==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=30-OCT-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER CHAPERONE 26-MAY-11 2YKE . COMPND 2 MOLECULE: HEAT SHOCK PROTEIN HSP 90-ALPHA; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR A.DUPUY,F.VALLEE . 207 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 10903.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 156 75.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 4 1.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 40 19.3 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 15 7.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 28 13.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 62 30.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 5 2.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 1 0 0 0 0 0 1 1 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 0 2 1 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 17 A M 0 0 123 0, 0.0 2,-0.3 0, 0.0 156,-0.2 0.000 360.0 360.0 360.0 120.4 8.1 27.4 34.9 2 18 A E E -A 156 0A 103 154,-2.5 154,-2.1 2,-0.0 2,-0.4 -0.794 360.0-147.2 -99.6 142.2 11.1 25.0 34.7 3 19 A T E -A 155 0A 99 -2,-0.3 2,-0.3 152,-0.2 152,-0.2 -0.926 15.6-172.7-115.3 134.0 13.3 24.8 31.6 4 20 A F E -A 154 0A 51 150,-3.1 150,-2.2 -2,-0.4 2,-0.5 -0.935 20.8-123.3-127.0 151.9 15.0 21.6 30.5 5 21 A A E -A 153 0A 84 -2,-0.3 148,-0.3 148,-0.2 2,-0.1 -0.783 24.0-127.6 -94.5 131.5 17.5 20.6 27.8 6 22 A F - 0 0 24 146,-2.2 86,-0.0 -2,-0.5 2,-0.0 -0.478 30.1-112.3 -68.1 144.2 16.7 18.0 25.3 7 23 A Q > - 0 0 96 -2,-0.1 4,-2.4 1,-0.1 5,-0.2 -0.275 35.7 -99.5 -68.7 163.0 19.4 15.3 25.0 8 24 A A H > S+ 0 0 76 2,-0.2 4,-2.3 1,-0.2 5,-0.1 0.849 115.5 52.4 -59.5 -40.6 21.3 15.2 21.7 9 25 A E H > S+ 0 0 48 2,-0.2 4,-2.3 1,-0.2 -1,-0.2 0.970 113.9 40.8 -65.0 -52.5 19.4 12.4 19.9 10 26 A I H > S+ 0 0 8 1,-0.2 4,-2.7 2,-0.2 -1,-0.2 0.888 113.5 54.8 -64.5 -38.0 15.9 13.8 20.3 11 27 A A H X S+ 0 0 28 -4,-2.4 4,-2.3 1,-0.2 -1,-0.2 0.932 109.3 48.3 -59.9 -40.1 17.2 17.3 19.6 12 28 A Q H X S+ 0 0 121 -4,-2.3 4,-2.5 1,-0.2 -2,-0.2 0.897 110.6 51.0 -65.7 -40.1 18.7 16.0 16.3 13 29 A L H X S+ 0 0 0 -4,-2.3 4,-2.8 2,-0.2 5,-0.2 0.923 108.1 52.1 -64.2 -41.3 15.4 14.3 15.4 14 30 A M H X S+ 0 0 2 -4,-2.7 4,-2.4 1,-0.2 -2,-0.2 0.937 111.2 47.6 -60.1 -44.4 13.5 17.5 16.1 15 31 A S H X S+ 0 0 61 -4,-2.3 4,-3.0 1,-0.2 5,-0.3 0.895 110.3 52.5 -62.3 -40.6 15.9 19.3 13.7 16 32 A L H X S+ 0 0 40 -4,-2.5 4,-2.5 2,-0.2 -2,-0.2 0.924 112.0 45.2 -59.1 -47.1 15.5 16.6 11.1 17 33 A I H < S+ 0 0 2 -4,-2.8 -2,-0.2 1,-0.2 -1,-0.2 0.892 117.9 43.3 -65.4 -40.4 11.7 16.9 11.2 18 34 A I H < S+ 0 0 62 -4,-2.4 -2,-0.2 -5,-0.2 -1,-0.2 0.883 123.9 34.3 -71.9 -38.4 11.7 20.7 11.1 19 35 A N H < S+ 0 0 126 -4,-3.0 -2,-0.2 -5,-0.2 -3,-0.2 0.704 91.0 97.6 -93.2 -27.2 14.5 20.9 8.3 20 36 A T S < S- 0 0 62 -4,-2.5 2,-0.6 -5,-0.3 -4,-0.0 -0.440 75.9-120.4 -70.1 138.4 13.9 17.9 6.0 21 37 A F + 0 0 185 -2,-0.1 2,-0.3 2,-0.0 -1,-0.1 -0.694 52.8 147.5 -77.5 118.8 12.0 18.5 2.8 22 38 A Y - 0 0 42 -2,-0.6 3,-0.1 -5,-0.1 -2,-0.0 -0.814 30.0-168.5-158.1 107.3 9.0 16.1 3.1 23 39 A S S S+ 0 0 94 -2,-0.3 2,-2.3 1,-0.2 3,-0.3 0.754 71.2 84.1 -75.6 -26.1 5.6 17.0 1.5 24 40 A N > + 0 0 64 1,-0.2 3,-1.0 2,-0.1 -1,-0.2 -0.307 49.3 143.6 -76.5 54.7 3.5 14.2 3.2 25 41 A K T > + 0 0 36 -2,-2.3 3,-2.1 1,-0.2 -1,-0.2 0.738 46.6 84.8 -69.4 -23.1 3.0 16.3 6.4 26 42 A E T >> + 0 0 17 -3,-0.3 3,-1.6 1,-0.3 4,-0.6 0.652 68.7 80.9 -58.0 -20.3 -0.7 15.1 7.0 27 43 A I H <> S+ 0 0 1 -3,-1.0 4,-1.9 1,-0.3 -1,-0.3 0.687 71.4 80.6 -61.7 -16.3 0.5 12.0 8.8 28 44 A F H <> S+ 0 0 0 -3,-2.1 4,-2.2 1,-0.2 -1,-0.3 0.865 89.3 54.2 -55.7 -35.9 1.0 14.0 12.0 29 45 A L H <> S+ 0 0 0 -3,-1.6 4,-2.7 1,-0.2 5,-0.2 0.931 106.1 49.5 -68.2 -43.3 -2.7 13.7 12.6 30 46 A R H X S+ 0 0 67 -4,-0.6 4,-2.5 1,-0.2 -1,-0.2 0.892 111.2 52.1 -56.6 -40.4 -2.8 9.9 12.4 31 47 A E H X S+ 0 0 14 -4,-1.9 4,-2.1 2,-0.2 -2,-0.2 0.918 112.0 43.4 -67.0 -42.0 0.2 9.8 14.8 32 48 A L H X S+ 0 0 3 -4,-2.2 4,-2.4 2,-0.2 -2,-0.2 0.891 114.2 50.2 -71.5 -39.1 -1.5 12.0 17.4 33 49 A I H X S+ 0 0 0 -4,-2.7 4,-2.9 2,-0.2 -2,-0.2 0.910 110.4 51.5 -63.8 -41.4 -4.8 10.2 17.1 34 50 A S H X S+ 0 0 44 -4,-2.5 4,-2.7 -5,-0.2 -2,-0.2 0.916 109.0 50.2 -62.4 -42.3 -3.0 6.9 17.5 35 51 A N H X S+ 0 0 58 -4,-2.1 4,-2.2 2,-0.2 -2,-0.2 0.925 112.0 48.0 -60.4 -42.0 -1.3 8.2 20.7 36 52 A S H X S+ 0 0 4 -4,-2.4 4,-2.3 2,-0.2 -2,-0.2 0.930 111.0 50.6 -63.8 -44.7 -4.7 9.3 22.1 37 53 A S H X S+ 0 0 13 -4,-2.9 4,-2.9 1,-0.2 -2,-0.2 0.913 110.8 49.2 -59.1 -43.6 -6.2 5.9 21.2 38 54 A D H X S+ 0 0 92 -4,-2.7 4,-1.9 1,-0.2 -1,-0.2 0.899 110.9 49.5 -64.5 -38.0 -3.3 4.2 23.0 39 55 A A H X S+ 0 0 20 -4,-2.2 4,-2.0 2,-0.2 41,-1.3 0.866 111.7 49.5 -68.3 -34.2 -3.7 6.4 26.1 40 56 A L H X S+ 0 0 0 -4,-2.3 4,-2.6 39,-0.3 5,-0.2 0.922 109.1 51.5 -71.0 -41.1 -7.5 5.7 26.1 41 57 A D H X S+ 0 0 60 -4,-2.9 4,-2.7 1,-0.2 -2,-0.2 0.883 109.1 53.3 -61.4 -35.6 -6.9 1.9 25.8 42 58 A K H X S+ 0 0 121 -4,-1.9 4,-2.4 2,-0.2 -2,-0.2 0.928 111.8 41.2 -67.6 -48.3 -4.5 2.2 28.8 43 59 A I H X S+ 0 0 0 -4,-2.0 4,-2.4 2,-0.2 -1,-0.2 0.919 115.3 52.6 -67.9 -36.9 -6.9 3.9 31.2 44 60 A R H X S+ 0 0 107 -4,-2.6 4,-0.7 2,-0.2 -2,-0.2 0.947 111.0 46.5 -62.3 -46.1 -9.8 1.6 30.0 45 61 A Y H >X S+ 0 0 171 -4,-2.7 3,-1.4 1,-0.2 4,-0.6 0.938 111.9 49.7 -62.8 -44.0 -7.7 -1.4 30.7 46 62 A E H >X S+ 0 0 51 -4,-2.4 4,-2.4 1,-0.3 3,-1.2 0.882 104.8 60.7 -60.7 -36.3 -6.6 -0.2 34.2 47 63 A S H 3< S+ 0 0 13 -4,-2.4 -1,-0.3 1,-0.3 -2,-0.2 0.676 91.2 67.5 -65.1 -18.7 -10.3 0.6 35.0 48 64 A L H << S+ 0 0 117 -3,-1.4 -1,-0.3 -4,-0.7 -2,-0.2 0.832 112.5 32.0 -72.5 -26.5 -11.2 -3.2 34.5 49 65 A T H << S+ 0 0 116 -3,-1.2 -2,-0.2 -4,-0.6 -1,-0.2 0.843 136.8 24.7 -91.7 -43.5 -9.1 -3.9 37.7 50 66 A D >< - 0 0 66 -4,-2.4 3,-2.3 1,-0.1 -1,-0.2 -0.811 63.4-175.1-124.7 92.4 -9.8 -0.6 39.5 51 67 A P G > S+ 0 0 92 0, 0.0 3,-2.0 0, 0.0 -1,-0.1 0.752 80.2 73.9 -56.9 -24.3 -13.1 1.1 38.3 52 68 A S G > S+ 0 0 59 1,-0.3 3,-2.0 2,-0.2 4,-0.3 0.651 75.5 80.9 -65.0 -11.9 -12.4 4.1 40.6 53 69 A K G < S+ 0 0 52 -3,-2.3 3,-0.4 1,-0.3 -1,-0.3 0.712 89.9 53.4 -67.1 -15.5 -9.7 5.0 37.9 54 70 A L G X S+ 0 0 29 -3,-2.0 3,-2.2 1,-0.2 -1,-0.3 0.320 75.2 99.8 -98.6 9.7 -12.7 6.5 35.9 55 71 A D T < S+ 0 0 132 -3,-2.0 -1,-0.2 1,-0.3 3,-0.2 0.833 79.9 59.4 -62.3 -24.9 -13.9 8.7 38.9 56 72 A S T 3 S- 0 0 38 -3,-0.4 -1,-0.3 -4,-0.3 -2,-0.1 0.348 134.0 -31.0 -83.9 4.3 -12.0 11.5 37.0 57 73 A G < - 0 0 29 -3,-2.2 -1,-0.3 108,-0.1 -2,-0.1 -0.106 44.2-153.1 144.0 121.5 -14.3 10.9 34.0 58 74 A K + 0 0 149 -3,-0.2 2,-0.2 -2,-0.1 -3,-0.1 0.730 68.8 99.3 -81.1 -26.5 -16.1 7.9 32.4 59 75 A E - 0 0 132 -5,-0.1 2,-0.6 1,-0.1 0, 0.0 -0.462 54.7-162.8 -71.9 130.0 -16.1 9.3 28.8 60 76 A L + 0 0 35 -2,-0.2 2,-0.3 17,-0.1 19,-0.1 -0.935 36.1 130.2-114.5 102.2 -13.5 7.9 26.5 61 77 A H - 0 0 48 -2,-0.6 17,-1.4 139,-0.2 2,-0.4 -0.951 49.0-133.2-150.8 170.9 -13.1 10.1 23.5 62 78 A I E -Bc 77 202A 0 139,-2.6 141,-2.5 -2,-0.3 2,-0.4 -0.998 20.6-168.6-130.7 125.8 -11.0 12.2 21.1 63 79 A N E -Bc 76 203A 25 13,-2.8 13,-3.0 -2,-0.4 2,-0.5 -0.958 9.7-155.1-117.0 140.8 -11.9 15.7 20.0 64 80 A L E -Bc 75 204A 0 139,-2.9 141,-2.8 -2,-0.4 11,-0.2 -0.963 16.8-173.2-114.7 118.6 -10.2 17.7 17.2 65 81 A I E -B 74 0A 53 9,-3.0 9,-2.5 -2,-0.5 2,-0.3 -0.902 5.7-169.0-123.7 104.1 -10.5 21.4 17.7 66 82 A P E -B 73 0A 7 0, 0.0 2,-0.4 0, 0.0 7,-0.2 -0.684 1.9-172.2 -88.8 147.5 -9.4 23.9 15.1 67 83 A N E >> -B 72 0A 46 5,-2.5 5,-1.9 -2,-0.3 4,-1.0 -0.871 7.9-174.7-140.7 101.8 -9.1 27.6 15.9 68 84 A K T 45S+ 0 0 130 -2,-0.4 3,-0.2 3,-0.2 -1,-0.1 0.863 84.9 55.7 -63.5 -38.9 -8.4 29.9 13.0 69 85 A Q T 45S+ 0 0 180 1,-0.2 -1,-0.2 2,-0.1 -2,-0.0 0.922 119.3 32.1 -59.9 -47.1 -8.1 33.1 15.1 70 86 A D T 45S- 0 0 109 2,-0.1 -1,-0.2 103,-0.0 -2,-0.2 0.494 104.5-129.5 -85.6 -11.4 -5.3 31.5 17.3 71 87 A R T <5 + 0 0 85 -4,-1.0 103,-2.0 1,-0.2 2,-0.4 0.917 62.3 135.6 56.0 47.2 -3.9 29.4 14.4 72 88 A T E < -BD 67 173A 13 -5,-1.9 -5,-2.5 101,-0.2 2,-0.5 -0.959 46.1-161.3-126.0 145.6 -4.1 26.2 16.6 73 89 A L E -BD 66 172A 1 99,-1.9 99,-2.8 -2,-0.4 2,-0.5 -0.997 19.6-163.1-120.6 121.5 -5.2 22.7 16.1 74 90 A T E -BD 65 171A 20 -9,-2.5 -9,-3.0 -2,-0.5 2,-0.6 -0.923 11.4-160.2-111.3 130.4 -5.9 20.9 19.4 75 91 A I E -BD 64 170A 1 95,-2.4 95,-2.7 -2,-0.5 2,-0.4 -0.949 19.1-171.4-106.3 114.9 -6.1 17.1 19.8 76 92 A V E +BD 63 169A 17 -13,-3.0 -13,-2.8 -2,-0.6 2,-0.3 -0.924 9.0 170.6-110.9 134.0 -8.0 16.4 23.1 77 93 A D E -BD 62 168A 5 91,-2.8 91,-1.6 -2,-0.4 -15,-0.2 -0.957 35.9-141.2-136.5 160.5 -8.4 12.9 24.7 78 94 A T + 0 0 22 -17,-1.4 89,-0.2 -2,-0.3 -16,-0.1 -0.194 61.3 130.9-107.1 36.3 -9.6 11.6 28.0 79 95 A G S S- 0 0 0 89,-0.1 -39,-0.3 -18,-0.1 -40,-0.1 0.168 78.8 -66.4 -72.6-163.2 -6.9 8.9 28.1 80 96 A I - 0 0 15 -41,-1.3 59,-0.5 1,-0.1 87,-0.2 0.719 68.8-151.1 -63.4 -27.2 -4.5 8.1 31.0 81 97 A G - 0 0 7 57,-0.2 2,-0.4 85,-0.1 57,-0.2 -0.130 16.8 -84.5 78.0-179.1 -2.6 11.4 30.9 82 98 A M - 0 0 38 85,-0.4 56,-0.4 62,-0.1 62,-0.2 -0.989 28.3-140.6-131.8 137.3 1.0 12.0 31.9 83 99 A T > - 0 0 23 -2,-0.4 4,-2.4 54,-0.1 5,-0.2 -0.380 36.7-101.6 -84.5 172.3 2.5 12.6 35.3 84 100 A K H > S+ 0 0 72 1,-0.2 4,-2.4 2,-0.2 5,-0.3 0.920 126.3 53.0 -60.3 -41.4 5.3 15.2 35.9 85 101 A A H >>S+ 0 0 44 1,-0.2 5,-2.2 2,-0.2 4,-2.1 0.870 108.0 50.6 -63.5 -35.3 7.8 12.2 36.0 86 102 A D H 4>S+ 0 0 41 3,-0.2 5,-2.6 4,-0.2 6,-0.3 0.947 112.1 47.9 -62.4 -47.8 6.4 10.9 32.7 87 103 A L H <5S+ 0 0 11 -4,-2.4 -2,-0.2 1,-0.2 -1,-0.2 0.856 126.1 24.6 -62.6 -40.9 6.9 14.4 31.1 88 104 A I H <5S+ 0 0 34 -4,-2.4 -3,-0.2 -5,-0.2 -2,-0.2 0.876 136.9 12.6 -92.4 -44.0 10.4 15.0 32.3 89 105 A N T X5S+ 0 0 95 -4,-2.1 4,-1.8 -5,-0.3 3,-0.4 0.894 121.0 44.1-103.0 -63.9 12.0 11.6 32.9 90 106 A N H > S+ 0 0 25 -3,-0.4 4,-2.0 -6,-0.3 -1,-0.2 0.892 104.6 49.6 -69.2 -37.6 12.9 11.3 27.8 93 109 A T H X S+ 0 0 96 -4,-1.8 4,-2.2 2,-0.2 5,-0.2 0.927 113.9 45.2 -64.4 -44.0 14.1 7.7 28.0 94 110 A I H X S+ 0 0 83 -4,-1.7 4,-2.9 1,-0.2 5,-0.4 0.899 109.8 55.1 -66.5 -41.4 11.5 6.7 25.3 95 111 A A H X S+ 0 0 7 -4,-2.7 4,-2.0 2,-0.2 -1,-0.2 0.899 110.2 46.9 -59.9 -39.0 12.5 9.7 23.2 96 112 A K H X S+ 0 0 79 -4,-2.0 4,-2.4 2,-0.2 -2,-0.2 0.964 117.1 40.0 -70.1 -48.3 16.1 8.7 23.2 97 113 A S H X S+ 0 0 67 -4,-2.2 4,-2.2 1,-0.2 5,-0.2 0.927 117.6 48.5 -69.7 -39.2 15.7 5.0 22.4 98 114 A G H X S+ 0 0 6 -4,-2.9 4,-2.6 -5,-0.2 -1,-0.2 0.903 111.7 50.0 -65.9 -39.5 12.9 5.6 19.9 99 115 A T H X S+ 0 0 1 -4,-2.0 4,-2.9 -5,-0.4 5,-0.2 0.932 109.7 50.5 -63.6 -46.8 15.0 8.3 18.1 100 116 A K H X S+ 0 0 119 -4,-2.4 4,-2.0 1,-0.2 -2,-0.2 0.920 113.9 45.0 -58.7 -42.2 18.1 6.1 17.9 101 117 A A H X S+ 0 0 40 -4,-2.2 4,-2.4 2,-0.2 -1,-0.2 0.916 114.7 48.5 -69.0 -40.7 16.0 3.2 16.4 102 118 A F H X S+ 0 0 0 -4,-2.6 4,-2.4 2,-0.2 -2,-0.2 0.909 111.0 49.2 -63.8 -43.3 14.2 5.6 14.0 103 119 A M H X S+ 0 0 34 -4,-2.9 4,-2.3 2,-0.2 -1,-0.2 0.894 111.4 50.1 -64.8 -40.4 17.5 7.2 12.8 104 120 A E H X S+ 0 0 149 -4,-2.0 4,-1.3 -5,-0.2 -2,-0.2 0.930 112.7 47.5 -61.2 -47.2 19.0 3.8 12.2 105 121 A A H X>S+ 0 0 23 -4,-2.4 5,-2.5 1,-0.2 4,-0.9 0.844 112.1 49.9 -63.0 -37.9 15.8 2.8 10.2 106 122 A L H <5S+ 0 0 34 -4,-2.4 3,-0.5 3,-0.2 -2,-0.2 0.896 106.1 54.1 -66.4 -47.1 16.0 6.1 8.1 107 123 A Q H <5S+ 0 0 174 -4,-2.3 -1,-0.2 1,-0.2 -2,-0.2 0.821 108.2 52.4 -57.3 -33.2 19.7 5.7 7.2 108 124 A A H <5S- 0 0 94 -4,-1.3 -1,-0.2 -5,-0.2 -2,-0.2 0.796 135.8 -85.7 -71.0 -34.4 18.8 2.2 5.9 109 125 A G T <5S+ 0 0 57 -4,-0.9 -3,-0.2 -3,-0.5 -2,-0.1 0.388 77.2 143.1 140.2 2.5 15.9 3.7 3.7 110 126 A A < - 0 0 29 -5,-2.5 2,-0.2 -8,-0.1 -1,-0.1 -0.150 46.3-116.1 -65.5 163.5 12.8 4.0 5.9 111 127 A D > - 0 0 85 1,-0.1 3,-2.0 0, 0.0 -1,-0.1 -0.702 15.7-117.0-102.8 156.0 10.4 7.0 5.5 112 128 A I G > S+ 0 0 14 1,-0.3 3,-2.0 -2,-0.2 -1,-0.1 0.817 112.6 70.3 -58.1 -31.3 9.4 9.8 7.9 113 129 A S G 3 S+ 0 0 30 1,-0.3 3,-0.4 2,-0.1 -1,-0.3 0.678 89.0 63.3 -62.4 -17.3 5.8 8.4 7.7 114 130 A M G X + 0 0 67 -3,-2.0 3,-2.2 1,-0.2 4,-0.3 0.373 67.7 110.9 -87.6 3.8 7.1 5.3 9.7 115 131 A I G X > + 0 0 0 -3,-2.0 3,-1.8 1,-0.3 5,-1.1 0.771 67.1 63.9 -47.0 -38.9 7.9 7.4 12.8 116 132 A G G > 5S+ 0 0 32 -3,-0.4 3,-1.2 1,-0.3 -1,-0.3 0.690 89.2 67.0 -63.5 -22.8 5.1 5.9 14.9 117 133 A Q G < 5S+ 0 0 149 -3,-2.2 -1,-0.3 1,-0.2 -2,-0.2 0.615 100.1 53.1 -71.9 -10.7 6.7 2.4 14.7 118 134 A F G < 5S- 0 0 51 -3,-1.8 -1,-0.2 -4,-0.3 -2,-0.2 0.240 114.6-113.5-109.3 9.5 9.5 3.8 16.8 119 135 A G T < 5S+ 0 0 53 -3,-1.2 3,-0.2 1,-0.1 -3,-0.2 0.511 97.4 93.8 75.7 5.0 7.3 5.2 19.6 120 136 A V > < + 0 0 4 -5,-1.1 3,-1.9 -22,-0.2 4,-0.3 0.047 36.7 123.7-118.0 22.6 8.1 8.9 18.8 121 137 A G G > + 0 0 1 1,-0.3 3,-2.1 -6,-0.2 4,-0.3 0.767 61.9 75.7 -53.5 -27.9 5.2 9.7 16.5 122 138 A F G > S+ 0 0 39 1,-0.3 3,-2.1 -3,-0.2 -1,-0.3 0.876 86.6 62.6 -49.8 -40.7 4.3 12.6 18.8 123 139 A Y G X S+ 0 0 23 -3,-1.9 3,-1.8 1,-0.3 -1,-0.3 0.631 79.4 80.4 -67.9 -12.2 7.3 14.5 17.2 124 140 A S G X S+ 0 0 0 -3,-2.1 3,-2.2 1,-0.3 4,-0.4 0.691 73.4 82.0 -64.2 -13.4 5.6 14.4 13.8 125 141 A A G X> S+ 0 0 0 -3,-2.1 4,-2.1 -4,-0.3 3,-1.6 0.841 79.4 66.0 -56.6 -32.9 3.7 17.4 15.3 126 142 A Y G <4 S+ 0 0 1 -3,-1.8 -1,-0.3 1,-0.3 -2,-0.2 0.556 82.1 74.9 -71.5 -3.2 6.8 19.5 14.3 127 143 A L G <4 S+ 0 0 2 -3,-2.2 -1,-0.3 1,-0.1 -2,-0.2 0.826 119.7 12.4 -69.3 -30.5 6.0 18.8 10.6 128 144 A V T <4 S+ 0 0 0 -3,-1.6 47,-2.9 -4,-0.4 2,-0.4 0.591 117.3 74.1-120.9 -17.6 3.2 21.3 11.0 129 145 A A E < -E 174 0A 1 -4,-2.1 45,-0.3 45,-0.3 3,-0.1 -0.872 47.1-165.5-111.5 138.7 3.7 23.2 14.3 130 146 A E E S+ 0 0 113 43,-2.4 2,-0.3 -2,-0.4 44,-0.1 0.718 90.7 18.8 -82.5 -24.9 6.2 25.8 15.3 131 147 A K E -E 173 0A 65 42,-1.1 42,-2.7 -6,-0.1 2,-0.4 -0.990 68.4-158.9-146.2 141.9 5.3 25.2 18.9 132 148 A V E -EF 172 148A 0 16,-2.1 16,-2.0 -2,-0.3 2,-0.4 -0.996 5.5-168.4-125.5 131.1 3.6 22.3 20.7 133 149 A T E -EF 171 147A 11 38,-2.3 38,-3.5 -2,-0.4 2,-0.6 -0.976 3.9-162.6-118.7 127.5 1.9 22.7 24.1 134 150 A V E -EF 170 146A 5 12,-3.4 12,-2.7 -2,-0.4 2,-0.5 -0.957 3.9-171.6-114.3 117.8 0.8 19.5 26.0 135 151 A I E +EF 169 145A 14 34,-2.6 34,-2.9 -2,-0.6 2,-0.3 -0.925 21.3 170.8-104.4 126.9 -1.7 20.0 28.8 136 152 A T E -EF 168 144A 0 8,-2.6 8,-2.5 -2,-0.5 2,-0.4 -0.993 27.3-169.6-145.8 151.6 -2.1 16.8 30.7 137 153 A K E -E 167 0A 45 30,-2.9 30,-2.7 -2,-0.3 2,-0.3 -0.962 7.6-173.8-142.6 116.7 -3.7 15.3 33.8 138 154 A H > - 0 0 21 4,-0.5 3,-2.0 -56,-0.4 -57,-0.2 -0.820 37.0-116.4-104.0 148.8 -3.0 11.8 35.2 139 155 A N T 3 S+ 0 0 51 -59,-0.5 -58,-0.1 -2,-0.3 -1,-0.1 0.764 113.8 51.9 -53.3 -32.1 -5.0 10.5 38.1 140 156 A D T 3 S+ 0 0 130 2,-0.1 -1,-0.3 0, 0.0 2,-0.3 0.289 115.7 30.2 -92.6 10.2 -1.8 10.3 40.3 141 157 A D S < S- 0 0 49 -3,-2.0 2,-0.1 -58,-0.1 3,-0.0 -0.876 84.1 -87.8-153.6-179.3 -0.6 13.9 39.7 142 158 A E - 0 0 103 -2,-0.3 -4,-0.5 1,-0.1 2,-0.4 -0.313 56.3 -75.7 -93.0 176.2 -1.7 17.5 39.1 143 159 A Q - 0 0 19 16,-0.2 16,-2.6 -6,-0.2 2,-0.3 -0.645 56.2-175.4 -76.6 130.4 -2.4 19.2 35.7 144 160 A Y E -FG 136 158A 17 -8,-2.5 -8,-2.6 -2,-0.4 2,-0.5 -0.868 22.9-145.2-125.4 157.0 0.8 20.2 33.9 145 161 A A E -FG 135 157A 6 12,-2.8 12,-2.0 -2,-0.3 2,-0.4 -0.992 13.9-173.6-121.2 120.5 1.8 22.0 30.7 146 162 A W E +FG 134 156A 13 -12,-2.7 -12,-3.4 -2,-0.5 2,-0.3 -0.874 15.8 176.8-104.6 142.3 4.8 20.8 28.7 147 163 A E E +FG 133 155A 41 8,-2.1 8,-2.6 -2,-0.4 2,-0.3 -0.996 12.8 170.4-150.8 144.9 5.9 23.1 25.9 148 164 A S E -F 132 0A 4 -16,-2.0 -16,-2.1 -2,-0.3 6,-0.1 -0.945 26.4-176.3-156.8 137.5 8.6 23.3 23.2 149 165 A S - 0 0 73 1,-0.6 2,-0.1 4,-0.3 5,-0.1 -0.054 59.1-117.0-107.6 26.9 9.4 25.3 20.1 150 166 A A S > S+ 0 0 17 3,-0.3 3,-1.0 1,-0.1 -1,-0.6 -0.454 73.3 128.8 64.7-148.4 12.5 23.1 19.6 151 167 A G T 3 S- 0 0 86 1,-0.2 -1,-0.1 -140,-0.1 3,-0.1 0.675 101.6 -66.5 73.3 11.0 15.8 25.1 19.8 152 168 A G T 3 S+ 0 0 32 1,-0.2 -146,-2.2 -141,-0.1 2,-0.3 0.393 111.7 78.5 94.8 -0.8 17.1 22.5 22.3 153 169 A S E < -A 5 0A 49 -3,-1.0 -3,-0.3 -148,-0.3 -4,-0.3 -0.940 46.6-170.6-139.3 161.6 14.8 23.1 25.3 154 170 A F E -A 4 0A 17 -150,-2.2 -150,-3.1 -2,-0.3 2,-0.3 -0.944 16.6-138.1-141.5 162.2 11.3 22.5 26.7 155 171 A T E -AG 3 147A 21 -8,-2.6 -8,-2.1 -2,-0.3 2,-0.4 -0.887 9.2-166.2-122.0 155.8 9.4 23.8 29.7 156 172 A V E +AG 2 146A 2 -154,-2.1 -154,-2.5 -2,-0.3 2,-0.3 -0.995 18.2 157.4-136.6 133.7 7.2 22.2 32.3 157 173 A R E - G 0 145A 125 -12,-2.0 -12,-2.8 -2,-0.4 2,-0.2 -0.983 49.5 -93.8-146.5 158.5 4.9 24.0 34.7 158 174 A T E - G 0 144A 68 -2,-0.3 2,-0.5 -14,-0.2 -14,-0.3 -0.498 51.0-125.0 -68.2 137.4 1.8 23.3 36.8 159 175 A D - 0 0 37 -16,-2.6 -16,-0.2 -23,-0.2 -1,-0.1 -0.824 26.2-173.1 -95.7 129.6 -1.1 24.4 34.6 160 176 A T + 0 0 143 -2,-0.5 -1,-0.1 3,-0.0 -16,-0.0 0.260 53.1 111.5-100.4 7.9 -3.7 27.0 35.9 161 177 A G S S- 0 0 35 1,-0.2 3,-0.1 -18,-0.0 -18,-0.1 0.044 87.0 -43.4 -69.3-176.8 -5.9 26.6 32.8 162 178 A E S S- 0 0 157 1,-0.1 -1,-0.2 2,-0.1 2,-0.1 -0.276 73.1-107.6 -52.7 124.4 -9.4 25.0 32.8 163 179 A P - 0 0 103 0, 0.0 -1,-0.1 0, 0.0 3,-0.1 -0.342 29.9-159.3 -61.2 131.1 -9.2 21.8 34.9 164 180 A M - 0 0 33 1,-0.1 2,-2.0 3,-0.1 -27,-0.1 0.537 15.1-140.5 -87.6 -19.8 -9.4 18.7 32.7 165 181 A G S S- 0 0 37 -27,-0.1 2,-0.3 2,-0.1 -1,-0.1 -0.505 75.5 -24.2 88.7 -69.6 -10.5 15.8 34.9 166 182 A R S S+ 0 0 5 -2,-2.0 2,-0.3 -89,-0.1 -28,-0.2 -0.913 100.1 51.0-170.5 145.0 -8.1 13.4 33.1 167 183 A G E - E 0 137A 0 -30,-2.7 -30,-2.9 -2,-0.3 -85,-0.4 -0.852 68.3 -68.7 128.2-159.5 -6.3 13.2 29.8 168 184 A T E -DE 77 136A 9 -91,-1.6 -91,-2.8 -2,-0.3 2,-0.4 -0.996 18.8-161.4-143.7 143.6 -4.2 15.1 27.4 169 185 A K E -DE 76 135A 59 -34,-2.9 -34,-2.6 -2,-0.3 2,-0.7 -0.995 8.7-162.5-121.7 122.8 -4.5 18.1 25.1 170 186 A V E -DE 75 134A 12 -95,-2.7 -95,-2.4 -2,-0.4 2,-0.7 -0.941 11.1-162.2-105.2 110.5 -1.9 18.5 22.3 171 187 A I E -DE 74 133A 36 -38,-3.5 -38,-2.3 -2,-0.7 2,-0.7 -0.870 1.3-158.6 -99.2 116.8 -2.0 22.1 21.1 172 188 A L E -DE 73 132A 0 -99,-2.8 -99,-1.9 -2,-0.7 2,-1.1 -0.858 5.5-158.3 -98.4 111.2 -0.4 22.6 17.7 173 189 A H E -DE 72 131A 40 -42,-2.7 -43,-2.4 -2,-0.7 -42,-1.1 -0.806 33.8-135.9 -87.8 96.4 0.6 26.3 17.1 174 190 A L E - E 0 129A 0 -103,-2.0 -45,-0.3 -2,-1.1 5,-0.1 -0.276 5.7-111.3 -65.2 146.4 0.7 25.9 13.3 175 191 A K > - 0 0 35 -47,-2.9 3,-2.1 1,-0.1 -1,-0.1 -0.334 38.2-107.7 -64.6 153.0 3.4 27.2 11.0 176 192 A E G > S+ 0 0 152 1,-0.3 3,-0.5 2,-0.1 -1,-0.1 0.807 118.7 48.2 -58.5 -30.6 2.0 30.0 8.8 177 193 A D G 3 S+ 0 0 109 1,-0.2 -1,-0.3 2,-0.1 3,-0.2 0.238 100.5 69.1 -93.5 9.4 2.0 27.9 5.6 178 194 A Q G X + 0 0 13 -3,-2.1 3,-1.4 -50,-0.1 -1,-0.2 0.061 55.6 118.2-116.7 29.0 0.2 25.0 7.3 179 195 A T G X + 0 0 59 -3,-0.5 3,-2.1 1,-0.3 4,-0.2 0.595 53.1 86.1 -73.6 -8.7 -3.3 26.5 7.9 180 196 A E G > S+ 0 0 65 1,-0.3 3,-1.8 -3,-0.2 -1,-0.3 0.810 78.6 69.0 -58.3 -26.0 -5.0 23.9 5.7 181 197 A Y G < S+ 0 0 6 -3,-1.4 -1,-0.3 1,-0.3 -2,-0.1 0.424 91.7 59.2 -76.8 6.2 -5.1 21.8 8.9 182 198 A L G < S+ 0 0 8 -3,-2.1 2,-0.4 -116,-0.1 -1,-0.3 0.391 84.4 100.7-103.6 -7.8 -7.7 24.2 10.3 183 199 A E S <> S- 0 0 95 -3,-1.8 4,-2.5 -4,-0.2 3,-0.2 -0.713 71.0-139.3 -86.3 134.6 -10.1 23.6 7.5 184 200 A E H > S+ 0 0 112 -2,-0.4 4,-2.6 1,-0.2 5,-0.2 0.890 102.0 51.0 -55.6 -49.6 -13.0 21.2 8.2 185 201 A R H > S+ 0 0 218 1,-0.2 4,-2.1 2,-0.2 -1,-0.2 0.873 111.8 48.9 -59.6 -36.8 -12.8 19.5 4.8 186 202 A R H > S+ 0 0 40 -6,-0.3 4,-2.1 -3,-0.2 -2,-0.2 0.934 112.3 45.4 -70.4 -46.6 -9.1 18.9 5.2 187 203 A I H X S+ 0 0 1 -4,-2.5 4,-2.5 -7,-0.2 5,-0.2 0.936 113.2 50.6 -63.1 -43.8 -9.3 17.4 8.7 188 204 A K H X S+ 0 0 136 -4,-2.6 4,-2.3 -5,-0.2 -1,-0.2 0.914 110.1 51.5 -59.1 -42.5 -12.3 15.2 7.7 189 205 A E H X S+ 0 0 110 -4,-2.1 4,-2.1 -5,-0.2 -1,-0.2 0.915 111.9 45.7 -59.9 -45.3 -10.3 13.9 4.7 190 206 A I H X S+ 0 0 0 -4,-2.1 4,-2.3 2,-0.2 5,-0.4 0.901 112.4 49.2 -67.1 -43.4 -7.3 13.0 6.8 191 207 A V H X S+ 0 0 27 -4,-2.5 4,-2.6 2,-0.2 -2,-0.2 0.924 112.6 48.7 -63.0 -41.3 -9.3 11.3 9.6 192 208 A K H < S+ 0 0 155 -4,-2.3 4,-0.5 -5,-0.2 -2,-0.2 0.896 114.7 46.6 -64.8 -39.4 -11.2 9.2 6.9 193 209 A K H < S+ 0 0 125 -4,-2.1 -2,-0.2 -5,-0.2 -1,-0.2 0.877 132.4 10.5 -68.4 -43.8 -7.9 8.3 5.2 194 210 A H H < S+ 0 0 45 -4,-2.3 -3,-0.2 -5,-0.1 -2,-0.2 0.575 131.3 37.0-116.8 -18.5 -5.8 7.3 8.2 195 211 A S >< + 0 0 6 -4,-2.6 3,-1.2 -5,-0.4 -3,-0.2 0.115 68.5 119.2-131.7 26.1 -8.0 7.0 11.4 196 212 A Q T 3 S+ 0 0 103 -4,-0.5 -1,-0.1 1,-0.2 -4,-0.1 0.716 79.4 47.6 -67.9 -23.7 -11.4 5.6 10.3 197 213 A F T 3 S+ 0 0 185 -3,-0.1 -1,-0.2 -5,-0.0 2,-0.1 0.228 73.4 136.9-105.8 14.6 -11.1 2.5 12.5 198 214 A I < - 0 0 47 -3,-1.2 2,-0.3 1,-0.1 4,-0.1 -0.426 57.4-130.3 -62.8 133.2 -10.1 4.1 15.8 199 215 A G S S+ 0 0 59 -2,-0.1 -1,-0.1 2,-0.1 -3,-0.0 -0.018 82.5 66.7 -81.5 29.3 -12.1 2.5 18.7 200 216 A Y S S- 0 0 17 -2,-0.3 2,-0.2 -138,-0.0 -139,-0.2 -0.980 95.5 -91.0-145.0 148.6 -13.2 5.8 20.2 201 217 A P - 0 0 79 0, 0.0 -139,-2.6 0, 0.0 2,-0.6 -0.472 36.3-158.9 -67.0 127.1 -15.5 8.5 19.0 202 218 A I E -c 62 0A 45 -2,-0.2 2,-0.6 -141,-0.2 -139,-0.2 -0.952 6.4-163.7-106.8 112.0 -13.5 11.2 17.2 203 219 A T E -c 63 0A 70 -141,-2.5 -139,-2.9 -2,-0.6 2,-0.9 -0.901 7.7-154.5-102.9 119.7 -15.5 14.5 17.1 204 220 A L E -c 64 0A 44 -2,-0.6 -139,-0.2 -141,-0.2 2,-0.1 -0.808 18.5-150.5 -90.5 105.0 -14.3 17.1 14.6 205 221 A F - 0 0 83 -141,-2.8 2,-0.2 -2,-0.9 -142,-0.0 -0.435 10.6-155.5 -72.2 155.7 -15.3 20.4 16.1 206 222 A V 0 0 88 -2,-0.1 -23,-0.0 -141,-0.1 -1,-0.0 -0.743 360.0 360.0-125.3 171.9 -16.1 23.2 13.7 207 223 A E 0 0 157 -2,-0.2 -23,-0.1 -142,-0.0 -140,-0.1 -0.845 360.0 360.0-114.7 360.0 -16.1 27.0 14.0