==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 02-MAY-05 1ZK1 . COMPND 2 MOLECULE: R-SPECIFIC ALCOHOL DEHYDROGENASE; . SOURCE 2 ORGANISM_SCIENTIFIC: LACTOBACILLUS BREVIS; . AUTHOR N.H.SCHLIEBEN,K.NIEFIND,J.MULLER,B.RIEBEL,W.HUMMEL,D.SCHOMBU . 251 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 11740.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 188 74.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 36 14.3 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 12 4.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 31 12.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 94 37.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 4 1.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 1 0 0 0 0 0 2 2 0 1 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 2 0 1 3 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A S 0 0 105 0, 0.0 28,-0.2 0, 0.0 27,-0.1 0.000 360.0 360.0 360.0 139.9 0.1 34.4 3.7 2 2 A N > + 0 0 102 26,-0.4 3,-1.4 1,-0.1 27,-0.1 0.437 360.0 128.0 69.8 9.4 -3.4 34.0 5.1 3 3 A R T 3 S+ 0 0 83 1,-0.3 229,-0.4 25,-0.1 230,-0.2 0.708 80.7 35.8 -75.2 -15.3 -3.7 30.3 4.3 4 4 A L T > S+ 0 0 1 25,-2.7 3,-2.1 22,-0.2 -1,-0.3 -0.117 82.5 165.4-123.0 30.2 -4.7 29.5 8.0 5 5 A D T < S+ 0 0 94 -3,-1.4 26,-0.1 1,-0.3 25,-0.1 -0.198 70.5 4.8 -59.2 133.7 -6.7 32.6 8.8 6 6 A G T 3 S+ 0 0 73 24,-0.6 -1,-0.3 1,-0.2 25,-0.1 0.264 96.5 135.9 77.4 -8.1 -8.8 32.2 11.9 7 7 A K < - 0 0 10 -3,-2.1 25,-2.4 19,-0.1 2,-0.4 -0.376 40.8-157.7 -74.9 152.5 -7.3 28.7 12.7 8 8 A V E -a 32 0A 8 23,-0.2 76,-2.4 74,-0.1 77,-2.0 -0.991 19.7-170.0-132.1 112.8 -6.3 27.8 16.3 9 9 A A E -ab 33 85A 1 23,-3.1 25,-2.8 -2,-0.4 2,-0.5 -0.898 22.3-156.9-116.5 140.1 -3.7 25.0 16.4 10 10 A I E -ab 34 86A 0 75,-2.5 77,-3.0 -2,-0.4 2,-0.5 -0.942 14.7-171.9-101.1 129.7 -2.2 22.8 19.0 11 11 A I E > -ab 35 87A 0 23,-2.7 25,-1.8 -2,-0.5 3,-0.9 -0.941 13.1-146.9-124.2 111.7 1.2 21.3 18.1 12 12 A T T 3 S+ 0 0 2 75,-2.5 77,-0.3 -2,-0.5 25,-0.1 -0.504 87.4 14.5 -79.2 143.0 2.6 18.7 20.4 13 13 A G T > S+ 0 0 14 48,-0.3 3,-0.5 -2,-0.2 6,-0.4 0.901 85.4 150.4 54.8 41.6 6.4 18.7 20.6 14 14 A G T < + 0 0 0 22,-1.1 9,-0.2 -3,-0.9 23,-0.1 0.238 45.6 78.7 -84.4 11.0 6.3 22.1 18.9 15 15 A T T 3 S+ 0 0 4 21,-0.6 2,-0.3 1,-0.1 -1,-0.2 0.572 93.3 36.1-101.2 -10.8 9.4 23.5 20.4 16 16 A L S X> S- 0 0 91 -3,-0.5 4,-1.5 176,-0.0 3,-0.8 -0.954 104.5 -29.9-139.9 154.1 12.1 21.8 18.3 17 17 A G H 3> S+ 0 0 18 -2,-0.3 4,-2.0 1,-0.2 5,-0.2 -0.042 124.0 6.9 50.1-126.8 12.9 20.7 14.8 18 18 A I H 3> S+ 0 0 36 1,-0.2 4,-2.6 2,-0.2 -1,-0.2 0.925 133.5 51.2 -57.7 -47.4 9.8 19.6 12.7 19 19 A G H <> S+ 0 0 0 -3,-0.8 4,-2.3 -6,-0.4 -2,-0.2 0.885 110.0 49.5 -58.5 -42.2 7.3 20.7 15.4 20 20 A L H X S+ 0 0 45 -4,-1.5 4,-2.4 -7,-0.2 -1,-0.2 0.874 111.1 49.3 -66.2 -41.0 8.9 24.2 15.6 21 21 A A H X S+ 0 0 10 -4,-2.0 4,-2.5 2,-0.2 5,-0.3 0.888 109.2 52.1 -64.3 -41.7 8.9 24.7 11.9 22 22 A I H X S+ 0 0 0 -4,-2.6 4,-2.6 2,-0.2 -2,-0.2 0.956 112.8 46.0 -58.1 -46.4 5.3 23.6 11.7 23 23 A A H X S+ 0 0 0 -4,-2.3 4,-2.3 1,-0.2 5,-0.2 0.920 111.9 51.8 -61.6 -41.8 4.5 26.3 14.5 24 24 A T H X S+ 0 0 50 -4,-2.4 4,-2.3 1,-0.2 -1,-0.2 0.935 114.3 40.7 -62.1 -49.0 6.6 28.9 12.7 25 25 A K H X S+ 0 0 23 -4,-2.5 4,-1.9 1,-0.2 -1,-0.2 0.870 111.8 57.2 -72.1 -32.7 4.8 28.5 9.3 26 26 A F H <>S+ 0 0 1 -4,-2.6 5,-2.5 -5,-0.3 -1,-0.2 0.928 109.4 44.5 -60.1 -48.6 1.5 28.2 11.0 27 27 A V H ><5S+ 0 0 19 -4,-2.3 3,-2.0 1,-0.2 -2,-0.2 0.924 109.6 56.4 -59.3 -46.2 1.9 31.6 12.7 28 28 A E H 3<5S+ 0 0 113 -4,-2.3 -26,-0.4 1,-0.3 -1,-0.2 0.844 107.2 51.0 -57.6 -30.7 3.2 33.0 9.4 29 29 A E T 3<5S- 0 0 15 -4,-1.9 -25,-2.7 -28,-0.2 -1,-0.3 0.290 128.1 -93.7 -89.6 6.4 -0.1 31.9 7.7 30 30 A G T < 5S+ 0 0 28 -3,-2.0 -24,-0.6 1,-0.3 -3,-0.2 0.407 78.6 135.7 99.6 2.6 -2.4 33.4 10.3 31 31 A A < - 0 0 3 -5,-2.5 2,-0.4 -6,-0.2 -1,-0.3 -0.453 51.7-131.0 -81.6 149.0 -2.9 30.6 12.8 32 32 A K E -a 8 0A 70 -25,-2.4 -23,-3.1 -28,-0.1 2,-0.4 -0.821 34.5-156.9 -90.6 145.0 -2.8 31.0 16.6 33 33 A V E -ac 9 56A 0 22,-2.3 24,-2.3 -2,-0.4 2,-0.5 -0.983 26.5-167.8-137.0 132.9 -0.6 28.3 18.0 34 34 A M E -ac 10 57A 4 -25,-2.8 -23,-2.7 -2,-0.4 2,-0.3 -0.980 20.8-165.6-109.8 119.8 -0.1 26.4 21.3 35 35 A I E -ac 11 58A 0 22,-2.8 24,-2.4 -2,-0.5 2,-0.3 -0.799 4.5-158.4-101.8 149.3 3.1 24.4 21.3 36 36 A T E + c 0 59A 2 -25,-1.8 -22,-1.1 -2,-0.3 -21,-0.6 -0.861 19.3 159.8-126.6 161.2 3.9 21.7 23.9 37 37 A D E - c 0 60A 28 22,-0.7 24,-2.0 -2,-0.3 25,-0.1 -0.913 45.4-120.2-168.8 151.6 6.9 19.9 25.3 38 38 A R S S+ 0 0 133 -2,-0.3 2,-0.5 22,-0.2 24,-0.2 0.747 99.8 67.6 -65.6 -25.9 7.5 18.0 28.5 39 39 A H >> - 0 0 74 22,-0.2 4,-1.7 1,-0.1 3,-0.6 -0.884 63.9-162.5-106.0 121.3 10.3 20.5 29.4 40 40 A S H 3> S+ 0 0 41 -2,-0.5 4,-1.9 1,-0.2 5,-0.3 0.817 85.5 66.8 -72.4 -27.1 9.6 24.1 30.2 41 41 A D H 3> S+ 0 0 101 1,-0.2 4,-0.6 2,-0.2 -1,-0.2 0.858 108.7 38.8 -64.5 -31.5 13.0 25.4 29.7 42 42 A V H <> S+ 0 0 35 -3,-0.6 4,-2.2 2,-0.1 -1,-0.2 0.930 113.9 53.0 -80.6 -52.0 12.8 24.7 25.9 43 43 A G H X S+ 0 0 0 -4,-1.7 4,-2.2 1,-0.2 5,-0.2 0.838 103.7 54.0 -60.0 -41.9 9.1 25.7 25.3 44 44 A E H X S+ 0 0 131 -4,-1.9 4,-1.6 1,-0.2 -1,-0.2 0.965 114.0 41.4 -58.7 -48.6 9.2 29.2 26.8 45 45 A K H X S+ 0 0 170 -4,-0.6 4,-2.0 -5,-0.3 -1,-0.2 0.885 111.7 57.3 -63.6 -43.2 12.2 30.3 24.6 46 46 A A H X S+ 0 0 9 -4,-2.2 4,-1.1 2,-0.2 -2,-0.2 0.940 104.8 49.3 -58.3 -51.5 10.8 28.5 21.5 47 47 A A H >X S+ 0 0 9 -4,-2.2 4,-2.2 1,-0.2 3,-1.1 0.948 111.6 48.6 -54.2 -49.5 7.4 30.4 21.5 48 48 A K H 3< S+ 0 0 170 -4,-1.6 -1,-0.2 1,-0.3 -2,-0.2 0.879 104.4 60.5 -62.5 -34.4 9.1 33.8 21.9 49 49 A S H 3< S+ 0 0 85 -4,-2.0 -1,-0.3 1,-0.2 -2,-0.2 0.799 112.5 39.5 -63.0 -27.1 11.5 32.9 19.1 50 50 A V H << S- 0 0 29 -3,-1.1 2,-0.3 -4,-1.1 -2,-0.2 0.807 124.8 -54.1 -90.5 -39.6 8.5 32.5 16.8 51 51 A G < - 0 0 15 -4,-2.2 -1,-0.3 -5,-0.2 -27,-0.0 -0.975 64.3 -51.5-177.9-168.0 6.2 35.3 17.8 52 52 A T >> - 0 0 72 -2,-0.3 4,-2.6 -3,-0.1 3,-2.3 -0.436 55.1-100.5 -89.6 165.3 4.3 37.2 20.4 53 53 A P T 34 S+ 0 0 88 0, 0.0 -1,-0.1 0, 0.0 -5,-0.0 0.748 121.7 62.0 -58.4 -24.6 1.8 35.7 23.0 54 54 A D T 34 S+ 0 0 97 1,-0.2 3,-0.1 -22,-0.1 0, 0.0 0.658 116.5 31.6 -73.6 -14.7 -1.1 36.8 20.9 55 55 A Q T <4 S+ 0 0 67 -3,-2.3 -22,-2.3 1,-0.3 2,-0.3 0.740 130.5 9.7-103.2 -42.1 0.2 34.6 18.1 56 56 A I E < +c 33 0A 3 -4,-2.6 -1,-0.3 -24,-0.2 2,-0.3 -0.983 57.2 178.1-155.2 130.9 1.9 31.7 19.9 57 57 A Q E -c 34 0A 70 -24,-2.3 -22,-2.8 -2,-0.3 2,-0.4 -0.855 22.5-124.9-127.0 166.6 2.1 30.3 23.4 58 58 A F E -c 35 0A 40 -2,-0.3 2,-0.4 -24,-0.2 -22,-0.2 -0.880 16.8-173.4-110.5 141.7 3.7 27.3 25.2 59 59 A F E -c 36 0A 48 -24,-2.4 -22,-0.7 -2,-0.4 2,-0.4 -0.971 26.6-127.2-134.5 119.7 2.0 24.8 27.5 60 60 A Q E +c 37 0A 107 -2,-0.4 2,-0.3 -24,-0.2 -22,-0.2 -0.528 49.5 143.3 -71.0 125.7 4.1 22.2 29.4 61 61 A H - 0 0 7 -24,-2.0 2,-0.6 -2,-0.4 -48,-0.3 -0.931 47.5-142.0-166.9 134.5 2.7 18.7 28.6 62 62 A D > - 0 0 47 -2,-0.3 3,-2.7 -24,-0.2 6,-0.1 -0.907 24.6-140.4 -95.6 121.0 3.9 15.2 28.1 63 63 A S T 3 S+ 0 0 6 -2,-0.6 56,-0.1 1,-0.3 57,-0.1 0.701 100.9 66.2 -64.0 -16.7 1.6 13.8 25.3 64 64 A S T 3 S+ 0 0 40 1,-0.1 2,-0.9 55,-0.1 -1,-0.3 0.625 80.8 95.7 -72.7 -12.4 1.5 10.5 27.2 65 65 A D <> - 0 0 76 -3,-2.7 4,-1.0 1,-0.2 -1,-0.1 -0.692 56.3-170.6 -86.6 97.5 -0.4 12.3 30.1 66 66 A E H >> S+ 0 0 98 -2,-0.9 3,-1.0 1,-0.2 4,-0.8 0.925 83.5 46.4 -56.4 -53.5 -4.1 11.8 29.5 67 67 A D H >> S+ 0 0 102 1,-0.3 4,-1.3 2,-0.2 3,-0.8 0.912 106.4 60.4 -65.7 -31.0 -5.5 14.2 32.1 68 68 A G H 3> S+ 0 0 3 1,-0.2 4,-2.3 2,-0.2 -1,-0.3 0.759 91.6 68.9 -65.8 -23.8 -3.1 16.9 30.9 69 69 A W H - 0 0 33 -2,-0.3 4,-0.6 55,-0.2 54,-0.2 -0.296 40.6-105.4 -66.1 160.8 15.1 -4.6 17.3 98 98 A V T >4 S+ 0 0 114 52,-0.3 3,-1.4 1,-0.2 -1,-0.1 0.952 124.0 56.0 -50.3 -47.6 11.9 -6.3 18.3 99 99 A E T 34 S+ 0 0 165 1,-0.3 -1,-0.2 54,-0.0 -3,-0.0 0.859 113.9 38.4 -52.5 -42.2 14.1 -9.1 19.7 100 100 A E T 34 S+ 0 0 108 -3,-0.1 2,-0.5 2,-0.1 -1,-0.3 0.301 85.1 117.0-102.3 10.8 16.0 -6.7 21.9 101 101 A T << - 0 0 27 -3,-1.4 2,-0.1 -4,-0.6 -3,-0.0 -0.655 57.8-139.2 -80.1 121.6 13.2 -4.3 23.1 102 102 A T > - 0 0 65 -2,-0.5 4,-2.5 1,-0.1 5,-0.1 -0.482 20.1-117.9 -71.3 157.7 12.6 -4.4 26.8 103 103 A T H > S+ 0 0 93 1,-0.2 4,-2.8 2,-0.2 5,-0.2 0.892 117.1 54.4 -65.0 -34.4 9.0 -4.3 28.0 104 104 A A H > S+ 0 0 75 2,-0.2 4,-2.4 1,-0.2 -1,-0.2 0.938 109.8 46.4 -64.5 -40.7 9.8 -1.0 29.8 105 105 A E H > S+ 0 0 48 2,-0.2 4,-2.5 1,-0.2 5,-0.2 0.912 112.3 52.1 -63.3 -48.1 11.1 0.5 26.5 106 106 A W H X S+ 0 0 99 -4,-2.5 4,-2.4 2,-0.2 5,-0.2 0.954 112.6 43.2 -49.7 -52.8 8.0 -0.9 24.7 107 107 A R H X S+ 0 0 169 -4,-2.8 4,-2.2 1,-0.2 -2,-0.2 0.891 113.3 52.6 -66.5 -40.9 5.5 0.6 27.2 108 108 A K H X S+ 0 0 143 -4,-2.4 4,-1.4 -5,-0.2 -1,-0.2 0.928 112.6 43.4 -62.9 -44.4 7.4 3.9 27.3 109 109 A L H X S+ 0 0 0 -4,-2.5 4,-3.0 1,-0.2 5,-0.4 0.923 113.5 50.4 -68.9 -43.2 7.4 4.4 23.5 110 110 A L H X>S+ 0 0 29 -4,-2.4 5,-2.9 -5,-0.2 4,-1.9 0.878 104.5 60.4 -66.0 -31.0 3.8 3.3 23.1 111 111 A A H <>S+ 0 0 23 -4,-2.2 5,-1.2 -5,-0.2 -1,-0.2 0.937 118.0 27.2 -61.7 -44.2 2.8 5.7 25.8 112 112 A V H <5S+ 0 0 17 -4,-1.4 5,-0.3 3,-0.2 -2,-0.2 0.961 129.0 38.4 -78.3 -51.2 4.0 8.7 23.8 113 113 A N H <5S+ 0 0 0 -4,-3.0 -3,-0.2 -5,-0.2 -2,-0.2 0.691 133.8 14.7 -82.4 -22.7 3.8 7.6 20.2 114 114 A L T X5S+ 0 0 39 -4,-1.9 4,-2.4 -5,-0.4 -3,-0.2 0.744 128.3 41.6-120.6 -62.6 0.5 5.7 20.4 115 115 A D H > S+ 0 0 5 -5,-0.3 4,-2.8 2,-0.2 5,-0.2 0.871 114.0 51.0 -71.2 -38.9 -1.8 10.3 19.6 118 118 A F H X S+ 0 0 81 -4,-2.4 4,-3.2 2,-0.2 5,-0.3 0.953 111.1 47.5 -60.1 -50.6 -5.0 8.3 20.6 119 119 A F H X S+ 0 0 23 -4,-3.3 4,-2.3 1,-0.2 5,-0.3 0.932 116.5 44.3 -59.3 -43.2 -5.7 10.7 23.6 120 120 A G H X S+ 0 0 0 -4,-2.0 4,-2.5 -5,-0.2 -1,-0.2 0.905 115.1 46.6 -70.4 -42.5 -5.2 13.7 21.4 121 121 A T H X S+ 0 0 5 -4,-2.8 4,-2.4 2,-0.2 -2,-0.2 0.922 114.0 48.1 -62.7 -50.6 -7.2 12.4 18.4 122 122 A R H X S+ 0 0 90 -4,-3.2 4,-2.1 -5,-0.2 -2,-0.2 0.930 117.0 42.1 -55.5 -51.2 -10.1 11.3 20.7 123 123 A L H X S+ 0 0 15 -4,-2.3 4,-2.5 -5,-0.3 5,-0.3 0.921 111.9 55.6 -66.9 -41.3 -10.2 14.6 22.5 124 124 A G H X S+ 0 0 0 -4,-2.5 4,-2.3 -5,-0.3 5,-0.3 0.922 107.8 48.0 -55.3 -44.2 -9.7 16.6 19.4 125 125 A I H X S+ 0 0 25 -4,-2.4 4,-1.9 1,-0.2 -1,-0.2 0.950 113.0 48.5 -62.7 -46.4 -12.7 15.0 17.8 126 126 A Q H < S+ 0 0 113 -4,-2.1 -1,-0.2 1,-0.2 -2,-0.2 0.872 119.3 38.2 -61.4 -38.5 -14.9 15.6 20.8 127 127 A R H < S+ 0 0 65 -4,-2.5 -1,-0.2 1,-0.1 -2,-0.2 0.702 122.7 39.5 -85.9 -28.2 -13.8 19.3 21.1 128 128 A M H >< S+ 0 0 0 -4,-2.3 3,-0.8 -5,-0.3 5,-0.4 0.646 86.8 108.3-100.0 -16.9 -13.7 20.2 17.4 129 129 A K T 3< S+ 0 0 68 -4,-1.9 50,-0.2 -5,-0.3 49,-0.1 -0.306 83.4 7.9 -67.2 145.6 -16.8 18.3 15.9 130 130 A N T 3 S+ 0 0 104 48,-2.3 -1,-0.2 47,-0.2 49,-0.1 0.701 94.8 107.6 65.9 28.5 -19.9 20.2 14.8 131 131 A K S < S- 0 0 109 -3,-0.8 -2,-0.1 47,-0.5 -1,-0.1 0.391 83.8-120.3-116.2 1.9 -18.4 23.7 15.2 132 132 A G S S+ 0 0 68 46,-0.2 47,-0.1 -4,-0.1 -3,-0.1 0.752 72.7 129.8 63.7 30.4 -17.9 24.8 11.5 133 133 A L S S- 0 0 49 -5,-0.4 -1,-0.1 46,-0.2 3,-0.1 0.536 74.8-120.8 -89.9 -10.9 -14.2 25.2 12.1 134 134 A G - 0 0 12 45,-0.2 46,-0.1 1,-0.1 45,-0.1 0.972 46.3-157.4 61.7 52.0 -12.9 23.2 9.2 135 135 A A E - e 0 180A 1 44,-1.8 46,-1.9 -7,-0.2 2,-0.4 -0.301 16.1-172.1 -71.9 143.6 -11.2 21.1 11.9 136 136 A S E -de 85 181A 0 -52,-2.0 -50,-2.2 44,-0.2 2,-0.5 -0.981 14.4-163.4-143.8 128.1 -8.2 19.1 11.0 137 137 A I E -de 86 182A 0 44,-3.0 46,-2.1 -2,-0.4 2,-0.6 -0.957 11.2-167.9-109.9 122.3 -6.2 16.5 13.0 138 138 A I E -de 87 183A 0 -52,-3.2 -50,-2.3 -2,-0.5 2,-0.6 -0.959 3.5-162.6-118.6 115.0 -2.7 15.8 11.5 139 139 A N E -de 88 184A 0 44,-2.7 46,-1.8 -2,-0.6 2,-0.5 -0.861 18.4-131.5-104.4 121.3 -1.0 12.7 13.0 140 140 A M E + e 0 185A 11 -52,-2.2 46,-0.2 -2,-0.6 22,-0.1 -0.634 37.6 163.3 -73.2 120.1 2.8 12.3 12.4 141 141 A S - 0 0 0 44,-3.5 45,-0.2 -2,-0.5 22,-0.2 0.390 27.8-144.2-134.1 2.9 3.2 8.7 11.2 142 142 A S > - 0 0 14 43,-0.7 3,-2.0 2,-0.2 4,-0.2 0.708 34.8 -84.9 63.7 155.7 6.7 8.3 9.6 143 143 A I G >> S+ 0 0 2 44,-1.9 3,-1.9 1,-0.3 4,-1.9 0.817 127.1 71.7 -54.2 -26.5 8.2 6.4 6.7 144 144 A E G 34 S+ 0 0 5 43,-0.3 16,-0.3 1,-0.3 -1,-0.3 0.407 83.1 66.7 -76.4 4.3 8.3 3.8 9.5 145 145 A G G <4 S+ 0 0 6 -3,-2.0 -1,-0.3 14,-0.2 -2,-0.2 0.475 111.0 34.2 -93.1 -5.7 4.6 3.5 9.2 146 146 A F T <4 S+ 0 0 71 -3,-1.9 2,-0.3 1,-0.3 -2,-0.2 0.692 124.7 27.7-112.1 -44.8 5.1 2.0 5.7 147 147 A V S < S- 0 0 56 -4,-1.9 -1,-0.3 2,-0.0 2,-0.1 -0.914 76.7-118.7-120.6 157.1 8.3 0.0 5.9 148 148 A G - 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