==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 03-MAY-05 1ZKQ . COMPND 2 MOLECULE: THIOREDOXIN REDUCTASE 2, MITOCHONDRIAL; . SOURCE 2 ORGANISM_SCIENTIFIC: MUS MUSCULUS; . AUTHOR E.I.BITEROVA,A.A.TURANOV,V.N.GLADYSHEV,J.J.BARYCKI . 482 1 1 1 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 22505.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 349 72.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 42 8.7 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 58 12.0 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 4 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 45 9.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 51 10.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 125 25.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 11 2.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 1 3 0 1 0 0 0 3 1 0 0 1 0 0 0 0 0 1 0 0 1 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 3 0 2 4 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 5 0 3 0 3 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 1 1 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 37 A Q 0 0 89 0, 0.0 143,-0.1 0, 0.0 140,-0.0 0.000 360.0 360.0 360.0-147.6 -29.1 57.2 22.1 2 38 A Q - 0 0 106 1,-0.2 142,-0.6 141,-0.1 2,-0.1 0.052 360.0 -74.5 -79.0-164.0 -30.0 53.5 22.1 3 39 A S E -a 144 0A 67 140,-0.1 2,-0.3 127,-0.0 142,-0.3 -0.382 39.0-151.9 -92.4 173.7 -29.1 51.1 19.3 4 40 A F E -a 145 0A 11 140,-0.8 142,-1.2 -2,-0.1 143,-0.3 -0.924 29.7-115.4-138.9 161.3 -30.5 50.7 15.8 5 41 A D E S+ 0 0 64 23,-1.3 142,-1.4 -2,-0.3 2,-0.4 0.916 106.3 20.1 -64.0 -40.4 -30.8 47.8 13.5 6 42 A L E -ab 147 29A 0 22,-1.8 24,-1.8 140,-0.1 2,-0.4 -0.994 65.0-168.6-136.2 135.9 -28.4 49.7 11.2 7 43 A L E -ab 148 30A 5 140,-1.9 142,-2.3 -2,-0.4 2,-0.5 -0.986 7.8-164.1-124.3 128.5 -26.0 52.5 11.7 8 44 A V E -ab 149 31A 0 22,-2.9 24,-2.2 -2,-0.4 2,-0.8 -0.952 8.3-153.3-118.2 122.0 -24.4 54.4 8.8 9 45 A I E S+ab 150 32A 9 140,-2.6 142,-2.8 -2,-0.5 24,-0.2 -0.832 73.9 32.5 -94.6 110.3 -21.3 56.6 9.2 10 46 A G - 0 0 7 22,-3.3 2,-1.1 -2,-0.8 23,-0.2 0.482 67.7-140.4 110.1 107.5 -21.3 59.3 6.5 11 47 A G + 0 0 0 4,-0.2 36,-2.1 20,-0.1 37,-0.5 -0.551 63.7 103.8 -96.8 69.3 -24.5 60.8 5.1 12 48 A G S >>S- 0 0 8 -2,-1.1 4,-2.7 139,-0.3 5,-0.5 -0.548 87.7 -48.7-129.4-164.4 -23.5 61.0 1.5 13 49 A S H >5S+ 0 0 29 34,-0.5 4,-1.0 1,-0.2 5,-0.1 0.849 134.1 29.9 -35.9 -62.2 -24.1 59.3 -1.9 14 50 A G H >5S+ 0 0 7 2,-0.2 4,-2.0 1,-0.1 -1,-0.2 0.946 122.6 46.6 -69.8 -51.6 -23.5 55.8 -0.6 15 51 A G H >5S+ 0 0 1 136,-0.4 4,-2.9 1,-0.2 5,-0.2 0.925 109.6 51.5 -58.7 -50.8 -24.6 56.1 3.0 16 52 A L H X5S+ 0 0 4 -4,-2.7 4,-2.4 1,-0.2 -1,-0.2 0.845 110.8 50.6 -58.0 -34.0 -27.9 57.9 2.4 17 53 A A H X<>S+ 0 0 0 -4,-2.6 5,-1.7 1,-0.2 3,-0.7 0.921 113.8 50.1 -59.0 -43.1 -32.8 49.9 5.1 23 59 A A H ><5S+ 0 0 13 -4,-3.8 3,-1.0 1,-0.3 -1,-0.2 0.831 108.6 52.5 -63.5 -32.9 -35.3 52.4 6.5 24 60 A Q H 3<5S+ 0 0 115 -4,-1.5 -1,-0.3 -5,-0.3 -2,-0.2 0.667 99.9 63.8 -76.3 -17.2 -37.8 51.4 3.8 25 61 A L T <<5S- 0 0 63 -4,-1.1 -1,-0.3 -3,-0.7 -2,-0.2 0.085 124.9-102.0 -92.4 21.9 -37.3 47.8 4.7 26 62 A G T < 5S+ 0 0 55 -3,-1.0 2,-0.3 1,-0.2 -3,-0.2 0.738 79.4 134.9 66.6 25.5 -38.8 48.5 8.1 27 63 A K < - 0 0 80 -5,-1.7 2,-1.0 -23,-0.0 -1,-0.2 -0.792 62.5-113.1-106.6 149.5 -35.5 48.6 10.0 28 64 A K - 0 0 128 -2,-0.3 -22,-1.8 -3,-0.1 -23,-1.3 -0.704 45.2-175.7 -84.4 107.8 -34.5 51.3 12.5 29 65 A V E -b 6 0A 3 -2,-1.0 88,-1.2 86,-0.5 2,-0.3 -0.728 15.3-171.7-107.8 154.7 -31.7 53.2 10.9 30 66 A A E -bc 7 117A 0 -24,-1.8 -22,-2.9 -2,-0.3 2,-0.4 -0.994 2.9-167.4-141.7 144.0 -29.4 55.9 12.1 31 67 A V E -bc 8 118A 0 86,-2.0 88,-2.6 -2,-0.3 2,-0.5 -0.999 6.1-162.2-137.5 137.5 -26.9 58.0 10.2 32 68 A A E +bc 9 119A 5 -24,-2.2 -22,-3.3 -2,-0.4 2,-0.4 -0.976 15.0 172.5-118.4 128.3 -24.1 60.4 11.4 33 69 A D + 0 0 19 86,-0.7 2,-0.4 -2,-0.5 89,-0.1 -0.979 4.0 176.4-139.1 123.1 -22.6 62.9 9.0 34 70 A Y - 0 0 64 -2,-0.4 2,-1.1 87,-0.1 87,-0.1 -0.993 20.7-147.8-129.7 130.5 -20.2 65.6 9.9 35 71 A V - 0 0 12 -2,-0.4 9,-0.2 9,-0.2 3,-0.1 -0.676 11.6-157.2 -99.7 83.1 -18.5 68.0 7.5 36 72 A E - 0 0 83 -2,-1.1 6,-0.1 1,-0.1 -2,-0.0 -0.420 33.2-114.0 -56.7 116.7 -15.1 68.8 8.9 37 73 A P - 0 0 46 0, 0.0 6,-0.2 0, 0.0 -1,-0.1 0.121 29.4 -98.6 -49.4 168.2 -14.4 72.2 7.1 38 74 A S > - 0 0 6 4,-1.9 3,-3.0 1,-0.1 -3,-0.0 -0.498 36.1-100.1 -89.6 161.2 -11.7 72.6 4.5 39 75 A P T 3 S+ 0 0 82 0, 0.0 -1,-0.1 0, 0.0 131,-0.1 0.853 129.2 50.3 -46.9 -37.7 -8.3 74.2 5.3 40 76 A R T 3 S- 0 0 114 2,-0.0 130,-0.0 1,-0.0 126,-0.0 0.593 127.3-104.3 -78.7 -10.7 -9.6 77.4 3.8 41 77 A G < + 0 0 56 -3,-3.0 2,-0.3 1,-0.3 -1,-0.0 0.798 66.7 148.5 95.1 30.8 -12.7 77.1 6.0 42 78 A T + 0 0 8 -6,-0.1 -4,-1.9 2,-0.0 2,-0.3 -0.740 15.4 168.1 -97.9 147.8 -15.5 75.9 3.7 43 79 A K - 0 0 61 -2,-0.3 2,-0.3 -6,-0.2 -7,-0.1 -0.968 6.9-178.0-152.0 163.7 -18.3 73.7 5.0 44 80 A W - 0 0 30 -2,-0.3 -9,-0.2 -9,-0.2 3,-0.1 -0.931 22.9 -84.5-156.8 179.3 -21.7 72.4 3.8 45 81 A G - 0 0 19 -2,-0.3 3,-0.4 1,-0.2 -1,-0.1 0.208 59.8 -51.2 -79.4-163.5 -24.8 70.4 4.5 46 82 A L S S+ 0 0 0 1,-0.2 -1,-0.2 55,-0.1 61,-0.2 -0.355 96.1 71.4 -71.6 150.8 -26.0 66.8 4.2 47 83 A G S > S- 0 0 1 -36,-2.1 4,-0.8 -3,-0.1 -34,-0.5 0.324 86.2-113.7 126.5 -9.1 -25.5 64.9 1.0 48 84 A G H > - 0 0 15 -37,-0.5 4,-2.0 -3,-0.4 5,-0.3 -0.135 55.2 -45.1 77.5-175.1 -21.8 64.1 0.6 49 85 A T H >>S+ 0 0 37 1,-0.2 4,-3.0 2,-0.2 5,-1.0 0.905 130.1 56.1 -59.8 -49.9 -19.3 65.4 -1.9 50 86 A a H >5S+ 0 0 14 3,-0.2 6,-1.8 1,-0.2 4,-0.6 0.889 112.9 41.6 -51.8 -46.6 -21.3 64.9 -5.0 51 87 A V H <5S+ 0 0 11 -4,-0.8 -1,-0.2 4,-0.1 -2,-0.2 0.901 130.8 23.4 -69.0 -44.0 -24.2 67.1 -3.7 52 88 A N H <5S+ 0 0 0 -4,-2.0 -3,-0.2 -7,-0.1 -2,-0.2 0.866 141.7 4.3 -96.6 -40.4 -22.1 69.7 -2.2 53 89 A V H <5S+ 0 0 2 -4,-3.0 -3,-0.2 -5,-0.3 -4,-0.1 0.084 120.4 45.7-137.9 27.8 -18.7 69.8 -3.8 54 90 A G S X S+ 0 0 48 1,-0.2 4,-3.3 3,-0.2 5,-0.3 0.855 124.4 47.5 -39.4 -58.4 -21.0 66.2 -9.5 56 92 A I H > S+ 0 0 39 -6,-1.8 4,-2.5 2,-0.2 5,-0.2 0.966 116.7 36.7 -56.6 -64.6 -23.7 68.7 -9.1 57 93 A P H > S+ 0 0 1 0, 0.0 4,-2.2 0, 0.0 5,-0.2 0.906 120.3 50.8 -56.0 -42.1 -21.8 72.0 -8.7 58 94 A K H X S+ 0 0 18 -4,-2.4 4,-2.5 1,-0.2 3,-0.3 0.977 111.5 45.8 -59.0 -58.6 -19.3 70.9 -11.2 59 95 A K H X S+ 0 0 73 -4,-3.3 4,-2.3 -5,-0.3 -1,-0.2 0.853 113.9 49.8 -54.5 -39.8 -21.9 69.9 -13.8 60 96 A L H X S+ 0 0 65 -4,-2.5 4,-1.3 -5,-0.3 -1,-0.2 0.854 111.7 46.2 -71.0 -35.2 -23.8 73.1 -13.4 61 97 A M H X S+ 0 0 0 -4,-2.2 4,-2.1 -3,-0.3 -2,-0.2 0.844 111.4 52.9 -75.4 -30.5 -20.8 75.4 -13.7 62 98 A H H X S+ 0 0 4 -4,-2.5 4,-2.8 -5,-0.2 -2,-0.2 0.948 106.8 53.2 -64.5 -45.2 -19.7 73.4 -16.7 63 99 A Q H X S+ 0 0 82 -4,-2.3 4,-2.2 -5,-0.2 -1,-0.2 0.859 105.2 56.7 -57.4 -33.9 -23.3 74.1 -18.0 64 100 A A H X S+ 0 0 20 -4,-1.3 4,-1.1 2,-0.2 -2,-0.2 0.989 108.8 42.8 -61.5 -58.9 -22.5 77.7 -17.4 65 101 A A H >X S+ 0 0 14 -4,-2.1 4,-1.2 1,-0.2 3,-0.5 0.867 111.0 56.9 -55.6 -40.0 -19.4 77.8 -19.6 66 102 A L H >X S+ 0 0 55 -4,-2.8 4,-2.1 1,-0.3 3,-1.1 0.944 100.1 57.7 -58.3 -46.8 -21.2 75.8 -22.2 67 103 A L H 3X S+ 0 0 77 -4,-2.2 4,-1.6 1,-0.3 -1,-0.3 0.815 99.3 61.4 -52.8 -32.2 -23.9 78.4 -22.4 68 104 A G H X S+ 0 0 23 -4,-2.3 4,-1.2 1,-0.3 3,-0.7 0.841 100.8 72.0 -51.6 -34.9 -23.3 80.0 -31.9 74 110 A A H ><>S+ 0 0 21 -4,-1.5 5,-2.3 1,-0.3 3,-0.5 0.875 92.4 52.2 -49.6 -47.3 -26.5 81.9 -31.4 75 111 A H H X<5S+ 0 0 98 -3,-1.2 3,-1.3 -4,-0.9 -1,-0.3 0.837 102.6 59.6 -63.7 -32.1 -25.5 84.7 -33.7 76 112 A H H <<5S+ 0 0 80 -4,-0.8 -1,-0.2 -3,-0.7 -2,-0.2 0.847 104.0 50.3 -65.0 -34.3 -24.8 82.3 -36.5 77 113 A Y T <<5S- 0 0 114 -4,-1.2 -1,-0.3 -3,-0.5 -2,-0.2 0.326 133.4 -87.3 -86.6 7.4 -28.3 80.9 -36.5 78 114 A G T < 5S+ 0 0 53 -3,-1.3 2,-1.0 1,-0.2 -3,-0.2 0.495 80.9 140.0 104.6 3.1 -29.8 84.5 -36.7 79 115 A W < - 0 0 185 -5,-2.3 2,-2.5 -6,-0.2 -1,-0.2 -0.726 43.8-149.3 -85.9 105.2 -30.0 85.5 -33.0 80 116 A E + 0 0 201 -2,-1.0 2,-0.4 -3,-0.1 -1,-0.1 -0.411 33.6 163.4 -74.0 69.3 -28.9 89.1 -33.0 81 117 A V - 0 0 51 -2,-2.5 2,-1.1 -10,-0.2 4,-0.1 -0.772 50.1-109.0 -93.2 133.2 -27.4 89.0 -29.5 82 118 A A - 0 0 78 -2,-0.4 -1,-0.1 1,-0.2 -2,-0.1 -0.473 33.0-150.5 -62.7 97.0 -25.1 91.9 -28.5 83 119 A Q S S+ 0 0 81 -2,-1.1 2,-3.2 1,-0.2 -1,-0.2 0.740 78.5 85.4 -42.4 -43.5 -21.8 89.8 -28.6 84 120 A P + 0 0 128 0, 0.0 2,-0.6 0, 0.0 -1,-0.2 -0.371 65.2 160.3 -66.5 78.2 -19.9 91.8 -25.9 85 121 A V - 0 0 75 -2,-3.2 -2,-0.1 -4,-0.1 2,-0.1 -0.901 24.8-157.6-109.7 110.7 -21.6 89.7 -23.2 86 122 A Q - 0 0 191 -2,-0.6 2,-0.4 2,-0.0 119,-0.1 -0.291 3.5-147.5 -78.9 165.7 -20.0 89.6 -19.7 87 123 A H - 0 0 83 117,-0.2 2,-0.5 -2,-0.1 -2,-0.0 -0.999 7.1-152.6-135.2 129.9 -20.5 86.8 -17.1 88 124 A N > - 0 0 87 -2,-0.4 4,-1.4 1,-0.1 3,-0.5 -0.926 10.4-148.8-115.9 127.4 -20.4 87.4 -13.4 89 125 A W H > S+ 0 0 11 -2,-0.5 4,-2.7 1,-0.2 5,-0.3 0.719 91.7 65.3 -54.6 -32.3 -19.4 84.8 -10.9 90 126 A K H > S+ 0 0 123 2,-0.2 4,-2.8 1,-0.2 -1,-0.2 0.948 103.3 44.2 -62.0 -50.8 -21.7 86.0 -8.2 91 127 A T H > S+ 0 0 92 -3,-0.5 4,-2.9 2,-0.2 5,-0.2 0.960 116.1 47.4 -57.8 -54.0 -25.0 85.3 -10.0 92 128 A M H X S+ 0 0 15 -4,-1.4 4,-3.0 1,-0.2 5,-0.2 0.952 114.2 45.6 -52.2 -57.8 -23.8 81.9 -11.1 93 129 A A H X S+ 0 0 4 -4,-2.7 4,-3.3 1,-0.2 5,-0.3 0.922 111.7 52.9 -52.7 -49.6 -22.5 80.9 -7.7 94 130 A E H X S+ 0 0 105 -4,-2.8 4,-2.3 -5,-0.3 -1,-0.2 0.953 113.3 44.0 -50.6 -54.3 -25.7 82.1 -6.0 95 131 A A H X S+ 0 0 61 -4,-2.9 4,-1.5 2,-0.2 -2,-0.2 0.910 116.1 45.4 -58.7 -49.0 -27.8 80.0 -8.4 96 132 A V H X S+ 0 0 7 -4,-3.0 4,-2.2 -5,-0.2 -1,-0.2 0.943 113.3 50.2 -62.8 -47.6 -25.6 76.9 -8.2 97 133 A Q H X S+ 0 0 29 -4,-3.3 4,-2.1 -5,-0.2 -2,-0.2 0.878 106.2 55.0 -58.9 -42.0 -25.4 77.1 -4.4 98 134 A N H X S+ 0 0 76 -4,-2.3 4,-1.7 -5,-0.3 -1,-0.2 0.888 109.4 47.7 -60.9 -39.1 -29.1 77.5 -3.9 99 135 A H H X S+ 0 0 83 -4,-1.5 4,-1.4 2,-0.2 -1,-0.2 0.925 107.0 56.3 -67.5 -42.8 -29.8 74.3 -5.8 100 136 A V H X S+ 0 0 2 -4,-2.2 4,-1.1 1,-0.2 3,-0.4 0.901 107.2 50.7 -54.0 -40.9 -27.1 72.5 -3.8 101 137 A K H X S+ 0 0 75 -4,-2.1 4,-2.6 1,-0.2 5,-0.4 0.884 99.4 62.7 -66.1 -38.9 -29.1 73.5 -0.7 102 138 A S H X S+ 0 0 66 -4,-1.7 4,-2.3 1,-0.3 -1,-0.2 0.851 105.3 50.0 -52.4 -36.1 -32.4 72.2 -2.2 103 139 A L H X S+ 0 0 47 -4,-1.4 4,-1.9 -3,-0.4 -1,-0.3 0.836 106.4 54.0 -73.4 -33.6 -30.6 68.8 -2.1 104 140 A N H >X S+ 0 0 10 -4,-1.1 4,-2.1 -3,-0.3 3,-0.5 0.991 118.0 35.0 -61.5 -59.3 -29.5 69.3 1.5 105 141 A W H 3X S+ 0 0 154 -4,-2.6 4,-2.5 1,-0.2 5,-0.2 0.865 112.3 62.4 -63.4 -35.0 -33.1 69.9 2.6 106 142 A G H 3X S+ 0 0 30 -4,-2.3 4,-1.1 -5,-0.4 -1,-0.2 0.875 107.9 43.7 -58.1 -36.9 -34.3 67.5 0.1 107 143 A H H S+ 0 0 4 -4,-2.8 5,-1.6 2,-0.2 -2,-0.2 0.836 113.8 48.3 -73.5 -32.5 -34.6 61.0 6.1 112 148 A Q H ><5S+ 0 0 139 -4,-2.5 3,-1.1 -5,-0.2 -2,-0.2 0.948 111.0 49.4 -70.4 -49.7 -37.5 62.5 8.2 113 149 A D H 3<5S+ 0 0 115 -4,-2.6 -1,-0.2 1,-0.3 -2,-0.2 0.746 115.7 42.1 -62.6 -27.0 -40.2 60.8 6.1 114 150 A R T 3<5S- 0 0 77 -4,-1.2 -1,-0.3 -5,-0.1 -2,-0.2 0.443 116.6-120.8 -98.0 -0.2 -38.6 57.4 6.3 115 151 A K T < 5 + 0 0 166 -3,-1.1 -86,-0.5 1,-0.2 2,-0.4 0.988 50.4 160.8 58.0 84.0 -37.8 58.1 10.0 116 152 A V < - 0 0 11 -5,-1.6 2,-0.2 -88,-0.1 -86,-0.2 -0.966 41.3-124.0-134.5 113.8 -34.1 57.9 10.3 117 153 A K E -c 30 0A 98 -88,-1.2 -86,-2.0 -2,-0.4 2,-0.6 -0.416 26.8-150.7 -61.7 124.0 -32.5 59.6 13.3 118 154 A Y E -c 31 0A 67 -2,-0.2 2,-0.7 -88,-0.2 -86,-0.2 -0.880 14.1-173.9-103.8 113.9 -29.9 62.0 12.0 119 155 A F E -c 32 0A 19 -88,-2.6 2,-3.6 -2,-0.6 -86,-0.7 -0.855 15.9-155.0-111.0 99.2 -26.9 62.7 14.2 120 156 A N + 0 0 42 -2,-0.7 2,-0.4 -88,-0.2 16,-0.4 -0.371 55.3 129.2 -69.3 69.3 -24.7 65.5 12.8 121 157 A I - 0 0 16 -2,-3.6 2,-0.9 14,-0.1 14,-0.2 -0.992 64.0-126.2-131.7 133.3 -21.8 64.0 14.7 122 158 A K B -H 134 0B 60 12,-1.1 12,-0.8 -2,-0.4 -89,-0.1 -0.705 39.0-144.6 -83.8 108.8 -18.4 63.0 13.5 123 159 A A + 0 0 13 -2,-0.9 2,-0.2 10,-0.2 10,-0.2 -0.022 26.4 172.7 -70.7 172.5 -17.9 59.4 14.4 124 160 A S - 0 0 16 8,-0.2 8,-2.8 166,-0.1 166,-0.2 -0.791 36.3-104.0-176.9 133.4 -15.0 57.3 15.6 125 161 A F B +D 131 0A 0 164,-3.3 6,-0.2 -2,-0.2 168,-0.1 -0.284 31.7 171.4 -69.3 152.4 -15.0 53.7 16.9 126 162 A V S S- 0 0 57 4,-1.6 2,-0.2 1,-0.4 5,-0.2 0.539 74.6 -13.2-123.7 -40.6 -14.6 52.8 20.5 127 163 A D S S- 0 0 67 3,-1.3 -1,-0.4 167,-0.0 166,-0.0 -0.640 87.9 -75.1-143.3-160.1 -15.3 49.1 20.2 128 164 A E S S+ 0 0 87 -2,-0.2 166,-0.1 1,-0.2 3,-0.1 0.570 125.8 26.2 -87.2 -10.6 -16.7 46.6 17.6 129 165 A H S S+ 0 0 71 1,-0.1 16,-1.5 15,-0.0 2,-0.3 0.281 115.2 63.7-132.7 7.6 -20.4 47.6 18.0 130 166 A T E - 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0 0 22 -3,-1.5 29,-2.2 28,-0.2 -4,-0.1 0.989 10.3-135.4 75.3 72.8 -16.4 40.8 -32.6 423 459 A L B -W 450 0H 69 -4,-0.4 -6,-3.0 27,-0.2 2,-0.5 -0.248 23.1-113.5 -55.3 141.9 -17.6 41.4 -29.1 424 460 A V E + V 0 416G 11 25,-1.8 -8,-0.3 -8,-0.2 3,-0.1 -0.696 33.6 178.5 -84.0 125.7 -17.3 45.0 -28.0 425 461 A L E - 0 0 19 -10,-3.0 -51,-2.8 -2,-0.5 2,-0.3 0.775 64.7 -8.7 -96.7 -34.5 -14.8 45.6 -25.3 426 462 A G E -SV 373 415G 0 -11,-2.0 -11,-2.3 -53,-0.3 2,-0.4 -0.974 54.5-150.2-163.1 151.9 -14.9 49.4 -24.9 427 463 A L E -SV 372 414G 2 -55,-2.8 -55,-1.9 -2,-0.3 2,-0.4 -0.982 10.2-163.9-129.0 139.7 -16.4 52.5 -26.5 428 464 A H E -SV 371 413G 3 -15,-2.8 -15,-1.9 -2,-0.4 2,-0.4 -0.982 6.7-178.2-131.3 125.8 -15.0 56.0 -26.5 429 465 A F E -SV 370 412G 0 -59,-3.1 -59,-2.6 -2,-0.4 2,-0.5 -0.975 6.7-177.5-125.5 133.1 -16.9 59.1 -27.4 430 466 A L E +S 369 0G 0 -19,-1.2 -19,-0.2 -2,-0.4 -61,-0.2 -0.977 48.3 60.5-130.6 115.1 -15.6 62.7 -27.6 431 467 A G S > S- 0 0 0 -63,-2.4 3,-0.6 -2,-0.5 -63,-0.5 -0.977 86.8 -14.5 161.8-166.2 -18.0 65.4 -28.4 432 468 A P T 3 S+ 0 0 29 0, 0.0 5,-0.1 0, 0.0 32,-0.1 -0.315 122.8 3.6 -64.5 139.5 -21.3 67.2 -27.3 433 469 A N T 3> S+ 0 0 99 1,-0.1 4,-1.7 3,-0.1 5,-0.1 0.929 75.7 169.4 51.8 54.6 -23.4 65.4 -24.7 434 470 A A H <> S+ 0 0 0 -3,-0.6 4,-2.9 1,-0.2 5,-0.2 0.871 74.5 47.7 -65.6 -42.2 -20.9 62.5 -24.2 435 471 A G H > S+ 0 0 20 2,-0.2 4,-1.9 1,-0.2 -1,-0.2 0.865 109.0 55.7 -67.9 -35.2 -22.6 61.1 -21.1 436 472 A E H > S+ 0 0 141 1,-0.2 4,-0.5 2,-0.2 -2,-0.2 0.895 114.5 40.1 -63.7 -38.4 -25.9 61.3 -22.9 437 473 A V H X S+ 0 0 17 -4,-1.7 4,-0.8 1,-0.1 3,-0.2 0.934 113.5 50.8 -75.8 -48.2 -24.5 59.2 -25.7 438 474 A T H X S+ 0 0 1 -4,-2.9 4,-1.3 1,-0.2 3,-0.5 0.861 93.5 73.8 -61.0 -41.7 -22.4 56.7 -23.8 439 475 A Q H >X S+ 0 0 123 -4,-1.9 3,-1.8 1,-0.2 4,-1.0 0.882 96.4 46.5 -38.7 -65.3 -25.1 55.6 -21.4 440 476 A G H >X S+ 0 0 52 -4,-0.5 4,-1.2 1,-0.3 3,-0.7 0.859 108.6 55.6 -50.3 -41.9 -27.2 53.5 -23.8 441 477 A F H 3X S+ 0 0 54 -4,-0.8 4,-2.0 -3,-0.5 -1,-0.3 0.749 96.4 66.7 -66.0 -20.5 -24.1 51.8 -25.2 442 478 A A H S+ 0 0 24 -4,-1.2 5,-3.0 1,-0.2 4,-0.4 0.919 109.5 42.9 -61.8 -42.0 -25.1 47.2 -25.0 445 481 A I H ><5S+ 0 0 19 -4,-2.0 3,-0.8 1,-0.2 -2,-0.2 0.851 108.8 56.8 -73.1 -34.6 -21.9 46.1 -23.3 446 482 A K H 3<5S+ 0 0 98 -4,-2.3 -1,-0.2 1,-0.3 -2,-0.2 0.725 111.2 47.0 -68.1 -18.8 -23.6 44.7 -20.3 447 483 A C T 3<5S- 0 0 106 -4,-1.0 -1,-0.3 -3,-0.3 -2,-0.2 0.506 119.3-109.7 -98.7 -10.0 -25.6 42.5 -22.7 448 484 A G T < 5 - 0 0 33 -3,-0.8 -3,-0.2 -4,-0.4 -2,-0.1 0.731 45.8-170.1 87.1 24.5 -22.6 41.4 -24.8 449 485 A A < - 0 0 21 -5,-3.0 -25,-1.8 -6,-0.2 2,-0.3 0.042 7.5-144.9 -43.9 154.0 -23.3 43.4 -27.9 450 486 A S B > -W 423 0H 9 -27,-0.2 4,-2.3 1,-0.1 3,-0.3 -0.874 23.7-117.2-125.3 159.3 -21.2 42.6 -31.0 451 487 A Y H > S+ 0 0 12 -29,-2.2 4,-2.5 -30,-0.4 5,-0.2 0.844 118.4 60.1 -62.0 -31.6 -19.8 44.7 -33.8 452 488 A A H > S+ 0 0 41 -31,-1.4 4,-1.1 1,-0.2 -1,-0.3 0.909 107.2 44.9 -60.3 -42.9 -21.9 42.6 -36.1 453 489 A Q H 4 S+ 0 0 82 -3,-0.3 -2,-0.2 2,-0.2 -1,-0.2 0.866 108.4 57.5 -70.4 -34.0 -24.9 43.8 -34.1 454 490 A V H >< S+ 0 0 14 -4,-2.3 3,-1.4 1,-0.2 -2,-0.2 0.924 106.0 50.1 -61.8 -41.4 -23.5 47.4 -34.3 455 491 A M H 3< S+ 0 0 122 -4,-2.5 -1,-0.2 1,-0.3 -2,-0.2 0.790 109.7 50.7 -66.8 -29.1 -23.5 47.2 -38.1 456 492 A Q T 3< S+ 0 0 147 -4,-1.1 2,-0.7 -5,-0.2 -1,-0.3 0.312 90.6 95.4 -91.0 9.5 -27.1 46.0 -38.0 457 493 A T S < S- 0 0 70 -3,-1.4 -1,-0.0 12,-0.2 -4,-0.0 -0.881 71.8-141.7-105.0 107.0 -28.2 48.8 -35.8 458 494 A V - 0 0 135 -2,-0.7 2,-0.2 1,-0.1 -2,-0.1 -0.265 19.0-122.5 -64.9 150.4 -29.6 51.8 -37.8 459 495 A G - 0 0 27 10,-0.1 2,-0.7 7,-0.0 -1,-0.1 -0.534 12.5-115.6 -96.4 163.4 -28.7 55.3 -36.7 460 496 A I - 0 0 125 -2,-0.2 6,-0.4 0, 0.0 3,-0.3 -0.881 49.7-114.8 -96.2 118.2 -30.9 58.2 -35.7 461 497 A H S S+ 0 0 151 -2,-0.7 3,-0.1 1,-0.3 2,-0.0 -0.900 87.4 19.4-111.8 134.7 -30.3 60.9 -38.2 462 498 A P S S+ 0 0 62 0, 0.0 -1,-0.3 0, 0.0 2,-0.3 0.401 96.1 101.7-105.3 138.1 -29.1 63.4 -37.8 463 499 A T - 0 0 47 -3,-0.3 4,-0.3 1,-0.1 -4,-0.0 -0.931 68.3-115.3-153.8 172.6 -27.2 63.0 -34.5 464 500 A C S >> S+ 0 0 19 -2,-0.3 3,-1.9 1,-0.2 4,-0.6 0.903 110.5 60.1 -82.0 -45.3 -23.7 62.5 -33.1 465 501 A S H >> S+ 0 0 36 1,-0.3 3,-1.0 2,-0.2 4,-0.9 0.784 90.9 69.2 -54.0 -28.8 -24.5 59.1 -31.6 466 502 A E H >> S+ 0 0 20 -6,-0.4 4,-1.3 1,-0.3 3,-0.6 0.855 89.3 65.2 -60.1 -29.9 -25.4 57.7 -35.0 467 503 A E H <> S+ 0 0 41 -3,-1.9 4,-0.9 -4,-0.3 3,-0.3 0.874 93.1 60.7 -57.5 -37.3 -21.7 58.0 -35.8 468 504 A V H << S+ 0 0 0 -3,-1.0 3,-0.4 -4,-0.6 -1,-0.3 0.894 109.6 41.7 -56.6 -39.4 -21.1 55.4 -33.1 469 505 A V H << S+ 0 0 20 -4,-0.9 -1,-0.2 -3,-0.6 -2,-0.2 0.656 108.8 59.0 -83.1 -18.8 -23.2 53.0 -35.2 470 506 A K H < S+ 0 0 95 -4,-1.3 -1,-0.2 -3,-0.3 -2,-0.2 0.541 73.5 130.8 -89.2 -6.6 -21.7 54.0 -38.6 471 507 A L < + 0 0 5 -4,-0.9 -78,-0.1 -3,-0.4 3,-0.1 -0.209 11.8 141.9 -51.8 129.1 -18.2 53.1 -37.6 472 508 A H + 0 0 128 -80,-0.3 2,-0.8 1,-0.1 -1,-0.2 0.466 38.2 94.9-143.6 -21.0 -16.6 50.9 -40.3 473 509 A I - 0 0 22 -81,-0.4 -81,-2.3 8,-0.1 -1,-0.1 -0.720 58.0-156.6 -87.5 109.7 -12.9 52.0 -40.6 474 510 A S B -U 391 0G 13 -2,-0.8 5,-0.4 -83,-0.2 4,-0.3 -0.345 21.9-128.3 -79.3 162.1 -10.5 49.9 -38.5 475 511 A K S > S+ 0 0 58 -85,-2.2 3,-1.3 1,-0.2 -1,-0.1 0.847 109.2 59.4 -76.3 -33.9 -7.1 51.1 -37.3 476 512 A R T 3 S+ 0 0 88 1,-0.3 -1,-0.2 -86,-0.3 -85,-0.1 0.913 94.6 63.2 -59.9 -44.3 -5.5 47.9 -38.7 477 513 A S T 3 S- 0 0 62 1,-0.1 -1,-0.3 2,-0.0 -2,-0.2 0.727 98.6-141.4 -52.7 -24.5 -6.8 48.8 -42.2 478 514 A G < + 0 0 65 -3,-1.3 -1,-0.1 -4,-0.3 -3,-0.1 0.387 48.9 146.8 76.3 -4.3 -4.6 51.9 -42.0 479 515 A L - 0 0 112 -5,-0.4 -1,-0.2 1,-0.1 -2,-0.0 -0.183 60.0 -87.3 -66.6 156.2 -7.3 53.9 -43.8 480 516 A E - 0 0 121 1,-0.1 -1,-0.1 -3,-0.1 -7,-0.0 -0.416 32.7-148.2 -62.2 128.0 -8.1 57.6 -43.2 481 517 A P 0 0 20 0, 0.0 -87,-1.8 0, 0.0 -1,-0.1 0.448 360.0 360.0 -81.7 1.4 -10.6 57.9 -40.3 482 518 A T 0 0 123 -89,-0.2 -87,-0.1 -87,-0.0 -2,-0.0 -0.630 360.0 360.0 -98.0 360.0 -12.3 61.1 -41.5