==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSFERASE 09-FEB-05 1YSR . COMPND 2 MOLECULE: SENSOR-TYPE HISTIDINE KINASE PRRB; . SOURCE 2 ORGANISM_SCIENTIFIC: MYCOBACTERIUM TUBERCULOSIS; . AUTHOR E.NOWAK,S.PANJIKAR,P.TUCKER,MYCOBACTERIUM TUBERCULOSIS STRUC . 410 6 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 18243.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 303 73.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 15 3.7 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 89 21.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 3 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 4 1.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 30 7.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 29 7.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 118 28.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 8 2.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 1 1 0 0 3 0 0 0 0 0 3 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 0 0 3 0 3 3 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 3 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 299 A D 0 0 179 0, 0.0 39,-0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 156.3 6.7 14.6 -9.9 2 300 A D + 0 0 146 2,-0.1 2,-0.3 39,-0.0 38,-0.1 0.043 360.0 127.5 -85.2 17.7 5.5 11.0 -9.1 3 301 A H + 0 0 42 38,-0.1 38,-0.2 36,-0.1 36,-0.0 -0.605 35.1 172.4 -81.1 138.3 7.9 11.5 -6.1 4 302 A V E -A 40 0A 64 36,-3.1 36,-2.8 -2,-0.3 34,-0.1 -0.829 43.0 -65.4-138.7 169.9 6.3 10.7 -2.7 5 303 A P E -A 39 0A 29 0, 0.0 2,-0.4 0, 0.0 34,-0.2 -0.391 52.4-171.2 -60.0 134.0 7.4 10.4 0.9 6 304 A V E -A 38 0A 6 32,-3.2 32,-2.3 177,-0.2 2,-1.1 -0.982 23.3-144.4-131.7 122.4 9.8 7.4 1.4 7 305 A D E > -A 37 0A 37 -2,-0.4 4,-2.2 30,-0.2 30,-0.2 -0.760 19.1-171.0 -81.7 99.4 11.0 6.1 4.7 8 306 A I H > S+ 0 0 1 28,-2.4 4,-2.5 -2,-1.1 -1,-0.2 0.841 81.3 56.0 -61.9 -37.1 14.4 5.1 3.5 9 307 A T H > S+ 0 0 10 27,-0.7 4,-2.0 2,-0.2 -1,-0.2 0.942 109.6 43.3 -64.1 -46.6 15.1 3.3 6.7 10 308 A D H > S+ 0 0 69 1,-0.2 4,-2.8 2,-0.2 5,-0.2 0.875 110.4 58.0 -65.3 -39.8 12.1 1.0 6.5 11 309 A L H X S+ 0 0 2 -4,-2.2 4,-2.6 1,-0.2 -2,-0.2 0.926 108.8 45.2 -53.8 -49.9 12.8 0.5 2.8 12 310 A L H X S+ 0 0 0 -4,-2.5 4,-2.5 2,-0.2 -1,-0.2 0.891 110.4 54.0 -59.2 -44.1 16.3 -0.9 3.7 13 311 A D H X S+ 0 0 63 -4,-2.0 4,-2.1 1,-0.2 -2,-0.2 0.945 113.8 42.2 -59.7 -47.4 14.8 -3.0 6.6 14 312 A R H X S+ 0 0 83 -4,-2.8 4,-2.7 1,-0.2 5,-0.2 0.878 111.9 54.5 -67.0 -40.4 12.4 -4.6 4.1 15 313 A A H X S+ 0 0 0 -4,-2.6 4,-2.5 -5,-0.2 -1,-0.2 0.896 110.2 46.2 -58.3 -41.9 15.0 -5.0 1.4 16 314 A A H X S+ 0 0 2 -4,-2.5 4,-2.3 2,-0.2 -2,-0.2 0.933 113.2 49.7 -70.2 -40.7 17.3 -6.9 3.8 17 315 A H H X S+ 0 0 117 -4,-2.1 4,-0.7 1,-0.2 -2,-0.2 0.927 114.7 44.0 -62.7 -46.0 14.4 -9.1 5.0 18 316 A D H >X S+ 0 0 21 -4,-2.7 4,-1.0 1,-0.2 3,-0.8 0.879 112.1 52.7 -65.9 -41.9 13.4 -10.0 1.4 19 317 A A H >X S+ 0 0 6 -4,-2.5 4,-2.5 1,-0.2 3,-0.6 0.883 101.1 60.5 -60.2 -42.1 17.0 -10.5 0.3 20 318 A A H 3< S+ 0 0 45 -4,-2.3 -1,-0.2 1,-0.3 6,-0.2 0.748 105.6 50.3 -57.7 -24.6 17.6 -13.0 3.1 21 319 A R H << S+ 0 0 212 -3,-0.8 -1,-0.3 -4,-0.7 -2,-0.2 0.738 112.9 44.0 -83.9 -27.5 14.8 -15.1 1.6 22 320 A I H << S+ 0 0 37 -4,-1.0 329,-0.3 -3,-0.6 -2,-0.2 0.798 114.1 50.1 -84.8 -32.1 16.2 -15.0 -1.9 23 321 A Y S >< S- 0 0 19 -4,-2.5 3,-1.8 -5,-0.1 -1,-0.2 -0.846 82.5-146.9-115.4 95.8 19.8 -15.7 -1.0 24 322 A P T 3 S+ 0 0 88 0, 0.0 3,-0.1 0, 0.0 -3,-0.1 -0.220 83.5 11.7 -62.5 144.2 20.1 -18.7 1.3 25 323 A D T 3 S+ 0 0 158 1,-0.2 2,-0.3 -5,-0.2 -5,-0.1 0.398 91.5 132.3 73.3 -15.1 22.9 -18.4 3.8 26 324 A L < - 0 0 16 -3,-1.8 2,-0.8 -6,-0.2 -1,-0.2 -0.631 52.1-145.3 -66.8 131.6 23.4 -14.7 3.0 27 325 A D E +b 64 0B 95 36,-2.5 38,-2.5 -2,-0.3 2,-0.4 -0.909 35.5 162.5 -96.9 105.0 23.7 -12.7 6.3 28 326 A V E +b 65 0B 15 -2,-0.8 2,-0.3 36,-0.2 38,-0.2 -0.996 2.8 146.9-133.1 133.7 22.0 -9.4 5.3 29 327 A S E -b 66 0B 42 36,-1.4 38,-2.8 -2,-0.4 2,-0.7 -0.991 48.0-103.4-159.6 158.3 20.6 -6.8 7.7 30 328 A L E -b 67 0B 36 -2,-0.3 38,-0.2 36,-0.2 3,-0.1 -0.875 39.4-134.3 -87.5 120.7 19.9 -3.2 8.3 31 329 A V - 0 0 42 36,-2.6 38,-0.3 -2,-0.7 -18,-0.0 -0.417 46.6 -72.9 -65.0 142.8 22.4 -1.8 10.8 32 330 A P S S+ 0 0 130 0, 0.0 -1,-0.2 0, 0.0 37,-0.1 -0.129 72.6 166.4 -45.5 121.0 20.8 0.3 13.6 33 331 A S - 0 0 31 -3,-0.1 37,-0.1 35,-0.1 3,-0.1 -0.995 39.0-108.8-142.3 148.3 19.8 3.6 11.8 34 332 A P - 0 0 32 0, 0.0 2,-0.4 0, 0.0 35,-0.1 -0.400 50.0 -93.7 -70.9 156.5 17.7 6.7 12.5 35 333 A T - 0 0 43 119,-0.1 2,-0.5 -26,-0.1 -28,-0.0 -0.574 46.0-168.2 -68.7 123.2 14.5 6.9 10.6 36 334 A C - 0 0 9 -2,-0.4 -28,-2.4 -3,-0.1 -27,-0.7 -0.961 7.1-166.8-119.9 121.8 15.1 9.0 7.5 37 335 A I E +A 7 0A 5 -2,-0.5 2,-0.3 -30,-0.2 -30,-0.2 -0.889 14.7 165.8-103.8 132.5 12.3 10.2 5.3 38 336 A I E -A 6 0A 1 -32,-2.3 -32,-3.2 -2,-0.5 2,-0.5 -0.750 40.1-110.7-126.3 174.7 13.0 11.7 1.8 39 337 A V E +A 5 0A 46 96,-0.3 2,-0.3 -2,-0.3 -36,-0.1 -0.964 66.6 110.0-106.4 129.8 10.8 12.4 -1.2 40 338 A G E S-A 4 0A 0 -36,-2.8 -36,-3.1 -2,-0.5 74,-0.0 -0.908 72.8 -64.3-174.4-168.8 11.6 10.0 -3.9 41 339 A L > - 0 0 39 -2,-0.3 4,-2.9 -38,-0.2 5,-0.3 -0.910 36.5-162.4-112.0 104.7 10.4 7.1 -6.0 42 340 A P H > S+ 0 0 55 0, 0.0 4,-2.2 0, 0.0 5,-0.2 0.841 88.5 50.1 -63.5 -32.8 10.0 4.1 -3.8 43 341 A A H > S+ 0 0 19 2,-0.2 4,-2.4 1,-0.2 241,-0.2 0.940 114.6 44.8 -68.0 -40.3 10.1 1.5 -6.6 44 342 A G H > S+ 0 0 2 2,-0.2 4,-2.2 1,-0.2 -1,-0.2 0.911 114.2 48.7 -70.9 -41.9 13.3 3.0 -8.1 45 343 A L H X S+ 0 0 4 -4,-2.9 4,-2.2 1,-0.2 -1,-0.2 0.937 113.3 47.3 -64.0 -44.1 15.0 3.3 -4.7 46 344 A R H X S+ 0 0 7 -4,-2.2 4,-2.9 -5,-0.3 -1,-0.2 0.907 110.8 51.8 -61.9 -43.5 14.2 -0.2 -3.7 47 345 A L H X S+ 0 0 0 -4,-2.4 4,-3.0 2,-0.2 -1,-0.2 0.896 106.8 52.8 -59.8 -41.2 15.3 -1.5 -7.1 48 346 A A H X S+ 0 0 2 -4,-2.2 4,-2.2 2,-0.2 -2,-0.2 0.932 113.2 45.0 -57.8 -48.2 18.7 0.3 -6.7 49 347 A V H X S+ 0 0 3 -4,-2.2 4,-2.6 2,-0.2 -2,-0.2 0.923 112.7 50.5 -63.0 -47.1 19.2 -1.4 -3.3 50 348 A D H X S+ 0 0 31 -4,-2.9 4,-2.4 1,-0.2 -2,-0.2 0.905 111.2 48.8 -54.4 -45.8 18.1 -4.7 -4.7 51 349 A N H X S+ 0 0 1 -4,-3.0 4,-2.5 2,-0.2 -1,-0.2 0.866 109.4 52.0 -64.5 -42.0 20.5 -4.4 -7.6 52 350 A A H X S+ 0 0 6 -4,-2.2 4,-2.1 2,-0.2 -2,-0.2 0.931 112.0 46.7 -62.5 -46.2 23.4 -3.5 -5.1 53 351 A I H X S+ 0 0 2 -4,-2.6 4,-2.2 2,-0.2 5,-0.2 0.931 112.2 50.9 -60.3 -42.2 22.6 -6.6 -3.0 54 352 A A H X>S+ 0 0 1 -4,-2.4 4,-3.2 1,-0.2 5,-0.5 0.910 110.5 47.7 -65.7 -38.0 22.5 -8.8 -6.1 55 353 A N H X>S+ 0 0 4 -4,-2.5 5,-1.5 2,-0.2 4,-1.4 0.894 110.0 52.9 -68.2 -38.6 25.7 -7.6 -7.4 56 354 A A H <5S+ 0 0 5 -4,-2.1 6,-2.8 3,-0.2 4,-0.3 0.943 120.7 33.2 -61.9 -41.4 27.4 -8.1 -4.0 57 355 A V H X5S+ 0 0 19 -4,-2.2 4,-0.9 4,-0.2 -2,-0.2 0.971 124.3 39.2 -82.0 -53.6 26.2 -11.7 -3.9 58 356 A K H <5S+ 0 0 61 -4,-3.2 -3,-0.2 -5,-0.2 -2,-0.1 0.900 134.6 17.4 -71.7 -38.5 26.2 -12.8 -7.5 59 357 A H T < - C 0 75B 61 3,-2.6 3,-0.7 -2,-0.3 90,-0.1 -0.865 58.3 -91.2-148.7 176.7 22.1 15.0 8.0 73 371 A R T 3 S+ 0 0 114 89,-0.3 65,-0.2 -2,-0.3 63,-0.2 0.854 126.3 57.8 -61.5 -30.6 20.7 18.4 7.2 74 372 A A T 3 S- 0 0 78 1,-0.2 62,-1.7 61,-0.1 2,-0.4 0.687 120.3-101.4 -74.8 -23.3 21.8 17.6 3.6 75 373 A G E < -CD 72 135B 7 -3,-0.7 -3,-2.6 60,-0.3 2,-0.4 -0.997 58.6 -32.2 141.3-129.5 19.7 14.5 3.3 76 374 A V E -CD 71 134B 6 58,-2.7 58,-2.6 -2,-0.4 2,-0.6 -0.958 30.0-152.6-134.4 149.2 20.7 10.9 3.6 77 375 A E E -CD 70 133B 56 -7,-2.3 -7,-2.2 -2,-0.4 2,-0.4 -0.985 20.3-167.4-117.3 113.3 23.7 8.7 2.8 78 376 A I E -CD 69 132B 4 54,-2.7 54,-2.9 -2,-0.6 2,-0.4 -0.877 7.0-168.9 -98.1 135.0 22.6 5.1 2.2 79 377 A A E -CD 68 131B 1 -11,-2.4 -11,-1.9 -2,-0.4 2,-0.6 -0.989 20.1-163.6-130.8 139.8 25.4 2.5 2.1 80 378 A I E -CD 67 130B 4 50,-2.4 50,-2.8 -2,-0.4 2,-0.4 -0.978 21.5-172.8-117.9 103.3 25.4 -1.2 1.0 81 379 A D E -CD 66 129B 10 -15,-3.0 -15,-2.2 -2,-0.6 2,-0.3 -0.858 4.1-177.7 -96.7 137.5 28.5 -2.7 2.6 82 380 A D E -C 65 0B 11 46,-2.4 45,-2.5 -2,-0.4 -17,-0.2 -0.906 34.7-137.6-135.9 165.7 29.6 -6.3 1.7 83 381 A N S S+ 0 0 53 -19,-1.7 -18,-0.1 -2,-0.3 -2,-0.0 0.018 70.7 111.2-106.7 21.0 32.4 -8.8 2.6 84 382 A G S S- 0 0 13 -20,-0.2 -23,-0.2 44,-0.2 -24,-0.1 0.136 89.6 -67.3 -79.7-163.7 32.9 -9.9 -1.1 85 383 A S S S- 0 0 107 -25,-1.8 -24,-0.1 -29,-0.2 -25,-0.1 0.710 70.1-145.8 -58.6 -30.0 35.8 -9.4 -3.6 86 384 A G - 0 0 23 -30,-0.1 42,-0.2 42,-0.1 -1,-0.2 -0.270 17.8 -83.8 84.3 178.0 35.3 -5.7 -3.8 87 385 A V - 0 0 10 40,-0.2 5,-0.1 34,-0.2 -1,-0.1 -0.991 45.3-116.8-125.7 119.1 35.8 -3.4 -6.8 88 386 A P > - 0 0 75 0, 0.0 3,-2.9 0, 0.0 4,-0.5 -0.251 27.4-112.6 -56.2 143.9 39.4 -2.3 -7.3 89 387 A E G > S+ 0 0 155 1,-0.3 3,-0.7 2,-0.2 31,-0.1 0.824 116.8 53.3 -44.7 -39.6 39.8 1.5 -7.0 90 388 A G G 3 S+ 0 0 81 1,-0.2 -1,-0.3 2,-0.1 4,-0.2 0.502 106.0 55.0 -75.4 -2.6 40.6 1.8 -10.8 91 389 A E G <> S+ 0 0 106 -3,-2.9 4,-1.9 2,-0.1 -1,-0.2 0.416 73.6 97.6-113.0 -0.1 37.5 -0.0 -11.8 92 390 A R H <> S+ 0 0 58 -3,-0.7 4,-2.4 -4,-0.5 5,-0.2 0.926 83.2 49.5 -63.0 -47.2 34.6 1.9 -10.2 93 391 A Q H > S+ 0 0 144 1,-0.2 4,-1.6 2,-0.2 -1,-0.2 0.932 110.2 50.0 -59.5 -46.9 33.6 4.1 -13.1 94 392 A V H 4 S+ 0 0 72 1,-0.2 4,-0.4 2,-0.2 -1,-0.2 0.888 109.2 53.5 -60.8 -35.4 33.4 1.2 -15.6 95 393 A V H >< S+ 0 0 3 -4,-1.9 9,-2.0 1,-0.2 3,-1.4 0.950 109.1 47.7 -66.4 -43.1 31.3 -0.7 -13.1 96 394 A F H 3< S+ 0 0 29 -4,-2.4 -1,-0.2 1,-0.3 -2,-0.2 0.746 106.8 57.6 -67.3 -23.7 28.8 2.3 -12.8 97 395 A E T 3< S+ 0 0 126 -4,-1.6 2,-0.4 -5,-0.2 -1,-0.3 0.480 100.2 76.5 -83.9 -3.3 28.7 2.6 -16.6 98 396 A R S < S- 0 0 116 -3,-1.4 7,-2.7 -4,-0.4 6,-0.3 -0.892 72.3-136.1-113.8 142.8 27.5 -1.1 -16.9 99 397 A F 0 0 135 -2,-0.4 5,-0.2 5,-0.2 316,-0.1 -0.660 360.0 360.0 -86.9 144.5 24.1 -2.8 -16.3 100 398 A S 0 0 50 3,-0.5 -1,-0.1 -2,-0.3 4,-0.0 -0.476 360.0 360.0 -73.0 360.0 24.4 -6.1 -14.4 101 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 102 410 A L 0 0 61 0, 0.0 2,-0.4 0, 0.0 -4,-0.1 0.000 360.0 360.0 360.0 121.3 29.4 -6.6 -12.1 103 411 A G + 0 0 0 -52,-0.1 -3,-0.5 312,-0.1 -7,-0.2 -0.990 360.0 172.6-150.3 125.1 27.2 -3.6 -13.2 104 412 A L > + 0 0 5 -9,-2.0 4,-2.0 -2,-0.4 3,-0.3 0.004 42.3 119.6-120.8 22.5 25.7 -0.9 -11.1 105 413 A A H > S+ 0 0 10 -7,-2.7 4,-2.5 -10,-0.4 -6,-0.2 0.790 74.7 59.1 -61.0 -30.1 24.3 1.5 -13.8 106 414 A L H > S+ 0 0 19 -8,-0.2 4,-2.3 2,-0.2 -1,-0.2 0.915 105.8 49.5 -63.2 -42.8 20.7 1.0 -12.4 107 415 A V H > S+ 0 0 0 -3,-0.3 4,-2.5 2,-0.2 -2,-0.2 0.945 111.6 47.0 -59.8 -52.1 21.9 2.3 -9.1 108 416 A A H X S+ 0 0 12 -4,-2.0 4,-2.5 1,-0.2 -2,-0.2 0.913 110.1 54.2 -57.3 -41.3 23.6 5.4 -10.8 109 417 A Q H X S+ 0 0 84 -4,-2.5 4,-2.2 1,-0.2 -1,-0.2 0.921 110.8 45.1 -58.6 -49.6 20.4 6.0 -12.8 110 418 A Q H X S+ 0 0 3 -4,-2.3 4,-1.4 2,-0.2 -1,-0.2 0.916 111.0 53.4 -61.9 -41.4 18.2 6.1 -9.7 111 419 A A H <>S+ 0 0 0 -4,-2.5 5,-3.0 1,-0.2 3,-0.4 0.936 110.5 47.5 -58.4 -44.6 20.7 8.3 -7.8 112 420 A Q H ><5S+ 0 0 120 -4,-2.5 3,-2.4 1,-0.2 -2,-0.2 0.918 105.8 57.5 -66.0 -40.8 20.7 10.8 -10.6 113 421 A L H 3<5S+ 0 0 94 -4,-2.2 -1,-0.2 1,-0.3 -2,-0.2 0.773 109.8 47.3 -59.6 -26.2 16.8 10.8 -10.8 114 422 A H T 3<5S- 0 0 16 -4,-1.4 -1,-0.3 -3,-0.4 -2,-0.2 0.276 119.6-111.5 -97.2 8.9 16.9 11.8 -7.1 115 423 A G T < 5S+ 0 0 60 -3,-2.4 -3,-0.2 1,-0.2 2,-0.2 0.803 84.7 101.2 66.8 26.6 19.5 14.5 -7.7 116 424 A G < - 0 0 12 -5,-3.0 2,-0.3 -6,-0.2 -1,-0.2 -0.525 66.2-107.2-125.3-161.4 22.2 12.7 -5.8 117 425 A T E -E 133 0B 73 16,-1.8 16,-2.9 -2,-0.2 2,-0.4 -0.896 9.2-149.3-134.2 153.4 25.2 10.5 -6.5 118 426 A A E +E 132 0B 18 -2,-0.3 2,-0.3 14,-0.2 14,-0.2 -0.985 28.6 161.8-117.7 137.5 26.2 6.8 -6.3 119 427 A S E -E 131 0B 37 12,-2.1 12,-3.0 -2,-0.4 2,-0.4 -0.976 31.7-119.9-148.4 166.6 29.9 5.9 -5.7 120 428 A L E +E 130 0B 9 -2,-0.3 2,-0.3 10,-0.2 10,-0.2 -0.873 29.5 166.1-113.3 142.1 32.1 3.0 -4.6 121 429 A E E -E 129 0B 65 8,-2.4 8,-2.0 -2,-0.4 2,-0.4 -0.778 44.9 -86.8-136.9 175.0 34.4 2.9 -1.5 122 430 A N E -E 128 0B 114 -2,-0.3 6,-0.2 6,-0.2 5,-0.1 -0.793 46.6-130.6 -92.4 135.8 36.2 0.1 0.3 123 431 A S > - 0 0 12 4,-2.0 3,-1.6 -2,-0.4 6,-0.1 -0.636 10.9-133.2 -89.4 147.3 34.1 -1.5 3.0 124 432 A P T 3 S+ 0 0 120 0, 0.0 -1,-0.1 0, 0.0 -41,-0.1 0.704 111.1 63.5 -58.8 -20.1 35.1 -2.1 6.6 125 433 A L T 3 S- 0 0 45 -43,-0.2 3,-0.1 3,-0.1 -61,-0.0 0.602 121.9-106.8 -79.1 -14.8 33.6 -5.6 5.8 126 434 A G S < S+ 0 0 56 -3,-1.6 -43,-0.2 1,-0.3 3,-0.1 0.060 90.7 62.1 118.7 -28.3 36.2 -6.3 3.2 127 435 A G S S- 0 0 1 -45,-2.5 -4,-2.0 1,-0.3 -1,-0.3 0.327 96.9 -30.4-106.2-134.1 34.3 -6.0 -0.1 128 436 A A E - 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