==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER IMMUNE SYSTEM 06-DEC-04 1Y6K . COMPND 2 MOLECULE: INTERLEUKIN-10; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR S.I.YOON,B.C.JONES,K.JOSEPSON,N.J.LOGSDON,M.R.WALTER . 350 2 4 4 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 22195.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 234 66.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 5 1.4 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 70 20.0 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 3 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 26 7.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 38 10.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 89 25.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 3 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 0 0 3 0 0 1 1 0 1 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 2 1 2 2 2 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 1 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 12 L a 0 0 90 0, 0.0 97,-0.0 0, 0.0 96,-0.0 0.000 360.0 360.0 360.0 127.1 14.7 -7.3 13.1 2 13 L T - 0 0 103 95,-0.0 95,-0.1 0, 0.0 0, 0.0 -0.346 360.0 -84.9-112.7 47.9 12.5 -10.0 14.8 3 14 L H - 0 0 152 1,-0.2 94,-0.1 2,-0.1 0, 0.0 0.360 66.4-102.1 65.8 -7.9 9.3 -8.8 13.2 4 15 L F - 0 0 18 1,-0.1 -1,-0.2 2,-0.1 4,-0.1 0.994 40.0-162.2 53.4 73.6 9.4 -6.5 16.2 5 16 L P S S- 0 0 100 0, 0.0 -1,-0.1 0, 0.0 -2,-0.1 0.847 73.1 -56.1 -52.1 -31.3 6.9 -8.3 18.3 6 17 L G S S+ 0 0 45 2,-0.0 4,-0.2 3,-0.0 -2,-0.1 0.256 91.3 134.1 149.0 66.3 6.7 -5.1 20.2 7 18 L N + 0 0 64 2,-0.1 4,-0.3 1,-0.1 -3,-0.0 0.361 59.1 84.9-109.1 -1.5 10.1 -3.9 21.5 8 19 L L S >> S+ 0 0 26 1,-0.2 3,-2.3 2,-0.2 4,-1.1 0.898 74.3 65.0 -69.6 -44.7 9.5 -0.4 20.2 9 20 L P H >> S+ 0 0 11 0, 0.0 4,-2.7 0, 0.0 3,-1.8 0.922 96.7 56.9 -44.5 -55.1 7.5 1.1 23.2 10 21 L N H 3> S+ 0 0 87 1,-0.3 4,-1.1 2,-0.2 -2,-0.2 0.738 106.7 53.9 -48.9 -23.9 10.4 0.7 25.5 11 22 L M H <> S+ 0 0 14 -3,-2.3 4,-1.2 -4,-0.3 -1,-0.3 0.765 106.7 47.4 -84.7 -28.3 12.2 2.9 23.0 12 23 L L H < S+ 0 0 12 -4,-1.0 3,-0.5 -5,-0.3 -1,-0.3 0.897 111.0 49.7 -74.7 -41.4 15.2 11.7 27.8 19 30 L F H >X S+ 0 0 70 -4,-2.1 3,-2.8 1,-0.2 4,-1.1 0.886 99.2 63.4 -64.8 -41.6 13.0 14.6 26.9 20 31 L S H 3X S+ 0 0 57 -4,-3.1 4,-0.6 1,-0.3 3,-0.3 0.830 93.0 67.3 -52.4 -31.3 11.7 15.2 30.4 21 32 L R H << S+ 0 0 180 -4,-0.6 -1,-0.3 -3,-0.5 -2,-0.2 0.573 117.2 22.6 -65.6 -11.0 15.3 15.9 31.3 22 33 L V H <> S+ 0 0 4 -3,-2.8 4,-1.8 -4,-0.1 5,-0.3 0.308 94.9 103.1-136.0 2.6 15.1 19.1 29.2 23 34 L K H X S+ 0 0 21 -4,-1.1 4,-2.2 -3,-0.3 5,-0.2 0.928 84.9 42.3 -54.5 -53.6 11.4 19.7 29.1 24 35 L T H X S+ 0 0 64 -4,-0.6 4,-1.8 2,-0.2 5,-0.3 0.887 108.7 58.3 -65.3 -41.7 11.3 22.5 31.7 25 36 L F H > S+ 0 0 63 1,-0.2 4,-1.5 2,-0.2 3,-0.3 0.961 117.8 30.8 -52.3 -58.3 14.4 24.4 30.4 26 37 L F H X S+ 0 0 62 -4,-1.8 4,-3.2 1,-0.2 -1,-0.2 0.814 117.7 55.8 -74.0 -31.9 13.0 24.9 26.9 27 38 L Q H < S+ 0 0 14 -4,-2.2 -1,-0.2 -5,-0.3 -2,-0.2 0.715 111.8 44.0 -75.8 -17.3 9.4 25.1 27.9 28 39 L M H < S+ 0 0 93 -4,-1.8 -1,-0.2 -3,-0.3 -2,-0.2 0.772 116.2 50.2 -88.1 -31.7 10.3 27.9 30.3 29 40 L K H < S+ 0 0 146 -4,-1.5 2,-0.9 -5,-0.3 -2,-0.2 0.862 95.8 74.9 -72.2 -41.0 12.4 29.3 27.5 30 41 L D < + 0 0 67 -4,-3.2 -1,-0.1 1,-0.2 -4,-0.0 -0.678 51.5 166.7 -81.9 107.2 9.7 29.2 24.7 31 42 L Q + 0 0 124 -2,-0.9 -1,-0.2 2,-0.0 2,-0.1 0.500 43.2 99.9 -97.6 -8.0 7.3 32.0 25.4 32 43 L L - 0 0 107 1,-0.1 -2,-0.0 2,-0.1 0, 0.0 -0.449 56.4-156.4 -77.5 156.3 5.4 32.0 22.1 33 44 L D + 0 0 32 -2,-0.1 156,-2.4 156,-0.1 2,-0.2 0.318 55.7 104.7-118.1 7.3 2.0 30.2 21.9 34 45 L N S S- 0 0 61 154,-0.1 2,-0.4 155,-0.1 156,-0.1 -0.605 76.3-111.0 -86.4 151.2 1.6 29.3 18.3 35 46 L L - 0 0 26 154,-0.4 3,-0.2 -2,-0.2 -2,-0.1 -0.674 28.5-174.2 -82.2 133.8 2.1 25.7 17.2 36 47 L L S S+ 0 0 135 -2,-0.4 2,-2.0 1,-0.2 -1,-0.2 0.877 79.5 57.8 -91.3 -50.6 5.2 25.2 15.1 37 48 L L S S- 0 0 76 2,-0.1 -1,-0.2 3,-0.1 5,-0.1 -0.559 88.6-159.3 -81.9 76.7 4.7 21.5 14.3 38 49 L K >> - 0 0 102 -2,-2.0 3,-1.2 -3,-0.2 4,-0.6 -0.037 28.5-113.1 -53.3 158.1 1.3 22.0 12.7 39 50 L E H 3> S+ 0 0 121 1,-0.3 4,-2.2 2,-0.2 -1,-0.1 0.486 111.8 79.1 -74.1 -1.3 -1.1 19.1 12.4 40 51 L S H 3> S+ 0 0 79 1,-0.2 4,-2.1 2,-0.2 -1,-0.3 0.887 91.1 53.4 -69.9 -36.2 -0.5 19.4 8.6 41 52 L L H <> S+ 0 0 46 -3,-1.2 4,-1.8 1,-0.2 -1,-0.2 0.837 106.1 53.1 -63.8 -33.9 2.7 17.6 9.4 42 53 L L H X S+ 0 0 75 -4,-0.6 4,-0.8 2,-0.2 -2,-0.2 0.936 106.5 50.3 -67.4 -47.8 0.7 14.9 11.2 43 54 L E H >X S+ 0 0 88 -4,-2.2 4,-1.1 1,-0.2 3,-0.9 0.889 108.7 54.2 -57.1 -39.3 -1.5 14.4 8.1 44 55 L D H ><>S+ 0 0 74 -4,-2.1 5,-0.6 1,-0.3 3,-0.5 0.903 102.0 56.4 -61.5 -41.5 1.6 14.1 6.1 45 56 L F H 3<5S+ 0 0 75 -4,-1.8 -1,-0.3 1,-0.3 -2,-0.2 0.711 114.0 42.0 -62.5 -18.3 2.8 11.3 8.4 46 57 L K H <<5S+ 0 0 145 -3,-0.9 -1,-0.3 -4,-0.8 -2,-0.2 0.558 100.4 88.1-103.1 -14.8 -0.4 9.6 7.5 47 58 L G T X<5S- 0 0 35 -4,-1.1 3,-2.2 -3,-0.5 2,-0.2 -0.257 101.3 -95.5 -76.4 171.6 -0.3 10.4 3.8 48 59 L Y T 3 5S+ 0 0 230 1,-0.3 -1,-0.1 2,-0.1 -3,-0.1 0.037 126.6 62.7 -80.7 32.6 1.5 8.1 1.4 49 60 L L T 3> S+ 0 0 9 -3,-2.2 4,-2.8 1,-0.2 5,-0.2 0.870 70.4 50.0 -42.1 -57.8 4.6 9.4 5.5 51 62 L b H > S+ 0 0 33 1,-0.2 4,-2.5 2,-0.2 -1,-0.2 0.934 113.0 46.8 -52.0 -51.6 8.0 7.7 5.5 52 63 L Q H > S+ 0 0 100 1,-0.2 4,-1.9 2,-0.2 -1,-0.2 0.879 112.7 50.0 -60.3 -38.7 9.7 10.6 3.6 53 64 L A H X S+ 0 0 8 -4,-2.4 4,-1.8 -9,-0.2 -1,-0.2 0.905 112.3 47.5 -66.0 -42.1 8.1 13.1 6.0 54 65 L L H X S+ 0 0 51 -4,-2.8 4,-2.3 -5,-0.2 -2,-0.2 0.878 110.8 50.6 -66.9 -40.2 9.2 11.2 9.0 55 66 L S H X S+ 0 0 8 -4,-2.5 4,-2.3 -5,-0.2 -1,-0.2 0.897 109.5 51.9 -64.4 -43.3 12.8 10.7 7.8 56 67 L E H X S+ 0 0 111 -4,-1.9 4,-3.3 -5,-0.2 -1,-0.2 0.900 109.8 48.2 -61.2 -44.5 13.1 14.4 7.0 57 68 L M H X S+ 0 0 33 -4,-1.8 4,-3.2 2,-0.2 5,-0.3 0.959 110.9 49.0 -62.7 -51.7 12.0 15.4 10.5 58 69 L I H X S+ 0 0 13 -4,-2.3 4,-2.4 1,-0.2 -1,-0.2 0.917 115.8 46.1 -54.0 -42.2 14.3 13.1 12.3 59 70 L Q H X S+ 0 0 64 -4,-2.3 4,-2.6 -5,-0.2 5,-0.5 0.926 111.1 52.8 -63.6 -46.4 17.1 14.4 10.0 60 71 L F H X>S+ 0 0 73 -4,-3.3 4,-2.5 2,-0.2 5,-1.4 0.940 113.4 42.0 -54.0 -54.9 15.9 18.0 10.7 61 72 L Y H <>S+ 0 0 88 -4,-3.2 5,-2.5 1,-0.2 -2,-0.2 0.952 118.3 44.5 -59.1 -53.7 16.1 17.6 14.4 62 73 L L H <5S+ 0 0 22 -4,-2.4 -1,-0.2 -5,-0.3 -2,-0.2 0.770 126.3 30.1 -63.3 -30.7 19.4 15.7 14.5 63 74 L E H <5S+ 0 0 114 -4,-2.6 -3,-0.2 -5,-0.2 -2,-0.2 0.873 134.4 15.6 -97.7 -47.5 21.1 18.0 12.0 64 75 L E T X5S+ 0 0 100 -4,-2.5 4,-1.6 -5,-0.5 -3,-0.2 0.930 125.8 36.8 -92.4 -68.0 19.7 21.4 12.3 65 76 L V H >> S+ 0 0 49 0, 0.0 4,-1.4 0, 0.0 -1,-0.2 0.878 110.5 47.7 -61.0 -37.8 23.1 20.8 17.0 68 79 L Q H X - 0 0 45 -4,-2.1 3,-2.1 1,-0.1 4,-0.6 -0.658 64.2-175.0-136.6 80.8 23.6 26.6 25.5 74 85 L P H 3> S+ 0 0 87 0, 0.0 4,-0.6 0, 0.0 3,-0.2 0.682 71.5 91.8 -47.0 -19.8 26.1 23.9 26.8 75 86 L D H 34 S+ 0 0 113 1,-0.3 4,-0.2 2,-0.1 3,-0.1 0.874 110.4 11.7 -43.7 -43.8 24.0 23.9 30.0 76 87 L I H <> S+ 0 0 8 -3,-2.1 4,-3.2 -7,-0.2 5,-0.4 0.297 91.6 117.9-118.1 5.0 22.0 21.1 28.4 77 88 L K H X S+ 0 0 91 -4,-0.6 4,-1.1 -7,-0.3 -2,-0.1 0.749 87.9 41.6 -44.8 -26.7 24.3 20.3 25.5 78 89 L A H X S+ 0 0 60 -4,-0.6 4,-2.8 2,-0.2 5,-0.3 0.941 111.1 50.7 -84.5 -61.3 24.6 16.9 27.1 79 90 L H H > S+ 0 0 90 1,-0.3 4,-1.0 -4,-0.2 -2,-0.2 0.791 116.3 46.8 -46.6 -32.5 21.0 16.3 28.2 80 91 L V H X S+ 0 0 6 -4,-3.2 4,-2.5 2,-0.2 -1,-0.3 0.897 107.8 51.8 -79.0 -44.8 20.1 17.2 24.6 81 92 L N H X S+ 0 0 82 -4,-1.1 4,-2.5 -5,-0.4 -2,-0.2 0.886 106.5 57.4 -59.5 -36.7 22.7 15.0 22.9 82 93 L S H X S+ 0 0 61 -4,-2.8 4,-2.3 2,-0.2 -1,-0.2 0.927 105.6 48.8 -58.5 -45.8 21.4 12.1 25.0 83 94 L L H X S+ 0 0 27 -4,-1.0 4,-2.0 -5,-0.3 -1,-0.2 0.941 107.8 56.5 -58.5 -46.0 18.0 12.7 23.6 84 95 L G H X S+ 0 0 6 -4,-2.5 4,-2.8 1,-0.2 5,-0.3 0.910 105.5 50.4 -51.2 -47.5 19.6 12.7 20.2 85 96 L E H X S+ 0 0 100 -4,-2.5 4,-3.7 1,-0.2 5,-0.3 0.959 107.3 52.2 -56.9 -53.0 21.1 9.3 20.8 86 97 L N H X S+ 0 0 41 -4,-2.3 4,-0.6 1,-0.2 -1,-0.2 0.825 111.9 50.3 -51.6 -33.4 17.7 7.9 21.9 87 98 L L H >X S+ 0 0 26 -4,-2.0 4,-2.8 2,-0.2 3,-1.7 0.988 112.0 42.0 -70.1 -60.9 16.5 9.3 18.6 88 99 L K H 3X S+ 0 0 87 -4,-2.8 4,-2.9 1,-0.3 5,-0.2 0.893 112.7 57.5 -51.5 -41.5 19.1 7.8 16.3 89 100 L T H 3X S+ 0 0 57 -4,-3.7 4,-1.0 -5,-0.3 -1,-0.3 0.772 110.0 44.6 -60.6 -27.1 18.7 4.6 18.4 90 101 L L H < S- 0 0 11 -4,-0.5 3,-1.4 1,-0.3 4,-0.4 -0.838 94.6-141.4-113.5 91.1 12.2 -3.7 10.5 98 109 L H G > S+ 0 0 136 -2,-0.7 3,-1.9 -3,-0.2 2,-0.7 0.650 82.2 61.1 -10.4-111.6 10.8 -2.7 7.0 99 110 L R G 3 S+ 0 0 235 1,-0.3 -1,-0.2 2,-0.2 -4,-0.1 0.390 103.6 54.2 0.8 -41.9 7.2 -1.3 7.1 100 111 L F G < S+ 0 0 106 -3,-1.4 -1,-0.3 -2,-0.7 -5,-0.2 0.952 127.5 7.1 -75.3 -50.4 8.2 1.6 9.4 101 112 L L X + 0 0 0 -3,-1.9 3,-1.6 -7,-0.9 -1,-0.2 -0.352 68.0 147.7-133.6 60.6 11.0 3.2 7.5 102 113 L P G > + 0 0 60 0, 0.0 3,-2.9 0, 0.0 -1,-0.1 0.881 68.5 71.6 -57.2 -39.7 11.4 1.6 4.0 103 114 L b G 3 S+ 0 0 56 1,-0.3 -2,-0.0 -3,-0.1 -8,-0.0 0.533 97.3 48.9 -57.0 -8.7 12.5 5.0 2.5 104 115 L E G < S+ 0 0 47 -3,-1.6 2,-0.4 2,-0.1 -1,-0.3 0.271 91.9 104.4-113.7 9.2 15.8 4.8 4.3 105 116 L N < - 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