data_4266 ####################### # Entry information # ####################### save_entry_information _Entry.Sf_category entry_information _Entry.Sf_framecode entry_information _Entry.ID 4266 _Entry.Title ; The Solution Structure of a Superpotent B-chain-shortened Single-replacement Insulin Analogue ; _Entry.Type macromolecule _Entry.Version_type original _Entry.Submission_date 1998-11-08 _Entry.Accession_date 1998-11-08 _Entry.Last_release_date . _Entry.Original_release_date . _Entry.Origination author _Entry.NMR_STAR_version 3.1.1.61 _Entry.Original_NMR_STAR_version 2.1 _Entry.Experimental_method NMR _Entry.Experimental_method_subtype . _Entry.Details . _Entry.BMRB_internal_directory_name . loop_ _Entry_author.Ordinal _Entry_author.Given_name _Entry_author.Family_name _Entry_author.First_initial _Entry_author.Middle_initials _Entry_author.Family_title _Entry_author.Entry_ID 1 Guenther Kurapkat . . . 4266 2 Michael Siedentop . . . 4266 3 Hans-Georg Gattner . . . 4266 4 Michael Hagelstein . . . 4266 5 Dietrich Brandenburg . . . 4266 6 Joachim Grotzinger . . . 4266 7 Axel Wollmer . . . 4266 stop_ loop_ _Data_set.Type _Data_set.Count _Data_set.Entry_ID assigned_chemical_shifts 1 4266 stop_ loop_ _Datum.Type _Datum.Count _Datum.Entry_ID '1H chemical shifts' 293 4266 stop_ loop_ _Release.Release_number _Release.Format_type _Release.Format_version _Release.Date _Release.Submission_date _Release.Type _Release.Author _Release.Detail _Release.Entry_ID 2 . . 1999-10-05 . original author 'Original release.' 4266 1 . . 2002-08-12 . update BMRB 'Modify the saveframe name.' 4266 stop_ save_ ############### # Citations # ############### save_entry_citation _Citation.Sf_category citations _Citation.Sf_framecode entry_citation _Citation.Entry_ID 4266 _Citation.ID 1 _Citation.Class 'entry citation' _Citation.CAS_abstract_code . _Citation.MEDLINE_UI_code 99190073 _Citation.DOI . _Citation.PubMed_ID . _Citation.Full_citation ; Kurapkat, G., Siedentop, M., Gattner, H-G., Hagelstein, M., Brandenburg, D., Grotzinger, J., and Wollmer, A., "The Solution Structure of a Superpotent B-chain-shortened Single-replacement Insulin Analogue," Protein Sci. 8, 499- 508 (1999). ; _Citation.Title ; The Solution Structure of a Superpotent B-chain-shortend Single-replacement Insulin Analogue ; _Citation.Status published _Citation.Type journal _Citation.Journal_abbrev 'Protein Sci.' _Citation.Journal_name_full 'Protein Science' _Citation.Journal_volume 8 _Citation.Journal_issue . _Citation.Journal_ASTM . _Citation.Journal_ISSN . _Citation.Journal_CSD . _Citation.Book_title . _Citation.Book_chapter_title . _Citation.Book_volume . _Citation.Book_series . _Citation.Book_publisher . _Citation.Book_publisher_city . _Citation.Book_ISBN . _Citation.Conference_title . _Citation.Conference_site . _Citation.Conference_state_province . _Citation.Conference_country . _Citation.Conference_start_date . _Citation.Conference_end_date . _Citation.Conference_abstract_number . _Citation.Thesis_institution . _Citation.Thesis_institution_city . _Citation.Thesis_institution_country . _Citation.WWW_URL . _Citation.Page_first 499 _Citation.Page_last 508 _Citation.Year 1999 _Citation.Details . loop_ _Citation_author.Ordinal _Citation_author.Given_name _Citation_author.Family_name _Citation_author.First_initial _Citation_author.Middle_initials _Citation_author.Family_title _Citation_author.Entry_ID _Citation_author.Citation_ID 1 Guenther Kurapkat . . . 4266 1 2 Michael Siedentop . . . 4266 1 3 Hans-Georg Gattner . . . 4266 1 4 Michael Hagelstein . . . 4266 1 5 Dietrich Brandenburg . . . 4266 1 6 Joachim Grotzinger . . . 4266 1 7 Axel Wollmer . . . 4266 1 stop_ loop_ _Citation_keyword.Keyword _Citation_keyword.Entry_ID _Citation_keyword.Citation_ID 'active conformation' 4266 1 'CD spectroscopy' 4266 1 insulin 4266 1 'NMR spectroscopy' 4266 1 receptor_binding 4266 1 structure 4266 1 superpotency 4266 1 stop_ save_ ############################################# # Molecular system (assembly) description # ############################################# save_system_D-AlaB26_DTI-amide _Assembly.Sf_category assembly _Assembly.Sf_framecode system_D-AlaB26_DTI-amide _Assembly.Entry_ID 4266 _Assembly.ID 1 _Assembly.Name [D-AlaB26]destetra(B27-B30)insulin-B26-amide _Assembly.BMRB_code . _Assembly.Number_of_components 2 _Assembly.Organic_ligands . _Assembly.Metal_ions . _Assembly.Non_standard_bonds . _Assembly.Ambiguous_conformational_states . _Assembly.Ambiguous_chem_comp_sites . _Assembly.Molecules_in_chemical_exchange . _Assembly.Paramagnetic no _Assembly.Thiol_state . _Assembly.Molecular_mass . _Assembly.Enzyme_commission_number . _Assembly.Details . _Assembly.DB_query_date . _Assembly.DB_query_revised_last_date . loop_ _Assembly_type.Type _Assembly_type.Entry_ID _Assembly_type.Assembly_ID monomer 4266 1 stop_ loop_ _Entity_assembly.ID _Entity_assembly.Entity_assembly_name _Entity_assembly.Entity_ID _Entity_assembly.Entity_label _Entity_assembly.Asym_ID _Entity_assembly.PDB_chain_ID _Entity_assembly.Experimental_data_reported _Entity_assembly.Physical_state _Entity_assembly.Conformational_isomer _Entity_assembly.Chemical_exchange_state _Entity_assembly.Magnetic_equivalence_group_code _Entity_assembly.Role _Entity_assembly.Details _Entity_assembly.Entry_ID _Entity_assembly.Assembly_ID 1 [D-AlaB26]DTI-amide_A-chain 1 $D-AlaB26_DTI-amide . . . native . . 1 . . 4266 1 2 [D-AlaB26]DTI-amide_B-chain 1 $D-AlaB26_DTI-amide . . . native . . 2 . . 4266 1 stop_ loop_ _Assembly_common_name.Name _Assembly_common_name.Type _Assembly_common_name.Entry_ID _Assembly_common_name.Assembly_ID [D-AlaB26]destetra(B27-B30)insulin-B26-amide system 4266 1 [D-AlaB26]DTI-amide abbreviation 4266 1 stop_ save_ #################################### # Biological polymers and ligands # #################################### save_D-AlaB26_DTI-amide _Entity.Sf_category entity _Entity.Sf_framecode D-AlaB26_DTI-amide _Entity.Entry_ID 4266 _Entity.ID 1 _Entity.BMRB_code . _Entity.Name [D-AlaB26]destetra(B27-B30)insulin-B26-amide _Entity.Type polymer _Entity.Polymer_common_type . _Entity.Polymer_type polypeptide(L) _Entity.Polymer_type_details . _Entity.Polymer_strand_ID . _Entity.Polymer_seq_one_letter_code_can . _Entity.Polymer_seq_one_letter_code ; GIVEQCCTSICSLYQLENYC NFVNQHLCGSHLVEALYLVC GERGFFA ; _Entity.Target_identifier . _Entity.Polymer_author_defined_seq . _Entity.Polymer_author_seq_details . _Entity.Ambiguous_conformational_states . _Entity.Ambiguous_chem_comp_sites . _Entity.Nstd_monomer . _Entity.Nstd_chirality . _Entity.Nstd_linkage . _Entity.Nonpolymer_comp_ID . _Entity.Nonpolymer_comp_label . _Entity.Number_of_monomers 47 _Entity.Number_of_nonpolymer_components . _Entity.Paramagnetic . _Entity.Thiol_state . _Entity.Src_method . _Entity.Parent_entity_ID . _Entity.Fragment . _Entity.Mutation . _Entity.EC_number . _Entity.Calc_isoelectric_point . _Entity.Formula_weight . _Entity.Formula_weight_exptl . _Entity.Formula_weight_exptl_meth . _Entity.Details . _Entity.DB_query_date . _Entity.DB_query_revised_last_date 2015-11-24 loop_ _Entity_db_link.Ordinal _Entity_db_link.Author_supplied _Entity_db_link.Database_code _Entity_db_link.Accession_code _Entity_db_link.Entry_mol_code _Entity_db_link.Entry_mol_name _Entity_db_link.Entry_experimental_method _Entity_db_link.Entry_structure_resolution _Entity_db_link.Entry_relation_type _Entity_db_link.Entry_details _Entity_db_link.Chimera_segment_ID _Entity_db_link.Seq_query_to_submitted_percent _Entity_db_link.Seq_subject_length _Entity_db_link.Seq_identity _Entity_db_link.Seq_positive _Entity_db_link.Seq_homology_expectation_val _Entity_db_link.Seq_align_begin _Entity_db_link.Seq_align_end _Entity_db_link.Seq_difference_details _Entity_db_link.Seq_alignment_details _Entity_db_link.Entry_ID _Entity_db_link.Entity_ID 1 no BMRB 1015 . "insulin B chain" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 2 no BMRB 1021 . "insulin B chain" . . . . . 51.06 30 100.00 100.00 2.43e-07 . . . . 4266 1 3 no BMRB 1025 . "insulin B chain" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 4 no BMRB 1444 . "insulin B chain" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 5 no BMRB 1633 . "insulin B chain" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 6 no PDB 1AI0 . "R6 Human Insulin Hexamer (Non-Symmetric), Nmr, 10 Structures" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 7 no PDB 1AIY . "R6 Human Insulin Hexamer (Symmetric), Nmr, 10 Structures" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 8 no PDB 1APH . "Conformational Changes In Cubic Insulin Crystals In The Ph Range 7-11" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 9 no PDB 1B17 . "Ph Affects Glu B13 Switching And Sulfate Binding In Cubic Insulin Crystals (Ph 5.00 Coordinates)" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 10 no PDB 1B18 . "Ph Affects Glu B13 Switching And Sulfate Binding In Cubic Insulin Crystals (Ph 5.53 Coordinates)" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 11 no PDB 1B19 . "Ph Affects Glu B13 Switching And Sulfate Binding In Cubic Insulin Crystals (Ph 5.80 Coordinates)" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 12 no PDB 1B2A . "Ph Affects Glu B13 Switching And Sulfate Binding In Cubic Insulin Crystals (Ph 6.00 Coordinates)" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 13 no PDB 1B2B . "Ph Affects Glu B13 Switching And Sulfate Binding In Cubic Insulin Crystals (Ph 6.16 Coordinates)" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 14 no PDB 1B2C . "Ph Affects Glu B13 Switching And Sulfate Binding In Cubic Insulin Crystals (Ph 6.26 Coordinates)" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 15 no PDB 1B2D . "Ph Affects Glu B13 Switching And Sulfate Binding In Cubic Insulin Crystals (Ph 6.35 Coordinates)" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 16 no PDB 1B2E . "Ph Affects Glu B13 Switching And Sulfate Binding In Cubic Insulin Crystals (Ph 6.50 Coordinates)" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 17 no PDB 1B2F . "Ph Affects Glu B13 Switching And Sulfate Binding In Cubic Insulin Crystals (Ph 6.98 Coordinates)" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 18 no PDB 1B2G . "Ph Affects Glu B13 Switching And Sulfate Binding In Cubic Insulin Crystals (Ph 9.00 Coordinates)" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 19 no PDB 1BEN . "Insulin Complexed With 4-Hydroxybenzamide" . . . . . 51.06 30 100.00 100.00 2.73e-07 . . . . 4266 1 20 no PDB 1BPH . "Conformational Changes In Cubic Insulin Crystals In The Ph Range 7-11" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 21 no PDB 1BZV . "[d-Alab26]-Des(B27-B30)-Insulin-B26-Amide A Superpotent Single-Replacement Insulin Analogue, Nmr, Minimized Average Structure" . . . . . 53.19 26 100.00 100.00 9.37e-08 . . . . 4266 1 22 no PDB 1CPH . "Conformational Changes In Cubic Insulin Crystals In The Ph Range 7-11" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 23 no PDB 1DPH . "Conformational Changes In Cubic Insulin Crystals In The Ph Range 7-11" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 24 no PDB 1EV3 . "Structure Of The Rhombohedral Form Of The M-cresol/insulin R6 Hexamer" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 25 no PDB 1EV6 . "Structure Of The Monoclinic Form Of The M-CresolINSULIN R6 Hexamer" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 26 no PDB 1EVR . "The Structure Of The ResorcinolINSULIN R6 HEXAMER" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 27 no PDB 1FU2 . "First Protein Structure Determined From X-Ray Powder Diffraction Data" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 28 no PDB 1FUB . "First Protein Structure Determined From X-Ray Powder Diffraction Data" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 29 no PDB 1G7A . "1.2 A Structure Of T3r3 Human Insulin At 100 K" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 30 no PDB 1G7B . "1.3 A Structure Of T3r3 Human Insulin At 100 K" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 31 no PDB 1GUJ . "Insulin At Ph 2: Structural Analysis Of The Conditions Promoting Insulin Fibre Formation." . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 32 no PDB 1HIS . "Structure And Dynamics Of Des-Pentapeptide-Insulin In Solution: The Molten-Globule Hypothesis" . . . . . 53.19 25 100.00 100.00 9.35e-08 . . . . 4266 1 33 no PDB 1HTV . "Crystal Structure Of Destripeptide (B28-B30) Insulin" . . . . . 53.19 27 100.00 100.00 7.94e-08 . . . . 4266 1 34 no PDB 1J73 . "Crystal Structure Of An Unstable Insulin Analog With Native Activity." . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 35 no PDB 1JCA . "Non-standard Design Of Unstable Insulin Analogues With Enhanced Activity" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 36 no PDB 1JCO . "Solution Structure Of The Monomeric [thr(B27)->pro,Pro(B28)- >thr] Insulin Mutant (Pt Insulin)" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 37 no PDB 1LPH . "Lys(B28)pro(B29)-Human Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 38 no PDB 1M5A . "Crystal Structure Of 2-Co(2+)-Insulin At 1.2a Resolution" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 39 no PDB 1MPJ . "X-Ray Crystallographic Studies On Hexameric Insulins In The Presence Of Helix-Stabilizing Agents, Thiocyanate, Methylparaben An" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 40 no PDB 1MSO . "T6 Human Insulin At 1.0 A Resolution" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 41 no PDB 1OS3 . "Dehydrated T6 Human Insulin At 100 K" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 42 no PDB 1OS4 . "Dehydrated T6 Human Insulin At 295 K" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 43 no PDB 1PID . "Bovine Despentapeptide Insulin" . . . . . 53.19 25 100.00 100.00 9.35e-08 . . . . 4266 1 44 no PDB 1Q4V . "Crystal Structure Of Allo-Ilea2-Insulin, An Inactive Chiral Analogue: Implications For The Mechanism Of Receptor" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 45 no PDB 1RWE . "Enhancing The Activity Of Insulin At Receptor Edge: Crystal Structure And Photo-Cross-Linking Of A8 Analogues" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 46 no PDB 1SF1 . "Nmr Structure Of Human Insulin Under Amyloidogenic Condition, 15 Structures" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 47 no PDB 1TRZ . "Crystallographic Evidence For Dual Coordination Around Zinc In The T3r3 Human Insulin Hexamer" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 48 no PDB 1TYL . "The Structure Of A Complex Of Hexameric Insulin And 4'- Hydroxyacetanilide" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 49 no PDB 1TYM . "The Structure Of A Complex Of Hexameric Insulin And 4'- Hydroxyacetanilide" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 50 no PDB 1UZ9 . "Crystallographic And Solution Studies Of N-Lithocholyl Insulin: A New Generation Of Prolonged-Acting Insulins." . . . . . 53.19 29 100.00 100.00 5.53e-08 . . . . 4266 1 51 no PDB 1WAV . "Crystal Structure Of Form B Monoclinic Crystal Of Insulin" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 52 no PDB 1XDA . "Structure Of Insulin" . . . . . 53.19 29 100.00 100.00 5.53e-08 . . . . 4266 1 53 no PDB 1XGL . "Human Insulin Disulfide Isomer, Nmr, 10 Structures" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 54 no PDB 1XW7 . "Diabetes-Associated Mutations In Human Insulin: Crystal Structure And Photo-Cross-Linking Studies Of A-Chain Variant Insulin Wa" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 55 no PDB 1ZEG . "Structure Of B28 Asp Insulin In Complex With Phenol" . . . . . 53.19 30 100.00 100.00 4.55e-08 . . . . 4266 1 56 no PDB 1ZEH . "Structure Of Insulin" . . . . . 53.19 30 100.00 100.00 4.55e-08 . . . . 4266 1 57 no PDB 1ZNI . Insulin . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 58 no PDB 1ZNJ . "Insulin, Monoclinic Crystal Form" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 59 no PDB 2A3G . "The Structure Of T6 Bovine Insulin" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 60 no PDB 2AIY . "R6 Human Insulin Hexamer (Symmetric), Nmr, 20 Structures" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 61 no PDB 2BN1 . "Insulin After A High Dose X-ray Burn" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 62 no PDB 2BN3 . "Insulin Before A High Dose X-Ray Burn" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 63 no PDB 2C8Q . "Insuline(1sec) And Uv Laser Excited Fluorescence" . . . . . 53.19 29 100.00 100.00 5.53e-08 . . . . 4266 1 64 no PDB 2C8R . "Insuline(60sec) And Uv Laser Excited Fluorescence" . . . . . 53.19 29 100.00 100.00 5.53e-08 . . . . 4266 1 65 no PDB 2CEU . "Despentapeptide Insulin In Acetic Acid (Ph 2)" . . . . . 53.19 25 100.00 100.00 9.35e-08 . . . . 4266 1 66 no PDB 2EFA . "Neutron Crystal Structure Of Cubic Insulin At Pd6.6" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 67 no PDB 2G4M . "Insulin Collected At 2.0 A Wavelength" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 68 no PDB 2G54 . "Crystal Structure Of Zn-Bound Human Insulin-Degrading Enzyme In Complex With Insulin B Chain" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 69 no PDB 2G56 . "Crystal Structure Of Human Insulin-degrading Enzyme In Complex With Insulin B Chain" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 70 no PDB 2HIU . "Nmr Structure Of Human Insulin In 20% Acetic Acid, Zinc- Free, 10 Structures" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 71 no PDB 2INS . "The Structure Of Des-Phe B1 Bovine Insulin" . . . . . 51.06 29 100.00 100.00 2.83e-07 . . . . 4266 1 72 no PDB 2JV1 . "Nmr Structure Of Human Insulin Monomer In 35% Cd3cn Zinc Free, 50 Structures" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 73 no PDB 2KJJ . "Dynamics Of Insulin Probed By 1h-Nmr Amide Proton Exchange A Flexibility Of The Receptor-Binding Surface" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 74 no PDB 2KXK . "Human Insulin Mutant A22gly-B31lys-B32arg" . . . . . 53.19 32 100.00 100.00 3.51e-08 . . . . 4266 1 75 no PDB 2LGB . "Modified A22gly-B31arg Human Insulin" . . . . . 53.19 31 100.00 100.00 4.26e-08 . . . . 4266 1 76 no PDB 2M1D . "Biosynthetic Engineered B28k-b29p Human Insulin Monomer Structure In In Water/acetonitrile Solutions." . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 77 no PDB 2M1E . "Biosynthetic Engineered B28k-b29p Human Insulin Monomer Structure In In Water Solutions" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 78 no PDB 2MVC . "Solution Structure Of Human Insulin At Ph 1.9" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 79 no PDB 2OLY . "Structure Of Human Insulin In Presence Of Urea At Ph 7.0" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 80 no PDB 2OLZ . "Structure Of Human Insulin In Presence Of Thiocyanate At Ph 7.0" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 81 no PDB 2OM0 . "Structure Of Human Insulin In Presence Of Urea At Ph 6.5" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 82 no PDB 2OM1 . "Structure Of Human Insulin In Presence Of Thiocyanate At Ph 6.5" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 83 no PDB 2OMG . "Structure Of Human Insulin Cocrystallized With Protamine And Urea" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 84 no PDB 2OMH . "Structure Of Human Insulin Cocrystallized With Arg-12 Peptide In Presence Of Urea" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 85 no PDB 2OMI . "Structure Of Human Insulin Cocrystallized With Protamine" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 86 no PDB 2QIU . "Structure Of Human Arg-Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 87 no PDB 2R34 . "Crystal Structure Of Mn Human Arg-Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 88 no PDB 2R35 . "Crystal Structure Of Rb Human Arg-Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 89 no PDB 2R36 . "Crystal Structure Of Ni Human Arg-Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 90 no PDB 2RN5 . "Humal Insulin Mutant B31lys-B32arg" . . . . . 53.19 32 100.00 100.00 3.51e-08 . . . . 4266 1 91 no PDB 2TCI . "X-Ray Crystallographic Studies On Hexameric Insulins In The Presence Of Helix-Stabilizing Agents, Thiocyanate, Methylparaben An" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 92 no PDB 2VJZ . "Crystal Structure Form Ultalente Insulin Microcrystals" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 93 no PDB 2VK0 . "Crystal Structure Form Ultalente Insulin Microcrystals" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 94 no PDB 2W44 . "Structure Deltaa1-a4 Insulin" . . . . . 53.19 29 100.00 100.00 5.53e-08 . . . . 4266 1 95 no PDB 2WC0 . "Crystal Structure Of Human Insulin Degrading Enzyme In Complex With Iodinated Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 96 no PDB 2WRU . "Semi-synthetic Highly Active Analogue Of Human Insulin Nmealab26-dti-nh2" . . . . . 53.19 26 100.00 100.00 9.37e-08 . . . . 4266 1 97 no PDB 2WRV . "Semi-Synthetic Highly Active Analogue Of Human Insulin Nmehisb26-Dti-Nh2" . . . . . 53.19 26 100.00 100.00 9.37e-08 . . . . 4266 1 98 no PDB 2WRW . "Semi-Synthetic Highly Active Analogue Of Human Insulin D- Prob26-Dti-Nh2" . . . . . 53.19 26 100.00 100.00 9.37e-08 . . . . 4266 1 99 no PDB 2WRX . "Semi-Synthetic Analogue Of Human Insulin Nmealab26-Insulin At Ph 3.0" . . . . . 53.19 30 100.00 100.00 4.27e-08 . . . . 4266 1 100 no PDB 2WS0 . "Semi-Synthetic Analogue Of Human Insulin Nmealab26-Insulin At Ph 7.5" . . . . . 53.19 30 100.00 100.00 4.27e-08 . . . . 4266 1 101 no PDB 2WS1 . "Semi-Synthetic Analogue Of Human Insulin Nmetyrb26-Insulin In Monomer Form" . . . . . 53.19 30 100.00 100.00 4.27e-08 . . . . 4266 1 102 no PDB 2WS6 . "Semi-Synthetic Analogue Of Human Insulin Nmetyrb26-Insulin In Hexamer Form" . . . . . 53.19 30 100.00 100.00 4.27e-08 . . . . 4266 1 103 no PDB 2ZP6 . "Crystal Structure Of Bovine Insulin (Hexameric Form)" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 104 no PDB 2ZPP . "Neutron Crystal Structure Of Cubic Insulin At Pd9" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 105 no PDB 3AIY . "R6 Human Insulin Hexamer (Symmetric), Nmr, Refined Average Structure" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 106 no PDB 3E7Y . "Structure Of Human Insulin" . . . . . 53.19 29 100.00 100.00 5.53e-08 . . . . 4266 1 107 no PDB 3E7Z . "Structure Of Human Insulin" . . . . . 53.19 29 100.00 100.00 5.53e-08 . . . . 4266 1 108 no PDB 3EXX . "Structure Of The T6 Human Insulin Derivative With Nickel At 1.35 A Resolution" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 109 no PDB 3FHP . "A Neutron Crystallographic Analysis Of A Porcine 2zn Insulin At 2.0 A Resolution" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 110 no PDB 3FQ9 . "Design Of An Insulin Analog With Enhanced Receptor-Binding Selectivity. Rationale, Structure, And Therapeutic Implications" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 111 no PDB 3GKY . "The Structural Basis Of An Er Stress-Associated Bottleneck In A Protein Folding Landscape" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 112 no PDB 3I3Z . "Human Insulin" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 113 no PDB 3I40 . "Human Insulin" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 114 no PDB 3ILG . "Crystal Structure Of Humnan Insulin Sr+2 Complex" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 115 no PDB 3INC . "Crystal Structure Of Human Insulin With Ni+2 Complex" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 116 no PDB 3INS . "Structure Of Insulin. Results Of Joint Neutron And X-ray Refinement" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 117 no PDB 3IR0 . "Crystal Structure Of Human Insulin Complexed With Cu+2 Metal Ion" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 118 no PDB 3KQ6 . "Enhancing The Therapeutic Properties Of A Protein By A Desig Binding Site, Structural Principles Of A Novel Long-Acting Analog" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 119 no PDB 3MTH . "X-Ray Crystallographic Studies On Hexameric Insulins In The Presence Of Helix-Stabilizing Agents, Thiocyanate, Methylparaben An" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 120 no PDB 3P33 . "Insulin Fibrillation Is The Janus Face Of Induced Fit. A Chiral Clamp Stabilizes The Native State At The Expense Of Activity" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 121 no PDB 3Q6E . "Human Insulin In Complex With Cucurbit[7]uril" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 122 no PDB 3RTO . "Acoustically Mounted Porcine Insulin Microcrystals Yield An X-Ray Sad Structure" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 123 no PDB 3T2A . "Tmao-Grown Cubic Insulin (Porcine)" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 124 no PDB 3TT8 . "Crystal Structure Analysis Of Cu Human Insulin Derivative" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 125 no PDB 3U4N . "A Novel Covalently Linked Insulin Dimer" . . . . . 51.06 29 100.00 100.00 5.01e-07 . . . . 4266 1 126 no PDB 3V19 . "Forestalling Insulin Fibrillation By Insertion Of A Chiral Clamp Mechanism-Based Application Of Protein Engineering To Global H" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 127 no PDB 3W11 . "Insulin Receptor Ectodomain Construct Comprising Domains L1-cr In Complex With Human Insulin, Alpha-ct Peptide(704-719) And Fab" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 128 no PDB 3W12 . "Insulin Receptor Ectodomain Construct Comprising Domains L1-cr In Complex With High-affinity Insulin Analogue [d-pro-b26]-dti-n" . . . . . 53.19 26 100.00 100.00 9.37e-08 . . . . 4266 1 129 no PDB 3W13 . "Insulin Receptor Ectodomain Construct Comprising Domains L1-cr In Complex With High-affinity Insulin Analogue [d-pro-b26]-dti-n" . . . . . 53.19 26 100.00 100.00 9.37e-08 . . . . 4266 1 130 no PDB 3W14 . "Insulin Receptor Ectodomain Construct Comprising Domains L1,cr,l2, Fniii-1 And Alphact Peptide In Complex With Bovine Insulin A" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 131 no PDB 3W7Y . "0.92a Structure Of 2zn Human Insulin At 100k" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 132 no PDB 3W7Z . "1.15a Structure Of Human 2zn Insulin At 293k" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 133 no PDB 3W80 . "Crystal Structure Of Dodecamer Human Insulin With Double C-axis Length Of The Hexamer 2 Zn Insulin Cell" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 134 no PDB 3ZQR . "Nmepheb25 Insulin Analogue Crystal Structure" . . . . . 51.06 30 100.00 100.00 2.73e-07 . . . . 4266 1 135 no PDB 3ZU1 . "Structure Of Lysb29(Nepsilon Omega-Carboxyheptadecanoyl) Des(B30) Human Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 136 no PDB 4A7E . "X-Ray Crystal Structure Of Porcine Insulin Flash-Cooled At High Pressure" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 137 no PDB 4AIY . "R6 Human Insulin Hexamer (Symmetric), Nmr, 'green' Substate, Average Structure" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 138 no PDB 4AJX . "Ligand Controlled Assembly Of Hexamers, Dihexamers, And Linear Multihexamer Structures By An Engineered Acylated Insulin" . . . . . 53.19 29 100.00 100.00 5.53e-08 . . . . 4266 1 139 no PDB 4AJZ . "Ligand Controlled Assembly Of Hexamers, Dihexamers, And Linear Multihexamer Structures By An Engineered Acylated Insulin" . . . . . 53.19 29 100.00 100.00 5.53e-08 . . . . 4266 1 140 no PDB 4AK0 . "Ligand Controlled Assembly Of Hexamers, Dihexamers, And Linear Multihexamer Structures By An Engineered Acylated Insulin" . . . . . 53.19 29 100.00 100.00 5.53e-08 . . . . 4266 1 141 no PDB 4AKJ . "Ligand Controlled Assembly Of Hexamers, Dihexamers, And Linear Multihexamer Structures By An Engineered Acylated Insulin" . . . . . 53.19 29 100.00 100.00 5.53e-08 . . . . 4266 1 142 no PDB 4BS3 . "Bovin Insulin Structure Determined By In Situ Crystal Analysis And Sulfur-sad Phasing At Room Temperature" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 143 no PDB 4E7T . "The Structure Of T6 Bovine Insulin" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 144 no PDB 4E7U . "The Structure Of T3r3 Bovine Insulin" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 145 no PDB 4E7V . "The Structure Of R6 Bovine Insulin" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 146 no PDB 4EWW . "Human Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 147 no PDB 4EWX . "Human Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 148 no PDB 4EWZ . "Human Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 149 no PDB 4EX0 . "Human Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 150 no PDB 4EX1 . "Human Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 151 no PDB 4EXX . "Human Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 152 no PDB 4EY1 . "Human Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 153 no PDB 4EY9 . "Human Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 154 no PDB 4EYD . "Human Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 155 no PDB 4EYN . "Human Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 156 no PDB 4EYP . "Human Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 157 no PDB 4F0N . "Human Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 158 no PDB 4F0O . "Human Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 159 no PDB 4F1A . "Human Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 160 no PDB 4F1B . "Human Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 161 no PDB 4F1C . "Human Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 162 no PDB 4F1D . "Human Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 163 no PDB 4F1F . "Human Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 164 no PDB 4F1G . "Human Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 165 no PDB 4F4T . "Human Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 166 no PDB 4F4V . "Human Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 167 no PDB 4F51 . "Human Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 168 no PDB 4F8F . "Human Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 169 no PDB 4FG3 . "Crystal Structure Analysis Of The Human Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 170 no PDB 4FKA . "High Resolution Structure Of The Manganese Derivative Of Insulin" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 171 no PDB 4GBC . "Crystal Structure Of Aspart Insulin At Ph 6.5" . . . . . 53.19 30 100.00 100.00 4.55e-08 . . . . 4266 1 172 no PDB 4GBI . "Crystal Structure Of Aspart Insulin At Ph 6.5" . . . . . 53.19 30 100.00 100.00 4.55e-08 . . . . 4266 1 173 no PDB 4GBK . "Crystal Structure Of Aspart Insulin At Ph 8.5" . . . . . 53.19 30 100.00 100.00 4.55e-08 . . . . 4266 1 174 no PDB 4GBL . "Crystal Structure Of Aspart Insulin At Ph 8.5" . . . . . 53.19 30 100.00 100.00 4.55e-08 . . . . 4266 1 175 no PDB 4GBN . "Crystal Structure Of Aspart Insulin At Ph 6.5" . . . . . 53.19 30 100.00 100.00 4.55e-08 . . . . 4266 1 176 no PDB 4I5Y . "Insulin Protein Crystallization Via Langmuir-blodgett" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 177 no PDB 4I5Z . "Insulin Protein Crystallization Via Langmuir-blodgett" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 178 no PDB 4IDW . "Polycrystalline T6 Bovine Insulin: Anisotropic Lattice Evolution And Novel Structure Refinement Strategy" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 179 no PDB 4IHN . "High Resolution Insulin By Langmuir-blodgett Modified Hanging Drop Vapour Diffusion" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 180 no PDB 4INS . "The Structure Of 2zn Pig Insulin Crystals At 1.5 Angstroms Resolution" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 181 no PDB 4IYD . "Insulin Glargine Crystal Structure 1" . . . . . 53.19 29 100.00 100.00 5.53e-08 . . . . 4266 1 182 no PDB 4IYF . "Insulin Glargine Crystal Structure 2" . . . . . 53.19 29 100.00 100.00 5.53e-08 . . . . 4266 1 183 no PDB 4M4F . "Radiation Damage Study Of Cu T6-insulin - 0.01 Mgy" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 184 no PDB 4M4H . "Radiation Damage Study Of Cu T6-insulin - 0.06 Mgy" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 185 no PDB 4M4I . "Radiation Damage Study Of Cu T6-insulin - 0.12 Mgy" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 186 no PDB 4M4J . "Radiation Damage Study Of Cu T6-insulin - 0.30 Mgy" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 187 no PDB 4M4L . "The Structure Of Cu T6 Bovine Insulin" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 188 no PDB 4M4M . "The Structure Of Ni T6 Bovine Insulin" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 189 no PDB 4OGA . "Insulin In Complex With Site 1 Of The Human Insulin Receptor" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 190 no PDB 4RXW . "Crystal Structure Of The Cobalt Human Insulin Derivative" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 191 no PDB 4UNE . "Human Insulin B26phe Mutant Crystal Structure" . . . . . 53.19 30 100.00 100.00 4.80e-08 . . . . 4266 1 192 no PDB 4UNG . "Human Insulin B26asn Mutant Crystal Structure" . . . . . 53.19 30 100.00 100.00 4.14e-08 . . . . 4266 1 193 no PDB 4XC4 . "Insulin Co-crystallizes In The Presence Of It Beta-cell Chaperone Sulfatide" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 194 no PDB 5AIY . "R6 Human Insulin Hexamer (Symmetric), Nmr, 'red' Substate, Average Structure" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 195 no PDB 5CNY . "Crystal Structure Of Human Zinc Insulin At Ph 5.5" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 196 no PDB 5CO2 . "Crystalization Of Human Zinc Insulin At Ph 5.5" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 197 no PDB 5CO6 . "Crystal Structure Of Human Zinc Insulin At Ph 6.5" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 198 no PDB 5CO9 . "Crystal Structure Of Human Zinc Insulin At Ph 6.5" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 199 no PDB 7INS . "Structure Of Porcine Insulin Cocrystallized With Clupeine Z" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 200 no PDB 9INS . "Monovalent Cation Binding In Cubic Insulin Crystals" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 201 no EMBL CAA08766 . "insulin [Homo sapiens]" . . . . . 53.19 59 100.00 100.00 1.35e-08 . . . . 4266 1 202 no GB AAA72171 . "insulin B chain [synthetic construct]" . . . . . 53.19 31 100.00 100.00 3.79e-08 . . . . 4266 1 203 no GB AAA72917 . "insulin beta chain, partial [synthetic construct]" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 204 no GB AAB25817 . "insulin B-chain, partial [Equus przewalskii]" . . . . . 53.19 30 100.00 100.00 4.85e-08 . . . . 4266 1 205 no GB AAI48489 . "INS-IGF2 readthrough transcript, partial [synthetic construct]" . . . . . 53.19 200 100.00 100.00 1.28e-09 . . . . 4266 1 206 no GB AAI53084 . "INS-IGF2 readthrough transcript [synthetic construct]" . . . . . 53.19 200 100.00 100.00 1.28e-09 . . . . 4266 1 207 no PRF 0510475A . "insulin B,24/25-Leu" . . . . . 53.19 30 100.00 100.00 4.46e-08 . . . . 4266 1 208 no PRF 550086A . insulin . . . . . 97.87 51 100.00 100.00 1.47e-23 . . . . 4266 1 209 no PRF 560164A . insulin . . . . . 97.87 51 97.83 97.83 8.37e-23 . . . . 4266 1 210 no PRF 580107B . insulin . . . . . 97.87 50 97.83 97.83 5.39e-21 . . . . 4266 1 211 no PRF 600165A . insulin . . . . . 97.87 51 100.00 100.00 1.55e-23 . . . . 4266 1 212 no REF NP_001035835 . "insulin, isoform 2 precursor [Homo sapiens]" . . . . . 53.19 200 100.00 100.00 1.28e-09 . . . . 4266 1 213 no REF XP_004050477 . "PREDICTED: insulin isoform 3 [Gorilla gorilla gorilla]" . . . . . 53.19 200 100.00 100.00 1.28e-09 . . . . 4266 1 214 no REF XP_006766071 . "PREDICTED: insulin-like [Myotis davidii]" . . . . . 53.19 128 100.00 100.00 1.51e-08 . . . . 4266 1 215 no REF XP_008576869 . "PREDICTED: insulin, isoform 2-like [Galeopterus variegatus]" . . . . . 53.19 200 100.00 100.00 1.28e-09 . . . . 4266 1 216 no REF XP_008697844 . "PREDICTED: insulin, isoform 2-like [Ursus maritimus]" . . . . . 53.19 202 100.00 100.00 1.29e-09 . . . . 4266 1 217 no SP F8WCM5 . "RecName: Full=Insulin, isoform 2; AltName: Full=INS-IGF2 readthrough transcript protein" . . . . . 53.19 200 100.00 100.00 1.28e-09 . . . . 4266 1 stop_ loop_ _Entity_common_name.Name _Entity_common_name.Type _Entity_common_name.Entry_ID _Entity_common_name.Entity_ID [D-AlaB26]destetra(B27-B30)insulin-B26-amide common 4266 1 [D-AlaB26]DTI-amide abbreviation 4266 1 stop_ loop_ _Entity_comp_index.ID _Entity_comp_index.Auth_seq_ID _Entity_comp_index.Comp_ID _Entity_comp_index.Comp_label _Entity_comp_index.Entry_ID _Entity_comp_index.Entity_ID 1 . GLY . 4266 1 2 . ILE . 4266 1 3 . VAL . 4266 1 4 . GLU . 4266 1 5 . GLN . 4266 1 6 . CYS . 4266 1 7 . CYS . 4266 1 8 . THR . 4266 1 9 . SER . 4266 1 10 . ILE . 4266 1 11 . CYS . 4266 1 12 . SER . 4266 1 13 . LEU . 4266 1 14 . TYR . 4266 1 15 . GLN . 4266 1 16 . LEU . 4266 1 17 . GLU . 4266 1 18 . ASN . 4266 1 19 . TYR . 4266 1 20 . CYS . 4266 1 21 . ASN . 4266 1 22 . PHE . 4266 1 23 . VAL . 4266 1 24 . ASN . 4266 1 25 . GLN . 4266 1 26 . HIS . 4266 1 27 . LEU . 4266 1 28 . CYS . 4266 1 29 . GLY . 4266 1 30 . SER . 4266 1 31 . HIS . 4266 1 32 . LEU . 4266 1 33 . VAL . 4266 1 34 . GLU . 4266 1 35 . ALA . 4266 1 36 . LEU . 4266 1 37 . TYR . 4266 1 38 . LEU . 4266 1 39 . VAL . 4266 1 40 . CYS . 4266 1 41 . GLY . 4266 1 42 . GLU . 4266 1 43 . ARG . 4266 1 44 . GLY . 4266 1 45 . PHE . 4266 1 46 . PHE . 4266 1 47 . ALA . 4266 1 stop_ loop_ _Entity_poly_seq.Hetero _Entity_poly_seq.Mon_ID _Entity_poly_seq.Num _Entity_poly_seq.Comp_index_ID _Entity_poly_seq.Entry_ID _Entity_poly_seq.Entity_ID . GLY 1 1 4266 1 . ILE 2 2 4266 1 . VAL 3 3 4266 1 . GLU 4 4 4266 1 . GLN 5 5 4266 1 . CYS 6 6 4266 1 . CYS 7 7 4266 1 . THR 8 8 4266 1 . SER 9 9 4266 1 . ILE 10 10 4266 1 . CYS 11 11 4266 1 . SER 12 12 4266 1 . LEU 13 13 4266 1 . TYR 14 14 4266 1 . GLN 15 15 4266 1 . LEU 16 16 4266 1 . GLU 17 17 4266 1 . ASN 18 18 4266 1 . TYR 19 19 4266 1 . CYS 20 20 4266 1 . ASN 21 21 4266 1 . PHE 22 22 4266 1 . VAL 23 23 4266 1 . ASN 24 24 4266 1 . GLN 25 25 4266 1 . HIS 26 26 4266 1 . LEU 27 27 4266 1 . CYS 28 28 4266 1 . GLY 29 29 4266 1 . SER 30 30 4266 1 . HIS 31 31 4266 1 . LEU 32 32 4266 1 . VAL 33 33 4266 1 . GLU 34 34 4266 1 . ALA 35 35 4266 1 . LEU 36 36 4266 1 . TYR 37 37 4266 1 . LEU 38 38 4266 1 . VAL 39 39 4266 1 . CYS 40 40 4266 1 . GLY 41 41 4266 1 . GLU 42 42 4266 1 . ARG 43 43 4266 1 . GLY 44 44 4266 1 . PHE 45 45 4266 1 . PHE 46 46 4266 1 . ALA 47 47 4266 1 stop_ save_ #################### # Natural source # #################### save_natural_source _Entity_natural_src_list.Sf_category natural_source _Entity_natural_src_list.Sf_framecode natural_source _Entity_natural_src_list.Entry_ID 4266 _Entity_natural_src_list.ID 1 loop_ _Entity_natural_src.ID _Entity_natural_src.Entity_ID _Entity_natural_src.Entity_label _Entity_natural_src.Entity_chimera_segment_ID _Entity_natural_src.NCBI_taxonomy_ID _Entity_natural_src.Type _Entity_natural_src.Common _Entity_natural_src.Organism_name_scientific _Entity_natural_src.Organism_name_common _Entity_natural_src.Organism_acronym _Entity_natural_src.ICTVdb_decimal_code _Entity_natural_src.Superkingdom _Entity_natural_src.Kingdom _Entity_natural_src.Genus _Entity_natural_src.Species _Entity_natural_src.Strain _Entity_natural_src.Variant _Entity_natural_src.Subvariant _Entity_natural_src.Organ _Entity_natural_src.Tissue _Entity_natural_src.Tissue_fraction _Entity_natural_src.Cell_line _Entity_natural_src.Cell_type _Entity_natural_src.ATCC_number _Entity_natural_src.Organelle _Entity_natural_src.Cellular_location _Entity_natural_src.Fragment _Entity_natural_src.Fraction _Entity_natural_src.Secretion _Entity_natural_src.Plasmid _Entity_natural_src.Plasmid_details _Entity_natural_src.Gene_mnemonic _Entity_natural_src.Dev_stage _Entity_natural_src.Details _Entity_natural_src.Citation_ID _Entity_natural_src.Citation_label _Entity_natural_src.Entry_ID _Entity_natural_src.Entity_natural_src_list_ID 1 1 $D-AlaB26_DTI-amide . 9606 . . 'Homo sapiens' human . . Eukaryota Metazoa Homo sapiens . . . . . . . . . . . . . . . . . . . . . 4266 1 stop_ save_ ######################### # Experimental source # ######################### save_experimental_source _Entity_experimental_src_list.Sf_category experimental_source _Entity_experimental_src_list.Sf_framecode experimental_source _Entity_experimental_src_list.Entry_ID 4266 _Entity_experimental_src_list.ID 1 loop_ _Entity_experimental_src.ID _Entity_experimental_src.Entity_ID _Entity_experimental_src.Entity_label _Entity_experimental_src.Entity_chimera_segment_ID _Entity_experimental_src.Production_method _Entity_experimental_src.Host_org_scientific_name _Entity_experimental_src.Host_org_name_common _Entity_experimental_src.Host_org_details _Entity_experimental_src.Host_org_NCBI_taxonomy_ID _Entity_experimental_src.Host_org_genus _Entity_experimental_src.Host_org_species _Entity_experimental_src.Host_org_strain _Entity_experimental_src.Host_org_variant _Entity_experimental_src.Host_org_subvariant _Entity_experimental_src.Host_org_organ _Entity_experimental_src.Host_org_tissue _Entity_experimental_src.Host_org_tissue_fraction _Entity_experimental_src.Host_org_cell_line _Entity_experimental_src.Host_org_cell_type _Entity_experimental_src.Host_org_cellular_location _Entity_experimental_src.Host_org_organelle _Entity_experimental_src.Host_org_gene _Entity_experimental_src.Host_org_culture_collection _Entity_experimental_src.Host_org_ATCC_number _Entity_experimental_src.Vector_type _Entity_experimental_src.PDBview_host_org_vector_name _Entity_experimental_src.PDBview_plasmid_name _Entity_experimental_src.Vector_name _Entity_experimental_src.Vector_details _Entity_experimental_src.Vendor_name _Entity_experimental_src.Host_org_dev_stage _Entity_experimental_src.Details _Entity_experimental_src.Citation_ID _Entity_experimental_src.Citation_label _Entity_experimental_src.Entry_ID _Entity_experimental_src.Entity_experimental_src_list_ID 1 1 $D-AlaB26_DTI-amide . 'chemically synthesized' . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4266 1 stop_ save_ ##################################### # Sample contents and methodology # ##################################### ######################## # Sample description # ######################## save_sample_one _Sample.Sf_category sample _Sample.Sf_framecode sample_one _Sample.Entry_ID 4266 _Sample.ID 1 _Sample.Type solution _Sample.Sub_type . _Sample.Details . _Sample.Aggregate_sample_number . _Sample.Solvent_system . _Sample.Preparation_date . _Sample.Preparation_expiration_date . _Sample.Polycrystallization_protocol . _Sample.Single_crystal_protocol . _Sample.Crystal_grow_apparatus . _Sample.Crystal_grow_atmosphere . _Sample.Crystal_grow_details . _Sample.Crystal_grow_method . _Sample.Crystal_grow_method_cit_ID . _Sample.Crystal_grow_pH . _Sample.Crystal_grow_pH_range . _Sample.Crystal_grow_pressure . _Sample.Crystal_grow_pressure_esd . _Sample.Crystal_grow_seeding . _Sample.Crystal_grow_seeding_cit_ID . _Sample.Crystal_grow_temp . _Sample.Crystal_grow_temp_details . _Sample.Crystal_grow_temp_esd . _Sample.Crystal_grow_time . _Sample.Oriented_sample_prep_protocol . _Sample.Lyophilization_cryo_protectant . _Sample.Storage_protocol . loop_ _Sample_component.ID _Sample_component.Mol_common_name _Sample_component.Isotopic_labeling _Sample_component.Assembly_ID _Sample_component.Assembly_label _Sample_component.Entity_ID _Sample_component.Entity_label _Sample_component.Product_ID _Sample_component.Type _Sample_component.Concentration_val _Sample_component.Concentration_val_min _Sample_component.Concentration_val_max _Sample_component.Concentration_val_units _Sample_component.Concentration_val_err _Sample_component.Vendor _Sample_component.Vendor_product_name _Sample_component.Vendor_product_code _Sample_component.Entry_ID _Sample_component.Sample_ID 1 [D-AlaB26]destetra(B27-B30)insulin-B26-amide . . . 1 $D-AlaB26_DTI-amide . . 4 . . mM . . . . 4266 1 stop_ save_ ####################### # Sample conditions # ####################### save_sample_conditions_one _Sample_condition_list.Sf_category sample_conditions _Sample_condition_list.Sf_framecode sample_conditions_one _Sample_condition_list.Entry_ID 4266 _Sample_condition_list.ID 1 _Sample_condition_list.Details . loop_ _Sample_condition_variable.Type _Sample_condition_variable.Val _Sample_condition_variable.Val_err _Sample_condition_variable.Val_units _Sample_condition_variable.Entry_ID _Sample_condition_variable.Sample_condition_list_ID pH* 1.9 0.2 na 4266 1 temperature 298 1 K 4266 1 stop_ save_ ######################### # Experimental detail # ######################### ################################## # NMR Spectrometer definitions # ################################## save_spectrometer_list _NMR_spectrometer.Sf_category NMR_spectrometer _NMR_spectrometer.Sf_framecode spectrometer_list _NMR_spectrometer.Entry_ID 4266 _NMR_spectrometer.ID 1 _NMR_spectrometer.Details 'spectrometer information not available' _NMR_spectrometer.Manufacturer unknown _NMR_spectrometer.Model unknown _NMR_spectrometer.Serial_number . _NMR_spectrometer.Field_strength 0 save_ save_NMR_spectrometer_list _NMR_spectrometer_list.Sf_category NMR_spectrometer_list _NMR_spectrometer_list.Sf_framecode NMR_spectrometer_list _NMR_spectrometer_list.Entry_ID 4266 _NMR_spectrometer_list.ID 1 loop_ _NMR_spectrometer_view.ID _NMR_spectrometer_view.Name _NMR_spectrometer_view.Manufacturer _NMR_spectrometer_view.Model _NMR_spectrometer_view.Serial_number _NMR_spectrometer_view.Field_strength _NMR_spectrometer_view.Details _NMR_spectrometer_view.Citation_ID _NMR_spectrometer_view.Citation_label _NMR_spectrometer_view.Entry_ID _NMR_spectrometer_view.NMR_spectrometer_list_ID 1 spectrometer_1 unknown unknown . 0 'spectrometer information not available' . . 4266 1 stop_ save_ ############################# # NMR applied experiments # ############################# save_experiment_list _Experiment_list.Sf_category experiment_list _Experiment_list.Sf_framecode experiment_list _Experiment_list.Entry_ID 4266 _Experiment_list.ID 1 _Experiment_list.Details . save_ #################### # NMR parameters # #################### ############################## # Assigned chemical shifts # ############################## ################################ # Chemical shift referencing # ################################ save_chemical_shift_reference_one _Chem_shift_reference.Sf_category chem_shift_reference _Chem_shift_reference.Sf_framecode chemical_shift_reference_one _Chem_shift_reference.Entry_ID 4266 _Chem_shift_reference.ID 1 _Chem_shift_reference.Details . loop_ _Chem_shift_ref.Atom_type _Chem_shift_ref.Atom_isotope_number _Chem_shift_ref.Mol_common_name _Chem_shift_ref.Atom_group _Chem_shift_ref.Concentration_val _Chem_shift_ref.Concentration_units _Chem_shift_ref.Solvent _Chem_shift_ref.Rank _Chem_shift_ref.Chem_shift_units _Chem_shift_ref.Chem_shift_val _Chem_shift_ref.Ref_method _Chem_shift_ref.Ref_type _Chem_shift_ref.Indirect_shift_ratio _Chem_shift_ref.External_ref_loc _Chem_shift_ref.External_ref_sample_geometry _Chem_shift_ref.External_ref_axis _Chem_shift_ref.Indirect_shift_ratio_cit_ID _Chem_shift_ref.Indirect_shift_ratio_cit_label _Chem_shift_ref.Ref_correction_type _Chem_shift_ref.Correction_val _Chem_shift_ref.Correction_val_cit_ID _Chem_shift_ref.Correction_val_cit_label _Chem_shift_ref.Entry_ID _Chem_shift_ref.Chem_shift_reference_ID H 1 DSS 'methyl protons' . . . . ppm 0.0 internal direct . . . 1.0 . . . . . . 4266 1 stop_ save_ ################################### # Assigned chemical shift lists # ################################### ################################################################### # Chemical Shift Ambiguity Index Value Definitions # # # # The values other than 1 are used for those atoms with different # # chemical shifts that cannot be assigned to stereospecific atoms # # or to specific residues or chains. # # # # Index Value Definition # # # # 1 Unique (including isolated methyl protons, # # geminal atoms, and geminal methyl # # groups with identical chemical shifts) # # (e.g. ILE HD11, HD12, HD13 protons) # # 2 Ambiguity of geminal atoms or geminal methyl # # proton groups (e.g. ASP HB2 and HB3 # # protons, LEU CD1 and CD2 carbons, or # # LEU HD11, HD12, HD13 and HD21, HD22, # # HD23 methyl protons) # # 3 Aromatic atoms on opposite sides of # # symmetrical rings (e.g. TYR HE1 and HE2 # # protons) # # 4 Intraresidue ambiguities (e.g. LYS HG and # # HD protons or TRP HZ2 and HZ3 protons) # # 5 Interresidue ambiguities (LYS 12 vs. LYS 27) # # 6 Intermolecular ambiguities (e.g. ASP 31 CA # # in monomer 1 and ASP 31 CA in monomer 2 # # of an asymmetrical homodimer, duplex # # DNA assignments, or other assignments # # that may apply to atoms in one or more # # molecule in the molecular assembly) # # 9 Ambiguous, specific ambiguity not defined # # # ################################################################### save_assigned_chemical_shifts _Assigned_chem_shift_list.Sf_category assigned_chemical_shifts _Assigned_chem_shift_list.Sf_framecode assigned_chemical_shifts _Assigned_chem_shift_list.Entry_ID 4266 _Assigned_chem_shift_list.ID 1 _Assigned_chem_shift_list.Sample_condition_list_ID 1 _Assigned_chem_shift_list.Sample_condition_list_label $sample_conditions_one _Assigned_chem_shift_list.Chem_shift_reference_ID 1 _Assigned_chem_shift_list.Chem_shift_reference_label $chemical_shift_reference_one _Assigned_chem_shift_list.Chem_shift_1H_err . _Assigned_chem_shift_list.Chem_shift_13C_err . _Assigned_chem_shift_list.Chem_shift_15N_err . _Assigned_chem_shift_list.Chem_shift_31P_err . _Assigned_chem_shift_list.Chem_shift_2H_err . _Assigned_chem_shift_list.Chem_shift_19F_err . _Assigned_chem_shift_list.Error_derivation_method . _Assigned_chem_shift_list.Details . _Assigned_chem_shift_list.Text_data_format . _Assigned_chem_shift_list.Text_data . loop_ _Chem_shift_experiment.Experiment_ID _Chem_shift_experiment.Experiment_name _Chem_shift_experiment.Sample_ID _Chem_shift_experiment.Sample_label _Chem_shift_experiment.Sample_state _Chem_shift_experiment.Entry_ID _Chem_shift_experiment.Assigned_chem_shift_list_ID . . 1 $sample_one . 4266 1 stop_ loop_ _Atom_chem_shift.ID _Atom_chem_shift.Assembly_atom_ID _Atom_chem_shift.Entity_assembly_ID _Atom_chem_shift.Entity_ID _Atom_chem_shift.Comp_index_ID _Atom_chem_shift.Seq_ID _Atom_chem_shift.Comp_ID _Atom_chem_shift.Atom_ID _Atom_chem_shift.Atom_type _Atom_chem_shift.Atom_isotope_number _Atom_chem_shift.Val _Atom_chem_shift.Val_err _Atom_chem_shift.Assign_fig_of_merit _Atom_chem_shift.Ambiguity_code _Atom_chem_shift.Occupancy _Atom_chem_shift.Resonance_ID _Atom_chem_shift.Auth_entity_assembly_ID _Atom_chem_shift.Auth_asym_ID _Atom_chem_shift.Auth_seq_ID _Atom_chem_shift.Auth_comp_ID _Atom_chem_shift.Auth_atom_ID _Atom_chem_shift.Details _Atom_chem_shift.Entry_ID _Atom_chem_shift.Assigned_chem_shift_list_ID 1 . 1 1 1 1 GLY HA2 H 1 3.992 . . . . . . . . . . . 4266 1 2 . 1 1 2 2 ILE H H 1 8.495 . . . . . . . . . . . 4266 1 3 . 1 1 2 2 ILE HA H 1 3.940 . . . . . . . . . . . 4266 1 4 . 1 1 2 2 ILE HB H 1 1.325 . . . . . . . . . . . 4266 1 5 . 1 1 2 2 ILE HG12 H 1 1.224 . . . . . . . . . . . 4266 1 6 . 1 1 2 2 ILE HG13 H 1 1.151 . . . . . . . . . . . 4266 1 7 . 1 1 2 2 ILE HD11 H 1 0.606 . . . . . . . . . . . 4266 1 8 . 1 1 2 2 ILE HD12 H 1 0.606 . . . . . . . . . . . 4266 1 9 . 1 1 2 2 ILE HD13 H 1 0.606 . . . . . . . . . . . 4266 1 10 . 1 1 2 2 ILE HG21 H 1 0.739 . . . . . . . . . . . 4266 1 11 . 1 1 2 2 ILE HG22 H 1 0.739 . . . . . . . . . . . 4266 1 12 . 1 1 2 2 ILE HG23 H 1 0.739 . . . . . . . . . . . 4266 1 13 . 1 1 3 3 VAL H H 1 8.098 . . . . . . . . . . . 4266 1 14 . 1 1 3 3 VAL HA H 1 3.629 . . . . . . . . . . . 4266 1 15 . 1 1 3 3 VAL HB H 1 1.906 . . . . . . . . . . . 4266 1 16 . 1 1 3 3 VAL HG11 H 1 0.864 . . . . . . . . . . . 4266 1 17 . 1 1 3 3 VAL HG12 H 1 0.864 . . . . . . . . . . . 4266 1 18 . 1 1 3 3 VAL HG13 H 1 0.864 . . . . . . . . . . . 4266 1 19 . 1 1 4 4 GLU H H 1 8.094 . . . . . . . . . . . 4266 1 20 . 1 1 4 4 GLU HA H 1 4.221 . . . . . . . . . . . 4266 1 21 . 1 1 4 4 GLU HB2 H 1 2.091 . . . . . . . . . . . 4266 1 22 . 1 1 4 4 GLU HB3 H 1 2.091 . . . . . . . . . . . 4266 1 23 . 1 1 4 4 GLU HG2 H 1 2.500 . . . . . . . . . . . 4266 1 24 . 1 1 4 4 GLU HG3 H 1 2.500 . . . . . . . . . . . 4266 1 25 . 1 1 5 5 GLN H H 1 8.229 . . . . . . . . . . . 4266 1 26 . 1 1 5 5 GLN HA H 1 4.054 . . . . . . . . . . . 4266 1 27 . 1 1 5 5 GLN HB2 H 1 2.099 . . . . . . . . . . . 4266 1 28 . 1 1 5 5 GLN HB3 H 1 2.099 . . . . . . . . . . . 4266 1 29 . 1 1 5 5 GLN HG2 H 1 2.483 . . . . . . . . . . . 4266 1 30 . 1 1 5 5 GLN HG3 H 1 2.399 . . . . . . . . . . . 4266 1 31 . 1 1 6 6 CYS H H 1 8.280 . . . . . . . . . . . 4266 1 32 . 1 1 6 6 CYS HA H 1 4.878 . . . . . . . . . . . 4266 1 33 . 1 1 6 6 CYS HB2 H 1 2.856 . . . . . . . . . . . 4266 1 34 . 1 1 6 6 CYS HB3 H 1 3.320 . . . . . . . . . . . 4266 1 35 . 1 1 7 7 CYS H H 1 8.260 . . . . . . . . . . . 4266 1 36 . 1 1 7 7 CYS HA H 1 4.830 . . . . . . . . . . . 4266 1 37 . 1 1 7 7 CYS HB2 H 1 3.302 . . . . . . . . . . . 4266 1 38 . 1 1 7 7 CYS HB3 H 1 3.760 . . . . . . . . . . . 4266 1 39 . 1 1 8 8 THR H H 1 8.239 . . . . . . . . . . . 4266 1 40 . 1 1 8 8 THR HA H 1 4.029 . . . . . . . . . . . 4266 1 41 . 1 1 8 8 THR HB H 1 4.372 . . . . . . . . . . . 4266 1 42 . 1 1 8 8 THR HG21 H 1 1.222 . . . . . . . . . . . 4266 1 43 . 1 1 8 8 THR HG22 H 1 1.222 . . . . . . . . . . . 4266 1 44 . 1 1 8 8 THR HG23 H 1 1.222 . . . . . . . . . . . 4266 1 45 . 1 1 9 9 SER H H 1 7.441 . . . . . . . . . . . 4266 1 46 . 1 1 9 9 SER HA H 1 4.763 . . . . . . . . . . . 4266 1 47 . 1 1 9 9 SER HB2 H 1 3.874 . . . . . . . . . . . 4266 1 48 . 1 1 9 9 SER HB3 H 1 4.028 . . . . . . . . . . . 4266 1 49 . 1 1 10 10 ILE H H 1 7.808 . . . . . . . . . . . 4266 1 50 . 1 1 10 10 ILE HA H 1 4.351 . . . . . . . . . . . 4266 1 51 . 1 1 10 10 ILE HB H 1 1.540 . . . . . . . . . . . 4266 1 52 . 1 1 10 10 ILE HG12 H 1 1.072 . . . . . . . . . . . 4266 1 53 . 1 1 10 10 ILE HG13 H 1 0.434 . . . . . . . . . . . 4266 1 54 . 1 1 10 10 ILE HD11 H 1 0.506 . . . . . . . . . . . 4266 1 55 . 1 1 10 10 ILE HD12 H 1 0.506 . . . . . . . . . . . 4266 1 56 . 1 1 10 10 ILE HD13 H 1 0.506 . . . . . . . . . . . 4266 1 57 . 1 1 10 10 ILE HG21 H 1 0.615 . . . . . . . . . . . 4266 1 58 . 1 1 10 10 ILE HG22 H 1 0.615 . . . . . . . . . . . 4266 1 59 . 1 1 10 10 ILE HG23 H 1 0.615 . . . . . . . . . . . 4266 1 60 . 1 1 11 11 CYS H H 1 9.676 . . . . . . . . . . . 4266 1 61 . 1 1 12 12 SER H H 1 8.739 . . . . . . . . . . . 4266 1 62 . 1 1 12 12 SER HA H 1 4.588 . . . . . . . . . . . 4266 1 63 . 1 1 12 12 SER HB2 H 1 4.292 . . . . . . . . . . . 4266 1 64 . 1 1 12 12 SER HB3 H 1 3.986 . . . . . . . . . . . 4266 1 65 . 1 1 13 13 LEU H H 1 8.610 . . . . . . . . . . . 4266 1 66 . 1 1 13 13 LEU HA H 1 3.845 . . . . . . . . . . . 4266 1 67 . 1 1 13 13 LEU HB2 H 1 1.332 . . . . . . . . . . . 4266 1 68 . 1 1 13 13 LEU HB3 H 1 1.397 . . . . . . . . . . . 4266 1 69 . 1 1 13 13 LEU HG H 1 1.332 . . . . . . . . . . . 4266 1 70 . 1 1 13 13 LEU HD11 H 1 0.785 . . . . . . . . . . . 4266 1 71 . 1 1 13 13 LEU HD12 H 1 0.785 . . . . . . . . . . . 4266 1 72 . 1 1 13 13 LEU HD13 H 1 0.785 . . . . . . . . . . . 4266 1 73 . 1 1 13 13 LEU HD21 H 1 0.723 . . . . . . . . . . . 4266 1 74 . 1 1 13 13 LEU HD22 H 1 0.723 . . . . . . . . . . . 4266 1 75 . 1 1 13 13 LEU HD23 H 1 0.723 . . . . . . . . . . . 4266 1 76 . 1 1 14 14 TYR H H 1 7.471 . . . . . . . . . . . 4266 1 77 . 1 1 14 14 TYR HA H 1 4.142 . . . . . . . . . . . 4266 1 78 . 1 1 14 14 TYR HB2 H 1 2.977 . . . . . . . . . . . 4266 1 79 . 1 1 14 14 TYR HB3 H 1 2.889 . . . . . . . . . . . 4266 1 80 . 1 1 14 14 TYR HD1 H 1 7.036 . . . . . . . . . . . 4266 1 81 . 1 1 14 14 TYR HE1 H 1 6.816 . . . . . . . . . . . 4266 1 82 . 1 1 15 15 GLN H H 1 7.541 . . . . . . . . . . . 4266 1 83 . 1 1 15 15 GLN HA H 1 3.967 . . . . . . . . . . . 4266 1 84 . 1 1 15 15 GLN HB2 H 1 2.017 . . . . . . . . . . . 4266 1 85 . 1 1 15 15 GLN HG2 H 1 2.383 . . . . . . . . . . . 4266 1 86 . 1 1 15 15 GLN HG3 H 1 2.383 . . . . . . . . . . . 4266 1 87 . 1 1 15 15 GLN HE21 H 1 7.474 . . . . . . . . . . . 4266 1 88 . 1 1 16 16 LEU H H 1 8.075 . . . . . . . . . . . 4266 1 89 . 1 1 16 16 LEU HA H 1 4.159 . . . . . . . . . . . 4266 1 90 . 1 1 16 16 LEU HB2 H 1 1.919 . . . . . . . . . . . 4266 1 91 . 1 1 16 16 LEU HB3 H 1 1.584 . . . . . . . . . . . 4266 1 92 . 1 1 16 16 LEU HG H 1 1.731 . . . . . . . . . . . 4266 1 93 . 1 1 16 16 LEU HD11 H 1 0.799 . . . . . . . . . . . 4266 1 94 . 1 1 16 16 LEU HD12 H 1 0.799 . . . . . . . . . . . 4266 1 95 . 1 1 16 16 LEU HD13 H 1 0.799 . . . . . . . . . . . 4266 1 96 . 1 1 16 16 LEU HD21 H 1 0.834 . . . . . . . . . . . 4266 1 97 . 1 1 16 16 LEU HD22 H 1 0.834 . . . . . . . . . . . 4266 1 98 . 1 1 16 16 LEU HD23 H 1 0.834 . . . . . . . . . . . 4266 1 99 . 1 1 17 17 GLU H H 1 8.064 . . . . . . . . . . . 4266 1 100 . 1 1 17 17 GLU HA H 1 4.162 . . . . . . . . . . . 4266 1 101 . 1 1 17 17 GLU HB2 H 1 2.035 . . . . . . . . . . . 4266 1 102 . 1 1 17 17 GLU HB3 H 1 2.110 . . . . . . . . . . . 4266 1 103 . 1 1 17 17 GLU HG2 H 1 2.311 . . . . . . . . . . . 4266 1 104 . 1 1 17 17 GLU HG3 H 1 2.552 . . . . . . . . . . . 4266 1 105 . 1 1 18 18 ASN H H 1 7.417 . . . . . . . . . . . 4266 1 106 . 1 1 18 18 ASN HA H 1 4.462 . . . . . . . . . . . 4266 1 107 . 1 1 18 18 ASN HB2 H 1 2.533 . . . . . . . . . . . 4266 1 108 . 1 1 18 18 ASN HB3 H 1 2.598 . . . . . . . . . . . 4266 1 109 . 1 1 18 18 ASN HD21 H 1 7.147 . . . . . . . . . . . 4266 1 110 . 1 1 18 18 ASN HD22 H 1 6.502 . . . . . . . . . . . 4266 1 111 . 1 1 19 19 TYR H H 1 7.894 . . . . . . . . . . . 4266 1 112 . 1 1 19 19 TYR HA H 1 4.463 . . . . . . . . . . . 4266 1 113 . 1 1 19 19 TYR HB2 H 1 2.994 . . . . . . . . . . . 4266 1 114 . 1 1 19 19 TYR HB3 H 1 3.300 . . . . . . . . . . . 4266 1 115 . 1 1 19 19 TYR HD1 H 1 7.303 . . . . . . . . . . . 4266 1 116 . 1 1 19 19 TYR HE1 H 1 6.747 . . . . . . . . . . . 4266 1 117 . 1 1 20 20 CYS H H 1 7.448 . . . . . . . . . . . 4266 1 118 . 1 1 20 20 CYS HA H 1 4.774 . . . . . . . . . . . 4266 1 119 . 1 1 20 20 CYS HB2 H 1 3.240 . . . . . . . . . . . 4266 1 120 . 1 1 20 20 CYS HB3 H 1 2.837 . . . . . . . . . . . 4266 1 121 . 1 1 21 21 ASN H H 1 8.256 . . . . . . . . . . . 4266 1 122 . 1 1 21 21 ASN HA H 1 4.703 . . . . . . . . . . . 4266 1 123 . 1 1 21 21 ASN HB2 H 1 2.861 . . . . . . . . . . . 4266 1 124 . 1 1 21 21 ASN HB3 H 1 2.758 . . . . . . . . . . . 4266 1 125 . 1 1 21 21 ASN HD21 H 1 6.700 . . . . . . . . . . . 4266 1 126 . 1 1 21 21 ASN HD22 H 1 7.509 . . . . . . . . . . . 4266 1 127 . 1 1 22 22 PHE HA H 1 4.252 . . . . . . . . . . . 4266 1 128 . 1 1 22 22 PHE HB2 H 1 3.144 . . . . . . . . . . . 4266 1 129 . 1 1 22 22 PHE HB3 H 1 3.144 . . . . . . . . . . . 4266 1 130 . 1 1 22 22 PHE HD1 H 1 7.197 . . . . . . . . . . . 4266 1 131 . 1 1 22 22 PHE HE1 H 1 7.334 . . . . . . . . . . . 4266 1 132 . 1 1 22 22 PHE HZ H 1 7.233 . . . . . . . . . . . 4266 1 133 . 1 1 23 23 VAL H H 1 8.134 . . . . . . . . . . . 4266 1 134 . 1 1 23 23 VAL HA H 1 4.114 . . . . . . . . . . . 4266 1 135 . 1 1 23 23 VAL HB H 1 1.886 . . . . . . . . . . . 4266 1 136 . 1 1 23 23 VAL HG11 H 1 0.841 . . . . . . . . . . . 4266 1 137 . 1 1 23 23 VAL HG12 H 1 0.841 . . . . . . . . . . . 4266 1 138 . 1 1 23 23 VAL HG13 H 1 0.841 . . . . . . . . . . . 4266 1 139 . 1 1 23 23 VAL HG21 H 1 0.841 . . . . . . . . . . . 4266 1 140 . 1 1 23 23 VAL HG22 H 1 0.841 . . . . . . . . . . . 4266 1 141 . 1 1 23 23 VAL HG23 H 1 0.841 . . . . . . . . . . . 4266 1 142 . 1 1 24 24 ASN H H 1 8.453 . . . . . . . . . . . 4266 1 143 . 1 1 24 24 ASN HA H 1 4.705 . . . . . . . . . . . 4266 1 144 . 1 1 24 24 ASN HB2 H 1 2.707 . . . . . . . . . . . 4266 1 145 . 1 1 24 24 ASN HB3 H 1 2.707 . . . . . . . . . . . 4266 1 146 . 1 1 24 24 ASN HD21 H 1 7.324 . . . . . . . . . . . 4266 1 147 . 1 1 24 24 ASN HD22 H 1 6.897 . . . . . . . . . . . 4266 1 148 . 1 1 25 25 GLN H H 1 8.403 . . . . . . . . . . . 4266 1 149 . 1 1 25 25 GLN HA H 1 4.480 . . . . . . . . . . . 4266 1 150 . 1 1 25 25 GLN HB2 H 1 2.128 . . . . . . . . . . . 4266 1 151 . 1 1 25 25 GLN HB3 H 1 1.899 . . . . . . . . . . . 4266 1 152 . 1 1 25 25 GLN HG2 H 1 2.252 . . . . . . . . . . . 4266 1 153 . 1 1 25 25 GLN HG3 H 1 2.252 . . . . . . . . . . . 4266 1 154 . 1 1 25 25 GLN HE21 H 1 7.324 . . . . . . . . . . . 4266 1 155 . 1 1 25 25 GLN HE22 H 1 6.782 . . . . . . . . . . . 4266 1 156 . 1 1 26 26 HIS H H 1 8.617 . . . . . . . . . . . 4266 1 157 . 1 1 26 26 HIS HA H 1 4.440 . . . . . . . . . . . 4266 1 158 . 1 1 26 26 HIS HB2 H 1 3.247 . . . . . . . . . . . 4266 1 159 . 1 1 26 26 HIS HB3 H 1 3.543 . . . . . . . . . . . 4266 1 160 . 1 1 26 26 HIS HE1 H 1 8.564 . . . . . . . . . . . 4266 1 161 . 1 1 26 26 HIS HD1 H 1 7.381 . . . . . . . . . . . 4266 1 162 . 1 1 27 27 LEU H H 1 8.967 . . . . . . . . . . . 4266 1 163 . 1 1 27 27 LEU HA H 1 4.497 . . . . . . . . . . . 4266 1 164 . 1 1 27 27 LEU HB2 H 1 1.757 . . . . . . . . . . . 4266 1 165 . 1 1 27 27 LEU HG H 1 1.600 . . . . . . . . . . . 4266 1 166 . 1 1 27 27 LEU HD11 H 1 0.882 . . . . . . . . . . . 4266 1 167 . 1 1 27 27 LEU HD12 H 1 0.882 . . . . . . . . . . . 4266 1 168 . 1 1 27 27 LEU HD13 H 1 0.882 . . . . . . . . . . . 4266 1 169 . 1 1 27 27 LEU HD21 H 1 0.721 . . . . . . . . . . . 4266 1 170 . 1 1 27 27 LEU HD22 H 1 0.721 . . . . . . . . . . . 4266 1 171 . 1 1 27 27 LEU HD23 H 1 0.721 . . . . . . . . . . . 4266 1 172 . 1 1 28 28 CYS H H 1 8.312 . . . . . . . . . . . 4266 1 173 . 1 1 28 28 CYS HA H 1 4.962 . . . . . . . . . . . 4266 1 174 . 1 1 28 28 CYS HB2 H 1 3.211 . . . . . . . . . . . 4266 1 175 . 1 1 28 28 CYS HB3 H 1 2.951 . . . . . . . . . . . 4266 1 176 . 1 1 29 29 GLY H H 1 9.219 . . . . . . . . . . . 4266 1 177 . 1 1 29 29 GLY HA2 H 1 3.980 . . . . . . . . . . . 4266 1 178 . 1 1 29 29 GLY HA3 H 1 3.823 . . . . . . . . . . . 4266 1 179 . 1 1 30 30 SER H H 1 9.056 . . . . . . . . . . . 4266 1 180 . 1 1 30 30 SER HA H 1 4.112 . . . . . . . . . . . 4266 1 181 . 1 1 30 30 SER HB2 H 1 3.890 . . . . . . . . . . . 4266 1 182 . 1 1 30 30 SER HB3 H 1 3.890 . . . . . . . . . . . 4266 1 183 . 1 1 31 31 HIS H H 1 7.999 . . . . . . . . . . . 4266 1 184 . 1 1 31 31 HIS HA H 1 4.514 . . . . . . . . . . . 4266 1 185 . 1 1 31 31 HIS HB2 H 1 3.576 . . . . . . . . . . . 4266 1 186 . 1 1 31 31 HIS HB3 H 1 3.305 . . . . . . . . . . . 4266 1 187 . 1 1 31 31 HIS HE1 H 1 8.671 . . . . . . . . . . . 4266 1 188 . 1 1 31 31 HIS HD1 H 1 7.458 . . . . . . . . . . . 4266 1 189 . 1 1 32 32 LEU H H 1 7.060 . . . . . . . . . . . 4266 1 190 . 1 1 32 32 LEU HA H 1 4.002 . . . . . . . . . . . 4266 1 191 . 1 1 32 32 LEU HB2 H 1 1.892 . . . . . . . . . . . 4266 1 192 . 1 1 32 32 LEU HB3 H 1 1.233 . . . . . . . . . . . 4266 1 193 . 1 1 32 32 LEU HG H 1 1.319 . . . . . . . . . . . 4266 1 194 . 1 1 32 32 LEU HD11 H 1 0.930 . . . . . . . . . . . 4266 1 195 . 1 1 32 32 LEU HD12 H 1 0.930 . . . . . . . . . . . 4266 1 196 . 1 1 32 32 LEU HD13 H 1 0.930 . . . . . . . . . . . 4266 1 197 . 1 1 32 32 LEU HD21 H 1 0.930 . . . . . . . . . . . 4266 1 198 . 1 1 32 32 LEU HD22 H 1 0.930 . . . . . . . . . . . 4266 1 199 . 1 1 32 32 LEU HD23 H 1 0.930 . . . . . . . . . . . 4266 1 200 . 1 1 33 33 VAL H H 1 7.176 . . . . . . . . . . . 4266 1 201 . 1 1 33 33 VAL HA H 1 3.326 . . . . . . . . . . . 4266 1 202 . 1 1 33 33 VAL HB H 1 2.047 . . . . . . . . . . . 4266 1 203 . 1 1 33 33 VAL HG11 H 1 0.954 . . . . . . . . . . . 4266 1 204 . 1 1 33 33 VAL HG12 H 1 0.954 . . . . . . . . . . . 4266 1 205 . 1 1 33 33 VAL HG13 H 1 0.954 . . . . . . . . . . . 4266 1 206 . 1 1 33 33 VAL HG21 H 1 0.954 . . . . . . . . . . . 4266 1 207 . 1 1 33 33 VAL HG22 H 1 0.954 . . . . . . . . . . . 4266 1 208 . 1 1 33 33 VAL HG23 H 1 0.954 . . . . . . . . . . . 4266 1 209 . 1 1 34 34 GLU H H 1 7.938 . . . . . . . . . . . 4266 1 210 . 1 1 34 34 GLU HA H 1 4.090 . . . . . . . . . . . 4266 1 211 . 1 1 34 34 GLU HB2 H 1 2.083 . . . . . . . . . . . 4266 1 212 . 1 1 34 34 GLU HB3 H 1 2.083 . . . . . . . . . . . 4266 1 213 . 1 1 34 34 GLU HG2 H 1 2.533 . . . . . . . . . . . 4266 1 214 . 1 1 34 34 GLU HG3 H 1 2.169 . . . . . . . . . . . 4266 1 215 . 1 1 35 35 ALA H H 1 7.748 . . . . . . . . . . . 4266 1 216 . 1 1 35 35 ALA HA H 1 4.081 . . . . . . . . . . . 4266 1 217 . 1 1 35 35 ALA HB1 H 1 1.485 . . . . . . . . . . . 4266 1 218 . 1 1 35 35 ALA HB2 H 1 1.485 . . . . . . . . . . . 4266 1 219 . 1 1 35 35 ALA HB3 H 1 1.485 . . . . . . . . . . . 4266 1 220 . 1 1 36 36 LEU H H 1 8.063 . . . . . . . . . . . 4266 1 221 . 1 1 36 36 LEU HA H 1 3.903 . . . . . . . . . . . 4266 1 222 . 1 1 36 36 LEU HG H 1 1.490 . . . . . . . . . . . 4266 1 223 . 1 1 36 36 LEU HD11 H 1 0.659 . . . . . . . . . . . 4266 1 224 . 1 1 36 36 LEU HD12 H 1 0.659 . . . . . . . . . . . 4266 1 225 . 1 1 36 36 LEU HD13 H 1 0.659 . . . . . . . . . . . 4266 1 226 . 1 1 36 36 LEU HD21 H 1 0.465 . . . . . . . . . . . 4266 1 227 . 1 1 36 36 LEU HD22 H 1 0.465 . . . . . . . . . . . 4266 1 228 . 1 1 36 36 LEU HD23 H 1 0.465 . . . . . . . . . . . 4266 1 229 . 1 1 37 37 TYR H H 1 8.173 . . . . . . . . . . . 4266 1 230 . 1 1 37 37 TYR HA H 1 4.256 . . . . . . . . . . . 4266 1 231 . 1 1 37 37 TYR HB2 H 1 3.130 . . . . . . . . . . . 4266 1 232 . 1 1 37 37 TYR HB3 H 1 3.130 . . . . . . . . . . . 4266 1 233 . 1 1 37 37 TYR HD1 H 1 7.112 . . . . . . . . . . . 4266 1 234 . 1 1 37 37 TYR HE1 H 1 6.756 . . . . . . . . . . . 4266 1 235 . 1 1 38 38 LEU H H 1 7.855 . . . . . . . . . . . 4266 1 236 . 1 1 38 38 LEU HA H 1 4.081 . . . . . . . . . . . 4266 1 237 . 1 1 38 38 LEU HB2 H 1 1.921 . . . . . . . . . . . 4266 1 238 . 1 1 38 38 LEU HB3 H 1 1.648 . . . . . . . . . . . 4266 1 239 . 1 1 38 38 LEU HG H 1 1.833 . . . . . . . . . . . 4266 1 240 . 1 1 38 38 LEU HD11 H 1 0.916 . . . . . . . . . . . 4266 1 241 . 1 1 38 38 LEU HD12 H 1 0.916 . . . . . . . . . . . 4266 1 242 . 1 1 38 38 LEU HD13 H 1 0.916 . . . . . . . . . . . 4266 1 243 . 1 1 38 38 LEU HD21 H 1 0.916 . . . . . . . . . . . 4266 1 244 . 1 1 38 38 LEU HD22 H 1 0.916 . . . . . . . . . . . 4266 1 245 . 1 1 38 38 LEU HD23 H 1 0.916 . . . . . . . . . . . 4266 1 246 . 1 1 39 39 VAL H H 1 8.511 . . . . . . . . . . . 4266 1 247 . 1 1 39 39 VAL HA H 1 3.847 . . . . . . . . . . . 4266 1 248 . 1 1 39 39 VAL HB H 1 2.096 . . . . . . . . . . . 4266 1 249 . 1 1 39 39 VAL HG11 H 1 1.011 . . . . . . . . . . . 4266 1 250 . 1 1 39 39 VAL HG12 H 1 1.011 . . . . . . . . . . . 4266 1 251 . 1 1 39 39 VAL HG13 H 1 1.011 . . . . . . . . . . . 4266 1 252 . 1 1 39 39 VAL HG21 H 1 0.872 . . . . . . . . . . . 4266 1 253 . 1 1 39 39 VAL HG22 H 1 0.872 . . . . . . . . . . . 4266 1 254 . 1 1 39 39 VAL HG23 H 1 0.872 . . . . . . . . . . . 4266 1 255 . 1 1 40 40 CYS H H 1 8.724 . . . . . . . . . . . 4266 1 256 . 1 1 40 40 CYS HA H 1 4.777 . . . . . . . . . . . 4266 1 257 . 1 1 40 40 CYS HB2 H 1 3.215 . . . . . . . . . . . 4266 1 258 . 1 1 40 40 CYS HB3 H 1 2.931 . . . . . . . . . . . 4266 1 259 . 1 1 41 41 GLY H H 1 7.721 . . . . . . . . . . . 4266 1 260 . 1 1 41 41 GLY HA2 H 1 3.935 . . . . . . . . . . . 4266 1 261 . 1 1 41 41 GLY HA3 H 1 3.935 . . . . . . . . . . . 4266 1 262 . 1 1 42 42 GLU H H 1 8.403 . . . . . . . . . . . 4266 1 263 . 1 1 42 42 GLU HA H 1 4.225 . . . . . . . . . . . 4266 1 264 . 1 1 42 42 GLU HB2 H 1 2.178 . . . . . . . . . . . 4266 1 265 . 1 1 42 42 GLU HB3 H 1 2.086 . . . . . . . . . . . 4266 1 266 . 1 1 42 42 GLU HG2 H 1 2.506 . . . . . . . . . . . 4266 1 267 . 1 1 42 42 GLU HG3 H 1 2.506 . . . . . . . . . . . 4266 1 268 . 1 1 43 43 ARG H H 1 7.982 . . . . . . . . . . . 4266 1 269 . 1 1 43 43 ARG HA H 1 4.208 . . . . . . . . . . . 4266 1 270 . 1 1 43 43 ARG HB2 H 1 1.947 . . . . . . . . . . . 4266 1 271 . 1 1 43 43 ARG HB3 H 1 1.947 . . . . . . . . . . . 4266 1 272 . 1 1 43 43 ARG HG2 H 1 1.756 . . . . . . . . . . . 4266 1 273 . 1 1 43 43 ARG HG3 H 1 1.756 . . . . . . . . . . . 4266 1 274 . 1 1 44 44 GLY H H 1 7.692 . . . . . . . . . . . 4266 1 275 . 1 1 44 44 GLY HA2 H 1 3.810 . . . . . . . . . . . 4266 1 276 . 1 1 44 44 GLY HA3 H 1 3.973 . . . . . . . . . . . 4266 1 277 . 1 1 45 45 PHE H H 1 7.719 . . . . . . . . . . . 4266 1 278 . 1 1 45 45 PHE HA H 1 4.839 . . . . . . . . . . . 4266 1 279 . 1 1 45 45 PHE HB2 H 1 2.935 . . . . . . . . . . . 4266 1 280 . 1 1 45 45 PHE HB3 H 1 3.106 . . . . . . . . . . . 4266 1 281 . 1 1 45 45 PHE HD1 H 1 6.939 . . . . . . . . . . . 4266 1 282 . 1 1 45 45 PHE HE1 H 1 7.069 . . . . . . . . . . . 4266 1 283 . 1 1 46 46 PHE H H 1 8.362 . . . . . . . . . . . 4266 1 284 . 1 1 46 46 PHE HA H 1 4.532 . . . . . . . . . . . 4266 1 285 . 1 1 46 46 PHE HB2 H 1 3.098 . . . . . . . . . . . 4266 1 286 . 1 1 46 46 PHE HB3 H 1 3.098 . . . . . . . . . . . 4266 1 287 . 1 1 46 46 PHE HD1 H 1 7.233 . . . . . . . . . . . 4266 1 288 . 1 1 46 46 PHE HE1 H 1 7.333 . . . . . . . . . . . 4266 1 289 . 1 1 47 47 ALA H H 1 8.015 . . . . . . . . . . . 4266 1 290 . 1 1 47 47 ALA HA H 1 4.216 . . . . . . . . . . . 4266 1 291 . 1 1 47 47 ALA HB1 H 1 1.164 . . . . . . . . . . . 4266 1 292 . 1 1 47 47 ALA HB2 H 1 1.164 . . . . . . . . . . . 4266 1 293 . 1 1 47 47 ALA HB3 H 1 1.164 . . . . . . . . . . . 4266 1 stop_ save_