==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER LYASE 18-APR-05 1ZE8 . COMPND 2 MOLECULE: CARBONIC ANHYDRASE II; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR V.MENCHISE,G.DE SIMONE,V.ALTERIO,A.DI FIORE,C.PEDONE,A.SCOZZ . 258 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 12094.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 160 62.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 18 7.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 55 21.3 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 24 9.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 33 12.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 16 6.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 2 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 3 2 0 1 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 3 A H 0 0 241 0, 0.0 3,-0.1 0, 0.0 2,-0.0 0.000 360.0 360.0 360.0 127.7 12.1 -0.2 6.0 2 4 A H - 0 0 132 1,-0.2 0, 0.0 0, 0.0 0, 0.0 -0.111 360.0 -52.2 -87.4-173.4 9.6 0.7 8.7 3 5 A W + 0 0 46 1,-0.1 -1,-0.2 11,-0.1 2,-0.2 -0.156 62.7 150.2 -59.4 152.5 7.7 -1.3 11.3 4 6 A G - 0 0 8 5,-3.1 9,-0.1 2,-0.1 10,-0.1 -0.623 55.9 -91.5-153.6-147.2 5.6 -4.4 10.3 5 7 A Y S S+ 0 0 36 5,-0.2 5,-0.2 -2,-0.2 237,-0.1 0.204 82.7 108.4-129.8 11.5 4.5 -7.7 11.7 6 8 A G S > S- 0 0 41 4,-0.1 4,-1.1 1,-0.1 -2,-0.1 -0.040 85.7 -94.3 -80.5-173.8 7.4 -9.8 10.5 7 9 A K T 4 S+ 0 0 168 1,-0.2 -1,-0.1 2,-0.2 5,-0.1 0.818 123.8 37.2 -72.9 -31.5 10.2 -11.5 12.4 8 10 A H T 4 S+ 0 0 162 1,-0.1 -1,-0.2 5,-0.0 -5,-0.0 0.641 132.4 24.5 -96.6 -16.6 12.6 -8.6 11.8 9 11 A N T 4 S+ 0 0 58 -6,-0.1 -5,-3.1 4,-0.0 -2,-0.2 0.187 96.8 115.5-132.2 14.0 10.2 -5.6 12.1 10 12 A G S >X S- 0 0 2 -4,-1.1 3,-2.9 -5,-0.2 4,-0.8 0.024 84.9 -63.9 -77.4-172.8 7.3 -7.0 14.2 11 13 A P T 34 S+ 0 0 25 0, 0.0 4,-0.5 0, 0.0 3,-0.3 0.735 128.9 58.5 -40.2 -40.1 5.9 -6.1 17.7 12 14 A E T 34 S+ 0 0 146 1,-0.2 -5,-0.0 2,-0.1 -2,-0.0 0.534 108.8 47.1 -74.5 -5.4 9.1 -7.1 19.5 13 15 A H T X4 S+ 0 0 57 -3,-2.9 3,-1.6 -9,-0.1 4,-0.5 0.610 87.8 85.2-107.0 -20.1 11.1 -4.5 17.5 14 16 A W G >X S+ 0 0 6 -4,-0.8 4,-2.6 -3,-0.3 3,-0.8 0.811 74.8 70.0 -54.5 -37.7 8.7 -1.5 17.8 15 17 A H G 34 S+ 0 0 65 -4,-0.5 -1,-0.3 1,-0.2 6,-0.1 0.769 88.7 67.4 -55.3 -25.6 10.1 -0.3 21.1 16 18 A K G <4 S+ 0 0 128 -3,-1.6 -1,-0.2 1,-0.2 -2,-0.2 0.917 116.2 21.6 -64.0 -45.1 13.3 0.8 19.3 17 19 A D T <4 S+ 0 0 126 -3,-0.8 -2,-0.2 -4,-0.5 -1,-0.2 0.710 136.7 39.0 -91.9 -25.1 11.7 3.5 17.2 18 20 A F >< - 0 0 59 -4,-2.6 3,-2.3 1,-0.1 -1,-0.2 -0.719 67.1-179.4-129.1 80.0 8.8 4.0 19.5 19 21 A P G > S+ 0 0 96 0, 0.0 3,-2.1 0, 0.0 -1,-0.1 0.738 75.7 74.1 -49.8 -31.6 10.0 3.6 23.2 20 22 A I G > + 0 0 58 1,-0.3 3,-3.0 2,-0.2 -5,-0.1 0.598 69.7 92.4 -63.8 -6.0 6.5 4.1 24.6 21 23 A A G < S+ 0 0 6 -3,-2.3 -1,-0.3 1,-0.3 -6,-0.1 0.766 90.0 45.1 -57.2 -23.4 5.9 0.6 23.3 22 24 A K G < S+ 0 0 141 -3,-2.1 -1,-0.3 -7,-0.1 -2,-0.2 0.071 96.3 133.7-106.1 20.5 7.0 -0.4 26.8 23 25 A G < - 0 0 15 -3,-3.0 3,-0.4 1,-0.1 -3,-0.0 0.277 70.0-101.0 -61.2-171.3 4.8 2.3 28.4 24 26 A E S S+ 0 0 124 1,-0.2 226,-0.3 225,-0.1 -1,-0.1 0.585 113.2 32.5 -91.8 -14.4 2.4 2.3 31.3 25 27 A R S S+ 0 0 47 224,-0.1 -1,-0.2 168,-0.1 2,-0.2 -0.339 80.5 155.5-141.1 57.7 -0.9 2.0 29.4 26 28 A Q - 0 0 2 -3,-0.4 220,-0.1 221,-0.4 170,-0.1 -0.480 32.6 -97.3 -86.4 156.8 -0.2 0.0 26.2 27 29 A S S S+ 0 0 0 168,-0.5 2,-0.2 -2,-0.2 -2,-0.0 -0.904 79.1 39.1-128.5 156.2 -2.7 -2.0 24.2 28 30 A P + 0 0 0 0, 0.0 218,-3.5 0, 0.0 2,-0.3 0.581 65.7 175.5 -81.9-177.7 -4.0 -4.5 23.6 29 31 A V - 0 0 1 216,-0.3 77,-1.1 -2,-0.2 2,-0.3 -0.950 35.9 -99.2-143.1 161.4 -4.4 -6.4 26.8 30 32 A D E -a 106 0A 30 216,-0.4 2,-0.9 -2,-0.3 77,-0.2 -0.648 33.5-136.5 -81.9 139.3 -5.9 -9.7 28.0 31 33 A I E -a 107 0A 0 75,-2.9 77,-1.7 -2,-0.3 2,-1.3 -0.829 11.7-160.7-101.4 100.1 -9.3 -9.2 29.5 32 34 A D >> - 0 0 65 -2,-0.9 4,-2.0 1,-0.2 3,-1.2 -0.679 5.0-163.4 -80.5 97.8 -9.6 -11.3 32.7 33 35 A T T 34 S+ 0 0 41 -2,-1.3 -1,-0.2 1,-0.3 222,-0.0 0.781 85.6 53.1 -53.3 -34.1 -13.3 -11.5 33.0 34 36 A H T 34 S+ 0 0 166 1,-0.2 -1,-0.3 -3,-0.1 -2,-0.1 0.762 112.8 43.7 -76.1 -24.2 -13.2 -12.6 36.6 35 37 A T T <4 S+ 0 0 105 -3,-1.2 -2,-0.2 2,-0.1 -1,-0.2 0.712 91.1 98.5 -91.8 -22.4 -11.0 -9.7 37.6 36 38 A A < - 0 0 17 -4,-2.0 2,-0.4 218,-0.1 218,-0.2 -0.450 68.8-144.1 -65.3 133.5 -13.0 -7.1 35.6 37 39 A K E -c 254 0B 137 216,-1.6 218,-2.9 -2,-0.1 -2,-0.1 -0.862 13.7-112.3-109.4 137.4 -15.3 -5.3 37.9 38 40 A Y E -c 255 0B 109 -2,-0.4 218,-0.2 216,-0.2 220,-0.1 -0.363 31.2-153.4 -59.4 136.4 -18.9 -4.1 37.2 39 41 A D > - 0 0 29 216,-2.8 3,-1.2 1,-0.1 -1,-0.1 -0.917 17.3-174.8-121.7 106.5 -18.9 -0.3 37.2 40 42 A P T 3 S+ 0 0 97 0, 0.0 -1,-0.1 0, 0.0 216,-0.0 0.690 80.4 73.2 -71.3 -17.3 -22.2 1.4 38.1 41 43 A S T 3 S+ 0 0 86 2,-0.0 2,-0.4 40,-0.0 -2,-0.0 0.452 76.0 105.9 -77.0 3.4 -20.7 4.9 37.4 42 44 A L < - 0 0 29 -3,-1.2 3,-0.1 213,-0.1 213,-0.0 -0.689 64.6-143.1 -86.6 133.1 -20.9 4.0 33.7 43 45 A K - 0 0 120 37,-1.6 37,-0.3 -2,-0.4 39,-0.1 -0.497 40.7 -75.7 -88.6 161.7 -23.6 5.7 31.7 44 46 A P - 0 0 117 0, 0.0 36,-0.5 0, 0.0 2,-0.2 -0.360 54.9-115.4 -58.6 134.0 -25.5 3.8 28.9 45 47 A L - 0 0 23 34,-0.3 2,-0.5 141,-0.1 34,-0.2 -0.489 29.0-154.8 -71.4 140.9 -23.2 3.6 25.9 46 48 A S E +D 78 0B 40 32,-3.2 32,-2.8 -2,-0.2 2,-0.6 -0.946 15.8 178.2-125.5 113.8 -24.5 5.5 22.8 47 49 A V E +D 77 0B 33 -2,-0.5 2,-0.6 30,-0.2 30,-0.2 -0.948 3.6 178.5-114.5 113.1 -23.5 4.6 19.3 48 50 A S E +D 76 0B 38 28,-2.6 28,-1.6 -2,-0.6 27,-0.4 -0.827 19.4 149.1-118.4 92.9 -25.2 6.8 16.7 49 51 A Y > + 0 0 4 -2,-0.6 3,-1.5 26,-0.2 130,-0.2 0.260 37.2 111.8-105.9 11.9 -24.0 5.8 13.2 50 52 A D T 3 S+ 0 0 93 1,-0.3 -1,-0.2 128,-0.1 129,-0.0 0.870 86.4 36.1 -51.0 -45.3 -27.3 6.8 11.4 51 53 A Q T 3 S+ 0 0 110 -3,-0.2 -1,-0.3 2,-0.1 -2,-0.1 0.334 85.8 141.1 -93.3 6.7 -25.7 9.7 9.6 52 54 A A < - 0 0 21 -3,-1.5 2,-0.4 1,-0.1 23,-0.1 -0.167 33.9-162.0 -52.0 138.6 -22.3 8.1 9.0 53 55 A T - 0 0 45 16,-0.3 16,-2.6 21,-0.2 2,-0.1 -0.901 1.6-157.5-131.8 105.1 -20.8 8.8 5.6 54 56 A S E +E 68 0B 2 -2,-0.4 121,-0.6 122,-0.3 14,-0.3 -0.428 12.8 177.2 -76.3 153.2 -18.0 6.6 4.3 55 57 A L E - 0 0 77 12,-3.0 118,-2.0 1,-0.4 2,-0.3 0.687 54.2 -7.9-123.5 -47.6 -15.7 8.0 1.6 56 58 A R E -EF 67 172B 87 11,-0.9 11,-3.0 116,-0.3 2,-0.4 -0.979 47.7-135.0-154.5 159.7 -13.0 5.6 0.7 57 59 A I E -EF 66 171B 0 114,-2.4 114,-2.4 -2,-0.3 2,-0.4 -0.978 28.8-170.9-120.6 136.1 -11.3 2.3 1.5 58 60 A L E -EF 65 170B 30 7,-2.4 7,-3.0 -2,-0.4 2,-0.8 -0.981 26.1-145.2-135.3 142.5 -7.5 2.1 1.6 59 61 A N E +E 64 0B 0 110,-2.5 109,-3.1 -2,-0.4 5,-0.2 -0.896 21.3 178.4-102.5 102.9 -4.8 -0.6 1.9 60 62 A N - 0 0 50 3,-1.4 4,-0.1 -2,-0.8 -1,-0.1 0.243 53.5-101.6 -92.4 13.8 -2.1 1.1 3.9 61 63 A G S S+ 0 0 6 2,-0.5 3,-0.1 166,-0.2 106,-0.1 0.473 117.7 59.1 83.1 0.5 0.2 -1.9 4.0 62 64 A H S S- 0 0 41 1,-0.6 2,-0.3 -58,-0.1 -1,-0.1 0.483 124.3 -41.5-130.0 -22.9 -0.8 -2.9 7.6 63 65 A A S S- 0 0 5 164,-0.1 -3,-1.4 165,-0.1 -1,-0.6 -0.907 72.3 -78.2 179.5-163.4 -4.5 -3.4 7.1 64 66 A F E -E 59 0B 0 -2,-0.3 2,-0.5 29,-0.2 29,-0.4 -0.990 34.6-149.6-127.8 136.2 -7.3 -1.7 5.2 65 67 A N E -E 58 0B 19 -7,-3.0 -7,-2.4 -2,-0.4 2,-0.8 -0.890 8.7-158.6-108.0 129.2 -9.1 1.5 6.3 66 68 A V E -EG 57 91B 0 25,-2.6 25,-1.6 -2,-0.5 2,-0.3 -0.923 29.6-155.7 -99.5 109.3 -12.7 2.4 5.6 67 69 A E E -EG 56 90B 47 -11,-3.0 -12,-3.0 -2,-0.8 -11,-0.9 -0.651 7.6-157.6 -92.3 145.6 -12.5 6.2 6.1 68 70 A F E -E 54 0B 10 21,-2.5 2,-0.8 -2,-0.3 -14,-0.2 -0.813 27.9-103.8-119.7 160.4 -15.4 8.4 6.9 69 71 A D + 0 0 54 -16,-2.6 3,-0.3 -2,-0.3 -16,-0.3 -0.741 39.4 172.4 -82.6 109.8 -16.2 12.1 6.5 70 72 A D + 0 0 41 -2,-0.8 -1,-0.1 1,-0.2 17,-0.1 -0.016 45.2 108.2-110.2 30.8 -15.6 13.6 10.0 71 73 A S S S+ 0 0 84 2,-0.0 2,-0.3 56,-0.0 -1,-0.2 0.553 85.7 32.1 -81.1 -9.4 -16.0 17.2 9.1 72 74 A Q S S- 0 0 116 -3,-0.3 2,-1.3 2,-0.1 0, 0.0 -0.929 100.8 -85.2-141.2 165.3 -19.4 17.3 10.8 73 75 A D S S+ 0 0 99 -2,-0.3 2,-0.3 14,-0.1 3,-0.1 -0.616 75.2 125.9 -75.8 96.9 -21.1 15.7 13.8 74 76 A K + 0 0 50 -2,-1.3 14,-0.2 1,-0.3 -21,-0.2 -0.951 64.3 21.7-152.2 130.3 -22.4 12.5 12.2 75 77 A A S S+ 0 0 6 -27,-0.4 13,-2.4 -2,-0.3 2,-0.3 0.969 80.7 175.1 70.4 82.6 -21.6 9.0 13.6 76 78 A V E -DH 48 87B 11 -28,-1.6 -28,-2.6 11,-0.2 2,-0.5 -0.930 28.5-146.4-126.1 151.0 -20.7 9.7 17.2 77 79 A L E +DH 47 86B 0 9,-2.5 9,-1.8 -2,-0.3 2,-0.3 -0.958 32.6 158.1-114.2 125.8 -19.9 7.6 20.2 78 80 A K E +D 46 0B 83 -32,-2.8 -32,-3.2 -2,-0.5 7,-0.1 -0.843 32.1 28.9-139.2 176.3 -21.1 8.9 23.6 79 81 A G S > S+ 0 0 15 5,-0.5 3,-2.0 3,-0.3 -34,-0.3 -0.202 74.7 82.3 69.2-160.6 -21.9 7.8 27.2 80 82 A G T 3 S- 0 0 0 -36,-0.5 -37,-1.6 -37,-0.3 -1,-0.1 -0.435 121.0 -22.6 63.4-131.3 -20.3 4.8 28.9 81 83 A P T 3 S+ 0 0 47 0, 0.0 -1,-0.3 0, 0.0 2,-0.2 0.506 116.7 107.8 -89.1 -4.1 -16.9 5.8 30.3 82 84 A L < - 0 0 6 -3,-2.0 2,-0.6 -39,-0.1 -3,-0.3 -0.510 57.5-153.1 -81.2 141.3 -16.7 8.7 27.8 83 85 A D - 0 0 103 -2,-0.2 2,-0.2 53,-0.1 -1,-0.0 -0.961 67.9 -12.4-111.3 118.6 -17.1 12.4 28.7 84 86 A G S S- 0 0 42 -2,-0.6 -5,-0.5 39,-0.1 2,-0.4 -0.509 102.2 -40.1 92.2-159.8 -18.4 14.4 25.8 85 87 A T - 0 0 48 -2,-0.2 38,-2.5 -7,-0.1 2,-0.4 -0.913 42.4-163.5-116.9 135.9 -18.7 13.4 22.1 86 88 A Y E -HI 77 122B 4 -9,-1.8 -9,-2.5 -2,-0.4 2,-0.4 -0.952 16.1-140.1-116.0 135.4 -16.2 11.3 20.0 87 89 A R E -HI 76 121B 38 34,-2.8 34,-1.8 -2,-0.4 -11,-0.2 -0.822 16.2-118.7-104.4 131.0 -16.5 11.3 16.2 88 90 A L E + I 0 120B 1 -13,-2.4 32,-0.3 -2,-0.4 -14,-0.1 -0.422 37.6 164.1 -63.6 127.7 -16.0 8.3 14.0 89 91 A I E - 0 0 37 30,-3.0 -21,-2.5 1,-0.4 2,-0.3 0.687 59.8 -25.5-115.8 -32.6 -13.0 8.8 11.6 90 92 A Q E -GI 67 119B 34 29,-1.2 29,-3.1 -23,-0.2 -1,-0.4 -0.981 46.7-143.5-172.7 164.3 -12.3 5.2 10.3 91 93 A F E +GI 66 118B 0 -25,-1.6 -25,-2.6 -2,-0.3 2,-0.3 -0.991 22.3 160.9-140.8 146.5 -12.5 1.5 11.0 92 94 A H E - I 0 117B 25 25,-1.6 25,-3.1 -2,-0.3 2,-0.3 -0.880 24.4-124.4-149.9 178.7 -10.2 -1.3 10.2 93 95 A F E - I 0 116B 0 -29,-0.4 2,-0.4 -2,-0.3 -29,-0.2 -0.831 1.5-147.7-131.6 169.8 -9.5 -4.9 11.3 94 96 A H E + I 0 115B 2 21,-1.8 21,-2.1 -2,-0.3 2,-0.3 -0.996 32.1 163.6-135.1 128.6 -6.8 -7.2 12.7 95 97 A W E - I 0 114B 0 -2,-0.4 146,-1.2 19,-0.2 145,-0.8 -0.927 25.7-120.2-145.3 170.3 -6.9 -10.8 11.7 96 98 A G - 0 0 0 17,-1.4 6,-0.1 5,-0.7 3,-0.1 -0.432 25.8-115.5-107.5-177.5 -4.8 -14.0 11.6 97 99 A S S S+ 0 0 44 142,-0.2 2,-0.3 -2,-0.1 5,-0.1 0.543 106.4 33.3 -89.3 -10.9 -3.6 -16.6 9.1 98 100 A L S > S- 0 0 112 3,-0.3 3,-1.7 15,-0.1 -2,-0.2 -0.962 87.7-114.8-141.0 153.6 -5.8 -19.2 10.8 99 101 A D T 3 S+ 0 0 67 -2,-0.3 48,-0.1 1,-0.3 -3,-0.0 0.790 108.7 72.0 -62.1 -26.3 -9.1 -18.9 12.6 100 102 A G T 3 S+ 0 0 60 13,-0.1 2,-0.3 2,-0.1 -1,-0.3 0.554 108.0 24.3 -67.5 -6.7 -7.5 -19.8 15.9 101 103 A Q < + 0 0 55 -3,-1.7 -5,-0.7 12,-0.2 -3,-0.3 -0.964 66.0 99.0-151.7 166.7 -5.8 -16.4 16.1 102 104 A G + 0 0 0 1,-0.5 13,-0.3 -2,-0.3 11,-0.2 0.020 52.8 106.3 144.7 -34.9 -6.1 -12.8 14.9 103 105 A S - 0 0 1 9,-2.0 -1,-0.5 11,-0.3 12,-0.1 -0.335 53.6-149.3 -73.7 160.2 -7.7 -10.6 17.5 104 106 A E S S+ 0 0 1 -10,-0.1 2,-0.1 -3,-0.1 -1,-0.1 0.887 84.1 51.8 -93.0 -56.3 -5.5 -8.1 19.5 105 107 A H S S- 0 0 0 -77,-0.1 7,-0.5 140,-0.1 2,-0.3 -0.505 78.7-156.3 -76.9 152.5 -7.4 -8.1 22.8 106 108 A T E -a 30 0A 8 -77,-1.1 -75,-2.9 -2,-0.1 2,-0.6 -0.903 12.5-133.6-128.5 157.1 -8.1 -11.6 24.2 107 109 A V E > S-aB 31 110A 16 3,-2.0 3,-2.1 -2,-0.3 -75,-0.2 -0.936 89.8 -22.9-116.5 109.5 -10.8 -12.9 26.7 108 110 A D T 3 S- 0 0 68 -77,-1.7 -1,-0.2 -2,-0.6 -76,-0.1 0.934 128.8 -52.7 54.1 45.3 -9.3 -15.0 29.4 109 111 A K T 3 S+ 0 0 159 1,-0.2 2,-0.4 -3,-0.1 -1,-0.3 0.359 106.4 139.9 72.8 -3.2 -6.4 -15.6 27.0 110 112 A K B < -B 107 0A 107 -3,-2.1 -3,-2.0 1,-0.0 2,-0.5 -0.578 42.0-149.7 -76.6 126.9 -8.9 -16.7 24.3 111 113 A K - 0 0 87 -2,-0.4 -5,-0.1 -11,-0.3 2,-0.1 -0.837 7.8-148.9 -97.7 128.1 -7.9 -15.4 20.8 112 114 A Y - 0 0 35 -2,-0.5 -9,-2.0 -7,-0.5 34,-0.2 -0.429 28.8-106.2 -88.3 170.5 -10.7 -14.6 18.3 113 115 A A S S- 0 0 6 32,-1.1 -17,-1.4 -11,-0.2 2,-0.3 0.785 93.1 -17.5 -66.3 -29.3 -10.4 -14.9 14.5 114 116 A A E -IJ 95 145B 1 31,-1.4 31,-2.7 -19,-0.2 2,-0.3 -0.965 58.1-134.0-164.6 174.7 -10.3 -11.2 14.1 115 117 A E E -IJ 94 144B 0 -21,-2.1 -21,-1.8 -2,-0.3 2,-0.4 -0.985 11.4-146.5-147.6 131.9 -11.0 -7.8 15.7 116 118 A L E -IJ 93 143B 0 27,-3.4 27,-2.1 -2,-0.3 2,-0.5 -0.819 11.0-160.5 -99.6 136.2 -12.8 -4.8 14.3 117 119 A H E -IJ 92 142B 2 -25,-3.1 -25,-1.6 -2,-0.4 2,-0.8 -0.950 6.7-168.9-123.8 113.2 -11.7 -1.3 15.4 118 120 A L E -IJ 91 141B 0 23,-2.1 23,-2.5 -2,-0.5 2,-0.4 -0.898 21.8-150.9-100.4 109.7 -14.0 1.7 15.0 119 121 A V E +IJ 90 140B 12 -29,-3.1 -30,-3.0 -2,-0.8 -29,-1.2 -0.715 19.3 174.8 -91.5 130.3 -11.9 4.7 15.7 120 122 A H E -IJ 88 139B 0 19,-1.8 19,-2.4 -2,-0.4 2,-0.4 -0.957 16.7-146.8-131.7 150.5 -13.2 8.0 17.1 121 123 A W E -IJ 87 138B 8 -34,-1.8 -34,-2.8 -2,-0.3 2,-0.5 -0.919 30.8-102.7-119.5 145.4 -11.7 11.3 18.3 122 124 A N E > -I 86 0B 2 15,-3.4 3,-2.2 -2,-0.4 -36,-0.2 -0.496 26.7-147.6 -66.7 113.6 -12.8 13.6 21.1 123 125 A T G > S+ 0 0 39 -38,-2.5 3,-1.4 -2,-0.5 -1,-0.2 0.662 90.2 73.7 -58.6 -19.1 -14.5 16.6 19.4 124 127 A K G 3 S+ 0 0 118 -39,-0.4 -1,-0.3 1,-0.3 -2,-0.1 0.652 91.2 60.9 -72.8 -7.9 -13.4 19.0 22.1 125 128 A Y G < S- 0 0 49 -3,-2.2 2,-1.9 12,-0.1 -1,-0.3 0.187 105.4-124.0-102.3 16.9 -9.9 18.8 20.6 126 129 A G S < S- 0 0 58 -3,-1.4 2,-0.3 4,-0.1 -3,-0.1 -0.211 73.9 -7.8 77.3 -52.5 -10.8 20.1 17.1 127 130 A D S > S- 0 0 81 -2,-1.9 4,-2.3 -5,-0.2 5,-0.1 -0.959 81.7 -79.8-163.1 179.8 -9.5 17.2 15.1 128 131 A F H > S+ 0 0 69 -2,-0.3 4,-2.3 1,-0.2 5,-0.2 0.944 119.4 56.2 -56.3 -53.4 -7.6 13.9 15.1 129 132 A G H 4 S+ 0 0 35 1,-0.2 -1,-0.2 2,-0.2 3,-0.1 0.884 113.6 38.9 -45.9 -52.3 -4.1 15.5 15.1 130 133 A K H >4 S+ 0 0 110 -5,-0.2 3,-1.5 1,-0.2 -1,-0.2 0.860 111.5 60.8 -68.5 -36.4 -4.8 17.5 18.2 131 134 A A H >< S+ 0 0 0 -4,-2.3 3,-1.9 1,-0.3 6,-0.3 0.876 95.1 60.7 -59.5 -39.8 -6.7 14.7 19.8 132 135 A V T 3< S+ 0 0 25 -4,-2.3 -1,-0.3 1,-0.3 -2,-0.1 0.308 95.1 64.3 -74.7 13.2 -3.7 12.3 19.7 133 136 A Q T < S+ 0 0 126 -3,-1.5 -1,-0.3 -5,-0.2 -2,-0.2 0.205 94.9 78.5-113.7 9.5 -1.8 14.8 22.0 134 137 A Q S X S- 0 0 54 -3,-1.9 3,-1.4 1,-0.1 4,-0.3 -0.907 78.5-131.8-123.6 147.4 -4.3 14.2 24.8 135 138 A P T 3 S+ 0 0 84 0, 0.0 3,-0.1 0, 0.0 -1,-0.1 0.714 115.1 31.8 -67.4 -18.0 -4.8 11.3 27.3 136 139 A D T 3 S+ 0 0 41 -5,-0.1 -53,-0.1 1,-0.1 68,-0.1 -0.081 85.2 114.2-127.3 32.5 -8.5 11.3 26.4 137 140 A G S < S+ 0 0 0 -3,-1.4 -15,-3.4 -6,-0.3 2,-0.3 0.781 73.1 42.9 -75.5 -25.9 -8.3 12.2 22.8 138 141 A L E -Jk 121 204B 0 65,-2.7 67,-2.2 -4,-0.3 2,-0.3 -0.844 50.6-170.3-127.4 160.7 -9.5 8.9 21.4 139 142 A A E -Jk 120 205B 0 -19,-2.4 -19,-1.8 -2,-0.3 2,-0.5 -0.946 10.7-167.6-145.8 118.8 -12.1 6.2 21.8 140 143 A V E -Jk 119 206B 5 65,-1.3 67,-2.3 -2,-0.3 2,-0.8 -0.948 11.6-149.4-114.3 125.7 -11.9 2.9 19.9 141 144 A L E -Jk 118 207B 0 -23,-2.5 -23,-2.1 -2,-0.5 2,-0.4 -0.838 19.2-159.1 -93.1 111.6 -14.9 0.5 19.9 142 145 A G E -Jk 117 208B 0 65,-3.0 67,-2.8 -2,-0.8 2,-0.4 -0.788 11.9-177.8 -98.2 135.0 -13.5 -3.0 19.6 143 146 A I E -J 116 0B 0 -27,-2.1 -27,-3.4 -2,-0.4 2,-0.2 -0.995 20.4-132.8-134.0 126.4 -15.6 -5.9 18.3 144 147 A F E -J 115 0B 0 65,-0.4 69,-2.9 -2,-0.4 2,-0.4 -0.492 13.2-147.1 -78.9 145.4 -14.5 -9.5 18.1 145 148 A L E -Jl 114 213B 2 -31,-2.7 -31,-1.4 67,-0.2 -32,-1.1 -0.935 14.6-176.4-114.6 134.4 -15.0 -11.6 15.0 146 149 A K E - l 0 214B 97 67,-2.2 69,-2.7 -2,-0.4 2,-0.5 -0.939 31.2-109.2-126.0 150.4 -15.6 -15.4 15.1 147 150 A V E S+ l 0 215B 43 -2,-0.3 69,-0.2 67,-0.2 2,-0.2 -0.696 74.0 86.7 -85.7 126.3 -16.0 -17.8 12.2 148 151 A G S S+ 0 0 45 67,-3.0 69,-0.5 -2,-0.5 2,-0.1 -0.587 79.4 13.8-173.7-120.3 -19.5 -19.1 11.7 149 152 A S S S- 0 0 87 -2,-0.2 -1,-0.3 67,-0.1 0, 0.0 -0.474 87.8 -94.3 -77.2 151.7 -22.4 -17.8 9.7 150 153 A A - 0 0 52 65,-0.2 65,-0.2 -2,-0.1 64,-0.1 -0.222 25.2-129.0 -65.3 154.6 -21.8 -14.9 7.4 151 154 A K >> - 0 0 39 1,-0.2 3,-2.2 62,-0.1 4,-0.7 -0.905 16.5-159.4-106.1 102.1 -22.2 -11.2 8.4 152 155 A P G >4 S+ 0 0 111 0, 0.0 3,-1.3 0, 0.0 4,-0.4 0.882 88.0 57.0 -47.7 -47.6 -24.4 -9.7 5.7 153 156 A G G 34 S+ 0 0 27 27,-0.4 27,-0.2 1,-0.2 4,-0.1 0.485 103.2 54.8 -67.4 -3.5 -23.3 -6.1 6.5 154 157 A L G X> S+ 0 0 1 -3,-2.2 4,-2.0 2,-0.1 3,-0.7 0.565 84.2 85.3-103.5 -13.7 -19.7 -6.9 5.9 155 158 A Q H S+ 0 0 151 -4,-0.4 4,-0.6 1,-0.2 -1,-0.2 0.861 109.9 47.6 -57.8 -32.2 -19.8 -5.0 0.6 157 160 A V H X> S+ 0 0 0 -3,-0.7 3,-0.9 2,-0.2 4,-0.8 0.924 110.2 52.3 -72.3 -44.1 -16.4 -4.6 2.3 158 161 A V H >< S+ 0 0 3 -4,-2.0 3,-1.0 1,-0.2 4,-0.3 0.925 107.6 51.3 -56.7 -48.4 -15.4 -8.1 1.3 159 162 A D H 3< S+ 0 0 89 -4,-2.9 3,-0.3 1,-0.2 -1,-0.2 0.626 106.2 54.4 -67.7 -15.1 -16.2 -7.6 -2.4 160 163 A V H X< S+ 0 0 22 -3,-0.9 3,-1.3 -4,-0.6 4,-0.4 0.613 84.0 84.7 -94.1 -12.4 -14.2 -4.4 -2.7 161 164 A L G X< S+ 0 0 7 -3,-1.0 3,-1.1 -4,-0.8 -1,-0.2 0.756 78.0 69.2 -59.7 -25.6 -11.0 -5.9 -1.3 162 165 A D G > S+ 0 0 133 -4,-0.3 3,-0.8 -3,-0.3 -1,-0.3 0.884 97.2 51.9 -60.2 -38.2 -10.2 -7.1 -4.9 163 166 A S G < S+ 0 0 47 -3,-1.3 -1,-0.2 1,-0.2 -2,-0.2 0.553 114.6 41.3 -77.4 -8.4 -9.6 -3.5 -6.0 164 167 A I G < + 0 0 0 -3,-1.1 -1,-0.2 -4,-0.4 63,-0.2 -0.198 68.1 137.8-133.1 45.0 -7.2 -2.8 -3.1 165 168 A K < + 0 0 93 -3,-0.8 62,-3.1 61,-0.1 2,-0.2 0.872 63.7 50.4 -56.9 -42.7 -5.0 -5.9 -3.0 166 169 A T S > S- 0 0 13 60,-0.2 3,-1.8 1,-0.1 -107,-0.3 -0.640 97.2 -81.1-107.6 160.4 -1.7 -4.1 -2.6 167 170 A K B 3 S+o 230 0C 89 62,-2.5 64,-0.5 1,-0.2 -107,-0.2 -0.233 112.4 22.3 -53.9 130.2 -0.2 -1.4 -0.4 168 171 A G T 3 S+ 0 0 57 -109,-3.1 -1,-0.2 1,-0.3 2,-0.1 0.020 90.6 120.8 101.6 -28.0 -1.2 2.1 -1.6 169 172 A K < + 0 0 83 -3,-1.8 -110,-2.5 -110,-0.1 -1,-0.3 -0.421 34.8 175.7 -73.7 146.2 -4.3 1.2 -3.5 170 173 A S E -F 58 0B 51 -112,-0.2 2,-0.3 -7,-0.1 -112,-0.2 -0.969 10.8-161.4-145.3 155.4 -7.6 2.8 -2.5 171 174 A A E -F 57 0B 23 -114,-2.4 -114,-2.4 -2,-0.3 -7,-0.0 -0.996 33.9 -93.1-142.7 145.5 -11.1 2.7 -4.0 172 175 A D E +F 56 0B 132 -2,-0.3 -116,-0.3 -116,-0.2 -117,-0.1 -0.226 42.7 174.4 -53.1 142.3 -14.2 4.8 -3.6 173 176 A F + 0 0 21 -118,-2.0 3,-0.4 -106,-0.1 -117,-0.2 -0.367 10.4 158.8-155.6 67.3 -16.4 3.5 -0.9 174 177 A T + 0 0 70 1,-0.2 -119,-0.2 -119,-0.2 -121,-0.1 -0.419 55.6 29.3 -89.8 167.6 -19.4 5.7 -0.2 175 178 A N S S+ 0 0 143 -121,-0.6 2,-0.6 1,-0.2 -1,-0.2 0.685 72.7 152.7 58.2 25.4 -22.7 4.8 1.5 176 179 A F - 0 0 12 -3,-0.4 -122,-0.3 -20,-0.0 -1,-0.2 -0.760 36.6-145.7 -86.9 126.1 -21.3 2.0 3.7 177 180 A D > - 0 0 64 -2,-0.6 3,-1.9 1,-0.1 -127,-0.1 -0.777 9.7-166.1 -94.4 104.5 -23.4 1.7 6.9 178 181 A P G > S+ 0 0 0 0, 0.0 3,-1.5 0, 0.0 4,-0.2 0.641 79.3 81.3 -63.3 -12.1 -21.2 0.6 9.8 179 182 A R G > S+ 0 0 127 1,-0.3 3,-1.1 -130,-0.2 -26,-0.1 0.744 78.6 68.9 -65.5 -21.5 -24.3 -0.3 11.8 180 183 A G G < S+ 0 0 31 -3,-1.9 -27,-0.4 1,-0.2 -1,-0.3 0.284 93.5 58.6 -80.7 13.0 -24.4 -3.6 9.9 181 184 A L G < S+ 0 0 0 -3,-1.5 -1,-0.2 -28,-0.1 -2,-0.2 0.402 83.0 101.6-118.2 -1.7 -21.2 -4.7 11.8 182 185 A L < - 0 0 36 -3,-1.1 4,-0.1 -4,-0.2 -39,-0.0 -0.671 66.5-128.9 -93.0 137.4 -22.5 -4.4 15.4 183 186 A P - 0 0 13 0, 0.0 30,-0.1 0, 0.0 -1,-0.1 -0.034 32.5-103.6 -67.0-178.2 -23.6 -7.3 17.5 184 187 A E S S+ 0 0 190 2,-0.0 2,-0.2 0, 0.0 29,-0.0 0.956 101.4 57.4 -72.6 -51.9 -27.0 -7.2 19.3 185 188 A S - 0 0 34 1,-0.1 26,-0.1 2,-0.0 24,-0.0 -0.494 60.3-160.2 -84.1 148.9 -25.7 -6.4 22.7 186 189 A L + 0 0 63 -2,-0.2 -141,-0.1 23,-0.1 -1,-0.1 0.109 42.7 139.1-110.8 18.0 -23.6 -3.5 23.7 187 190 A D + 0 0 60 22,-0.1 23,-2.2 68,-0.0 24,-0.4 -0.376 33.4 170.8 -59.9 145.5 -22.2 -5.0 26.9 188 191 A Y E -M 209 0B 5 21,-0.3 68,-2.1 22,-0.1 2,-0.4 -0.989 39.6-128.7-157.6 164.2 -18.5 -4.1 27.1 189 192 A W E -MN 208 255B 13 19,-2.8 19,-3.0 -2,-0.3 2,-0.3 -0.866 31.9-167.0-110.9 148.5 -15.3 -4.0 29.0 190 193 A T E +MN 207 254B 9 64,-2.1 64,-2.4 -2,-0.4 17,-0.2 -1.000 16.9 151.1-143.2 143.8 -13.4 -0.7 29.2 191 194 A Y E -M 206 0B 3 15,-1.3 15,-2.4 -2,-0.3 2,-0.4 -0.976 46.9 -93.5-163.3 156.4 -10.0 0.5 30.2 192 195 A P E +M 205 0B 56 0, 0.0 13,-0.2 0, 0.0 2,-0.2 -0.638 63.0 130.1 -79.2 129.5 -7.5 3.3 29.4 193 196 A G E -M 204 0B 0 11,-3.6 11,-1.6 -2,-0.4 2,-0.2 -0.565 42.4 -92.6-149.2-146.6 -4.9 2.3 26.7 194 197 A S - 0 0 0 8,-0.2 8,-0.2 9,-0.2 7,-0.1 -0.797 43.8 -73.6-139.6 178.5 -3.1 3.1 23.5 195 198 A L - 0 0 29 6,-1.7 -168,-0.5 -2,-0.2 9,-0.0 -0.495 41.4-137.4 -70.5 148.5 -3.1 2.7 19.7 196 199 A T S S+ 0 0 7 -2,-0.1 -1,-0.1 -170,-0.1 -170,-0.0 0.388 83.3 52.0 -93.5 4.6 -2.1 -0.9 18.9 197 200 A T S > S- 0 0 37 4,-0.1 3,-2.9 46,-0.0 4,-0.3 -0.912 102.9 -44.9-131.7 158.5 0.3 0.1 16.1 198 201 A P T 3 S+ 0 0 8 0, 0.0 -2,-0.1 0, 0.0 -1,-0.0 -0.314 125.1 42.0 -56.3 150.7 3.1 2.7 16.0 199 202 A P T 3 S- 0 0 59 0, 0.0 -179,-0.1 0, 0.0 -3,-0.0 -0.981 85.2-165.4 -71.0 4.9 3.2 5.5 17.1 200 203 A L < - 0 0 0 -3,-2.9 2,-0.1 1,-0.2 -173,-0.1 0.831 15.4-171.7 51.3 38.6 1.4 3.5 19.8 201 204 A L - 0 0 53 -4,-0.3 2,-1.8 -7,-0.1 -6,-1.7 -0.377 25.9-131.1 -65.5 133.6 0.2 6.8 21.5 202 205 A E S S+ 0 0 41 -8,-0.2 -8,-0.2 1,-0.2 -1,-0.1 -0.449 75.1 108.7 -86.1 67.8 -1.5 6.3 24.9 203 206 A C + 0 0 8 -2,-1.8 -65,-2.7 -67,-0.1 2,-0.4 0.152 49.6 112.5-124.9 15.0 -4.5 8.5 24.1 204 207 A V E -kM 138 193B 0 -11,-1.6 -11,-3.6 -3,-0.3 2,-0.8 -0.786 48.3-162.5-107.4 133.5 -7.2 5.8 23.9 205 208 A T E -kM 139 192B 25 -67,-2.2 -65,-1.3 -2,-0.4 2,-0.3 -0.931 31.3-147.3-100.2 111.9 -10.2 4.9 26.0 206 209 A W E -kM 140 191B 4 -15,-2.4 -15,-1.3 -2,-0.8 2,-0.5 -0.673 19.2-174.1 -86.7 138.2 -10.9 1.4 24.8 207 210 A I E -kM 141 190B 0 -67,-2.3 -65,-3.0 -2,-0.3 2,-0.6 -0.961 9.3-173.7-130.0 105.9 -14.5 0.0 24.7 208 211 A V E -kM 142 189B 0 -19,-3.0 -19,-2.8 -2,-0.5 -65,-0.2 -0.928 19.4-132.4-109.8 118.7 -14.5 -3.7 23.9 209 212 A L E - M 0 188B 0 -67,-2.8 -65,-0.4 -2,-0.6 -21,-0.3 -0.422 2.9-147.2 -71.3 139.2 -17.8 -5.4 23.3 210 213 A K S S+ 0 0 92 -23,-2.2 -1,-0.1 -2,-0.1 -22,-0.1 0.939 83.0 67.7 -69.6 -50.5 -18.5 -8.7 25.0 211 214 A E S S- 0 0 70 -24,-0.4 -67,-0.2 -26,-0.1 2,-0.1 -0.603 77.2-151.4 -75.7 123.7 -20.7 -10.2 22.2 212 215 A P - 0 0 29 0, 0.0 2,-0.3 0, 0.0 -67,-0.2 -0.490 12.5-119.2 -90.8 164.3 -18.7 -10.9 19.1 213 216 A I E -l 145 0B 3 -69,-2.9 -67,-2.2 -2,-0.1 2,-0.4 -0.737 22.9-125.5 -99.6 155.1 -20.1 -10.9 15.5 214 217 A S E +l 146 0B 36 -2,-0.3 2,-0.3 -69,-0.2 -67,-0.2 -0.850 27.6 179.2-102.3 133.9 -20.0 -14.0 13.3 215 218 A V E -l 147 0B 2 -69,-2.7 -67,-3.0 -2,-0.4 -65,-0.2 -0.892 31.0-103.8-126.1 158.2 -18.4 -13.9 9.9 216 219 A S > - 0 0 10 -2,-0.3 4,-2.1 -69,-0.2 5,-0.3 -0.443 22.3-118.3 -84.3 158.4 -18.1 -16.7 7.4 217 220 A S H > S+ 0 0 42 -69,-0.5 4,-2.0 1,-0.2 5,-0.1 0.888 118.1 55.5 -58.9 -38.0 -15.0 -18.7 6.6 218 221 A E H > S+ 0 0 126 1,-0.2 4,-1.3 2,-0.2 -1,-0.2 0.896 106.2 50.4 -61.8 -42.9 -15.3 -17.4 3.1 219 222 A Q H > S+ 0 0 2 1,-0.2 4,-1.1 2,-0.2 3,-0.4 0.936 113.7 41.6 -62.9 -50.0 -15.4 -13.7 4.2 220 223 A V H X S+ 0 0 3 -4,-2.1 4,-1.6 1,-0.2 -1,-0.2 0.834 107.2 64.6 -69.1 -29.2 -12.3 -13.9 6.5 221 224 A L H < S+ 0 0 77 -4,-2.0 -1,-0.2 -5,-0.3 4,-0.2 0.887 100.5 51.3 -60.6 -35.7 -10.5 -15.9 3.8 222 225 A K H >< S+ 0 0 77 -4,-1.3 3,-1.6 -3,-0.4 4,-0.5 0.866 101.6 59.3 -70.9 -33.6 -10.8 -12.9 1.5 223 226 A F H >< S+ 0 0 2 -4,-1.1 3,-1.3 1,-0.3 -1,-0.2 0.905 104.0 54.9 -55.5 -41.0 -9.2 -10.7 4.2 224 227 A R T 3< S+ 0 0 28 -4,-1.6 -1,-0.3 1,-0.2 -2,-0.2 0.515 94.3 66.9 -73.0 -6.9 -6.2 -13.1 3.9 225 228 A K T < S+ 0 0 145 -3,-1.6 -1,-0.2 -4,-0.2 -2,-0.2 0.581 80.6 101.8 -89.1 -11.4 -5.9 -12.6 0.2 226 229 A L < - 0 0 3 -3,-1.3 12,-3.1 -4,-0.5 2,-0.3 -0.190 69.3-125.8 -67.1 164.4 -4.8 -9.0 0.6 227 230 A N B -P 237 0D 5 -62,-3.1 -166,-0.2 10,-0.3 10,-0.2 -0.867 17.8-159.0-118.1 150.8 -1.1 -8.1 0.4 228 231 A F S S+ 0 0 36 8,-2.5 -1,-0.1 -2,-0.3 9,-0.1 0.827 81.5 73.9 -86.6 -40.7 1.4 -6.2 2.7 229 232 A N S S- 0 0 5 7,-0.5 -62,-2.5 5,-0.2 2,-0.2 -0.094 87.5-108.3 -67.9 167.7 3.6 -5.5 -0.3 230 233 A G B > -o 167 0C 3 -64,-0.2 3,-1.7 1,-0.2 -1,-0.1 -0.476 51.8 -66.5 -93.6 168.8 2.9 -3.0 -3.1 231 234 A E T 3 S+ 0 0 157 -64,-0.5 -1,-0.2 1,-0.3 4,-0.0 -0.234 122.2 21.0 -55.3 137.8 2.0 -3.7 -6.7 232 235 A G T 3 S+ 0 0 86 1,-0.3 -1,-0.3 -3,-0.1 3,-0.1 0.497 101.5 115.0 81.0 3.9 4.7 -5.5 -8.7 233 236 A E S < S- 0 0 90 -3,-1.7 -1,-0.3 1,-0.1 3,-0.1 -0.674 81.3 -80.3-105.1 159.3 6.4 -6.7 -5.5 234 237 A P - 0 0 109 0, 0.0 2,-0.3 0, 0.0 -5,-0.2 -0.304 62.4-100.5 -55.0 139.1 6.9 -10.3 -4.2 235 238 A E + 0 0 111 -7,-0.1 2,-0.4 -8,-0.1 -8,-0.1 -0.466 41.5 176.6 -73.8 131.2 3.7 -11.4 -2.6 236 239 A E - 0 0 105 -2,-0.3 -8,-2.5 -3,-0.1 -7,-0.5 -0.957 31.9-128.3-129.7 105.3 3.4 -11.3 1.2 237 240 A L B -P 227 0D 86 -2,-0.4 2,-1.4 -10,-0.2 -10,-0.3 -0.293 19.1-119.4 -59.0 138.3 -0.1 -12.2 2.3 238 241 A M + 0 0 0 -12,-3.1 2,-0.3 -15,-0.2 -12,-0.3 -0.667 64.1 131.7 -82.1 92.2 -1.7 -9.7 4.7 239 242 A V + 0 0 30 -2,-1.4 -143,-0.2 1,-0.1 -142,-0.2 -0.970 51.5 22.9-141.9 156.0 -2.2 -12.0 7.7 240 243 A D + 0 0 41 -145,-0.8 2,-0.6 -2,-0.3 -144,-0.2 0.913 63.0 158.1 54.3 48.5 -1.5 -11.9 11.5 241 244 A N + 0 0 0 -146,-1.2 2,-0.3 -3,-0.1 -1,-0.2 -0.342 36.4 114.3 -95.9 50.7 -1.4 -8.1 11.5 242 245 A W - 0 0 39 -2,-0.6 -139,-0.1 -148,-0.1 -138,-0.1 -0.924 62.8-131.8-123.7 148.1 -2.2 -8.1 15.2 243 246 A R - 0 0 4 -2,-0.3 3,-0.1 -141,-0.1 -2,-0.1 -0.797 31.1-115.5 -97.7 138.2 -0.2 -7.0 18.3 244 247 A P - 0 0 46 0, 0.0 2,-0.1 0, 0.0 -1,-0.1 -0.188 44.6 -76.7 -67.0 164.0 -0.0 -9.4 21.3 245 248 A A - 0 0 47 -216,-0.1 -216,-0.3 1,-0.1 -218,-0.1 -0.385 51.0-146.7 -65.1 138.0 -1.5 -8.6 24.7 246 249 A Q - 0 0 38 -218,-3.5 -216,-0.4 -220,-0.1 -1,-0.1 -0.587 32.3 -71.8-102.6 164.6 0.6 -6.1 26.7 247 250 A P - 0 0 73 0, 0.0 -221,-0.4 0, 0.0 -1,-0.1 -0.307 33.5-145.3 -59.7 133.8 1.2 -5.9 30.5 248 251 A L + 0 0 66 1,-0.1 -2,-0.0 -223,-0.1 -219,-0.0 0.864 36.5 166.0 -66.0 -38.9 -1.8 -4.6 32.4 249 252 A K - 0 0 91 1,-0.2 2,-1.7 -224,-0.1 -1,-0.1 -0.224 65.3 -5.8 54.9-138.0 0.3 -2.7 34.9 250 253 A N S S+ 0 0 159 -226,-0.3 2,-0.3 2,-0.0 -1,-0.2 -0.473 107.1 107.1 -89.9 73.6 -1.6 -0.2 37.0 251 254 A R - 0 0 22 -2,-1.7 2,-0.4 -60,-0.0 -60,-0.0 -0.980 51.9-150.2-143.1 152.1 -5.0 -0.4 35.3 252 255 A Q - 0 0 144 -2,-0.3 2,-0.6 -62,-0.0 -216,-0.1 -0.990 14.1-140.1-125.8 133.2 -8.4 -1.9 36.1 253 256 A I - 0 0 12 -2,-0.4 -216,-1.6 -221,-0.1 2,-0.3 -0.831 22.3-155.4 -93.2 125.1 -10.8 -3.2 33.4 254 257 A K E -cN 37 190B 46 -64,-2.4 -64,-2.1 -2,-0.6 2,-0.4 -0.758 3.5-140.6-102.3 148.8 -14.3 -2.2 34.3 255 258 A A E -cN 38 189B 6 -218,-2.9 -216,-2.8 -2,-0.3 -66,-0.2 -0.868 7.5-152.8-110.1 143.2 -17.5 -4.0 33.1 256 259 A S S S+ 0 0 30 -68,-2.1 2,-0.2 -2,-0.4 -67,-0.1 0.484 82.6 23.8 -88.3 -4.8 -20.7 -2.3 32.0 257 260 A F 0 0 35 -69,-0.3 -2,-0.1 1,-0.1 -218,-0.1 -0.513 360.0 360.0-135.8-157.8 -22.7 -5.4 33.0 258 261 A K 0 0 231 -2,-0.2 -1,-0.1 -220,-0.1 -2,-0.0 0.069 360.0 360.0-166.2 360.0 -22.7 -8.5 35.3