 198 A P 0 0 138 0, 0.0 3,-0.2 0, 0.0 0, 0.0 -0.311 360.0 360.0 -64.8 360.0 79.0 6.5 11.4 84 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 85 204 A V 0 0 178 0, 0.0 2,-0.3 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 54.2 82.3 10.2 15.3 86 205 A V - 0 0 80 -3,-0.2 2,-0.4 -5,-0.0 -5,-0.0 -0.862 360.0-154.7-126.1 149.9 79.1 10.8 13.3 87 206 A V E -E 82 0B 54 -5,-2.1 -5,-2.2 -2,-0.3 2,-0.6 -0.975 14.6-135.3-128.5 137.8 78.0 12.9 10.3 88 207 A L E +E 81 0B 21 -2,-0.4 -19,-2.5 -7,-0.2 -18,-0.5 -0.815 40.3 160.5 -91.7 117.7 74.5 14.3 9.1 89 208 A L - 0 0 19 -9,-3.0 6,-0.1 -2,-0.6 2,-0.0 -0.991 44.8 -98.4-143.4 145.1 74.0 13.8 5.3 90 209 A C > - 0 0 3 -2,-0.3 5,-2.0 -11,-0.2 6,-0.3 -0.361 33.4-128.3 -55.2 134.3 71.3 13.6 2.6 91 210 A R T 5S+ 0 0 145 -13,-2.5 5,-0.3 1,-0.2 4,-0.2 0.914 91.0 62.6 -51.9 -47.8 70.5 10.0 1.8 92 211 A Q T 5S- 0 0 114 -14,-0.2 -1,-0.2 3,-0.2 -2,-0.0 -0.999 122.3 -15.4-130.9 133.0 71.1 10.9 -1.9 93 212 A P T 5S+ 0 0 78 0, 0.0 6,-0.3 0, 0.0 5,-0.2 -0.983 130.1 57.3 -98.6 2.5 73.6 11.8 -3.1 94 213 A C T 5S+ 0 0 10 1,-0.3 -3,-0.2 5,-0.1 -2,-0.1 0.806 110.5 44.4 -66.2 -35.7 75.6 12.7 0.0 95 214 A A S S- 0 0 16 -5,-0.3 3,-1.8 -6,-0.3 -6,-0.0 -0.372 82.8-127.3 -57.9 133.1 76.2 7.8 -1.7 97 216 A Q T 3 S+ 0 0 182 1,-0.3 -1,-0.1 2,-0.1 -3,-0.1 0.515 99.1 83.1 -64.9 -7.1 79.8 6.7 -1.8 98 217 A S T 3 0 0 101 -5,-0.2 -1,-0.3 0, 0.0 -4,-0.1 0.611 360.0 360.0 -73.6 -14.5 80.3 8.7 -5.0 99 218 A S < 0 0 98 -3,-1.8 -5,-0.1 -6,-0.3 -2,-0.1 0.131 360.0 360.0-152.4 360.0 80.8 11.8 -2.8 100 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 101 229 A W 0 0 100 0, 0.0 -19,-0.2 0, 0.0 -10,-0.0 0.000 360.0 360.0 360.0 148.3 73.2 4.9 7.0 102 230 A Q E -D 81 0B 75 -21,-1.9 -21,-1.5 4,-0.0 2,-0.1 -0.996 360.0-123.8-132.2 132.6 70.5 5.9 9.4 103 231 A P E -D 80 0B 44 0, 0.0 -23,-0.3 0, 0.0 -26,-0.1 -0.440 11.5-144.1 -68.3 142.6 67.3 7.9 8.8 104 232 A L S S+ 0 0 1 -25,-1.7 7,-1.5 -28,-0.3 2,-0.6 0.908 97.6 47.5 -74.7 -45.7 66.8 11.0 11.0 105 233 A I B S+F 110 0C 28 -29,-0.5 2,-0.4 -26,-0.4 5,-0.2 -0.887 81.4 172.4 -89.2 123.0 63.1 10.4 11.2 106 234 A Q - 0 0 80 3,-3.3 3,-0.3 -2,-0.6 -4,-0.0 -0.991 60.7 -0.1-141.5 129.0 62.7 6.7 12.1 107 235 A D S S- 0 0 156 -2,-0.4 -1,-0.2 1,-0.2 3,-0.0 0.958 133.7 -51.7 52.4 53.9 59.5 4.9 13.0 108 236 A R S S+ 0 0 156 -70,-0.1 -69,-2.8 -3,-0.1 2,-0.3 0.717 124.6 61.4 57.6 29.9 57.5 8.1 12.6 109 237 A C S S- 0 0 23 -3,-0.3 -3,-3.3 -71,-0.2 3,-0.1 -0.971 87.4 -73.4-167.0 171.7 59.6 10.3 14.9 110 238 A F B -F 105 0C 3 -2,-0.3 -5,-0.2 -5,-0.2 -6,-0.1 -0.245 62.5 -81.8 -66.5 150.9 63.1 11.8 15.5 111 239 A L >> - 0 0 13 -7,-1.5 4,-2.5 1,-0.1 3,-1.8 -0.302 38.6-131.3 -51.4 130.4 66.1 9.8 16.7 112 240 A S T 34 S+ 0 0 66 1,-0.3 -1,-0.1 2,-0.2 5,-0.1 0.825 104.1 54.6 -58.9 -34.7 65.8 9.4 20.5 113 241 A W T 34 S+ 0 0 137 1,-0.2 -1,-0.3 3,-0.1 3,-0.1 0.368 113.4 40.5 -88.6 5.5 69.4 10.5 21.0 114 242 A L T <4 S+ 0 0 14 -3,-1.8 2,-0.4 1,-0.3 -53,-0.2 0.665 133.7 17.3-108.7 -43.9 69.1 13.8 19.1 115 243 A V S < S- 0 0 2 -4,-2.5 -1,-0.3 -97,-0.1 -97,-0.2 -0.964 90.8-128.9-129.3 114.9 65.6 14.7 20.4 116 244 A K - 0 0 115 -99,-1.8 -85,-0.4 -2,-0.4 -3,-0.1 -0.192 13.9-124.6 -64.2 147.4 64.5 12.8 23.6 117 245 A I - 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0 0 1 169,-2.4 3,-0.1 -2,-0.6 6,-0.1 -0.758 7.8-161.2-113.1 85.5 31.7 12.6 59.1 357 493 A P > - 0 0 2 0, 0.0 3,-1.9 0, 0.0 5,-0.3 -0.174 44.6 -65.4 -59.4 161.3 28.0 12.2 59.9 358 494 A P T 3 S+ 0 0 5 0, 0.0 209,-0.2 0, 0.0 371,-0.1 -0.130 121.4 9.8 -52.9 135.1 26.4 14.5 62.6 359 495 A G T 3 S+ 0 0 13 206,-0.1 207,-2.7 -3,-0.1 208,-0.2 0.546 95.1 112.6 76.7 7.7 27.7 14.1 66.1 360 496 A T S < S- 0 0 1 -3,-1.9 204,-0.3 205,-0.2 203,-0.1 0.446 89.1-104.1 -98.1 0.9 30.6 11.8 65.0 361 497 A G > + 0 0 28 -4,-0.1 4,-2.2 -5,-0.1 5,-0.2 0.828 60.9 155.6 84.7 33.5 33.6 14.1 65.8 362 498 A K H > S+ 0 0 20 -5,-0.3 4,-2.5 2,-0.2 5,-0.2 0.923 75.1 49.5 -50.2 -49.8 34.5 15.1 62.2 363 499 A T H > S+ 0 0 26 1,-0.2 4,-2.2 2,-0.2 -1,-0.2 0.907 112.1 45.5 -66.8 -43.8 36.1 18.3 63.6 364 500 A V H > S+ 0 0 20 2,-0.2 4,-1.9 1,-0.2 -1,-0.2 0.821 113.0 52.0 -62.3 -35.7 38.2 16.6 66.2 365 501 A T H X S+ 0 0 1 -4,-2.2 4,-2.0 2,-0.2 -2,-0.2 0.911 110.3 47.7 -71.4 -39.6 39.2 13.9 63.7 366 502 A S H X S+ 0 0 0 -4,-2.5 4,-2.5 1,-0.2 -2,-0.2 0.914 111.3 50.8 -65.2 -41.1 40.3 16.6 61.2 367 503 A A H X S+ 0 0 0 -4,-2.2 4,-2.2 1,-0.2 -1,-0.2 0.877 109.5 50.8 -65.2 -37.1 42.3 18.4 63.9 368 504 A T H X S+ 0 0 0 -4,-1.9 4,-2.0 2,-0.2 -1,-0.2 0.910 110.7 48.5 -68.8 -42.2 44.1 15.2 64.9 369 505 A I H X S+ 0 0 0 -4,-2.0 4,-3.0 2,-0.2 3,-0.3 0.962 111.5 49.3 -58.5 -52.7 45.1 14.4 61.3 370 506 A V H X S+ 0 0 0 -4,-2.5 4,-2.7 1,-0.3 -2,-0.2 0.892 108.1 56.7 -55.0 -42.0 46.3 18.0 60.8 371 507 A Y H X S+ 0 0 14 -4,-2.2 4,-1.3 2,-0.2 -1,-0.3 0.881 109.7 41.9 -60.3 -43.8 48.3 17.6 64.0 372 508 A H H < S+ 0 0 11 -4,-2.0 4,-0.4 -3,-0.3 -2,-0.2 0.912 113.1 54.1 -72.1 -40.1 50.2 14.5 62.8 373 509 A L H >< S+ 0 0 2 -4,-3.0 3,-1.6 1,-0.2 5,-0.5 0.923 107.1 51.8 -56.7 -42.8 50.7 16.0 59.4 374 510 A A H >< S+ 0 0 11 -4,-2.7 3,-1.1 1,-0.3 -1,-0.2 0.849 104.5 56.7 -66.0 -31.5 52.3 19.1 61.0 375 511 A R T 3< S+ 0 0 154 -4,-1.3 -1,-0.3 1,-0.2 -2,-0.2 0.524 89.3 73.6 -77.9 -3.3 54.7 17.0 63.0 376 512 A Q T < S- 0 0 61 -3,-1.6 -1,-0.2 -4,-0.4 -2,-0.2 0.640 102.9-131.5 -86.0 -15.1 56.0 15.4 59.9 377 513 A G < + 0 0 59 -3,-1.1 -3,-0.1 -4,-0.4 -2,-0.1 0.803 59.3 140.0 83.4 34.1 57.8 18.7 59.3 378 514 A N S S- 0 0 76 -5,-0.5 117,-0.5 1,-0.4 118,-0.2 -0.097 73.1 -89.1 -99.9 40.2 57.0 19.5 55.7 379 515 A G S S- 0 0 48 -5,-0.2 -1,-0.4 115,-0.1 -2,-0.1 -0.213 85.2 -13.1 73.7-179.8 56.4 23.3 56.2 380 516 A P - 0 0 18 0, 0.0 2,-0.3 0, 0.0 116,-0.3 -0.208 67.2-129.8 -54.9 131.6 52.9 24.7 57.1 381 517 A V E -r 476 0H 2 94,-2.6 96,-2.9 113,-0.1 2,-0.5 -0.670 21.6-133.6 -78.7 135.5 50.0 22.4 56.7 382 518 A L E -rs 477 497H 0 114,-2.0 116,-2.6 -2,-0.3 2,-0.4 -0.819 24.5-177.4 -95.3 129.8 47.2 23.9 54.7 383 519 A V E +rs 478 498H 2 94,-2.6 96,-2.2 -2,-0.5 2,-0.3 -0.992 9.4 165.7-129.0 126.0 43.6 23.6 56.0 384 520 A C E +rs 479 499H 0 114,-2.3 116,-2.4 -2,-0.4 96,-0.2 -0.923 16.1 178.3-134.7 163.1 40.5 24.9 54.3 385 521 A A E -r 480 0H 0 94,-0.6 96,-1.7 -2,-0.3 116,-0.2 -0.942 40.4-110.4-152.7 165.1 36.8 24.8 54.2 386 522 A P S S+ 0 0 18 0, 0.0 2,-0.3 0, 0.0 96,-0.1 0.681 94.2 47.6 -76.8 -13.1 34.2 26.5 52.1 387 523 A S S > S- 0 0 31 1,-0.1 4,-2.0 94,-0.0 5,-0.2 -0.901 78.3-121.4-129.1 157.0 32.7 28.8 54.8 388 524 A N H > S+ 0 0 41 -2,-0.3 4,-2.7 1,-0.2 5,-0.2 0.886 110.4 49.8 -62.0 -40.2 34.0 31.1 57.4 389 525 A I H > S+ 0 0 64 1,-0.2 4,-2.7 2,-0.2 5,-0.2 0.916 109.7 51.3 -68.2 -36.9 32.4 29.3 60.4 390 526 A A H > S+ 0 0 5 2,-0.2 4,-1.8 1,-0.2 -1,-0.2 0.902 111.5 47.5 -68.7 -36.1 33.7 25.9 59.3 391 527 A V H X S+ 0 0 2 -4,-2.0 4,-3.3 2,-0.2 -2,-0.2 0.961 112.9 49.7 -63.8 -47.7 37.2 27.3 59.0 392 528 A D H X S+ 0 0 20 -4,-2.7 4,-2.5 1,-0.2 -2,-0.2 0.883 108.9 51.6 -59.7 -40.0 36.8 28.9 62.4 393 529 A Q H X S+ 0 0 40 -4,-2.7 4,-1.6 2,-0.2 -1,-0.2 0.909 114.3 44.2 -63.0 -39.7 35.6 25.7 64.0 394 530 A L H X S+ 0 0 4 -4,-1.8 4,-2.6 -5,-0.2 5,-0.3 0.939 110.8 53.4 -71.0 -45.4 38.5 23.9 62.6 395 531 A T H X S+ 0 0 0 -4,-3.3 4,-1.7 1,-0.2 -2,-0.2 0.906 108.4 51.6 -52.7 -46.8 41.0 26.6 63.6 396 532 A E H X S+ 0 0 80 -4,-2.5 4,-1.1 -5,-0.2 -1,-0.2 0.907 110.6 46.1 -61.2 -45.9 39.8 26.5 67.2 397 533 A K H >< S+ 0 0 73 -4,-1.6 3,-0.8 1,-0.2 4,-0.4 0.939 112.4 50.3 -64.8 -45.7 40.2 22.7 67.5 398 534 A I H ><>S+ 0 0 0 -4,-2.6 3,-1.3 1,-0.3 5,-0.6 0.816 103.9 60.3 -58.0 -33.2 43.6 22.7 66.0 399 535 A H H ><5S+ 0 0 65 -4,-1.7 3,-1.7 1,-0.3 -1,-0.3 0.823 93.8 65.0 -66.3 -33.5 44.7 25.5 68.4 400 536 A Q T <<5S+ 0 0 89 -4,-1.1 -1,-0.3 -3,-0.8 -2,-0.2 0.680 91.0 65.6 -60.2 -21.5 43.9 23.1 71.3 401 537 A T T < 5S- 0 0 2 -3,-1.3 -1,-0.3 -4,-0.4 -2,-0.2 0.645 112.6-116.5 -81.2 -11.8 46.8 20.9 70.1 402 538 A G T < 5 + 0 0 62 -3,-1.7 -3,-0.1 1,-0.3 -2,-0.1 0.310 68.1 136.2 96.7 -8.0 49.4 23.6 70.9 403 539 A L < - 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