data_16756 ####################### # Entry information # ####################### save_entry_information _Entry.Sf_category entry_information _Entry.Sf_framecode entry_information _Entry.ID 16756 _Entry.Title ; Structure of a regulatory complex infolving the Ab1 SH3 domain, the Crk SH2 domain and a Crk-derived phosphopeptide ; _Entry.Type macromolecule _Entry.Version_type original _Entry.Submission_date 2010-03-03 _Entry.Accession_date 2010-03-03 _Entry.Last_release_date 2010-03-24 _Entry.Original_release_date 2010-03-24 _Entry.Origination author _Entry.NMR_STAR_version 3.1.1.61 _Entry.Original_NMR_STAR_version 3.0.9.13 _Entry.Experimental_method NMR _Entry.Experimental_method_subtype solution _Entry.Details . _Entry.BMRB_internal_directory_name . loop_ _Entry_author.Ordinal _Entry_author.Given_name _Entry_author.Family_name _Entry_author.First_initial _Entry_author.Middle_initials _Entry_author.Family_title _Entry_author.Entry_ID 1 Logan Donaldson . W. . 16756 2 Gerald Gish . . . 16756 3 Tony Pawson . . . 16756 4 Lewis Kay . E. . 16756 5 Julie Forman-Kay . D. . 16756 stop_ loop_ _Data_set.Type _Data_set.Count _Data_set.Entry_ID binding_constants 1 16756 stop_ loop_ _Datum.Type _Datum.Count _Datum.Entry_ID 'binding constants' 6 16756 stop_ loop_ _Release.Release_number _Release.Format_type _Release.Format_version _Release.Date _Release.Submission_date _Release.Type _Release.Author _Release.Detail _Release.Entry_ID 1 . . 2010-03-24 2010-03-03 original author . 16756 stop_ save_ ############### # Citations # ############### save_entry_citation _Citation.Sf_category citations _Citation.Sf_framecode entry_citation _Citation.Entry_ID 16756 _Citation.ID 1 _Citation.Class 'entry citation' _Citation.CAS_abstract_code . _Citation.MEDLINE_UI_code . _Citation.DOI . _Citation.PubMed_ID 12384576 _Citation.Full_citation . _Citation.Title 'Structure of a regulatory complex involving the Abl SH3 domain, the Crk SH2 domain, and a Crk-derived phosphopeptide' _Citation.Status published _Citation.Type journal _Citation.Journal_abbrev 'Proc. Natl. Acad. Sci. U.S.A.' _Citation.Journal_name_full . _Citation.Journal_volume 99 _Citation.Journal_issue 22 _Citation.Journal_ASTM . _Citation.Journal_ISSN . _Citation.Journal_CSD . _Citation.Book_title . _Citation.Book_chapter_title . _Citation.Book_volume . _Citation.Book_series . _Citation.Book_publisher . _Citation.Book_publisher_city . _Citation.Book_ISBN . _Citation.Conference_title . _Citation.Conference_site . _Citation.Conference_state_province . _Citation.Conference_country . _Citation.Conference_start_date . _Citation.Conference_end_date . _Citation.Conference_abstract_number . _Citation.Thesis_institution . _Citation.Thesis_institution_city . _Citation.Thesis_institution_country . _Citation.WWW_URL . _Citation.Page_first 14053 _Citation.Page_last 14058 _Citation.Year 2002 _Citation.Details . loop_ _Citation_author.Ordinal _Citation_author.Given_name _Citation_author.Family_name _Citation_author.First_initial _Citation_author.Middle_initials _Citation_author.Family_title _Citation_author.Entry_ID _Citation_author.Citation_ID 1 Logan Donaldson . W. . 16756 1 2 Gerald Gish . . . 16756 1 3 Tony Pawson . . . 16756 1 4 Lewis Kay . E. . 16756 1 5 Julie Forman-Kay . D. . 16756 1 stop_ save_ ############################################# # Molecular system (assembly) description # ############################################# save_assembly _Assembly.Sf_category assembly _Assembly.Sf_framecode assembly _Assembly.Entry_ID 16756 _Assembly.ID 1 _Assembly.Name 'Abl/Crk/Crk pY221 complex' _Assembly.BMRB_code . _Assembly.Number_of_components 3 _Assembly.Organic_ligands . _Assembly.Metal_ions . _Assembly.Non_standard_bonds no _Assembly.Ambiguous_conformational_states . _Assembly.Ambiguous_chem_comp_sites . _Assembly.Molecules_in_chemical_exchange . _Assembly.Paramagnetic no _Assembly.Thiol_state . _Assembly.Molecular_mass . _Assembly.Enzyme_commission_number . _Assembly.Details . _Assembly.DB_query_date . _Assembly.DB_query_revised_last_date . loop_ _Entity_assembly.ID _Entity_assembly.Entity_assembly_name _Entity_assembly.Entity_ID _Entity_assembly.Entity_label _Entity_assembly.Asym_ID _Entity_assembly.PDB_chain_ID _Entity_assembly.Experimental_data_reported _Entity_assembly.Physical_state _Entity_assembly.Conformational_isomer _Entity_assembly.Chemical_exchange_state _Entity_assembly.Magnetic_equivalence_group_code _Entity_assembly.Role _Entity_assembly.Details _Entity_assembly.Entry_ID _Entity_assembly.Assembly_ID 1 Abl 1 $Abl A . yes native no no . . . 16756 1 2 Crk 2 $Crk B . yes native no no . . . 16756 1 3 'Crk pY221' 3 $Crk_pY221 C . yes native no no . . . 16756 1 stop_ save_ #################################### # Biological polymers and ligands # #################################### save_Abl _Entity.Sf_category entity _Entity.Sf_framecode Abl _Entity.Entry_ID 16756 _Entity.ID 1 _Entity.BMRB_code . _Entity.Name Abl _Entity.Type polymer _Entity.Polymer_common_type . _Entity.Polymer_type polypeptide(L) _Entity.Polymer_type_details . _Entity.Polymer_strand_ID . _Entity.Polymer_seq_one_letter_code_can . _Entity.Polymer_seq_one_letter_code ; DPNLFVALYDFVASGDNTLS ITKGEKLRVLGYNHNGEWCE AQTKNGQGWVPSNYITPVNS K ; _Entity.Target_identifier . _Entity.Polymer_author_defined_seq . _Entity.Polymer_author_seq_details . _Entity.Ambiguous_conformational_states no _Entity.Ambiguous_chem_comp_sites no _Entity.Nstd_monomer no _Entity.Nstd_chirality no _Entity.Nstd_linkage no _Entity.Nonpolymer_comp_ID . _Entity.Nonpolymer_comp_label . _Entity.Number_of_monomers 61 _Entity.Number_of_nonpolymer_components . _Entity.Paramagnetic no _Entity.Thiol_state 'not present' _Entity.Src_method . _Entity.Parent_entity_ID . _Entity.Fragment 'SH3 Domain' _Entity.Mutation . _Entity.EC_number . _Entity.Calc_isoelectric_point . _Entity.Formula_weight . _Entity.Formula_weight_exptl . _Entity.Formula_weight_exptl_meth . _Entity.Details . _Entity.DB_query_date . _Entity.DB_query_revised_last_date 2015-11-25 loop_ _Entity_db_link.Ordinal _Entity_db_link.Author_supplied _Entity_db_link.Database_code _Entity_db_link.Accession_code _Entity_db_link.Entry_mol_code _Entity_db_link.Entry_mol_name _Entity_db_link.Entry_experimental_method _Entity_db_link.Entry_structure_resolution _Entity_db_link.Entry_relation_type _Entity_db_link.Entry_details _Entity_db_link.Chimera_segment_ID _Entity_db_link.Seq_query_to_submitted_percent _Entity_db_link.Seq_subject_length _Entity_db_link.Seq_identity _Entity_db_link.Seq_positive _Entity_db_link.Seq_homology_expectation_val _Entity_db_link.Seq_align_begin _Entity_db_link.Seq_align_end _Entity_db_link.Seq_difference_details _Entity_db_link.Seq_alignment_details _Entity_db_link.Entry_ID _Entity_db_link.Entity_ID 1 no PDB 1ABO . "Crystal Structure Of The Complex Of The Abl Tyrosine Kinase Sh3 Domain With 3bp-1 Synthetic Peptide" . . . . . 98.36 62 100.00 100.00 5.00e-36 . . . . 16756 1 2 no PDB 1ABQ . "Crystal Structure Of The Unliganded Abl Tyrosine Kinase Sh3 Domain" . . . . . 98.36 62 100.00 100.00 5.00e-36 . . . . 16756 1 3 no PDB 1BBZ . "Crystal Structure Of The Abl-Sh3 Domain Complexed With A Designed High-Affinity Peptide Ligand: Implications For Sh3-Ligand Int" . . . . . 95.08 58 100.00 100.00 4.04e-34 . . . . 16756 1 4 no PDB 1JU5 . "Ternary Complex Of An Crk Sh2 Domain, Crk-Derived Phophopeptide, And Abl Sh3 Domain By Nmr Spectroscopy" . . . . . 100.00 61 100.00 100.00 1.14e-36 . . . . 16756 1 5 no PDB 1OPK . "Structural Basis For The Auto-Inhibition Of C-Abl Tyrosine Kinase" . . . . . 98.36 495 100.00 100.00 1.28e-33 . . . . 16756 1 6 no PDB 1OPL . "Structural Basis For The Auto-Inhibition Of C-Abl Tyrosine Kinase" . . . . . 98.36 537 100.00 100.00 1.75e-33 . . . . 16756 1 7 no PDB 2ABL . "Sh3-Sh2 Domain Fragment Of Human Bcr-Abl Tyrosine Kinase" . . . . . 98.36 163 100.00 100.00 8.88e-36 . . . . 16756 1 8 no PDB 2FO0 . "Organization Of The Sh3-Sh2 Unit In Active And Inactive Forms Of The C-Abl Tyrosine Kinase" . . . . . 98.36 495 100.00 100.00 1.41e-33 . . . . 16756 1 9 no PDB 2O88 . "Crystal Structure Of The N114a Mutant Of Abl-Sh3 Domain Complexed With A Designed High-Affinity Peptide Ligand: Implications Fo" . . . . . 95.08 58 98.28 98.28 2.95e-33 . . . . 16756 1 10 no PDB 3EG0 . "Crystal Structure Of The N114t Mutant Of Abl-Sh3 Domain" . . . . . 98.36 63 98.33 98.33 2.43e-35 . . . . 16756 1 11 no PDB 3EG1 . "Crystal Structure Of The N114q Mutant Of Abl-Sh3 Domain Complexed With A Designed High-Affinity Peptide Ligand: Implications Fo" . . . . . 98.36 63 98.33 98.33 2.45e-35 . . . . 16756 1 12 no PDB 3EG2 . "Crystal Structure Of The N114q Mutant Of Abl-Sh3 Domain" . . . . . 98.36 63 98.33 98.33 2.45e-35 . . . . 16756 1 13 no PDB 3EG3 . "Crystal Structure Of The N114a Mutant Of Abl-sh3 Domain" . . . . . 98.36 63 98.33 98.33 3.67e-35 . . . . 16756 1 14 no PDB 3EGU . "Crystal Structure Of The N114a Mutant Of Abl-Sh3 Domain" . . . . . 98.36 63 98.33 98.33 3.67e-35 . . . . 16756 1 15 no PDB 4J9D . "Crystal Structure Of The N114a Mutant Of The Abl-sh3 Domain Complexed With The High Affinity Peptide P0" . . . . . 98.36 63 98.33 98.33 3.67e-35 . . . . 16756 1 16 no PDB 4J9E . "Crystal Structure Of The N114a Mutant Of The Abl-sh3 Domain Complexed With The High Affinity Peptide P17" . . . . . 98.36 63 98.33 98.33 3.67e-35 . . . . 16756 1 17 no PDB 4J9F . "Crystal Structure Of The Abl-sh3 Domain Complexed With The High Affinity Peptide P0" . . . . . 98.36 63 100.00 100.00 4.80e-36 . . . . 16756 1 18 no PDB 4J9G . "Crystal Structure Of The Abl-sh3 Domain Complexed With The Designed High-affinity Peptide Ligand P7 At Ph7" . . . . . 98.36 63 100.00 100.00 4.80e-36 . . . . 16756 1 19 no PDB 4J9H . "Crystal Structure Of The Abl-sh3 Domain Complexed With The Designed High-affinity Peptide Ligand P7 At Ph 8" . . . . . 98.36 63 100.00 100.00 4.80e-36 . . . . 16756 1 20 no PDB 4J9I . "Crystal Structure Of The Abl-sh3 Domain Complexed With The Designed High-affinity Peptide Ligand P17" . . . . . 98.36 63 100.00 100.00 4.80e-36 . . . . 16756 1 21 no PDB 4JJB . "Crystal Structure Of The Abl-sh3 Domain At Ph3" . . . . . 98.36 63 100.00 100.00 4.80e-36 . . . . 16756 1 22 no PDB 4JJC . "Crystal Structure Of The Abl-sh3 Domain At Ph5" . . . . . 98.36 63 100.00 100.00 4.80e-36 . . . . 16756 1 23 no PDB 4JJD . "Crystal Structure Of The N114a Abl-sh3 Domain Mutant At Ph4" . . . . . 98.36 63 98.33 98.33 3.67e-35 . . . . 16756 1 24 no DBJ BAC41088 . "unnamed protein product [Mus musculus]" . . . . . 98.36 1123 100.00 100.00 1.18e-33 . . . . 16756 1 25 no DBJ BAD92693 . "v-abl Abelson murine leukemia viral oncogene homolog 1 isoform b variant [Homo sapiens]" . . . . . 98.36 1167 100.00 100.00 2.17e-33 . . . . 16756 1 26 no DBJ BAG10808 . "proto-oncogene tyrosine-protein kinase ABL1 [synthetic construct]" . . . . . 98.36 1149 100.00 100.00 1.98e-33 . . . . 16756 1 27 no EMBL CAA10376 . "bcr-abl1 e14a2 chimeric protein [Homo sapiens]" . . . . . 98.36 332 100.00 100.00 8.99e-35 . . . . 16756 1 28 no EMBL CAA10377 . "bcr-abl1 e13a2 chimeric protein [Homo sapiens]" . . . . . 98.36 307 100.00 100.00 5.27e-35 . . . . 16756 1 29 no EMBL CAA34438 . "unnamed protein product [Homo sapiens]" . . . . . 98.36 1130 100.00 100.00 1.74e-33 . . . . 16756 1 30 no EMBL CAF99203 . "unnamed protein product, partial [Tetraodon nigroviridis]" . . . . . 98.36 1465 100.00 100.00 1.16e-33 . . . . 16756 1 31 no EMBL CAM33012 . "bcr-abl1 e6a2 chimeric protein [Homo sapiens]" . . . . . 98.36 585 100.00 100.00 9.22e-34 . . . . 16756 1 32 no GB AAA35593 . "bcr/c-abl oncogene protein, partial [Homo sapiens]" . . . . . 98.36 144 98.33 98.33 4.79e-34 . . . . 16756 1 33 no GB AAA35697 . "bcr/c-abl oncogene protein, partial [Homo sapiens]" . . . . . 98.36 156 100.00 100.00 1.69e-35 . . . . 16756 1 34 no GB AAA37135 . "c-abl-protein type I, partial [Mus musculus domesticus]" . . . . . 95.08 119 100.00 100.00 9.09e-35 . . . . 16756 1 35 no GB AAA37136 . "c-abl-protein type II, partial [Mus musculus domesticus]" . . . . . 95.08 113 100.00 100.00 8.39e-35 . . . . 16756 1 36 no GB AAA37137 . "c-abl-protein type III, partial [Mus musculus domesticus]" . . . . . 95.08 114 100.00 100.00 1.53e-34 . . . . 16756 1 37 no PIR B24773 . "protein-tyrosine kinase (EC 2.7.1.112) abl type II - mouse (fragment)" . . . . . 93.44 112 100.00 100.00 3.97e-34 . . . . 16756 1 38 no PIR C24773 . "protein-tyrosine kinase (EC 2.7.1.112) abl type III - mouse (fragment)" . . . . . 93.44 113 100.00 100.00 6.79e-34 . . . . 16756 1 39 no PIR D24773 . "protein-tyrosine kinase (EC 2.7.1.112) abl type IV - mouse (fragment)" . . . . . 93.44 137 100.00 100.00 1.15e-33 . . . . 16756 1 40 no PRF 1107272A . "abl gene" . . . . . 88.52 164 100.00 100.00 3.25e-31 . . . . 16756 1 41 no PRF 1107272B . "abl gene" . . . . . 88.52 285 100.00 100.00 9.08e-31 . . . . 16756 1 42 no REF NP_001094320 . "tyrosine-protein kinase ABL1 [Rattus norvegicus]" . . . . . 98.36 1143 100.00 100.00 1.60e-33 . . . . 16756 1 43 no REF NP_001106174 . "tyrosine-protein kinase ABL1 isoform a [Mus musculus]" . . . . . 98.36 1142 100.00 100.00 1.21e-33 . . . . 16756 1 44 no REF NP_001193789 . "tyrosine-protein kinase ABL1 [Bos taurus]" . . . . . 98.36 1151 100.00 100.00 1.78e-33 . . . . 16756 1 45 no REF NP_001269974 . "tyrosine-protein kinase ABL1 isoform c [Mus musculus]" . . . . . 98.36 1118 100.00 100.00 1.20e-33 . . . . 16756 1 46 no REF NP_001269975 . "tyrosine-protein kinase ABL1 isoform d [Mus musculus]" . . . . . 98.36 1117 100.00 100.00 1.08e-33 . . . . 16756 1 47 no SP P00519 . "RecName: Full=Tyrosine-protein kinase ABL1; AltName: Full=Abelson murine leukemia viral oncogene homolog 1; AltName: Full=Abels" . . . . . 98.36 1130 100.00 100.00 1.74e-33 . . . . 16756 1 48 no SP P00520 . "RecName: Full=Tyrosine-protein kinase ABL1; AltName: Full=Abelson murine leukemia viral oncogene homolog 1; AltName: Full=Abels" . . . . . 98.36 1123 100.00 100.00 1.18e-33 . . . . 16756 1 49 no SP P10447 . "RecName: Full=Tyrosine-protein kinase transforming protein Abl; AltName: Full=V-abl" . . . . . 98.36 439 100.00 100.00 1.48e-33 . . . . 16756 1 50 no TPG DAA24240 . "TPA: arg tyrosine kinase-like [Bos taurus]" . . . . . 98.36 1151 100.00 100.00 1.78e-33 . . . . 16756 1 stop_ loop_ _Entity_comp_index.ID _Entity_comp_index.Auth_seq_ID _Entity_comp_index.Comp_ID _Entity_comp_index.Comp_label _Entity_comp_index.Entry_ID _Entity_comp_index.Entity_ID 1 . ASP . 16756 1 2 . PRO . 16756 1 3 . ASN . 16756 1 4 . LEU . 16756 1 5 . PHE . 16756 1 6 . VAL . 16756 1 7 . ALA . 16756 1 8 . LEU . 16756 1 9 . TYR . 16756 1 10 . ASP . 16756 1 11 . PHE . 16756 1 12 . VAL . 16756 1 13 . ALA . 16756 1 14 . SER . 16756 1 15 . GLY . 16756 1 16 . ASP . 16756 1 17 . ASN . 16756 1 18 . THR . 16756 1 19 . LEU . 16756 1 20 . SER . 16756 1 21 . ILE . 16756 1 22 . THR . 16756 1 23 . LYS . 16756 1 24 . GLY . 16756 1 25 . GLU . 16756 1 26 . LYS . 16756 1 27 . LEU . 16756 1 28 . ARG . 16756 1 29 . VAL . 16756 1 30 . LEU . 16756 1 31 . GLY . 16756 1 32 . TYR . 16756 1 33 . ASN . 16756 1 34 . HIS . 16756 1 35 . ASN . 16756 1 36 . GLY . 16756 1 37 . GLU . 16756 1 38 . TRP . 16756 1 39 . CYS . 16756 1 40 . GLU . 16756 1 41 . ALA . 16756 1 42 . GLN . 16756 1 43 . THR . 16756 1 44 . LYS . 16756 1 45 . ASN . 16756 1 46 . GLY . 16756 1 47 . GLN . 16756 1 48 . GLY . 16756 1 49 . TRP . 16756 1 50 . VAL . 16756 1 51 . PRO . 16756 1 52 . SER . 16756 1 53 . ASN . 16756 1 54 . TYR . 16756 1 55 . ILE . 16756 1 56 . THR . 16756 1 57 . PRO . 16756 1 58 . VAL . 16756 1 59 . ASN . 16756 1 60 . SER . 16756 1 61 . LYS . 16756 1 stop_ loop_ _Entity_poly_seq.Hetero _Entity_poly_seq.Mon_ID _Entity_poly_seq.Num _Entity_poly_seq.Comp_index_ID _Entity_poly_seq.Entry_ID _Entity_poly_seq.Entity_ID . ASP 1 1 16756 1 . PRO 2 2 16756 1 . ASN 3 3 16756 1 . LEU 4 4 16756 1 . PHE 5 5 16756 1 . VAL 6 6 16756 1 . ALA 7 7 16756 1 . LEU 8 8 16756 1 . TYR 9 9 16756 1 . ASP 10 10 16756 1 . PHE 11 11 16756 1 . VAL 12 12 16756 1 . ALA 13 13 16756 1 . SER 14 14 16756 1 . GLY 15 15 16756 1 . ASP 16 16 16756 1 . ASN 17 17 16756 1 . THR 18 18 16756 1 . LEU 19 19 16756 1 . SER 20 20 16756 1 . ILE 21 21 16756 1 . THR 22 22 16756 1 . LYS 23 23 16756 1 . GLY 24 24 16756 1 . GLU 25 25 16756 1 . LYS 26 26 16756 1 . LEU 27 27 16756 1 . ARG 28 28 16756 1 . VAL 29 29 16756 1 . LEU 30 30 16756 1 . GLY 31 31 16756 1 . TYR 32 32 16756 1 . ASN 33 33 16756 1 . HIS 34 34 16756 1 . ASN 35 35 16756 1 . GLY 36 36 16756 1 . GLU 37 37 16756 1 . TRP 38 38 16756 1 . CYS 39 39 16756 1 . GLU 40 40 16756 1 . ALA 41 41 16756 1 . GLN 42 42 16756 1 . THR 43 43 16756 1 . LYS 44 44 16756 1 . ASN 45 45 16756 1 . GLY 46 46 16756 1 . GLN 47 47 16756 1 . GLY 48 48 16756 1 . TRP 49 49 16756 1 . VAL 50 50 16756 1 . PRO 51 51 16756 1 . SER 52 52 16756 1 . ASN 53 53 16756 1 . TYR 54 54 16756 1 . ILE 55 55 16756 1 . THR 56 56 16756 1 . PRO 57 57 16756 1 . VAL 58 58 16756 1 . ASN 59 59 16756 1 . SER 60 60 16756 1 . LYS 61 61 16756 1 stop_ save_ save_Crk _Entity.Sf_category entity _Entity.Sf_framecode Crk _Entity.Entry_ID 16756 _Entity.ID 2 _Entity.BMRB_code . _Entity.Name Crk _Entity.Type polymer _Entity.Polymer_common_type . _Entity.Polymer_type polypeptide(L) _Entity.Polymer_type_details . _Entity.Polymer_strand_ID . _Entity.Polymer_seq_one_letter_code_can . _Entity.Polymer_seq_one_letter_code ; SWYWGRLSRQEAVALLQGQR HGVFLVRDSSTSPGDYVLSV SENSRVSHYIINSSGPRPPV PPSPAQPPPGVSPSRLRIGD QEFDSLPALLEFYKIHYLDT TTLIPVSR ; _Entity.Target_identifier . _Entity.Polymer_author_defined_seq . _Entity.Polymer_author_seq_details . _Entity.Ambiguous_conformational_states no _Entity.Ambiguous_chem_comp_sites no _Entity.Nstd_monomer no _Entity.Nstd_chirality no _Entity.Nstd_linkage no _Entity.Nonpolymer_comp_ID . _Entity.Nonpolymer_comp_label . _Entity.Number_of_monomers 108 _Entity.Number_of_nonpolymer_components . _Entity.Paramagnetic no _Entity.Thiol_state 'not present' _Entity.Src_method . _Entity.Parent_entity_ID . _Entity.Fragment 'SH2 Domain' _Entity.Mutation . _Entity.EC_number . _Entity.Calc_isoelectric_point . _Entity.Formula_weight . _Entity.Formula_weight_exptl . _Entity.Formula_weight_exptl_meth . _Entity.Details . _Entity.DB_query_date . _Entity.DB_query_revised_last_date 2015-01-30 loop_ _Entity_db_link.Ordinal _Entity_db_link.Author_supplied _Entity_db_link.Database_code _Entity_db_link.Accession_code _Entity_db_link.Entry_mol_code _Entity_db_link.Entry_mol_name _Entity_db_link.Entry_experimental_method _Entity_db_link.Entry_structure_resolution _Entity_db_link.Entry_relation_type _Entity_db_link.Entry_details _Entity_db_link.Chimera_segment_ID _Entity_db_link.Seq_query_to_submitted_percent _Entity_db_link.Seq_subject_length _Entity_db_link.Seq_identity _Entity_db_link.Seq_positive _Entity_db_link.Seq_homology_expectation_val _Entity_db_link.Seq_align_begin _Entity_db_link.Seq_align_end _Entity_db_link.Seq_difference_details _Entity_db_link.Seq_alignment_details _Entity_db_link.Entry_ID _Entity_db_link.Entity_ID 1 no PDB 1JU5 . "Ternary Complex Of An Crk Sh2 Domain, Crk-Derived Phophopeptide, And Abl Sh3 Domain By Nmr Spectroscopy" . . . . . 100.93 109 99.08 99.08 7.74e-68 . . . . 16756 2 2 no PDB 2DVJ . "Phosphorylated Crk-Ii" . . . . . 100.93 230 99.08 99.08 6.05e-67 . . . . 16756 2 3 no PDB 2EYV . "Sh2 Domain Of Ct10-Regulated Kinase" . . . . . 100.93 124 99.08 99.08 4.35e-68 . . . . 16756 2 4 no PDB 2EYY . "Ct10-Regulated Kinase Isoform I" . . . . . 100.93 204 99.08 99.08 1.46e-67 . . . . 16756 2 5 no PDB 2EYZ . "Ct10-Regulated Kinase Isoform Ii" . . . . . 100.93 304 99.08 99.08 3.74e-66 . . . . 16756 2 6 no DBJ BAA01505 . "CRK-II [Homo sapiens]" . . . . . 100.93 304 98.17 98.17 3.66e-65 . . . . 16756 2 7 no DBJ BAA07924 . "CRK-II [Rattus sp.]" . . . . . 100.93 304 99.08 99.08 3.74e-66 . . . . 16756 2 8 no DBJ BAB61871 . "Picchu-236 [synthetic construct]" . . . . . 100.93 716 99.08 99.08 4.14e-64 . . . . 16756 2 9 no DBJ BAB61872 . "Picchu-236-X [synthetic construct]" . . . . . 100.93 740 99.08 99.08 3.48e-64 . . . . 16756 2 10 no DBJ BAC25792 . "unnamed protein product [Mus musculus]" . . . . . 100.93 204 98.17 99.08 3.88e-67 . . . . 16756 2 11 no GB AAB30755 . "c-Crk [Mus sp.]" . . . . . 100.93 304 98.17 99.08 6.71e-66 . . . . 16756 2 12 no GB AAH01718 . "V-crk sarcoma virus CT10 oncogene homolog (avian) [Homo sapiens]" . . . . . 100.93 304 99.08 99.08 3.99e-66 . . . . 16756 2 13 no GB AAH08506 . "V-crk sarcoma virus CT10 oncogene homolog (avian) [Homo sapiens]" . . . . . 100.93 304 99.08 99.08 3.99e-66 . . . . 16756 2 14 no GB AAH09837 . "V-crk sarcoma virus CT10 oncogene homolog (avian) [Homo sapiens]" . . . . . 100.93 204 99.08 99.08 1.68e-67 . . . . 16756 2 15 no GB AAH12216 . "V-crk sarcoma virus CT10 oncogene homolog (avian) [Mus musculus]" . . . . . 100.93 304 98.17 99.08 5.58e-66 . . . . 16756 2 16 no PIR A46243 . "epidermal growth factor-receptor-binding protein GRB-3 - mouse (fragment)" . . . . . 100.93 239 97.25 98.17 4.42e-66 . . . . 16756 2 17 no PIR I58394 . "c-Crk - mouse" . . . . . 100.93 304 98.17 99.08 6.71e-66 . . . . 16756 2 18 no REF NP_001131108 . "adapter molecule crk [Sus scrofa]" . . . . . 100.93 304 99.08 99.08 2.92e-66 . . . . 16756 2 19 no REF NP_001179263 . "adapter molecule crk [Bos taurus]" . . . . . 100.93 304 99.08 99.08 3.99e-66 . . . . 16756 2 20 no REF NP_001264148 . "adapter molecule crk isoform 1 [Mus musculus]" . . . . . 100.93 204 98.17 99.08 3.88e-67 . . . . 16756 2 21 no REF NP_001264150 . "adapter molecule crk isoform 3 [Mus musculus]" . . . . . 64.81 82 100.00 100.00 7.76e-41 . . . . 16756 2 22 no REF NP_005197 . "adapter molecule crk isoform b [Homo sapiens]" . . . . . 100.93 204 99.08 99.08 1.68e-67 . . . . 16756 2 23 no SP P46108 . "RecName: Full=Adapter molecule crk; AltName: Full=Proto-oncogene c-Crk; AltName: Full=p38 [Homo sapiens]" . . . . . 100.93 304 99.08 99.08 3.99e-66 . . . . 16756 2 24 no SP Q63768 . "RecName: Full=Adapter molecule crk; AltName: Full=Proto-oncogene c-Crk; AltName: Full=p38 [Rattus norvegicus]" . . . . . 100.93 304 99.08 99.08 3.74e-66 . . . . 16756 2 25 no SP Q64010 . "RecName: Full=Adapter molecule crk; AltName: Full=Proto-oncogene c-Crk; AltName: Full=p38 [Mus musculus]" . . . . . 100.93 304 98.17 99.08 6.71e-66 . . . . 16756 2 26 no TPG DAA19004 . "TPA: proto-oncogene C-crk-like [Bos taurus]" . . . . . 100.93 304 99.08 99.08 3.99e-66 . . . . 16756 2 stop_ loop_ _Entity_comp_index.ID _Entity_comp_index.Auth_seq_ID _Entity_comp_index.Comp_ID _Entity_comp_index.Comp_label _Entity_comp_index.Entry_ID _Entity_comp_index.Entity_ID 1 . SER . 16756 2 2 . TRP . 16756 2 3 . TYR . 16756 2 4 . TRP . 16756 2 5 . GLY . 16756 2 6 . ARG . 16756 2 7 . LEU . 16756 2 8 . SER . 16756 2 9 . ARG . 16756 2 10 . GLN . 16756 2 11 . GLU . 16756 2 12 . ALA . 16756 2 13 . VAL . 16756 2 14 . ALA . 16756 2 15 . LEU . 16756 2 16 . LEU . 16756 2 17 . GLN . 16756 2 18 . GLY . 16756 2 19 . GLN . 16756 2 20 . ARG . 16756 2 21 . HIS . 16756 2 22 . GLY . 16756 2 23 . VAL . 16756 2 24 . PHE . 16756 2 25 . LEU . 16756 2 26 . VAL . 16756 2 27 . ARG . 16756 2 28 . ASP . 16756 2 29 . SER . 16756 2 30 . SER . 16756 2 31 . THR . 16756 2 32 . SER . 16756 2 33 . PRO . 16756 2 34 . GLY . 16756 2 35 . ASP . 16756 2 36 . TYR . 16756 2 37 . VAL . 16756 2 38 . LEU . 16756 2 39 . SER . 16756 2 40 . VAL . 16756 2 41 . SER . 16756 2 42 . GLU . 16756 2 43 . ASN . 16756 2 44 . SER . 16756 2 45 . ARG . 16756 2 46 . VAL . 16756 2 47 . SER . 16756 2 48 . HIS . 16756 2 49 . TYR . 16756 2 50 . ILE . 16756 2 51 . ILE . 16756 2 52 . ASN . 16756 2 53 . SER . 16756 2 54 . SER . 16756 2 55 . GLY . 16756 2 56 . PRO . 16756 2 57 . ARG . 16756 2 58 . PRO . 16756 2 59 . PRO . 16756 2 60 . VAL . 16756 2 61 . PRO . 16756 2 62 . PRO . 16756 2 63 . SER . 16756 2 64 . PRO . 16756 2 65 . ALA . 16756 2 66 . GLN . 16756 2 67 . PRO . 16756 2 68 . PRO . 16756 2 69 . PRO . 16756 2 70 . GLY . 16756 2 71 . VAL . 16756 2 72 . SER . 16756 2 73 . PRO . 16756 2 74 . SER . 16756 2 75 . ARG . 16756 2 76 . LEU . 16756 2 77 . ARG . 16756 2 78 . ILE . 16756 2 79 . GLY . 16756 2 80 . ASP . 16756 2 81 . GLN . 16756 2 82 . GLU . 16756 2 83 . PHE . 16756 2 84 . ASP . 16756 2 85 . SER . 16756 2 86 . LEU . 16756 2 87 . PRO . 16756 2 88 . ALA . 16756 2 89 . LEU . 16756 2 90 . LEU . 16756 2 91 . GLU . 16756 2 92 . PHE . 16756 2 93 . TYR . 16756 2 94 . LYS . 16756 2 95 . ILE . 16756 2 96 . HIS . 16756 2 97 . TYR . 16756 2 98 . LEU . 16756 2 99 . ASP . 16756 2 100 . THR . 16756 2 101 . THR . 16756 2 102 . THR . 16756 2 103 . LEU . 16756 2 104 . ILE . 16756 2 105 . PRO . 16756 2 106 . VAL . 16756 2 107 . SER . 16756 2 108 . ARG . 16756 2 stop_ loop_ _Entity_poly_seq.Hetero _Entity_poly_seq.Mon_ID _Entity_poly_seq.Num _Entity_poly_seq.Comp_index_ID _Entity_poly_seq.Entry_ID _Entity_poly_seq.Entity_ID . SER 1 1 16756 2 . TRP 2 2 16756 2 . TYR 3 3 16756 2 . TRP 4 4 16756 2 . GLY 5 5 16756 2 . ARG 6 6 16756 2 . LEU 7 7 16756 2 . SER 8 8 16756 2 . ARG 9 9 16756 2 . GLN 10 10 16756 2 . GLU 11 11 16756 2 . ALA 12 12 16756 2 . VAL 13 13 16756 2 . ALA 14 14 16756 2 . LEU 15 15 16756 2 . LEU 16 16 16756 2 . GLN 17 17 16756 2 . GLY 18 18 16756 2 . GLN 19 19 16756 2 . ARG 20 20 16756 2 . HIS 21 21 16756 2 . GLY 22 22 16756 2 . VAL 23 23 16756 2 . PHE 24 24 16756 2 . LEU 25 25 16756 2 . VAL 26 26 16756 2 . ARG 27 27 16756 2 . ASP 28 28 16756 2 . SER 29 29 16756 2 . SER 30 30 16756 2 . THR 31 31 16756 2 . SER 32 32 16756 2 . PRO 33 33 16756 2 . GLY 34 34 16756 2 . ASP 35 35 16756 2 . TYR 36 36 16756 2 . VAL 37 37 16756 2 . LEU 38 38 16756 2 . SER 39 39 16756 2 . VAL 40 40 16756 2 . SER 41 41 16756 2 . GLU 42 42 16756 2 . ASN 43 43 16756 2 . SER 44 44 16756 2 . ARG 45 45 16756 2 . VAL 46 46 16756 2 . SER 47 47 16756 2 . HIS 48 48 16756 2 . TYR 49 49 16756 2 . ILE 50 50 16756 2 . ILE 51 51 16756 2 . ASN 52 52 16756 2 . SER 53 53 16756 2 . SER 54 54 16756 2 . GLY 55 55 16756 2 . PRO 56 56 16756 2 . ARG 57 57 16756 2 . PRO 58 58 16756 2 . PRO 59 59 16756 2 . VAL 60 60 16756 2 . PRO 61 61 16756 2 . PRO 62 62 16756 2 . SER 63 63 16756 2 . PRO 64 64 16756 2 . ALA 65 65 16756 2 . GLN 66 66 16756 2 . PRO 67 67 16756 2 . PRO 68 68 16756 2 . PRO 69 69 16756 2 . GLY 70 70 16756 2 . VAL 71 71 16756 2 . SER 72 72 16756 2 . PRO 73 73 16756 2 . SER 74 74 16756 2 . ARG 75 75 16756 2 . LEU 76 76 16756 2 . ARG 77 77 16756 2 . ILE 78 78 16756 2 . GLY 79 79 16756 2 . ASP 80 80 16756 2 . GLN 81 81 16756 2 . GLU 82 82 16756 2 . PHE 83 83 16756 2 . ASP 84 84 16756 2 . SER 85 85 16756 2 . LEU 86 86 16756 2 . PRO 87 87 16756 2 . ALA 88 88 16756 2 . LEU 89 89 16756 2 . LEU 90 90 16756 2 . GLU 91 91 16756 2 . PHE 92 92 16756 2 . TYR 93 93 16756 2 . LYS 94 94 16756 2 . ILE 95 95 16756 2 . HIS 96 96 16756 2 . TYR 97 97 16756 2 . LEU 98 98 16756 2 . ASP 99 99 16756 2 . THR 100 100 16756 2 . THR 101 101 16756 2 . THR 102 102 16756 2 . LEU 103 103 16756 2 . ILE 104 104 16756 2 . PRO 105 105 16756 2 . VAL 106 106 16756 2 . SER 107 107 16756 2 . ARG 108 108 16756 2 stop_ save_ save_Crk_pY221 _Entity.Sf_category entity _Entity.Sf_framecode Crk_pY221 _Entity.Entry_ID 16756 _Entity.ID 3 _Entity.BMRB_code . _Entity.Name Crk_pY221 _Entity.Type polymer _Entity.Polymer_common_type . _Entity.Polymer_type polypeptide(L) _Entity.Polymer_type_details . _Entity.Polymer_strand_ID . _Entity.Polymer_seq_one_letter_code_can . _Entity.Polymer_seq_one_letter_code EPGPYAQPSVNTK _Entity.Target_identifier . _Entity.Polymer_author_defined_seq . _Entity.Polymer_author_seq_details . _Entity.Ambiguous_conformational_states no _Entity.Ambiguous_chem_comp_sites no _Entity.Nstd_monomer no _Entity.Nstd_chirality no _Entity.Nstd_linkage no _Entity.Nonpolymer_comp_ID . _Entity.Nonpolymer_comp_label . _Entity.Number_of_monomers 13 _Entity.Number_of_nonpolymer_components . _Entity.Paramagnetic no _Entity.Thiol_state 'not present' _Entity.Src_method . _Entity.Parent_entity_ID . _Entity.Fragment . _Entity.Mutation . _Entity.EC_number . _Entity.Calc_isoelectric_point . _Entity.Formula_weight . _Entity.Formula_weight_exptl . _Entity.Formula_weight_exptl_meth . _Entity.Details . _Entity.DB_query_date . _Entity.DB_query_revised_last_date . loop_ _Entity_db_link.Ordinal _Entity_db_link.Author_supplied _Entity_db_link.Database_code _Entity_db_link.Accession_code _Entity_db_link.Entry_mol_code _Entity_db_link.Entry_mol_name _Entity_db_link.Entry_experimental_method _Entity_db_link.Entry_structure_resolution _Entity_db_link.Entry_relation_type _Entity_db_link.Entry_details _Entity_db_link.Chimera_segment_ID _Entity_db_link.Seq_query_to_submitted_percent _Entity_db_link.Seq_subject_length _Entity_db_link.Seq_identity _Entity_db_link.Seq_positive _Entity_db_link.Seq_homology_expectation_val _Entity_db_link.Seq_align_begin _Entity_db_link.Seq_align_end _Entity_db_link.Seq_difference_details _Entity_db_link.Seq_alignment_details _Entity_db_link.Entry_ID _Entity_db_link.Entity_ID . . PDB 1ju5 . . . . . . . . . . . . . . . . 16756 3 stop_ loop_ _Entity_comp_index.ID _Entity_comp_index.Auth_seq_ID _Entity_comp_index.Comp_ID _Entity_comp_index.Comp_label _Entity_comp_index.Entry_ID _Entity_comp_index.Entity_ID 1 . GLU . 16756 3 2 . PRO . 16756 3 3 . GLY . 16756 3 4 . PRO . 16756 3 5 . TYR . 16756 3 6 . ALA . 16756 3 7 . GLN . 16756 3 8 . PRO . 16756 3 9 . SER . 16756 3 10 . VAL . 16756 3 11 . ASN . 16756 3 12 . THR . 16756 3 13 . LYS . 16756 3 stop_ loop_ _Entity_poly_seq.Hetero _Entity_poly_seq.Mon_ID _Entity_poly_seq.Num _Entity_poly_seq.Comp_index_ID _Entity_poly_seq.Entry_ID _Entity_poly_seq.Entity_ID . GLU 1 1 16756 3 . PRO 2 2 16756 3 . GLY 3 3 16756 3 . PRO 4 4 16756 3 . TYR 5 5 16756 3 . ALA 6 6 16756 3 . GLN 7 7 16756 3 . PRO 8 8 16756 3 . SER 9 9 16756 3 . VAL 10 10 16756 3 . ASN 11 11 16756 3 . THR 12 12 16756 3 . LYS 13 13 16756 3 stop_ save_ #################### # Natural source # #################### save_natural_source _Entity_natural_src_list.Sf_category natural_source _Entity_natural_src_list.Sf_framecode natural_source _Entity_natural_src_list.Entry_ID 16756 _Entity_natural_src_list.ID 1 loop_ _Entity_natural_src.ID _Entity_natural_src.Entity_ID _Entity_natural_src.Entity_label _Entity_natural_src.Entity_chimera_segment_ID _Entity_natural_src.NCBI_taxonomy_ID _Entity_natural_src.Type _Entity_natural_src.Common _Entity_natural_src.Organism_name_scientific _Entity_natural_src.Organism_name_common _Entity_natural_src.Organism_acronym _Entity_natural_src.ICTVdb_decimal_code _Entity_natural_src.Superkingdom _Entity_natural_src.Kingdom _Entity_natural_src.Genus _Entity_natural_src.Species _Entity_natural_src.Strain _Entity_natural_src.Variant _Entity_natural_src.Subvariant _Entity_natural_src.Organ _Entity_natural_src.Tissue _Entity_natural_src.Tissue_fraction _Entity_natural_src.Cell_line _Entity_natural_src.Cell_type _Entity_natural_src.ATCC_number _Entity_natural_src.Organelle _Entity_natural_src.Cellular_location _Entity_natural_src.Fragment _Entity_natural_src.Fraction _Entity_natural_src.Secretion _Entity_natural_src.Plasmid _Entity_natural_src.Plasmid_details _Entity_natural_src.Gene_mnemonic _Entity_natural_src.Dev_stage _Entity_natural_src.Details _Entity_natural_src.Citation_ID _Entity_natural_src.Citation_label _Entity_natural_src.Entry_ID _Entity_natural_src.Entity_natural_src_list_ID 1 1 $Abl . 9606 organism . 'Homo sapiens' Human . . Eukaryota Metazoa Homo sapiens . . . . . . . . . . . . . . . . . . . . . 16756 1 2 2 $Crk . 9606 organism . 'Homo sapiens' Human . . Eukaryota Metazoa Homo sapiens . . . . . . . . . . . . . . . . . . . . . 16756 1 stop_ save_ ######################### # Experimental source # ######################### save_experimental_source _Entity_experimental_src_list.Sf_category experimental_source _Entity_experimental_src_list.Sf_framecode experimental_source _Entity_experimental_src_list.Entry_ID 16756 _Entity_experimental_src_list.ID 1 loop_ _Entity_experimental_src.ID _Entity_experimental_src.Entity_ID _Entity_experimental_src.Entity_label _Entity_experimental_src.Entity_chimera_segment_ID _Entity_experimental_src.Production_method _Entity_experimental_src.Host_org_scientific_name _Entity_experimental_src.Host_org_name_common _Entity_experimental_src.Host_org_details _Entity_experimental_src.Host_org_NCBI_taxonomy_ID _Entity_experimental_src.Host_org_genus _Entity_experimental_src.Host_org_species _Entity_experimental_src.Host_org_strain _Entity_experimental_src.Host_org_variant _Entity_experimental_src.Host_org_subvariant _Entity_experimental_src.Host_org_organ _Entity_experimental_src.Host_org_tissue _Entity_experimental_src.Host_org_tissue_fraction _Entity_experimental_src.Host_org_cell_line _Entity_experimental_src.Host_org_cell_type _Entity_experimental_src.Host_org_cellular_location _Entity_experimental_src.Host_org_organelle _Entity_experimental_src.Host_org_gene _Entity_experimental_src.Host_org_culture_collection _Entity_experimental_src.Host_org_ATCC_number _Entity_experimental_src.Vector_type _Entity_experimental_src.PDBview_host_org_vector_name _Entity_experimental_src.PDBview_plasmid_name _Entity_experimental_src.Vector_name _Entity_experimental_src.Vector_details _Entity_experimental_src.Vendor_name _Entity_experimental_src.Host_org_dev_stage _Entity_experimental_src.Details _Entity_experimental_src.Citation_ID _Entity_experimental_src.Citation_label _Entity_experimental_src.Entry_ID _Entity_experimental_src.Entity_experimental_src_list_ID 1 1 $Abl . 'recombinant technology' 'Escherichia coli' . . . Escherichia coli . . . . . . . . . . . . . . . . pET11d . . . . . . 16756 1 2 2 $Crk . 'recombinant technology' 'Escherichia coli' . . . Escherichia coli BL21 DE3 . . . . . . . . . . . . . . na . . . . . . 16756 1 stop_ save_ ##################################### # Sample contents and methodology # ##################################### ######################## # Sample description # ######################## save_sample_1 _Sample.Sf_category sample _Sample.Sf_framecode sample_1 _Sample.Entry_ID 16756 _Sample.ID 1 _Sample.Type solution _Sample.Sub_type . _Sample.Details . _Sample.Aggregate_sample_number . _Sample.Solvent_system '1% H2O/99% D2O' _Sample.Preparation_date . _Sample.Preparation_expiration_date . _Sample.Polycrystallization_protocol . _Sample.Single_crystal_protocol . _Sample.Crystal_grow_apparatus . _Sample.Crystal_grow_atmosphere . _Sample.Crystal_grow_details . _Sample.Crystal_grow_method . _Sample.Crystal_grow_method_cit_ID . _Sample.Crystal_grow_pH . _Sample.Crystal_grow_pH_range . _Sample.Crystal_grow_pressure . _Sample.Crystal_grow_pressure_esd . _Sample.Crystal_grow_seeding . _Sample.Crystal_grow_seeding_cit_ID . _Sample.Crystal_grow_temp . _Sample.Crystal_grow_temp_details . _Sample.Crystal_grow_temp_esd . _Sample.Crystal_grow_time . _Sample.Oriented_sample_prep_protocol . _Sample.Lyophilization_cryo_protectant . _Sample.Storage_protocol . loop_ _Sample_component.ID _Sample_component.Mol_common_name _Sample_component.Isotopic_labeling _Sample_component.Assembly_ID _Sample_component.Assembly_label _Sample_component.Entity_ID _Sample_component.Entity_label _Sample_component.Product_ID _Sample_component.Type _Sample_component.Concentration_val _Sample_component.Concentration_val_min _Sample_component.Concentration_val_max _Sample_component.Concentration_val_units _Sample_component.Concentration_val_err _Sample_component.Vendor _Sample_component.Vendor_product_name _Sample_component.Vendor_product_code _Sample_component.Entry_ID _Sample_component.Sample_ID 1 Abl [U-15N] . . 1 $Abl . . 0.47 . . mM . . . . 16756 1 2 'sodium phosphate' 'natural abundance' . . . . . . 50 . . mM . . . . 16756 1 3 'sodium azide' 'natural abundance' . . . . . . 0.02 . . % . . . . 16756 1 4 H2O 'natural abundance' . . . . . . 1 . . % . . . . 16756 1 5 D2O 'natural abundance' . . . . . . 99 . . % . . . . 16756 1 stop_ save_ save_sample_2 _Sample.Sf_category sample _Sample.Sf_framecode sample_2 _Sample.Entry_ID 16756 _Sample.ID 2 _Sample.Type solution _Sample.Sub_type . _Sample.Details . _Sample.Aggregate_sample_number . _Sample.Solvent_system '1% H2O/99% D2O' _Sample.Preparation_date . _Sample.Preparation_expiration_date . _Sample.Polycrystallization_protocol . _Sample.Single_crystal_protocol . _Sample.Crystal_grow_apparatus . _Sample.Crystal_grow_atmosphere . _Sample.Crystal_grow_details . _Sample.Crystal_grow_method . _Sample.Crystal_grow_method_cit_ID . _Sample.Crystal_grow_pH . _Sample.Crystal_grow_pH_range . _Sample.Crystal_grow_pressure . _Sample.Crystal_grow_pressure_esd . _Sample.Crystal_grow_seeding . _Sample.Crystal_grow_seeding_cit_ID . _Sample.Crystal_grow_temp . _Sample.Crystal_grow_temp_details . _Sample.Crystal_grow_temp_esd . _Sample.Crystal_grow_time . _Sample.Oriented_sample_prep_protocol . _Sample.Lyophilization_cryo_protectant . _Sample.Storage_protocol . loop_ _Sample_component.ID _Sample_component.Mol_common_name _Sample_component.Isotopic_labeling _Sample_component.Assembly_ID _Sample_component.Assembly_label _Sample_component.Entity_ID _Sample_component.Entity_label _Sample_component.Product_ID _Sample_component.Type _Sample_component.Concentration_val _Sample_component.Concentration_val_min _Sample_component.Concentration_val_max _Sample_component.Concentration_val_units _Sample_component.Concentration_val_err _Sample_component.Vendor _Sample_component.Vendor_product_name _Sample_component.Vendor_product_code _Sample_component.Entry_ID _Sample_component.Sample_ID 1 Abl [U-15N] . . 1 $Abl . . 0.47 . . mM . . . . 16756 2 2 Crk 'natural abundance' . . 2 $Crk . . 0.1175 . . mM . . . . 16756 2 3 'Crk pY221' 'natural abundance' . . 3 $Crk_pY221 . . 0.1175 . . mM . . . . 16756 2 4 'sodium phosphate' 'natural abundance' . . . . . . 50 . . mM . . . . 16756 2 5 'sodium azide' 'natural abundance' . . . . . . 0.02 . . % . . . . 16756 2 6 H2O 'natural abundance' . . . . . . 1 . . % . . . . 16756 2 7 D2O 'natural abundance' . . . . . . 99 . . % . . . . 16756 2 stop_ save_ save_sample_3 _Sample.Sf_category sample _Sample.Sf_framecode sample_3 _Sample.Entry_ID 16756 _Sample.ID 3 _Sample.Type solution _Sample.Sub_type . _Sample.Details . _Sample.Aggregate_sample_number . _Sample.Solvent_system '1% H2O/99% D2O' _Sample.Preparation_date . _Sample.Preparation_expiration_date . _Sample.Polycrystallization_protocol . _Sample.Single_crystal_protocol . _Sample.Crystal_grow_apparatus . _Sample.Crystal_grow_atmosphere . _Sample.Crystal_grow_details . _Sample.Crystal_grow_method . _Sample.Crystal_grow_method_cit_ID . _Sample.Crystal_grow_pH . _Sample.Crystal_grow_pH_range . _Sample.Crystal_grow_pressure . _Sample.Crystal_grow_pressure_esd . _Sample.Crystal_grow_seeding . _Sample.Crystal_grow_seeding_cit_ID . _Sample.Crystal_grow_temp . _Sample.Crystal_grow_temp_details . _Sample.Crystal_grow_temp_esd . _Sample.Crystal_grow_time . _Sample.Oriented_sample_prep_protocol . _Sample.Lyophilization_cryo_protectant . _Sample.Storage_protocol . loop_ _Sample_component.ID _Sample_component.Mol_common_name _Sample_component.Isotopic_labeling _Sample_component.Assembly_ID _Sample_component.Assembly_label _Sample_component.Entity_ID _Sample_component.Entity_label _Sample_component.Product_ID _Sample_component.Type _Sample_component.Concentration_val _Sample_component.Concentration_val_min _Sample_component.Concentration_val_max _Sample_component.Concentration_val_units _Sample_component.Concentration_val_err _Sample_component.Vendor _Sample_component.Vendor_product_name _Sample_component.Vendor_product_code _Sample_component.Entry_ID _Sample_component.Sample_ID 1 Abl [U-15N] . . 1 $Abl . . 0.47 . . mM . . . . 16756 3 2 Crk 'natural abundance' . . 2 $Crk . . 0.235 . . mM . . . . 16756 3 3 'Crk pY221' 'natural abundance' . . 3 $Crk_pY221 . . 0.235 . . mM . . . . 16756 3 4 'sodium phosphate' 'natural abundance' . . . . . . 50 . . mM . . . . 16756 3 5 'sodium azide' 'natural abundance' . . . . . . 0.02 . . % . . . . 16756 3 6 H2O 'natural abundance' . . . . . . 1 . . % . . . . 16756 3 7 D2O 'natural abundance' . . . . . . 99 . . % . . . . 16756 3 stop_ save_ save_sample_4 _Sample.Sf_category sample _Sample.Sf_framecode sample_4 _Sample.Entry_ID 16756 _Sample.ID 4 _Sample.Type solution _Sample.Sub_type . _Sample.Details . _Sample.Aggregate_sample_number . _Sample.Solvent_system '1% H2O/99% D2O' _Sample.Preparation_date . _Sample.Preparation_expiration_date . _Sample.Polycrystallization_protocol . _Sample.Single_crystal_protocol . _Sample.Crystal_grow_apparatus . _Sample.Crystal_grow_atmosphere . _Sample.Crystal_grow_details . _Sample.Crystal_grow_method . _Sample.Crystal_grow_method_cit_ID . _Sample.Crystal_grow_pH . _Sample.Crystal_grow_pH_range . _Sample.Crystal_grow_pressure . _Sample.Crystal_grow_pressure_esd . _Sample.Crystal_grow_seeding . _Sample.Crystal_grow_seeding_cit_ID . _Sample.Crystal_grow_temp . _Sample.Crystal_grow_temp_details . _Sample.Crystal_grow_temp_esd . _Sample.Crystal_grow_time . _Sample.Oriented_sample_prep_protocol . _Sample.Lyophilization_cryo_protectant . _Sample.Storage_protocol . loop_ _Sample_component.ID _Sample_component.Mol_common_name _Sample_component.Isotopic_labeling _Sample_component.Assembly_ID _Sample_component.Assembly_label _Sample_component.Entity_ID _Sample_component.Entity_label _Sample_component.Product_ID _Sample_component.Type _Sample_component.Concentration_val _Sample_component.Concentration_val_min _Sample_component.Concentration_val_max _Sample_component.Concentration_val_units _Sample_component.Concentration_val_err _Sample_component.Vendor _Sample_component.Vendor_product_name _Sample_component.Vendor_product_code _Sample_component.Entry_ID _Sample_component.Sample_ID 1 Abl [U-15N] . . 1 $Abl . . 0.47 . . mM . . . . 16756 4 2 Crk 'natural abundance' . . 2 $Crk . . 0.3525 . . mM . . . . 16756 4 3 'Crk pY221' 'natural abundance' . . 3 $Crk_pY221 . . 0.3525 . . mM . . . . 16756 4 4 'sodium phosphate' 'natural abundance' . . . . . . 50 . . mM . . . . 16756 4 5 'sodium azide' 'natural abundance' . . . . . . 0.02 . . % . . . . 16756 4 6 H2O 'natural abundance' . . . . . . 1 . . % . . . . 16756 4 7 D2O 'natural abundance' . . . . . . 99 . . % . . . . 16756 4 stop_ save_ save_sample_5 _Sample.Sf_category sample _Sample.Sf_framecode sample_5 _Sample.Entry_ID 16756 _Sample.ID 5 _Sample.Type solution _Sample.Sub_type . _Sample.Details . _Sample.Aggregate_sample_number . _Sample.Solvent_system '1% H2O/99% D2O' _Sample.Preparation_date . _Sample.Preparation_expiration_date . _Sample.Polycrystallization_protocol . _Sample.Single_crystal_protocol . _Sample.Crystal_grow_apparatus . _Sample.Crystal_grow_atmosphere . _Sample.Crystal_grow_details . _Sample.Crystal_grow_method . _Sample.Crystal_grow_method_cit_ID . _Sample.Crystal_grow_pH . _Sample.Crystal_grow_pH_range . _Sample.Crystal_grow_pressure . _Sample.Crystal_grow_pressure_esd . _Sample.Crystal_grow_seeding . _Sample.Crystal_grow_seeding_cit_ID . _Sample.Crystal_grow_temp . _Sample.Crystal_grow_temp_details . _Sample.Crystal_grow_temp_esd . _Sample.Crystal_grow_time . _Sample.Oriented_sample_prep_protocol . _Sample.Lyophilization_cryo_protectant . _Sample.Storage_protocol . loop_ _Sample_component.ID _Sample_component.Mol_common_name _Sample_component.Isotopic_labeling _Sample_component.Assembly_ID _Sample_component.Assembly_label _Sample_component.Entity_ID _Sample_component.Entity_label _Sample_component.Product_ID _Sample_component.Type _Sample_component.Concentration_val _Sample_component.Concentration_val_min _Sample_component.Concentration_val_max _Sample_component.Concentration_val_units _Sample_component.Concentration_val_err _Sample_component.Vendor _Sample_component.Vendor_product_name _Sample_component.Vendor_product_code _Sample_component.Entry_ID _Sample_component.Sample_ID 1 Abl [U-15N] . . 1 $Abl . . 0.47 . . mM . . . . 16756 5 2 Crk 'natural abundance' . . 2 $Crk . . 0.47 . . mM . . . . 16756 5 3 'Crk pY221' 'natural abundance' . . 3 $Crk_pY221 . . 0.47 . . mM . . . . 16756 5 4 'sodium phosphate' 'natural abundance' . . . . . . 50 . . mM . . . . 16756 5 5 'sodium azide' 'natural abundance' . . . . . . 0.02 . . % . . . . 16756 5 6 H2O 'natural abundance' . . . . . . 1 . . % . . . . 16756 5 7 D2O 'natural abundance' . . . . . . 99 . . % . . . . 16756 5 stop_ save_ save_sample_6 _Sample.Sf_category sample _Sample.Sf_framecode sample_6 _Sample.Entry_ID 16756 _Sample.ID 6 _Sample.Type solution _Sample.Sub_type . _Sample.Details . _Sample.Aggregate_sample_number . _Sample.Solvent_system '1% H2O/99% D2O' _Sample.Preparation_date . _Sample.Preparation_expiration_date . _Sample.Polycrystallization_protocol . _Sample.Single_crystal_protocol . _Sample.Crystal_grow_apparatus . _Sample.Crystal_grow_atmosphere . _Sample.Crystal_grow_details . _Sample.Crystal_grow_method . _Sample.Crystal_grow_method_cit_ID . _Sample.Crystal_grow_pH . _Sample.Crystal_grow_pH_range . _Sample.Crystal_grow_pressure . _Sample.Crystal_grow_pressure_esd . _Sample.Crystal_grow_seeding . _Sample.Crystal_grow_seeding_cit_ID . _Sample.Crystal_grow_temp . _Sample.Crystal_grow_temp_details . _Sample.Crystal_grow_temp_esd . _Sample.Crystal_grow_time . _Sample.Oriented_sample_prep_protocol . _Sample.Lyophilization_cryo_protectant . _Sample.Storage_protocol . loop_ _Sample_component.ID _Sample_component.Mol_common_name _Sample_component.Isotopic_labeling _Sample_component.Assembly_ID _Sample_component.Assembly_label _Sample_component.Entity_ID _Sample_component.Entity_label _Sample_component.Product_ID _Sample_component.Type _Sample_component.Concentration_val _Sample_component.Concentration_val_min _Sample_component.Concentration_val_max _Sample_component.Concentration_val_units _Sample_component.Concentration_val_err _Sample_component.Vendor _Sample_component.Vendor_product_name _Sample_component.Vendor_product_code _Sample_component.Entry_ID _Sample_component.Sample_ID 1 Abl [U-15N] . . 1 $Abl . . 0.47 . . mM . . . . 16756 6 2 Crk 'natural abundance' . . 2 $Crk . . 0.705 . . mM . . . . 16756 6 3 'Crk pY221' 'natural abundance' . . 3 $Crk_pY221 . . 0.705 . . mM . . . . 16756 6 4 'sodium phosphate' 'natural abundance' . . . . . . 50 . . mM . . . . 16756 6 5 'sodium azide' 'natural abundance' . . . . . . 0.02 . . % . . . . 16756 6 6 H2O 'natural abundance' . . . . . . 1 . . % . . . . 16756 6 7 D2O 'natural abundance' . . . . . . 99 . . % . . . . 16756 6 stop_ save_ ####################### # Sample conditions # ####################### save_sample_conditions_1 _Sample_condition_list.Sf_category sample_conditions _Sample_condition_list.Sf_framecode sample_conditions_1 _Sample_condition_list.Entry_ID 16756 _Sample_condition_list.ID 1 _Sample_condition_list.Details . loop_ _Sample_condition_variable.Type _Sample_condition_variable.Val _Sample_condition_variable.Val_err _Sample_condition_variable.Val_units _Sample_condition_variable.Entry_ID _Sample_condition_variable.Sample_condition_list_ID pH 6.8 . pH 16756 1 pressure 1 . atm 16756 1 temperature 303 . K 16756 1 stop_ save_ ############################ # Computer software used # ############################ save_PIPP _Software.Sf_category software _Software.Sf_framecode PIPP _Software.Entry_ID 16756 _Software.ID 1 _Software.Name PIPP _Software.Version . _Software.Details . loop_ _Vendor.Name _Vendor.Address _Vendor.Electronic_address _Vendor.Entry_ID _Vendor.Software_ID Garrett . . 16756 1 stop_ loop_ _Task.Task _Task.Entry_ID _Task.Software_ID 'data analysis' 16756 1 stop_ save_ save_NMRPipe _Software.Sf_category software _Software.Sf_framecode NMRPipe _Software.Entry_ID 16756 _Software.ID 2 _Software.Name NMRPipe _Software.Version . _Software.Details . loop_ _Vendor.Name _Vendor.Address _Vendor.Electronic_address _Vendor.Entry_ID _Vendor.Software_ID 'Delaglio, Grzesiek, Vuister, Zhu, Pfeifer and Bax' . . 16756 2 stop_ loop_ _Task.Task _Task.Entry_ID _Task.Software_ID processing 16756 2 stop_ save_ save_ARIA _Software.Sf_category software _Software.Sf_framecode ARIA _Software.Entry_ID 16756 _Software.ID 3 _Software.Name ARIA _Software.Version . _Software.Details . loop_ _Vendor.Name _Vendor.Address _Vendor.Electronic_address _Vendor.Entry_ID _Vendor.Software_ID 'Linge, O'Donoghue and Nilges' . . 16756 3 stop_ loop_ _Task.Task _Task.Entry_ID _Task.Software_ID 'structure solution' 16756 3 stop_ save_ save_CNS _Software.Sf_category software _Software.Sf_framecode CNS _Software.Entry_ID 16756 _Software.ID 4 _Software.Name CNS _Software.Version 1.0 _Software.Details . loop_ _Vendor.Name _Vendor.Address _Vendor.Electronic_address _Vendor.Entry_ID _Vendor.Software_ID 'Brunger, Adams, Clore, Gros, Nilges and Read' . . 16756 4 stop_ loop_ _Task.Task _Task.Entry_ID _Task.Software_ID 'structure solution' 16756 4 stop_ save_ save_TALOS _Software.Sf_category software _Software.Sf_framecode TALOS _Software.Entry_ID 16756 _Software.ID 5 _Software.Name TALOS _Software.Version . _Software.Details . loop_ _Vendor.Name _Vendor.Address _Vendor.Electronic_address _Vendor.Entry_ID _Vendor.Software_ID 'Cornilescu, Delaglio and Bax' . . 16756 5 stop_ loop_ _Task.Task _Task.Entry_ID _Task.Software_ID 'structure solution' 16756 5 stop_ save_ save_Procheck _Software.Sf_category software _Software.Sf_framecode Procheck _Software.Entry_ID 16756 _Software.ID 6 _Software.Name Procheck _Software.Version . _Software.Details . loop_ _Vendor.Name _Vendor.Address _Vendor.Electronic_address _Vendor.Entry_ID _Vendor.Software_ID 'Laskowski, MacArthur, Smith, Jones, Hutchinson, Morris, Moss and Tho' . . 16756 6 stop_ loop_ _Task.Task _Task.Entry_ID _Task.Software_ID 'structure assessment' 16756 6 stop_ save_ ######################### # Experimental detail # ######################### ################################## # NMR Spectrometer definitions # ################################## save_spectrometer_1 _NMR_spectrometer.Sf_category NMR_spectrometer _NMR_spectrometer.Sf_framecode spectrometer_1 _NMR_spectrometer.Entry_ID 16756 _NMR_spectrometer.ID 1 _NMR_spectrometer.Details . _NMR_spectrometer.Manufacturer Varian _NMR_spectrometer.Model 'Unity Inova' _NMR_spectrometer.Serial_number . _NMR_spectrometer.Field_strength 500 save_ save_spectrometer_2 _NMR_spectrometer.Sf_category NMR_spectrometer _NMR_spectrometer.Sf_framecode spectrometer_2 _NMR_spectrometer.Entry_ID 16756 _NMR_spectrometer.ID 2 _NMR_spectrometer.Details . _NMR_spectrometer.Manufacturer Varian _NMR_spectrometer.Model 'Unity Inova' _NMR_spectrometer.Serial_number . _NMR_spectrometer.Field_strength 600 save_ save_spectrometer_3 _NMR_spectrometer.Sf_category NMR_spectrometer _NMR_spectrometer.Sf_framecode spectrometer_3 _NMR_spectrometer.Entry_ID 16756 _NMR_spectrometer.ID 3 _NMR_spectrometer.Details . _NMR_spectrometer.Manufacturer Varian _NMR_spectrometer.Model 'Unity Inova' _NMR_spectrometer.Serial_number . _NMR_spectrometer.Field_strength 800 save_ save_NMR_spectrometer_list _NMR_spectrometer_list.Sf_category NMR_spectrometer_list _NMR_spectrometer_list.Sf_framecode NMR_spectrometer_list _NMR_spectrometer_list.Entry_ID 16756 _NMR_spectrometer_list.ID 1 loop_ _NMR_spectrometer_view.ID _NMR_spectrometer_view.Name _NMR_spectrometer_view.Manufacturer _NMR_spectrometer_view.Model _NMR_spectrometer_view.Serial_number _NMR_spectrometer_view.Field_strength _NMR_spectrometer_view.Details _NMR_spectrometer_view.Citation_ID _NMR_spectrometer_view.Citation_label _NMR_spectrometer_view.Entry_ID _NMR_spectrometer_view.NMR_spectrometer_list_ID 1 spectrometer_1 Varian 'Unity Inova' . 500 . . . 16756 1 2 spectrometer_2 Varian 'Unity Inova' . 600 . . . 16756 1 3 spectrometer_3 Varian 'Unity Inova' . 800 . . . 16756 1 stop_ save_ ############################# # NMR applied experiments # ############################# save_experiment_list _Experiment_list.Sf_category experiment_list _Experiment_list.Sf_framecode experiment_list _Experiment_list.Entry_ID 16756 _Experiment_list.ID 1 _Experiment_list.Details . loop_ _Experiment.ID _Experiment.Name _Experiment.Raw_data_flag _Experiment.NMR_spec_expt_ID _Experiment.NMR_spec_expt_label _Experiment.MS_expt_ID _Experiment.MS_expt_label _Experiment.SAXS_expt_ID _Experiment.SAXS_expt_label _Experiment.FRET_expt_ID _Experiment.FRET_expt_label _Experiment.EMR_expt_ID _Experiment.EMR_expt_label _Experiment.Sample_ID _Experiment.Sample_label _Experiment.Sample_state _Experiment.Sample_volume _Experiment.Sample_volume_units _Experiment.Sample_condition_list_ID _Experiment.Sample_condition_list_label _Experiment.Sample_spinning_rate _Experiment.Sample_angle _Experiment.NMR_tube_type _Experiment.NMR_spectrometer_ID _Experiment.NMR_spectrometer_label _Experiment.NMR_spectrometer_probe_ID _Experiment.NMR_spectrometer_probe_label _Experiment.NMR_spectral_processing_ID _Experiment.NMR_spectral_processing_label _Experiment.Mass_spectrometer_ID _Experiment.Mass_spectrometer_label _Experiment.Xray_instrument_ID _Experiment.Xray_instrument_label _Experiment.Fluorescence_instrument_ID _Experiment.Fluorescence_instrument_label _Experiment.EMR_instrument_ID _Experiment.EMR_instrument_label _Experiment.Chromatographic_system_ID _Experiment.Chromatographic_system_label _Experiment.Chromatographic_column_ID _Experiment.Chromatographic_column_label _Experiment.Entry_ID _Experiment.Experiment_list_ID 1 '2D 1H-15N HSQC' no . . . . . . . . . . 1 $sample_1 isotropic . . 1 $sample_conditions_1 . . . . . . . . . . . . . . . . . . . . . 16756 1 2 '2D 1H-15N HSQC' no . . . . . . . . . . 2 $sample_2 isotropic . . 1 $sample_conditions_1 . . . . . . . . . . . . . . . . . . . . . 16756 1 3 '2D 1H-15N HSQC' no . . . . . . . . . . 3 $sample_3 isotropic . . 1 $sample_conditions_1 . . . . . . . . . . . . . . . . . . . . . 16756 1 4 '2D 1H-15N HSQC' no . . . . . . . . . . 4 $sample_4 isotropic . . 1 $sample_conditions_1 . . . . . . . . . . . . . . . . . . . . . 16756 1 5 '2D 1H-15N HSQC' no . . . . . . . . . . 5 $sample_5 isotropic . . 1 $sample_conditions_1 . . . . . . . . . . . . . . . . . . . . . 16756 1 6 '2D 1H-15N HSQC' no . . . . . . . . . . 6 $sample_6 isotropic . . 1 $sample_conditions_1 . . . . . . . . . . . . . . . . . . . . . 16756 1 7 NOESY-HSQC no . . . . . . . . . . 1 $sample_1 isotropic . . 1 $sample_conditions_1 . . . . . . . . . . . . . . . . . . . . . 16756 1 8 NOESY-HSQC no . . . . . . . . . . 2 $sample_2 isotropic . . 1 $sample_conditions_1 . . . . . . . . . . . . . . . . . . . . . 16756 1 9 NOESY-HSQC no . . . . . . . . . . 3 $sample_3 isotropic . . 1 $sample_conditions_1 . . . . . . . . . . . . . . . . . . . . . 16756 1 10 NOESY-HSQC no . . . . . . . . . . 4 $sample_4 isotropic . . 1 $sample_conditions_1 . . . . . . . . . . . . . . . . . . . . . 16756 1 11 NOESY-HSQC no . . . . . . . . . . 5 $sample_5 isotropic . . 1 $sample_conditions_1 . . . . . . . . . . . . . . . . . . . . . 16756 1 12 NOESY-HSQC no . . . . . . . . . . 6 $sample_6 isotropic . . 1 $sample_conditions_1 . . . . . . . . . . . . . . . . . . . . . 16756 1 13 TOCSY-HSQC no . . . . . . . . . . 1 $sample_1 isotropic . . 1 $sample_conditions_1 . . . . . . . . . . . . . . . . . . . . . 16756 1 14 TOCSY-HSQC no . . . . . . . . . . 2 $sample_2 isotropic . . 1 $sample_conditions_1 . . . . . . . . . . . . . . . . . . . . . 16756 1 15 TOCSY-HSQC no . . . . . . . . . . 3 $sample_3 isotropic . . 1 $sample_conditions_1 . . . . . . . . . . . . . . . . . . . . . 16756 1 16 TOCSY-HSQC no . . . . . . . . . . 4 $sample_4 isotropic . . 1 $sample_conditions_1 . . . . . . . . . . . . . . . . . . . . . 16756 1 17 TOCSY-HSQC no . . . . . . . . . . 5 $sample_5 isotropic . . 1 $sample_conditions_1 . . . . . . . . . . . . . . . . . . . . . 16756 1 18 TOCSY-HSQC no . . . . . . . . . . 6 $sample_6 isotropic . . 1 $sample_conditions_1 . . . . . . . . . . . . . . . . . . . . . 16756 1 stop_ save_ save_binding_data _Binding_value_list.Sf_category binding_data _Binding_value_list.Sf_framecode binding_data _Binding_value_list.Entry_ID 16756 _Binding_value_list.ID 1 _Binding_value_list.Sample_condition_list_ID 1 _Binding_value_list.Sample_condition_list_label $sample_conditions_1 _Binding_value_list.Details . _Binding_value_list.Text_data_format . _Binding_value_list.Text_data . loop_ _Binding_experiment.Experiment_ID _Binding_experiment.Experiment_name _Binding_experiment.Sample_ID _Binding_experiment.Sample_label _Binding_experiment.Sample_state _Binding_experiment.Entry_ID _Binding_experiment.Binding_value_list_ID 1 '2D 1H-15N HSQC' 1 $sample_1 isotropic 16756 1 2 '2D 1H-15N HSQC' 2 $sample_2 isotropic 16756 1 3 '2D 1H-15N HSQC' 3 $sample_3 isotropic 16756 1 4 '2D 1H-15N HSQC' 4 $sample_4 isotropic 16756 1 5 '2D 1H-15N HSQC' 5 $sample_5 isotropic 16756 1 6 '2D 1H-15N HSQC' 6 $sample_6 isotropic 16756 1 7 NOESY-HSQC 1 $sample_1 isotropic 16756 1 8 NOESY-HSQC 2 $sample_2 isotropic 16756 1 9 NOESY-HSQC 3 $sample_3 isotropic 16756 1 10 NOESY-HSQC 4 $sample_4 isotropic 16756 1 11 NOESY-HSQC 5 $sample_5 isotropic 16756 1 12 NOESY-HSQC 6 $sample_6 isotropic 16756 1 13 TOCSY-HSQC 1 $sample_1 isotropic 16756 1 14 TOCSY-HSQC 2 $sample_2 isotropic 16756 1 15 TOCSY-HSQC 3 $sample_3 isotropic 16756 1 16 TOCSY-HSQC 4 $sample_4 isotropic 16756 1 17 TOCSY-HSQC 5 $sample_5 isotropic 16756 1 18 TOCSY-HSQC 6 $sample_6 isotropic 16756 1 stop_ loop_ _Binding_software.Software_ID _Binding_software.Software_label _Binding_software.Method_ID _Binding_software.Method_label _Binding_software.Entry_ID _Binding_software.Binding_value_list_ID 1 $PIPP . . 16756 1 2 $NMRPipe . . 16756 1 3 $ARIA . . 16756 1 4 $CNS . . 16756 1 5 $TALOS . . 16756 1 6 $Procheck . . 16756 1 stop_ loop_ _Binding_result.ID _Binding_result.Experiment_ID _Binding_result.Assembly_ID _Binding_result.Atm_obs_assembly_atom_ID _Binding_result.Atm_obs_entity_assembly_ID _Binding_result.Atm_obs_entity_ID _Binding_result.Atm_obs_comp_index_ID _Binding_result.Atm_obs_seq_ID _Binding_result.Atm_obs_comp_ID _Binding_result.Atm_obs_atom_ID _Binding_result.Atm_obs_atom_type _Binding_result.Atm_obs_atom_isotope_number _Binding_result.Resonance_ID _Binding_result.Atm_obs_auth_entity_assembly_ID _Binding_result.Atm_obs_auth_seq_ID _Binding_result.Atm_obs_auth_comp_ID _Binding_result.Atm_obs_auth_atom_ID _Binding_result.Expt_observed_param _Binding_result.Val_type _Binding_result.Val _Binding_result.Val_err _Binding_result.Val_units _Binding_result.Entry_ID _Binding_result.Binding_value_list_ID 1 1 1 . 1 1 . . . . . . . . . . . 'chemical shifts' Kd 30 11 uM 16756 1 2 2 1 . 1 1 . . . . . . . . . . . 'chemical shifts' Kd 30 11 uM 16756 1 3 3 1 . 1 1 . . . . . . . . . . . 'chemical shifts' Kd 30 11 uM 16756 1 4 4 1 . 1 1 . . . . . . . . . . . 'chemical shifts' Kd 30 11 uM 16756 1 5 5 1 . 1 1 . . . . . . . . . . . 'chemical shifts' Kd 30 11 uM 16756 1 6 6 1 . 1 1 . . . . . . . . . . . 'chemical shifts' Kd 30 11 uM 16756 1 stop_ loop_ _Binding_partners.Binding_result_ID _Binding_partners.Assembly_ID _Binding_partners.Entity_assembly_ID _Binding_partners.Entity_assembly_name _Binding_partners.Entity_ID _Binding_partners.Entity_label _Binding_partners.Entry_ID _Binding_partners.Binding_value_list_ID 1 1 1 Ab1 1 $Abl 16756 1 1 1 2 Crk 2 $Crk 16756 1 1 1 3 'Crk pY221' 3 $Crk_pY221 16756 1 2 1 1 Ab1 1 $Abl 16756 1 2 1 2 Crk 2 $Crk 16756 1 2 1 3 'Crk pY221' 3 $Crk_pY221 16756 1 3 1 1 Ab1 1 $Abl 16756 1 3 1 2 Crk 2 $Crk 16756 1 3 1 3 'Crk pY221' 3 $Crk_pY221 16756 1 4 1 1 Ab1 1 $Abl 16756 1 4 1 2 Crk 2 $Crk 16756 1 4 1 3 'Crk pY221' 3 $Crk_pY221 16756 1 5 1 1 Ab1 1 $Abl 16756 1 5 1 2 Crk 2 $Crk 16756 1 5 1 3 'Crk pY221' 3 $Crk_pY221 16756 1 6 1 1 Ab1 1 $Abl 16756 1 6 1 2 Crk 2 $Crk 16756 1 6 1 3 'Crk pY221' 3 $Crk_pY221 16756 1 stop_ save_