==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER IMMUNE SYSTEM/TRANSFERASE 24-FEB-05 1YY9 . COMPND 2 MOLECULE: EPIDERMAL GROWTH FACTOR RECEPTOR; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR S.LI,K.R.SCHMITZ,P.D.JEFFREY,J.J.W.WILTZIUS,P.KUSSIE,K.M.FER . 1044 3 29 29 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 49681.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 643 61.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 97 9.3 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 227 21.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 7 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 10 1.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 8 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 2 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 3 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 107 10.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 109 10.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 36 3.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 7 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 1 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 12 9 3 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 13 9 9 4 7 6 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 4 3 6 3 4 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 2 A E 0 0 161 0, 0.0 2,-0.1 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 151.2 17.3 -1.7 13.6 2 3 A E - 0 0 88 0, 0.0 0, 0.0 0, 0.0 0, 0.0 -0.536 360.0-106.3-163.0 86.9 18.8 1.7 14.4 3 4 A K - 0 0 39 1,-0.1 2,-0.3 -2,-0.1 30,-0.1 0.332 26.5-120.8 -35.5 129.3 22.5 1.6 13.5 4 5 A K - 0 0 142 28,-0.2 30,-2.1 1,-0.0 31,-2.1 -0.556 30.7-152.2 -68.7 134.4 25.1 1.4 16.4 5 6 A V E -a 35 0A 58 -2,-0.3 2,-0.2 29,-0.2 31,-0.2 -0.921 12.5-171.3-118.4 124.1 27.4 4.4 16.2 6 7 A a E -a 36 0A 15 29,-2.4 31,-2.1 -2,-0.5 32,-0.3 -0.733 28.0-120.9-111.6 170.2 31.0 4.5 17.4 7 8 A Q - 0 0 59 -2,-0.2 31,-0.8 1,-0.2 2,-0.2 0.885 39.7-140.2 -74.3 -43.3 33.3 7.4 17.8 8 9 A G - 0 0 7 30,-0.2 2,-0.3 29,-0.2 -1,-0.2 -0.543 14.8-105.9 98.1-177.6 36.3 6.5 15.6 9 10 A T - 0 0 31 30,-1.6 30,-0.4 -2,-0.2 3,-0.1 -0.982 17.9-167.3-147.6 148.4 39.9 7.1 16.3 10 11 A S + 0 0 84 -2,-0.3 30,-0.0 28,-0.1 -2,-0.0 -0.229 49.2 118.5-134.2 56.2 42.7 9.4 15.1 11 12 A N > - 0 0 59 1,-0.2 3,-2.5 3,-0.1 -1,-0.1 0.474 48.5-169.4 -91.0 -2.2 46.0 8.0 16.5 12 13 A K T 3 - 0 0 99 1,-0.3 -1,-0.2 -3,-0.1 55,-0.1 -0.196 69.5 -12.7 45.2-125.0 47.5 7.4 13.0 13 14 A L T 3 S+ 0 0 63 2,-0.1 -1,-0.3 30,-0.0 2,-0.1 0.397 105.5 119.8 -87.8 5.5 50.6 5.4 13.3 14 15 A T < - 0 0 92 -3,-2.5 2,-0.5 1,-0.1 -3,-0.1 -0.370 56.1-139.9 -69.2 148.1 50.9 5.8 17.1 15 16 A Q - 0 0 67 -2,-0.1 2,-1.9 29,-0.0 4,-0.1 -0.918 3.2-143.1-121.4 113.5 50.8 2.6 19.2 16 17 A L - 0 0 75 -2,-0.5 2,-0.2 3,-0.1 9,-0.2 -0.460 60.2 -68.2 -77.2 78.7 48.9 2.6 22.5 17 18 A G S S+ 0 0 46 -2,-1.9 2,-0.0 4,-0.1 3,-0.0 -0.526 104.9 10.3 81.8-141.5 51.2 0.4 24.7 18 19 A T S > S- 0 0 79 -2,-0.2 4,-3.6 1,-0.1 5,-0.2 -0.350 72.9-115.6 -68.4 150.8 51.6 -3.4 24.0 19 20 A F H > S+ 0 0 82 2,-0.2 4,-2.5 1,-0.2 5,-0.2 0.928 125.8 53.8 -42.4 -49.0 50.3 -4.9 20.8 20 21 A E H > S+ 0 0 88 1,-0.2 4,-2.0 2,-0.2 -1,-0.2 0.963 110.8 42.1 -50.6 -61.7 48.1 -6.6 23.3 21 22 A D H > S+ 0 0 84 1,-0.2 4,-1.6 2,-0.2 -2,-0.2 0.867 112.1 56.0 -52.4 -44.3 47.0 -3.3 24.9 22 23 A H H X S+ 0 0 9 -4,-3.6 4,-1.9 1,-0.2 3,-0.5 0.950 109.5 44.3 -57.0 -55.1 46.5 -1.7 21.5 23 24 A F H X S+ 0 0 17 -4,-2.5 4,-3.4 1,-0.2 5,-0.3 0.858 106.5 60.8 -58.6 -42.1 44.1 -4.4 20.2 24 25 A L H X S+ 0 0 63 -4,-2.0 4,-2.2 -5,-0.2 -1,-0.2 0.906 110.8 40.2 -56.1 -39.0 42.1 -4.5 23.4 25 26 A S H X S+ 0 0 34 -4,-1.6 4,-2.5 -3,-0.5 -1,-0.2 0.797 111.9 55.6 -84.0 -28.8 41.2 -0.8 22.9 26 27 A L H X S+ 0 0 12 -4,-1.9 4,-2.7 2,-0.2 5,-0.3 0.963 112.7 43.5 -58.2 -53.8 40.7 -1.2 19.2 27 28 A Q H X S+ 0 0 73 -4,-3.4 4,-2.8 1,-0.2 -2,-0.2 0.898 111.7 54.6 -56.7 -44.1 38.2 -3.9 20.1 28 29 A R H < S+ 0 0 183 -4,-2.2 -1,-0.2 -5,-0.3 -2,-0.2 0.912 112.9 42.4 -58.8 -43.9 36.8 -1.7 22.8 29 30 A M H < S+ 0 0 62 -4,-2.5 -2,-0.2 1,-0.2 -1,-0.2 0.962 125.6 30.0 -67.1 -54.4 36.1 1.1 20.4 30 31 A F H >< S+ 0 0 1 -4,-2.7 3,-3.3 -5,-0.2 -2,-0.2 0.618 78.0 129.9 -89.1 -11.6 34.7 -0.9 17.4 31 32 A N T 3< S- 0 0 87 -4,-2.8 23,-0.1 1,-0.3 22,-0.0 -0.145 93.6 -6.0 -44.5 128.2 33.0 -3.9 19.1 32 33 A N T 3 S+ 0 0 100 1,-0.2 -1,-0.3 21,-0.2 -28,-0.2 0.442 96.9 153.8 70.5 0.9 29.6 -4.0 17.6 33 34 A a < + 0 0 3 -3,-3.3 -1,-0.2 1,-0.1 -28,-0.2 -0.417 20.1 170.4 -75.9 135.6 30.0 -0.8 15.7 34 35 A E S S+ 0 0 52 -30,-2.1 24,-2.3 1,-0.3 25,-2.3 0.755 70.4 32.7-106.9 -41.1 28.0 -0.2 12.4 35 36 A V E -ab 5 59A 26 -31,-2.1 -29,-2.4 23,-0.2 2,-0.8 -0.990 68.3-152.9-123.0 123.4 28.7 3.5 11.6 36 37 A V E -ab 6 60A 0 23,-2.9 25,-2.6 -2,-0.4 26,-0.4 -0.868 4.7-168.1-101.0 106.8 32.0 5.2 12.4 37 38 A L S S+ 0 0 45 -31,-2.1 -29,-0.2 -2,-0.8 -30,-0.2 0.828 79.3 25.1 -56.2 -37.4 31.5 9.0 13.0 38 39 A G S S- 0 0 19 -31,-0.8 24,-2.6 -32,-0.3 23,-0.5 0.229 113.1 -44.8-101.9-139.5 35.3 9.5 12.9 39 40 A N - 0 0 4 -30,-0.4 -30,-1.6 23,-0.2 2,-0.6 -0.672 40.4-133.9 -95.0 156.9 38.0 7.5 11.3 40 41 A L E -f 64 0B 0 23,-2.6 25,-3.2 -2,-0.3 2,-0.5 -0.954 27.3-178.8-103.5 120.4 38.6 3.7 11.3 41 42 A E E -f 65 0B 5 -2,-0.6 2,-0.6 23,-0.2 25,-0.2 -0.969 9.6-174.2-124.5 116.1 42.2 2.9 12.0 42 43 A I E +f 66 0B 0 23,-3.6 25,-2.1 -2,-0.5 2,-0.4 -0.936 25.6 161.4-114.0 116.5 43.3 -0.7 12.1 43 44 A T E -f 67 0B 3 -2,-0.6 25,-0.2 23,-0.2 26,-0.1 -0.973 44.8 -0.6-148.2 136.9 46.9 -0.8 13.3 44 45 A Y S S+ 0 0 46 23,-1.4 2,-0.5 -2,-0.4 25,-0.2 0.659 71.4 160.3 61.4 20.3 49.6 -3.0 14.7 45 46 A V - 0 0 2 22,-0.3 26,-2.5 -23,-0.1 25,-2.5 -0.641 25.7-148.6 -81.2 124.2 47.4 -6.1 14.9 46 47 A Q > - 0 0 39 -2,-0.5 3,-1.2 24,-0.2 26,-0.2 -0.249 29.6 -62.9 -90.9 172.1 49.4 -9.3 15.1 47 48 A R T 3 S+ 0 0 75 1,-0.2 -1,-0.2 24,-0.2 24,-0.1 -0.253 115.2 13.0 -51.1 132.9 49.0 -13.0 13.9 48 49 A N T 3 S+ 0 0 153 1,-0.3 2,-0.6 -3,-0.1 -1,-0.2 0.710 81.8 135.0 74.0 25.0 46.1 -14.8 15.4 49 50 A Y < - 0 0 65 -3,-1.2 2,-0.6 2,-0.0 -1,-0.3 -0.944 61.0-120.7 -99.0 122.3 44.2 -12.0 16.9 50 51 A D + 0 0 109 -2,-0.6 3,-0.3 1,-0.1 -3,-0.0 -0.514 36.2 172.8 -64.7 111.8 40.5 -12.4 16.1 51 52 A L > + 0 0 5 -2,-0.6 3,-1.2 1,-0.2 -1,-0.1 -0.024 40.2 117.7-105.0 26.6 39.4 -9.3 14.2 52 53 A S G > + 0 0 46 1,-0.3 3,-2.2 2,-0.2 -1,-0.2 0.721 52.9 78.1 -74.7 -21.5 36.0 -10.6 13.3 53 54 A F G > S+ 0 0 18 1,-0.3 3,-1.9 -3,-0.3 -1,-0.3 0.790 80.5 75.8 -53.6 -25.6 34.0 -7.9 15.2 54 55 A L G X S+ 0 0 0 -3,-1.2 3,-1.2 1,-0.3 24,-0.4 0.557 70.7 83.7 -62.3 -11.0 34.9 -5.7 12.2 55 56 A K G < S+ 0 0 90 -3,-2.2 -1,-0.3 1,-0.2 -2,-0.1 0.689 82.4 62.9 -66.4 -16.8 32.2 -7.6 10.2 56 57 A T G < S+ 0 0 45 -3,-1.9 2,-0.7 -4,-0.2 -1,-0.2 0.677 74.8 110.0 -80.6 -17.3 29.7 -5.1 11.7 57 58 A I < + 0 0 0 -3,-1.2 21,-0.3 1,-0.2 -23,-0.2 -0.461 30.1 160.5 -75.2 109.5 31.1 -2.0 10.2 58 59 A Q + 0 0 59 -24,-2.3 22,-3.0 -2,-0.7 23,-1.1 0.824 61.0 21.0 -88.1 -39.3 28.8 -0.6 7.5 59 60 A E E -bc 35 81A 28 -25,-2.3 -23,-2.9 20,-0.2 2,-0.4 -0.992 50.3-163.3-142.6 140.9 30.0 3.0 7.1 60 61 A V E -bc 36 82A 0 21,-2.6 23,-3.1 -2,-0.4 24,-0.4 -0.988 0.8-171.7-122.9 129.1 32.9 5.3 7.8 61 62 A A S S+ 0 0 14 -25,-2.6 24,-2.3 -23,-0.5 23,-0.9 0.941 77.8 31.6 -79.9 -49.9 32.6 9.0 7.8 62 63 A G S S- 0 0 4 -24,-2.6 22,-1.5 -26,-0.4 2,-0.2 0.574 110.4 -53.4 -81.5-130.9 36.3 9.9 8.0 63 64 A Y - 0 0 5 21,-0.2 -23,-2.6 24,-0.1 2,-0.5 -0.704 39.9-129.0-106.0 169.1 39.1 7.9 6.5 64 65 A V E -fg 40 94B 0 29,-2.1 31,-2.5 -2,-0.2 2,-0.5 -0.974 23.1-173.3-114.5 120.8 40.1 4.3 6.8 65 66 A L E +fg 41 95B 0 -25,-3.2 -23,-3.6 -2,-0.5 2,-0.4 -0.968 8.1 177.3-114.4 132.4 43.7 3.5 7.7 66 67 A I E +fg 42 96B 0 29,-3.0 31,-2.5 -2,-0.5 2,-0.4 -0.925 25.5 147.6-131.1 105.4 45.0 -0.0 7.7 67 68 A A E +fg 43 97B 1 -25,-2.1 -23,-1.4 -2,-0.4 -22,-0.3 -0.992 48.5 8.4-147.7 147.6 48.7 -0.1 8.6 68 69 A L S S+ 0 0 41 29,-1.9 2,-0.3 -2,-0.4 31,-0.2 0.676 79.9 145.1 61.9 22.7 51.5 -2.1 10.2 69 70 A N - 0 0 0 28,-0.3 38,-0.5 -25,-0.2 -1,-0.2 -0.719 32.7-179.3 -85.9 138.0 49.2 -5.1 10.7 70 71 A T + 0 0 2 -25,-2.5 -24,-0.2 -2,-0.3 36,-0.1 0.444 46.3 123.3-107.7 -6.1 50.6 -8.7 10.4 71 72 A V - 0 0 6 -26,-2.5 37,-0.3 -24,-0.1 -24,-0.2 -0.194 64.5-133.2 -52.4 143.5 47.2 -10.2 11.1 72 73 A E S S+ 0 0 73 35,-0.2 37,-3.2 -26,-0.2 36,-1.8 0.929 81.6 28.6 -70.2 -49.7 46.2 -12.5 8.2 73 74 A R B -j 109 0C 76 35,-0.2 37,-0.2 34,-0.1 -22,-0.2 -0.888 51.3-169.3-115.3 141.9 42.6 -11.4 7.6 74 75 A I - 0 0 0 35,-3.5 2,-2.3 -2,-0.4 -22,-0.1 -0.856 19.6-158.9-123.4 91.8 41.0 -8.0 8.1 75 76 A P + 0 0 6 0, 0.0 2,-1.9 0, 0.0 3,-0.2 -0.348 32.2 153.8 -79.9 63.5 37.4 -9.0 7.6 76 77 A L > + 0 0 0 -2,-2.3 3,-0.6 1,-0.2 38,-0.4 -0.435 19.6 152.4 -79.7 60.4 35.8 -5.6 6.7 77 78 A E T 3 + 0 0 22 -2,-1.9 -1,-0.2 1,-0.2 -22,-0.1 0.566 64.7 36.1 -76.8 -15.2 33.2 -7.5 4.8 78 79 A N T 3 S+ 0 0 63 -24,-0.4 2,-0.8 -21,-0.3 -1,-0.2 0.351 73.1 129.8-124.0 6.5 30.3 -5.1 5.1 79 80 A L < + 0 0 0 -3,-0.6 -21,-0.2 1,-0.2 -20,-0.2 -0.470 26.8 170.6 -56.6 102.1 32.0 -1.7 4.8 80 81 A Q + 0 0 37 -22,-3.0 36,-2.3 -2,-0.8 37,-1.8 0.846 55.4 20.1 -86.0 -33.5 29.8 -0.1 2.1 81 82 A I E -cd 59 117A 0 -23,-1.1 -21,-2.6 34,-0.2 2,-0.5 -0.999 43.7-167.0-148.5 133.4 31.1 3.5 2.1 82 83 A I E -cd 60 118A 0 35,-2.2 37,-2.6 -2,-0.3 38,-0.5 -0.986 11.9-170.5-114.7 113.7 34.0 5.7 3.1 83 84 A R - 0 0 16 -23,-3.1 37,-0.6 -2,-0.5 -22,-0.2 0.918 22.4-143.5 -73.3 -38.1 32.8 9.4 3.0 84 85 A G + 0 0 5 -22,-1.5 -22,-0.3 -23,-0.9 -21,-0.2 0.958 40.0 158.4 70.9 49.9 36.3 10.9 3.5 85 86 A N S S+ 0 0 114 -24,-2.3 2,-0.3 -47,-0.1 -23,-0.2 0.655 78.4 27.2 -76.1 -16.1 35.2 13.8 5.6 86 87 A M S S- 0 0 97 -25,-0.3 2,-0.3 34,-0.1 -1,-0.1 -0.945 80.5-138.2-137.0 161.8 38.8 13.6 6.6 87 88 A Y - 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