==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=12-JUL-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 30-OCT-12 2YPC . COMPND 2 MOLECULE: 2', 3'-CYCLIC NUCLEOTIDE 3'-PHOSPHODIESTERASE; . SOURCE 2 ORGANISM_SCIENTIFIC: MUS MUSCULUS; . AUTHOR M.MYLLYKOSKI,A.RAASAKKA,M.LEHTIMAKI,H.HAN,P.KURSULA . 214 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 11954.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 147 68.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 55 25.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 3 1.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 15 7.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 28 13.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 42 19.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 3 1 1 0 0 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 0 1 0 2 3 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 163 A D 0 0 199 0, 0.0 2,-0.3 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 -66.0 17.7 7.2 38.6 2 164 A F - 0 0 131 1,-0.1 75,-0.2 75,-0.0 74,-0.1 -0.612 360.0-140.6 -98.5 147.3 15.0 4.9 37.1 3 165 A L - 0 0 23 73,-0.9 75,-0.1 -2,-0.3 -1,-0.1 -0.221 28.2 -83.2 -92.6 174.9 13.4 5.3 33.8 4 166 A P - 0 0 4 0, 0.0 72,-2.0 0, 0.0 73,-0.3 -0.181 39.0-107.7 -67.1 169.6 9.8 4.8 32.5 5 167 A L S S- 0 0 34 208,-2.7 70,-2.6 1,-0.3 69,-2.1 0.932 97.8 -25.4 -61.1 -45.9 8.3 1.5 31.5 6 168 A Y E -AB 73 213A 25 207,-1.3 207,-2.7 67,-0.3 -1,-0.3 -0.972 59.9-124.6-161.9 156.8 8.6 2.8 27.9 7 169 A F E +AB 72 212A 10 65,-2.3 64,-2.2 -2,-0.3 65,-0.8 -0.725 46.2 124.7 -96.5 156.6 8.8 6.0 25.9 8 170 A G E -AB 70 211A 0 203,-2.1 203,-2.5 62,-0.3 2,-0.6 -0.980 59.8 -71.8 174.6 179.7 6.4 6.7 23.0 9 171 A W E -AB 69 210A 0 60,-2.4 60,-2.5 -2,-0.3 2,-0.5 -0.886 41.0-155.8 -95.5 120.6 3.9 9.0 21.4 10 172 A F E -AB 68 209A 32 199,-3.0 199,-2.3 -2,-0.6 58,-0.2 -0.885 14.6-131.6-103.2 123.4 0.5 9.1 23.2 11 173 A L E - B 0 208A 4 56,-2.3 197,-0.3 -2,-0.5 55,-0.0 -0.383 23.3-109.4 -74.0 146.3 -2.5 10.1 21.1 12 174 A T > - 0 0 55 195,-1.7 4,-2.5 1,-0.1 55,-0.3 -0.213 36.4-101.3 -65.5 165.9 -4.9 12.7 22.3 13 175 A K H > S+ 0 0 173 1,-0.2 4,-2.1 2,-0.2 5,-0.2 0.915 123.7 48.1 -53.0 -43.5 -8.4 11.5 23.3 14 176 A K H > S+ 0 0 163 2,-0.2 4,-2.3 1,-0.2 -1,-0.2 0.947 113.8 42.2 -66.6 -53.0 -9.7 12.8 20.0 15 177 A S H > S+ 0 0 14 1,-0.2 4,-2.4 2,-0.2 5,-0.2 0.867 112.7 56.0 -62.4 -37.6 -7.1 11.2 17.7 16 178 A S H X S+ 0 0 6 -4,-2.5 4,-2.9 1,-0.2 5,-0.2 0.937 109.1 45.7 -60.5 -48.4 -7.2 8.0 19.7 17 179 A E H X S+ 0 0 63 -4,-2.1 4,-2.8 -5,-0.2 5,-0.3 0.913 110.2 53.8 -65.4 -41.7 -10.9 7.6 19.2 18 180 A T H X S+ 0 0 60 -4,-2.3 4,-1.9 1,-0.2 -1,-0.2 0.946 115.3 40.3 -56.4 -49.1 -10.7 8.5 15.4 19 181 A L H X S+ 0 0 0 -4,-2.4 4,-2.6 2,-0.2 -2,-0.2 0.898 113.8 52.2 -67.3 -44.0 -8.0 5.7 15.0 20 182 A R H X S+ 0 0 93 -4,-2.9 4,-2.5 1,-0.2 -2,-0.2 0.928 110.9 48.4 -56.9 -48.3 -9.7 3.2 17.3 21 183 A K H X S+ 0 0 103 -4,-2.8 4,-2.5 -5,-0.2 -1,-0.2 0.905 111.1 50.1 -60.3 -41.8 -13.0 3.6 15.4 22 184 A A H X S+ 0 0 4 -4,-1.9 4,-2.3 -5,-0.3 -1,-0.2 0.908 110.4 51.0 -63.0 -41.4 -11.2 3.2 12.0 23 185 A G H X S+ 0 0 3 -4,-2.6 4,-2.2 1,-0.2 -2,-0.2 0.917 110.4 48.0 -60.2 -47.0 -9.6 0.1 13.4 24 186 A Q H X S+ 0 0 76 -4,-2.5 4,-2.0 2,-0.2 -2,-0.2 0.900 109.7 52.2 -62.4 -43.0 -12.9 -1.4 14.5 25 187 A V H X S+ 0 0 58 -4,-2.5 4,-3.0 1,-0.2 5,-0.2 0.932 109.0 51.8 -58.6 -44.3 -14.5 -0.6 11.1 26 188 A F H X S+ 0 0 5 -4,-2.3 4,-3.5 1,-0.2 5,-0.3 0.929 108.0 50.4 -58.0 -48.5 -11.7 -2.4 9.4 27 189 A L H X S+ 0 0 19 -4,-2.2 4,-2.2 2,-0.2 28,-0.4 0.898 113.3 46.4 -56.8 -42.0 -12.1 -5.5 11.5 28 190 A E H X S+ 0 0 72 -4,-2.0 4,-1.2 2,-0.2 -2,-0.2 0.954 117.4 42.1 -68.6 -49.4 -15.8 -5.6 10.8 29 191 A E H X S+ 0 0 62 -4,-3.0 4,-0.5 2,-0.2 3,-0.3 0.905 114.9 50.4 -62.9 -43.5 -15.4 -5.0 7.1 30 192 A L H >< S+ 0 0 0 -4,-3.5 3,-1.3 -5,-0.2 6,-0.3 0.930 108.5 52.1 -63.9 -44.1 -12.4 -7.4 6.8 31 193 A G H 3< S+ 0 0 6 -4,-2.2 22,-0.2 -5,-0.3 -1,-0.2 0.774 111.0 48.3 -63.1 -27.8 -14.3 -10.2 8.6 32 194 A N H 3< S+ 0 0 94 -4,-1.2 2,-0.3 -3,-0.3 -1,-0.3 0.493 88.3 110.7 -89.5 -3.2 -17.2 -9.9 6.2 33 195 A H XX - 0 0 36 -3,-1.3 4,-2.5 -4,-0.5 3,-0.9 -0.549 68.5-136.5 -82.8 133.9 -15.1 -9.9 3.1 34 196 A K H 3> S+ 0 0 172 -2,-0.3 4,-2.1 1,-0.3 -1,-0.1 0.840 104.6 55.7 -53.7 -39.8 -15.3 -12.9 0.7 35 197 A A H 34 S+ 0 0 16 2,-0.2 4,-0.5 1,-0.2 -1,-0.3 0.838 110.7 44.0 -62.9 -36.0 -11.5 -12.9 0.3 36 198 A F H X4 S+ 0 0 3 -3,-0.9 3,-1.2 -6,-0.3 -2,-0.2 0.923 112.6 49.9 -77.1 -46.5 -10.9 -13.2 4.0 37 199 A K H >< S+ 0 0 94 -4,-2.5 3,-1.6 1,-0.3 4,-0.2 0.889 105.0 60.7 -57.2 -38.1 -13.6 -15.8 4.7 38 200 A K T 3< S+ 0 0 154 -4,-2.1 -1,-0.3 -5,-0.3 3,-0.2 0.761 108.7 43.0 -61.6 -25.3 -12.1 -17.8 1.8 39 201 A E T X S+ 0 0 50 -3,-1.2 3,-2.3 -4,-0.5 4,-0.5 0.165 73.6 120.3-108.9 17.6 -8.8 -18.0 3.7 40 202 A L G X> + 0 0 30 -3,-1.6 4,-2.6 1,-0.3 3,-2.1 0.851 69.6 61.8 -53.3 -38.5 -10.0 -18.8 7.2 41 203 A R G 34 S+ 0 0 177 1,-0.3 -1,-0.3 -3,-0.2 -2,-0.1 0.679 103.9 50.8 -66.8 -13.7 -8.1 -22.1 7.4 42 204 A H G <4 S+ 0 0 90 -3,-2.3 -1,-0.3 1,-0.0 -2,-0.2 0.482 114.4 45.0 -92.5 -7.3 -4.9 -20.0 7.1 43 205 A F T <4 S+ 0 0 5 -3,-2.1 2,-0.3 -4,-0.5 -2,-0.2 0.839 116.7 35.0-103.9 -51.1 -6.0 -17.7 9.9 44 206 A I < - 0 0 23 -4,-2.6 -1,-0.2 2,-0.1 150,-0.0 -0.767 62.3-162.1-105.0 155.8 -7.3 -20.0 12.6 45 207 A S + 0 0 124 -2,-0.3 2,-0.1 -3,-0.1 -4,-0.1 -0.116 57.9 72.8-133.2 36.4 -5.7 -23.4 13.2 46 208 A G S S- 0 0 42 0, 0.0 -2,-0.1 0, 0.0 0, 0.0 -0.363 98.0 -66.3-130.5-152.2 -8.3 -25.4 15.2 47 209 A D + 0 0 170 -2,-0.1 -2,-0.0 0, 0.0 0, 0.0 -0.105 67.9 156.0-102.6 33.5 -11.6 -27.1 14.9 48 210 A E - 0 0 94 1,-0.1 5,-0.0 2,-0.1 -4,-0.0 -0.223 43.0-112.0 -57.5 148.2 -13.7 -24.0 14.2 49 211 A P - 0 0 100 0, 0.0 -1,-0.1 0, 0.0 0, 0.0 -0.188 31.8 -95.8 -77.4 175.2 -16.9 -24.5 12.3 50 212 A K S S+ 0 0 213 2,-0.0 -2,-0.1 -2,-0.0 0, 0.0 0.569 93.1 111.2 -65.5 -8.7 -17.7 -23.4 8.7 51 213 A E S S- 0 0 143 1,-0.1 2,-0.3 0, 0.0 -3,-0.0 0.192 78.0 -82.9 -60.8 179.8 -19.3 -20.3 10.3 52 214 A K - 0 0 115 -20,-0.0 2,-0.5 -12,-0.0 -1,-0.1 -0.687 34.7-135.0 -90.3 142.7 -18.1 -16.7 10.2 53 215 A L - 0 0 44 -2,-0.3 2,-0.8 -22,-0.2 -16,-0.0 -0.841 8.9-142.2 -99.6 126.6 -15.5 -15.3 12.6 54 216 A E >> - 0 0 63 -2,-0.5 4,-1.8 1,-0.2 3,-0.5 -0.804 10.6-162.4 -88.2 110.8 -16.1 -11.9 14.2 55 217 A L H 3> S+ 0 0 1 -2,-0.8 4,-2.8 -28,-0.4 -1,-0.2 0.779 84.6 64.5 -70.1 -28.3 -12.7 -10.3 14.3 56 218 A V H 34 S+ 0 0 34 1,-0.2 -1,-0.2 2,-0.2 -28,-0.0 0.911 110.4 40.4 -59.6 -38.6 -13.6 -7.7 17.0 57 219 A S H X4 S+ 0 0 87 -3,-0.5 3,-0.7 1,-0.2 -2,-0.2 0.866 111.1 57.5 -76.2 -34.8 -14.1 -10.6 19.4 58 220 A Y H 3< S+ 0 0 56 -4,-1.8 2,-1.3 1,-0.3 96,-0.3 0.933 107.2 48.1 -61.0 -45.7 -11.0 -12.4 18.0 59 221 A F T 3< S+ 0 0 1 -4,-2.8 -1,-0.3 1,-0.2 94,-0.2 -0.430 76.5 151.1 -90.8 62.4 -8.9 -9.4 18.9 60 222 A G < + 0 0 33 -2,-1.3 2,-1.0 -3,-0.7 -1,-0.2 0.773 47.6 77.3 -69.2 -29.4 -10.4 -9.3 22.3 61 223 A K B +C 152 0A 89 91,-1.7 91,-1.7 -3,-0.3 -1,-0.1 -0.747 65.2 162.0 -87.3 103.4 -7.5 -7.7 24.1 62 224 A R - 0 0 141 -2,-1.0 89,-0.2 89,-0.2 88,-0.1 -0.858 49.8 -86.3-118.9 155.2 -7.5 -4.0 23.2 63 225 A P - 0 0 40 0, 0.0 4,-0.1 0, 0.0 -1,-0.0 -0.388 36.4-145.6 -55.1 132.0 -5.9 -0.9 24.7 64 226 A P S S+ 0 0 147 0, 0.0 3,-0.1 0, 0.0 2,-0.1 0.736 74.7 5.6 -76.8 -23.4 -8.3 0.3 27.4 65 227 A G S S- 0 0 52 1,-0.4 2,-0.0 -49,-0.0 0, 0.0 -0.082 114.8 -3.2-130.7-133.7 -7.6 4.0 26.9 66 228 A V - 0 0 69 1,-0.1 -1,-0.4 -2,-0.1 2,-0.1 -0.343 68.7-121.0 -69.0 150.9 -5.7 6.2 24.6 67 229 A L - 0 0 5 -55,-0.3 -56,-2.3 -3,-0.1 2,-0.3 -0.436 31.2-171.8 -86.0 162.3 -3.6 4.6 21.9 68 230 A H E -A 10 0A 52 -58,-0.2 81,-0.6 81,-0.2 2,-0.5 -0.977 25.7-130.7-151.3 162.2 0.2 5.1 21.6 69 231 A C E -A 9 0A 0 -60,-2.5 -60,-2.4 -2,-0.3 2,-0.2 -0.954 31.3-139.3-118.0 107.1 3.2 4.4 19.4 70 232 A T E +A 8 0A 47 -2,-0.5 77,-0.3 77,-0.4 -62,-0.3 -0.425 25.3 174.7 -68.5 133.7 6.0 2.9 21.3 71 233 A T E S+ 0 0 8 -64,-2.2 2,-0.4 1,-0.3 -63,-0.2 0.810 71.2 4.8 -95.5 -58.9 9.6 4.0 20.6 72 234 A K E -A 7 0A 14 -65,-0.8 -65,-2.3 55,-0.1 2,-0.6 -0.966 59.6-145.2-137.6 122.1 11.6 2.3 23.3 73 235 A F E +A 6 0A 108 -2,-0.4 -67,-0.3 -67,-0.2 -68,-0.1 -0.743 26.2 169.0 -83.6 121.9 10.6 -0.3 25.9 74 236 A C > > - 0 0 0 -69,-2.1 3,-2.2 -2,-0.6 5,-2.2 0.651 28.8-148.4-110.2 -23.2 12.8 0.5 28.9 75 237 A D G > 5S- 0 0 51 -70,-2.6 3,-2.2 1,-0.3 -70,-0.3 0.912 76.7 -58.9 45.4 48.9 11.3 -1.6 31.8 76 238 A Y G 3 5S- 0 0 67 -72,-2.0 -73,-0.9 1,-0.3 -1,-0.3 0.616 108.9 -44.7 61.0 16.2 12.4 1.2 34.2 77 239 A G G < 5S+ 0 0 22 -3,-2.2 6,-0.3 -73,-0.3 -1,-0.3 0.221 120.0 103.2 113.0 -12.4 16.0 0.6 33.1 78 240 A K T < 5 + 0 0 174 -3,-2.2 2,-0.2 -4,-0.2 -3,-0.2 0.732 61.1 90.5 -75.7 -22.5 16.1 -3.2 33.1 79 241 A A S > S+ 0 0 15 -4,-0.1 4,-2.6 -3,-0.1 -1,-0.3 0.368 91.2 119.4 83.8 -5.5 19.7 -0.2 25.7 82 244 A A H <> S+ 0 0 0 -3,-1.9 4,-2.5 2,-0.2 5,-0.2 0.925 76.0 44.7 -60.4 -49.7 17.2 1.7 27.9 83 245 A E H > S+ 0 0 83 -4,-0.4 4,-1.8 -6,-0.3 -1,-0.2 0.937 113.2 51.2 -62.0 -47.7 19.7 4.0 29.7 84 246 A E H 4 S+ 0 0 118 1,-0.2 4,-0.4 2,-0.2 -1,-0.2 0.916 112.7 46.7 -55.3 -46.5 21.5 4.7 26.4 85 247 A Y H >< S+ 0 0 4 -4,-2.6 3,-1.3 1,-0.2 6,-0.2 0.920 111.3 50.2 -60.4 -47.5 18.2 5.7 24.7 86 248 A A H 3< S+ 0 0 13 -4,-2.5 -1,-0.2 1,-0.3 -2,-0.2 0.761 103.4 59.0 -71.0 -26.1 17.0 7.9 27.6 87 249 A Q T 3< S+ 0 0 131 -4,-1.8 -1,-0.3 -5,-0.2 -2,-0.2 0.522 77.7 117.6 -81.5 -5.6 20.2 9.9 27.9 88 250 A Q <> - 0 0 78 -3,-1.3 4,-2.2 -4,-0.4 3,-0.3 -0.420 68.0-134.3 -64.3 133.0 20.0 11.1 24.2 89 251 A E H > S+ 0 0 156 1,-0.2 4,-3.3 2,-0.2 5,-0.3 0.889 106.2 55.1 -49.3 -46.0 19.6 14.9 23.9 90 252 A V H > S+ 0 0 19 2,-0.2 4,-2.0 1,-0.2 -1,-0.2 0.880 107.5 49.4 -63.8 -35.4 16.9 14.5 21.3 91 253 A V H > S+ 0 0 2 -3,-0.3 4,-1.0 -6,-0.2 -1,-0.2 0.960 114.7 43.9 -64.7 -50.8 14.9 12.3 23.7 92 254 A K H >< S+ 0 0 129 -4,-2.2 3,-0.5 1,-0.2 -2,-0.2 0.919 115.6 47.9 -59.2 -47.3 15.2 14.8 26.6 93 255 A R H 3< S+ 0 0 145 -4,-3.3 -1,-0.2 1,-0.2 -2,-0.2 0.874 114.3 46.5 -61.2 -37.8 14.5 17.8 24.3 94 256 A S H >< S+ 0 0 8 -4,-2.0 3,-2.6 -5,-0.3 116,-0.3 0.563 80.4 123.1 -83.9 -12.5 11.4 16.1 22.8 95 257 A Y T << S+ 0 0 90 -4,-1.0 116,-0.2 -3,-0.5 3,-0.1 -0.363 86.9 5.9 -55.2 113.5 10.0 15.0 26.1 96 258 A G T 3 S+ 0 0 43 114,-3.8 -1,-0.3 1,-0.3 2,-0.2 0.400 99.9 134.8 93.7 -2.3 6.5 16.4 26.3 97 259 A K < - 0 0 117 -3,-2.6 113,-2.5 113,-0.3 -1,-0.3 -0.484 55.2-115.5 -85.2 152.6 6.5 17.8 22.8 98 260 A A E +D 209 0A 78 111,-0.2 2,-0.3 -2,-0.2 111,-0.2 -0.604 37.3 170.3 -87.6 146.0 3.6 17.5 20.3 99 261 A F E -D 208 0A 14 109,-2.6 109,-2.4 -2,-0.3 2,-0.4 -0.924 29.1-127.5-144.4 164.7 4.0 15.5 17.1 100 262 A K E -D 207 0A 125 -2,-0.3 2,-0.5 107,-0.2 20,-0.3 -0.988 19.8-153.6-120.3 129.8 1.8 14.3 14.3 101 263 A L E -D 206 0A 0 105,-3.0 105,-2.5 -2,-0.4 2,-0.6 -0.894 9.5-140.6-106.0 131.4 1.9 10.6 13.3 102 264 A S E -DE 205 118A 16 16,-0.6 16,-3.0 -2,-0.5 2,-0.6 -0.788 10.9-157.0 -95.7 117.3 1.1 9.6 9.8 103 265 A I E +DE 204 117A 0 101,-3.4 101,-2.2 -2,-0.6 14,-0.2 -0.868 18.1 170.5 -95.2 117.1 -0.9 6.3 9.6 104 266 A S E + 0 0 16 12,-1.8 96,-1.7 -2,-0.6 2,-0.3 0.636 59.4 7.6-102.9 -16.9 -0.5 4.7 6.2 105 267 A A E -DE 199 116A 2 11,-0.8 11,-2.8 94,-0.2 2,-0.4 -0.992 53.2-139.3-163.1 151.9 -2.1 1.3 6.6 106 268 A L E -DE 198 115A 0 92,-2.0 92,-3.3 -2,-0.3 2,-0.3 -0.937 30.6-171.4-112.5 142.5 -4.1 -1.0 8.9 107 269 A F E -DE 197 114A 1 7,-2.6 7,-2.3 -2,-0.4 2,-0.3 -0.946 15.5-162.9-137.4 160.3 -3.2 -4.6 9.2 108 270 A V E +DE 196 113A 0 88,-2.4 88,-3.0 -2,-0.3 5,-0.2 -0.995 12.0 167.7-138.7 139.6 -4.4 -7.9 10.7 109 271 A T - 0 0 5 3,-2.2 86,-0.2 -2,-0.3 85,-0.1 -0.869 56.1 -90.7-135.5 174.8 -2.6 -11.2 11.4 110 272 A P S S+ 0 0 36 0, 0.0 3,-0.1 0, 0.0 84,-0.1 0.670 126.9 35.7 -60.7 -12.5 -3.6 -14.3 13.3 111 273 A K S S+ 0 0 99 1,-0.3 42,-3.0 41,-0.1 2,-0.3 0.802 120.1 15.4-107.4 -42.6 -1.9 -12.6 16.4 112 274 A T E - F 0 152A 0 40,-0.2 -3,-2.2 48,-0.1 2,-0.4 -0.920 47.2-146.4-139.2 159.6 -2.4 -8.8 16.2 113 275 A A E +EF 108 151A 4 38,-2.5 37,-2.9 -2,-0.3 38,-1.8 -0.997 41.6 148.3-123.5 129.0 -4.4 -5.9 14.7 114 276 A G E -EF 107 149A 1 -7,-2.3 -7,-2.6 -2,-0.4 2,-0.4 -0.864 43.7-111.8-151.9 179.0 -2.5 -2.7 14.2 115 277 A A E -EF 106 148A 0 33,-2.3 33,-2.1 -2,-0.3 2,-0.5 -0.988 29.3-129.8-122.8 129.9 -1.8 0.5 12.4 116 278 A Q E -EF 105 147A 31 -11,-2.8 -12,-1.8 -2,-0.4 -11,-0.8 -0.690 21.8-155.1 -77.5 127.5 1.4 1.2 10.4 117 279 A V E -E 103 0A 3 29,-2.1 2,-0.8 -2,-0.5 -14,-0.2 -0.880 5.7-154.9-105.1 133.9 3.1 4.5 11.3 118 280 A V E -E 102 0A 56 -16,-3.0 -16,-0.6 -2,-0.4 26,-0.1 -0.862 22.3-145.0-110.3 98.3 5.3 6.3 8.9 119 281 A L - 0 0 17 -2,-0.8 -18,-0.1 24,-0.3 2,-0.1 -0.308 6.5-126.1 -70.2 140.3 7.7 8.4 10.9 120 282 A T > - 0 0 60 -20,-0.3 4,-2.7 1,-0.1 5,-0.2 -0.292 33.2-103.1 -66.7 165.5 9.0 11.8 9.8 121 283 A D H > S+ 0 0 137 1,-0.2 4,-0.9 2,-0.2 -1,-0.1 0.893 125.7 51.4 -61.1 -37.6 12.7 12.4 9.8 122 284 A Q H >4 S+ 0 0 116 1,-0.2 3,-0.7 2,-0.2 4,-0.3 0.929 111.8 46.0 -64.9 -43.5 12.3 14.4 13.0 123 285 A E H >4 S+ 0 0 3 1,-0.2 3,-1.6 2,-0.2 -2,-0.2 0.829 102.1 64.7 -68.6 -33.5 10.4 11.5 14.6 124 286 A L H >< S+ 0 0 60 -4,-2.7 3,-1.5 1,-0.3 -1,-0.2 0.773 89.4 68.8 -61.3 -24.4 13.0 8.9 13.3 125 287 A Q T << S+ 0 0 106 -4,-0.9 -1,-0.3 -3,-0.7 -2,-0.2 0.817 98.1 51.7 -62.9 -27.0 15.5 10.7 15.6 126 288 A L T < S+ 0 0 0 -3,-1.6 -1,-0.3 -4,-0.3 -2,-0.2 0.364 86.2 103.8 -89.6 2.5 13.5 9.3 18.5 127 289 A W S < S- 0 0 44 -3,-1.5 -55,-0.1 -4,-0.2 -56,-0.1 -0.750 76.7-119.7 -88.0 128.8 13.6 5.7 17.2 128 290 A P - 0 0 15 0, 0.0 2,-0.4 0, 0.0 15,-0.2 -0.330 15.2-157.1 -67.2 148.7 16.1 3.5 19.1 129 291 A S + 0 0 99 -48,-0.1 2,-0.1 13,-0.1 4,-0.1 -0.844 29.6 179.4-119.9 90.5 19.0 1.9 17.3 130 292 A D - 0 0 34 -2,-0.4 3,-0.2 1,-0.1 -49,-0.1 -0.454 42.2-128.5 -91.1 162.9 19.8 -0.9 19.7 131 293 A L S S+ 0 0 188 1,-0.2 2,-0.9 -2,-0.1 -1,-0.1 0.799 107.6 59.3 -74.8 -29.4 22.4 -3.7 19.5 132 294 A D S S+ 0 0 91 -52,-0.1 -1,-0.2 2,-0.0 -2,-0.1 -0.760 75.1 158.4-102.7 86.0 19.5 -6.1 20.1 133 295 A K - 0 0 94 -2,-0.9 2,-0.1 -3,-0.2 5,-0.1 -0.763 51.5 -95.2-103.1 152.7 17.1 -5.5 17.2 134 296 A P > - 0 0 31 0, 0.0 3,-2.1 0, 0.0 4,-0.4 -0.497 34.3-126.1 -61.9 135.6 14.6 -8.0 15.9 135 297 A S G > S+ 0 0 109 1,-0.3 3,-2.1 2,-0.2 -2,-0.0 0.881 107.9 65.7 -48.7 -40.3 16.2 -9.9 13.1 136 298 A A G 3 S+ 0 0 28 1,-0.3 -1,-0.3 3,-0.1 34,-0.0 0.659 87.8 66.0 -62.0 -19.6 13.2 -8.9 10.9 137 299 A S G X S+ 0 0 25 -3,-2.1 3,-1.5 2,-0.1 2,-0.3 0.679 79.3 103.0 -76.2 -16.5 14.1 -5.1 11.0 138 300 A E T < S+ 0 0 115 -3,-2.1 -3,-0.0 -4,-0.4 0, 0.0 -0.505 83.6 21.0 -70.3 128.7 17.3 -5.9 9.1 139 301 A G T 3 S+ 0 0 50 1,-0.4 -1,-0.2 -2,-0.3 -2,-0.1 0.291 107.2 95.2 97.5 -8.3 17.1 -4.9 5.4 140 302 A L S < S- 0 0 25 -3,-1.5 -1,-0.4 1,-0.1 3,-0.1 -0.825 88.4 -85.8-112.2 154.4 14.2 -2.5 6.0 141 303 A P > - 0 0 89 0, 0.0 3,-1.5 0, 0.0 -1,-0.1 -0.242 58.4 -90.0 -51.6 140.8 14.4 1.3 6.6 142 304 A P T 3 S+ 0 0 111 0, 0.0 -13,-0.1 0, 0.0 -18,-0.0 -0.250 113.9 25.6 -48.4 136.6 15.0 2.3 10.2 143 305 A G T > S+ 0 0 10 -15,-0.2 3,-1.7 -3,-0.1 -24,-0.3 0.542 76.4 129.3 86.1 6.8 11.8 2.8 12.1 144 306 A S T < + 0 0 21 -3,-1.5 -27,-0.1 1,-0.3 25,-0.1 0.777 66.9 65.4 -62.9 -26.8 9.8 0.4 9.9 145 307 A R T 3 S+ 0 0 71 -29,-0.1 -1,-0.3 20,-0.1 20,-0.2 0.655 72.4 125.3 -67.8 -16.2 8.6 -1.3 13.0 146 308 A A < + 0 0 0 -3,-1.7 -29,-2.1 -29,-0.1 2,-0.3 -0.214 36.1 136.5 -57.2 125.7 6.7 1.9 14.1 147 309 A S E - F 0 116A 15 -77,-0.3 2,-0.4 -31,-0.2 -77,-0.4 -0.956 50.5-121.0-160.3 168.4 3.1 1.0 14.7 148 310 A V E - F 0 115A 0 -33,-2.1 -33,-2.3 -2,-0.3 2,-0.4 -0.997 29.2-130.3-122.9 129.4 0.0 1.4 17.0 149 311 A T E + F 0 114A 29 -81,-0.6 -35,-0.2 -2,-0.4 -81,-0.2 -0.674 28.6 171.3 -80.8 129.7 -1.5 -1.7 18.6 150 312 A L E - 0 0 25 -37,-2.9 2,-0.3 -2,-0.4 -36,-0.2 0.669 65.4 -20.7-108.3 -27.9 -5.3 -1.9 18.1 151 313 A G E - F 0 113A 1 -38,-1.8 -38,-2.5 -89,-0.2 -1,-0.4 -0.967 52.9-147.4-171.6 166.7 -5.9 -5.5 19.5 152 314 A C E -CF 61 112A 3 -91,-1.7 -91,-1.7 -2,-0.3 -40,-0.2 -0.991 28.1-106.9-140.0 144.9 -4.3 -8.8 20.3 153 315 A A > - 0 0 7 -42,-3.0 3,-2.2 -2,-0.3 -94,-0.1 -0.276 52.7 -91.2 -61.3 162.2 -5.3 -12.5 20.3 154 316 A A T 3 S+ 0 0 83 -96,-0.3 -1,-0.1 1,-0.3 -43,-0.0 0.792 123.3 34.1 -53.7 -42.8 -5.8 -14.0 23.8 155 317 A D T 3 S+ 0 0 132 2,-0.1 2,-0.3 -44,-0.0 -1,-0.3 0.111 98.7 106.8-102.5 23.7 -2.3 -15.4 24.3 156 318 A V < - 0 0 7 -3,-2.2 -4,-0.1 -45,-0.1 -95,-0.0 -0.778 61.6-136.0-106.2 145.7 -0.5 -12.6 22.4 157 319 A Q > - 0 0 115 -2,-0.3 3,-3.3 1,-0.1 4,-0.3 -0.811 23.7-119.4-100.7 140.6 1.6 -9.8 23.9 158 320 A P T > S+ 0 0 80 0, 0.0 3,-1.7 0, 0.0 4,-0.5 0.778 109.6 71.1 -52.0 -29.3 1.3 -6.2 22.5 159 321 A V T 3> S+ 0 0 84 1,-0.3 4,-1.2 2,-0.2 3,-0.4 0.769 82.8 73.4 -54.4 -24.2 4.9 -6.2 21.5 160 322 A Q H <> S+ 0 0 50 -3,-3.3 4,-2.9 1,-0.2 -1,-0.3 0.779 80.9 71.5 -65.5 -24.9 4.0 -8.7 18.8 161 323 A T H <> S+ 0 0 0 -3,-1.7 4,-2.4 -4,-0.3 -1,-0.2 0.952 99.5 44.5 -58.3 -51.9 2.3 -5.9 16.7 162 324 A G H > S+ 0 0 6 -4,-0.5 4,-2.2 -3,-0.4 -1,-0.2 0.924 114.5 50.4 -55.1 -45.4 5.6 -4.3 15.8 163 325 A L H X S+ 0 0 52 -4,-1.2 4,-1.7 1,-0.2 -1,-0.2 0.867 108.9 51.3 -65.2 -38.2 7.0 -7.7 15.0 164 326 A D H X S+ 0 0 16 -4,-2.9 4,-2.4 2,-0.2 -1,-0.2 0.898 108.5 52.2 -63.2 -43.1 4.1 -8.6 12.8 165 327 A L H X S+ 0 0 0 -4,-2.4 4,-2.6 1,-0.2 -2,-0.2 0.901 107.2 52.2 -61.4 -41.8 4.5 -5.3 10.9 166 328 A L H X S+ 0 0 0 -4,-2.2 4,-2.2 2,-0.2 -1,-0.2 0.910 110.1 48.9 -60.6 -41.3 8.1 -6.1 10.2 167 329 A D H X S+ 0 0 74 -4,-1.7 4,-1.9 2,-0.2 -2,-0.2 0.900 111.9 48.5 -65.8 -42.5 7.2 -9.5 8.9 168 330 A I H X S+ 0 0 0 -4,-2.4 4,-1.6 2,-0.2 -2,-0.2 0.903 112.2 49.2 -61.6 -41.3 4.5 -8.0 6.6 169 331 A L H < S+ 0 0 19 -4,-2.6 4,-0.4 2,-0.2 -2,-0.2 0.862 109.4 50.9 -71.6 -34.8 7.0 -5.4 5.3 170 332 A Q H >< S+ 0 0 62 -4,-2.2 3,-0.7 1,-0.2 -1,-0.2 0.882 108.0 55.1 -62.2 -40.8 9.7 -8.0 4.6 171 333 A Q H 3< S+ 0 0 104 -4,-1.9 -2,-0.2 1,-0.2 -1,-0.2 0.871 116.1 36.0 -60.8 -38.6 7.0 -9.9 2.7 172 334 A V T 3< 0 0 28 -4,-1.6 -1,-0.2 -5,-0.1 -2,-0.2 0.370 360.0 360.0 -99.6 7.6 6.3 -6.8 0.5 173 335 A K < 0 0 151 -3,-0.7 -3,-0.1 -4,-0.4 3,-0.1 -0.339 360.0 360.0 -57.7 360.0 9.9 -5.6 0.3 174 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 175 338 A S 0 0 128 0, 0.0 2,-0.2 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0-126.5 7.6 -6.6 -5.0 176 339 A Q - 0 0 84 -3,-0.1 -4,-0.1 0, 0.0 2,-0.0 -0.762 360.0-148.8-167.0 124.1 3.9 -6.2 -4.5 177 340 A G - 0 0 45 -2,-0.2 2,-0.2 1,-0.2 14,-0.0 -0.155 39.6 -74.1 -82.6-178.2 0.9 -8.1 -6.1 178 341 A E - 0 0 171 1,-0.1 12,-0.3 2,-0.0 -1,-0.2 -0.472 51.8 -98.7 -84.8 151.3 -2.5 -6.7 -6.9 179 342 A A - 0 0 31 -2,-0.2 10,-0.3 1,-0.1 -1,-0.1 -0.273 19.2-149.1 -67.4 151.1 -5.1 -6.0 -4.3 180 343 A V S S+ 0 0 69 8,-2.9 2,-0.3 1,-0.2 9,-0.2 0.525 73.7 2.8 -99.6 -8.7 -7.9 -8.5 -3.6 181 344 A G E -G 188 0A 13 7,-1.2 7,-3.0 -146,-0.0 2,-0.4 -0.985 61.6-121.6-165.7 168.2 -10.5 -6.0 -2.7 182 345 A E E -G 187 0A 116 -2,-0.3 5,-0.2 5,-0.2 16,-0.0 -0.992 22.7-174.3-122.3 126.3 -11.6 -2.4 -2.2 183 346 A L E > -G 186 0A 14 3,-3.2 3,-1.4 -2,-0.4 -157,-0.0 -0.774 44.0 -99.7-109.3 163.6 -12.8 -1.1 1.1 184 347 A P T 3 S+ 0 0 114 0, 0.0 3,-0.1 0, 0.0 -1,-0.0 0.805 122.7 43.2 -52.8 -34.0 -14.1 2.5 1.5 185 348 A R T 3 S- 0 0 118 1,-0.2 16,-2.6 16,-0.1 17,-0.5 0.520 126.4 -55.0 -94.8 -7.3 -10.8 3.8 2.9 186 349 A G E < S-GH 183 200A 1 -3,-1.4 -3,-3.2 14,-0.3 2,-0.2 -0.984 72.7 -33.3 162.9-168.2 -8.5 1.9 0.5 187 350 A K E -GH 182 199A 91 12,-1.2 12,-2.6 -2,-0.3 2,-0.5 -0.543 46.1-137.6 -86.3 143.5 -7.2 -1.2 -1.2 188 351 A L E -GH 181 198A 0 -7,-3.0 -8,-2.9 10,-0.2 -7,-1.2 -0.881 16.7-166.7-106.3 126.9 -7.0 -4.6 0.5 189 352 A Y E - H 0 197A 39 8,-2.9 8,-2.2 -2,-0.5 2,-0.6 -0.922 13.3-150.7-113.9 139.4 -4.1 -7.0 0.1 190 353 A S E + H 0 196A 46 -2,-0.4 6,-0.2 -12,-0.3 -13,-0.1 -0.929 15.0 178.9-105.5 110.5 -3.8 -10.6 1.1 191 354 A L E - 0 0 15 4,-2.2 5,-0.1 -2,-0.6 -1,-0.1 0.347 42.2-112.8 -98.0 8.9 -0.2 -11.4 2.0 192 355 A G E > S+ H 0 195A 30 3,-0.5 3,-1.8 1,-0.0 -1,-0.3 -0.008 90.0 64.2 80.9 164.9 -0.7 -15.1 2.9 193 356 A K T 3 S- 0 0 163 1,-0.3 3,-0.1 -3,-0.1 -1,-0.0 0.823 131.5 -55.3 49.8 40.5 -0.4 -16.9 6.2 194 357 A G T 3 S+ 0 0 4 1,-0.2 2,-0.4 -85,-0.1 -1,-0.3 0.600 102.2 137.4 79.4 11.1 -3.4 -15.0 7.7 195 358 A R E < +H 192 0A 16 -3,-1.8 -4,-2.2 -86,-0.2 -3,-0.5 -0.795 26.2 177.1-103.2 133.4 -1.9 -11.6 7.0 196 359 A W E -HD 190 108A 5 -88,-3.0 -88,-2.4 -2,-0.4 2,-0.4 -0.989 8.7-167.9-136.4 139.3 -4.0 -8.7 5.7 197 360 A M E -HD 189 107A 13 -8,-2.2 -8,-2.9 -2,-0.4 2,-0.6 -0.992 10.4-160.2-133.4 129.5 -3.2 -5.1 4.9 198 361 A L E -HD 188 106A 3 -92,-3.3 -92,-2.0 -2,-0.4 2,-0.7 -0.933 16.0-154.3-101.7 113.9 -5.5 -2.1 4.1 199 362 A S E -HD 187 105A 50 -12,-2.6 -12,-1.2 -2,-0.6 -94,-0.2 -0.821 19.7-129.0 -93.1 115.6 -3.5 0.6 2.4 200 363 A L E -H 186 0A 13 -96,-1.7 -14,-0.3 -2,-0.7 3,-0.2 -0.424 6.5-149.0 -70.8 132.6 -5.2 3.9 3.0 201 364 A T E S+ 0 0 113 -16,-2.6 2,-0.5 1,-0.3 -1,-0.1 0.903 95.9 31.8 -62.3 -42.4 -6.0 6.1 0.0 202 365 A K E S- 0 0 177 -17,-0.5 -1,-0.3 -3,-0.0 -2,-0.0 -0.978 93.9-124.8-117.2 122.4 -5.5 9.1 2.3 203 366 A K E - 0 0 129 -2,-0.5 2,-0.4 -3,-0.2 -99,-0.2 -0.333 25.2-127.6 -58.4 140.3 -3.0 8.8 5.2 204 367 A M E - D 0 103A 15 -101,-2.2 -101,-3.4 -185,-0.0 2,-0.5 -0.761 16.1-148.8 -89.2 139.7 -4.6 9.5 8.6 205 368 A E E - D 0 102A 107 -2,-0.4 2,-0.4 -103,-0.2 -103,-0.2 -0.947 14.1-171.5-110.2 123.2 -2.8 12.1 10.7 206 369 A V E - D 0 101A 1 -105,-2.5 -105,-3.0 -2,-0.5 2,-0.3 -0.944 18.2-132.7-114.2 132.3 -3.0 11.6 14.5 207 370 A K E + D 0 100A 131 -2,-0.4 -195,-1.7 -107,-0.2 2,-0.3 -0.629 36.2 162.7 -76.3 141.2 -1.8 14.2 17.1 208 371 A A E -BD 11 99A 2 -109,-2.4 -109,-2.6 -2,-0.3 2,-0.4 -0.963 33.3-127.7-155.2 164.0 0.3 12.8 19.9 209 372 A I E -BD 10 98A 63 -199,-2.3 -199,-3.0 -2,-0.3 2,-0.5 -0.982 22.5-131.0-121.2 131.3 2.7 13.8 22.7 210 373 A F E +B 9 0A 0 -113,-2.5 -114,-3.8 -2,-0.4 -113,-0.3 -0.703 53.5 119.9 -78.6 125.7 6.1 12.2 23.2 211 374 A T E -B 8 0A 43 -203,-2.5 -203,-2.1 -2,-0.5 2,-0.4 -0.920 57.9 -80.3-165.5-170.3 6.6 11.2 26.8 212 375 A G E -B 7 0A 13 -2,-0.3 2,-0.4 -205,-0.2 -205,-0.2 -0.891 29.0-146.3-115.0 137.5 7.2 8.3 29.2 213 376 A Y E -B 6 0A 104 -207,-2.7 -208,-2.7 -2,-0.4 -207,-1.3 -0.886 9.1-165.1-103.9 133.1 4.8 5.8 30.6 214 377 A Y 0 0 105 -2,-0.4 -2,-0.0 -210,-0.2 -211,-0.0 -0.970 360.0 360.0-117.6 128.6 5.0 4.4 34.2 215 378 A G 0 0 102 -2,-0.4 -1,-0.1 0, 0.0 -2,-0.0 0.661 360.0 360.0 -66.2 360.0 3.0 1.3 35.2