==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=6-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSFERASE 14-JUL-07 2Z5L . COMPND 2 MOLECULE: TYLACTONE SYNTHASE STARTER MODULE AND MODULES 1 . SOURCE 2 ORGANISM_SCIENTIFIC: STREPTOMYCES FRADIAE; . AUTHOR A.T.KEATINGE-CLAY,R.M.STROUD . 453 3 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 17801.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 337 74.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 63 13.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 18 4.0 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 42 9.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 47 10.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 148 32.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 8 1.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 1 0 0 2 1 2 3 0 1 0 1 1 1 0 0 1 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 2 1 2 3 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 1 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A S > 0 0 75 0, 0.0 3,-1.5 0, 0.0 4,-0.2 0.000 360.0 360.0 360.0 142.4 -16.2 14.4 4.2 2 2 A P G > + 0 0 121 0, 0.0 3,-0.6 0, 0.0 403,-0.0 0.704 360.0 60.5 -68.9 -18.2 -15.2 17.8 5.6 3 3 A T G > S+ 0 0 8 1,-0.2 3,-1.6 2,-0.1 4,-0.2 0.405 76.0 90.7 -89.4 1.6 -12.5 16.1 7.7 4 4 A D G X S+ 0 0 27 -3,-1.5 3,-0.8 1,-0.3 -1,-0.2 0.678 76.4 67.2 -70.3 -14.3 -10.7 14.7 4.7 5 5 A A G < S+ 0 0 47 -3,-0.6 -1,-0.3 1,-0.2 -2,-0.1 0.411 96.0 56.9 -83.6 3.5 -8.6 17.9 4.7 6 6 A W G < S+ 0 0 41 -3,-1.6 418,-2.7 419,-0.1 2,-0.6 0.390 81.9 107.4-110.3 -2.3 -7.1 16.7 8.0 7 7 A R E < +A 423 0A 3 -3,-0.8 187,-2.7 416,-0.2 2,-0.3 -0.697 40.0 159.2 -87.8 120.7 -5.8 13.4 6.7 8 8 A Y E -AB 422 193A 2 414,-3.2 414,-3.6 -2,-0.6 2,-0.3 -0.874 13.4-172.4-132.4 165.6 -2.1 13.0 6.2 9 9 A R E - B 0 192A 74 183,-2.1 183,-2.3 -2,-0.3 2,-0.6 -0.945 28.1-101.0-151.7 170.9 0.4 10.1 6.0 10 10 A V E + B 0 191A 49 -2,-0.3 2,-0.2 181,-0.2 181,-0.2 -0.886 40.7 169.7-106.0 122.0 4.1 9.3 5.8 11 11 A T E - B 0 190A 51 179,-2.6 179,-2.2 -2,-0.6 2,-0.5 -0.718 31.2-118.6-120.2 172.8 5.6 8.5 2.5 12 12 A W E - B 0 189A 47 -2,-0.2 2,-0.8 177,-0.2 177,-0.2 -0.914 17.1-161.1-122.3 108.1 9.2 8.0 1.3 13 13 A K E - B 0 188A 115 175,-2.1 175,-2.6 -2,-0.5 2,-0.5 -0.765 24.2-128.6 -89.8 111.4 10.7 10.4 -1.3 14 14 A A E B 0 187A 65 -2,-0.8 173,-0.3 173,-0.2 -1,-0.0 -0.433 360.0 360.0 -61.0 108.9 13.7 8.8 -3.0 15 15 A L 0 0 88 171,-1.5 -1,-0.2 -2,-0.5 172,-0.2 0.788 360.0 360.0 -72.8 360.0 16.4 11.5 -2.7 16 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 17 27 A G 0 0 67 0, 0.0 2,-0.7 0, 0.0 28,-0.7 0.000 360.0 360.0 360.0-165.3 35.0 16.1 10.3 18 28 A R E -c 76 0A 71 57,-0.6 59,-1.8 26,-0.3 2,-0.3 -0.630 360.0-162.0 -77.6 112.9 36.1 14.0 13.3 19 29 A C E -c 77 0A 10 -2,-0.7 28,-1.3 26,-0.4 2,-0.5 -0.661 13.2-154.1 -96.7 152.8 33.6 11.4 13.9 20 30 A L E -c 78 0A 4 57,-2.1 59,-2.6 -2,-0.3 2,-0.7 -0.966 10.1-152.9-125.9 109.2 33.0 9.4 17.1 21 31 A L E -c 79 0A 0 -2,-0.5 28,-3.5 26,-0.5 2,-0.5 -0.782 11.6-165.0 -86.7 115.3 31.4 6.0 16.5 22 32 A V E +cd 80 49A 0 57,-2.6 59,-3.6 -2,-0.7 60,-0.4 -0.883 19.5 160.0-101.4 125.5 29.5 5.0 19.7 23 33 A A E - d 0 50A 2 26,-2.4 28,-1.8 -2,-0.5 3,-0.2 -0.987 41.3 -94.7-147.1 155.9 28.5 1.3 19.9 24 34 A P S > S- 0 0 7 0, 0.0 3,-1.7 0, 0.0 4,-0.2 -0.222 72.6 -60.0 -64.1 158.0 27.4 -1.4 22.4 25 35 A P T 3 S- 0 0 57 0, 0.0 25,-0.0 0, 0.0 28,-0.0 -0.146 116.9 -25.2 -44.6 107.3 30.1 -3.7 23.8 26 36 A T T 3 S+ 0 0 125 -3,-0.2 3,-0.2 1,-0.1 24,-0.0 0.919 79.9 170.3 47.7 54.9 31.6 -5.5 20.7 27 37 A T S < S- 0 0 47 -3,-1.7 2,-0.1 1,-0.2 -1,-0.1 0.885 70.4 -31.7 -60.6 -39.5 28.4 -5.0 18.7 28 38 A D > - 0 0 66 -4,-0.2 4,-1.8 1,-0.1 5,-0.3 -0.482 45.6-148.5 175.1 108.5 30.2 -6.1 15.5 29 39 A G H > S+ 0 0 42 -3,-0.2 4,-2.0 1,-0.2 5,-0.2 0.857 100.2 55.1 -50.7 -39.5 33.8 -5.8 14.5 30 40 A E H > S+ 0 0 142 2,-0.2 4,-3.5 1,-0.2 5,-0.2 0.977 105.2 47.7 -58.6 -63.4 32.8 -5.6 10.9 31 41 A L H > S+ 0 0 14 1,-0.2 4,-3.4 2,-0.2 5,-0.3 0.915 114.4 46.7 -45.7 -56.5 30.3 -2.7 11.1 32 42 A L H X S+ 0 0 17 -4,-1.8 4,-2.1 1,-0.2 -1,-0.2 0.894 116.4 45.2 -55.7 -42.4 32.7 -0.5 13.1 33 43 A D H X S+ 0 0 82 -4,-2.0 4,-1.4 -5,-0.3 -1,-0.2 0.852 114.2 50.4 -69.5 -35.8 35.5 -1.4 10.7 34 44 A G H X S+ 0 0 21 -4,-3.5 4,-1.9 -5,-0.2 -2,-0.2 0.934 112.3 44.7 -68.2 -47.2 33.2 -0.8 7.7 35 45 A L H X S+ 0 0 4 -4,-3.4 4,-3.0 -5,-0.2 5,-0.3 0.897 108.0 57.7 -64.3 -43.1 32.0 2.6 8.9 36 46 A T H X S+ 0 0 22 -4,-2.1 4,-2.6 -5,-0.3 5,-0.2 0.922 109.3 46.4 -52.8 -47.0 35.4 3.9 9.8 37 47 A T H X S+ 0 0 77 -4,-1.4 4,-2.4 2,-0.2 -2,-0.2 0.961 113.9 45.5 -61.0 -56.2 36.6 3.2 6.3 38 48 A V H < S+ 0 0 12 -4,-1.9 -2,-0.2 1,-0.2 -1,-0.2 0.908 116.8 45.9 -55.6 -46.0 33.7 4.8 4.5 39 49 A L H >< S+ 0 0 6 -4,-3.0 3,-1.5 1,-0.2 5,-0.5 0.918 111.3 50.6 -65.1 -46.3 33.8 7.9 6.8 40 50 A S H >X S+ 0 0 60 -4,-2.6 3,-2.4 -5,-0.3 4,-0.5 0.885 99.3 64.8 -60.5 -40.1 37.5 8.4 6.6 41 51 A E T 3< S+ 0 0 145 -4,-2.4 -1,-0.3 1,-0.3 -2,-0.2 0.338 101.8 55.1 -66.8 13.0 37.4 8.3 2.8 42 52 A R T <4 S- 0 0 99 -3,-1.5 -1,-0.3 2,-0.1 -2,-0.2 0.133 132.4 -86.4-130.1 17.1 35.4 11.5 3.3 43 53 A G T <4 S+ 0 0 63 -3,-2.4 2,-0.4 1,-0.3 -3,-0.2 0.881 82.7 142.8 78.8 40.8 37.8 13.5 5.3 44 54 A A < - 0 0 15 -4,-0.5 2,-0.8 -5,-0.5 -1,-0.3 -0.935 46.5-147.0-118.7 138.8 36.7 12.1 8.7 45 55 A S - 0 0 82 -28,-0.7 -26,-0.4 -2,-0.4 2,-0.2 -0.873 27.9-154.5-102.7 100.3 38.9 11.3 11.7 46 56 A V + 0 0 33 -2,-0.8 2,-0.3 -28,-0.2 -26,-0.2 -0.534 22.0 171.9 -83.5 141.3 37.2 8.3 13.3 47 57 A A - 0 0 48 -28,-1.3 -26,-0.5 -2,-0.2 2,-0.1 -0.861 22.7-143.0-148.0 106.9 37.5 7.4 17.0 48 58 A R - 0 0 123 -2,-0.3 2,-0.3 -28,-0.2 -26,-0.2 -0.377 13.9-167.9 -76.7 148.0 35.3 4.6 18.3 49 59 A L E -d 22 0A 31 -28,-3.5 -26,-2.4 -2,-0.1 2,-0.6 -0.977 13.7-137.6-132.7 148.7 33.7 4.5 21.8 50 60 A E E +d 23 0A 104 -2,-0.3 -28,-0.1 -28,-0.2 -2,-0.0 -0.920 22.9 171.1-113.2 120.4 31.9 1.7 23.7 51 61 A V - 0 0 0 -28,-1.8 3,-0.1 -2,-0.6 -2,-0.0 -0.955 26.8-134.6-128.7 114.2 28.7 2.4 25.7 52 62 A P > - 0 0 54 0, 0.0 3,-1.8 0, 0.0 8,-0.0 -0.306 26.1-105.7 -67.6 145.4 26.8 -0.6 27.1 53 63 A I T 3 S+ 0 0 54 1,-0.3 37,-0.1 -28,-0.0 3,-0.1 -0.398 110.7 39.1 -63.7 146.2 23.1 -0.8 26.8 54 64 A G T 3 S+ 0 0 40 35,-0.6 -1,-0.3 1,-0.3 36,-0.1 0.141 83.5 139.4 95.1 -22.5 21.5 -0.0 30.2 55 65 A A < - 0 0 5 -3,-1.8 -1,-0.3 1,-0.1 2,-0.2 -0.321 46.6-135.5 -60.2 135.6 24.1 2.7 30.8 56 66 A R >> - 0 0 130 -3,-0.1 4,-2.9 1,-0.1 3,-0.7 -0.522 25.0-100.1 -90.9 161.5 22.5 5.9 32.4 57 67 A R H 3> S+ 0 0 68 1,-0.3 4,-3.4 2,-0.2 5,-0.2 0.864 121.9 53.0 -47.5 -48.5 23.2 9.5 31.4 58 68 A A H 3> S+ 0 0 68 1,-0.2 4,-1.5 2,-0.2 -1,-0.3 0.891 113.7 44.3 -57.0 -40.7 25.7 10.1 34.2 59 69 A E H <> S+ 0 0 91 -3,-0.7 4,-1.5 2,-0.2 -2,-0.2 0.940 114.2 48.4 -70.2 -46.2 27.7 7.0 33.1 60 70 A V H X S+ 0 0 0 -4,-2.9 4,-2.2 1,-0.2 5,-0.3 0.889 106.8 56.6 -62.3 -38.7 27.5 7.9 29.4 61 71 A A H X S+ 0 0 19 -4,-3.4 4,-3.2 -5,-0.3 -1,-0.2 0.943 106.2 52.0 -57.2 -45.4 28.6 11.5 30.1 62 72 A E H < S+ 0 0 156 -4,-1.5 -1,-0.2 1,-0.2 -2,-0.2 0.819 110.2 47.7 -59.5 -34.3 31.7 10.0 31.8 63 73 A L H < S+ 0 0 65 -4,-1.5 4,-0.4 -3,-0.2 -1,-0.2 0.834 119.8 37.5 -77.1 -33.0 32.5 7.8 28.8 64 74 A L H >X S+ 0 0 0 -4,-2.2 4,-2.2 -5,-0.2 3,-1.0 0.825 95.3 84.9 -85.3 -35.9 32.1 10.7 26.3 65 75 A K H 3X S+ 0 0 104 -4,-3.2 4,-1.8 -5,-0.3 5,-0.2 0.808 92.2 44.6 -33.7 -56.9 33.6 13.5 28.4 66 76 A P H 34 S+ 0 0 82 0, 0.0 -1,-0.3 0, 0.0 4,-0.2 0.835 117.1 43.5 -65.6 -33.8 37.2 12.7 27.4 67 77 A S H <4 S+ 0 0 36 -3,-1.0 -2,-0.2 -4,-0.4 -3,-0.1 0.746 113.4 51.1 -82.5 -25.9 36.6 12.3 23.6 68 78 A M H >< S+ 0 0 0 -4,-2.2 3,-1.1 1,-0.2 4,-0.3 0.875 110.4 46.3 -78.6 -42.2 34.2 15.3 23.3 69 79 A E T 3< S+ 0 0 103 -4,-1.8 3,-0.3 -5,-0.3 -1,-0.2 0.552 96.3 77.8 -77.7 -6.6 36.5 17.8 24.9 70 80 A S T 3 S+ 0 0 73 1,-0.2 -1,-0.2 -4,-0.2 -2,-0.2 0.573 93.6 50.4 -77.2 -9.9 39.3 16.5 22.8 71 81 A A S X S- 0 0 8 -3,-1.1 3,-2.2 1,-0.2 -1,-0.2 0.593 83.2-177.5-101.8 -15.3 37.9 18.5 19.9 72 82 A G T 3 S- 0 0 38 -4,-0.3 -1,-0.2 -3,-0.3 4,-0.1 -0.321 74.9 -3.9 55.4-122.5 37.6 21.8 21.7 73 83 A E T 3 S+ 0 0 157 -2,-0.1 -1,-0.3 2,-0.1 -2,-0.1 0.779 116.3 99.0 -71.6 -27.4 36.1 24.3 19.3 74 84 A E S < S- 0 0 124 -3,-2.2 2,-0.3 1,-0.1 -3,-0.1 -0.167 84.4-103.8 -58.0 154.6 36.1 21.8 16.5 75 85 A N - 0 0 58 34,-0.1 2,-0.6 2,-0.0 -57,-0.6 -0.660 26.1-153.6 -85.5 137.0 32.8 19.9 15.8 76 86 A T E -ce 18 109A 3 32,-1.5 34,-1.7 -2,-0.3 2,-0.9 -0.944 5.1-154.0-112.6 112.8 32.5 16.3 17.0 77 87 A T E -ce 19 110A 22 -59,-1.8 -57,-2.1 -2,-0.6 2,-0.6 -0.786 11.9-153.4 -89.5 107.3 30.0 14.4 14.9 78 88 A V E -ce 20 111A 0 32,-2.2 34,-3.2 -2,-0.9 2,-0.7 -0.724 8.2-167.2 -85.7 117.3 28.7 11.6 17.1 79 89 A V E -ce 21 112A 0 -59,-2.6 -57,-2.6 -2,-0.6 2,-0.5 -0.907 11.2-157.5-106.4 105.9 27.5 8.5 15.2 80 90 A S E +ce 22 113A 3 32,-2.9 34,-2.4 -2,-0.7 3,-0.2 -0.729 24.0 176.7 -91.7 127.8 25.5 6.2 17.5 81 91 A L > + 0 0 0 -59,-3.6 3,-2.0 -2,-0.5 4,-0.2 0.284 58.2 103.3-105.2 7.0 25.1 2.5 16.8 82 92 A L G > S+ 0 0 0 -60,-0.4 3,-1.4 1,-0.3 -1,-0.1 0.839 72.1 64.3 -59.4 -31.0 23.2 2.0 20.0 83 93 A G G 3 S+ 0 0 7 31,-0.4 33,-0.5 1,-0.3 -1,-0.3 0.547 81.4 77.7 -71.7 -6.7 19.9 1.8 18.0 84 94 A L G < S+ 0 0 18 -3,-2.0 -1,-0.3 31,-0.2 -2,-0.2 0.587 76.1 88.8 -78.1 -8.1 21.0 -1.3 16.2 85 95 A V S < S- 0 0 34 -3,-1.4 2,-2.0 -4,-0.2 5,-0.2 -0.826 82.3-134.5 -93.2 114.6 20.1 -3.3 19.3 86 96 A P + 0 0 90 0, 0.0 2,-0.3 0, 0.0 -2,-0.1 -0.437 66.8 98.8 -68.4 77.9 16.4 -4.3 19.1 87 97 A S S > S- 0 0 37 -2,-2.0 4,-1.0 -4,-0.1 3,-0.5 -0.983 76.9-125.1-161.4 152.6 15.4 -3.4 22.7 88 98 A T H > S+ 0 0 29 -2,-0.3 4,-2.7 1,-0.2 5,-0.2 0.815 112.1 65.2 -68.4 -29.7 13.8 -0.7 24.6 89 99 A D H > S+ 0 0 75 1,-0.2 4,-3.0 2,-0.2 -35,-0.6 0.866 97.8 55.3 -58.7 -35.4 16.9 -0.6 26.8 90 100 A A H > S+ 0 0 2 -3,-0.5 4,-1.9 2,-0.2 -1,-0.2 0.895 107.5 48.2 -63.5 -42.8 18.6 0.6 23.6 91 101 A V H X S+ 0 0 1 -4,-1.0 4,-2.5 2,-0.2 -2,-0.2 0.908 112.2 49.5 -63.2 -43.2 16.1 3.4 23.3 92 102 A R H X S+ 0 0 71 -4,-2.7 4,-2.2 1,-0.2 -2,-0.2 0.946 114.0 44.5 -61.4 -47.2 16.6 4.3 26.9 93 103 A T H X S+ 0 0 1 -4,-3.0 4,-1.6 1,-0.2 -1,-0.2 0.777 111.2 55.0 -68.1 -28.2 20.4 4.3 26.5 94 104 A S H X S+ 0 0 10 -4,-1.9 4,-1.9 2,-0.2 -1,-0.2 0.903 108.3 47.3 -70.9 -43.2 20.1 6.3 23.3 95 105 A I H X S+ 0 0 8 -4,-2.5 4,-2.6 1,-0.2 -2,-0.2 0.931 110.7 54.0 -62.0 -42.5 18.1 9.0 25.0 96 106 A A H X S+ 0 0 5 -4,-2.2 4,-2.0 1,-0.2 -1,-0.2 0.854 104.8 54.7 -58.4 -38.6 20.8 8.9 27.7 97 107 A L H X S+ 0 0 2 -4,-1.6 4,-1.9 2,-0.2 -1,-0.2 0.915 109.7 45.6 -62.9 -45.7 23.5 9.4 25.1 98 108 A L H X S+ 0 0 1 -4,-1.9 4,-2.0 1,-0.2 -2,-0.2 0.945 112.4 51.2 -62.7 -48.1 21.8 12.6 23.8 99 109 A Q H X S+ 0 0 10 -4,-2.6 4,-2.0 1,-0.2 -1,-0.2 0.844 110.0 50.7 -56.6 -37.6 21.3 13.9 27.3 100 110 A A H X S+ 0 0 0 -4,-2.0 4,-2.6 2,-0.2 -1,-0.2 0.877 107.0 52.3 -70.3 -39.3 24.9 13.3 28.1 101 111 A V H X>S+ 0 0 3 -4,-1.9 5,-0.7 1,-0.2 4,-0.5 0.868 111.1 48.0 -64.2 -37.8 26.1 15.2 25.0 102 112 A S H ><5S+ 0 0 40 -4,-2.0 3,-0.8 2,-0.2 -1,-0.2 0.911 111.1 52.0 -68.4 -43.0 24.0 18.1 26.0 103 113 A D H 3<5S+ 0 0 72 -4,-2.0 -2,-0.2 1,-0.2 -1,-0.2 0.925 101.5 57.7 -60.4 -48.4 25.3 18.0 29.5 104 114 A I H 3<5S- 0 0 24 -4,-2.6 -1,-0.2 1,-0.1 -2,-0.2 0.717 94.6-149.1 -56.5 -19.9 29.0 18.0 28.5 105 115 A G T <<5 + 0 0 54 -3,-0.8 -3,-0.1 -4,-0.5 -1,-0.1 0.863 27.2 173.3 51.1 42.6 28.3 21.3 26.8 106 116 A V < - 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0 0 95 -4,-0.8 -3,-0.2 -5,-0.2 -2,-0.1 0.880 39.5-171.1 67.1 42.2 -9.3 0.4 6.3 418 451 A D < - 0 0 9 -5,-2.1 -47,-0.2 1,-0.1 3,-0.1 -0.163 25.1-159.2 -61.1 157.4 -6.2 2.5 6.9 419 452 A V S S- 0 0 42 1,-0.4 -46,-2.7 -47,-0.2 2,-0.4 0.794 80.3 -2.5-100.8 -56.5 -3.1 1.1 8.6 420 453 A C E S+ n 0 373A 32 -48,-0.2 -1,-0.4 -59,-0.1 2,-0.3 -0.998 72.5 159.1-140.3 134.9 -1.6 4.5 9.8 421 454 A V E - n 0 374A 4 -48,-1.8 -46,-2.5 -2,-0.4 2,-0.6 -0.984 33.5-131.4-152.8 149.4 -2.9 7.9 9.1 422 455 A T E -An 8 375A 4 -414,-3.6 -414,-3.2 -2,-0.3 2,-0.7 -0.933 18.5-170.1-106.4 118.6 -2.5 11.3 10.7 423 456 A V E +An 7 376A 0 -48,-0.8 -46,-0.9 -2,-0.6 2,-0.3 -0.896 28.6 143.7-110.3 100.9 -5.7 13.1 11.3 424 457 A V - 0 0 0 -418,-2.7 2,-0.7 -2,-0.7 -24,-0.1 -0.997 46.2-138.0-141.7 147.4 -4.9 16.7 12.3 425 458 A D + 0 0 20 -26,-0.5 -26,-3.1 -2,-0.3 2,-0.4 -0.906 37.3 171.6-105.2 112.3 -6.3 20.2 11.9 426 459 A V B -Q 398 0D 7 -2,-0.7 2,-1.6 -28,-0.2 -28,-0.2 -0.976 40.6-138.9-131.4 137.2 -3.4 22.6 11.1 427 460 A D >> - 0 0 56 -30,-3.3 3,-2.1 -2,-0.4 4,-1.3 -0.630 24.8-174.6 -87.1 79.0 -3.1 26.2 10.1 428 461 A W H 3> S+ 0 0 8 -2,-1.6 4,-1.3 1,-0.3 -1,-0.2 0.744 78.2 69.7 -46.6 -29.7 -0.2 25.6 7.7 429 462 A E H 34 S+ 0 0 103 1,-0.2 -1,-0.3 2,-0.1 -2,-0.1 0.303 114.8 27.8 -75.0 13.4 0.1 29.3 7.1 430 463 A R H <> S+ 0 0 120 -3,-2.1 4,-0.7 -34,-0.1 -2,-0.2 0.422 119.3 54.6-143.8 -20.1 1.4 29.4 10.7 431 464 A F H X S+ 0 0 1 -4,-1.3 4,-3.3 -34,-0.2 5,-0.4 0.937 102.0 52.7 -85.1 -56.5 3.0 25.9 11.2 432 465 A A H X S+ 0 0 5 -4,-1.3 4,-1.6 1,-0.2 5,-0.1 0.919 115.4 40.7 -47.6 -54.7 5.4 25.8 8.3 433 466 A P H > S+ 0 0 54 0, 0.0 4,-1.4 0, 0.0 -1,-0.2 0.912 118.8 46.9 -63.9 -41.1 7.1 29.1 9.1 434 467 A A H >X S+ 0 0 32 -4,-0.7 4,-1.3 -38,-0.2 3,-0.5 0.960 113.6 45.0 -64.1 -55.6 7.1 28.4 12.9 435 468 A T H 3X S+ 0 0 11 -4,-3.3 4,-2.2 -39,-0.3 -1,-0.2 0.812 113.5 52.7 -60.1 -30.4 8.4 24.9 12.8 436 469 A N H 3< S+ 0 0 62 -4,-1.6 -1,-0.3 -5,-0.4 -2,-0.2 0.794 100.8 60.1 -77.8 -26.6 11.0 26.0 10.3 437 470 A A H << S+ 0 0 89 -4,-1.4 -1,-0.2 -3,-0.5 -2,-0.2 0.833 112.5 39.2 -67.7 -33.3 12.2 28.8 12.6 438 471 A I H < S- 0 0 72 -4,-1.3 -2,-0.2 1,-0.3 -1,-0.2 0.925 139.7 -1.4 -79.9 -49.9 13.0 26.2 15.3 439 472 A R S < S- 0 0 32 -4,-2.2 -1,-0.3 -5,-0.2 2,-0.1 -0.942 70.5-139.2-148.7 118.5 14.4 23.6 12.9 440 473 A P + 0 0 82 0, 0.0 2,-0.3 0, 0.0 -4,-0.1 -0.493 40.2 140.9 -76.1 148.1 14.7 23.8 9.1 441 474 A G - 0 0 29 -2,-0.1 3,-0.2 -265,-0.1 -265,-0.1 -0.995 59.8-114.0-174.8 173.0 13.8 20.6 7.1 442 475 A R S > S+ 0 0 89 -267,-0.6 3,-1.1 -2,-0.3 4,-0.5 0.425 82.7 101.0 -99.3 -2.9 12.3 18.8 4.2 443 476 A L T 3 S+ 0 0 15 1,-0.3 -252,-2.4 2,-0.1 3,-0.5 0.889 90.8 29.8 -50.0 -53.4 9.6 16.9 6.2 444 477 A F T > S+ 0 0 24 1,-0.2 3,-1.7 -254,-0.2 7,-0.3 0.296 89.0 100.5 -94.9 9.3 6.7 19.2 5.4 445 478 A D T < S+ 0 0 35 -3,-1.1 6,-0.3 1,-0.3 -1,-0.2 0.849 73.4 67.1 -62.5 -30.1 7.8 20.2 1.9 446 479 A T T 3 S+ 0 0 51 -4,-0.5 -253,-0.4 -3,-0.5 -1,-0.3 0.331 85.0 88.8 -72.2 9.4 5.4 17.7 0.5 447 480 A V X> - 0 0 0 -3,-1.7 4,-2.4 1,-0.2 3,-0.7 -0.945 69.5-150.7-113.4 116.7 2.5 19.7 1.8 448 481 A P H 3> S+ 0 0 73 0, 0.0 4,-1.0 0, 0.0 -1,-0.2 0.914 96.9 46.2 -45.2 -61.7 1.2 22.5 -0.5 449 482 A E H 3> S+ 0 0 61 1,-0.2 4,-1.3 2,-0.2 5,-0.1 0.741 113.3 53.6 -58.0 -25.2 -0.0 24.9 2.2 450 483 A A H <> S+ 0 0 0 -3,-0.7 4,-1.7 -6,-0.2 3,-0.3 0.962 103.7 51.1 -75.1 -54.5 3.3 24.4 3.9 451 484 A R H < S+ 0 0 129 -4,-2.4 -2,-0.2 -7,-0.3 -1,-0.2 0.657 107.9 60.8 -58.2 -14.4 5.6 25.2 1.0 452 485 A E H < S+ 0 0 119 -4,-1.0 -1,-0.2 -5,-0.3 -2,-0.2 0.949 103.7 41.6 -78.5 -55.3 3.5 28.4 0.7 453 486 A A H < S+ 0 0 20 -4,-1.3 -2,-0.2 -3,-0.3 -1,-0.1 0.788 99.1 98.9 -64.1 -25.9 4.1 30.1 4.0 454 487 A L < 0 0 31 -4,-1.7 -22,-0.0 1,-0.1 -25,-0.0 -0.351 360.0 360.0 -65.2 140.1 7.7 29.0 3.7 455 488 A T 0 0 187 -2,-0.1 -1,-0.1 -22,-0.0 -2,-0.0 0.744 360.0 360.0-114.4 360.0 10.1 31.7 2.4