==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER IMMUNE SYSTEM 22-JUL-07 2Z62 . COMPND 2 MOLECULE: TOLL-LIKE RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTO . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS, EPTATRETUS BURGERI; . AUTHOR J.-O.LEE,H.M.KIM,B.S.PARK . 276 1 3 3 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13091.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 186 67.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 51 18.5 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 7 2.5 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 32 11.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 46 16.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 13 4.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 2 3 8 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 27 A E 0 0 151 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 132.6 41.0 -2.2 31.6 2 28 A P + 0 0 65 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.881 360.0 79.3 -81.1 -36.1 40.8 -2.2 27.8 3 29 A a S S- 0 0 9 1,-0.1 2,-0.5 11,-0.1 11,-0.2 -0.216 84.2-113.2 -70.2 158.4 37.4 -0.6 27.5 4 30 A V E -A 13 0A 76 9,-2.9 9,-2.6 1,-0.0 2,-1.0 -0.819 19.8-140.0 -93.4 128.7 36.8 3.2 27.8 5 31 A E E +A 12 0A 103 -2,-0.5 7,-0.2 7,-0.2 9,-0.0 -0.777 30.1 166.9 -89.7 98.9 34.7 4.2 30.8 6 32 A V E S+ 0 0 88 5,-2.0 -1,-0.2 -2,-1.0 6,-0.2 0.944 78.1 9.0 -78.3 -51.6 32.5 7.0 29.5 7 33 A V E >> S-A 11 0A 63 4,-1.6 3,-2.4 0, 0.0 4,-2.1 -0.984 93.3-112.6-128.9 121.8 30.2 7.1 32.5 8 34 A P T 34 S+ 0 0 77 0, 0.0 4,-0.1 0, 0.0 -3,-0.0 -0.234 99.6 0.8 -55.9 136.2 31.2 5.1 35.6 9 35 A N T 34 S+ 0 0 90 1,-0.1 3,-0.1 2,-0.1 -4,-0.0 0.316 136.4 53.1 71.1 -5.2 28.9 2.1 36.1 10 36 A I T <4 S+ 0 0 48 -3,-2.4 22,-2.7 1,-0.3 21,-2.4 0.769 98.8 35.4-128.7 -51.7 26.8 3.1 33.0 11 37 A T E < +Ab 7 32A 31 -4,-2.1 -5,-2.0 20,-0.2 -4,-1.6 -0.969 54.5 175.9-128.4 119.2 28.5 3.6 29.6 12 38 A Y E -Ab 5 33A 2 20,-2.5 22,-2.0 -2,-0.5 2,-0.6 -0.975 16.7-154.9-126.5 134.8 31.4 1.6 28.3 13 39 A Q E +Ab 4 34A 56 -9,-2.6 -9,-2.9 -2,-0.4 22,-0.1 -0.932 20.3 165.4-112.8 111.3 33.1 1.8 24.9 14 40 A a > + 0 0 0 20,-3.0 3,-0.6 -2,-0.6 5,-0.2 -0.160 20.7 156.9-116.3 35.1 34.8 -1.4 23.8 15 41 A M T 3 - 0 0 77 1,-0.2 22,-0.2 2,-0.1 21,-0.1 -0.419 64.9 -6.8 -72.9 132.6 35.3 -0.6 20.1 16 42 A E T 3 S+ 0 0 144 20,-2.0 -1,-0.2 -2,-0.2 22,-0.2 0.892 83.9 132.9 55.0 53.0 38.0 -2.4 18.1 17 43 A L S < S- 0 0 61 -3,-0.6 -1,-0.1 18,-0.1 21,-0.1 0.193 75.6-109.8-115.8 15.7 39.7 -4.2 21.0 18 44 A N + 0 0 110 19,-0.5 2,-0.5 1,-0.2 20,-0.1 0.859 54.1 172.3 53.7 41.3 40.0 -7.6 19.4 19 45 A F + 0 0 30 -5,-0.2 -1,-0.2 1,-0.1 -2,-0.1 -0.700 20.2 178.2 -77.5 127.4 37.4 -9.2 21.8 20 46 A Y S S+ 0 0 131 -2,-0.5 2,-0.3 18,-0.1 -1,-0.1 0.449 73.9 35.8-101.1 -9.1 36.5 -12.7 20.7 21 47 A K S S- 0 0 173 20,-0.1 -1,-0.1 22,-0.0 3,-0.1 -0.940 100.6 -86.8-138.7 158.7 34.1 -13.0 23.7 22 48 A I - 0 0 34 -2,-0.3 -2,-0.1 25,-0.1 13,-0.0 -0.485 58.0-103.2 -64.7 131.6 31.7 -10.6 25.5 23 49 A P - 0 0 9 0, 0.0 3,-0.1 0, 0.0 27,-0.1 -0.314 30.9-170.1 -61.3 144.0 33.8 -8.8 28.2 24 50 A D S S+ 0 0 134 1,-0.1 -2,-0.0 -3,-0.1 0, 0.0 0.298 72.0 77.0-114.9 5.9 33.3 -10.1 31.8 25 51 A N S S+ 0 0 72 2,-0.1 -1,-0.1 0, 0.0 0, 0.0 0.327 72.2 99.4-101.1 3.6 35.1 -7.2 33.6 26 52 A L S S- 0 0 18 -3,-0.1 -14,-0.0 1,-0.1 0, 0.0 -0.537 82.7 -82.9 -96.3 157.3 32.5 -4.5 33.4 27 53 A P > - 0 0 32 0, 0.0 3,-1.6 0, 0.0 -1,-0.1 -0.293 27.4-132.2 -58.7 140.9 30.0 -3.3 36.0 28 54 A F T 3 S+ 0 0 138 1,-0.3 25,-0.6 23,-0.1 -2,-0.0 0.682 106.5 63.8 -61.8 -21.1 26.7 -5.2 36.4 29 55 A S T 3 S+ 0 0 36 23,-0.1 -1,-0.3 24,-0.1 22,-0.1 0.485 72.7 138.2 -83.8 -5.6 24.9 -1.8 36.3 30 56 A T < + 0 0 0 -3,-1.6 23,-0.3 20,-0.2 -20,-0.2 -0.109 24.6 174.5 -51.5 130.6 26.0 -1.1 32.7 31 57 A K + 0 0 59 -21,-2.4 24,-3.7 1,-0.3 25,-2.1 0.668 66.5 42.5-108.0 -26.6 23.3 0.5 30.6 32 58 A N E +bc 11 56A 44 -22,-2.7 -20,-2.5 23,-0.2 2,-0.4 -0.977 63.0 176.7-133.1 119.2 25.2 1.3 27.3 33 59 A L E -bc 12 57A 4 23,-2.5 25,-2.6 -2,-0.4 2,-0.7 -0.981 12.2-167.0-131.0 121.1 27.7 -1.0 25.7 34 60 A D E +bc 13 58A 39 -22,-2.0 -20,-3.0 -2,-0.4 25,-0.1 -0.929 19.5 159.3-109.8 109.2 29.5 -0.5 22.4 35 61 A L > + 0 0 0 23,-2.8 3,-0.5 -2,-0.7 5,-0.2 0.065 25.3 147.6-112.9 19.0 31.2 -3.6 21.2 36 62 A S T 3 + 0 0 4 1,-0.2 -20,-2.0 -21,-0.1 25,-0.2 -0.153 58.0 23.6 -60.6 151.9 31.5 -2.6 17.5 37 63 A F T 3 S+ 0 0 101 23,-2.4 -19,-0.5 1,-0.2 -1,-0.2 0.828 89.4 129.2 61.4 38.7 34.4 -3.8 15.3 38 64 A N < - 0 0 1 -3,-0.5 2,-2.6 22,-0.3 3,-0.4 -0.963 68.9-116.5-119.8 140.9 35.2 -6.9 17.4 39 65 A P + 0 0 9 0, 0.0 24,-0.1 0, 0.0 23,-0.1 -0.294 59.6 142.8 -71.5 62.2 35.7 -10.4 16.1 40 66 A L + 0 0 9 -2,-2.6 2,-2.9 22,-0.6 23,-0.2 0.867 21.1 171.6 -72.3 -39.3 32.7 -11.8 18.0 41 67 A R + 0 0 105 21,-2.3 24,-3.0 -3,-0.4 25,-0.9 -0.118 57.3 32.9 67.9 -45.6 31.6 -14.2 15.2 42 68 A H E -l 66 0B 111 -2,-2.9 2,-0.6 22,-0.2 25,-0.2 -0.992 62.2-152.4-146.3 136.9 28.9 -16.2 17.0 43 69 A L E -l 67 0B 3 23,-2.4 25,-2.9 -2,-0.3 28,-0.2 -0.949 19.1-166.2-111.4 112.4 26.4 -15.4 19.7 44 70 A G > - 0 0 23 -2,-0.6 3,-0.8 1,-0.2 -2,-0.0 -0.312 41.4 -63.4 -83.4 175.1 25.4 -18.3 21.9 45 71 A S T 3 S+ 0 0 57 1,-0.2 26,-0.3 2,-0.1 -1,-0.2 -0.313 121.2 11.4 -57.4 142.7 22.4 -18.4 24.3 46 72 A Y T > S+ 0 0 136 24,-2.7 3,-1.0 22,-0.1 -1,-0.2 0.874 75.1 157.3 52.4 47.1 22.7 -16.0 27.2 47 73 A S T < S+ 0 0 20 24,-1.4 3,-0.3 -3,-0.8 25,-0.2 0.777 72.9 43.9 -66.8 -26.3 25.6 -14.1 25.7 48 74 A F T > + 0 0 1 23,-0.7 3,-2.1 1,-0.2 -1,-0.2 -0.045 67.2 128.1-116.3 30.7 24.7 -11.0 27.7 49 75 A F T < S+ 0 0 131 -3,-1.0 -1,-0.2 1,-0.3 -2,-0.1 0.776 73.8 58.5 -55.5 -29.7 24.0 -12.5 31.2 50 76 A S T 3 S+ 0 0 26 -3,-0.3 -1,-0.3 1,-0.2 -20,-0.2 0.470 102.6 56.9 -79.1 -1.7 26.5 -10.0 32.7 51 77 A F X + 0 0 1 -3,-2.1 3,-2.0 1,-0.1 -1,-0.2 -0.291 54.1 148.1-129.6 51.1 24.5 -7.0 31.4 52 78 A P T 3 S+ 0 0 25 0, 0.0 25,-0.5 0, 0.0 24,-0.1 0.703 75.4 54.1 -65.1 -19.0 20.9 -7.2 32.7 53 79 A E T 3 S+ 0 0 70 -25,-0.6 -24,-0.1 -23,-0.3 22,-0.1 0.397 78.1 139.6 -92.3 1.3 20.5 -3.4 32.8 54 80 A L < + 0 0 0 -3,-2.0 23,-0.2 -6,-0.2 -22,-0.2 -0.155 20.5 167.0 -55.0 134.7 21.5 -2.9 29.2 55 81 A Q S S+ 0 0 77 -24,-3.7 24,-2.7 1,-0.3 25,-2.4 0.649 71.1 31.3-113.1 -34.0 19.5 -0.3 27.3 56 82 A V E -cd 32 80A 46 -25,-2.1 -23,-2.5 23,-0.2 2,-0.4 -0.995 63.5-179.1-132.2 127.1 21.7 0.1 24.2 57 83 A L E -cd 33 81A 0 23,-2.3 25,-2.4 -2,-0.4 2,-0.6 -0.972 8.3-163.5-130.9 118.2 23.9 -2.6 22.7 58 84 A D E +cd 34 82A 34 -25,-2.6 -23,-2.8 -2,-0.4 25,-0.1 -0.897 21.5 159.7-105.4 114.8 26.1 -2.0 19.6 59 85 A L > + 0 0 0 23,-2.7 3,-0.8 -2,-0.6 5,-0.3 -0.041 23.8 155.6-116.9 27.5 27.3 -5.1 17.8 60 86 A S T 3 - 0 0 16 1,-0.2 -23,-2.4 2,-0.1 -22,-0.3 -0.282 67.8 -1.3 -60.0 137.4 28.1 -3.4 14.5 61 87 A R T 3 S+ 0 0 98 23,-2.6 -1,-0.2 -25,-0.2 25,-0.2 0.876 83.4 140.2 51.7 47.7 30.7 -5.0 12.3 62 88 A C < - 0 0 0 -3,-0.8 -21,-2.3 22,-0.2 -22,-0.6 0.106 69.9-115.4-107.1 20.7 31.4 -7.9 14.7 63 89 A E + 0 0 90 22,-0.4 2,-0.4 1,-0.2 23,-0.1 0.681 53.6 172.4 57.7 21.6 31.7 -10.6 12.0 64 90 A I + 0 0 0 -5,-0.3 -22,-0.2 1,-0.2 -1,-0.2 -0.484 16.3 163.8 -74.4 119.8 28.6 -12.3 13.5 65 91 A Q + 0 0 87 -24,-3.0 24,-3.1 -2,-0.4 25,-2.0 0.709 63.4 33.0-101.2 -31.4 27.4 -15.2 11.4 66 92 A T E -lm 42 90B 39 -25,-0.9 -23,-2.4 23,-0.2 2,-0.4 -0.984 53.1-170.1-134.7 141.7 25.1 -17.0 13.8 67 93 A I E -lm 43 91B 1 23,-2.3 25,-2.3 -2,-0.4 -23,-0.2 -0.974 22.7-146.3-131.2 115.4 22.8 -15.9 16.7 68 94 A E > - 0 0 99 -25,-2.9 3,-1.7 -2,-0.4 -22,-0.1 -0.267 34.2 -75.0 -77.8 164.4 21.4 -18.7 18.8 69 95 A D T 3 S+ 0 0 91 1,-0.3 26,-0.3 2,-0.1 -1,-0.2 -0.360 120.3 11.2 -53.1 130.1 18.0 -19.0 20.6 70 96 A G T > S+ 0 0 8 24,-2.5 -24,-2.7 -25,-0.2 3,-1.9 0.660 76.3 148.5 71.5 19.7 18.0 -16.8 23.6 71 97 A A T < S+ 0 0 0 -3,-1.7 -24,-1.4 -26,-0.3 -23,-0.7 0.760 85.8 26.2 -51.1 -30.6 21.3 -14.9 22.8 72 98 A Y T > S+ 0 0 0 23,-0.5 3,-2.1 25,-0.3 -1,-0.3 -0.017 81.5 131.4-123.8 26.4 19.9 -11.8 24.5 73 99 A Q T < S+ 0 0 68 -3,-1.9 -2,-0.1 1,-0.3 3,-0.1 0.804 70.9 55.2 -54.6 -34.1 17.5 -13.5 27.0 74 100 A S T 3 S+ 0 0 34 -4,-0.3 2,-1.7 1,-0.2 -1,-0.3 0.649 83.8 91.5 -70.3 -16.4 18.8 -11.5 29.9 75 101 A L X + 0 0 0 -3,-2.1 3,-1.6 1,-0.2 26,-0.4 -0.323 36.8 149.8 -93.5 58.6 18.1 -8.1 28.3 76 102 A S T 3 S+ 0 0 49 -2,-1.7 -1,-0.2 1,-0.3 -23,-0.1 0.653 77.4 45.0 -62.5 -18.7 14.6 -7.3 29.5 77 103 A H T 3 S+ 0 0 87 -25,-0.5 -1,-0.3 -23,-0.2 2,-0.1 0.392 78.3 129.8-104.6 -0.2 15.4 -3.5 29.4 78 104 A L < + 0 0 0 -3,-1.6 23,-0.3 1,-0.2 -23,-0.2 -0.367 23.0 168.7 -62.3 126.4 17.2 -3.3 26.0 79 105 A S + 0 0 28 -24,-2.7 25,-2.6 1,-0.3 24,-2.5 0.711 64.9 38.9-106.2 -32.2 15.6 -0.6 23.9 80 106 A T E +de 56 104A 24 -25,-2.4 -23,-2.3 23,-0.2 2,-0.4 -0.983 59.1 179.9-128.9 122.5 18.2 -0.3 21.1 81 107 A L E -de 57 105A 0 23,-2.5 25,-2.7 -2,-0.4 2,-0.5 -0.991 9.0-164.5-121.7 126.4 19.9 -3.2 19.4 82 108 A I E +de 58 106A 27 -25,-2.4 -23,-2.7 -2,-0.4 25,-0.2 -0.948 22.8 158.6-119.1 117.7 22.4 -2.6 16.6 83 109 A L > + 0 0 2 23,-3.6 3,-0.9 -2,-0.5 -22,-0.2 0.201 23.1 155.3-119.6 10.6 23.5 -5.4 14.3 84 110 A T T 3 + 0 0 25 22,-0.4 -23,-2.6 1,-0.2 25,-0.2 -0.057 63.7 10.6 -46.5 132.4 24.7 -3.4 11.3 85 111 A G T 3 S+ 0 0 10 23,-2.5 -22,-0.4 1,-0.2 -1,-0.2 0.780 85.5 134.8 71.4 30.1 27.3 -4.9 9.0 86 112 A N < - 0 0 2 -3,-0.9 2,-2.3 22,-0.4 -1,-0.2 -0.943 59.1-129.5-106.5 135.3 27.3 -8.5 10.3 87 113 A P - 0 0 55 0, 0.0 2,-0.2 0, 0.0 23,-0.1 -0.384 37.3-173.1 -81.6 65.5 27.2 -11.3 7.8 88 114 A I + 0 0 15 -2,-2.3 -22,-0.2 1,-0.2 -23,-0.2 -0.387 22.7 157.6 -69.3 126.7 24.3 -13.1 9.5 89 115 A Q + 0 0 131 -24,-3.1 2,-0.4 1,-0.3 -23,-0.2 0.539 66.9 41.6-123.4 -19.2 23.5 -16.5 8.0 90 116 A S E +m 66 0B 65 -25,-2.0 -23,-2.3 2,-0.0 2,-0.6 -0.917 57.5 172.9-135.9 109.1 21.7 -18.2 10.8 91 117 A L E -m 67 0B 42 -2,-0.4 -23,-0.1 -25,-0.2 -25,-0.1 -0.951 30.3-134.3-113.8 108.8 19.2 -16.3 12.9 92 118 A A > - 0 0 19 -25,-2.3 3,-2.3 -2,-0.6 4,-0.3 -0.215 19.6-115.1 -61.9 152.4 17.4 -18.7 15.3 93 119 A L T 3 S+ 0 0 161 1,-0.3 3,-0.3 2,-0.1 -1,-0.1 0.812 121.1 39.7 -58.7 -31.0 13.6 -18.5 15.6 94 120 A G T > S+ 0 0 20 1,-0.2 -24,-2.5 2,-0.1 3,-1.9 0.049 77.8 121.9-104.9 23.4 14.1 -17.4 19.2 95 121 A A T < S+ 0 0 0 -3,-2.3 -23,-0.5 1,-0.3 -24,-0.2 0.834 83.0 39.3 -51.7 -36.8 17.2 -15.2 18.5 96 122 A F T > S+ 0 0 9 23,-0.4 3,-1.5 -3,-0.3 -1,-0.3 0.149 83.7 141.1-106.5 19.0 15.3 -12.2 20.0 97 123 A S T < + 0 0 54 -3,-1.9 -25,-0.3 1,-0.2 -3,-0.1 -0.294 67.2 24.4 -55.1 139.7 13.6 -14.0 22.9 98 124 A G T 3 S+ 0 0 19 1,-0.1 2,-2.2 -24,-0.1 -1,-0.2 0.273 79.1 125.4 90.9 -11.0 13.5 -12.0 26.1 99 125 A L X + 0 0 5 -3,-1.5 3,-1.2 1,-0.2 -23,-0.1 -0.355 24.8 155.7 -83.4 62.5 13.7 -8.6 24.4 100 126 A S T 3 S+ 0 0 88 -2,-2.2 -1,-0.2 1,-0.3 -24,-0.1 0.535 71.0 39.2 -68.3 -14.0 10.6 -7.3 26.1 101 127 A S T 3 S+ 0 0 45 -26,-0.4 -1,-0.3 -23,-0.3 -2,-0.1 0.339 77.6 141.1-116.0 2.9 11.5 -3.6 25.9 102 128 A L < + 0 0 0 -3,-1.2 -23,-0.2 1,-0.2 -22,-0.2 -0.256 11.1 160.2 -59.7 126.5 13.0 -3.4 22.4 103 129 A Q + 0 0 88 -24,-2.5 24,-2.7 1,-0.3 25,-2.6 0.644 64.3 38.9-114.8 -27.2 12.0 -0.2 20.5 104 130 A K E -ef 80 128A 77 -25,-2.6 -23,-2.5 23,-0.2 2,-0.5 -0.969 56.9-177.5-136.0 119.0 14.7 0.1 17.9 105 131 A L E -ef 81 129A 0 23,-2.4 25,-2.5 -2,-0.4 2,-0.7 -0.968 7.0-167.6-115.7 117.0 16.3 -2.8 15.8 106 132 A V E +ef 82 130A 20 -25,-2.7 -23,-3.6 -2,-0.5 -22,-0.4 -0.907 20.3 158.2-108.8 108.9 19.0 -1.8 13.4 107 133 A A > + 0 0 1 23,-3.0 3,-0.6 -2,-0.7 5,-0.2 -0.254 16.3 160.2-126.0 42.4 19.9 -4.6 11.0 108 134 A V T 3 S+ 0 0 18 1,-0.2 -23,-2.5 2,-0.1 -22,-0.4 -0.427 70.2 1.8 -64.3 135.3 21.5 -2.6 8.2 109 135 A E T 3 S+ 0 0 94 23,-1.6 -23,-0.3 24,-0.4 -1,-0.2 0.935 84.8 137.9 50.7 57.4 23.7 -4.7 5.9 110 136 A T S < S- 0 0 7 -3,-0.6 -22,-0.1 -25,-0.2 -1,-0.1 0.024 78.6-101.9-119.3 23.2 23.0 -8.0 7.6 111 137 A N + 0 0 82 22,-0.3 2,-0.4 1,-0.2 23,-0.1 0.793 62.5 170.0 65.1 29.4 22.7 -10.1 4.5 112 138 A L + 0 0 12 -5,-0.2 23,-2.9 1,-0.1 -1,-0.2 -0.634 16.3 171.7 -81.4 124.5 18.8 -10.1 4.9 113 139 A A + 0 0 60 -2,-0.4 24,-0.8 1,-0.3 2,-0.3 0.581 63.9 14.4-107.8 -16.7 17.0 -11.5 1.9 114 140 A S - 0 0 33 22,-0.2 -1,-0.3 23,-0.1 4,-0.2 -0.975 49.3-145.0-160.2 145.2 13.4 -11.6 3.2 115 141 A L S > S+ 0 0 7 -2,-0.3 3,-0.6 23,-0.2 -1,-0.1 0.654 94.7 76.2 -81.1 -17.6 11.2 -10.3 6.0 116 142 A E T 3 S+ 0 0 95 1,-0.2 -1,-0.2 24,-0.1 28,-0.1 0.917 100.5 38.5 -59.9 -45.8 9.2 -13.5 6.0 117 143 A N T 3 S+ 0 0 102 -3,-0.1 -1,-0.2 2,-0.1 -2,-0.1 0.552 88.7 114.3 -79.0 -10.0 12.0 -15.5 7.8 118 144 A F < - 0 0 8 -3,-0.6 2,-2.2 -4,-0.2 3,-0.4 -0.517 63.0-143.3 -80.5 112.9 12.9 -12.6 10.1 119 145 A P + 0 0 23 0, 0.0 -23,-0.4 0, 0.0 3,-0.2 -0.285 67.3 107.3 -82.8 60.9 12.0 -13.6 13.7 120 146 A I > + 0 0 0 -2,-2.2 3,-2.1 1,-0.1 6,-0.2 0.315 37.7 110.1-113.6 4.6 10.8 -10.3 15.1 121 147 A G T 3 S+ 0 0 8 -3,-0.4 -1,-0.1 1,-0.3 3,-0.0 0.611 77.2 53.4 -60.7 -16.0 7.0 -11.0 15.2 122 148 A H T 3 S+ 0 0 178 -3,-0.2 2,-1.6 1,-0.1 -1,-0.3 0.414 78.7 97.2 -98.8 1.7 7.0 -11.1 19.0 123 149 A L X + 0 0 9 -3,-2.1 3,-2.3 1,-0.2 -1,-0.1 -0.453 42.7 163.1 -90.8 65.0 8.6 -7.7 19.5 124 150 A K T 3 + 0 0 145 -2,-1.6 26,-0.4 1,-0.3 -1,-0.2 0.674 68.8 62.1 -60.3 -19.0 5.3 -5.8 20.1 125 151 A T T 3 S+ 0 0 38 -3,-0.2 -1,-0.3 24,-0.1 -2,-0.1 0.557 75.4 126.7 -81.1 -9.2 7.2 -2.9 21.6 126 152 A L < + 0 0 0 -3,-2.3 24,-0.3 -6,-0.2 -23,-0.2 -0.268 25.8 167.4 -60.5 127.5 9.2 -2.2 18.4 127 153 A K + 0 0 81 -24,-2.7 25,-3.0 1,-0.3 26,-1.9 0.677 66.8 34.9-106.6 -32.0 8.9 1.4 17.1 128 154 A E E -fg 104 153A 54 -25,-2.6 -23,-2.4 24,-0.2 2,-0.5 -0.988 54.1-176.9-135.2 128.1 11.7 1.4 14.5 129 155 A L E -fg 105 154A 0 24,-2.5 26,-2.4 -2,-0.4 2,-0.7 -0.978 7.6-170.9-120.8 115.6 13.0 -1.3 12.1 130 156 A N E +fg 106 155A 26 -25,-2.5 -23,-3.0 -2,-0.5 26,-0.1 -0.904 22.7 152.6-108.8 104.3 16.0 -0.4 10.0 131 157 A V + 0 0 0 24,-2.2 5,-0.2 -2,-0.7 3,-0.2 -0.097 26.1 145.6-119.0 31.7 16.7 -3.0 7.3 132 158 A A + 0 0 3 1,-0.2 -23,-1.6 -24,-0.1 26,-0.2 -0.229 56.3 32.1 -62.8 157.8 18.4 -0.6 4.8 133 159 A H S S+ 0 0 105 24,-1.8 -24,-0.4 -25,-0.2 -22,-0.3 0.941 94.1 118.1 58.4 52.7 21.3 -1.9 2.6 134 160 A N S S- 0 0 8 24,-0.8 -1,-0.2 23,-0.3 -21,-0.1 -0.512 75.0-101.5-129.2-159.8 20.1 -5.4 2.4 135 161 A L + 0 0 72 -23,-2.9 2,-0.2 -2,-0.2 -22,-0.1 0.037 58.8 145.6-120.4 24.2 19.0 -7.9 -0.3 136 162 A I + 0 0 2 -5,-0.2 24,-2.6 -24,-0.2 -22,-0.2 -0.466 21.7 179.8 -71.2 128.3 15.2 -7.8 0.1 137 163 A Q + 0 0 139 -24,-0.8 25,-0.8 -2,-0.2 2,-0.4 0.620 60.9 59.4-102.5 -18.3 13.4 -8.2 -3.3 138 164 A S - 0 0 66 -25,-0.3 -23,-0.2 23,-0.1 -1,-0.1 -0.927 53.4-161.8-120.8 138.5 9.8 -8.0 -2.1 139 165 A F + 0 0 2 -2,-0.4 2,-0.6 24,-0.4 -1,-0.1 0.281 53.4 128.5 -94.7 7.9 7.8 -5.3 -0.3 140 166 A K - 0 0 90 29,-0.1 -25,-0.2 1,-0.1 29,-0.1 -0.537 57.1-141.0 -66.0 111.9 5.2 -7.8 0.7 141 167 A L - 0 0 3 27,-2.3 30,-0.3 -2,-0.6 -2,-0.1 -0.669 18.9-119.5 -82.0 124.3 4.9 -7.2 4.5 142 168 A P > - 0 0 2 0, 0.0 3,-2.1 0, 0.0 4,-0.2 -0.143 23.7-106.1 -60.7 157.3 4.5 -10.5 6.3 143 169 A E G > S+ 0 0 106 1,-0.3 3,-2.1 2,-0.2 4,-0.2 0.783 112.9 73.1 -53.5 -31.7 1.4 -11.2 8.5 144 170 A Y G > S+ 0 0 37 1,-0.3 3,-2.0 2,-0.2 4,-0.5 0.674 75.4 80.6 -64.2 -15.3 3.5 -10.8 11.7 145 171 A F G X S+ 0 0 1 -3,-2.1 3,-1.3 1,-0.3 -1,-0.3 0.809 79.0 69.0 -58.8 -26.7 3.5 -7.0 11.0 146 172 A S G < S+ 0 0 38 -3,-2.1 -1,-0.3 1,-0.3 -2,-0.2 0.738 94.4 56.9 -62.5 -21.8 -0.0 -7.0 12.5 147 173 A N G < S+ 0 0 79 -3,-2.0 2,-1.3 -4,-0.2 -1,-0.3 0.681 90.0 77.7 -75.2 -21.6 1.8 -7.8 15.9 148 174 A L X + 0 0 1 -3,-1.3 3,-1.5 -4,-0.5 -1,-0.2 -0.469 52.1 154.2 -94.4 65.0 3.9 -4.7 15.5 149 175 A T T 3 S+ 0 0 75 -2,-1.3 -1,-0.2 1,-0.3 -24,-0.1 0.447 70.2 53.6 -76.4 -2.4 1.2 -2.1 16.6 150 176 A N T 3 S+ 0 0 84 -26,-0.4 -1,-0.3 -24,-0.3 2,-0.2 0.354 75.6 129.8-109.5 4.0 3.8 0.4 17.8 151 177 A L < + 0 0 6 -3,-1.5 28,-0.5 -6,-0.2 -24,-0.2 -0.412 16.4 155.9 -66.9 125.3 5.8 0.5 14.5 152 178 A E + 0 0 99 -25,-3.0 29,-2.7 1,-0.3 2,-0.4 0.499 60.9 44.1-125.5 -14.7 6.4 4.1 13.4 153 179 A H E +gh 128 181A 48 -26,-1.9 -24,-2.5 27,-0.2 2,-0.4 -0.977 53.6 175.5-138.6 124.9 9.5 3.8 11.2 154 180 A L E -gh 129 182A 0 27,-2.8 29,-2.3 -2,-0.4 2,-0.7 -0.966 10.3-165.8-128.0 114.7 10.4 1.3 8.5 155 181 A D E +gh 130 183A 22 -26,-2.4 -24,-2.2 -2,-0.4 29,-0.1 -0.884 25.1 153.2-105.8 109.4 13.6 1.7 6.5 156 182 A L + 0 0 1 27,-2.9 3,-0.4 -2,-0.7 5,-0.2 0.056 30.1 138.8-117.0 20.0 13.8 -0.5 3.4 157 183 A S + 0 0 8 1,-0.2 -24,-1.8 26,-0.1 -23,-0.3 -0.226 61.2 24.4 -64.1 155.9 16.1 1.9 1.4 158 184 A S S S+ 0 0 27 27,-1.7 -24,-0.8 -26,-0.2 -1,-0.2 0.899 94.0 120.7 53.2 47.8 19.0 0.5 -0.6 159 185 A N S S- 0 0 6 -3,-0.4 -22,-0.1 26,-0.3 -24,-0.1 -0.250 76.9 -96.1-113.5-152.2 17.4 -3.0 -1.1 160 186 A K + 0 0 107 -24,-2.6 2,-0.5 27,-0.1 27,-0.1 -0.043 64.1 144.3-123.5 31.0 16.5 -4.9 -4.3 161 187 A I + 0 0 0 -5,-0.2 -23,-0.1 1,-0.2 -24,-0.1 -0.606 19.8 174.3 -80.9 121.2 12.8 -4.0 -4.5 162 188 A Q + 0 0 102 -25,-0.8 28,-2.3 -2,-0.5 29,-1.3 0.636 62.1 22.3 -98.5 -18.9 11.6 -3.6 -8.1 163 189 A S E -n 191 0C 19 -26,-0.4 2,-0.5 26,-0.2 -24,-0.4 -0.966 53.2-142.9-146.5 156.3 7.8 -3.1 -7.5 164 190 A I E -n 192 0C 0 27,-2.0 29,-3.2 -2,-0.3 2,-0.2 -0.977 30.6-168.2-117.9 112.4 5.1 -2.1 -5.0 165 191 A Y > - 0 0 110 -2,-0.5 3,-1.0 27,-0.2 4,-0.5 -0.626 32.7-111.2 -94.7 159.9 2.1 -4.3 -5.5 166 192 A C G > S+ 0 0 34 1,-0.2 3,-0.7 -2,-0.2 32,-0.1 0.875 116.1 53.2 -53.5 -44.6 -1.4 -3.8 -4.0 167 193 A T G > S+ 0 0 94 1,-0.2 3,-1.8 2,-0.1 4,-0.3 0.709 87.7 84.8 -66.3 -22.6 -1.1 -6.8 -1.7 168 194 A D G < S+ 0 0 4 -3,-1.0 -27,-2.3 1,-0.3 3,-0.3 0.837 97.5 34.6 -53.5 -42.8 2.2 -5.6 -0.2 169 195 A L G X> S+ 0 0 1 -3,-0.7 3,-1.5 -4,-0.5 4,-0.9 0.310 83.5 114.8 -97.1 9.0 0.7 -3.3 2.4 170 196 A R H X> S+ 0 0 174 -3,-1.8 3,-0.9 1,-0.3 4,-0.5 0.849 72.7 55.8 -45.8 -45.4 -2.4 -5.5 3.1 171 197 A V H >4 S+ 0 0 3 -3,-0.3 3,-0.6 -4,-0.3 -1,-0.3 0.839 105.9 51.9 -62.0 -31.0 -1.3 -6.2 6.6 172 198 A L H X4 S+ 0 0 3 -3,-1.5 3,-1.6 1,-0.2 -1,-0.2 0.688 89.7 76.9 -82.0 -18.1 -1.1 -2.4 7.5 173 199 A H H << S+ 0 0 60 -4,-0.9 -1,-0.2 -3,-0.9 -2,-0.2 0.773 92.3 54.2 -64.0 -27.4 -4.6 -1.6 6.2 174 200 A Q T << S+ 0 0 128 -3,-0.6 -1,-0.3 -4,-0.5 -2,-0.1 0.191 90.6 87.1 -90.6 15.1 -6.2 -3.1 9.4 175 201 A M X + 0 0 23 -3,-1.6 3,-1.3 1,-0.1 -1,-0.1 -0.727 45.6 171.7-123.8 81.8 -4.1 -0.9 11.7 176 202 A P T 3 S+ 0 0 117 0, 0.0 -1,-0.1 0, 0.0 -2,-0.0 0.673 76.1 63.2 -61.1 -25.6 -5.7 2.5 12.4 177 203 A L T 3 S+ 0 0 145 2,-0.0 -2,-0.0 -28,-0.0 -28,-0.0 0.720 79.2 120.9 -73.0 -19.5 -3.2 3.6 15.1 178 204 A L < + 0 0 12 -3,-1.3 2,-0.1 -6,-0.2 23,-0.1 -0.102 30.6 168.2 -50.8 132.2 -0.4 3.5 12.5 179 205 A N - 0 0 63 -28,-0.5 2,-0.3 2,-0.0 23,-0.2 -0.656 28.5-176.8-141.6 82.6 1.5 6.7 11.8 180 206 A L E - i 0 202A 1 21,-2.1 23,-1.4 -2,-0.1 24,-1.1 -0.648 31.0-154.9-101.7 135.0 4.3 5.3 9.7 181 207 A S E -hi 153 204A 10 -29,-2.7 -27,-2.8 -2,-0.3 2,-0.5 -0.930 24.5-168.2 -99.1 126.7 7.5 6.7 8.1 182 208 A L E -hi 154 205A 3 22,-2.7 24,-2.4 -2,-0.5 2,-0.7 -0.963 12.4-168.0-126.9 116.5 8.4 4.6 5.2 183 209 A D E +hi 155 206A 37 -29,-2.3 -27,-2.9 -2,-0.5 -26,-0.1 -0.914 24.3 151.2-106.4 112.4 11.7 4.7 3.3 184 210 A L + 0 0 0 22,-2.6 3,-0.4 -2,-0.7 5,-0.2 0.022 35.7 128.9-120.8 22.2 11.7 2.8 -0.0 185 211 A S + 0 0 7 1,-0.2 -27,-1.7 25,-0.1 -26,-0.3 -0.233 55.5 36.4 -75.7 167.8 14.3 5.0 -1.7 186 212 A L S S+ 0 0 85 22,-1.9 -1,-0.2 -29,-0.2 24,-0.2 0.820 87.9 129.1 56.7 35.4 17.5 3.8 -3.4 187 213 A N S S- 0 0 4 -3,-0.4 2,-2.1 21,-0.3 -1,-0.2 -0.872 73.8-115.4-114.3 150.4 15.7 0.7 -4.7 188 214 A P + 0 0 35 0, 0.0 2,-0.5 0, 0.0 22,-0.1 -0.257 61.8 156.9 -77.3 52.0 15.6 -0.5 -8.4 189 215 A M + 0 0 0 -2,-2.1 22,-2.4 -5,-0.2 -26,-0.2 -0.702 17.4 154.4 -91.8 120.0 11.9 0.2 -8.3 190 216 A N + 0 0 86 -28,-2.3 23,-0.4 -2,-0.5 2,-0.4 0.384 58.8 59.3-120.5 0.3 10.2 0.8 -11.7 191 217 A F E +n 163 0C 82 -29,-1.3 -27,-2.0 21,-0.1 2,-0.5 -0.979 44.3 177.1-140.1 125.1 6.6 -0.2 -10.9 192 218 A I E -n 164 0C 6 -2,-0.4 -27,-0.2 22,-0.2 3,-0.1 -0.992 30.8-134.7-121.1 121.0 3.9 0.9 -8.5 193 219 A Q > - 0 0 66 -29,-3.2 3,-1.5 -2,-0.5 -2,-0.0 -0.463 31.2 -94.9 -73.8 140.4 0.6 -1.0 -8.9 194 220 A P T 3 S+ 0 0 82 0, 0.0 -28,-0.2 0, 0.0 -1,-0.1 -0.295 111.5 19.7 -52.0 136.4 -2.7 1.1 -8.9 195 221 A G T 3 S+ 0 0 36 2,-0.2 3,-0.2 -3,-0.1 -2,-0.1 0.600 80.4 134.9 79.3 14.5 -4.2 1.2 -5.4 196 222 A A S < S+ 0 0 0 -3,-1.5 2,-0.7 1,-0.3 -27,-0.3 0.828 72.7 42.5 -66.7 -36.5 -1.0 0.2 -3.6 197 223 A F S S+ 0 0 4 22,-0.4 2,-0.7 2,-0.0 25,-0.4 -0.906 74.1 177.0-109.3 97.5 -1.4 2.9 -1.0 198 224 A K - 0 0 89 -2,-0.7 25,-0.1 -3,-0.2 22,-0.1 -0.864 68.9 -46.5-107.9 101.3 -5.1 2.8 0.1 199 225 A E S S+ 0 0 122 -2,-0.7 24,-0.1 1,-0.2 -1,-0.1 0.470 86.7 152.4 56.7 15.0 -5.7 5.3 2.9 200 226 A I - 0 0 9 1,-0.1 24,-2.1 23,-0.1 2,-1.1 -0.337 51.2-118.4 -64.8 148.5 -2.7 4.3 5.1 201 227 A R + 0 0 84 22,-0.2 -21,-2.1 -23,-0.1 2,-0.8 -0.785 39.0 173.6 -91.9 92.9 -1.3 7.1 7.3 202 228 A L E -i 180 0A 0 -2,-1.1 25,-0.3 22,-0.4 -21,-0.2 -0.898 14.6-171.5 -98.5 106.2 2.2 7.5 6.0 203 229 A K E S+ 0 0 73 -23,-1.4 24,-2.6 -2,-0.8 25,-1.6 0.899 79.6 15.2 -61.6 -41.4 3.7 10.4 7.9 204 230 A E E -ij 181 228A 44 -24,-1.1 -22,-2.7 23,-0.2 2,-0.4 -0.992 66.3-173.7-136.9 142.1 6.7 10.2 5.5 205 231 A L E -ij 182 229A 0 23,-2.0 25,-2.1 -2,-0.3 2,-0.5 -0.976 4.0-168.5-137.6 121.3 7.2 8.4 2.2 206 232 A A E +ij 183 230A 7 -24,-2.4 -22,-2.6 -2,-0.4 25,-0.2 -0.956 25.8 147.6-116.4 120.9 10.5 8.2 0.4 207 233 A L + 0 0 0 23,-2.8 3,-0.5 -2,-0.5 5,-0.2 0.035 34.4 130.1-134.5 21.0 10.6 6.9 -3.2 208 234 A D + 0 0 18 1,-0.2 -22,-1.9 22,-0.1 -21,-0.3 -0.370 60.9 27.0 -78.2 158.5 13.5 9.0 -4.5 209 235 A T S S+ 0 0 49 23,-2.3 -1,-0.2 -24,-0.2 25,-0.2 0.836 94.2 115.7 58.7 38.0 16.5 7.7 -6.4 210 236 A N S S- 0 0 12 -3,-0.5 -20,-0.1 22,-0.3 -1,-0.1 -0.031 80.6 -96.1-105.7-147.2 14.6 4.7 -7.8 211 237 A Q + 0 0 99 -22,-2.4 2,-0.5 23,-0.1 23,-0.1 -0.123 63.5 147.4-130.3 36.9 13.7 3.9 -11.4 212 238 A L + 0 0 0 -5,-0.2 -22,-0.1 1,-0.2 3,-0.1 -0.622 20.6 170.3 -84.1 123.2 10.1 5.3 -11.7 213 239 A K S S- 0 0 139 -2,-0.5 24,-2.7 -23,-0.4 2,-0.3 0.640 73.4 -6.1 -95.4 -22.8 9.0 6.7 -15.0 214 240 A S - 0 0 49 -24,-0.2 -1,-0.3 22,-0.2 -22,-0.2 -0.977 56.9-140.9-161.1 166.4 5.4 7.1 -13.9 215 241 A V - 0 0 16 -2,-0.3 31,-0.2 27,-0.2 30,-0.1 -0.925 39.9 -91.0-129.2 155.4 2.9 6.4 -11.1 216 242 A P > - 0 0 21 0, 0.0 3,-1.8 0, 0.0 4,-0.2 -0.383 51.0 -94.7 -61.6 145.0 -0.8 5.3 -11.4 217 243 A D T 3 S+ 0 0 125 1,-0.2 26,-0.0 2,-0.1 25,-0.0 -0.368 112.0 13.8 -54.6 134.4 -3.4 8.1 -11.5 218 244 A G T > S+ 0 0 26 -3,-0.1 3,-1.5 -24,-0.1 4,-0.4 0.502 82.8 139.5 78.0 6.3 -4.8 8.7 -8.0 219 245 A I T < S+ 0 0 4 -3,-1.8 -22,-0.4 1,-0.3 3,-0.2 0.787 78.9 30.0 -57.7 -32.7 -2.0 6.7 -6.3 220 246 A F T > S+ 0 0 4 -4,-0.2 3,-1.3 1,-0.1 -1,-0.3 0.383 91.4 100.1-104.8 0.9 -1.6 9.2 -3.5 221 247 A D T < S+ 0 0 104 -3,-1.5 -2,-0.1 1,-0.3 -1,-0.1 0.727 85.2 44.8 -67.5 -24.1 -5.2 10.5 -3.3 222 248 A R T 3 S+ 0 0 137 -4,-0.4 -1,-0.3 -25,-0.4 -2,-0.1 0.425 81.1 125.9-101.3 1.2 -6.2 8.4 -0.3 223 249 A L < - 0 0 25 -3,-1.3 2,-0.5 -24,-0.1 3,-0.2 -0.372 53.5-139.5 -62.6 134.9 -3.0 9.0 1.8 224 250 A T - 0 0 57 -24,-2.1 -22,-0.4 1,-0.2 -1,-0.1 -0.853 69.2 -16.6-102.7 126.3 -3.9 10.2 5.3 225 251 A S S S- 0 0 73 -2,-0.5 2,-0.3 1,-0.2 -1,-0.2 0.813 75.1-178.9 51.2 41.2 -1.8 13.0 7.0 226 252 A L + 0 0 14 -3,-0.2 -23,-0.2 1,-0.2 -1,-0.2 -0.573 8.0 174.4 -64.3 128.9 1.2 12.7 4.7 227 253 A Q + 0 0 107 -24,-2.6 2,-0.4 1,-0.3 -23,-0.2 0.777 61.3 15.5-105.4 -41.3 3.8 15.3 5.9 228 254 A K E +j 204 0A 84 -25,-1.6 -23,-2.0 -26,-0.2 2,-0.4 -0.999 58.2 179.8-140.2 138.3 6.9 14.7 3.7 229 255 A I E -jk 205 257A 0 27,-2.3 29,-2.7 -2,-0.4 2,-0.5 -0.999 13.0-155.5-139.8 136.7 7.5 12.8 0.4 230 256 A W E +j 206 0A 64 -25,-2.1 -23,-2.8 -2,-0.4 29,-0.1 -0.966 29.6 148.7-110.2 126.4 10.7 12.3 -1.6 231 257 A L + 0 0 0 -2,-0.5 3,-0.2 27,-0.5 31,-0.1 0.339 34.0 120.2-134.5 -0.8 10.2 11.6 -5.4 232 258 A H + 0 0 42 26,-0.5 -23,-2.3 1,-0.2 -22,-0.3 -0.006 56.5 40.8 -69.9 171.4 13.3 13.2 -6.9 233 259 A T S S+ 0 0 91 27,-0.5 -1,-0.2 1,-0.2 -23,-0.1 0.864 83.4 124.6 53.6 40.9 16.1 11.5 -9.0 234 260 A N S S- 0 0 9 -3,-0.2 2,-2.3 28,-0.2 28,-0.3 -0.953 73.8-113.5-118.6 147.8 13.6 9.3 -10.9 235 261 A P - 0 0 50 0, 0.0 28,-0.1 0, 0.0 -3,-0.0 -0.355 45.4-168.1 -77.4 63.5 13.4 9.3 -14.7 236 262 A W B -o 263 0D 0 -2,-2.3 28,-2.7 26,-0.7 2,-0.9 -0.269 19.1-137.1 -60.6 130.6 9.9 10.9 -14.8 237 263 A D - 0 0 50 -24,-2.7 -1,-0.1 26,-0.2 26,-0.1 -0.810 19.8-173.0 -86.3 104.8 8.1 10.8 -18.2 238 264 A b + 0 0 26 -2,-0.9 -1,-0.1 26,-0.3 2,-0.1 0.214 35.8 130.7 -92.4 17.7 6.6 14.3 -18.4 239 265 A S > - 0 0 54 2,-0.0 4,-2.5 1,-0.0 5,-0.2 -0.430 62.2 -87.5 -62.5 141.6 4.6 13.8 -21.5 240 266 A c T 4 S+ 0 0 56 1,-0.3 -2,-0.1 2,-0.2 -1,-0.0 -0.806 104.8 15.4 -96.8 143.5 1.0 14.9 -21.2 241 267 A P T >4 S+ 0 0 105 0, 0.0 3,-1.7 0, 0.0 4,-0.5 -0.978 119.3 66.0 -89.6 8.8 -1.5 13.6 -20.2 242 268 A R T 34 S+ 0 0 142 1,-0.3 3,-0.4 2,-0.1 4,-0.4 0.924 108.5 40.9 -52.1 -49.4 0.6 10.9 -18.6 243 269 A I T 3X S+ 0 0 3 -4,-2.5 4,-3.0 1,-0.2 5,-0.4 0.404 88.7 100.6 -80.8 3.2 2.2 13.3 -16.1 244 270 A D H <> S+ 0 0 46 -3,-1.7 4,-2.3 -5,-0.2 5,-0.2 0.943 83.3 42.3 -58.1 -54.4 -1.1 15.2 -15.5 245 271 A Y H > S+ 0 0 29 -4,-0.5 4,-2.5 -3,-0.4 -1,-0.2 0.941 119.1 43.3 -56.2 -52.9 -2.0 13.5 -12.1 246 272 A L H > S+ 0 0 5 -4,-0.4 4,-2.8 2,-0.2 5,-0.2 0.909 114.2 48.7 -66.9 -42.7 1.5 13.6 -10.7 247 273 A S H X S+ 0 0 0 -4,-3.0 4,-2.0 1,-0.2 -1,-0.2 0.916 114.4 47.4 -60.8 -42.9 2.3 17.2 -11.8 248 274 A R H X S+ 0 0 162 -4,-2.3 4,-2.5 -5,-0.4 -2,-0.2 0.917 114.2 46.9 -61.2 -45.2 -1.1 18.4 -10.4 249 275 A W H X S+ 0 0 22 -4,-2.5 4,-2.8 -5,-0.2 -2,-0.2 0.912 113.4 46.7 -68.4 -42.7 -0.5 16.5 -7.1 250 276 A L H < S+ 0 0 0 -4,-2.8 7,-0.2 2,-0.2 -1,-0.2 0.829 112.0 52.0 -69.5 -33.2 3.1 17.8 -6.6 251 277 A N H >< S+ 0 0 75 -4,-2.0 3,-1.4 -5,-0.2 -2,-0.2 0.974 115.0 41.0 -62.3 -55.4 2.0 21.3 -7.4 252 278 A K H 3< S+ 0 0 162 -4,-2.5 3,-0.4 1,-0.3 -2,-0.2 0.905 123.4 39.7 -58.8 -44.6 -0.8 21.2 -4.9 253 279 A N T >X S+ 0 0 13 -4,-2.8 3,-2.2 -5,-0.2 4,-0.9 -0.018 74.9 130.3 -97.9 29.4 1.3 19.4 -2.3 254 280 A S G X4 + 0 0 43 -3,-1.4 3,-0.5 1,-0.3 -1,-0.2 0.801 66.4 62.3 -56.4 -32.0 4.5 21.3 -3.0 255 281 A Q G 34 S+ 0 0 124 -3,-0.4 -1,-0.3 1,-0.2 -2,-0.1 0.735 104.6 50.0 -65.2 -23.2 5.1 22.0 0.8 256 282 A K G <4 S+ 0 0 46 -3,-2.2 -27,-2.3 -6,-0.1 2,-0.4 0.703 87.4 101.0 -86.9 -22.4 5.3 18.3 1.3 257 283 A E B << -k 229 0A 12 -4,-0.9 2,-0.6 -3,-0.5 -27,-0.2 -0.516 55.9-160.3 -74.6 123.9 7.9 17.6 -1.5 258 284 A Q - 0 0 58 -29,-2.7 -26,-0.5 -2,-0.4 -27,-0.5 -0.914 68.1 -6.1-102.8 118.6 11.5 17.2 -0.3 259 285 A G S S- 0 0 44 -2,-0.6 2,-0.5 -29,-0.1 -30,-0.1 -0.291 98.6 -74.4 80.2-178.5 13.8 17.8 -3.1 260 286 A S - 0 0 30 -2,-0.1 -27,-0.5 -30,-0.0 2,-0.2 -0.928 29.4-145.1-126.9 109.8 12.6 18.3 -6.7 261 287 A A - 0 0 0 -2,-0.5 9,-3.1 -29,-0.2 10,-0.5 -0.535 31.3-162.6 -64.8 131.3 11.3 15.6 -9.0 262 288 A K B -P 269 0E 99 -28,-0.3 -26,-0.7 7,-0.3 2,-0.2 -0.896 19.9-103.5-126.2 152.2 12.4 16.6 -12.5 263 289 A b B >> -o 236 0D 6 5,-2.7 4,-2.4 -2,-0.3 3,-0.7 -0.500 38.3-113.7 -74.6 134.3 11.4 15.7 -16.0 264 290 A S T 34 S+ 0 0 67 -28,-2.7 -26,-0.3 -2,-0.2 -1,-0.1 -0.464 99.5 12.4 -64.2 135.5 13.7 13.3 -17.9 265 291 A G T 34 S+ 0 0 93 1,-0.1 -1,-0.2 -2,-0.1 -28,-0.1 0.058 133.5 43.8 88.1 -27.7 15.3 15.1 -20.8 266 292 A S T <4 S- 0 0 88 -3,-0.7 -2,-0.2 2,-0.1 -1,-0.1 0.680 85.5-139.8-118.4 -33.9 14.4 18.6 -19.8 267 293 A G < + 0 0 37 -4,-2.4 -3,-0.1 1,-0.3 3,-0.1 0.458 47.8 150.0 82.0 2.0 15.0 18.9 -16.1 268 294 A K - 0 0 104 -6,-0.1 -5,-2.7 -5,-0.1 -1,-0.3 -0.457 58.1-100.5 -65.8 135.2 11.9 21.0 -15.6 269 295 A P B > -P 262 0E 43 0, 0.0 3,-1.3 0, 0.0 4,-0.4 -0.361 21.9-136.2 -59.0 134.4 10.4 20.4 -12.1 270 296 A V G > S+ 0 0 0 -9,-3.1 3,-1.5 1,-0.3 -19,-0.2 0.877 105.3 58.8 -57.4 -39.1 7.5 18.0 -12.2 271 297 A R G 3 S+ 0 0 64 -10,-0.5 -1,-0.3 1,-0.3 -17,-0.1 0.673 102.2 55.1 -64.8 -17.9 5.5 20.3 -9.8 272 298 A S G < S+ 0 0 45 -3,-1.3 2,-0.3 2,-0.0 -1,-0.3 0.495 83.9 109.3 -95.5 -4.3 5.9 23.1 -12.4 273 299 A I < - 0 0 21 -3,-1.5 2,-0.4 -4,-0.4 -22,-0.1 -0.558 44.6-174.7 -74.7 132.0 4.3 21.0 -15.3 274 300 A I - 0 0 128 -2,-0.3 -34,-0.1 -26,-0.0 -30,-0.1 -0.985 16.1-143.7-126.8 118.6 0.8 22.0 -16.4 275 301 A c 0 0 12 -2,-0.4 -36,-0.0 1,-0.1 -2,-0.0 -0.550 360.0 360.0 -79.2 145.9 -0.8 19.8 -19.0 276 302 A P 0 0 184 0, 0.0 -1,-0.1 0, 0.0 0, 0.0 0.736 360.0 360.0 -67.2 360.0 -3.0 21.5 -21.8