data_3394 ####################### # Entry information # ####################### save_entry_information _Saveframe_category entry_information _Entry_title ; The solution structure of the leucine zipper motif of the Jun oncoprotein homodimer ; _BMRB_accession_number 3394 _BMRB_flat_file_name bmr3394.str _Entry_type update _Submission_date 1995-07-31 _Accession_date 1996-03-25 _Entry_origination BMRB _NMR_STAR_version 2.1.1 _Experimental_method NMR _Details . loop_ _Author_ordinal _Author_family_name _Author_given_name _Author_middle_initials _Author_family_title 1 Junius F. Keith . 2 Weiss Anthony . . 3 King Glenn F. . stop_ loop_ _Saveframe_category_type _Saveframe_category_type_count assigned_chemical_shifts 1 stop_ loop_ _Data_type _Data_type_count "1H chemical shifts" 275 stop_ loop_ _Revision_date _Revision_keyword _Revision_author _Revision_detail 2008-07-10 revision BMRB 'Updating non-standard residue' 1999-06-14 revision BMRB 'Converted to BMRB NMR-STAR V 2.1 format' 1996-03-25 reformat BMRB 'Converted to the BMRB 1996-03-01 STAR flat-file format' 1995-07-31 original BMRB 'Last release in original BMRB flat-file format' 2008-03-24 original author . stop_ _Original_release_date 2015-07-28 save_ ############################# # Citation for this entry # ############################# save_entry_citation _Saveframe_category entry_citation _Citation_full ; Junius, F. Keith, Weiss, Anthony, King, Glenn F., "The solution structure of the leucine zipper motif of the Jun oncoprotein homodimer," Eur. J. Biochem. 214, 415-424 (1993). ; _Citation_title ; The solution structure of the leucine zipper motif of the Jun oncoprotein homodimer ; _Citation_status published _Citation_type journal _CAS_abstract_code . _MEDLINE_UI_code . _PubMed_ID ? loop_ _Author_ordinal _Author_family_name _Author_given_name _Author_middle_initials _Author_family_title 1 Junius F. Keith . 2 Weiss Anthony . . 3 King Glenn F. . stop_ _Journal_abbreviation 'Eur. J. Biochem.' _Journal_volume 214 _Journal_issue . _Journal_CSD . _Book_chapter_title . _Book_volume . _Book_series . _Book_ISBN . _Conference_state_province . _Conference_abstract_number . _Page_first 415 _Page_last 424 _Year 1993 _Details . save_ ################################## # Molecular system description # ################################## save_system_Jun_leucine_zipper_domain _Saveframe_category molecular_system _Mol_system_name 'Jun leucine zipper domain' _Enzyme_commission_number . loop_ _Mol_system_component_name _Mol_label 'Jun leucine zipper domain' $Jun_leucine_zipper_domain stop_ _System_molecular_weight . _System_oligomer_state ? _System_paramagnetic ? _System_thiol_state . _Database_query_date . _Details . save_ ######################## # Monomeric polymers # ######################## save_Jun_leucine_zipper_domain _Saveframe_category monomeric_polymer _Mol_type polymer _Mol_polymer_class protein _Name_common 'Jun leucine zipper domain' _Molecular_mass . _Mol_thiol_state . _Details . ############################## # Polymer residue sequence # ############################## _Residue_count 44 _Mol_residue_sequence ; XCGGRIARLEEKVKTLKAQN SELASTANMLREQVAQLKQK VMNY ; loop_ _Residue_seq_code _Residue_label 1 ACE 2 CYS 3 GLY 4 GLY 5 ARG 6 ILE 7 ALA 8 ARG 9 LEU 10 GLU 11 GLU 12 LYS 13 VAL 14 LYS 15 THR 16 LEU 17 LYS 18 ALA 19 GLN 20 ASN 21 SER 22 GLU 23 LEU 24 ALA 25 SER 26 THR 27 ALA 28 ASN 29 MET 30 LEU 31 ARG 32 GLU 33 GLN 34 VAL 35 ALA 36 GLN 37 LEU 38 LYS 39 GLN 40 LYS 41 VAL 42 MET 43 ASN 44 TYR stop_ _Sequence_homology_query_date . _Sequence_homology_query_revised_last_date 2015-10-14 loop_ _Database_name _Database_accession_code _Database_entry_mol_name _Sequence_query_to_submitted_percentage _Sequence_subject_length _Sequence_identity _Sequence_positive _Sequence_homology_expectation_value BMRB 17514 LZ-cJun 88.64 42 100.00 100.00 3.96e-16 PDB 1A02 "Structure Of The Dna Binding Domains Of Nfat, Fos And Jun Bound To Dna" 75.00 56 100.00 100.00 6.95e-12 PDB 1FOS "Two Human C-Fos:c-Jun:dna Complexes" 90.91 62 97.50 100.00 6.66e-17 PDB 1JNM "Crystal Structure Of The JunCRE COMPLEX" 90.91 62 97.50 100.00 6.66e-17 PDB 1JUN "Nmr Study Of C-Jun Homodimer" 95.45 44 100.00 100.00 2.02e-19 PDB 1S9K "Crystal Structure Of Human Nfat1 And Fos-Jun On The Il-2 Arre1 Site" 75.00 52 100.00 100.00 1.16e-11 PDB 1T2K "Structure Of The Dna Binding Domains Of Irf3, Atf-2 And Jun Bound To Dna" 88.64 62 100.00 100.00 3.03e-16 PDB 2H7H "Crystal Structure Of The Jun Bzip Homodimer Complexed With Ap-1 Dna" 90.91 62 97.50 100.00 6.66e-17 DBJ BAD98539 "c-jun [Alligator mississippiensis]" 90.91 320 97.50 100.00 8.41e-16 DBJ BAD98540 "c-jun [Pseudemys nelsoni]" 90.91 314 97.50 100.00 8.27e-16 DBJ BAD98541 "c-jun [Crocodylus niloticus]" 90.91 319 97.50 100.00 6.13e-16 DBJ BAE20944 "unnamed protein product [Mus musculus]" 90.91 334 97.50 100.00 8.99e-16 DBJ BAE22389 "unnamed protein product [Mus musculus]" 90.91 334 97.50 100.00 9.47e-16 EMBL CAA31236 "unnamed protein product [Mus musculus]" 90.91 334 97.50 100.00 9.47e-16 EMBL CAA31252 "unnamed protein product [Mus musculus]" 90.91 334 97.50 100.00 1.19e-15 EMBL CAA33553 "unnamed protein product [Coturnix coturnix]" 90.91 313 97.50 100.00 8.98e-16 EMBL CAA35041 "unnamed protein product [Rattus sp.]" 90.91 334 97.50 100.00 1.01e-15 EMBL CAA35084 "unnamed protein product [Rattus norvegicus]" 90.91 334 97.50 100.00 1.01e-15 GB AAA37419 "c-jun protein [Mus musculus]" 90.91 334 97.50 100.00 9.47e-16 GB AAA42416 "jun oncogene, partial [Avian sarcoma virus]" 90.91 340 97.50 100.00 7.92e-16 GB AAA48927 "jun protein [Gallus gallus]" 90.91 310 97.50 100.00 9.11e-16 GB AAA49537 "immediate-early protein [Serinus canaria]" 90.91 314 97.50 100.00 7.40e-16 GB AAA59197 "JUN [Homo sapiens]" 90.91 331 97.50 100.00 8.79e-16 PRF 1404381A "c-jun oncogene" 90.91 330 97.50 100.00 9.06e-16 PRF 1411298A "c-jun gene" 90.91 331 97.50 100.00 9.06e-16 PRF 1411300A "oncogene JUN/AP1" 90.91 334 97.50 100.00 9.47e-16 PRF 2107314A "c-jun gene [Serinus canaria]" 90.91 314 97.50 100.00 7.40e-16 REF NP_001026460 "transcription factor AP-1 [Gallus gallus]" 90.91 310 97.50 100.00 9.11e-16 REF NP_001071295 "transcription factor AP-1 [Bos taurus]" 90.91 303 97.50 100.00 9.52e-16 REF NP_001185876 "transcription factor AP-1 [Oryctolagus cuniculus]" 90.91 337 97.50 100.00 1.11e-15 REF NP_001252779 "transcription factor AP-1 [Macaca mulatta]" 90.91 334 97.50 100.00 9.97e-16 REF NP_001274537 "jun proto-oncogene [Alligator mississippiensis]" 90.91 320 97.50 100.00 8.41e-16 SP O77627 "RecName: Full=Transcription factor AP-1; AltName: Full=Activator protein 1; Short=AP1; AltName: Full=Proto-oncogene c-Jun; AltN" 90.91 335 97.50 100.00 9.68e-16 SP P05411 "RecName: Full=Viral jun-transforming protein; Short=v-Jun" 90.91 287 97.50 100.00 6.31e-16 SP P05412 "RecName: Full=Transcription factor AP-1; AltName: Full=Activator protein 1; Short=AP1; AltName: Full=Proto-oncogene c-Jun; AltN" 90.91 331 97.50 100.00 8.79e-16 SP P05627 "RecName: Full=Transcription factor AP-1; AltName: Full=AH119; AltName: Full=Activator protein 1; Short=AP1; AltName: Full=Proto" 90.91 334 97.50 100.00 9.47e-16 SP P12981 "RecName: Full=Transcription factor AP-1; AltName: Full=Proto-oncogene c-Jun" 90.91 313 97.50 100.00 8.98e-16 TPG DAA31168 "TPA: transcription factor AP-1 [Bos taurus]" 90.91 303 97.50 100.00 9.52e-16 stop_ save_ ###################### # Polymer residues # ###################### save_chem_comp_ACE _Saveframe_category polymer_residue _Mol_type NON-POLYMER _Name_common 'ACETYL GROUP' _BMRB_code ACE _PDB_code ACE _Standard_residue_derivative . _Molecular_mass 44.053 _Mol_paramagnetic . _Details . loop_ _Atom_name _PDB_atom_name _Atom_type _Atom_chirality _Atom_charge _Atom_oxidation_number _Atom_unpaired_electrons C C C . 0 . ? O O O . 0 . ? CH3 CH3 C . 0 . ? H H H . 0 . ? H1 H1 H . 0 . ? H2 H2 H . 0 . ? H3 H3 H . 0 . ? stop_ loop_ _Bond_order _Bond_atom_one_atom_name _Bond_atom_two_atom_name _PDB_bond_atom_one_atom_name _PDB_bond_atom_two_atom_name DOUB C O ? ? SING C CH3 ? ? SING C H ? ? SING CH3 H1 ? ? SING CH3 H2 ? ? SING CH3 H3 ? ? stop_ save_ ######################### # Experimental source # ######################### save_experimental_source _Saveframe_category experimental_source loop_ _Mol_label _Production_method _Host_organism_name_common _Genus _Species _Strain _Vector_name $Jun_leucine_zipper_domain 'not available' . . . . . stop_ save_ ##################################### # Sample contents and methodology # ##################################### ######################## # Sample description # ######################## save_sample_one _Saveframe_category sample _Sample_type solution _Details . loop_ _Mol_label _Concentration_value _Concentration_value_units _Isotopic_labeling . . mM . stop_ save_ ######################### # Experimental detail # ######################### ################################## # NMR Spectrometer definitions # ################################## save_spectrometer_list _Saveframe_category NMR_spectrometer _Manufacturer unknown _Model unknown _Field_strength 0 _Details 'spectrometer information not available' save_ ############################# # NMR applied experiments # ############################# save__1 _Saveframe_category NMR_applied_experiment _Sample_label . save_ ####################### # Sample conditions # ####################### save_sample_condition_set_one _Saveframe_category sample_conditions _Details . loop_ _Variable_type _Variable_value _Variable_value_error _Variable_value_units pH 3.6 . na temperature 310 . K stop_ save_ #################### # NMR parameters # #################### ############################## # Assigned chemical shifts # ############################## ################################ # Chemical shift referencing # ################################ save_chem_shift_reference_par_set_one _Saveframe_category chemical_shift_reference _Details 'The chemical shift reference is not available at this time.' loop_ _Mol_common_name _Atom_type _Atom_isotope_number _Atom_group _Chem_shift_units _Chem_shift_value _Reference_method _Reference_type _External_reference_sample_geometry _External_reference_location _External_reference_axis . H 1 . ppm . . . . . . stop_ save_ ################################### # Assigned chemical shift lists # ################################### ################################################################### # Chemical Shift Ambiguity Index Value Definitions # # # # The values other than 1 are used for those atoms with different # # chemical shifts that cannot be assigned to stereospecific atoms # # or to specific residues or chains. # # # # Index Value Definition # # # # 1 Unique (including isolated methyl protons, # # geminal atoms, and geminal methyl # # groups with identical chemical shifts) # # (e.g. ILE HD11, HD12, HD13 protons) # # 2 Ambiguity of geminal atoms or geminal methyl # # proton groups (e.g. ASP HB2 and HB3 # # protons, LEU CD1 and CD2 carbons, or # # LEU HD11, HD12, HD13 and HD21, HD22, # # HD23 methyl protons) # # 3 Aromatic atoms on opposite sides of # # symmetrical rings (e.g. TYR HE1 and HE2 # # protons) # # 4 Intraresidue ambiguities (e.g. LYS HG and # # HD protons or TRP HZ2 and HZ3 protons) # # 5 Interresidue ambiguities (LYS 12 vs. LYS 27) # # 6 Intermolecular ambiguities (e.g. ASP 31 CA # # in monomer 1 and ASP 31 CA in monomer 2 # # of an asymmetrical homodimer, duplex # # DNA assignments, or other assignments # # that may apply to atoms in one or more # # molecule in the molecular assembly) # # 9 Ambiguous, specific ambiguity not defined # # # ################################################################### save_chemical_shift_assignment_data_set_one _Saveframe_category assigned_chemical_shifts _Details . loop_ _Sample_label $sample_one stop_ _Sample_conditions_label $sample_condition_set_one _Chem_shift_reference_set_label $chem_shift_reference_par_set_one _Mol_system_component_name 'Jun leucine zipper domain' _Text_data_format . _Text_data . loop_ _Atom_shift_assign_ID _Residue_author_seq_code _Residue_seq_code _Residue_label _Atom_name _Atom_type _Chem_shift_value _Chem_shift_value_error _Chem_shift_ambiguity_code 1 . 1 ACE H1 H 2.17 . 1 2 . 2 CYS H H 8.93 . 1 3 . 2 CYS HA H 4.45 . 1 4 . 2 CYS HB2 H 3.15 . 1 5 . 2 CYS HB3 H 3.15 . 1 6 . 3 GLY H H 8.86 . 1 7 . 3 GLY HA2 H 3.8 . 2 8 . 3 GLY HA3 H 3.99 . 2 9 . 4 GLY H H 8.19 . 1 10 . 4 GLY HA2 H 3.96 . 2 11 . 4 GLY HA3 H 4.06 . 2 12 . 5 ARG H H 7.71 . 1 13 . 5 ARG HA H 4.07 . 1 14 . 5 ARG HB2 H 1.89 . 1 15 . 5 ARG HB3 H 1.89 . 1 16 . 5 ARG HG2 H 1.76 . 1 17 . 5 ARG HG3 H 1.76 . 1 18 . 5 ARG HD2 H 3.24 . 1 19 . 5 ARG HD3 H 3.24 . 1 20 . 5 ARG HE H 7.17 . 1 21 . 6 ILE H H 7.94 . 1 22 . 6 ILE HA H 3.59 . 1 23 . 6 ILE HB H 1.97 . 1 24 . 6 ILE HG12 H 1.65 . 2 25 . 6 ILE HG13 H 1 . 2 26 . 6 ILE HG2 H .84 . 1 27 . 6 ILE HD1 H .84 . 1 28 . 7 ALA H H 8.14 . 1 29 . 7 ALA HA H 4.15 . 1 30 . 7 ALA HB H 1.5 . 1 31 . 8 ARG H H 7.69 . 1 32 . 8 ARG HA H 4.14 . 1 33 . 8 ARG HB2 H 1.97 . 1 34 . 8 ARG HB3 H 1.97 . 1 35 . 8 ARG HG2 H 1.87 . 2 36 . 8 ARG HG3 H 1.73 . 2 37 . 8 ARG HD2 H 3.26 . 1 38 . 8 ARG HD3 H 3.26 . 1 39 . 8 ARG HE H 7.27 . 1 40 . 9 LEU H H 7.87 . 1 41 . 9 LEU HA H 4.12 . 1 42 . 9 LEU HB2 H 2.11 . 2 43 . 9 LEU HB3 H 1.35 . 2 44 . 9 LEU HG H 1.85 . 1 45 . 9 LEU HD1 H 1.01 . 2 46 . 9 LEU HD2 H .9 . 2 47 . 10 GLU H H 8.85 . 1 48 . 10 GLU HA H 3.98 . 1 49 . 10 GLU HB2 H 2.28 . 1 50 . 10 GLU HB3 H 2.28 . 1 51 . 10 GLU HG2 H 2.65 . 2 52 . 10 GLU HG3 H 2.36 . 2 53 . 11 GLU H H 7.95 . 1 54 . 11 GLU HA H 4.15 . 1 55 . 11 GLU HB2 H 2.23 . 1 56 . 11 GLU HB3 H 2.23 . 1 57 . 11 GLU HG2 H 2.51 . 1 58 . 11 GLU HG3 H 2.51 . 1 59 . 12 LYS H H 7.74 . 1 60 . 12 LYS HA H 4.15 . 1 61 . 12 LYS HB2 H 2.03 . 1 62 . 12 LYS HB3 H 2.03 . 1 63 . 12 LYS HG2 H 1.64 . 1 64 . 12 LYS HG3 H 1.64 . 1 65 . 12 LYS HD2 H 1.75 . 1 66 . 12 LYS HD3 H 1.75 . 1 67 . 12 LYS HE2 H 2.98 . 1 68 . 12 LYS HE3 H 2.98 . 1 69 . 12 LYS HZ H 7.56 . 1 70 . 13 VAL H H 8.34 . 1 71 . 13 VAL HA H 3.42 . 1 72 . 13 VAL HB H 2.23 . 1 73 . 13 VAL HG1 H 1.03 . 2 74 . 13 VAL HG2 H .89 . 2 75 . 14 LYS H H 7.98 . 1 76 . 14 LYS HA H 3.91 . 1 77 . 14 LYS HB2 H 1.98 . 1 78 . 14 LYS HB3 H 1.98 . 1 79 . 14 LYS HG2 H 1.43 . 1 80 . 14 LYS HG3 H 1.43 . 1 81 . 14 LYS HD2 H 1.71 . 2 82 . 14 LYS HD3 H 1.63 . 2 83 . 14 LYS HE2 H 2.98 . 1 84 . 14 LYS HE3 H 2.98 . 1 85 . 14 LYS HZ H 7.55 . 1 86 . 15 THR H H 8.29 . 1 87 . 15 THR HA H 4.06 . 1 88 . 15 THR HB H 4.33 . 1 89 . 15 THR HG2 H 1.29 . 1 90 . 16 LEU H H 8.51 . 1 91 . 16 LEU HA H 4.1 . 1 92 . 16 LEU HB2 H 2.1 . 2 93 . 16 LEU HB3 H 1.29 . 2 94 . 16 LEU HG H 1.84 . 1 95 . 16 LEU HD1 H .96 . 2 96 . 16 LEU HD2 H .89 . 2 97 . 17 LYS H H 8.88 . 1 98 . 17 LYS HA H 3.99 . 1 99 . 17 LYS HB2 H 1.94 . 1 100 . 17 LYS HB3 H 1.94 . 1 101 . 17 LYS HG2 H 1.47 . 1 102 . 17 LYS HG3 H 1.47 . 1 103 . 17 LYS HD2 H 1.73 . 2 104 . 17 LYS HD3 H 1.61 . 2 105 . 17 LYS HE2 H 2.98 . 1 106 . 17 LYS HE3 H 2.98 . 1 107 . 17 LYS HZ H 7.56 . 1 108 . 18 ALA H H 7.77 . 1 109 . 18 ALA HA H 4.26 . 1 110 . 18 ALA HB H 1.6 . 1 111 . 19 GLN H H 8.3 . 1 112 . 19 GLN HA H 4.11 . 1 113 . 19 GLN HB2 H 2.21 . 2 114 . 19 GLN HB3 H 2.04 . 2 115 . 19 GLN HG2 H 2.64 . 2 116 . 19 GLN HG3 H 2.38 . 2 117 . 19 GLN HE21 H 7.3 . 2 118 . 19 GLN HE22 H 6.62 . 2 119 . 20 ASN H H 8.8 . 1 120 . 20 ASN HA H 4.31 . 1 121 . 20 ASN HB2 H 3.28 . 2 122 . 20 ASN HB3 H 2.8 . 2 123 . 20 ASN HD21 H 7.67 . 2 124 . 20 ASN HD22 H 6.75 . 2 125 . 21 SER H H 8.15 . 1 126 . 21 SER HA H 4.27 . 1 127 . 21 SER HB2 H 4.07 . 1 128 . 21 SER HB3 H 4.07 . 1 129 . 22 GLU H H 7.81 . 1 130 . 22 GLU HA H 4.22 . 1 131 . 22 GLU HB2 H 2.25 . 1 132 . 22 GLU HB3 H 2.25 . 1 133 . 22 GLU HG2 H 2.59 . 2 134 . 22 GLU HG3 H 2.48 . 2 135 . 23 LEU H H 8.66 . 1 136 . 23 LEU HA H 4.04 . 1 137 . 23 LEU HB2 H 2.05 . 2 138 . 23 LEU HB3 H 1.3 . 2 139 . 23 LEU HG H 1.85 . 1 140 . 23 LEU HD1 H .95 . 2 141 . 23 LEU HD2 H .87 . 2 142 . 24 ALA H H 8.71 . 1 143 . 24 ALA HA H 4.12 . 1 144 . 24 ALA HB H 1.54 . 1 145 . 25 SER H H 8.01 . 1 146 . 25 SER HA H 4.33 . 1 147 . 25 SER HB2 H 4.1 . 1 148 . 25 SER HB3 H 4.1 . 1 149 . 26 THR H H 8.39 . 1 150 . 26 THR HA H 4 . 1 151 . 26 THR HB H 4.36 . 1 152 . 26 THR HG2 H 1.25 . 1 153 . 27 ALA H H 8.57 . 1 154 . 27 ALA HA H 3.96 . 1 155 . 27 ALA HB H 1.46 . 1 156 . 28 ASN H H 8.08 . 1 157 . 28 ASN HA H 4.45 . 1 158 . 28 ASN HB2 H 2.95 . 1 159 . 28 ASN HB3 H 2.95 . 1 160 . 28 ASN HD21 H 7.63 . 2 161 . 28 ASN HD22 H 6.89 . 2 162 . 29 MET H H 8.07 . 1 163 . 29 MET HA H 4.23 . 1 164 . 29 MET HB2 H 2.32 . 1 165 . 29 MET HB3 H 2.32 . 1 166 . 29 MET HG2 H 2.8 . 2 167 . 29 MET HG3 H 2.61 . 2 168 . 30 LEU H H 8.43 . 1 169 . 30 LEU HA H 4.13 . 1 170 . 30 LEU HB2 H 2.05 . 2 171 . 30 LEU HB3 H 1.3 . 2 172 . 30 LEU HG H 1.92 . 1 173 . 30 LEU HD1 H .93 . 2 174 . 30 LEU HD2 H .9 . 2 175 . 31 ARG H H 8.62 . 1 176 . 31 ARG HA H 3.87 . 1 177 . 31 ARG HB2 H 2.05 . 2 178 . 31 ARG HB3 H 1.92 . 2 179 . 31 ARG HG2 H 1.65 . 1 180 . 31 ARG HG3 H 1.65 . 1 181 . 31 ARG HD2 H 3.24 . 1 182 . 31 ARG HD3 H 3.24 . 1 183 . 31 ARG HE H 7.29 . 1 184 . 32 GLU H H 7.74 . 1 185 . 32 GLU HA H 4.2 . 1 186 . 32 GLU HB2 H 2.31 . 1 187 . 32 GLU HB3 H 2.31 . 1 188 . 32 GLU HG2 H 2.63 . 2 189 . 32 GLU HG3 H 2.51 . 2 190 . 33 GLN H H 7.98 . 1 191 . 33 GLN HA H 4.1 . 1 192 . 33 GLN HB2 H 2.15 . 1 193 . 33 GLN HB3 H 2.15 . 1 194 . 33 GLN HG2 H 2.35 . 1 195 . 33 GLN HG3 H 2.35 . 1 196 . 33 GLN HE21 H 7.17 . 2 197 . 33 GLN HE22 H 6.6 . 2 198 . 34 VAL H H 8.55 . 1 199 . 34 VAL HA H 3.42 . 1 200 . 34 VAL HB H 2.15 . 1 201 . 34 VAL HG1 H 1.07 . 2 202 . 34 VAL HG2 H .88 . 2 203 . 35 ALA H H 7.7 . 1 204 . 35 ALA HA H 4.02 . 1 205 . 35 ALA HB H 1.53 . 1 206 . 36 GLN H H 7.96 . 1 207 . 36 GLN HA H 4.08 . 1 208 . 36 GLN HB2 H 2.23 . 1 209 . 36 GLN HB3 H 2.23 . 1 210 . 36 GLN HG2 H 2.62 . 2 211 . 36 GLN HG3 H 2.41 . 2 212 . 36 GLN HE21 H 7.34 . 2 213 . 36 GLN HE22 H 6.76 . 2 214 . 37 LEU H H 8.33 . 1 215 . 37 LEU HA H 4.07 . 1 216 . 37 LEU HB2 H 2.02 . 2 217 . 37 LEU HB3 H 1.34 . 2 218 . 37 LEU HG H 1.89 . 1 219 . 37 LEU HD1 H .95 . 2 220 . 37 LEU HD2 H .85 . 2 221 . 38 LYS H H 8.6 . 1 222 . 38 LYS HA H 3.93 . 1 223 . 38 LYS HB2 H 1.87 . 1 224 . 38 LYS HB3 H 1.87 . 1 225 . 38 LYS HG2 H 1.36 . 1 226 . 38 LYS HG3 H 1.36 . 1 227 . 38 LYS HD2 H 1.65 . 1 228 . 38 LYS HD3 H 1.65 . 1 229 . 38 LYS HE2 H 2.86 . 1 230 . 38 LYS HE3 H 2.86 . 1 231 . 38 LYS HZ H 7.55 . 1 232 . 39 GLN H H 7.4 . 1 233 . 39 GLN HA H 4.13 . 1 234 . 39 GLN HB2 H 2.18 . 1 235 . 39 GLN HB3 H 2.18 . 1 236 . 39 GLN HG2 H 2.54 . 2 237 . 39 GLN HG3 H 2.43 . 2 238 . 39 GLN HE21 H 7.36 . 2 239 . 39 GLN HE22 H 6.78 . 2 240 . 40 LYS H H 7.63 . 1 241 . 40 LYS HA H 4.25 . 1 242 . 40 LYS HB2 H 1.98 . 1 243 . 40 LYS HB3 H 1.98 . 1 244 . 40 LYS HG2 H 1.59 . 2 245 . 40 LYS HG3 H 1.5 . 2 246 . 40 LYS HD2 H 1.69 . 1 247 . 40 LYS HD3 H 1.69 . 1 248 . 40 LYS HE2 H 2.99 . 1 249 . 40 LYS HE3 H 2.99 . 1 250 . 40 LYS HZ H 7.56 . 1 251 . 41 VAL H H 7.73 . 1 252 . 41 VAL HA H 3.99 . 1 253 . 41 VAL HB H 2.13 . 1 254 . 41 VAL HG1 H .98 . 2 255 . 41 VAL HG2 H .92 . 2 256 . 42 MET H H 7.94 . 1 257 . 42 MET HA H 4.4 . 1 258 . 42 MET HB2 H 2.01 . 1 259 . 42 MET HB3 H 2.01 . 1 260 . 42 MET HG2 H 2.58 . 2 261 . 42 MET HG3 H 2.52 . 2 262 . 43 ASN H H 8.02 . 1 263 . 43 ASN HA H 4.71 . 1 264 . 43 ASN HB2 H 2.81 . 2 265 . 43 ASN HB3 H 2.67 . 2 266 . 43 ASN HD21 H 7.46 . 2 267 . 43 ASN HD22 H 6.79 . 2 268 . 44 TYR H H 7.67 . 1 269 . 44 TYR HA H 4.46 . 1 270 . 44 TYR HB2 H 3.07 . 2 271 . 44 TYR HB3 H 2.94 . 2 272 . 44 TYR HD1 H 7.09 . 1 273 . 44 TYR HD2 H 7.09 . 1 274 . 44 TYR HE1 H 6.81 . 1 275 . 44 TYR HE2 H 6.81 . 1 stop_ save_