==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=21-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER LYASE (OXO-ACID) 09-JAN-96 1ZSC . COMPND 2 MOLECULE: CARBONIC ANHYDRASE II; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR C.A.LESBURG,D.W.CHRISTIANSON . 257 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 11512.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 170 66.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 18 7.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 57 22.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 27 10.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 37 14.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 16 6.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 2 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 2 2 1 1 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 4 A H 0 0 173 0, 0.0 2,-0.1 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 -46.8 9.6 0.2 8.5 2 5 A W + 0 0 41 2,-0.1 2,-0.2 1,-0.1 7,-0.2 -0.423 360.0 137.4 -77.5 154.5 7.6 -1.4 11.3 3 6 A G - 0 0 6 5,-3.0 10,-0.1 2,-0.2 58,-0.1 -0.796 62.4 -80.3-165.2-151.7 5.4 -4.4 10.5 4 7 A Y S S+ 0 0 35 -2,-0.2 5,-0.2 5,-0.2 237,-0.1 0.199 83.0 109.7-120.3 17.7 4.4 -7.8 11.7 5 8 A G S > S- 0 0 36 1,-0.1 4,-1.5 4,-0.1 3,-0.3 -0.308 84.3 -96.8 -88.7 178.1 7.3 -9.9 10.5 6 9 A K T 4 S+ 0 0 168 1,-0.2 -1,-0.1 2,-0.2 5,-0.0 0.819 123.0 39.1 -62.4 -30.2 10.1 -11.7 12.4 7 10 A H T 4 S+ 0 0 157 1,-0.1 -1,-0.2 4,-0.0 -3,-0.0 0.691 131.2 20.8 -98.5 -14.5 12.4 -8.7 11.7 8 11 A N T 4 S+ 0 0 62 -3,-0.3 -5,-3.0 -6,-0.1 -2,-0.2 0.143 95.8 120.9-138.6 17.7 10.2 -5.7 12.2 9 12 A G S >X S- 0 0 2 -4,-1.5 3,-3.1 -5,-0.2 4,-0.7 -0.082 81.2 -68.2 -79.0-174.7 7.3 -7.0 14.3 10 13 A P G >4 S+ 0 0 29 0, 0.0 3,-0.8 0, 0.0 4,-0.4 0.744 126.4 61.1 -43.2 -39.3 5.8 -6.2 17.7 11 14 A E G 34 S+ 0 0 158 1,-0.2 3,-0.1 2,-0.1 -5,-0.1 0.696 108.6 44.6 -67.6 -15.7 8.9 -7.4 19.6 12 15 A H G X4 S+ 0 0 58 -3,-3.1 3,-1.8 1,-0.1 4,-0.5 0.553 85.4 92.5-101.2 -15.3 11.0 -4.8 17.8 13 16 A W G XX S+ 0 0 4 -3,-0.8 4,-2.5 -4,-0.7 3,-0.9 0.784 71.5 70.3 -54.4 -33.1 8.7 -1.7 18.1 14 17 A H G 34 S+ 0 0 66 -4,-0.4 -1,-0.3 1,-0.2 7,-0.1 0.755 86.9 67.9 -57.5 -26.5 10.2 -0.4 21.3 15 18 A K G <4 S+ 0 0 133 -3,-1.8 -1,-0.2 1,-0.2 -2,-0.2 0.904 117.4 22.0 -64.4 -38.3 13.4 0.6 19.5 16 19 A D T <4 S+ 0 0 110 -3,-0.9 -2,-0.2 -4,-0.5 -1,-0.2 0.694 135.9 37.7 -97.7 -24.6 11.7 3.3 17.5 17 20 A F >< - 0 0 44 -4,-2.5 3,-2.3 1,-0.1 -1,-0.2 -0.753 62.8-179.1-132.6 83.2 8.7 3.8 19.8 18 21 A P G > S+ 0 0 97 0, 0.0 3,-1.9 0, 0.0 -1,-0.1 0.728 76.6 75.9 -52.7 -30.2 9.9 3.5 23.4 19 22 A I G > S+ 0 0 63 1,-0.3 3,-3.1 179,-0.2 -5,-0.1 0.707 72.2 89.3 -59.7 -14.4 6.3 4.1 24.7 20 23 A A G < S+ 0 0 5 -3,-2.3 -1,-0.3 1,-0.3 -6,-0.1 0.744 90.2 44.1 -52.6 -27.7 5.8 0.4 23.6 21 24 A K G < S+ 0 0 137 -3,-1.9 -1,-0.3 -4,-0.1 -2,-0.2 0.016 95.5 133.0-105.9 24.5 6.9 -0.5 27.1 22 25 A G S X S- 0 0 14 -3,-3.1 3,-0.5 1,-0.1 -3,-0.0 0.044 70.4-102.3 -69.5-178.2 4.7 2.1 28.7 23 26 A E T 3 S+ 0 0 106 1,-0.2 226,-0.3 225,-0.1 -1,-0.1 0.643 112.7 37.3 -81.1 -21.4 2.4 1.9 31.6 24 27 A R T 3 S+ 0 0 45 224,-0.1 -1,-0.2 168,-0.1 2,-0.2 -0.300 79.1 151.9-131.6 56.8 -0.9 1.9 29.6 25 28 A Q < - 0 0 4 -3,-0.5 220,-0.1 221,-0.3 170,-0.1 -0.492 32.8-103.8 -87.4 150.6 -0.3 -0.2 26.5 26 29 A S S S+ 0 0 0 168,-0.5 2,-0.2 -2,-0.2 78,-0.1 -0.901 76.0 45.0-125.6 160.7 -2.9 -2.2 24.6 27 30 A P + 0 0 0 0, 0.0 218,-3.0 0, 0.0 2,-0.3 0.544 64.9 176.5 -79.2-178.9 -4.2 -4.8 23.8 28 31 A V - 0 0 1 216,-0.3 77,-1.2 -2,-0.2 2,-0.4 -0.934 35.9-101.3-142.9 161.3 -4.6 -6.7 27.1 29 32 A D E -a 105 0A 38 216,-0.4 2,-0.8 -2,-0.3 77,-0.2 -0.742 33.9-136.7 -84.2 132.8 -6.1 -10.0 28.2 30 33 A I E -a 106 0A 0 75,-2.9 77,-2.8 -2,-0.4 2,-1.0 -0.863 12.6-159.4 -95.8 107.6 -9.5 -9.5 29.8 31 34 A D >> - 0 0 64 -2,-0.8 4,-1.4 75,-0.2 3,-1.3 -0.810 4.1-159.1 -86.3 104.7 -9.8 -11.7 32.9 32 35 A T T 34 S+ 0 0 47 -2,-1.0 -1,-0.1 1,-0.3 222,-0.0 0.713 86.3 52.0 -61.2 -21.6 -13.5 -12.0 33.3 33 36 A H T 34 S+ 0 0 162 1,-0.2 -1,-0.3 -3,-0.1 -2,-0.0 0.629 112.9 44.8 -91.3 -10.1 -13.3 -12.9 37.0 34 37 A T T <4 S+ 0 0 98 -3,-1.3 -2,-0.2 2,-0.1 2,-0.2 0.607 86.9 106.6-104.9 -15.8 -11.1 -10.0 37.9 35 38 A A S < S- 0 0 18 -4,-1.4 2,-0.6 216,-0.1 218,-0.2 -0.474 71.7-128.1 -66.4 134.3 -13.1 -7.4 35.9 36 39 A K E -c 253 0B 106 216,-2.3 218,-2.4 -2,-0.2 2,-0.3 -0.739 10.2-134.3 -92.7 111.9 -15.0 -5.2 38.3 37 40 A Y E -c 254 0B 107 -2,-0.6 218,-0.2 216,-0.2 220,-0.1 -0.530 24.2-162.4 -62.2 124.4 -18.7 -4.8 37.6 38 41 A D > - 0 0 30 216,-2.7 3,-1.6 -2,-0.3 -1,-0.1 -0.904 14.4-168.3-117.8 107.7 -19.3 -1.0 37.9 39 42 A P T 3 S+ 0 0 96 0, 0.0 -1,-0.1 0, 0.0 216,-0.0 0.644 83.8 66.8 -69.0 -14.5 -22.9 0.1 38.4 40 43 A S T 3 S+ 0 0 73 2,-0.1 2,-0.5 40,-0.0 215,-0.1 0.480 74.3 110.8 -84.0 -2.3 -22.2 3.7 37.8 41 44 A L < - 0 0 33 -3,-1.6 3,-0.1 213,-0.2 38,-0.1 -0.659 64.8-138.5 -75.2 125.6 -21.3 3.0 34.1 42 45 A K - 0 0 137 37,-0.9 39,-0.1 -2,-0.5 2,-0.1 -0.250 28.5 -91.2 -78.2 159.6 -23.9 4.5 31.7 43 46 A P - 0 0 114 0, 0.0 36,-1.9 0, 0.0 2,-0.2 -0.422 47.8-103.0 -69.2 154.5 -25.1 2.6 28.7 44 47 A L E -D 78 0B 17 34,-0.3 2,-0.5 141,-0.3 34,-0.2 -0.567 28.7-149.4 -73.6 146.6 -23.2 3.3 25.5 45 48 A S E -D 77 0B 49 32,-3.1 32,-2.1 -2,-0.2 2,-0.6 -0.941 14.3-176.0-120.5 109.2 -24.9 5.6 23.0 46 49 A V E +D 76 0B 34 -2,-0.5 2,-0.6 30,-0.2 30,-0.2 -0.905 4.1 179.2-107.4 113.6 -24.1 4.8 19.3 47 50 A S E +D 75 0B 37 28,-2.9 28,-2.2 -2,-0.6 3,-0.2 -0.780 23.0 143.1-118.0 89.1 -25.6 7.2 16.9 48 51 A Y > + 0 0 3 -2,-0.6 3,-1.1 26,-0.2 130,-0.3 0.077 34.6 108.8-111.1 20.3 -24.4 6.2 13.4 49 52 A D T 3 S+ 0 0 98 1,-0.2 -1,-0.1 128,-0.1 25,-0.1 0.766 85.0 42.3 -71.1 -23.9 -27.6 7.0 11.5 50 53 A Q T 3 S+ 0 0 124 23,-1.0 -1,-0.2 -3,-0.2 24,-0.2 0.147 84.0 145.6-106.7 19.8 -26.0 10.0 9.7 51 54 A A < - 0 0 21 -3,-1.1 2,-0.5 22,-0.1 123,-0.1 -0.243 32.8-160.3 -60.4 136.0 -22.7 8.2 9.0 52 55 A T - 0 0 59 16,-0.3 16,-2.9 122,-0.1 2,-0.2 -0.892 3.8-164.9-122.7 97.9 -20.9 9.2 5.7 53 56 A S E +E 67 0B 1 -2,-0.5 121,-0.6 122,-0.3 14,-0.3 -0.581 12.8 171.5 -78.5 147.3 -18.3 6.6 4.5 54 57 A L E + 0 0 76 12,-3.1 118,-2.9 1,-0.4 2,-0.3 0.708 50.5 3.0-121.7 -45.0 -16.0 8.0 1.8 55 58 A R E -EF 66 171B 86 11,-1.0 11,-3.0 116,-0.3 2,-0.4 -0.964 44.3-144.3-151.2 154.4 -13.1 5.6 1.0 56 59 A I E -EF 65 170B 0 114,-2.6 114,-2.4 -2,-0.3 2,-0.4 -0.972 28.7-176.8-120.3 140.1 -11.5 2.3 1.7 57 60 A L E -EF 64 169B 30 7,-2.2 7,-2.3 -2,-0.4 2,-0.8 -0.998 29.4-139.2-143.9 139.3 -7.7 2.1 1.7 58 61 A N E -E 63 0B 0 110,-2.8 109,-2.7 -2,-0.4 5,-0.2 -0.859 22.7-178.6 -93.9 113.2 -4.9 -0.5 2.0 59 62 A N - 0 0 53 3,-2.2 4,-0.1 -2,-0.8 -1,-0.1 0.299 50.7-101.9 -97.7 9.0 -2.3 1.2 4.2 60 63 A G S S+ 0 0 4 2,-0.5 3,-0.1 166,-0.2 106,-0.1 0.306 117.5 51.9 92.1 -16.5 0.2 -1.6 4.2 61 64 A H S S- 0 0 40 1,-0.6 2,-0.3 -58,-0.1 166,-0.1 0.566 125.7 -26.6-122.3 -21.5 -0.7 -2.8 7.7 62 65 A A S S- 0 0 7 -5,-0.1 -3,-2.2 165,-0.1 -1,-0.6 -0.874 70.2 -92.8-169.4-175.7 -4.6 -3.2 7.4 63 66 A F E -E 58 0B 0 -2,-0.3 29,-0.6 -5,-0.2 2,-0.4 -0.951 36.6-158.9-116.7 137.3 -7.4 -1.7 5.4 64 67 A N E -EG 57 91B 22 -7,-2.3 -7,-2.2 -2,-0.4 2,-0.6 -0.969 11.6-150.3-116.6 139.5 -9.3 1.3 6.7 65 68 A V E -EG 56 90B 0 25,-2.5 25,-1.8 -2,-0.4 2,-0.3 -0.950 27.2-149.2-105.1 127.1 -12.8 2.5 5.8 66 69 A E E -EG 55 89B 48 -11,-3.0 -12,-3.1 -2,-0.6 -11,-1.0 -0.779 9.8-157.9-103.7 148.7 -12.8 6.3 6.3 67 70 A F E -E 53 0B 7 21,-2.5 2,-0.7 -2,-0.3 -14,-0.2 -0.814 29.9-101.8-123.9 156.4 -15.6 8.5 7.3 68 71 A D + 0 0 48 -16,-2.9 -16,-0.3 -2,-0.3 5,-0.3 -0.686 40.5 172.5 -76.3 116.2 -16.5 12.1 6.9 69 72 A D + 0 0 43 -2,-0.7 -1,-0.1 1,-0.2 17,-0.1 -0.142 44.4 107.4-117.6 33.7 -15.7 13.6 10.4 70 73 A S S S+ 0 0 79 1,-0.1 2,-0.3 56,-0.0 -1,-0.2 0.462 89.1 22.1 -87.5 -6.2 -16.2 17.3 9.7 71 74 A Q S S- 0 0 132 -3,-0.2 2,-2.5 3,-0.1 3,-0.4 -0.967 98.7 -86.1-152.8 163.8 -19.4 17.3 11.6 72 75 A D S S+ 0 0 88 -2,-0.3 3,-0.2 1,-0.2 -3,-0.1 -0.393 76.6 126.5 -70.4 64.2 -21.2 15.3 14.3 73 76 A K S S+ 0 0 20 -2,-2.5 -23,-1.0 1,-0.3 2,-0.4 0.760 74.8 26.7 -96.3 -26.2 -22.7 12.7 11.9 74 77 A A S S+ 0 0 2 -3,-0.4 13,-2.5 -24,-0.2 -1,-0.3 -0.932 85.4 165.3-135.0 106.4 -21.6 9.4 13.4 75 78 A V E -DH 47 86B 13 -28,-2.2 -28,-2.9 -2,-0.4 2,-0.4 -0.893 30.2-151.7-129.8 163.2 -20.9 9.7 17.1 76 79 A L E +DH 46 85B 0 9,-2.4 9,-2.2 -2,-0.3 2,-0.3 -0.987 28.7 149.2-129.5 130.6 -20.3 7.7 20.3 77 80 A K E +D 45 0B 69 -32,-2.1 -32,-3.1 -2,-0.4 7,-0.1 -0.900 35.4 45.3-149.9 177.7 -21.2 8.9 23.8 78 81 A G E > S+D 44 0B 24 5,-0.3 3,-2.3 3,-0.3 -34,-0.3 -0.426 71.6 82.8 82.5-155.7 -22.2 7.6 27.1 79 82 A G T 3 S- 0 0 2 -36,-1.9 -37,-0.9 1,-0.3 -1,-0.1 -0.283 121.0 -24.8 55.3-136.3 -20.6 4.6 28.7 80 83 A P T 3 S+ 0 0 38 0, 0.0 -1,-0.3 0, 0.0 2,-0.2 0.433 116.0 110.8 -87.2 4.4 -17.4 5.7 30.5 81 84 A L < - 0 0 18 -3,-2.3 2,-0.4 -39,-0.1 -3,-0.3 -0.474 51.9-160.2 -87.1 149.8 -17.1 8.7 28.2 82 85 A D + 0 0 132 -2,-0.2 2,-0.0 53,-0.1 -3,-0.0 -0.962 68.4 8.5-118.6 131.9 -17.5 12.4 28.9 83 86 A G S S- 0 0 45 -2,-0.4 2,-0.4 39,-0.1 -5,-0.3 -0.235 98.0 -59.4 90.3 175.9 -18.2 14.4 25.7 84 87 A T - 0 0 25 -7,-0.1 38,-2.2 -9,-0.0 2,-0.5 -0.873 41.0-158.1-105.8 138.2 -18.9 13.4 22.2 85 88 A Y E -HI 76 121B 5 -9,-2.2 -9,-2.4 -2,-0.4 2,-0.4 -0.963 10.5-143.5-118.2 126.7 -16.5 11.3 20.1 86 89 A R E -HI 75 120B 48 34,-2.5 34,-2.0 -2,-0.5 2,-0.3 -0.747 18.7-119.7 -91.5 137.3 -16.7 11.3 16.2 87 90 A L E + I 0 119B 1 -13,-2.5 32,-0.3 -2,-0.4 -13,-0.1 -0.540 37.4 166.3 -73.3 129.8 -16.1 8.2 14.2 88 91 A I E - 0 0 34 30,-2.8 -21,-2.5 1,-0.4 2,-0.3 0.718 60.5 -20.5-112.6 -38.1 -13.1 8.8 11.8 89 92 A Q E -GI 66 118B 34 29,-1.3 29,-3.1 -23,-0.2 -1,-0.4 -0.994 47.3-147.1-164.0 160.0 -12.3 5.2 10.6 90 93 A F E +GI 65 117B 0 -25,-1.8 -25,-2.5 -2,-0.3 2,-0.3 -0.970 22.3 165.7-130.7 153.3 -12.7 1.5 11.3 91 94 A H E -GI 64 116B 22 25,-1.9 25,-3.2 -2,-0.3 2,-0.3 -0.947 22.7-125.1-155.0 168.6 -10.3 -1.4 10.5 92 95 A F E - 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