data_16011 ####################### # Entry information # ####################### save_entry_information _Saveframe_category entry_information _Entry_title ; NMR Spectroscopic Characterization of 13C, 15N-labeled Ribonuclease A in urea 8M ; _BMRB_accession_number 16011 _BMRB_flat_file_name bmr16011.str _Entry_type original _Submission_date 2008-10-30 _Accession_date 2008-10-30 _Entry_origination author _NMR_STAR_version 2.1.1 _Experimental_method NMR _Details . loop_ _Author_ordinal _Author_family_name _Author_given_name _Author_middle_initials _Author_family_title 1 Lopez-Alonso Jorge P. . 2 Bruix Marta . . 3 Font Josep . . 4 Ribo Marc . . 5 Vilanova Maria . . 6 Morbio Manuela . . 7 Jimenez Maria A. . 8 Rico Manuel . . 9 Santoro Jorge . . 10 Gonzalez Carlos . . 11 Laurents Douglas V. . stop_ loop_ _Saveframe_category_type _Saveframe_category_type_count assigned_chemical_shifts 1 stop_ loop_ _Data_type _Data_type_count "1H chemical shifts" 112 "13C chemical shifts" 239 "15N chemical shifts" 112 stop_ loop_ _Revision_date _Revision_keyword _Revision_author _Revision_detail 2010-10-18 original author . stop_ loop_ _Related_BMRB_accession_number _Relationship 1072 'ribonuclease A' 16010 'Ribonuclease A in 40% Acetic Acid' 2928 'ribonuclease A' 4031 'bovine pancreatic ribonuclease A' 4032 'bovine pancreatic [C65S,C72S] ribonuclease A' 443 'ribonuclease A' stop_ _Original_release_date 2010-10-18 save_ ############################# # Citation for this entry # ############################# save_entry_citation _Saveframe_category entry_citation _Citation_full . _Citation_title 'NMR spectroscopy reveals that RNase A is chiefly denatured in 40% acetic acid: implications for oligomer formation by 3D domain swapping.' _Citation_status published _Citation_type journal _CAS_abstract_code . _MEDLINE_UI_code . _PubMed_ID 20085318 loop_ _Author_ordinal _Author_family_name _Author_given_name _Author_middle_initials _Author_family_title 1 Lopez-Alonso 'Jorge Pedro' . . 2 Bruix Marta . . 3 Font Josep . . 4 Ribo Marc . . 5 Vilanova Maria . . 6 Jimenez 'Maria Angeles' . . 7 Santoro Jorge . . 8 Gonzalez Carlos . . 9 Laurents Douglas V. . stop_ _Journal_abbreviation 'J. Am. Chem. Soc.' _Journal_name_full 'Journal of the American Chemical Society' _Journal_volume 132 _Journal_issue 5 _Journal_CSD . _Book_chapter_title . _Book_volume . _Book_series . _Book_ISBN . _Conference_state_province . _Conference_abstract_number . _Page_first 1621 _Page_last 1630 _Year 2010 _Details . save_ ################################## # Molecular system description # ################################## save_assembly _Saveframe_category molecular_system _Mol_system_name 'bovine pancreas ribonuclease A' _Enzyme_commission_number . loop_ _Mol_system_component_name _Mol_label 'ribonuclease A' $ribonuclease_A stop_ _System_molecular_weight . _System_physical_state unfolded _System_oligomer_state ? _System_paramagnetic no _System_thiol_state . _Database_query_date . _Details . save_ ######################## # Monomeric polymers # ######################## save_ribonuclease_A _Saveframe_category monomeric_polymer _Mol_type polymer _Mol_polymer_class protein _Name_common ribonuclease_A _Molecular_mass . _Mol_thiol_state 'all disulfide bound' _Details . ############################## # Polymer residue sequence # ############################## _Residue_count 124 _Mol_residue_sequence ; KETAAAKFERQHMDSSTSAA SSSNYCNQMMKSRNLTKDRC KPVNTFVHESLADVQAVCSQ KNVACKNGQTNCYQSYSTMS ITDCRETGSSKYPNCAYKTT QANKHIIVACEGNPYVPVHF DASV ; loop_ _Residue_seq_code _Residue_label 1 LYS 2 GLU 3 THR 4 ALA 5 ALA 6 ALA 7 LYS 8 PHE 9 GLU 10 ARG 11 GLN 12 HIS 13 MET 14 ASP 15 SER 16 SER 17 THR 18 SER 19 ALA 20 ALA 21 SER 22 SER 23 SER 24 ASN 25 TYR 26 CYS 27 ASN 28 GLN 29 MET 30 MET 31 LYS 32 SER 33 ARG 34 ASN 35 LEU 36 THR 37 LYS 38 ASP 39 ARG 40 CYS 41 LYS 42 PRO 43 VAL 44 ASN 45 THR 46 PHE 47 VAL 48 HIS 49 GLU 50 SER 51 LEU 52 ALA 53 ASP 54 VAL 55 GLN 56 ALA 57 VAL 58 CYS 59 SER 60 GLN 61 LYS 62 ASN 63 VAL 64 ALA 65 CYS 66 LYS 67 ASN 68 GLY 69 GLN 70 THR 71 ASN 72 CYS 73 TYR 74 GLN 75 SER 76 TYR 77 SER 78 THR 79 MET 80 SER 81 ILE 82 THR 83 ASP 84 CYS 85 ARG 86 GLU 87 THR 88 GLY 89 SER 90 SER 91 LYS 92 TYR 93 PRO 94 ASN 95 CYS 96 ALA 97 TYR 98 LYS 99 THR 100 THR 101 GLN 102 ALA 103 ASN 104 LYS 105 HIS 106 ILE 107 ILE 108 VAL 109 ALA 110 CYS 111 GLU 112 GLY 113 ASN 114 PRO 115 TYR 116 VAL 117 PRO 118 VAL 119 HIS 120 PHE 121 ASP 122 ALA 123 SER 124 VAL stop_ _Sequence_homology_query_date . _Sequence_homology_query_revised_last_date 2015-08-05 loop_ _Database_name _Database_accession_code _Database_entry_mol_name _Sequence_query_to_submitted_percentage _Sequence_subject_length _Sequence_identity _Sequence_positive _Sequence_homology_expectation_value BMRB 1072 "ribonuclease A" 100.00 124 100.00 100.00 1.53e-85 BMRB 16010 ribonuclease_A 100.00 124 100.00 100.00 1.53e-85 BMRB 16503 RNase_A 100.00 124 100.00 100.00 1.53e-85 BMRB 16742 "Ribonuclease A" 100.00 126 100.00 100.00 9.58e-86 BMRB 17099 ribonuclease 100.00 124 100.00 100.00 1.53e-85 BMRB 17172 RNase_A_C-dimer 100.00 124 100.00 100.00 1.53e-85 BMRB 19065 RnaseA 100.00 124 100.00 100.00 1.53e-85 BMRB 2928 "ribonuclease A" 100.00 124 100.00 100.00 1.53e-85 BMRB 385 "ribonuclease A" 100.00 124 100.00 100.00 1.53e-85 BMRB 4031 "bovine pancreatic ribonuclease A" 100.00 124 100.00 100.00 1.53e-85 BMRB 4032 "bovine pancreatic [C65S,C72S] ribonuclease A" 100.00 124 98.39 98.39 1.75e-83 BMRB 443 "ribonuclease A" 100.00 124 100.00 100.00 1.53e-85 PDB 1A2W "Crystal Structure Of A 3d Domain-Swapped Dimer Of Bovine Pancreatic Ribonuclease A" 100.00 124 100.00 100.00 1.53e-85 PDB 1A5P "C[40,95]a Variant Of Bovine Pancreatic Ribonuclease A" 100.00 124 98.39 98.39 1.02e-83 PDB 1A5Q "P93a Variant Of Bovine Pancreatic Ribonuclease A" 100.00 124 99.19 99.19 1.69e-84 PDB 1AFK "Crystal Structure Of Ribonuclease A In Complex With 5'- Diphosphoadenosine-3'-Phosphate" 100.00 124 100.00 100.00 1.53e-85 PDB 1AFL "Ribonuclease A In Complex With 5'-Diphosphoadenosine 2'- Phosphate At 1.7 Angstrom Resolution" 100.00 124 100.00 100.00 1.53e-85 PDB 1AFU "Structure Of Ribonuclease A At 2.0 Angstroms From Monoclinic Crystals" 100.00 124 100.00 100.00 1.53e-85 PDB 1AQP "Ribonuclease A Copper Complex" 100.00 124 100.00 100.00 1.53e-85 PDB 1BEL "Hydrolase Phosphoric Diester, Rna" 100.00 124 100.00 100.00 1.53e-85 PDB 1BZQ "Complex Of A Dromedary Single-Domain Vhh Antibody Fragment With Rnase A" 100.00 124 100.00 100.00 1.53e-85 PDB 1C0B "Bovine Pancreatic Ribonuclease A Desiccated For 2.5 Days" 100.00 128 100.00 100.00 1.48e-85 PDB 1C0C "Bovine Pancreatic Ribonuclease A Desiccated For 4.0 Days" 100.00 128 100.00 100.00 1.48e-85 PDB 1C8W "Thr45gly Variant Of Ribonuclease A" 100.00 124 99.19 99.19 1.59e-84 PDB 1C9V "H12a Variant Of Ribonuclease A" 100.00 124 99.19 99.19 3.48e-84 PDB 1C9X "H119a Variant Of Ribonuclease A" 100.00 124 99.19 99.19 3.48e-84 PDB 1CJQ "X-Ray Crystallographic Studies Of The Denaturation Of The Denaturation Of Ribonuclease S." 81.45 101 100.00 100.00 1.70e-68 PDB 1CJR "X-Ray Crystallographic Studies Of Denaturation In Ribonuclease S" 80.65 101 100.00 100.00 7.42e-68 PDB 1D5D "The Role Of Phenylalanine 8 In The Stabilization Of The S Protein-S Peptide Interaction: Packing And Cavities" 81.45 101 100.00 100.00 1.70e-68 PDB 1D5E "The Role Of Phenylalanine 8 In The Stabilization Of The S Protein-S Peptide Interaction: Packing And Cavities" 81.45 101 100.00 100.00 1.70e-68 PDB 1D5H "Rnase S(F8a). Mutant Ribonuclease S" 81.45 101 100.00 100.00 1.70e-68 PDB 1DFJ "Ribonuclease Inhibitor Complexed With Ribonuclease A" 100.00 124 100.00 100.00 1.53e-85 PDB 1DY5 "Deamidated Derivative Of Bovine Pancreatic Ribonuclease" 100.00 124 99.19 99.19 1.45e-84 PDB 1EIC "Crystal Structure Of F120a Mutant Of Bovine Pancreatic Ribonuclease A" 100.00 124 99.19 99.19 3.30e-84 PDB 1EID "Crystal Structure Of F120g Mutant Of Bovine Pancreatic Ribonuclease A" 100.00 124 99.19 99.19 3.76e-84 PDB 1EIE "Crystal Structure Of F120w Mutant Of Bovine Pancreatic Ribonuclease A" 100.00 124 99.19 100.00 4.93e-85 PDB 1EOS "Crystal Structure Of Ribonuclease A Complexed With Uridylyl(2',5')guanosine (Productive Binding)" 100.00 124 100.00 100.00 1.53e-85 PDB 1EOW "Crystal Structure Of Ribonuclease A Complexed With Uridylyl(2',5')guanosine (Non-Productive Binding)" 100.00 124 100.00 100.00 1.53e-85 PDB 1F0V "Crystal Structure Of An Rnase A Dimer Displaying A New Type Of 3d Domain Swapping" 100.00 124 100.00 100.00 1.53e-85 PDB 1FEV "Crystal Structure Of The Ala4aib Mutation In Rnase S" 81.45 101 100.00 100.00 1.70e-68 PDB 1FS3 "Crystal Structure Of Wild-Type Bovine Pancreatic Ribonuclease A" 100.00 124 100.00 100.00 1.53e-85 PDB 1IZP "F46l Mutant Of Bovine Pancreatic Ribonuclease A" 100.00 124 99.19 99.19 7.31e-85 PDB 1IZQ "F46v Mutant Of Bovine Pancreatic Ribonuclease A" 100.00 124 99.19 99.19 1.42e-84 PDB 1IZR "F46a Mutant Of Bovine Pancreatic Ribonuclease A" 100.00 124 99.19 99.19 3.30e-84 PDB 1J7Z "Osmolyte Stabilization Of Ribonuclease" 83.87 104 100.00 100.00 3.09e-70 PDB 1J80 "Osmolyte Stabilization Of Rnase" 83.87 104 100.00 100.00 3.09e-70 PDB 1J81 "Osmolyte Stabilization Of Rnase" 83.87 104 100.00 100.00 3.09e-70 PDB 1J82 "Osmolyte Stabilization Of Rnase" 83.87 104 100.00 100.00 3.09e-70 PDB 1JN4 "The Crystal Structure Of Ribonuclease A In Complex With 2'- Deoxyuridine 3'-Pyrophosphate (P'-5') Adenosine" 100.00 124 100.00 100.00 1.53e-85 PDB 1JS0 "Crystal Structure Of 3d Domain-Swapped Rnase A Minor Trimer" 100.00 124 100.00 100.00 1.53e-85 PDB 1JVT "Crystal Structure Of Ribonuclease A (Ligand-Free Form)" 100.00 124 100.00 100.00 1.53e-85 PDB 1JVU "Crystal Structure Of Ribonuclease A (Complexed Form)" 100.00 124 100.00 100.00 1.53e-85 PDB 1JVV "Crystal Structure Of Ribonuclease A (Retro-Soaked Form)" 100.00 124 100.00 100.00 1.53e-85 PDB 1KF2 "Atomic Resolution Structure Of Rnase A At Ph 5.2" 100.00 124 100.00 100.00 1.53e-85 PDB 1KF3 "Atomic Resolution Structure Of Rnase A At Ph 5.9" 100.00 124 100.00 100.00 1.53e-85 PDB 1KF4 "Atomic Resolution Structure Of Rnase A At Ph 6.3" 100.00 124 100.00 100.00 1.53e-85 PDB 1KF5 "Atomic Resolution Structure Of Rnase A At Ph 7.1" 100.00 124 100.00 100.00 1.53e-85 PDB 1KF7 "Atomic Resolution Structure Of Rnase A At Ph 8.0" 100.00 124 100.00 100.00 1.53e-85 PDB 1KF8 "Atomic Resolution Structure Of Rnase A At Ph 8.8" 100.00 124 100.00 100.00 1.53e-85 PDB 1KH8 "Structure Of A Cis-Proline (P114) To Glycine Variant Of Ribonuclease A" 100.00 125 99.19 99.19 2.38e-84 PDB 1LSQ "Ribonuclease A With Asn 67 Replaced By A Beta-Aspartyl Residue" 100.00 124 99.19 99.19 1.45e-84 PDB 1O0F "Rnase A In Complex With 3',5'-Adp" 100.00 124 100.00 100.00 1.53e-85 PDB 1O0H "Ribonuclease A In Complex With 5'-Adp" 100.00 124 100.00 100.00 1.53e-85 PDB 1O0M "Ribonuclease A In Complex With Uridine-2'-Phosphate" 100.00 124 100.00 100.00 1.53e-85 PDB 1O0N "Ribonuclease A In Complex With Uridine-3'-phosphate" 100.00 124 100.00 100.00 1.53e-85 PDB 1O0O "Ribonuclease A In Complex With Adenosine-2',5'-Diphosphate" 100.00 124 100.00 100.00 1.53e-85 PDB 1QHC "Crystal Structure Of Ribonuclease A In Complex With 5'- Phospho-2'-Deoxyuridine-3'-Pyrophosphate Adenosine-3'- Phosphate" 100.00 124 100.00 100.00 1.53e-85 PDB 1RAR "Crystal Structure Of A Fluorescent Derivative Of Rnase A" 99.19 123 100.00 100.00 8.80e-85 PDB 1RAS "Crystal Structure Of A Fluorescent Derivative Of Rnase A" 99.19 123 100.00 100.00 8.80e-85 PDB 1RAT "Effects Of Temperature On Protein Structure And Dynamics: X- Ray Crystallographic Studies Of The Protein Ribonuclease-A At Nine" 100.00 124 100.00 100.00 1.53e-85 PDB 1RBB "The Crystal Structure Of Ribonuclease B At 2.5-Angstroms Resolution" 100.00 124 100.00 100.00 1.53e-85 PDB 1RBC "Crystallographic Structures Of Ribonuclease S Variants With Nonpolar Substitution At Position 13: Packing And Cavities" 83.87 104 100.00 100.00 3.09e-70 PDB 1RBD "Crystallographic Structures Of Ribonuclease S Variants With Nonpolar Substitution At Position 13: Packing And Cavities" 83.87 104 100.00 100.00 3.09e-70 PDB 1RBE "Crystallographic Structures Of Ribonuclease S Variants With Nonpolar Substitution At Position 13: Packing And Cavities" 83.87 104 100.00 100.00 3.09e-70 PDB 1RBF "Crystallographic Structures Of Ribonuclease S Variants With Nonpolar Substitution At Position 13: Packing And Cavities" 83.87 104 100.00 100.00 3.09e-70 PDB 1RBG "Crystallographic Structures Of Ribonuclease S Variants With Nonpolar Substitution At Position 13: Packing And Cavities" 83.87 104 100.00 100.00 3.09e-70 PDB 1RBH "Crystallographic Structures Of Ribonuclease S Variants With Nonpolar Substitution At Position 13: Packing And Cavities" 83.87 104 100.00 100.00 3.09e-70 PDB 1RBI "Crystallographic Structures Of Ribonuclease S Variants With Nonpolar Substitution At Position 13: Packing And Cavities" 83.87 104 100.00 100.00 3.09e-70 PDB 1RBJ "Ribonuclease B Complex With D(Tetra-(Deoxy-Adenylate))" 100.00 124 100.00 100.00 1.53e-85 PDB 1RBN "The Structure Of Ribonuclease A Derivative Ii At 2.1 Angstroms Resolution" 100.00 124 100.00 100.00 1.53e-85 PDB 1RBW "Ribonuclease A (E.C.3.1.27.5) With Guanidinium" 100.00 124 100.00 100.00 1.53e-85 PDB 1RBX "Ribonuclease A (E.C.3.1.27.5) Control" 100.00 124 100.00 100.00 1.53e-85 PDB 1RCA "Structure Of The Crystalline Complex Of Deoxycytidylyl-3', 5'-Guanosine (3',5'-Dcpdg) Co-Crystalised With Ribonuclease At 1.9 A" 100.00 124 100.00 100.00 1.53e-85 PDB 1RCN "Crystal Structure Of The Ribonuclease A D(Aptpapapg) Complex : Direct Evidence For Extended Substrate Recognition" 100.00 124 100.00 100.00 1.53e-85 PDB 1RHA "Water Dependent Domain Motion And Flexibility In Ribonuclease A And The Invariant Features In Its Hydration Shell. An X-Ray Stu" 100.00 124 100.00 100.00 1.53e-85 PDB 1RHB "Water Dependent Domain Motion And Flexibility In Ribonuclease A And The Invariant Features In Its Hydration Shell. An X-Ray Stu" 100.00 124 100.00 100.00 1.53e-85 PDB 1RNC "Newly Observed Binding Mode In Pancreatic Ribonuclease" 100.00 124 100.00 100.00 1.53e-85 PDB 1RND "Newly Observed Binding Mode In Pancreatic Ribonuclease" 100.00 124 100.00 100.00 1.53e-85 PDB 1RNM "Ribonuclease A Complex With Cytidylic Acid (5'cmp) Crystallized From 80% Ammonium Sulphate" 100.00 124 100.00 100.00 1.53e-85 PDB 1RNN "Ribonuclease A Complex With Cytidylic Acid (5'cmp) Crystallized From 8m Sodium Formate" 100.00 124 100.00 100.00 1.53e-85 PDB 1RNO "Ribonuclease A Crystallized From 80% Ammonium Sulphate" 100.00 124 100.00 100.00 1.53e-85 PDB 1RNQ "Ribonuclease A Crystallized From 8m Sodium Formate" 100.00 124 100.00 100.00 1.53e-85 PDB 1RNU "Refinement Of The Crystal Structure Of Ribonuclease S. Comparison With And Between The Various Ribonuclease A Structures" 100.00 124 100.00 100.00 1.53e-85 PDB 1RNV "Refinement Of The Crystal Structure Of Ribonuclease S. Comparison With And Between The Various Ribonuclease A Structures" 100.00 124 100.00 100.00 1.53e-85 PDB 1RNW "Recombinant Ribonuclease A Crystallized From 80% Ammonium Sulphate" 100.00 124 100.00 100.00 1.53e-85 PDB 1RNX "Ribonuclease A Crystallized From 3m Sodium Chloride, 30% Ammonium Sulfate" 100.00 124 100.00 100.00 1.53e-85 PDB 1RNY "Ribonuclease A Crystallized From 3m Cesium Chloride, 30% Ammonium Sulfate" 100.00 124 100.00 100.00 1.53e-85 PDB 1RNZ "Ribonuclease A Crystallized From 2.5m Sodium Chloride, 3.3m Sodium Formate" 100.00 124 100.00 100.00 1.53e-85 PDB 1ROB "Structure Of The Crystalline Complex Of Cytidylic Acid (2'- Cmp) With Ribonuclease At 1.6 Angstroms Resolution" 100.00 124 100.00 100.00 1.53e-85 PDB 1RPF "The Structures Of Rnase Complexed With 3'-Cmp And D(Cpa): Active Site Conformation And Conserved Water Molecules" 100.00 124 100.00 100.00 1.53e-85 PDB 1RPG "Structures Of Rnase A Complexed With 3'-Cmp And D(Cpa): Active Site Conformation And Conserved Water Molecules" 100.00 124 100.00 100.00 1.53e-85 PDB 1RPH "Structures Of Rnase A Complexed With 3'-Cmp And D(Cpa): Active Site Conformation And Conserved Water Molecules" 100.00 124 100.00 100.00 1.53e-85 PDB 1RSM "The 2-Angstroms Resolution Structure Of A Thermostable Ribonuclease A Chemically Cross-Linked Between Lysine Residues 7 And 41" 100.00 124 100.00 100.00 1.53e-85 PDB 1RTA "Crystal Structure Disposition Of Thymidylic Acid Tetramer In Complex With Ribonuclease A" 100.00 124 100.00 100.00 1.53e-85 PDB 1RTB "Crystal Structure Disposition Of Thymidylic Acid Tetramer In Complex With Ribonuclease A" 100.00 124 100.00 100.00 1.53e-85 PDB 1RUV "Ribonuclease A-Uridine Vanadate Complex: High Resolution Resolution X-Ray Structure (1.3 A)" 100.00 124 100.00 100.00 1.53e-85 PDB 1SRN "The Refined Crystal Structure Of A Fully Active Semisynthetic Ribonuclease At 1.8 Angstroms Resolution" 95.16 118 100.00 100.00 1.62e-80 PDB 1SSA "A Structural Investigation Of Catalytically Modified F12ol And F12oy Semisynthetic Ribonucleases" 95.16 118 100.00 100.00 1.62e-80 PDB 1SSB "A Structural Investigation Of Catalytically Modified F12ol And F12oy Semisynthetic Ribonucleases" 95.16 118 100.00 100.00 1.62e-80 PDB 1SSC "The 1.6 Angstroms Structure Of A Semisynthetic Ribonuclease Crystallized From Aqueous Ethanol. Comparison With Crystals From Sa" 90.32 112 100.00 100.00 2.84e-75 PDB 1U1B "Structure Of Bovine Pancreatic Ribonuclease A In Complex With 3'-phosphothymidine (3'-5')-pyrophosphate Adenosine 3'-phosphate" 100.00 124 100.00 100.00 1.53e-85 PDB 1W4O "Binding Of Nonnatural 3'-Nucleotides To Ribonuclease A" 100.00 124 100.00 100.00 1.53e-85 PDB 1W4P "Binding Of Nonnatural 3'-Nucleotides To Ribonuclease A" 100.00 124 100.00 100.00 1.53e-85 PDB 1W4Q "Binding Of Nonnatural 3'-Nucleotides To Ribonuclease A" 100.00 124 100.00 100.00 1.53e-85 PDB 1WBU "Fragment Based Lead Discovery Using Crystallography" 100.00 124 100.00 100.00 1.53e-85 PDB 1XPS "Bovine Ribonuclease A (Phosphate-Free) (93 % Humidity)" 100.00 124 100.00 100.00 1.53e-85 PDB 1XPT "Bovine Ribonuclease A (Phosphate-Free)" 100.00 124 100.00 100.00 1.53e-85 PDB 1YMN "The Study Of Reductive Unfolding Pathways Of Rnase A (Y92l Mutant)" 100.00 124 99.19 99.19 1.21e-84 PDB 1YMR "The Study Of Reductive Unfolding Pathways Of Rnase A (Y92a Mutant)" 100.00 124 99.19 99.19 2.46e-84 PDB 1YMW "The Study Of Reductive Unfolding Pathways Of Rnase A (Y92g Mutant)" 100.00 124 99.19 99.19 3.52e-84 PDB 1Z3L "X-Ray Crystal Structure Of A Mutant Ribonuclease S (F8anb)" 83.87 104 100.00 100.00 3.09e-70 PDB 1Z3M "Crystal Structure Of Mutant Ribonuclease S (F8nva)" 83.87 104 100.00 100.00 3.09e-70 PDB 1Z3P "X-Ray Crystal Structure Of A Mutant Ribonuclease S (M13nva)" 83.87 104 100.00 100.00 3.09e-70 PDB 1Z6D "Ribonuclease A- Imp Complex" 100.00 124 100.00 100.00 1.53e-85 PDB 1Z6S "Ribonuclease A- Amp Complex" 100.00 124 100.00 100.00 1.53e-85 PDB 2AAS "High-Resolution Three-Dimensional Structure Of Ribonuclease A In Solution By Nuclear Magnetic Resonance Spectroscopy" 100.00 124 100.00 100.00 1.53e-85 PDB 2BLP "Rnase Before Unattenuated X-Ray Burn" 100.00 124 100.00 100.00 1.53e-85 PDB 2BLZ 'Rnase After A High Dose X-Ray "burn"' 100.00 124 100.00 100.00 1.53e-85 PDB 2E33 "Structural Basis For Selection Of Glycosylated Substrate By Scffbs1 Ubiquitin Ligase" 100.00 124 100.00 100.00 1.53e-85 PDB 2E3W "X-Ray Structure Of Native Rnase A" 100.00 124 100.00 100.00 1.53e-85 PDB 2G4W "Anomalous Substructure Of Ribonuclease A (c2)" 100.00 124 100.00 100.00 1.53e-85 PDB 2G4X "Anomalous Substructure Od Ribonuclease A (P3221)" 100.00 124 100.00 100.00 1.53e-85 PDB 2G8Q "The Crystal Structure Of Rnase A From Monoclinic Crystals At 100 K" 100.00 124 100.00 100.00 1.53e-85 PDB 2G8R "The Crystal Structure Of The Rnase A- 3-N-Piperidine-4- Carboxyl-3-Deoxy-Ara-Uridine Complex" 100.00 124 100.00 100.00 1.53e-85 PDB 2NUI "X-Ray Structure Of Synthetic [d83a]rnase A" 100.00 124 99.19 99.19 2.65e-84 PDB 2OP2 "Crystal Structure Of Rnase Double-Mutant V43c R85c With Extra Disulphide Bond" 100.00 124 98.39 98.39 8.72e-83 PDB 2OQF "Structure Of A Synthetic, Non-Natural Analogue Of Rnase A: [n71k(Ade), D83a]rnase A" 100.00 124 98.39 98.39 2.20e-83 PDB 2P42 "Complex Of A Camelid Single-Domain Vhh Antibody Fragment With Rnase A At 1.8a Resolution: Se3-Mono-2 Crystal Form With Three Se" 100.00 124 100.00 100.00 1.53e-85 PDB 2P43 "Complex Of A Camelid Single-Domain Vhh Antibody Fragment With Rnase A At 1.65a Resolution: Se3-Mono-1 Crystal Form With Three S" 100.00 124 100.00 100.00 1.53e-85 PDB 2P44 "Complex Of A Camelid Single-Domain Vhh Antibody Fragment With Rnase A At 1.8a Resolution: Se5a-Mono-1 Crystal Form With Five Se" 100.00 124 100.00 100.00 1.53e-85 PDB 2P45 "Complex Of A Camelid Single-domain Vhh Antibody Fragment With Rnase A At 1.1a Resolution: Se5b-ortho-1 Crystal Form With Five S" 100.00 124 100.00 100.00 1.53e-85 PDB 2P46 "Complex Of A Camelid Single-Domain Vhh Antibody Fragment With Rnase A At 2.5a Resolution: Se5b-Ortho-2 Crystal Form With Five S" 100.00 124 100.00 100.00 1.53e-85 PDB 2P47 "Complex Of A Camelid Single-Domain Vhh Antibody Fragment With Rnase A At 2.5a Resolution: Se5b-Tri Crystal Form With Five Se-Me" 100.00 124 100.00 100.00 1.53e-85 PDB 2P48 "Complex Of A Camelid Single-Domain Vhh Antibody Fragment With Rnase A At 2.3a Resolution: Se5b-Tetra Crystal Form With Five Se-" 100.00 124 100.00 100.00 1.53e-85 PDB 2P49 "Complex Of A Camelid Single-Domain Vhh Antibody Fragment With Rnase A At 1.4a Resolution: Native Mono_1 Crystal Form" 100.00 124 100.00 100.00 1.53e-85 PDB 2P4A "X-Ray Structure Of A Camelid Affinity Matured Single-Domain Vhh Antibody Fragment In Complex With Rnase A" 100.00 124 100.00 100.00 1.53e-85 PDB 2QCA "A New Crystal Form Of Bovine Pancreatic Rnase A In Complex With 2'- Deoxyguanosine-5'-Monophosphate" 100.00 124 100.00 100.00 1.53e-85 PDB 2RAT "Effects Of Temperature On Protein Structure And Dynamics: X- Ray Crystallographic Studies Of The Protein Ribonuclease-A At Nine" 100.00 124 100.00 100.00 1.53e-85 PDB 2RLN "Thermodynamic And Structural Consequences Of Changing A Sulphur Atom To A Methylene Group In The M13nle Mutation In Ribonucleas" 87.90 109 100.00 100.00 2.34e-73 PDB 2RNS "Refinement Of The Crystal Structure Of Ribonuclease S. Comparison With And Between The Various Ribonuclease A Structures" 100.00 124 100.00 100.00 1.53e-85 PDB 2W5G "Rnase A-5'-Atp Complex" 100.00 124 100.00 100.00 1.53e-85 PDB 2W5I "Rnase A-Ap3a Complex" 100.00 124 100.00 100.00 1.53e-85 PDB 2W5K "Rnase A-Nadph Complex" 100.00 124 100.00 100.00 1.53e-85 PDB 2W5L "Rnase A-Nadp Complex" 100.00 124 100.00 100.00 1.53e-85 PDB 2W5M "Rnase A-Pyrophosphate Ion Complex" 100.00 124 100.00 100.00 1.53e-85 PDB 2XOG "Functional And Structural Analyses Of N-Acylsulfonamide- Linked Dinucleoside Inhibitors Of Ribonuclease A" 100.00 124 100.00 100.00 1.53e-85 PDB 2XOI "Functional And Structural Analyses Of N-Acylsulfonamide- Linked Dinucleoside Inhibitors Of Ribonuclease A" 100.00 124 100.00 100.00 1.53e-85 PDB 3A1R "Neutron Crystal Structure Analysis Of Bovine Pancreatic Ribonuclease A" 100.00 124 100.00 100.00 1.53e-85 PDB 3D6O "The Rnase A- 5'-Deoxy-5'-N-(Ethyl Isonipecotatyl)uridine Complex" 100.00 124 100.00 100.00 1.53e-85 PDB 3D6P "Rnase A- 5'-Deoxy-5'-N-Morpholinouridine Complex" 100.00 124 100.00 100.00 1.53e-85 PDB 3D6Q "The Rnase A- 5'-Deoxy-5'-N-Piperidinouridine Complex" 100.00 124 100.00 100.00 1.53e-85 PDB 3D7B "The Ribonuclease A- 5'-Deoxy-5'-N-Pyrrolidinouridine Complex" 100.00 124 100.00 100.00 1.53e-85 PDB 3D8Y "Rnase A- 5'-deoxy-5'-n-piperidinothymidine Complex" 100.00 124 100.00 100.00 1.53e-85 PDB 3D8Z "Rnase A- 5'-deoxy-5'-n-pyrrolidinothymidine Complex" 100.00 124 100.00 100.00 1.53e-85 PDB 3DH5 "Crystal Structure Of Bovine Pancreatic Ribonuclease A (Wild- Type)" 100.00 124 100.00 100.00 1.53e-85 PDB 3DH6 "Crystal Structure Of Bovine Pancreatic Ribonuclease A Variant (V47a)" 100.00 124 99.19 99.19 7.97e-85 PDB 3DI7 "Crystal Structure Of Bovine Pancreatic Ribonuclease A Variant (V54a)" 100.00 124 99.19 99.19 7.97e-85 PDB 3DI8 "Crystal Structure Of Bovine Pancreatic Ribonuclease A Variant (V57a)" 100.00 124 99.19 99.19 7.97e-85 PDB 3DI9 "Crystal Structure Of Bovine Pancreatic Ribonuclease A Variant (I81a)" 100.00 124 99.19 99.19 1.41e-84 PDB 3DIB "Crystal Structure Of Bovine Pancreatic Ribonuclease A Variant (I106a)" 100.00 124 99.19 99.19 1.41e-84 PDB 3DIC "Crystal Structure Of Bovine Pancreatic Ribonuclease A Variant (V108a)" 100.00 124 99.19 99.19 7.97e-85 PDB 3DXG "Ribonuclease A- Uridine 5' Phosphate Complex" 100.00 124 100.00 100.00 1.53e-85 PDB 3DXH "Ribonuclease A Uridine 5' Diphosphate Complex" 100.00 124 100.00 100.00 1.53e-85 PDB 3EUX "Crystal Structure Of Crosslinked Ribonuclease A" 100.00 124 100.00 100.00 1.53e-85 PDB 3EUY "Crystal Structure Of Ribonuclease A In 50% Dioxane" 100.00 124 100.00 100.00 1.53e-85 PDB 3EUZ "Crystal Structure Of Ribonuclease A In 50% Dimethylformamide" 100.00 124 100.00 100.00 1.53e-85 PDB 3EV0 "Crystal Structure Of Ribonuclease A In 70% Dimethyl Sulfoxide" 100.00 124 100.00 100.00 1.53e-85 PDB 3EV1 "Crystal Structure Of Ribonuclease A In 70% Hexanediol" 100.00 124 100.00 100.00 1.53e-85 PDB 3EV2 "Crystal Structure Of Ribonuclease A In 70% Isopropanol" 100.00 124 100.00 100.00 1.53e-85 PDB 3EV3 "Crystal Structure Of Ribonuclease A In 70% T-Butanol" 100.00 124 100.00 100.00 1.53e-85 PDB 3EV4 "Crystal Structure Of Ribonuclease A In 50% Trifluoroethanol" 100.00 124 100.00 100.00 1.53e-85 PDB 3EV5 "Crystal Structure Of Ribonuclease A In 1m Trimethylamine N-Oxide" 100.00 124 100.00 100.00 1.53e-85 PDB 3EV6 "Crystal Structure Of Ribonuclease A In 50% R,S,R-Bisfuranol" 100.00 124 100.00 100.00 1.53e-85 PDB 3FL0 "X-Ray Structure Of The Non Covalent Swapped Form Of The Q28lK31CS32C MUTANT OF BOVINE PANCREATIC RIBONUCLEASE IN Complex With 2" 100.00 124 97.58 97.58 5.11e-83 PDB 3I67 "Ribonuclease A By Lb Nanotemplate Method After High X-Ray Dose On Esrf Id14-2 Beamline" 100.00 124 100.00 100.00 1.53e-85 PDB 3I6F "Ribonuclease A By Classical Hanging Drop Method Before High X-Ray Dose On Esrf Id14-2 Beamline" 100.00 124 100.00 100.00 1.53e-85 PDB 3I6H "Ribonuclease A By Lb Nanotemplate Method Before High X-Ray Dose On Esrf Id14-2 Beamline" 100.00 124 100.00 100.00 1.53e-85 PDB 3I6J "Ribonuclease A By Classical Hanging Drop Method After High X-Ray Dose On Esrf Id14-2 Beamline" 100.00 124 100.00 100.00 1.53e-85 PDB 3I7W "High Pressure Structure Of Wild-Type Rnase A (0.67 Gpa)" 100.00 124 100.00 100.00 1.53e-85 PDB 3I7X "High Pressure Structure Of I106a Rnase A Variant (0.35 Gpa)" 100.00 124 99.19 99.19 1.41e-84 PDB 3I7Y "High Pressure Structure Of I106a Variant Of Rnase A (0.48 Gpa)" 100.00 124 99.19 99.19 1.41e-84 PDB 3JW1 "Crystal Structure Of Bovine Pancreatic Ribonuclease Complexed With Uridine-5'-monophosphate At 1.60 A Resolution" 100.00 124 100.00 100.00 1.53e-85 PDB 3LXO "The Crystal Structure Of Ribonuclease A In Complex With Thymidine-3'- Monophosphate" 100.00 124 100.00 100.00 1.53e-85 PDB 3MWQ "Crystal Structure Of Ribonuclease A Tandem Enzymes And Their Interaction With The Cytosolic Ribonuclease Inhibitor" 100.00 256 100.00 100.00 1.05e-83 PDB 3MWR "Crystal Structure Of Ribonuclease A Tandem Enzymes And Their Interaction With The Cytosolic Ribonuclease Inhibitor" 100.00 254 100.00 100.00 9.05e-84 PDB 3MX8 "Crystal Structure Of Ribonuclease A Tandem Enzymes And Their Interaction With The Cytosolic Ribonuclease Inhibitor" 100.00 252 100.00 100.00 1.33e-83 PDB 3MZQ "Rnase Crystals Grown By The Hanging Drop Method" 100.00 128 100.00 100.00 1.48e-85 PDB 3MZR "Rnase Crystals Grown In Loops/micromounts" 100.00 128 100.00 100.00 1.48e-85 PDB 3OQY "Semi-Synthetic Ribonuclease S: Para-Cyano-Phenylalanine At Position 8" 83.87 104 100.00 100.00 3.09e-70 PDB 3OQZ "Semi-Synthetic Ribonuclease S: Meta-Cyano-Phenylalanine At Position 8" 83.87 104 100.00 100.00 3.09e-70 PDB 3OR0 "Semi-Synthetic Ribonuclease S: Cyanylated Homocysteine At Position 13" 83.87 104 100.00 100.00 3.09e-70 PDB 3QL1 "Crystal Structure Of Ribonuclease A Variant A4c/d83e/v118c" 100.00 124 97.58 98.39 7.17e-83 PDB 3QL2 "Crystal Structure Of Ribonuclease A Variant A4c/d83e/v118c" 100.00 124 97.58 98.39 7.17e-83 PDB 3QSK "5 Histidine Variant Of The Anti-Rnase A Vhh In Complex With Rnase A" 100.00 124 100.00 100.00 1.53e-85 PDB 3RAT "Effects Of Temperature On Protein Structure And Dynamics: X- Ray Crystallographic Studies Of The Protein Ribonuclease-A At Nine" 100.00 124 100.00 100.00 1.53e-85 PDB 3RH1 "X-ray Structure Of A Cis-proline (p114) To Alanine Variant Of Ribonuclease A" 100.00 124 99.19 99.19 1.69e-84 PDB 3RID "X-ray Structure Of The C-terminal Swapped Dimer Of P114a Variant Of Ribonuclease A" 100.00 124 99.19 99.19 1.69e-84 PDB 3RN3 "Segmented Anisotropic Refinement Of Bovine Ribonuclease A By The Application Of The Rigid-Body Tls Model" 100.00 124 100.00 100.00 1.53e-85 PDB 3RSD "Structure Of The D121n Variant Of Ribonuclease A" 100.00 124 99.19 100.00 9.19e-85 PDB 3RSK "Structure Of The K7aR10AK66A VARIANT OF RIBONUCLEASE A" 100.00 124 97.58 97.58 9.02e-83 PDB 3RSP "Structure Of The P93g Variant Of Ribonuclease A" 100.00 124 99.19 99.19 2.54e-84 PDB 3SRN "Structural Changes That Accompany The Reduced Catalytic Efficiency Of Two Semisynthetic Ribonuclease Analogs" 91.13 113 100.00 100.00 5.29e-76 PDB 4AO1 "High Resolution Crystal Structure Of Bovine Pancreatic Ribonuclease Crystallized Using Ionic Liquid" 100.00 124 100.00 100.00 1.53e-85 PDB 4G8V "Crystal Structure Of Ribonuclease A In Complex With 5a" 100.00 124 100.00 100.00 1.53e-85 PDB 4G8Y "Crystal Structure Of Ribonuclease A In Complex With 5b" 100.00 124 100.00 100.00 1.53e-85 PDB 4G90 "Crystal Structure Of Ribonuclease A In Complex With 5e" 100.00 124 100.00 100.00 1.53e-85 PDB 4J5Z "Crystal Structure Of Ribonuclease A In Aqueous Solution: One Of Twelve In Mscs Set" 100.00 124 100.00 100.00 1.53e-85 PDB 4J60 "Crystal Structure Of Ribonuclease A Soaked In 25% Cyclopentanol: One Of Twelve In Mscs Set" 100.00 124 100.00 100.00 1.53e-85 PDB 4J61 "Crystal Structure Of Ribonuclease A Soaked In 40% Cyclopentanone: One Of Twelve In Mscs Set" 100.00 124 100.00 100.00 1.53e-85 PDB 4J62 "Crystal Structure Of Ribonuclease A Soaked In 40% Cyclohexanol: One Of Twelve In Mscs Set" 100.00 124 100.00 100.00 1.53e-85 PDB 4J63 "Crystal Structure Of Ribonuclease A Soaked In 40% Cyclohexanone: One Of Twelve In Mscs Set" 100.00 124 100.00 100.00 1.53e-85 PDB 4J64 "Crystal Structure Of Ribonuclease A Soaked In 40% Dioxane: One Of Twelve In Mscs Set" 100.00 124 100.00 100.00 1.53e-85 PDB 4J65 "Crystal Structure Of Ribonuclease A Soaked In 40% Dimethylformamide: One Of Twelve In Mscs Set" 100.00 124 100.00 100.00 1.53e-85 PDB 4J66 "Crystal Structure Of Ribonuclease A Soaked In 25% Dimethyl Sulfoxide: One Of Twelve In Mscs Set" 100.00 124 100.00 100.00 1.53e-85 PDB 4J67 "Crystal Structure Of Ribonuclease A Soaked In 50% 1,6-hexanediol: One Of Twelve In Mscs Set" 100.00 124 100.00 100.00 1.53e-85 PDB 4J68 "Crystal Structure Of Ribonuclease A Soaked In 40% Isopropanol: One Of Twelve In Mscs Set" 100.00 124 100.00 100.00 1.53e-85 PDB 4J69 "Crystal Structure Of Ribonuclease A Soaked In 50% S,r,s-bisfuranol: One Of Twelve In Mscs Set" 100.00 124 100.00 100.00 1.53e-85 PDB 4J6A "Crystal Structure Of Ribonuclease A Soaked In 40% 2,2,2- Trifluoroethanol: One Of Twelve In Mscs Set" 100.00 124 100.00 100.00 1.53e-85 PDB 4K7L "Crystal Structure Of Rnase S Variant (k7c/q11c)" 83.87 104 100.00 100.00 3.09e-70 PDB 4L55 "X-ray Structure Of The Adduct Between Bovine Pancreatic Ribonuclease And Aziru" 100.00 124 100.00 100.00 1.53e-85 PDB 4MXF "X-ray Structure Of The Adduct Between Bovine Pancreatic Ribonuclease And Auoxo6, A Dinuclear Gold(iii) Complex With -dioxo Brid" 100.00 124 100.00 100.00 1.53e-85 PDB 4O36 "Semisynthetic Rnase S1-15-h7/11-q10" 83.87 104 100.00 100.00 3.09e-70 PDB 4O37 "Seminsynthetic Rnase S1-15-3pl-7/11" 83.87 104 100.00 100.00 3.09e-70 PDB 4OKF "Rnase S In Complex With An Artificial Peptide" 83.87 104 100.00 100.00 3.09e-70 PDB 4OOH "Structure Of Ribonuclease A At 40c" 100.00 124 100.00 100.00 1.53e-85 PDB 4OT4 "X-ray Structure Of The Adduct Formed Between Cisplatin And Ribonuclease A" 100.00 124 100.00 100.00 1.53e-85 PDB 4PEQ "Structure Of Bovine Ribonuclease Inhibitor Complexed With Bovine Ribonuclease I" 100.00 124 100.00 100.00 1.53e-85 PDB 4POU "Vhh-metal In Complex With Rnase A" 100.00 124 100.00 100.00 1.53e-85 PDB 4QH3 "X-ray Structure Of The Adduct Formed Between Bovine Pancreatic Ribonuclease And Trans-dimethylamine Methylamine Dichlorido Plat" 100.00 124 100.00 100.00 1.53e-85 PDB 4RAT "Effects Of Temperature On Protein Structure And Dynamics: X- Ray Crystallographic Studies Of The Protein Ribonuclease-A At Nine" 100.00 124 100.00 100.00 1.53e-85 PDB 4RSD "Structure Of The D121a Variant Of Ribonuclease A" 100.00 124 99.19 99.19 2.65e-84 PDB 4RSK "Structure Of The K7aR10AK66A VARIANT OF RIBONUCLEASE A Complexed With 3'-Ump" 100.00 124 97.58 97.58 9.02e-83 PDB 4RTE "The X-ray Structure Of Bovine Pancreatic Ribonuclease Incubated In The Presence Of An Excess Of Cisplatin (1:10 Ratio)" 100.00 124 100.00 100.00 1.53e-85 PDB 4SRN "Structural Changes That Accompany The Reduced Catalytic Efficiency Of Two Semisynthetic Ribonuclease Analogs" 91.13 113 100.00 100.00 5.29e-76 PDB 4YGW "Rnase S In Complex With Stabilized S Peptide" 83.06 103 100.00 100.00 9.84e-70 PDB 5RAT "Effects Of Temperature On Protein Structure And Dynamics: X- Ray Crystallographic Studies Of The Protein Ribonuclease-A At Nine" 100.00 124 100.00 100.00 1.53e-85 PDB 5RSA "Comparison Of Two Independently Refined Models Of Ribonuclease-A" 99.19 124 100.00 100.00 9.09e-85 PDB 6RAT "Effects Of Temperature On Protein Structure And Dynamics: X-Ray Crystallographic Studies Of The Protein Ribonuclease-A At Nine " 100.00 124 100.00 100.00 1.53e-85 PDB 6RSA "Nuclear Magnetic Resonance And Neutron Diffraction Studies Of The Complex Of RibonucleaseA With Uridine Vanadate, A Transition-" 100.00 124 100.00 100.00 1.53e-85 PDB 7RAT "Effects Of Temperature On Protein Structure And Dynamics: X- Ray Crystallographic Studies Of The Protein Ribonuclease-A At Nine" 100.00 124 100.00 100.00 1.53e-85 PDB 7RSA "Structure Of Phosphate-Free Ribonuclease A Refined At 1.26 Angstroms" 100.00 124 100.00 100.00 1.53e-85 PDB 8RAT "Effects Of Temperature On Protein Structure And Dynamics: X- Ray Crystallographic Studies Of The Protein Ribonuclease-A At Nine" 100.00 124 100.00 100.00 1.53e-85 PDB 8RSA "Crystal Structure Of Two Covalent Nucleoside Derivatives Of Ribonuclease A" 100.00 124 100.00 100.00 1.53e-85 PDB 9RAT "Effects Of Temperature On Protein Structure And Dynamics: X-Ray Crystallographic Studies Of The Protein Ribonuclease-A At Nine " 100.00 124 100.00 100.00 1.53e-85 PDB 9RSA "Crystal Structure Of Two Covalent Nucleoside Derivatives Of Ribonuclease A" 100.00 124 100.00 100.00 1.53e-85 EMBL CAA30263 "ribonuclease [Bos taurus]" 100.00 150 100.00 100.00 1.57e-86 EMBL CAA33801 "unnamed protein product [Bos taurus]" 100.00 125 100.00 100.00 1.50e-85 EMBL CAB37066 "artificial [synthetic construct]" 100.00 128 100.00 100.00 1.58e-85 GB AAA72269 "ribonuclease S [synthetic construct]" 83.87 105 100.00 100.00 2.56e-70 GB AAA72757 "RNase A [synthetic construct]" 100.00 156 100.00 100.00 2.74e-86 GB AAB35594 "ribonuclease A, partial [Bos taurus]" 100.00 128 100.00 100.00 1.48e-85 GB AAB36134 "pancreatic-type ribonuclease, partial [Bos taurus]" 100.00 124 100.00 100.00 1.53e-85 GB AAI49530 "RNASE1 protein [Bos taurus]" 100.00 150 100.00 100.00 1.57e-86 PIR JC5560 "pancreatic ribonuclease (EC 3.1.27.5) A - Aspergillus niger var. macrosporus" 100.00 124 100.00 100.00 1.53e-85 PIR NRBOB "pancreatic ribonuclease (EC 3.1.27.5) - American bison (tentative sequence)" 100.00 124 100.00 100.00 1.53e-85 PRF 630436A RNase 100.00 124 100.00 100.00 1.53e-85 REF NP_001014408 "ribonuclease pancreatic precursor [Bos taurus]" 100.00 150 100.00 100.00 1.57e-86 REF XP_005211519 "PREDICTED: ribonuclease pancreatic isoform X1 [Bos taurus]" 100.00 150 100.00 100.00 1.57e-86 REF XP_005901936 "PREDICTED: ribonuclease pancreatic [Bos mutus]" 100.00 150 99.19 100.00 5.37e-86 REF XP_010837737 "PREDICTED: ribonuclease pancreatic [Bison bison bison]" 100.00 150 100.00 100.00 1.57e-86 SP P61823 "RecName: Full=Ribonuclease pancreatic; AltName: Full=RNase 1; AltName: Full=RNase A; Flags: Precursor" 100.00 150 100.00 100.00 1.57e-86 SP P61824 "RecName: Full=Ribonuclease pancreatic; AltName: Full=RNase 1; AltName: Full=RNase A" 100.00 124 100.00 100.00 1.53e-85 TPE CDG32088 "TPA: ribonuclease A C2 [Bos taurus]" 100.00 215 100.00 100.00 1.96e-86 TPG DAA25470 "TPA: ribonuclease pancreatic precursor [Bos taurus]" 100.00 150 100.00 100.00 1.57e-86 stop_ save_ #################### # Natural source # #################### save_natural_source _Saveframe_category natural_source loop_ _Mol_label _Organism_name_common _NCBI_taxonomy_ID _Superkingdom _Kingdom _Genus _Species _Details $ribonuclease_A Cow 9913 Eukaryota Metazoa Bos taurus 'tissue: pancreas' stop_ save_ ######################### # Experimental source # ######################### save_experimental_source _Saveframe_category experimental_source loop_ _Mol_label _Production_method _Host_organism_name_common _Genus _Species _Strain _Vector_name $ribonuclease_A 'recombinant technology' . Escherichia coli . 'PET-22b (+)' stop_ save_ ##################################### # Sample contents and methodology # ##################################### ######################## # Sample description # ######################## save_sample_1 _Saveframe_category sample _Sample_type solution _Details . loop_ _Mol_label _Concentration_value _Concentration_value_units _Isotopic_labeling $ribonuclease_A 1.75 mM '[U-98% 13C; U-98% 15N]' H2O 90 % 'natural abundance' D2O 10 % 'natural abundance' urea 8 M 'natural abundance' stop_ save_ ############################ # Computer software used # ############################ save_SPARKY _Saveframe_category software _Name SPARKY _Version . loop_ _Vendor _Address _Electronic_address Goddard . . stop_ loop_ _Task 'chemical shift assignment' stop_ _Details . save_ save_TOPSPIN _Saveframe_category software _Name TOPSPIN _Version . loop_ _Vendor _Address _Electronic_address 'Bruker Biospin' . . stop_ loop_ _Task processing stop_ _Details . save_ ######################### # Experimental detail # ######################### ################################## # NMR Spectrometer definitions # ################################## save_spectrometer_1 _Saveframe_category NMR_spectrometer _Manufacturer Bruker _Model 'Avance US2 NMR' _Field_strength 800 _Details . save_ ############################# # NMR applied experiments # ############################# save_2D_1H-15N_HSQC_1 _Saveframe_category NMR_applied_experiment _Experiment_name '2D 1H-15N HSQC' _Sample_label $sample_1 save_ save_2D_1H-13C_HSQC_2 _Saveframe_category NMR_applied_experiment _Experiment_name '2D 1H-13C HSQC' _Sample_label $sample_1 save_ save_2D_1H-1H_NOESY_3 _Saveframe_category NMR_applied_experiment _Experiment_name '2D 1H-1H NOESY' _Sample_label $sample_1 save_ save_3D_HNCA_4 _Saveframe_category NMR_applied_experiment _Experiment_name '3D HNCA' _Sample_label $sample_1 save_ save_3D_HNCACB_5 _Saveframe_category NMR_applied_experiment _Experiment_name '3D HNCACB' _Sample_label $sample_1 save_ save_3D_CBCA(CO)NH_6 _Saveframe_category NMR_applied_experiment _Experiment_name '3D CBCA(CO)NH' _Sample_label $sample_1 save_ save_3D_HN(CO)CA_7 _Saveframe_category NMR_applied_experiment _Experiment_name '3D HN(CO)CA' _Sample_label $sample_1 save_ save_2D_CB-edited_1H-15N_HSQC_8 _Saveframe_category NMR_applied_experiment _Experiment_name '2D CB-edited 1H-15N HSQC' _Sample_label $sample_1 save_ save_2D_CG-edited_1H-15N_HSQC_9 _Saveframe_category NMR_applied_experiment _Experiment_name '2D CG-edited 1H-15N HSQC' _Sample_label $sample_1 save_ ####################### # Sample conditions # ####################### save_sample_conditions_1 _Saveframe_category sample_conditions _Details 'urea 8M' loop_ _Variable_type _Variable_value _Variable_value_error _Variable_value_units pH 2.0 0.1 pH pressure 1 . atm temperature 298 0.1 K stop_ save_ #################### # NMR parameters # #################### ############################## # Assigned chemical shifts # ############################## ################################ # Chemical shift referencing # ################################ save_chemical_shift_reference_1 _Saveframe_category chemical_shift_reference _Details . loop_ _Mol_common_name _Atom_type _Atom_isotope_number _Atom_group _Chem_shift_units _Chem_shift_value _Reference_method _Reference_type _External_reference_sample_geometry _External_reference_location _External_reference_axis _Indirect_shift_ratio DSS C 13 'methyl protons' ppm 0.00 . indirect . . . 0.251449530 DSS H 1 'methyl protons' ppm 0.00 internal direct . . . 1.000000000 DSS N 15 'methyl protons' ppm 0.00 . indirect . . . 0.101329118 stop_ save_ ################################### # Assigned chemical shift lists # ################################### ################################################################### # Chemical Shift Ambiguity Index Value Definitions # # # # The values other than 1 are used for those atoms with different # # chemical shifts that cannot be assigned to stereospecific atoms # # or to specific residues or chains. # # # # Index Value Definition # # # # 1 Unique (including isolated methyl protons, # # geminal atoms, and geminal methyl # # groups with identical chemical shifts) # # (e.g. ILE HD11, HD12, HD13 protons) # # 2 Ambiguity of geminal atoms or geminal methyl # # proton groups (e.g. ASP HB2 and HB3 # # protons, LEU CD1 and CD2 carbons, or # # LEU HD11, HD12, HD13 and HD21, HD22, # # HD23 methyl protons) # # 3 Aromatic atoms on opposite sides of # # symmetrical rings (e.g. TYR HE1 and HE2 # # protons) # # 4 Intraresidue ambiguities (e.g. LYS HG and # # HD protons or TRP HZ2 and HZ3 protons) # # 5 Interresidue ambiguities (LYS 12 vs. LYS 27) # # 6 Intermolecular ambiguities (e.g. ASP 31 CA # # in monomer 1 and ASP 31 CA in monomer 2 # # of an asymmetrical homodimer, duplex # # DNA assignments, or other assignments # # that may apply to atoms in one or more # # molecule in the molecular assembly) # # 9 Ambiguous, specific ambiguity not defined # # # ################################################################### save_assigned_chem_shift_list_1 _Saveframe_category assigned_chemical_shifts _Details . loop_ _Software_label $SPARKY stop_ loop_ _Experiment_label '2D 1H-15N HSQC' '3D HNCA' '3D HNCACB' '3D CBCA(CO)NH' '3D HN(CO)CA' stop_ loop_ _Sample_label $sample_1 stop_ _Sample_conditions_label $sample_conditions_1 _Chem_shift_reference_set_label $chemical_shift_reference_1 _Mol_system_component_name 'ribonuclease A' _Text_data_format . _Text_data . loop_ _Atom_shift_assign_ID _Residue_author_seq_code _Residue_seq_code _Residue_label _Atom_name _Atom_type _Chem_shift_value _Chem_shift_value_error _Chem_shift_ambiguity_code 1 1 1 LYS CA C 55.89 0.01 1 2 1 1 LYS CB C 33.37 0.01 1 3 2 2 GLU H H 8.950 0.001 1 4 2 2 GLU CA C 55.87 0.01 1 5 2 2 GLU CB C 29.22 0.01 1 6 2 2 GLU N N 123.8 0.1 1 7 3 3 THR H H 8.469 0.001 1 8 3 3 THR CA C 61.81 0.01 1 9 3 3 THR CB C 70.19 0.01 1 10 3 3 THR N N 117.0 0.1 1 11 4 4 ALA H H 8.421 0.001 1 12 4 4 ALA CA C 52.51 0.01 1 13 4 4 ALA CB C 19.36 0.01 1 14 4 4 ALA N N 126.5 0.1 1 15 5 5 ALA H H 8.284 0.001 1 16 5 5 ALA CA C 52.48 0.01 1 17 5 5 ALA CB C 19.27 0.01 1 18 5 5 ALA N N 123.6 0.1 1 19 6 6 ALA H H 8.230 0.001 1 20 6 6 ALA CA C 52.54 0.01 1 21 6 6 ALA CB C 19.29 0.01 1 22 6 6 ALA N N 123.6 0.1 1 23 7 7 LYS H H 8.249 0.001 1 24 7 7 LYS CA C 56.63 0.01 1 25 7 7 LYS CB C 33.29 0.01 1 26 7 7 LYS N N 120.6 0.1 1 27 8 8 PHE H H 8.261 0.001 1 28 8 8 PHE CA C 57.63 0.01 1 29 8 8 PHE CB C 39.71 0.01 1 30 8 8 PHE N N 120.8 0.1 1 31 9 9 GLU H H 8.340 0.001 1 32 9 9 GLU CA C 55.54 0.01 1 33 9 9 GLU CB C 29.33 0.01 1 34 9 9 GLU N N 122.5 0.1 1 35 10 10 ARG H H 8.433 0.001 1 36 10 10 ARG CA C 56.40 0.01 1 37 10 10 ARG CB C 30.92 0.01 1 38 10 10 ARG N N 122.9 0.1 1 39 11 11 GLN H H 8.561 0.001 1 40 11 11 GLN CA C 56.03 0.01 1 41 11 11 GLN CB C 29.82 0.01 1 42 11 11 GLN N N 121.6 0.1 1 43 12 12 HIS H H 8.747 0.001 1 44 12 12 HIS CA C 55.45 0.01 1 45 12 12 HIS CB C 29.04 0.01 1 46 12 12 HIS N N 120.2 0.1 1 47 13 13 MET H H 8.603 0.001 1 48 13 13 MET CA C 55.52 0.01 1 49 13 13 MET CB C 33.29 0.01 1 50 13 13 MET N N 122.7 0.1 1 51 14 14 ASP H H 8.763 0.001 1 52 14 14 ASP CA C 53.05 0.01 1 53 14 14 ASP CB C 38.37 0.01 1 54 14 14 ASP N N 121.2 0.1 1 55 15 15 SER H H 8.436 0.001 1 56 15 15 SER CA C 58.49 0.01 1 57 15 15 SER CB C 64.02 0.01 1 58 15 15 SER N N 116.6 0.1 1 59 16 16 SER H H 8.370 0.001 1 60 16 16 SER CA C 58.57 0.01 1 61 16 16 SER CB C 63.95 0.01 1 62 16 16 SER N N 117.5 0.1 1 63 17 17 THR H H 8.259 0.001 1 64 17 17 THR CA C 61.85 0.01 1 65 17 17 THR CB C 69.93 0.01 1 66 17 17 THR N N 115.2 0.1 1 67 18 18 SER H H 8.328 0.001 1 68 18 18 SER CA C 58.40 0.01 1 69 18 18 SER CB C 64.06 0.01 1 70 18 18 SER N N 117.8 0.1 1 71 19 19 ALA H H 8.367 0.001 1 72 19 19 ALA CA C 52.69 0.01 1 73 19 19 ALA CB C 19.30 0.01 1 74 19 19 ALA N N 126.2 0.1 1 75 20 20 ALA H H 8.263 0.001 1 76 20 20 ALA CA C 52.01 0.01 1 77 20 20 ALA CB C 19.47 0.01 1 78 20 20 ALA N N 123.1 0.1 1 79 21 21 SER H H 8.799 0.001 1 80 21 21 SER CA C 58.45 0.01 1 81 21 21 SER CB C 64.00 0.01 1 82 21 21 SER N N 116.7 0.1 1 83 22 22 SER H H 8.477 0.001 1 84 22 22 SER CA C 58.54 0.01 1 85 22 22 SER N N 117.8 0.1 1 86 23 23 SER CA C 58.60 0.01 1 87 23 23 SER CB C 63.93 0.01 1 88 24 24 ASN H H 8.413 0.001 1 89 24 24 ASN CA C 53.33 0.01 1 90 24 24 ASN CB C 38.94 0.01 1 91 24 24 ASN N N 120.8 0.1 1 92 25 25 TYR H H 8.229 0.001 1 93 25 25 TYR CA C 59.01 0.01 1 94 25 25 TYR CB C 38.54 0.01 1 95 25 25 TYR N N 120.9 0.1 1 96 26 26 CYS H H 8.454 0.001 1 97 26 26 CYS CA C 55.59 0.01 1 98 26 26 CYS CB C 40.30 0.01 1 99 26 26 CYS N N 118.9 0.1 1 100 27 27 ASN H H 8.455 0.001 1 101 27 27 ASN CA C 53.83 0.01 1 102 27 27 ASN CB C 38.92 0.01 1 103 27 27 ASN N N 120.3 0.1 1 104 28 28 GLN H H 8.326 0.001 1 105 28 28 GLN CA C 56.47 0.01 1 106 28 28 GLN CB C 29.45 0.01 1 107 28 28 GLN N N 120.5 0.1 1 108 29 29 MET H H 8.343 0.001 1 109 29 29 MET CA C 56.02 0.01 1 110 29 29 MET CB C 32.87 0.01 1 111 29 29 MET N N 120.7 0.1 1 112 30 30 MET H H 8.362 0.001 1 113 30 30 MET CA C 55.86 0.01 1 114 30 30 MET CB C 33.08 0.01 1 115 30 30 MET N N 121.3 0.1 1 116 31 31 LYS H H 8.409 0.001 1 117 31 31 LYS CA C 56.65 0.01 1 118 31 31 LYS CB C 33.25 0.01 1 119 31 31 LYS N N 122.6 0.1 1 120 32 32 SER H H 8.346 0.001 1 121 32 32 SER CA C 58.41 0.01 1 122 32 32 SER CB C 64.07 0.01 1 123 32 32 SER N N 116.7 0.1 1 124 33 33 ARG H H 8.496 0.001 1 125 33 33 ARG CA C 56.42 0.01 1 126 33 33 ARG CB C 30.99 0.01 1 127 33 33 ARG N N 122.9 0.1 1 128 34 34 ASN H H 8.494 0.001 1 129 34 34 ASN CA C 53.23 0.01 1 130 34 34 ASN CB C 38.96 0.01 1 131 34 34 ASN N N 119.4 0.1 1 132 35 35 LEU H H 8.330 0.001 1 133 35 35 LEU CA C 55.38 0.01 1 134 35 35 LEU CB C 42.41 0.01 1 135 35 35 LEU N N 123.0 0.1 1 136 36 36 THR H H 8.206 0.001 1 137 36 36 THR CA C 62.28 0.01 1 138 36 36 THR CB C 69.92 0.01 1 139 36 36 THR N N 114.8 0.1 1 140 37 37 LYS H H 8.342 0.001 1 141 37 37 LYS CA C 56.51 0.01 1 142 37 37 LYS CB C 33.22 0.01 1 143 37 37 LYS N N 123.1 0.1 1 144 38 38 ASP H H 8.489 0.001 1 145 38 38 ASP CA C 53.00 0.01 1 146 38 38 ASP CB C 38.39 0.01 1 147 38 38 ASP N N 120.0 0.1 1 148 39 39 ARG H H 8.443 0.001 1 149 39 39 ARG CA C 56.31 0.01 1 150 39 39 ARG CB C 31.12 0.01 1 151 39 39 ARG N N 121.8 0.1 1 152 40 40 CYS H H 8.447 0.001 1 153 40 40 CYS CA C 54.95 0.01 1 154 40 40 CYS CB C 40.86 0.01 1 155 40 40 CYS N N 119.4 0.1 1 156 41 41 LYS H H 8.757 0.001 1 157 41 41 LYS CA C 54.61 0.01 1 158 41 41 LYS CB C 32.96 0.01 1 159 41 41 LYS N N 124.7 0.1 1 160 42 42 PRO CA C 63.12 0.01 1 161 42 42 PRO CB C 32.21 0.01 1 162 43 43 VAL H H 8.300 0.001 1 163 43 43 VAL CA C 62.17 0.01 1 164 43 43 VAL CB C 33.22 0.01 1 165 43 43 VAL N N 120.3 0.1 1 166 44 44 ASN H H 8.551 0.001 1 167 44 44 ASN CA C 53.08 0.01 1 168 44 44 ASN CB C 39.12 0.01 1 169 44 44 ASN N N 122.3 0.1 1 170 45 45 THR H H 8.116 0.001 1 171 45 45 THR CA C 61.94 0.01 1 172 45 45 THR CB C 69.73 0.01 1 173 45 45 THR N N 114.4 0.1 1 174 46 46 PHE H H 8.262 0.001 1 175 46 46 PHE CA C 57.69 0.01 1 176 46 46 PHE CB C 39.53 0.01 1 177 46 46 PHE N N 122.0 0.1 1 178 47 47 VAL H H 8.044 0.001 1 179 47 47 VAL CA C 62.37 0.01 1 180 47 47 VAL CB C 32.96 0.01 1 181 47 47 VAL N N 121.3 0.1 1 182 48 48 HIS H H 8.677 0.001 1 183 48 48 HIS CA C 55.31 0.01 1 184 48 48 HIS CB C 28.89 0.01 1 185 48 48 HIS N N 122.5 0.1 1 186 49 49 GLU H H 8.513 0.001 1 187 49 49 GLU CA C 55.63 0.01 1 188 49 49 GLU CB C 29.42 0.01 1 189 49 49 GLU N N 122.5 0.1 1 190 50 50 SER H H 8.530 0.001 1 191 50 50 SER CA C 58.21 0.01 1 192 50 50 SER CB C 63.95 0.01 1 193 50 50 SER N N 117.8 0.1 1 194 51 51 LEU H H 8.439 0.001 1 195 51 51 LEU CA C 55.41 0.01 1 196 51 51 LEU CB C 42.32 0.01 1 197 51 51 LEU N N 124.7 0.1 1 198 52 52 ALA H H 8.304 0.001 1 199 52 52 ALA CA C 52.79 0.01 1 200 52 52 ALA CB C 19.21 0.01 1 201 52 52 ALA N N 123.5 0.1 1 202 53 53 ASP H H 8.343 0.001 1 203 53 53 ASP CA C 53.10 0.01 1 204 53 53 ASP CB C 38.05 0.01 1 205 53 53 ASP N N 117.8 0.1 1 206 54 54 VAL H H 8.005 0.001 1 207 54 54 VAL CA C 62.73 0.01 1 208 54 54 VAL CB C 32.83 0.01 1 209 54 54 VAL N N 120.0 0.1 1 210 55 55 GLN H H 8.411 0.001 1 211 55 55 GLN CA C 56.09 0.01 1 212 55 55 GLN CB C 29.62 0.01 1 213 55 55 GLN N N 123.1 0.1 1 214 56 56 ALA H H 8.269 0.001 1 215 56 56 ALA CA C 52.64 0.01 1 216 56 56 ALA CB C 19.44 0.01 1 217 56 56 ALA N N 125.2 0.1 1 218 57 57 VAL H H 8.157 0.001 1 219 57 57 VAL CA C 62.52 0.01 1 220 57 57 VAL CB C 33.08 0.01 1 221 57 57 VAL N N 118.8 0.1 1 222 58 58 CYS H H 8.511 0.001 1 223 58 58 CYS CA C 55.31 0.01 1 224 58 58 CYS CB C 40.84 0.01 1 225 58 58 CYS N N 121.4 0.1 1 226 59 59 SER CA C 58.60 0.01 1 227 60 60 GLN H H 8.515 0.001 1 228 60 60 GLN CA C 55.85 0.01 1 229 60 60 GLN CB C 29.75 0.01 1 230 60 60 GLN N N 122.9 0.1 1 231 61 61 LYS H H 8.413 0.001 1 232 61 61 LYS CA C 56.47 0.01 1 233 61 61 LYS CB C 33.46 0.01 1 234 61 61 LYS N N 122.1 0.1 1 235 62 62 ASN H H 8.568 0.001 1 236 62 62 ASN CA C 53.22 0.01 1 237 62 62 ASN CB C 39.05 0.01 1 238 62 62 ASN N N 120.5 0.1 1 239 63 63 VAL H H 8.185 0.001 1 240 63 63 VAL CA C 62.06 0.01 1 241 63 63 VAL CB C 33.02 0.01 1 242 63 63 VAL N N 120.3 0.1 1 243 64 64 ALA H H 8.363 0.001 1 244 64 64 ALA CA C 52.46 0.01 1 245 64 64 ALA CB C 19.49 0.01 1 246 64 64 ALA N N 127.1 0.1 1 247 65 65 CYS H H 8.384 0.001 1 248 65 65 CYS CA C 55.04 0.01 1 249 65 65 CYS CB C 40.80 0.01 1 250 65 65 CYS N N 119.1 0.1 1 251 66 66 LYS H H 8.640 0.001 1 252 66 66 LYS CA C 56.68 0.01 1 253 66 66 LYS CB C 33.48 0.01 1 254 66 66 LYS N N 124.1 0.1 1 255 67 67 ASN H H 8.597 0.001 1 256 67 67 ASN CA C 54.27 0.01 1 257 67 67 ASN CB C 38.34 0.01 1 258 67 67 ASN N N 118.8 0.1 1 259 68 68 GLY H H 8.547 0.001 1 260 68 68 GLY CA C 45.70 0.01 1 261 68 68 GLY N N 110.2 0.1 1 262 69 69 GLN H H 7.954 0.001 1 263 69 69 GLN CA C 56.14 0.01 1 264 69 69 GLN CB C 29.61 0.01 1 265 69 69 GLN N N 119.8 0.1 1 266 70 70 THR H H 8.355 0.001 1 267 70 70 THR CA C 62.69 0.01 1 268 70 70 THR CB C 69.77 0.01 1 269 70 70 THR N N 114.0 0.1 1 270 71 71 ASN H H 8.436 0.001 1 271 71 71 ASN CA C 53.32 0.01 1 272 71 71 ASN CB C 38.25 0.01 1 273 71 71 ASN N N 119.0 0.1 1 274 72 72 CYS H H 8.148 0.001 1 275 72 72 CYS CA C 56.50 0.01 1 276 72 72 CYS CB C 41.36 0.01 1 277 72 72 CYS N N 117.8 0.1 1 278 73 73 TYR H H 8.345 0.001 1 279 73 73 TYR CA C 57.94 0.01 1 280 73 73 TYR CB C 38.95 0.01 1 281 73 73 TYR N N 121.9 0.1 1 282 74 74 GLN H H 8.351 0.001 1 283 74 74 GLN CA C 55.70 0.01 1 284 74 74 GLN CB C 29.92 0.01 1 285 74 74 GLN N N 122.2 0.1 1 286 75 75 SER H H 8.338 0.001 1 287 75 75 SER CA C 58.24 0.01 1 288 75 75 SER CB C 64.02 0.01 1 289 75 75 SER N N 117.4 0.1 1 290 76 76 TYR H H 8.286 0.001 1 291 76 76 TYR CA C 57.97 0.01 1 292 76 76 TYR CB C 39.20 0.01 1 293 76 76 TYR N N 122.1 0.1 1 294 77 77 SER H H 8.373 0.001 1 295 77 77 SER CA C 58.20 0.01 1 296 77 77 SER CB C 64.22 0.01 1 297 77 77 SER N N 117.1 0.1 1 298 78 78 THR H H 8.308 0.001 1 299 78 78 THR CA C 61.95 0.01 1 300 78 78 THR CB C 69.87 0.01 1 301 78 78 THR N N 115.8 0.1 1 302 79 79 MET H H 8.339 0.001 1 303 79 79 MET CA C 55.74 0.01 1 304 79 79 MET CB C 33.39 0.01 1 305 79 79 MET N N 122.3 0.1 1 306 80 80 SER H H 8.397 0.001 1 307 80 80 SER CA C 58.37 0.01 1 308 80 80 SER CB C 63.97 0.01 1 309 80 80 SER N N 117.5 0.1 1 310 81 81 ILE CA C 61.54 0.01 1 311 81 81 ILE CB C 38.87 0.01 1 312 82 82 THR H H 8.213 0.001 1 313 82 82 THR CA C 61.86 0.01 1 314 82 82 THR CB C 69.86 0.01 1 315 82 82 THR N N 117.1 0.1 1 316 83 83 ASP H H 8.450 0.001 1 317 83 83 ASP CA C 53.03 0.01 1 318 83 83 ASP CB C 38.48 0.01 1 319 83 83 ASP N N 121.2 0.1 1 320 84 84 CYS H H 8.474 0.001 1 321 84 84 CYS CA C 55.26 0.01 1 322 84 84 CYS CB C 40.49 0.01 1 323 84 84 CYS N N 119.3 0.1 1 324 86 86 GLU CA C 55.81 0.01 1 325 86 86 GLU CB C 29.11 0.01 1 326 87 87 THR H H 8.310 0.001 1 327 87 87 THR CA C 61.93 0.01 1 328 87 87 THR CB C 70.09 0.01 1 329 87 87 THR N N 114.9 0.1 1 330 88 88 GLY H H 8.435 0.001 1 331 88 88 GLY CA C 45.40 0.01 1 332 88 88 GLY N N 110.7 0.1 1 333 89 89 SER H H 8.282 0.001 1 334 89 89 SER CA C 58.33 0.01 1 335 89 89 SER CB C 64.12 0.01 1 336 89 89 SER N N 115.3 0.1 1 337 90 90 SER H H 8.454 0.001 1 338 90 90 SER CA C 58.46 0.01 1 339 90 90 SER CB C 63.86 0.01 1 340 90 90 SER N N 118.0 0.1 1 341 91 91 LYS H H 8.303 0.001 1 342 91 91 LYS CA C 56.91 0.01 1 343 91 91 LYS CB C 33.36 0.01 1 344 91 91 LYS N N 123.0 0.1 1 345 92 92 TYR H H 8.141 0.001 1 346 92 92 TYR CA C 55.47 0.01 1 347 92 92 TYR CB C 38.57 0.01 1 348 92 92 TYR N N 120.6 0.1 1 349 93 93 PRO CA C 63.14 0.01 1 350 93 93 PRO CB C 32.32 0.01 1 351 94 94 ASN H H 8.550 0.001 1 352 94 94 ASN CA C 53.30 0.01 1 353 94 94 ASN CB C 38.96 0.01 1 354 94 94 ASN N N 119.1 0.1 1 355 95 95 CYS CA C 55.16 0.01 1 356 96 96 ALA H H 8.421 0.001 1 357 96 96 ALA CA C 52.57 0.01 1 358 96 96 ALA CB C 19.37 0.01 1 359 96 96 ALA N N 125.2 0.1 1 360 97 97 TYR H H 8.135 0.001 1 361 97 97 TYR CA C 57.64 0.01 1 362 97 97 TYR CB C 39.23 0.01 1 363 97 97 TYR N N 120.1 0.1 1 364 98 98 LYS H H 8.408 0.001 1 365 98 98 LYS CA C 56.25 0.01 1 366 98 98 LYS CB C 33.52 0.01 1 367 98 98 LYS N N 123.4 0.1 1 368 99 99 THR H H 8.316 0.001 1 369 99 99 THR CA C 61.55 0.01 1 370 99 99 THR N N 115.5 0.1 1 371 100 100 THR H H 8.277 0.001 1 372 100 100 THR CA C 61.81 0.01 1 373 100 100 THR CB C 70.07 0.01 1 374 100 100 THR N N 115.6 0.1 1 375 101 101 GLN H H 8.441 0.001 1 376 101 101 GLN CA C 55.92 0.01 1 377 101 101 GLN CB C 29.70 0.01 1 378 101 101 GLN N N 122.5 0.1 1 379 102 102 ALA H H 8.369 0.001 1 380 102 102 ALA CA C 52.74 0.01 1 381 102 102 ALA CB C 19.34 0.01 1 382 102 102 ALA N N 125.0 0.1 1 383 103 103 ASN H H 8.401 0.001 1 384 103 103 ASN CA C 53.20 0.01 1 385 103 103 ASN CB C 38.90 0.01 1 386 103 103 ASN N N 117.9 0.1 1 387 104 104 LYS H H 8.296 0.001 1 388 104 104 LYS CA C 56.47 0.01 1 389 104 104 LYS CB C 33.30 0.01 1 390 104 104 LYS N N 121.5 0.1 1 391 105 105 HIS H H 8.664 0.001 1 392 105 105 HIS CA C 55.18 0.01 1 393 105 105 HIS CB C 29.09 0.01 1 394 105 105 HIS N N 119.8 0.1 1 395 106 106 ILE H H 8.305 0.001 1 396 106 106 ILE CA C 61.03 0.01 1 397 106 106 ILE CB C 38.99 0.01 1 398 106 106 ILE N N 123.0 0.1 1 399 107 107 ILE H H 8.462 0.001 1 400 107 107 ILE CA C 60.83 0.01 1 401 107 107 ILE CB C 38.47 0.01 1 402 107 107 ILE N N 126.4 0.1 1 403 108 108 VAL H H 8.405 0.001 1 404 108 108 VAL CA C 61.97 0.01 1 405 108 108 VAL CB C 32.97 0.01 1 406 108 108 VAL N N 125.7 0.1 1 407 109 109 ALA H H 8.443 0.001 1 408 109 109 ALA CA C 52.24 0.01 1 409 109 109 ALA CB C 19.55 0.01 1 410 109 109 ALA N N 127.6 0.1 1 411 110 110 CYS H H 8.486 0.001 1 412 110 110 CYS CA C 55.22 0.01 1 413 110 110 CYS CB C 40.78 0.01 1 414 110 110 CYS N N 118.6 0.1 1 415 111 111 GLU CA C 55.91 0.01 1 416 111 111 GLU CB C 29.27 0.01 1 417 112 112 GLY H H 8.428 0.001 1 418 112 112 GLY CA C 45.01 0.01 1 419 112 112 GLY N N 109.8 0.1 1 420 113 113 ASN H H 8.436 0.001 1 421 113 113 ASN CA C 51.32 0.01 1 422 113 113 ASN CB C 39.05 0.01 1 423 113 113 ASN N N 119.4 0.1 1 424 114 114 PRO CA C 63.39 0.001 1 425 114 114 PRO CB C 32.05 0.01 1 426 115 115 TYR H H 8.275 0.001 1 427 115 115 TYR CA C 58.06 0.01 1 428 115 115 TYR CB C 38.75 0.01 1 429 115 115 TYR N N 120.8 0.1 1 430 116 116 VAL H H 7.885 0.001 1 431 116 116 VAL CA C 59.30 0.01 1 432 116 116 VAL CB C 33.29 0.01 1 433 116 116 VAL N N 124.8 0.1 1 434 117 117 PRO CA C 62.95 0.01 1 435 117 117 PRO CB C 32.23 0.01 1 436 118 118 VAL H H 8.143 0.001 1 437 118 118 VAL CA C 62.38 0.01 1 438 118 118 VAL CB C 33.03 0.01 1 439 118 118 VAL N N 120.3 0.1 1 440 119 119 HIS H H 8.566 0.001 1 441 119 119 HIS CA C 54.87 0.01 1 442 119 119 HIS CB C 29.35 0.01 1 443 119 119 HIS N N 122.1 0.1 1 444 120 120 PHE H H 8.484 0.001 1 445 120 120 PHE CA C 57.76 0.01 1 446 120 120 PHE CB C 39.98 0.01 1 447 120 120 PHE N N 123.1 0.1 1 448 121 121 ASP H H 8.665 0.001 1 449 121 121 ASP CA C 52.69 0.01 1 450 121 121 ASP CB C 38.35 0.01 1 451 121 121 ASP N N 122.1 0.1 1 452 122 122 ALA H H 8.260 0.001 1 453 122 122 ALA CA C 52.64 0.01 1 454 122 122 ALA CB C 19.52 0.01 1 455 122 122 ALA N N 125.0 0.1 1 456 123 123 SER H H 8.282 0.001 1 457 123 123 SER CA C 58.50 0.01 1 458 123 123 SER CB C 63.94 0.01 1 459 123 123 SER N N 115.0 0.1 1 460 124 124 VAL H H 8.070 0.001 1 461 124 124 VAL CA C 61.32 0.01 1 462 124 124 VAL CB C 32.93 0.01 1 463 124 124 VAL N N 120.3 0.1 1 stop_ save_