==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=26-JUN-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER CHAPERONE 25-MAR-11 2YEI . COMPND 2 MOLECULE: HEAT SHOCK PROTEIN HSP 90-ALPHA; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR S.D.ROUGHLEY,R.E.HUBBARD,L.M.BAKER . 208 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 10750.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 157 75.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 4 1.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 41 19.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 18 8.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 32 15.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 56 26.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 5 2.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 1 0 0 0 0 0 1 1 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 0 2 0 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 16 A H 0 0 187 0, 0.0 2,-0.6 0, 0.0 158,-0.4 0.000 360.0 360.0 360.0 169.4 7.1 28.5 38.4 2 17 A V - 0 0 70 156,-0.1 2,-0.4 154,-0.0 156,-0.2 -0.750 360.0-158.6 -92.5 114.5 8.4 27.4 34.9 3 18 A E E -A 157 0A 71 154,-1.9 154,-1.7 -2,-0.6 2,-0.5 -0.755 9.4-143.9 -90.2 135.4 11.2 24.8 34.9 4 19 A T E -A 156 0A 100 -2,-0.4 2,-0.3 152,-0.2 152,-0.2 -0.872 18.6-175.1-104.1 125.4 13.4 24.5 31.7 5 20 A F E -A 155 0A 48 150,-3.6 150,-2.2 -2,-0.5 2,-0.4 -0.800 18.6-129.7-113.3 155.1 14.7 21.2 30.5 6 21 A A E -A 154 0A 77 -2,-0.3 148,-0.3 148,-0.3 2,-0.1 -0.809 25.6-115.5 -98.4 145.2 17.0 20.1 27.7 7 22 A F - 0 0 15 146,-4.5 2,-0.1 -2,-0.4 6,-0.1 -0.484 36.2-101.8 -71.5 143.8 16.3 17.5 25.2 8 23 A Q >> - 0 0 48 1,-0.1 4,-2.4 -2,-0.1 3,-0.9 -0.512 43.1-114.1 -51.9 135.5 18.4 14.3 25.2 9 24 A A H 3> S+ 0 0 69 1,-0.3 4,-3.3 2,-0.2 5,-0.1 0.760 116.8 58.4 -54.7 -29.5 20.7 15.2 22.3 10 25 A E H 3> S+ 0 0 85 2,-0.2 4,-2.3 3,-0.2 -1,-0.3 0.902 110.2 42.8 -65.5 -42.2 19.1 12.2 20.3 11 26 A I H <> S+ 0 0 0 -3,-0.9 4,-2.4 2,-0.2 5,-0.2 0.985 114.9 50.0 -65.5 -60.8 15.7 13.8 20.7 12 27 A A H X S+ 0 0 26 -4,-2.4 4,-1.6 1,-0.2 3,-0.3 0.945 111.7 49.0 -32.7 -69.9 17.0 17.3 19.9 13 28 A Q H X S+ 0 0 118 -4,-3.3 4,-2.2 1,-0.3 -1,-0.2 0.857 109.6 52.3 -45.7 -47.0 18.7 15.8 16.8 14 29 A L H X S+ 0 0 0 -4,-2.3 4,-1.7 1,-0.2 -1,-0.3 0.957 103.6 56.3 -51.1 -55.5 15.5 14.1 15.7 15 30 A M H X S+ 0 0 3 -4,-2.4 4,-2.8 -3,-0.3 -1,-0.2 0.836 106.4 51.0 -55.0 -37.2 13.5 17.3 15.9 16 31 A S H X S+ 0 0 65 -4,-1.6 4,-3.0 -5,-0.2 5,-0.5 0.974 105.2 56.2 -60.1 -51.4 15.9 19.0 13.6 17 32 A L H X S+ 0 0 44 -4,-2.2 4,-2.4 1,-0.2 -2,-0.2 0.904 112.9 41.0 -48.7 -57.6 15.6 16.2 11.1 18 33 A I H < S+ 0 0 3 -4,-1.7 -1,-0.2 1,-0.2 -2,-0.2 0.902 117.1 49.4 -48.4 -55.7 11.8 16.6 11.0 19 34 A I H < S+ 0 0 66 -4,-2.8 -1,-0.2 -5,-0.2 -2,-0.2 0.887 121.5 29.5 -56.4 -46.4 12.0 20.4 10.9 20 35 A N H < S+ 0 0 118 -4,-3.0 2,-0.2 -5,-0.2 -2,-0.2 0.675 94.6 98.2 -98.1 -14.5 14.5 20.9 8.2 21 36 A T S < S- 0 0 65 -4,-2.4 2,-0.3 -5,-0.5 -4,-0.0 -0.542 78.2-113.2 -78.0 137.5 14.1 17.8 5.9 22 37 A F + 0 0 182 -2,-0.2 2,-0.3 2,-0.0 -1,-0.1 -0.515 54.0 146.3 -69.5 126.7 12.0 18.2 2.7 23 38 A Y - 0 0 38 -2,-0.3 3,-0.1 105,-0.1 -2,-0.0 -0.791 26.6-174.3-173.0 114.2 8.8 16.2 3.0 24 39 A S + 0 0 87 -2,-0.3 2,-1.3 1,-0.2 3,-0.3 0.561 68.6 83.9-102.9 -15.2 5.5 17.2 1.6 25 40 A N > + 0 0 67 1,-0.2 3,-0.9 2,-0.1 -1,-0.2 -0.437 50.9 143.9 -87.4 60.0 3.3 14.4 2.9 26 41 A K G > + 0 0 36 -2,-1.3 3,-3.3 1,-0.2 -1,-0.2 0.774 43.7 85.5 -75.8 -30.0 2.8 16.2 6.2 27 42 A E G > S+ 0 0 10 1,-0.3 3,-1.5 -3,-0.3 4,-0.4 0.646 74.0 75.4 -49.9 -19.7 -0.8 15.3 6.9 28 43 A I G <> S+ 0 0 2 -3,-0.9 4,-1.1 1,-0.3 3,-0.4 0.705 71.1 86.1 -71.5 -18.6 0.3 12.0 8.5 29 44 A F H <> S+ 0 0 0 -3,-3.3 4,-0.6 1,-0.2 -1,-0.3 0.755 89.2 52.4 -44.6 -26.4 1.3 14.1 11.5 30 45 A L H <> S+ 0 0 2 -3,-1.5 4,-3.2 2,-0.2 -1,-0.2 0.810 98.6 53.9 -93.0 -38.6 -2.4 13.7 12.7 31 46 A R H > S+ 0 0 56 -3,-0.4 4,-2.4 -4,-0.4 -1,-0.2 0.688 104.9 62.1 -68.5 -18.3 -3.1 10.0 12.6 32 47 A E H X S+ 0 0 10 -4,-1.1 4,-2.8 2,-0.2 91,-0.2 0.873 110.2 37.4 -72.4 -37.9 0.1 9.8 14.8 33 48 A L H X S+ 0 0 7 -4,-0.6 4,-3.1 2,-0.2 5,-0.2 0.889 116.0 51.5 -80.3 -46.1 -1.6 11.9 17.5 34 49 A I H >X S+ 0 0 0 -4,-3.2 4,-2.1 2,-0.2 3,-0.8 0.982 115.8 43.6 -47.8 -70.9 -5.0 10.3 16.9 35 50 A S H 3X S+ 0 0 41 -4,-2.4 4,-2.9 1,-0.3 -2,-0.2 0.856 112.6 52.2 -35.4 -59.9 -3.2 6.9 17.3 36 51 A N H 3X S+ 0 0 60 -4,-2.8 4,-0.7 1,-0.2 -1,-0.3 0.884 110.5 48.8 -42.9 -51.2 -1.2 8.2 20.3 37 52 A S H < S+ 0 0 164 -4,-2.6 3,-0.6 1,-0.2 4,-0.5 0.864 110.8 46.8 -57.5 -52.0 -7.7 -1.4 30.8 47 62 A E H >X S+ 0 0 68 -4,-1.5 4,-2.4 1,-0.2 3,-1.4 0.887 108.0 55.6 -64.7 -44.2 -6.7 -0.1 34.2 48 63 A S H 3< S+ 0 0 17 -4,-1.9 -1,-0.2 1,-0.3 -2,-0.2 0.657 91.6 75.3 -59.0 -23.1 -10.3 0.8 35.2 49 64 A L T << S+ 0 0 130 -4,-0.8 -1,-0.3 -3,-0.6 -2,-0.2 0.808 112.3 24.6 -58.3 -33.6 -11.2 -2.8 34.5 50 65 A T T <4 S+ 0 0 121 -3,-1.4 -2,-0.2 -4,-0.5 -1,-0.2 0.742 137.6 33.2 -99.3 -35.5 -9.5 -3.7 37.7 51 66 A D >< + 0 0 65 -4,-2.4 3,-1.4 -5,-0.1 -1,-0.2 -0.752 59.8 176.7-126.3 90.5 -9.9 -0.4 39.4 52 67 A P G > S+ 0 0 87 0, 0.0 3,-1.6 0, 0.0 4,-0.1 0.601 74.7 78.9 -66.6 -15.2 -13.2 1.5 38.4 53 68 A S G 3 S+ 0 0 64 1,-0.3 3,-0.2 2,-0.2 4,-0.2 0.374 78.9 74.9 -68.6 2.1 -12.3 4.3 40.9 54 69 A K G < S+ 0 0 44 -3,-1.4 3,-0.4 1,-0.2 -1,-0.3 0.585 86.7 59.0 -88.0 -10.3 -9.9 5.4 38.1 55 70 A L S X S+ 0 0 33 -3,-1.6 3,-2.8 1,-0.2 -1,-0.2 0.475 73.9 93.7-101.3 -2.2 -12.8 6.7 36.1 56 71 A D T 3 S+ 0 0 126 1,-0.3 -1,-0.2 -3,-0.2 3,-0.2 0.826 80.8 61.3 -58.2 -30.8 -13.9 9.2 38.8 57 72 A S T 3 S- 0 0 35 -3,-0.4 -1,-0.3 1,-0.2 -2,-0.1 0.410 134.7 -29.3 -72.8 2.7 -11.8 11.7 36.9 58 73 A G < - 0 0 16 -3,-2.8 -1,-0.2 108,-0.1 -2,-0.1 -0.006 44.8-158.2 143.7 110.7 -14.1 11.1 33.9 59 74 A K S S+ 0 0 160 -3,-0.2 2,-0.3 2,-0.0 -3,-0.1 0.885 72.2 93.6 -67.2 -39.7 -16.2 8.2 32.7 60 75 A E - 0 0 133 -5,-0.1 2,-0.6 1,-0.1 0, 0.0 -0.411 57.7-164.2 -72.8 125.2 -16.3 9.5 29.1 61 76 A L + 0 0 35 -2,-0.3 2,-0.3 17,-0.1 -1,-0.1 -0.889 33.3 125.8-115.6 103.7 -13.6 8.1 26.7 62 77 A H - 0 0 53 -2,-0.6 17,-1.7 139,-0.2 2,-0.4 -0.968 51.1-122.6-156.9 157.7 -13.2 10.1 23.5 63 78 A I E -Bc 78 203A 0 139,-2.9 141,-1.6 -2,-0.3 2,-0.4 -0.909 23.7-169.0-107.0 140.0 -11.0 12.1 21.0 64 79 A N E -Bc 77 204A 27 13,-2.4 13,-2.9 -2,-0.4 2,-0.6 -0.995 7.9-160.2-130.8 122.7 -11.8 15.8 20.1 65 80 A L E -Bc 76 205A 0 139,-2.4 141,-2.2 -2,-0.4 11,-0.2 -0.931 14.3-170.4-105.1 120.4 -10.1 17.7 17.3 66 81 A I E -B 75 0A 46 9,-2.6 9,-2.1 -2,-0.6 2,-0.5 -0.901 7.1-162.9-120.6 111.0 -10.4 21.5 17.7 67 82 A P E -B 74 0A 8 0, 0.0 2,-0.5 0, 0.0 7,-0.2 -0.770 7.1-178.4 -96.3 132.5 -9.4 24.0 15.0 68 83 A N E >> +B 73 0A 39 5,-3.0 5,-3.4 -2,-0.5 4,-0.9 -0.935 7.9 179.4-130.1 107.5 -8.9 27.6 16.0 69 84 A K T 45S+ 0 0 120 -2,-0.5 -1,-0.1 3,-0.2 5,-0.1 0.844 82.7 57.0 -79.2 -31.7 -8.0 29.9 13.1 70 85 A Q T 45S+ 0 0 161 1,-0.2 -1,-0.2 2,-0.1 -2,-0.0 0.875 118.3 34.0 -68.6 -39.3 -7.8 33.1 15.2 71 86 A D T 45S- 0 0 103 2,-0.1 -1,-0.2 0, 0.0 -2,-0.2 0.622 107.8-126.0 -80.1 -19.7 -5.2 31.4 17.4 72 87 A R T <5 + 0 0 72 -4,-0.9 103,-1.7 1,-0.2 2,-0.4 0.911 65.3 135.9 65.4 47.5 -3.7 29.4 14.4 73 88 A T E < -BD 68 174A 5 -5,-3.4 -5,-3.0 101,-0.2 2,-0.5 -0.974 47.7-170.2-139.0 135.1 -4.1 26.2 16.4 74 89 A L E -BD 67 173A 0 99,-1.1 99,-2.9 -2,-0.4 2,-0.4 -0.981 20.8-169.8-107.9 122.2 -5.3 22.6 16.1 75 90 A T E -BD 66 172A 15 -9,-2.1 -9,-2.6 -2,-0.5 2,-0.6 -0.873 13.2-152.0-104.9 144.6 -5.6 20.9 19.6 76 91 A I E -BD 65 171A 2 95,-1.3 95,-0.8 -2,-0.4 2,-0.3 -0.941 19.5-166.9-111.3 101.2 -6.1 17.1 19.8 77 92 A V E +BD 64 170A 23 -13,-2.9 -13,-2.4 -2,-0.6 2,-0.3 -0.667 9.8 175.0 -88.6 149.0 -7.9 16.6 23.1 78 93 A D E -BD 63 169A 7 91,-2.1 91,-2.0 -2,-0.3 2,-0.4 -0.982 36.0-137.9-154.4 138.2 -8.3 13.1 24.6 79 94 A T + 0 0 20 -17,-1.7 89,-0.2 -2,-0.3 -16,-0.1 -0.044 59.0 140.1 -82.6 38.4 -9.6 11.6 27.9 80 95 A G S S- 0 0 0 -2,-0.4 -39,-0.3 89,-0.2 58,-0.1 0.079 72.8 -79.8 -82.5-179.4 -6.7 9.2 28.3 81 96 A I S S- 0 0 13 -41,-3.2 59,-0.5 1,-0.1 87,-0.2 0.900 73.1-152.9 -41.8 -44.0 -4.6 7.8 31.2 82 97 A G - 0 0 5 57,-0.1 2,-0.4 85,-0.1 87,-0.1 -0.385 10.2 -74.3 93.2 179.7 -2.5 11.1 31.0 83 98 A M - 0 0 38 85,-0.5 56,-0.7 -2,-0.1 62,-0.2 -0.937 31.0-149.8-125.3 141.0 1.0 12.0 31.8 84 99 A T > - 0 0 24 -2,-0.4 4,-2.4 54,-0.1 5,-0.1 -0.300 36.9-101.5 -96.3-176.3 2.7 12.5 35.1 85 100 A K H > S+ 0 0 67 2,-0.2 4,-3.6 1,-0.2 5,-0.3 0.972 126.4 52.1 -70.8 -52.6 5.6 14.8 35.8 86 101 A A H >>S+ 0 0 49 2,-0.2 5,-4.0 3,-0.2 4,-1.4 0.738 109.4 53.8 -50.3 -35.5 8.1 11.9 35.7 87 102 A D H 4>S+ 0 0 36 3,-0.2 5,-1.9 4,-0.2 6,-0.5 0.981 114.5 35.9 -55.1 -76.8 6.4 11.1 32.5 88 103 A L H <5S+ 0 0 12 -4,-2.4 5,-0.4 1,-0.2 -2,-0.2 0.866 128.6 36.5 -51.5 -49.4 7.0 14.6 30.9 89 104 A I H <5S- 0 0 23 -4,-3.6 -1,-0.2 -5,-0.1 -3,-0.2 0.895 137.5 -7.2 -70.3 -46.4 10.4 15.1 32.5 90 105 A N T X5S+ 0 0 100 -4,-1.4 4,-1.0 -5,-0.3 -3,-0.2 0.728 119.0 58.0-130.9 -30.7 12.1 11.6 32.6 91 106 A N H > S+ 0 0 6 -6,-0.5 4,-0.7 -5,-0.4 -1,-0.2 0.812 107.4 52.8 -33.4 -44.3 12.6 11.1 27.4 94 109 A T H >< S+ 0 0 77 -4,-1.0 3,-0.5 2,-0.2 4,-0.4 0.984 115.2 35.0 -64.5 -61.1 13.9 7.5 28.2 95 110 A I H >X S+ 0 0 111 -4,-1.6 3,-2.4 1,-0.2 4,-1.9 0.959 114.4 56.6 -56.3 -61.5 11.7 5.5 25.7 96 111 A A H 3X S+ 0 0 9 -4,-2.2 4,-2.1 1,-0.3 -1,-0.2 0.768 96.8 68.7 -32.0 -36.6 11.7 8.2 23.0 97 112 A K H S+ 0 0 77 -3,-2.4 4,-1.7 -4,-0.4 5,-0.3 0.815 112.1 58.1 -89.2 -50.4 15.6 4.3 21.6 99 114 A G H X S+ 0 0 13 -4,-1.9 4,-2.4 1,-0.2 -2,-0.2 0.891 105.2 55.6 -42.1 -42.9 12.7 5.0 19.3 100 115 A T H X S+ 0 0 1 -4,-2.1 4,-2.0 -5,-0.2 -1,-0.2 0.925 106.3 45.6 -60.1 -52.3 14.9 7.8 17.9 101 116 A K H X S+ 0 0 144 -4,-0.6 4,-3.6 -3,-0.2 5,-0.2 0.950 115.0 46.2 -58.3 -57.5 18.0 5.8 17.0 102 117 A A H X S+ 0 0 39 -4,-1.7 4,-3.0 1,-0.2 -1,-0.2 0.933 112.6 51.8 -46.7 -53.0 16.1 2.9 15.3 103 118 A F H < S+ 0 0 1 -4,-2.4 -1,-0.2 -5,-0.3 -2,-0.2 0.860 115.0 42.9 -55.3 -37.3 14.0 5.4 13.4 104 119 A M H >X S+ 0 0 39 -4,-2.0 3,-1.3 -3,-0.2 4,-0.6 0.849 110.7 52.0 -85.2 -39.2 17.2 7.1 12.3 105 120 A E H >< S+ 0 0 134 -4,-3.6 3,-0.6 1,-0.2 -2,-0.2 0.977 106.6 57.9 -49.3 -59.1 19.2 4.0 11.5 106 121 A A T 3<>S+ 0 0 27 -4,-3.0 5,-1.2 -5,-0.2 -1,-0.2 0.265 93.0 75.9 -54.5 11.3 16.1 3.0 9.4 107 122 A L T <45S+ 0 0 38 -3,-1.3 2,-0.5 1,-0.3 3,-0.4 0.913 90.3 44.4-101.1 -51.8 16.5 6.2 7.3 108 123 A Q T <<5S+ 0 0 162 -4,-0.6 -1,-0.3 -3,-0.6 4,-0.0 -0.863 102.6 63.4 -82.3 139.5 19.4 5.7 5.0 109 124 A A T 5S- 0 0 103 -2,-0.5 -1,-0.2 -3,-0.1 -3,-0.0 0.378 128.3-103.5 90.4 13.3 18.4 2.2 4.0 110 125 A G T 5S+ 0 0 69 -3,-0.4 -3,-0.2 1,-0.1 -2,-0.2 0.542 74.2 141.4 42.5 36.3 15.5 4.3 2.6 111 126 A A < - 0 0 28 -5,-1.2 2,-0.2 -8,-0.1 -2,-0.1 -0.326 42.0-144.1 -72.7-178.7 12.6 3.9 5.0 112 127 A D > - 0 0 64 -2,-0.1 3,-0.7 -4,-0.0 -1,-0.1 -0.754 19.1 -89.4-144.1-169.8 10.8 7.2 5.4 113 128 A I G > S+ 0 0 12 1,-0.3 3,-2.2 -2,-0.2 4,-0.2 0.725 107.6 73.1 -83.7 -27.1 9.0 9.6 7.8 114 129 A S G 3 S+ 0 0 29 1,-0.3 -1,-0.3 2,-0.1 3,-0.2 0.519 98.5 59.2 -62.2 0.0 5.4 8.5 7.3 115 130 A M G X + 0 0 50 -3,-0.7 3,-1.3 1,-0.1 -1,-0.3 0.333 63.5 111.1-113.7 3.9 6.8 5.6 9.4 116 131 A I G X >S+ 0 0 1 -3,-2.2 5,-1.5 1,-0.3 3,-0.7 0.673 72.5 66.6 -51.0 -19.6 7.9 7.5 12.5 117 132 A G G > 5S+ 0 0 28 1,-0.2 3,-2.2 -3,-0.2 5,-0.3 0.880 86.8 62.0 -74.0 -40.7 5.1 5.7 14.3 118 133 A Q G < 5S+ 0 0 150 -3,-1.3 -1,-0.2 1,-0.3 -2,-0.1 0.102 104.1 55.8 -71.3 23.0 6.4 2.1 14.1 119 134 A F G < 5S- 0 0 45 -3,-0.7 -1,-0.3 -17,-0.0 -16,-0.2 0.192 114.2-112.0-142.7 5.9 9.3 3.5 16.1 120 135 A G T < 5S+ 0 0 63 -3,-2.2 -3,-0.2 1,-0.1 3,-0.2 0.529 93.4 99.9 72.7 9.3 7.4 4.9 19.1 121 136 A V > < + 0 0 3 -5,-1.5 3,-0.8 -22,-0.2 4,-0.2 0.186 35.1 124.5-117.7 18.1 8.2 8.6 18.3 122 137 A G G > + 0 0 3 -5,-0.3 3,-4.5 -6,-0.2 4,-0.3 0.872 63.5 65.8 -37.2 -64.8 5.0 9.7 16.6 123 138 A F G > S+ 0 0 37 1,-0.3 3,-2.0 -91,-0.2 -1,-0.2 0.847 92.7 62.0 -30.2 -54.7 4.3 12.7 18.9 124 139 A Y G X S+ 0 0 21 -3,-0.8 3,-1.6 1,-0.3 -1,-0.3 0.639 81.7 86.3 -54.4 -7.9 7.4 14.4 17.5 125 140 A S G X S+ 0 0 1 -3,-4.5 3,-2.8 1,-0.3 4,-0.3 0.867 70.1 77.5 -58.5 -38.4 5.5 14.2 14.1 126 141 A A G X> S+ 0 0 0 -3,-2.0 4,-3.5 -4,-0.3 3,-2.3 0.722 74.5 77.0 -38.6 -31.3 3.8 17.5 15.1 127 142 A Y G <4 S+ 0 0 1 -3,-1.6 -1,-0.3 1,-0.3 -2,-0.2 0.709 80.3 68.6 -70.5 -10.4 7.0 19.3 14.2 128 143 A L G <4 S+ 0 0 3 -3,-2.8 -1,-0.3 -4,-0.2 -2,-0.2 0.773 122.4 12.9 -65.7 -29.9 6.1 19.0 10.5 129 144 A V T <4 S+ 0 0 0 -3,-2.3 47,-2.6 -4,-0.3 2,-0.4 0.717 113.9 78.7-119.9 -30.0 3.3 21.4 11.0 130 145 A A E < -E 175 0A 1 -4,-3.5 45,-0.2 45,-0.2 3,-0.2 -0.720 46.1-168.7-103.5 126.4 3.8 23.0 14.5 131 146 A E E S+ 0 0 98 43,-2.2 2,-0.3 -2,-0.4 44,-0.2 0.784 89.3 9.5 -79.7 -26.4 6.2 25.8 15.2 132 147 A K E S-E 174 0A 63 42,-0.9 42,-2.4 -6,-0.1 2,-0.4 -0.973 72.6-152.8-148.4 138.3 5.6 25.3 19.0 133 148 A V E -EF 173 149A 0 16,-2.3 16,-2.1 -2,-0.3 2,-0.5 -0.969 4.9-166.2-117.4 137.7 3.7 22.5 20.8 134 149 A T E -EF 172 148A 15 38,-1.7 38,-3.0 -2,-0.4 2,-0.6 -0.974 4.0-162.1-121.6 113.8 1.9 22.7 24.1 135 150 A V E -EF 171 147A 5 12,-1.7 12,-2.6 -2,-0.5 2,-0.5 -0.857 5.1-173.6 -96.7 118.1 0.8 19.6 25.9 136 151 A I E +EF 170 146A 21 34,-3.0 34,-4.4 -2,-0.6 2,-0.3 -0.980 22.2 166.8-108.1 125.8 -1.8 20.1 28.7 137 152 A T E -EF 169 145A 0 8,-2.0 8,-1.7 -2,-0.5 2,-0.3 -0.926 25.3-159.6-141.7 150.8 -2.2 16.7 30.4 138 153 A K E -EF 168 144A 45 30,-3.5 30,-1.2 -2,-0.3 6,-0.2 -0.804 6.8-168.1-144.4 105.6 -3.8 15.4 33.6 139 154 A H - 0 0 26 -56,-0.7 -57,-0.1 4,-0.7 -58,-0.1 -0.384 29.4-122.4 -85.2 164.2 -2.9 12.1 35.3 140 155 A N S S+ 0 0 47 -59,-0.5 -1,-0.1 1,-0.2 -58,-0.1 0.875 108.6 39.2 -69.0 -36.4 -5.0 10.5 38.1 141 156 A D S S+ 0 0 135 2,-0.1 -1,-0.2 0, 0.0 2,-0.2 0.635 115.9 45.9 -91.7 -17.5 -2.1 10.4 40.6 142 157 A D S S- 0 0 41 1,-0.2 2,-0.1 -59,-0.1 3,-0.0 -0.494 87.4 -81.7-119.6 179.1 -0.4 13.7 39.9 143 158 A E - 0 0 116 -2,-0.2 -4,-0.7 1,-0.1 2,-0.4 -0.211 53.4 -91.2 -69.1 169.0 -1.0 17.4 39.4 144 159 A Q E -F 138 0A 25 16,-0.2 16,-1.1 -6,-0.2 2,-0.3 -0.760 50.9-166.8 -86.3 137.5 -2.1 19.0 36.0 145 160 A Y E -FG 137 159A 24 -8,-1.7 -8,-2.0 -2,-0.4 2,-0.5 -0.937 22.3-148.8-128.6 148.8 0.9 20.1 33.9 146 161 A A E -FG 136 158A 9 12,-3.3 12,-2.8 -2,-0.3 2,-0.3 -0.974 17.0-173.9-112.4 128.9 1.7 22.1 30.9 147 162 A W E +FG 135 157A 12 -12,-2.6 -12,-1.7 -2,-0.5 2,-0.3 -0.883 9.5 175.8-114.6 151.5 4.7 21.0 28.8 148 163 A E E +FG 134 156A 32 8,-2.4 8,-3.3 -2,-0.3 2,-0.3 -0.962 10.5 173.9-159.3 141.7 5.8 23.2 25.9 149 164 A S E -F 133 0A 3 -16,-2.1 -16,-2.3 -2,-0.3 6,-0.1 -0.926 24.2-172.9-153.3 129.0 8.6 23.2 23.4 150 165 A S - 0 0 71 1,-0.4 5,-0.1 4,-0.4 -16,-0.1 0.216 57.0-126.4 -96.9 12.2 9.3 25.3 20.4 151 166 A A S > S+ 0 0 12 3,-0.4 3,-0.5 -18,-0.1 -1,-0.4 -0.269 70.5 124.2 71.4-162.9 12.1 22.8 19.9 152 167 A G T 3 S- 0 0 79 1,-0.2 -1,-0.1 -140,-0.2 -140,-0.1 0.925 103.3 -52.1 68.5 43.7 15.7 23.8 19.4 153 168 A G T 3 S+ 0 0 27 -145,-0.1 -146,-4.5 -141,-0.1 2,-0.4 0.019 115.8 76.3 98.8 -22.2 17.1 21.7 22.3 154 169 A S E < -A 6 0A 51 -3,-0.5 -4,-0.4 -148,-0.3 -3,-0.4 -0.962 47.3-168.3-135.4 140.5 14.9 22.6 25.3 155 170 A F E -A 5 0A 8 -150,-2.2 -150,-3.6 -2,-0.4 2,-0.3 -0.911 12.8-146.2-118.4 149.7 11.4 22.0 26.7 156 171 A T E -AG 4 148A 26 -8,-3.3 -8,-2.4 -2,-0.3 2,-0.3 -0.855 10.7-171.8-108.2 156.0 9.5 23.7 29.6 157 172 A V E +AG 3 147A 2 -154,-1.7 -154,-1.9 -2,-0.3 2,-0.3 -0.986 11.1 164.7-136.5 135.3 7.1 22.2 32.0 158 173 A R E - G 0 146A 89 -12,-2.8 -12,-3.3 -2,-0.3 2,-0.4 -0.971 46.4 -93.9-139.0 159.5 4.9 24.1 34.6 159 174 A T E - G 0 145A 76 -158,-0.4 -14,-0.3 -2,-0.3 2,-0.1 -0.624 52.2-129.7 -62.9 122.9 1.9 23.3 36.8 160 175 A D - 0 0 40 -16,-1.1 -16,-0.2 -2,-0.4 -1,-0.1 -0.347 26.5-173.5 -74.7 158.6 -1.1 24.5 34.7 161 176 A T + 0 0 140 -2,-0.1 -1,-0.1 3,-0.0 -2,-0.0 -0.042 50.7 110.4-136.3 28.2 -3.9 26.8 36.0 162 177 A G S S- 0 0 43 1,-0.3 3,-0.0 0, 0.0 -2,-0.0 0.185 87.1 -35.1 -81.5-152.7 -6.2 26.7 32.9 163 178 A E S S- 0 0 160 1,-0.1 2,-0.5 2,-0.1 -1,-0.3 -0.464 73.2-110.2 -61.1 140.1 -9.6 25.0 32.8 164 179 A P - 0 0 107 0, 0.0 -1,-0.1 0, 0.0 -26,-0.0 -0.726 32.2-163.6 -74.4 123.9 -9.3 21.9 35.0 165 180 A M - 0 0 34 -2,-0.5 2,-1.9 1,-0.1 -27,-0.1 0.489 17.3-141.9 -96.2 -5.2 -9.5 19.2 32.4 166 181 A G S S- 0 0 37 2,-0.1 2,-0.2 -27,-0.0 -1,-0.1 -0.329 70.1 -13.3 86.8 -61.7 -10.3 16.4 34.8 167 182 A R S S+ 0 0 4 -2,-1.9 2,-0.3 -89,-0.1 -28,-0.2 -0.706 99.4 60.3-167.3 134.2 -8.2 13.7 33.2 168 183 A G E - E 0 138A 0 -30,-1.2 -30,-3.5 -2,-0.2 -85,-0.5 -0.995 68.9 -79.2 159.4-159.9 -6.5 13.6 29.8 169 184 A T E -DE 78 137A 12 -91,-2.0 -91,-2.1 -2,-0.3 2,-0.4 -0.946 27.2-170.5-140.3 128.9 -4.0 15.1 27.3 170 185 A K E -DE 77 136A 61 -34,-4.4 -34,-3.0 -2,-0.3 2,-0.5 -0.975 7.9-164.4-107.1 136.2 -4.7 18.2 25.2 171 186 A V E -DE 76 135A 13 -95,-0.8 -95,-1.3 -2,-0.4 2,-0.9 -0.931 3.6-161.0-123.1 107.9 -2.0 18.8 22.5 172 187 A I E -DE 75 134A 30 -38,-3.0 -38,-1.7 -2,-0.5 2,-0.6 -0.765 3.9-156.0 -96.5 104.5 -2.1 22.4 21.1 173 188 A L E -DE 74 133A 0 -99,-2.9 2,-1.1 -2,-0.9 -99,-1.1 -0.714 3.6-156.7 -73.4 119.5 -0.3 22.7 17.7 174 189 A H E -DE 73 132A 42 -42,-2.4 -43,-2.2 -2,-0.6 -42,-0.9 -0.788 30.8-141.9 -96.6 90.5 0.7 26.3 17.1 175 190 A L E - E 0 130A 0 -103,-1.7 -45,-0.2 -2,-1.1 5,-0.1 -0.161 7.4-109.9 -68.2 146.9 0.9 25.9 13.3 176 191 A K > - 0 0 46 -47,-2.6 3,-1.9 1,-0.1 -1,-0.1 -0.322 38.9-100.1 -64.1 153.1 3.5 27.5 11.1 177 192 A E T 3 S+ 0 0 151 1,-0.3 3,-0.4 2,-0.1 -1,-0.1 0.718 119.4 45.5 -47.2 -33.3 2.4 30.3 8.7 178 193 A D T 3 S+ 0 0 115 1,-0.2 -1,-0.3 -49,-0.1 3,-0.1 0.347 99.9 67.4-102.5 8.4 2.1 28.0 5.7 179 194 A Q X + 0 0 12 -3,-1.9 3,-1.6 -50,-0.2 -1,-0.2 0.118 54.6 120.4-111.8 19.3 0.3 25.0 7.1 180 195 A T G > + 0 0 56 -3,-0.4 3,-1.8 1,-0.3 -1,-0.1 0.444 50.3 92.3 -70.0 5.1 -3.2 26.5 7.9 181 196 A E G > S+ 0 0 77 1,-0.3 3,-1.2 2,-0.2 -1,-0.3 0.803 78.6 60.3 -73.7 -25.0 -4.8 23.9 5.6 182 197 A Y G < S+ 0 0 4 -3,-1.6 -1,-0.3 1,-0.2 -2,-0.2 0.289 90.3 70.0 -81.9 9.0 -5.2 21.7 8.6 183 198 A L G < S+ 0 0 4 -3,-1.8 2,-0.5 -116,-0.1 -1,-0.2 0.323 82.9 96.1 -97.5 7.2 -7.4 24.4 10.2 184 199 A E X> - 0 0 66 -3,-1.2 4,-2.1 1,-0.1 3,-1.0 -0.856 69.5-146.3-106.8 123.1 -10.0 23.6 7.5 185 200 A E H 3> S+ 0 0 72 -2,-0.5 4,-2.0 1,-0.3 5,-0.2 0.898 101.7 52.6 -50.8 -48.1 -12.9 21.3 8.3 186 201 A R H 3> S+ 0 0 195 1,-0.2 4,-0.7 2,-0.2 -1,-0.3 0.812 113.1 45.9 -58.9 -31.6 -13.0 19.9 4.8 187 202 A R H <> S+ 0 0 40 -3,-1.0 4,-1.1 -6,-0.3 -1,-0.2 0.777 111.6 50.2 -85.3 -29.7 -9.3 19.1 5.1 188 203 A I H X S+ 0 0 2 -4,-2.1 4,-1.6 2,-0.2 -2,-0.2 0.761 107.1 54.2 -76.4 -29.3 -9.4 17.5 8.6 189 204 A K H X S+ 0 0 118 -4,-2.0 4,-2.3 -5,-0.2 -1,-0.2 0.787 106.5 53.6 -73.7 -33.3 -12.3 15.2 7.6 190 205 A E H X S+ 0 0 94 -4,-0.7 4,-1.9 -5,-0.2 -2,-0.2 0.866 108.8 46.3 -74.2 -40.2 -10.3 13.9 4.7 191 206 A I H X S+ 0 0 1 -4,-1.1 4,-3.5 2,-0.2 5,-0.5 0.908 113.9 48.9 -65.8 -43.7 -7.2 12.9 6.7 192 207 A V H X S+ 0 0 24 -4,-1.6 4,-2.7 2,-0.2 -2,-0.2 0.981 113.3 46.2 -60.8 -57.9 -9.4 11.2 9.4 193 208 A K H < S+ 0 0 164 -4,-2.3 4,-0.3 1,-0.2 -1,-0.2 0.876 119.8 42.6 -48.1 -43.8 -11.3 9.2 6.8 194 209 A K H < S+ 0 0 98 -4,-1.9 3,-0.2 -5,-0.2 -2,-0.2 0.977 131.2 16.2 -66.3 -57.4 -8.0 8.3 5.1 195 210 A H H < S+ 0 0 51 -4,-3.5 -3,-0.2 1,-0.2 -2,-0.2 0.545 131.3 31.4-105.2 -15.8 -5.7 7.5 8.0 196 211 A S >< + 0 0 9 -4,-2.7 3,-0.8 -5,-0.5 -1,-0.2 -0.099 65.3 126.6-139.4 36.3 -7.8 7.0 11.1 197 212 A Q T 3 S+ 0 0 102 -4,-0.3 -4,-0.1 -3,-0.2 -1,-0.1 0.667 76.7 52.3 -75.4 -6.8 -11.2 5.5 10.2 198 213 A F T 3 + 0 0 187 -3,-0.1 2,-0.3 2,-0.0 -1,-0.2 0.403 66.8 132.5-112.7 7.0 -10.8 2.6 12.6 199 214 A I < - 0 0 39 -3,-0.8 2,-2.0 1,-0.2 4,-0.1 -0.381 56.7-137.0 -60.0 117.8 -10.0 4.2 15.9 200 215 A G S S+ 0 0 59 -2,-0.3 -1,-0.2 2,-0.1 -2,-0.0 -0.176 77.5 79.7 -79.2 46.4 -12.3 2.5 18.4 201 216 A Y S S- 0 0 22 -2,-2.0 2,-0.3 -139,-0.0 -139,-0.2 -0.981 93.8 -91.6-148.6 144.5 -13.1 5.9 20.1 202 217 A P - 0 0 80 0, 0.0 -139,-2.9 0, 0.0 2,-0.6 -0.439 38.5-161.2 -58.4 117.4 -15.5 8.7 19.2 203 218 A I E -c 63 0A 44 -2,-0.3 2,-0.6 -141,-0.2 -139,-0.2 -0.945 7.1-169.6-101.8 120.7 -13.6 11.3 17.1 204 219 A T E -c 64 0A 67 -141,-1.6 -139,-2.4 -2,-0.6 2,-1.0 -0.931 10.1-158.4-117.3 109.5 -15.4 14.6 17.0 205 220 A L E -c 65 0A 33 -2,-0.6 -139,-0.2 -141,-0.2 2,-0.1 -0.780 19.0-143.9 -87.9 105.5 -14.2 17.2 14.6 206 221 A F - 0 0 84 -141,-2.2 2,-0.2 -2,-1.0 -142,-0.0 -0.426 8.9-143.4 -61.1 136.6 -15.3 20.5 16.0 207 222 A V 0 0 97 -2,-0.1 -1,-0.1 -141,-0.1 -23,-0.0 -0.447 360.0 360.0 -88.5 176.0 -16.4 23.2 13.5 208 223 A E 0 0 120 -2,-0.2 -140,-0.1 -142,-0.0 -23,-0.0 -0.871 360.0 360.0-122.7 360.0 -15.8 26.9 13.9