==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=22-MAR-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER STRUCTURAL PROTEIN 30-JUL-10 2XN4 . COMPND 2 MOLECULE: KELCH-LIKE PROTEIN 2; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR P.CANNING,V.HOZJAN,C.D.O.COOPER,V.AYINAMPUDI,M.VOLLMAR,A.C.W . 572 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 22119.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 371 64.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 257 44.9 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 14 2.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 18 3.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 2 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 44 7.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 13 2.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 14 2.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 12 2.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 21 2 0 11 22 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 11 11 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 306 A P 0 0 124 0, 0.0 285,-3.1 0, 0.0 2,-0.3 0.000 360.0 360.0 360.0 113.9 -4.2 -2.4 -29.5 2 307 A K E -A 285 0A 87 283,-0.3 21,-0.9 284,-0.1 2,-0.4 -0.730 360.0-156.6-116.0 154.0 -2.9 -3.2 -26.0 3 308 A L E -AB 284 22A 17 281,-2.4 281,-2.8 -2,-0.3 2,-0.6 -0.993 19.1-138.6-124.5 131.6 -2.4 -1.4 -22.7 4 309 A M E -AB 283 21A 1 17,-2.0 17,-2.8 -2,-0.4 2,-0.4 -0.870 21.7-153.8 -90.6 125.9 0.3 -2.6 -20.3 5 310 A V E -AB 282 20A 0 277,-3.4 277,-2.1 -2,-0.6 2,-0.5 -0.866 9.3-166.4-108.8 133.5 -1.2 -2.5 -16.8 6 311 A V E -AB 281 19A 0 13,-3.1 13,-2.3 -2,-0.4 2,-0.5 -0.989 12.1-160.2-127.0 120.7 1.1 -2.2 -13.7 7 312 A V E -AB 280 18A 6 273,-3.0 273,-2.8 -2,-0.5 11,-0.2 -0.922 37.0 -58.2-122.4 119.9 -0.6 -2.9 -10.5 8 313 A G + 0 0 0 9,-2.3 31,-0.2 -2,-0.5 2,-0.2 -0.181 63.3 149.1 57.0-139.9 0.4 -1.9 -6.9 9 314 A G - 0 0 0 29,-2.7 6,-2.4 6,-0.4 2,-0.4 -0.632 51.9 -57.7 108.9-171.2 3.9 -3.0 -5.6 10 315 A Q B -DE 14 277B 27 267,-2.8 267,-2.3 4,-0.2 4,-0.2 -0.944 30.7-179.4-118.7 137.3 6.4 -1.5 -3.2 11 316 A A S S- 0 0 31 2,-2.0 264,-0.2 -2,-0.4 240,-0.2 0.505 92.6 -73.7-119.0 -0.5 7.8 1.9 -3.7 12 317 A P S S+ 0 0 44 0, 0.0 2,-0.1 0, 0.0 264,-0.0 -0.938 137.0 70.2 -91.4 -4.6 9.2 0.9 -1.0 13 318 A K S S- 0 0 87 -3,-0.2 -2,-2.0 1,-0.1 2,-0.3 -0.486 100.6-102.5 -69.9 145.5 5.9 1.4 0.8 14 319 A A B -D 10 0B 11 -4,-0.2 -4,-0.2 -2,-0.1 2,-0.2 -0.581 53.2-163.5 -66.7 128.0 3.2 -1.0 -0.3 15 320 A I - 0 0 32 -6,-2.4 23,-1.8 -2,-0.3 -6,-0.4 -0.706 33.0-148.8-120.8 167.5 0.9 1.0 -2.7 16 321 A R + 0 0 91 -2,-0.2 18,-3.1 21,-0.2 -8,-0.2 0.604 57.0 121.1-105.3 -17.6 -2.5 1.0 -4.3 17 322 A S - 0 0 24 16,-0.2 -9,-2.3 -10,-0.1 2,-0.4 -0.142 40.5-166.1 -60.1 137.9 -1.8 2.8 -7.6 18 323 A V E -BC 7 31A 0 13,-0.6 13,-2.4 -11,-0.2 2,-0.3 -0.999 9.1-176.0-124.3 127.4 -2.5 1.1 -10.9 19 324 A E E -BC 6 30A 2 -13,-2.3 -13,-3.1 -2,-0.4 2,-0.4 -0.936 10.0-155.0-122.6 150.5 -1.0 2.7 -14.1 20 325 A C E -BC 5 29A 2 9,-2.7 9,-2.0 -2,-0.3 2,-0.5 -0.977 9.9-141.1-126.8 136.5 -1.4 1.7 -17.7 21 326 A Y E -BC 4 28A 11 -17,-2.8 -17,-2.0 -2,-0.4 2,-0.7 -0.862 10.6-150.4 -99.8 126.1 1.1 2.4 -20.5 22 327 A D E >> -BC 3 27A 6 5,-2.7 4,-2.1 -2,-0.5 5,-1.2 -0.879 2.7-160.1 -97.2 110.7 -0.5 3.3 -23.9 23 328 A F T 45S+ 0 0 48 -21,-0.9 -1,-0.1 -2,-0.7 -20,-0.1 0.837 88.2 49.4 -63.4 -35.5 1.8 2.1 -26.7 24 329 A K T 45S+ 0 0 93 -22,-0.3 -1,-0.2 1,-0.2 -2,-0.0 0.967 121.5 33.3 -68.4 -50.9 0.3 4.5 -29.4 25 330 A E T 45S- 0 0 108 2,-0.1 -2,-0.2 1,-0.0 -1,-0.2 0.690 100.0-137.1 -77.8 -20.5 0.5 7.6 -27.2 26 331 A E T <5 + 0 0 127 -4,-2.1 2,-0.3 1,-0.2 -3,-0.2 0.935 63.6 108.3 59.7 49.8 3.7 6.5 -25.4 27 332 A R E < -C 22 0A 114 -5,-1.2 -5,-2.7 243,-0.0 2,-0.3 -0.994 62.7-121.6-153.6 157.2 2.4 7.6 -22.1 28 333 A W E -C 21 0A 31 -2,-0.3 2,-0.3 -7,-0.2 -7,-0.2 -0.720 22.6-178.4 -97.6 145.0 1.2 6.4 -18.7 29 334 A H E -C 20 0A 59 -9,-2.0 -9,-2.7 -2,-0.3 2,-0.2 -0.987 26.8-114.9-133.7 155.7 -2.1 7.1 -17.0 30 335 A Q E -C 19 0A 94 -2,-0.3 -11,-0.2 -11,-0.2 2,-0.2 -0.567 29.2-174.5 -75.8 141.5 -3.6 6.1 -13.7 31 336 A V E -C 18 0A 28 -13,-2.4 -13,-0.6 -2,-0.2 43,-0.0 -0.644 50.8 -38.5-118.1-171.2 -6.7 3.9 -13.5 32 337 A A - 0 0 30 -2,-0.2 -1,-0.1 -15,-0.1 42,-0.1 -0.241 68.0-119.8 -53.9 126.1 -8.7 2.8 -10.5 33 338 A E - 0 0 109 1,-0.1 -16,-0.2 -16,-0.1 42,-0.2 -0.174 34.3 -89.7 -61.1 154.9 -6.6 2.1 -7.4 34 339 A L - 0 0 1 -18,-3.1 -1,-0.1 1,-0.1 3,-0.1 -0.230 32.5-117.0 -59.4 151.8 -6.5 -1.3 -5.8 35 340 A P S S+ 0 0 61 0, 0.0 2,-0.3 0, 0.0 -1,-0.1 0.689 96.8 9.5 -58.9 -28.3 -9.0 -1.9 -3.0 36 341 A S S S- 0 0 41 -21,-0.1 2,-0.2 -20,-0.1 -2,-0.1 -0.975 97.3 -77.7-148.2 160.6 -6.0 -2.4 -0.7 37 342 A R + 0 0 121 -2,-0.3 2,-0.4 20,-0.2 -21,-0.2 -0.403 58.4 177.4 -55.1 127.3 -2.3 -1.9 -0.5 38 343 A R + 0 0 4 -23,-1.8 -29,-2.7 -29,-0.2 2,-0.3 -0.939 14.5 151.4-150.1 120.3 -0.9 -4.9 -2.4 39 344 A C B +F 56 0C 2 17,-2.2 17,-2.9 -2,-0.4 240,-0.2 -0.907 61.1 38.3-134.4 167.0 2.6 -5.9 -3.3 40 345 A R S S+ 0 0 48 238,-2.1 47,-2.6 -2,-0.3 48,-0.9 0.764 85.3 142.2 63.5 28.5 4.3 -9.2 -3.9 41 346 A A - 0 0 21 237,-0.6 2,-0.3 45,-0.2 13,-0.2 -0.502 54.4-115.1 -94.2 158.3 1.2 -10.6 -5.6 42 347 A G E -H 53 0D 3 11,-2.9 11,-3.0 47,-0.2 2,-0.3 -0.656 33.4-164.6 -78.5 152.9 0.7 -12.8 -8.6 43 348 A M E +H 52 0D 22 47,-0.3 2,-0.3 -2,-0.3 47,-0.2 -0.943 15.1 160.4-147.9 131.8 -1.0 -11.2 -11.6 44 349 A V E -H 51 0D 9 7,-1.3 7,-2.6 -2,-0.3 2,-0.5 -0.929 35.0-125.4-137.7 158.5 -2.6 -12.6 -14.7 45 350 A Y E +H 50 0D 74 -2,-0.3 2,-0.3 5,-0.2 5,-0.2 -0.944 41.4 162.1-100.8 128.6 -5.0 -11.6 -17.4 46 351 A M E > -H 49 0D 13 3,-2.9 3,-2.1 -2,-0.5 -2,-0.1 -0.963 58.8 -10.5-154.1 128.5 -7.9 -14.0 -17.7 47 352 A A T 3 S- 0 0 80 -2,-0.3 3,-0.1 1,-0.3 -1,-0.0 0.842 128.7 -51.9 52.7 37.8 -11.4 -13.9 -19.3 48 353 A G T 3 S+ 0 0 31 1,-0.2 2,-0.3 21,-0.0 -1,-0.3 0.465 119.7 103.8 80.5 6.0 -11.0 -10.1 -19.8 49 354 A L E < -H 46 0D 41 -3,-2.1 -3,-2.9 20,-0.1 2,-0.6 -0.862 66.3-133.4-122.2 146.8 -10.1 -9.4 -16.1 50 355 A V E -HI 45 68D 0 18,-2.2 18,-3.2 -2,-0.3 2,-0.5 -0.914 26.0-156.6 -97.1 125.4 -6.8 -8.7 -14.4 51 356 A F E -HI 44 67D 0 -7,-2.6 -7,-1.3 -2,-0.6 2,-0.6 -0.916 8.7-160.5-104.8 128.6 -6.5 -10.8 -11.3 52 357 A A E -HI 43 66D 0 14,-3.5 14,-2.0 -2,-0.5 2,-0.6 -0.962 18.9-161.4-109.4 116.7 -4.2 -9.7 -8.4 53 358 A V E -HI 42 65D 0 -11,-3.0 -11,-2.9 -2,-0.6 12,-0.2 -0.880 39.2 -50.9-113.9 114.5 -3.5 -12.8 -6.4 54 359 A G S S+ 0 0 0 10,-2.2 2,-0.3 -2,-0.6 32,-0.2 -0.243 70.5 131.8 66.2-148.6 -2.3 -12.8 -2.8 55 360 A G - 0 0 0 30,-3.2 7,-2.5 7,-0.4 2,-0.4 -0.716 56.8 -52.0 100.2-150.9 0.7 -10.7 -1.7 56 361 A F B -FG 39 61C 6 -17,-2.9 -17,-2.2 -2,-0.3 5,-0.2 -0.994 24.0-160.5-142.0 132.3 1.4 -8.4 1.1 57 362 A N - 0 0 48 3,-2.2 -20,-0.2 -2,-0.4 4,-0.1 0.237 61.8 -89.9-101.1 15.1 -0.5 -5.3 2.3 58 363 A G S S+ 0 0 24 2,-0.2 3,-0.1 -19,-0.1 -20,-0.1 0.143 122.7 35.0 93.4 -20.9 2.3 -3.6 4.3 59 364 A S S S+ 0 0 68 1,-0.4 2,-0.3 478,-0.1 478,-0.1 0.618 119.1 24.8-122.5 -44.0 1.4 -5.5 7.5 60 365 A L S S- 0 0 116 476,-0.1 -3,-2.2 0, 0.0 -1,-0.4 -0.916 70.2-115.4-128.4 151.9 0.1 -8.9 6.7 61 366 A R B -G 56 0C 23 -2,-0.3 2,-0.3 43,-0.2 -5,-0.2 -0.626 45.1-147.4 -78.4 145.8 0.4 -11.6 4.0 62 367 A V - 0 0 16 -7,-2.5 23,-2.0 23,-0.3 -7,-0.4 -0.816 33.3-162.1-124.4 158.4 -3.0 -12.1 2.4 63 368 A R + 0 0 78 -2,-0.3 18,-2.5 21,-0.3 -1,-0.1 0.326 60.4 118.8-113.0 1.8 -5.1 -14.7 0.8 64 369 A T - 0 0 48 16,-0.2 -10,-2.2 -11,-0.1 2,-0.4 -0.297 46.4-161.1 -72.6 156.2 -7.4 -12.2 -0.9 65 370 A V E -IJ 53 78D 0 13,-0.5 13,-2.5 -12,-0.2 2,-0.3 -0.980 5.4-168.3-143.3 122.4 -7.7 -12.0 -4.6 66 371 A D E -IJ 52 77D 8 -14,-2.0 -14,-3.5 -2,-0.4 2,-0.4 -0.862 6.0-152.7-118.0 144.7 -9.1 -9.0 -6.4 67 372 A S E -IJ 51 76D 5 9,-3.3 9,-2.6 -2,-0.3 2,-0.5 -0.959 4.1-147.7-123.6 141.5 -10.1 -8.7 -10.1 68 373 A Y E -IJ 50 75D 6 -18,-3.2 -18,-2.2 -2,-0.4 7,-0.2 -0.924 1.8-157.5-112.8 123.4 -10.2 -5.6 -12.3 69 374 A D E >> - J 0 74D 47 5,-2.5 4,-1.7 -2,-0.5 5,-1.4 -0.898 7.8-164.3 -96.2 106.4 -12.7 -5.1 -15.1 70 375 A P T 45S+ 0 0 32 0, 0.0 -1,-0.1 0, 0.0 -21,-0.1 0.745 86.4 55.5 -69.9 -21.1 -10.9 -2.7 -17.4 71 376 A V T 45S+ 0 0 130 -23,-0.2 -2,-0.0 1,-0.2 -23,-0.0 0.921 119.9 32.0 -74.6 -42.0 -14.1 -1.8 -19.3 72 377 A K T 45S- 0 0 135 2,-0.1 -1,-0.2 0, 0.0 3,-0.1 0.619 101.1-136.3 -79.6 -20.8 -15.8 -0.8 -16.0 73 378 A D T <5 + 0 0 74 -4,-1.7 2,-0.3 1,-0.2 -5,-0.0 0.963 60.4 129.1 57.2 55.8 -12.6 0.4 -14.4 74 379 A Q E < -J 69 0D 78 -5,-1.4 -5,-2.5 -42,-0.1 2,-0.4 -1.000 53.3-141.4-146.8 141.6 -13.5 -1.4 -11.2 75 380 A W E +J 68 0D 24 -2,-0.3 2,-0.3 -7,-0.2 -7,-0.2 -0.838 25.7 168.8-102.7 134.6 -12.0 -3.8 -8.7 76 381 A T E -J 67 0D 65 -9,-2.6 -9,-3.3 -2,-0.4 2,-0.1 -0.985 31.8-105.3-140.2 153.6 -14.1 -6.6 -7.1 77 382 A S E -J 66 0D 91 -2,-0.3 -11,-0.2 -11,-0.2 2,-0.2 -0.425 24.2-168.3 -78.4 149.9 -13.2 -9.6 -5.1 78 383 A V E -J 65 0D 22 -13,-2.5 -13,-0.5 1,-0.2 39,-0.0 -0.637 51.6 -50.4-115.4-179.9 -13.1 -13.2 -6.1 79 384 A A - 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