data_2476 ####################### # Entry information # ####################### save_entry_information _Entry.Sf_category entry_information _Entry.Sf_framecode entry_information _Entry.ID 2476 _Entry.Title ; A Proton NMR and Nuclear Overhauser Effect (NOE) Study of Human Plasma Prealbumin, Including the Development and Application to Spectral Assignment of a Combined Ring Current Shift and NOE Prediction Program ; _Entry.Type macromolecule _Entry.Version_type update _Entry.Submission_date 1995-07-31 _Entry.Accession_date 1996-04-13 _Entry.Last_release_date . _Entry.Original_release_date . _Entry.Origination BMRB _Entry.NMR_STAR_version 3.1.1.61 _Entry.Original_NMR_STAR_version 2.1 _Entry.Experimental_method NMR _Entry.Experimental_method_subtype . _Entry.Details . _Entry.BMRB_internal_directory_name . loop_ _Entry_author.Ordinal _Entry_author.Given_name _Entry_author.Family_name _Entry_author.First_initial _Entry_author.Middle_initials _Entry_author.Family_title _Entry_author.Entry_ID 1 David Reid . G. . 2476 2 Martin Saunders . . . 2476 stop_ loop_ _Data_set.Type _Data_set.Count _Data_set.Entry_ID assigned_chemical_shifts 1 2476 stop_ loop_ _Datum.Type _Datum.Count _Datum.Entry_ID '1H chemical shifts' 50 2476 stop_ loop_ _Release.Release_number _Release.Format_type _Release.Format_version _Release.Date _Release.Submission_date _Release.Type _Release.Author _Release.Detail _Release.Entry_ID 5 . . 2010-06-17 . revision BMRB 'Complete natural source information' 2476 4 . . 1999-06-14 . revision BMRB 'Converted to BMRB NMR-STAR V 2.1 format' 2476 3 . . 1996-04-13 . revision BMRB 'Link to the Protein Data Bank added' 2476 2 . . 1996-03-25 . reformat BMRB 'Converted to the BMRB 1996-03-01 STAR flat-file format' 2476 1 . . 1995-07-31 . original BMRB 'Last release in original BMRB flat-file format' 2476 stop_ save_ ############### # Citations # ############### save_entry_citation _Citation.Sf_category citations _Citation.Sf_framecode entry_citation _Citation.Entry_ID 2476 _Citation.ID 1 _Citation.Class 'entry citation' _Citation.CAS_abstract_code . _Citation.MEDLINE_UI_code . _Citation.DOI . _Citation.PubMed_ID . _Citation.Full_citation ; Reid, David G., Saunders, Martin, "A Proton NMR and Nuclear Overhauser Effect (NOE) Study of Human Plasma Prealbumin, Including the Development and Application to Spectral Assignment of a Combined Ring Current Shift and NOE Prediction Program," J. Biol. Chem. 264 (4), 2003-2012 (1989). ; _Citation.Title ; A Proton NMR and Nuclear Overhauser Effect (NOE) Study of Human Plasma Prealbumin, Including the Development and Application to Spectral Assignment of a Combined Ring Current Shift and NOE Prediction Program ; _Citation.Status published _Citation.Type journal _Citation.Journal_abbrev 'J. Biol. Chem.' _Citation.Journal_name_full . _Citation.Journal_volume 264 _Citation.Journal_issue 4 _Citation.Journal_ASTM . _Citation.Journal_ISSN . _Citation.Journal_CSD . _Citation.Book_title . _Citation.Book_chapter_title . _Citation.Book_volume . _Citation.Book_series . _Citation.Book_publisher . _Citation.Book_publisher_city . _Citation.Book_ISBN . _Citation.Conference_title . _Citation.Conference_site . _Citation.Conference_state_province . _Citation.Conference_country . _Citation.Conference_start_date . _Citation.Conference_end_date . _Citation.Conference_abstract_number . _Citation.Thesis_institution . _Citation.Thesis_institution_city . _Citation.Thesis_institution_country . _Citation.WWW_URL . _Citation.Page_first 2003 _Citation.Page_last 2012 _Citation.Year 1989 _Citation.Details . loop_ _Citation_author.Ordinal _Citation_author.Given_name _Citation_author.Family_name _Citation_author.First_initial _Citation_author.Middle_initials _Citation_author.Family_title _Citation_author.Entry_ID _Citation_author.Citation_ID 1 David Reid . G. . 2476 1 2 Martin Saunders . . . 2476 1 stop_ save_ ############################################# # Molecular system (assembly) description # ############################################# save_system_pancreatic_polypeptide _Assembly.Sf_category assembly _Assembly.Sf_framecode system_pancreatic_polypeptide _Assembly.Entry_ID 2476 _Assembly.ID 1 _Assembly.Name 'pancreatic polypeptide' _Assembly.BMRB_code . _Assembly.Number_of_components . _Assembly.Organic_ligands . _Assembly.Metal_ions . _Assembly.Non_standard_bonds . _Assembly.Ambiguous_conformational_states . _Assembly.Ambiguous_chem_comp_sites . _Assembly.Molecules_in_chemical_exchange . _Assembly.Paramagnetic . _Assembly.Thiol_state . _Assembly.Molecular_mass . _Assembly.Enzyme_commission_number . _Assembly.Details . _Assembly.DB_query_date . _Assembly.DB_query_revised_last_date . loop_ _Entity_assembly.ID _Entity_assembly.Entity_assembly_name _Entity_assembly.Entity_ID _Entity_assembly.Entity_label _Entity_assembly.Asym_ID _Entity_assembly.PDB_chain_ID _Entity_assembly.Experimental_data_reported _Entity_assembly.Physical_state _Entity_assembly.Conformational_isomer _Entity_assembly.Chemical_exchange_state _Entity_assembly.Magnetic_equivalence_group_code _Entity_assembly.Role _Entity_assembly.Details _Entity_assembly.Entry_ID _Entity_assembly.Assembly_ID 1 'pancreatic polypeptide' 1 $pancreatic_polypeptide . . . . . . . . . 2476 1 stop_ loop_ _Assembly_common_name.Name _Assembly_common_name.Type _Assembly_common_name.Entry_ID _Assembly_common_name.Assembly_ID 'pancreatic polypeptide' system 2476 1 stop_ save_ #################################### # Biological polymers and ligands # #################################### save_pancreatic_polypeptide _Entity.Sf_category entity _Entity.Sf_framecode pancreatic_polypeptide _Entity.Entry_ID 2476 _Entity.ID 1 _Entity.BMRB_code . _Entity.Name 'pancreatic polypeptide' _Entity.Type polymer _Entity.Polymer_common_type . _Entity.Polymer_type polypeptide(L) _Entity.Polymer_type_details . _Entity.Polymer_strand_ID . _Entity.Polymer_seq_one_letter_code_can ; GPTGTGESKCPLMVKVLDAV RGSPAINVAVHVFRKAADDT WEPFASGKTSESGELHGLTT EEEFVEGIYKVEIDTKSYWK ALGISPFHEHAEVVFTANDS GPRRYTIAALLSPYSYSTTA VVTNPKE ; _Entity.Polymer_seq_one_letter_code ; GPTGTGESKCPLMVKVLDAV RGSPAINVAVHVFRKAADDT WEPFASGKTSESGELHGLTT EEEFVEGIYKVEIDTKSYWK ALGISPFHEHAEVVFTANDS GPRRYTIAALLSPYSYSTTA VVTNPKE ; _Entity.Target_identifier . _Entity.Polymer_author_defined_seq . _Entity.Polymer_author_seq_details . _Entity.Ambiguous_conformational_states . _Entity.Ambiguous_chem_comp_sites . _Entity.Nstd_monomer . _Entity.Nstd_chirality . _Entity.Nstd_linkage . _Entity.Nonpolymer_comp_ID . _Entity.Nonpolymer_comp_label . _Entity.Number_of_monomers 127 _Entity.Number_of_nonpolymer_components . _Entity.Paramagnetic . _Entity.Thiol_state . _Entity.Src_method . _Entity.Parent_entity_ID 1 _Entity.Fragment . _Entity.Mutation . _Entity.EC_number . _Entity.Calc_isoelectric_point . _Entity.Formula_weight . _Entity.Formula_weight_exptl . _Entity.Formula_weight_exptl_meth . _Entity.Details . _Entity.DB_query_date . _Entity.DB_query_revised_last_date 2015-11-25 loop_ _Entity_db_link.Ordinal _Entity_db_link.Author_supplied _Entity_db_link.Database_code _Entity_db_link.Accession_code _Entity_db_link.Entry_mol_code _Entity_db_link.Entry_mol_name _Entity_db_link.Entry_experimental_method _Entity_db_link.Entry_structure_resolution _Entity_db_link.Entry_relation_type _Entity_db_link.Entry_details _Entity_db_link.Chimera_segment_ID _Entity_db_link.Seq_query_to_submitted_percent _Entity_db_link.Seq_subject_length _Entity_db_link.Seq_identity _Entity_db_link.Seq_positive _Entity_db_link.Seq_homology_expectation_val _Entity_db_link.Seq_align_begin _Entity_db_link.Seq_align_end _Entity_db_link.Seq_difference_details _Entity_db_link.Seq_alignment_details _Entity_db_link.Entry_ID _Entity_db_link.Entity_ID 1 no PDB 1BM7 . "Human Transthyretin (Prealbumin) Complex With Flufenamic Acid (2-[[3-(Trifluoromethyl)phenyl]amino] Benzoic Acid)" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 2 no PDB 1BMZ . "Human Transthyretin (Prealbumin)" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 3 no PDB 1BZ8 . "Transthyretin (Del Val122)" . . . . . 100.00 126 99.21 99.21 5.34e-84 . . . . 2476 1 4 no PDB 1BZD . "Tertiary Structures Of Three Amyloidogenic Transthyretin Variants And Implications For Amyloid Fibril Formation" . . . . . 100.00 127 99.21 99.21 1.11e-85 . . . . 2476 1 5 no PDB 1BZE . "Tertiary Structures Of Three Amyloidogenic Transthyretin Variants And Implications For Amyloid Fibril Formation" . . . . . 100.00 127 99.21 99.21 7.39e-86 . . . . 2476 1 6 no PDB 1DVQ . "Crystal Structure Of Human Transthyretin" . . . . . 97.64 124 99.19 100.00 8.45e-84 . . . . 2476 1 7 no PDB 1DVS . "Crystal Structure Of Human Transthyretin In Complex With Resveratrol" . . . . . 97.64 124 99.19 100.00 8.45e-84 . . . . 2476 1 8 no PDB 1DVT . "Crystal Structure Of Human Transthyretin In Complex With Flurbiprofen" . . . . . 97.64 124 99.19 100.00 8.45e-84 . . . . 2476 1 9 no PDB 1DVU . "Crystal Structure Of Human Transthyretin In Complex With Dibenzofuran- 4,6-Dicarboxylic Acid" . . . . . 97.64 124 99.19 100.00 8.45e-84 . . . . 2476 1 10 no PDB 1DVX . "Crystal Structure Of Human Transthyretin In Complex With Diclofenac" . . . . . 97.64 124 99.19 100.00 8.45e-84 . . . . 2476 1 11 no PDB 1DVY . "Crystal Structure Of Transthyretin In Complex With N-(M- Trifluoromethylphenyl) Phenoxazine-4,6-Dicarboxylic Acid" . . . . . 97.64 124 99.19 100.00 8.45e-84 . . . . 2476 1 12 no PDB 1DVZ . "Crystal Structure Of Human Transthyretin In Complex With O- Trifluoromethylphenyl Anthranilic Acid" . . . . . 97.64 124 99.19 100.00 8.45e-84 . . . . 2476 1 13 no PDB 1E3F . "Structure Of Human Transthyretin Complexed With Bromophenols: A New Mode Of Binding" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 14 no PDB 1E4H . "Structure Of Human Transthyretin Complexed With Bromophenols: A New Mode Of Binding" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 15 no PDB 1E5A . "Structure Of Human Transthyretin Complexed With Bromophenols: A New Mode Of Binding" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 16 no PDB 1ETA . "The X-Ray Crystal Structure Refinements Of Normal Human Transthyretin And The Amyloidogenic Val 30-->met Variant To 1.7 Angstro" . . . . . 100.79 128 99.22 99.22 8.71e-85 . . . . 2476 1 17 no PDB 1ETB . "The X-Ray Crystal Structure Refinements Of Normal Human Transthyretin And The Amyloidogenic Val 30-->met Variant To 1.7 Angstro" . . . . . 100.00 127 99.21 99.21 8.24e-86 . . . . 2476 1 18 no PDB 1F41 . "Crystal Structure Of Human Transthyretin At 1.5a Resolution" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 19 no PDB 1F86 . "Transthyretin Thr119met Protein Stabilisation" . . . . . 90.55 115 99.13 99.13 1.10e-76 . . . . 2476 1 20 no PDB 1FH2 . "Transthyretin Stability As A Key Factor In Amyloidogenesis" . . . . . 91.34 116 98.28 98.28 6.27e-73 . . . . 2476 1 21 no PDB 1FHN . "Transthyretin Stability As A Key Factor In Amyloidogenesis" . . . . . 100.00 127 99.21 99.21 7.39e-86 . . . . 2476 1 22 no PDB 1G1O . "Crystal Structure Of The Highly Amyloidogenic Transthyretin Mutant Ttr G53sE54DL55S" . . . . . 100.00 127 97.64 98.43 4.63e-84 . . . . 2476 1 23 no PDB 1GKO . "An Engineered Transthyretin Monomer That Is Non-Amyloidogenic - Unless Partially Denatured" . . . . . 100.00 127 98.43 99.21 1.39e-85 . . . . 2476 1 24 no PDB 1ICT . "Monoclinic Form Of Human Transthyretin Complexed With Thyroxine (T4)" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 25 no PDB 1III . "Crystal Structure Of The Transthyretin Mutant Ttr Y114c-data Collected At Room Temperature" . . . . . 100.00 127 99.21 99.21 3.76e-85 . . . . 2476 1 26 no PDB 1IIK . "Crystal Structure Of The Transthyretin Mutant Ttr Y114c-Data Collected At Cryo Temperature" . . . . . 100.00 127 99.21 99.21 3.76e-85 . . . . 2476 1 27 no PDB 1IJN . "Crystal Structure Of The Transthyretin Mutant Ttr C10aY114C" . . . . . 100.00 127 98.43 98.43 9.95e-84 . . . . 2476 1 28 no PDB 1QAB . "The Structure Of Human Retinol Binding Protein With Its Carrier Protein Transthyretin Reveals Interaction With The Carboxy Term" . . . . . 100.00 127 99.21 100.00 2.68e-86 . . . . 2476 1 29 no PDB 1QWH . "A Covalent Dimer Of Transthyretin That Affects The Amyloid Pathway" . . . . . 92.13 117 100.00 100.00 2.77e-78 . . . . 2476 1 30 no PDB 1RLB . "Retinol Binding Protein Complexed With Transthyretin" . . . . . 100.00 127 99.21 100.00 2.68e-86 . . . . 2476 1 31 no PDB 1SOK . "Crystal Structure Of The Transthyretin Mutant A108yL110E SOLVED IN Space Group P21212" . . . . . 100.00 127 98.43 98.43 2.16e-84 . . . . 2476 1 32 no PDB 1SOQ . "Crystal Structure Of The Transthyretin Mutant A108yL110E SOLVED IN Space Group C2" . . . . . 100.00 127 98.43 98.43 2.16e-84 . . . . 2476 1 33 no PDB 1THA . "Mechanism Of Molecular Recognition. Structural Aspects Of 3, 3'-Diiodo-L-Thyronine Binding To Human Serum Transthyretin" . . . . . 100.00 127 99.21 100.00 2.68e-86 . . . . 2476 1 34 no PDB 1THC . "Crystal Structure Determination At 2.3a Of Human Transthyretin-3',5'- Dibromo-2',4,4',6-Tetra-Hydroxyaurone Complex" . . . . . 100.00 127 99.21 100.00 2.68e-86 . . . . 2476 1 35 no PDB 1TLM . "Structural Aspects Of Inotropic Bipyridine Binding: Crystal Structure Determination To 1.9 Angstroms Of The Human Serum Transth" . . . . . 100.00 127 99.21 100.00 2.68e-86 . . . . 2476 1 36 no PDB 1TSH . "Tertiary Structures Of Three Amyloidogenic Transthyretin Variants And Implications For Amyloid Fibril Formation" . . . . . 100.00 127 99.21 99.21 7.07e-86 . . . . 2476 1 37 no PDB 1TT6 . "The Orthorhombic Crystal Structure Of Transthyretin In Complex With Diethylstilbestrol" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 38 no PDB 1TTA . "The X-Ray Crystal Structure Refinements Of Normal Human Transthyretin And The Amyloidogenic Val30met Variant To 1.7 Angstroms R" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 39 no PDB 1TTB . "The X-Ray Crystal Structure Refinements Of Normal Human Transthyretin And The Amyloidogenic Val30met Variant To 1.7 Angstroms R" . . . . . 100.00 127 99.21 99.21 8.24e-86 . . . . 2476 1 40 no PDB 1TTC . "The X-Ray Crystal Structure Refinements Of Normal Human Transthyretin And The Amyloidogenic Val30met Variant To 1.7 Angstroms R" . . . . . 100.00 127 99.21 100.00 4.01e-86 . . . . 2476 1 41 no PDB 1TTR . "Transthyretin-V122I CARDIOMYOPATHIC MUTANT" . . . . . 100.00 127 99.21 100.00 2.59e-86 . . . . 2476 1 42 no PDB 1TYR . "Transthyretin Complex With Retinoic Acid" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 43 no PDB 1TZ8 . "The Monoclinic Crystal Struture Of Transthyretin In Complex With Diethylstilbestrol" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 44 no PDB 1U21 . "Transthyretin With Tethered Inhibitor On One Monomer." . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 45 no PDB 1X7S . "The X-Ray Crystallographic Structure Of The Amyloidogenic Variant Ttr Tyr78phe" . . . . . 100.00 127 99.21 100.00 5.44e-86 . . . . 2476 1 46 no PDB 1X7T . "Structure Of Ttr R104h: A Non-Amyloidogenic Variant With Protective Clinical Effects" . . . . . 100.00 127 99.21 99.21 1.83e-85 . . . . 2476 1 47 no PDB 1Y1D . "Crystal Structure Of Transthyretin In Complex With Iododiflunisal" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 48 no PDB 1Z7J . "Human Transthyretin (Also Called Prealbumin) Complex With 3, 3',5,5'- Tetraiodothyroacetic Acid (T4ac)" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 49 no PDB 1ZCR . "Crystal Structure Of Human Transthyretin With Bound Iodide" . . . . . 100.00 128 100.00 100.00 1.32e-86 . . . . 2476 1 50 no PDB 1ZD6 . "Crystal Structure Of Human Transthyretin With Bound Chloride" . . . . . 100.00 128 100.00 100.00 1.32e-86 . . . . 2476 1 51 no PDB 2B14 . "The Crystal Structure Of 2,4-Dinitrophenol In Complex With The Amyloidogenic Variant Transthyretin Leu 55 Pro" . . . . . 100.00 127 99.21 99.21 3.76e-85 . . . . 2476 1 52 no PDB 2B15 . "The Crystal Structure Of 2,4-Dinitrophenol In Complex With Human Transthyretin" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 53 no PDB 2B16 . "The Crystal Structure Of 2,4-Dinitrophenol In Complex With The Amyloidogenic Variant Transthyretin Tyr78phe" . . . . . 100.00 127 99.21 100.00 5.44e-86 . . . . 2476 1 54 no PDB 2B77 . "Human Transthyretin (ttr) Complexed With Diflunisal Analogues- Ttr.2', 4'-dichloro-4-hydroxy-1,1'-biphenyl-3-carboxylic Acid" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 55 no PDB 2B9A . "Human Transthyretin (ttr) Complexed With Diflunisal Analogues- Ttr.3', 5'-difluorobiphenyl-4-carboxylic Acid" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 56 no PDB 2F7I . "Human Transthyretin (Ttr) Complexed With Diflunisal Analogues- Ttr. 2',6'-Difluorobiphenyl-4-Carboxylic Acid" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 57 no PDB 2F8I . "Human Transthyretin (Ttr) Complexed With Benzoxazole" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 58 no PDB 2FBR . "Human Transthyretin (Ttr) Complexed With Bivalant Amyloid Inhibitor (4 Carbon Linker)" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 59 no PDB 2FLM . "Human Transthyretin (Ttr) Complexed With Bivalant Amyloid Inhibitor (6 Carbon Linker)" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 60 no PDB 2G3X . "Crystal Structure Of Transthyretin Mutant I84s At Acidic Ph" . . . . . 100.00 127 99.21 99.21 1.60e-85 . . . . 2476 1 61 no PDB 2G3Z . "Crystal Structure Of Transthyretin Mutant I84a At Low Ph" . . . . . 100.00 127 99.21 99.21 1.09e-85 . . . . 2476 1 62 no PDB 2G4E . "Crystal Structure Of Transthyretin Mutant I84a At Neutral Ph" . . . . . 100.00 127 99.21 99.21 1.09e-85 . . . . 2476 1 63 no PDB 2G4G . "Crystal Structure Of Human Transthyretin At Ph 4.6" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 64 no PDB 2G5U . "Human Transthyretin (Ttr) Complexed With Hydroxylated Polychlorinated Biphenyl-4,4'-Dihydroxy-3,3',5,5'-Tetrachlorobiphenyl" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 65 no PDB 2G9K . "Human Transthyretin (Ttr) Complexed With Hydroxylated Polychlorinated Biphenyl-4-Hydroxy-2',3,3',4',5-Pentachlorobiphenyl" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 66 no PDB 2GAB . "Human Transthyretin (Ttr) Complexed With Hydroxylated Polychlorinated Biphenyl-4-Hydroxy-3,3',5,4'-Tetrachlorobiphenyl" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 67 no PDB 2H4E . "Crystal Structure Of Cys10 Sulfonated Transthyretin" . . . . . 100.00 127 99.21 99.21 5.88e-85 . . . . 2476 1 68 no PDB 2NOY . "Crystal Structure Of Transthyretin Mutant I84s At Ph 7.5" . . . . . 100.00 127 99.21 99.21 1.60e-85 . . . . 2476 1 69 no PDB 2PAB . "Structure Of Prealbumin, Secondary, Tertiary And Quaternary Interactions Determined By Fourier Refinement At 1.8 Angstroms" . . . . . 100.00 127 99.21 100.00 2.68e-86 . . . . 2476 1 70 no PDB 2QEL . "Crystal Structure Of The Highly Amyloidogenic Transthyretin Mutant Ttr G53s/e54d/l55s- Heated Protein" . . . . . 100.00 127 97.64 98.43 4.63e-84 . . . . 2476 1 71 no PDB 2QGB . "Human Transthyretin (Ttr) In Apo-Form" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 72 no PDB 2QGC . "Human Transthyretin (Ttr) Complexed With 2-(3,5-Dimethyl-4- Hydroxyphenyl)benzoxazole" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 73 no PDB 2QGD . "Human Transthyretin (Ttr) Complexed With 2-(3,5-Dibromo-4- Hydroxyphenyl)benzoxazole" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 74 no PDB 2QGE . "Human Transthyretin (Ttr) Complexed With 2-(3,5-Dimethylphenyl) Benzoxazole" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 75 no PDB 2ROX . "Transthyretin (Also Called Prealbumin) Complex With Thyroxine (T4)" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 76 no PDB 2ROY . "Transthyretin (Also Called Prealbumin) Complex With 3',5'-Dinitro-N- Acetyl-L-Thyronine" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 77 no PDB 2TRH . "Tertiary Structures Of Three Amyloidogenic Transthyretin Variants And Implications For Amyloid Fibril Formation" . . . . . 100.00 127 99.21 99.21 1.07e-84 . . . . 2476 1 78 no PDB 2TRY . "Tertiary Structures Of Three Amyloidogenic Transthyretin Variants And Implications For Amyloid Fibril Formation" . . . . . 100.00 127 99.21 99.21 1.62e-85 . . . . 2476 1 79 no PDB 2WQA . "Complex Of Ttr And Rbp4 And Oleic Acid" . . . . . 100.00 129 100.00 100.00 2.08e-86 . . . . 2476 1 80 no PDB 3A4D . "Crystal Structure Of Human Transthyretin (Wild-Type)" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 81 no PDB 3A4E . "Crystal Structure Of Human Transthyretin (e54g)" . . . . . 100.00 127 99.21 99.21 2.11e-85 . . . . 2476 1 82 no PDB 3A4F . "Crystal Structure Of Human Transthyretin (e54k)" . . . . . 100.00 127 99.21 100.00 5.21e-86 . . . . 2476 1 83 no PDB 3B56 . "Crystal Structure Of Transthyretin In Complex With 3,5- Diiodosalicylic Acid" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 84 no PDB 3BSZ . "Crystal Structure Of The Transthyretin-retinol Binding Protein-fab Complex" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 85 no PDB 3BT0 . "Crystal Structure Of Transthyretin Variant V20s" . . . . . 100.00 127 99.21 99.21 1.07e-85 . . . . 2476 1 86 no PDB 3CBR . "Crystal Structure Of Human Transthyretin (Ttr) At Ph3.5" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 87 no PDB 3CFM . "Crystal Structure Of The Apo Form Of Human Wild-Type Transthyretin" . . . . . 92.91 118 100.00 100.00 8.23e-80 . . . . 2476 1 88 no PDB 3CFN . "Crystal Structure Of Human Transthyretin In Complex With 1-Anilino-8- Naphthalene Sulfonate" . . . . . 92.91 118 100.00 100.00 8.23e-80 . . . . 2476 1 89 no PDB 3CFQ . "Crystal Structure Of Human Wild-Type Transthyretin In Complex With Diclofenac" . . . . . 92.91 118 100.00 100.00 8.23e-80 . . . . 2476 1 90 no PDB 3CFT . "Crystal Structure Of Human Transthyretin In Complex With 1- Amino-5-Naphthalene Sulfonate" . . . . . 92.91 118 100.00 100.00 8.23e-80 . . . . 2476 1 91 no PDB 3CN0 . "Human Transthyretin (Ttr) In Complex With 3,5-Dimethyl-4- Hydroxystilbene" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 92 no PDB 3CN1 . "Human Transthyretin (Ttr) In Complex With 3,5-Dibromo-4- Hydroxystilbene" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 93 no PDB 3CN2 . "Human Transthyretin (Ttr) In Complex With 3,5-Dibromo-4- Hydroxybiphenyl" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 94 no PDB 3CN3 . "Human Transthyretin (Ttr) In Complex With 1,3-Dibromo-2- Hydroxy-5-Phenoxybenzene" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 95 no PDB 3CN4 . "Human Transthyretin (Ttr) In Complex With N-(3,5-Dibromo-4- Hydroxyphenyl)benzamide" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 96 no PDB 3CXF . "Crystal Structure Of Transthyretin Variant Y114h" . . . . . 100.00 127 99.21 100.00 1.09e-85 . . . . 2476 1 97 no PDB 3D2T . "Human Transthyretin (ttr) Complexed With Diflunisal" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 98 no PDB 3D7P . "Crystal Structure Of Human Transthyretin (Ttr) At Ph 4.0" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 99 no PDB 3DGD . "Crystal Structure Of The F87mL110M MUTANT OF HUMAN TRANSTHYRETIN AT Ph 4.6" . . . . . 100.00 127 98.43 99.21 1.39e-85 . . . . 2476 1 100 no PDB 3DID . "Crystal Structure Of The F87mL110M MUTANT OF HUMAN TRANSTHYRETIN AT Ph 4.6 Soaked" . . . . . 100.00 127 98.43 99.21 1.39e-85 . . . . 2476 1 101 no PDB 3DJR . "Crystal Structure Of Transthyretin Variant L58h At Neutral Ph" . . . . . 100.00 127 99.21 99.21 2.89e-85 . . . . 2476 1 102 no PDB 3DJS . "Crystal Structure Of Transthyretin Variant L58h At Acidic Ph" . . . . . 100.00 127 99.21 99.21 2.89e-85 . . . . 2476 1 103 no PDB 3DJT . "Crystal Structure Of Transthyretin Variant V30m At Acidic Ph" . . . . . 100.00 127 99.21 100.00 4.01e-86 . . . . 2476 1 104 no PDB 3DJZ . "Crystal Structure Of Transthyretin Variant L55p At Neutral Ph" . . . . . 100.00 127 99.21 99.21 3.76e-85 . . . . 2476 1 105 no PDB 3DK0 . "Crystal Structure Of Transthyretin Variant L55p At Acidic Ph" . . . . . 100.00 127 99.21 99.21 3.76e-85 . . . . 2476 1 106 no PDB 3DK2 . "Crystal Structure Of Transthyretin Variant Y114h At Acidic Ph" . . . . . 100.00 127 99.21 100.00 1.09e-85 . . . . 2476 1 107 no PDB 3DO4 . "Crystal Structure Of Transthyretin Variant T60a At Acidic Ph" . . . . . 100.00 127 99.21 99.21 7.07e-86 . . . . 2476 1 108 no PDB 3ESN . "Human Transthyretin (Ttr) Complexed With N-(3,5-Dibromo-4- Hydroxyphenyl)-2,6-Dimethylbenzamide" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 109 no PDB 3ESO . "Human Transthyretin (Ttr) Complexed With N-(3,5-Dibromo-4- Hydroxyphenyl)-2,5-Dichlorobenzamide" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 110 no PDB 3ESP . "Human Transthyretin (Ttr) Complexed With N-(3,5-Dibromo-4- Hydroxyphenyl)-3,5-Dimethyl-4-Hydroxybenzamide" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 111 no PDB 3FC8 . "Crystal Structure Of Transthyretin In Complex With Iododiflunisal-Betaalaome" . . . . . 97.64 124 100.00 100.00 4.25e-84 . . . . 2476 1 112 no PDB 3FCB . "Crystal Structure Of Transthyretin In Complex With Iododiflunisal-Betaalaoh" . . . . . 97.64 124 100.00 100.00 4.25e-84 . . . . 2476 1 113 no PDB 3GLZ . "Human Transthyretin (Ttr) Complexed With(E)-3-(2- (Trifluoromethyl)benzylideneaminooxy)propanoic Acid (Inhibitor 11)" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 114 no PDB 3GPS . "Crystal Structure Of The F87mL110M MUTANT OF HUMAN TRANSTHYRETIN AT Ph 5.5" . . . . . 100.00 127 98.43 99.21 1.39e-85 . . . . 2476 1 115 no PDB 3GRB . "Crystal Structure Of The F87mL110M MUTANT OF HUMAN TRANSTHYRETIN AT Ph 6.5" . . . . . 100.00 127 98.43 99.21 1.39e-85 . . . . 2476 1 116 no PDB 3GRG . "Crystal Structure Of The F87mL110M MUTANT OF HUMAN TRANSTHYRETIN AT Ph 7.5" . . . . . 100.00 127 98.43 99.21 1.39e-85 . . . . 2476 1 117 no PDB 3GS0 . "Human Transthyretin (Ttr) Complexed With (S)-3-(9h-Fluoren- 9-Ylideneaminooxy)-2-Methylpropanoic Acid (Inhibitor 16)" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 118 no PDB 3GS4 . "Human Transthyretin (Ttr) Complexed With 3-(9h-Fluoren-9- Ylideneaminooxy)propanoic Acid (Inhibitor 15)" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 119 no PDB 3GS7 . "Human Transthyretin (Ttr) Complexed With (E)-3-(2- Methoxybenzylideneaminooxy)propanoic Acid (Inhibitor 13)" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 120 no PDB 3HJ0 . "Transthyretin In Complex With A Covalent Small Molecule Kinetic Stabilizer" . . . . . 100.00 127 99.21 99.21 5.88e-85 . . . . 2476 1 121 no PDB 3I9A . "Crystal Structure Of Human Transthyretin Variant A25t - #1" . . . . . 100.00 127 99.21 99.21 8.24e-86 . . . . 2476 1 122 no PDB 3I9I . "Crystal Structure Of Human Transthyretin Variant A25t - #2" . . . . . 91.34 116 99.14 99.14 1.20e-77 . . . . 2476 1 123 no PDB 3I9P . "Crystal Structure Of Human Transthyretin - Wild Type" . . . . . 91.34 116 100.00 100.00 2.80e-78 . . . . 2476 1 124 no PDB 3IMR . "Transthyretin In Complex With (E)-2,6-Dibromo-4-(2,6- Dichlorostyryl)phenol" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 125 no PDB 3IMS . "Transthyretin In Complex With 2,6-Dibromo-4-(2,6- Dichlorophenethyl)phenol" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 126 no PDB 3IMT . "Transthyretin In Complex With (E)-4-(4-Aminostyryl)-2,6- Dibromophenol" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 127 no PDB 3IMU . "Transthyretin In Complex With (E)-4-(3-Aminostyryl)-2,6- Dibromoaniline" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 128 no PDB 3IMV . "Transthyretin In Complex With (E)-4-(4-Aminostyryl)-2,6- Dibromoaniline" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 129 no PDB 3IMW . "Transthyretin In Complex With (E)-2,6-Dibromo-4-(2,6- Dimethoxystyryl)aniline" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 130 no PDB 3IPB . "Human Transthyretin (Ttr) Complexed With A Palindromic Bivalent Amyloid Inhibitor (11 Carbon Linker)." . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 131 no PDB 3IPE . "Human Transthyretin (Ttr) Complexed With A Palindromic Bivalent Amyloid Inhibitor (7 Carbon Linker)." . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 132 no PDB 3KGS . "V30m Mutant Human Transthyretin (Ttr) (Apov30m) Ph 7.5" . . . . . 100.00 127 99.21 100.00 4.01e-86 . . . . 2476 1 133 no PDB 3KGT . "V30m Mutant Human Transthyretin (Ttr) Complexed With Geniste (V30m:gen) Ph 7.5" . . . . . 100.00 127 99.21 100.00 4.01e-86 . . . . 2476 1 134 no PDB 3KGU . "Wild Type Human Transthyretin (Ttr) Complexed With Genistein (Ttrwt:gen) Ph 7.5" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 135 no PDB 3M1O . "Human Transthyretin (Ttr) Complexed With 2-((3,5-Dichloro-4- Hydroxyphenyl)amino)benzoic Acid" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 136 no PDB 3NEE . "Wild Type Human Transthyretin (Ttr) Complexed With Gc-1 (Ttrwt:gc-1)" . . . . . 91.34 116 100.00 100.00 2.80e-78 . . . . 2476 1 137 no PDB 3NEO . "Wild Type Human Transthyretin (Ttr) Complexed With Gc-24 (Ttrwt:gc-24)" . . . . . 91.34 116 100.00 100.00 2.80e-78 . . . . 2476 1 138 no PDB 3NES . "V30m Mutant Human Transthyretin (Ttr) Complexed With Gc-1 (V30m:gc-1)" . . . . . 91.34 116 99.14 100.00 6.93e-78 . . . . 2476 1 139 no PDB 3NEX . "V30m Mutant Human Transthyretin (Ttr) Complexed With Gc-24 (V30m:gc- 24)" . . . . . 91.34 116 99.14 100.00 6.93e-78 . . . . 2476 1 140 no PDB 3NG5 . "Crystal Structure Of V30m Transthyretin Complexed With (-)- Epigallocatechin Gallate (Egcg)" . . . . . 100.00 127 99.21 100.00 4.01e-86 . . . . 2476 1 141 no PDB 3OZK . "Crystal Structure Of Human Transthyretin Variant A25t In Complex With Thyroxine (T4)" . . . . . 100.00 127 99.21 99.21 8.24e-86 . . . . 2476 1 142 no PDB 3OZL . "Crystal Structure Of Human Transthyretin Variant A25t In Complex With Flufenamic Acid" . . . . . 100.00 127 99.21 99.21 8.24e-86 . . . . 2476 1 143 no PDB 3P3R . "Transthyretin In Complex With (3,4-Dihydroxy-5-Nitrophenyl)(2- Fluorophenyl)methanone" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 144 no PDB 3P3S . "Human Transthyretin (Ttr) Complexed With (Z)-5-(3,5-Dibromo-4- Hydroxybenzylidene)-Imino-1-Methylimidazolidin-4-One" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 145 no PDB 3P3T . "Human Transthyretin (Ttr) Complexed With 4-(3-(2-Flourophenoxy) Propyl)-3,5-Dimethyl-1h-Pyrazole" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 146 no PDB 3P3U . "Human Transthyretin (Ttr) Complexed With 5-(2-Ethoxyphenyl)-3- (Pyridin-4-Yl)-1,2,4-Oxadiazole" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 147 no PDB 3SSG . "Structure Of Transthyretin L55p In Complex With Zn" . . . . . 100.00 127 99.21 99.21 3.76e-85 . . . . 2476 1 148 no PDB 3TCT . "Structure Of Wild-Type Ttr In Complex With Tafamidis" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 149 no PDB 3TFB . "Transthyretin Natural Mutant A25t" . . . . . 91.34 116 99.14 99.14 1.20e-77 . . . . 2476 1 150 no PDB 3U2I . "X-Ray Crystal Structure Of Human Transthyretin At Room Temperature" . . . . . 91.34 117 100.00 100.00 2.15e-77 . . . . 2476 1 151 no PDB 3U2J . "Neutron Crystal Structure Of Human Transthyretin" . . . . . 91.34 117 100.00 100.00 2.15e-77 . . . . 2476 1 152 no PDB 3W3B . "Crystal Structure Of Wild-type Human Transthyretin" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 153 no PDB 4ABQ . "Crystal Structure Of Transthyretin In Complex With Ligand C-1" . . . . . 97.64 124 100.00 100.00 4.25e-84 . . . . 2476 1 154 no PDB 4ABU . "Crystal Structure Of Transthyretin In Complex With Ligand C-2" . . . . . 97.64 124 100.00 100.00 4.25e-84 . . . . 2476 1 155 no PDB 4ABV . "Crystal Structure Of Transthyretin In Complex With Ligand C-3" . . . . . 97.64 124 100.00 100.00 4.25e-84 . . . . 2476 1 156 no PDB 4ABW . "Crystal Structure Of Transthyretin In Complex With Ligand C-6" . . . . . 97.64 124 100.00 100.00 4.25e-84 . . . . 2476 1 157 no PDB 4AC2 . "Crystal Structure Of Transthyretin In Complex With Ligand C-7" . . . . . 97.64 124 100.00 100.00 4.25e-84 . . . . 2476 1 158 no PDB 4AC4 . "Crystal Structure Of Transthyretin In Complex With Ligand C-18" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 159 no PDB 4ACT . "Crystal Structure Of Transthyretin In Complex With Ligand C-17" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 160 no PDB 4ANK . "Crystallographic Study Of Novel Transthyretin Ligands Exhibiting Negative-Cooperativity Between Two T4 Binding Sites." . . . . . 100.00 147 100.00 100.00 1.09e-86 . . . . 2476 1 161 no PDB 4DER . "Crystal Structure Of The Wild Type Ttr Binding Apigenin (Ttrwt:api)" . . . . . 91.34 116 100.00 100.00 2.80e-78 . . . . 2476 1 162 no PDB 4DES . "Crystal Structure Of The Wild Type Ttr Binding Chrysin (Ttrwt:chr)" . . . . . 91.34 116 100.00 100.00 2.80e-78 . . . . 2476 1 163 no PDB 4DET . "Crystal Structure Of The Wild Type Ttr Binding Kaempferol (Ttrwt:kae)" . . . . . 91.34 116 100.00 100.00 2.80e-78 . . . . 2476 1 164 no PDB 4DEU . "Crystal Structure Of The Wild Type Ttr Binding Naringenin (Ttrwt:nar)" . . . . . 91.34 117 100.00 100.00 2.57e-78 . . . . 2476 1 165 no PDB 4DEW . "Crystal Structure Of The Wild Type Ttr Binding Luteolin (Ttrwt:lut)" . . . . . 100.00 147 100.00 100.00 1.09e-86 . . . . 2476 1 166 no PDB 4FI6 . "Kinetic Stabilization Of Transthyretin Through Covalent Modification Of K15 By 3-(5-(3,5-dichlorophenyl)-1,3,4-oxadiazol-2-yl)-" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 167 no PDB 4FI7 . "Kinetic Stabilization Of Transthyretin Through Covalent Modification Of K15 By 3-(5-(3,5-dichloro-4-hydroxyphenyl)-1,3,4-oxadia" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 168 no PDB 4FI8 . "Kinetic Stabilization Of Transthyretin Through Covalent Modification Of K15 By 4-bromo-3-(5-(3,5-dichloro-4-hydroxyphenyl)-1,3," . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 169 no PDB 4HIQ . "The Structure Of V122i Mutant Transthyretin In Complex With Ag10" . . . . . 100.00 127 99.21 100.00 2.59e-86 . . . . 2476 1 170 no PDB 4HIS . "The Structure Of V122i Mutant Transthyretin In Complex With Tafamidis" . . . . . 100.00 127 99.21 100.00 2.59e-86 . . . . 2476 1 171 no PDB 4HJS . "Kinetic Stabilization Of Transthyretin Through Covalent Modification Of K15 By (e)-n-(4-(4-hydroxy-3,5-dimethylstyryl)ethanesul" . . . . . 91.34 116 100.00 100.00 2.80e-78 . . . . 2476 1 172 no PDB 4HJT . "Kinetic Stabilization Of Transthyretin Through Covalent Modification Of K15 By (e)-n-(4-(4-hydroxy-3,5-dimethylstyryl)phenyl)pr" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 173 no PDB 4HJU . "Transthyretin In Complex With (e)-n-(3-(4-hydroxy-3,5-dimethylstyryl) Phenyl)acrylamide" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 174 no PDB 4I85 . "Crystal Structure Of Transthyretin In Complex With Chf5074 At Neutral Ph" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 175 no PDB 4I87 . "Crystal Structure Of Ttr Variant I84s In Complex With Chf5074 At Acidic Ph" . . . . . 100.00 127 99.21 99.21 1.60e-85 . . . . 2476 1 176 no PDB 4I89 . "Crystal Structure Of Transthyretin In Complex With Diflunisal At Acidic Ph" . . . . . 100.00 127 99.21 99.21 1.60e-85 . . . . 2476 1 177 no PDB 4IIZ . "Crystal Structure Of Wild-type Human Transthyretin In Complex With Lumiracoxib" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 178 no PDB 4IK6 . "Crystal Structure Of Human Transthyretin In Complex With Lumiracoxib" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 179 no PDB 4IK7 . "Crystal Structure Of Human Transthyretin In Complex With Indomethacin" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 180 no PDB 4IKI . "Crystal Structure Of Wild-type Human Transthyretin In Complex With Indomethacin" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 181 no PDB 4IKJ . "Crystal Structure Of Wild-type Human Transthyretin In Complex With Sulindac" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 182 no PDB 4IKK . "Crystal Structure Of Wild-type Human Transthyretin In Complex With Sulindac" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 183 no PDB 4IKL . "Crystal Structure Of Wild-type Human Transthyretin In Complex With Sulindac" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 184 no PDB 4KY2 . "Transthyretin In Complex With The Fluorescent Folding Sensor (e)-7- Hydroxy-3-(4-hydroxy-3,5-dimethylstyryl)-4-methyl-2h-chrome" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 185 no PDB 4L1S . "Covalent Modification Of Transthyretin K15 By Yielding The Fluorescent Conjugate (e)-3-(dimethylamino)-5-(4-hydroxy-3,5-dimethy" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 186 no PDB 4L1T . "Transthyretin In Complex With (e)-3-(dimethylamino)-5-(4-hydroxy-3,5- Dimethylstyryl)benzoic Acid" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 187 no PDB 4MAS . "High Resolution Structure Of Wild Type Human Transthyretin In Complex With 3,3',5,5'-tetrachloro-[1,1'-biphenyl]-4,4'diol" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 188 no PDB 4MRB . "Wild Type Human Transthyretin Ph 7.5" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 189 no PDB 4MRC . "Human Transthyretin Ser52pro Mutant" . . . . . 99.21 126 99.21 99.21 1.05e-84 . . . . 2476 1 190 no PDB 4N85 . "Crystal Structure Of Human Transthyretin" . . . . . 100.00 159 100.00 100.00 2.09e-86 . . . . 2476 1 191 no PDB 4N86 . "Crystal Structure Of Human Transthyretin Complexed With Glabridin" . . . . . 100.00 159 100.00 100.00 2.09e-86 . . . . 2476 1 192 no PDB 4N87 . "Crystal Structure Of V30m Mutant Human Transthyretin Complexed With Glabridin" . . . . . 100.00 159 99.21 100.00 4.53e-86 . . . . 2476 1 193 no PDB 4PM1 . "Human Transthyretin (ttr) Complexed With 16-alpha-bromo-estradiol" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 194 no PDB 4PME . "Human Transthyretin (ttr) Complexed With Ferulic Acid And Curcumin" . . . . . 92.91 118 100.00 100.00 6.62e-80 . . . . 2476 1 195 no PDB 4PMF . "Human Transthyretin (ttr) Complexed With Curcumin" . . . . . 92.13 117 100.00 100.00 4.99e-79 . . . . 2476 1 196 no PDB 4PVL . "X-ray Structure Of Human Transthyretin (ttr) At Room Temperature To 1.9a Resolution" . . . . . 100.00 130 100.00 100.00 1.69e-86 . . . . 2476 1 197 no PDB 4PVM . "Neutron Structure Of Human Transthyretin (ttr) At Room Temperature To 2.0a Resolution (laue)" . . . . . 100.00 130 100.00 100.00 1.69e-86 . . . . 2476 1 198 no PDB 4PVN . "Neutron Structure Of Human Transthyretin (ttr) At Room Temperature To 2.3a Resolution (monochromatic)" . . . . . 100.00 130 100.00 100.00 1.69e-86 . . . . 2476 1 199 no PDB 4PWE . "Crystal Structure Of V30m Mutant Human Transthyretin" . . . . . 100.00 159 99.21 100.00 4.53e-86 . . . . 2476 1 200 no PDB 4PWF . "Crystal Structure Of V30m Mutant Human Transthyretin Complexed With Ferulic Acid Phenethyl Ester" . . . . . 100.00 159 99.21 100.00 4.53e-86 . . . . 2476 1 201 no PDB 4PWG . "Crystal Structure Of V30m Mutant Human Transthyretin Complexed With Caffeic Acid Ethyl Ester" . . . . . 100.00 159 99.21 100.00 4.53e-86 . . . . 2476 1 202 no PDB 4PWH . "Crystal Structure Of V30m Mutant Human Transthyretin Complexed With Caffeic Acid 1,1-dimethylallyl Ester" . . . . . 100.00 159 99.21 100.00 4.53e-86 . . . . 2476 1 203 no PDB 4PWI . "Crystal Structure Of V30m Mutant Human Transthyretin Complexed With Rosmarinic Acid" . . . . . 100.00 159 99.21 100.00 4.53e-86 . . . . 2476 1 204 no PDB 4PWJ . "Crystal Structure Of V30m Mutant Human Transthyretin Complexed With Nordihydroguaiaretic Acid" . . . . . 100.00 159 99.21 100.00 4.53e-86 . . . . 2476 1 205 no PDB 4PWK . "Crystal Structure Of V30m Mutant Human Transthyretin Complexed With Dihydroguaiaretic Acid" . . . . . 100.00 159 99.21 100.00 4.53e-86 . . . . 2476 1 206 no PDB 4QRF . "Crystal Structure Of V30m Mutant Human Transthyretin Complexed With Caffeic Acid Phenethyl Ester" . . . . . 100.00 159 99.21 100.00 4.53e-86 . . . . 2476 1 207 no PDB 4QXV . "Crystal Structure Of Human Transthyretin In Complex With Luteolin At 1.1 A Resolution" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 208 no PDB 4QYA . "Crystal Structure Of Human Transthyretin Variant V30m In Complex With Luteolin" . . . . . 100.00 127 99.21 100.00 4.01e-86 . . . . 2476 1 209 no PDB 4TKW . "Crystal Sructure Of Human Transthyretin Leu55pro Mutant" . . . . . 93.70 125 99.16 99.16 5.30e-79 . . . . 2476 1 210 no PDB 4TL4 . "Crystal Structure Of Human Transthyretin Val30met Mutant" . . . . . 93.70 125 99.16 100.00 6.74e-80 . . . . 2476 1 211 no PDB 4TL5 . "Crystal Structure Of Human Transthyretin Ser85pro Mutant" . . . . . 93.70 125 99.16 99.16 2.44e-79 . . . . 2476 1 212 no PDB 4TLK . "Crystal Structure Of Human Transthyretin Ser85pro/glu92pro Mutant" . . . . . 93.70 125 98.32 98.32 2.55e-78 . . . . 2476 1 213 no PDB 4TLS . "Crystal Structure Of Human Transthyretin Glu92pro Mutant" . . . . . 93.70 125 99.16 99.16 3.46e-79 . . . . 2476 1 214 no PDB 4TLT . "Crystal Structure Of Human Transthyretin" . . . . . 93.70 125 99.16 99.16 1.07e-78 . . . . 2476 1 215 no PDB 4TM9 . "Crystal Structure Of Human Transthyretin Thr119trp Mutant" . . . . . 93.70 125 99.16 99.16 4.03e-79 . . . . 2476 1 216 no PDB 4TNE . "Crystal Structure Of Human Transthyretin Thr119tyr Mutant" . . . . . 93.70 125 99.16 99.16 2.26e-79 . . . . 2476 1 217 no PDB 4TQ8 . "Dual Binding Mode For 3-(9h-fluoren-9-ylideneaminooxy)propanoic Acid Binding To Human Transthyretin (ttr)" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 218 no PDB 4TQH . "Human Transthyretin (ttr) Complexed With 3-(9h-fluoren-9- Ylideneaminooxy)ethanoic Acid" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 219 no PDB 4TQI . "Human Transthyretin (ttr) Complexed With 3-(9h-fluoren-9- Ylideneaminooxy)propanoic Acid In A Dual Binding Mode" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 220 no PDB 4TQP . "Human Transthyretin (ttr) Complexed With (r)-3-(9h-fluoren-9- Ylideneaminooxy)-2-methyl-n-(methylsulfonyl) Propionamide In A Du" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 221 no PDB 4WNJ . "Crystal Structure Of Transthyretin-quercetin Complex" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 222 no PDB 4WNS . "Crystal Structure Of Transthyretin Complexed With Pterostilbene" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 223 no PDB 4WO0 . "Crystal Structure Of Transthyretin In Complex With Apigenin" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 224 no PDB 4Y9B . "Crystal Structure Of V30m Mutated Transthyretin In Complex With Alpha- Mangostin" . . . . . 100.00 159 99.21 100.00 4.53e-86 . . . . 2476 1 225 no PDB 4Y9C . "Crystal Structure Of V30m Mutated Transthyretin With Bromide In Complex With Alpha-mangostin" . . . . . 100.00 159 99.21 100.00 4.53e-86 . . . . 2476 1 226 no PDB 4Y9E . "Crystal Structure Of V30m Mutated Transthyretin In Complex With Gamma- Mangostin" . . . . . 100.00 159 99.21 100.00 4.53e-86 . . . . 2476 1 227 no PDB 4Y9F . "Crystal Structure Of V30m Mutated Transthyretin With Bromide In Complex With Gamma-mangostin" . . . . . 100.00 159 99.21 100.00 4.53e-86 . . . . 2476 1 228 no PDB 4Y9G . "Crystal Structure Of V30m Mutated Transthyretin In Complex With 3- Isomangostin" . . . . . 100.00 159 99.21 100.00 4.53e-86 . . . . 2476 1 229 no PDB 4YDM . "High Resolution Crystal Structure Of Human Transthyretin Bound To Ligand And Conjugates Of 3-(5-(3,5-dichloro-4-hydroxyphenyl)-" . . . . . 100.00 127 99.21 99.21 1.50e-85 . . . . 2476 1 230 no PDB 4YDN . "High Resolution Crystal Structure Of Human Transthyretin Bound To Ligand And Conjugates Of 4-(5-(3,5-dichloro-4-hydroxyphenyl)-" . . . . . 100.00 127 99.21 99.21 1.50e-85 . . . . 2476 1 231 no PDB 5AKS . "Transthyretin Binding Heterogeneity And Anti-amyloidogenic Activity Of Natural Polyphenols And Their Metabolites: Resveratrol-3" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 232 no PDB 5AKT . "Transthyretin Binding Heterogeneity And Anti-amyloidogenic Activity Of Natural Polyphenols And Their Metabolites: Resveratrol-4" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 233 no PDB 5AKV . "Transthyretin Binding Heterogeneity And Anti-amyloidogenic Activity Of Natural Polyphenols And Their Metabolites: Genistein-7-o" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 234 no PDB 5AL0 . "Transthyretin Binding Heterogeneity And Anti-amyloidogenic Activity Of Natural Polyphenols And Their Metabolites: Resveratrol-3" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 235 no PDB 5AL8 . "Transthyretin Binding Heterogeneity And Anti-amyloidogenic Activity Of Natural Polyphenols And Their Metabolites: Daidzein-7-o-" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 236 no PDB 5BOJ . "Crystal Structure Of Human Transthyretin In Complex With Gemfibrozil" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 237 no PDB 5CR1 . "Crystal Structure Of Ttr/resveratrol/t4 Complex" . . . . . 91.34 116 99.14 99.14 3.02e-77 . . . . 2476 1 238 no PDB 5TTR . "Leu 55 Pro Transthyretin Crystal Structure" . . . . . 100.00 127 99.21 99.21 3.76e-85 . . . . 2476 1 239 no DBJ BAA00059 . "prealbumin [Homo sapiens]" . . . . . 100.00 147 99.21 100.00 2.35e-86 . . . . 2476 1 240 no DBJ BAF62350 . "transthyretin [Pan troglodytes verus]" . . . . . 100.00 147 97.64 99.21 4.43e-84 . . . . 2476 1 241 no DBJ BAG34987 . "unnamed protein product [Homo sapiens]" . . . . . 100.00 147 100.00 100.00 1.09e-86 . . . . 2476 1 242 no EMBL CAA42087 . "transthyretin [Homo sapiens]" . . . . . 100.00 147 100.00 100.00 1.09e-86 . . . . 2476 1 243 no EMBL CAG33189 . "TTR [Homo sapiens]" . . . . . 100.00 147 99.21 100.00 3.71e-86 . . . . 2476 1 244 no GB AAA60011 . "prealbumin [Homo sapiens]" . . . . . 100.00 147 100.00 100.00 1.09e-86 . . . . 2476 1 245 no GB AAA60012 . "prealbumin [Homo sapiens]" . . . . . 100.00 147 100.00 100.00 1.09e-86 . . . . 2476 1 246 no GB AAA60013 . "prealbumin precursor, partial [Homo sapiens]" . . . . . 100.00 147 100.00 100.00 1.09e-86 . . . . 2476 1 247 no GB AAA60018 . "prealbumin [Homo sapiens]" . . . . . 100.00 147 99.21 100.00 2.35e-86 . . . . 2476 1 248 no GB AAA61181 . "transthyretin, partial [Homo sapiens]" . . . . . 92.13 117 100.00 100.00 2.77e-78 . . . . 2476 1 249 no PRF 0908191A . "prealbumin,thyroxine binding" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 250 no PRF 1008142A . "prealbumin variant" . . . . . 100.00 127 98.43 99.21 1.57e-84 . . . . 2476 1 251 no PRF 1101213A . "protein,amyloid fibril" . . . . . 100.00 127 100.00 100.00 1.39e-86 . . . . 2476 1 252 no PRF 1709210A . transthyretin . . . . . 100.00 147 100.00 100.00 1.09e-86 . . . . 2476 1 253 no REF NP_000362 . "transthyretin precursor [Homo sapiens]" . . . . . 100.00 147 100.00 100.00 1.09e-86 . . . . 2476 1 254 no REF NP_001009137 . "transthyretin precursor [Pan troglodytes]" . . . . . 100.00 147 97.64 99.21 4.43e-84 . . . . 2476 1 255 no REF XP_003830303 . "PREDICTED: transthyretin [Pan paniscus]" . . . . . 100.00 148 97.64 99.21 5.10e-84 . . . . 2476 1 256 no SP P02766 . "RecName: Full=Transthyretin; AltName: Full=ATTR; AltName: Full=Prealbumin; AltName: Full=TBPA; Flags: Precursor" . . . . . 100.00 147 100.00 100.00 1.09e-86 . . . . 2476 1 257 no SP Q5U7I5 . "RecName: Full=Transthyretin; AltName: Full=Prealbumin; Flags: Precursor" . . . . . 100.00 147 97.64 99.21 4.43e-84 . . . . 2476 1 stop_ loop_ _Entity_common_name.Name _Entity_common_name.Type _Entity_common_name.Entry_ID _Entity_common_name.Entity_ID 'pancreatic polypeptide' common 2476 1 prealbumin variant 2476 1 stop_ loop_ _Entity_comp_index.ID _Entity_comp_index.Auth_seq_ID _Entity_comp_index.Comp_ID _Entity_comp_index.Comp_label _Entity_comp_index.Entry_ID _Entity_comp_index.Entity_ID 1 . GLY . 2476 1 2 . PRO . 2476 1 3 . THR . 2476 1 4 . GLY . 2476 1 5 . THR . 2476 1 6 . GLY . 2476 1 7 . GLU . 2476 1 8 . SER . 2476 1 9 . LYS . 2476 1 10 . CYS . 2476 1 11 . PRO . 2476 1 12 . LEU . 2476 1 13 . MET . 2476 1 14 . VAL . 2476 1 15 . LYS . 2476 1 16 . VAL . 2476 1 17 . LEU . 2476 1 18 . ASP . 2476 1 19 . ALA . 2476 1 20 . VAL . 2476 1 21 . ARG . 2476 1 22 . GLY . 2476 1 23 . SER . 2476 1 24 . PRO . 2476 1 25 . ALA . 2476 1 26 . ILE . 2476 1 27 . ASN . 2476 1 28 . VAL . 2476 1 29 . ALA . 2476 1 30 . VAL . 2476 1 31 . HIS . 2476 1 32 . VAL . 2476 1 33 . PHE . 2476 1 34 . ARG . 2476 1 35 . LYS . 2476 1 36 . ALA . 2476 1 37 . ALA . 2476 1 38 . ASP . 2476 1 39 . ASP . 2476 1 40 . THR . 2476 1 41 . TRP . 2476 1 42 . GLU . 2476 1 43 . PRO . 2476 1 44 . PHE . 2476 1 45 . ALA . 2476 1 46 . SER . 2476 1 47 . GLY . 2476 1 48 . LYS . 2476 1 49 . THR . 2476 1 50 . SER . 2476 1 51 . GLU . 2476 1 52 . SER . 2476 1 53 . GLY . 2476 1 54 . GLU . 2476 1 55 . LEU . 2476 1 56 . HIS . 2476 1 57 . GLY . 2476 1 58 . LEU . 2476 1 59 . THR . 2476 1 60 . THR . 2476 1 61 . GLU . 2476 1 62 . GLU . 2476 1 63 . GLU . 2476 1 64 . PHE . 2476 1 65 . VAL . 2476 1 66 . GLU . 2476 1 67 . GLY . 2476 1 68 . ILE . 2476 1 69 . TYR . 2476 1 70 . LYS . 2476 1 71 . VAL . 2476 1 72 . GLU . 2476 1 73 . ILE . 2476 1 74 . ASP . 2476 1 75 . THR . 2476 1 76 . LYS . 2476 1 77 . SER . 2476 1 78 . TYR . 2476 1 79 . TRP . 2476 1 80 . LYS . 2476 1 81 . ALA . 2476 1 82 . LEU . 2476 1 83 . GLY . 2476 1 84 . ILE . 2476 1 85 . SER . 2476 1 86 . PRO . 2476 1 87 . PHE . 2476 1 88 . HIS . 2476 1 89 . GLU . 2476 1 90 . HIS . 2476 1 91 . ALA . 2476 1 92 . GLU . 2476 1 93 . VAL . 2476 1 94 . VAL . 2476 1 95 . PHE . 2476 1 96 . THR . 2476 1 97 . ALA . 2476 1 98 . ASN . 2476 1 99 . ASP . 2476 1 100 . SER . 2476 1 101 . GLY . 2476 1 102 . PRO . 2476 1 103 . ARG . 2476 1 104 . ARG . 2476 1 105 . TYR . 2476 1 106 . THR . 2476 1 107 . ILE . 2476 1 108 . ALA . 2476 1 109 . ALA . 2476 1 110 . LEU . 2476 1 111 . LEU . 2476 1 112 . SER . 2476 1 113 . PRO . 2476 1 114 . TYR . 2476 1 115 . SER . 2476 1 116 . TYR . 2476 1 117 . SER . 2476 1 118 . THR . 2476 1 119 . THR . 2476 1 120 . ALA . 2476 1 121 . VAL . 2476 1 122 . VAL . 2476 1 123 . THR . 2476 1 124 . ASN . 2476 1 125 . PRO . 2476 1 126 . LYS . 2476 1 127 . GLU . 2476 1 stop_ loop_ _Entity_poly_seq.Hetero _Entity_poly_seq.Mon_ID _Entity_poly_seq.Num _Entity_poly_seq.Comp_index_ID _Entity_poly_seq.Entry_ID _Entity_poly_seq.Entity_ID . GLY 1 1 2476 1 . PRO 2 2 2476 1 . THR 3 3 2476 1 . GLY 4 4 2476 1 . THR 5 5 2476 1 . GLY 6 6 2476 1 . GLU 7 7 2476 1 . SER 8 8 2476 1 . LYS 9 9 2476 1 . CYS 10 10 2476 1 . PRO 11 11 2476 1 . LEU 12 12 2476 1 . MET 13 13 2476 1 . VAL 14 14 2476 1 . LYS 15 15 2476 1 . VAL 16 16 2476 1 . LEU 17 17 2476 1 . ASP 18 18 2476 1 . ALA 19 19 2476 1 . VAL 20 20 2476 1 . ARG 21 21 2476 1 . GLY 22 22 2476 1 . SER 23 23 2476 1 . PRO 24 24 2476 1 . ALA 25 25 2476 1 . ILE 26 26 2476 1 . ASN 27 27 2476 1 . VAL 28 28 2476 1 . ALA 29 29 2476 1 . VAL 30 30 2476 1 . HIS 31 31 2476 1 . VAL 32 32 2476 1 . PHE 33 33 2476 1 . ARG 34 34 2476 1 . LYS 35 35 2476 1 . ALA 36 36 2476 1 . ALA 37 37 2476 1 . ASP 38 38 2476 1 . ASP 39 39 2476 1 . THR 40 40 2476 1 . TRP 41 41 2476 1 . GLU 42 42 2476 1 . PRO 43 43 2476 1 . PHE 44 44 2476 1 . ALA 45 45 2476 1 . SER 46 46 2476 1 . GLY 47 47 2476 1 . LYS 48 48 2476 1 . THR 49 49 2476 1 . SER 50 50 2476 1 . GLU 51 51 2476 1 . SER 52 52 2476 1 . GLY 53 53 2476 1 . GLU 54 54 2476 1 . LEU 55 55 2476 1 . HIS 56 56 2476 1 . GLY 57 57 2476 1 . LEU 58 58 2476 1 . THR 59 59 2476 1 . THR 60 60 2476 1 . GLU 61 61 2476 1 . GLU 62 62 2476 1 . GLU 63 63 2476 1 . PHE 64 64 2476 1 . VAL 65 65 2476 1 . GLU 66 66 2476 1 . GLY 67 67 2476 1 . ILE 68 68 2476 1 . TYR 69 69 2476 1 . LYS 70 70 2476 1 . VAL 71 71 2476 1 . GLU 72 72 2476 1 . ILE 73 73 2476 1 . ASP 74 74 2476 1 . THR 75 75 2476 1 . LYS 76 76 2476 1 . SER 77 77 2476 1 . TYR 78 78 2476 1 . TRP 79 79 2476 1 . LYS 80 80 2476 1 . ALA 81 81 2476 1 . LEU 82 82 2476 1 . GLY 83 83 2476 1 . ILE 84 84 2476 1 . SER 85 85 2476 1 . PRO 86 86 2476 1 . PHE 87 87 2476 1 . HIS 88 88 2476 1 . GLU 89 89 2476 1 . HIS 90 90 2476 1 . ALA 91 91 2476 1 . GLU 92 92 2476 1 . VAL 93 93 2476 1 . VAL 94 94 2476 1 . PHE 95 95 2476 1 . THR 96 96 2476 1 . ALA 97 97 2476 1 . ASN 98 98 2476 1 . ASP 99 99 2476 1 . SER 100 100 2476 1 . GLY 101 101 2476 1 . PRO 102 102 2476 1 . ARG 103 103 2476 1 . ARG 104 104 2476 1 . TYR 105 105 2476 1 . THR 106 106 2476 1 . ILE 107 107 2476 1 . ALA 108 108 2476 1 . ALA 109 109 2476 1 . LEU 110 110 2476 1 . LEU 111 111 2476 1 . SER 112 112 2476 1 . PRO 113 113 2476 1 . TYR 114 114 2476 1 . SER 115 115 2476 1 . TYR 116 116 2476 1 . SER 117 117 2476 1 . THR 118 118 2476 1 . THR 119 119 2476 1 . ALA 120 120 2476 1 . VAL 121 121 2476 1 . VAL 122 122 2476 1 . THR 123 123 2476 1 . ASN 124 124 2476 1 . PRO 125 125 2476 1 . LYS 126 126 2476 1 . GLU 127 127 2476 1 stop_ save_ #################### # Natural source # #################### save_natural_source _Entity_natural_src_list.Sf_category natural_source _Entity_natural_src_list.Sf_framecode natural_source _Entity_natural_src_list.Entry_ID 2476 _Entity_natural_src_list.ID 1 loop_ _Entity_natural_src.ID _Entity_natural_src.Entity_ID _Entity_natural_src.Entity_label _Entity_natural_src.Entity_chimera_segment_ID _Entity_natural_src.NCBI_taxonomy_ID _Entity_natural_src.Type _Entity_natural_src.Common _Entity_natural_src.Organism_name_scientific _Entity_natural_src.Organism_name_common _Entity_natural_src.Organism_acronym _Entity_natural_src.ICTVdb_decimal_code _Entity_natural_src.Superkingdom _Entity_natural_src.Kingdom _Entity_natural_src.Genus _Entity_natural_src.Species _Entity_natural_src.Strain _Entity_natural_src.Variant _Entity_natural_src.Subvariant _Entity_natural_src.Organ _Entity_natural_src.Tissue _Entity_natural_src.Tissue_fraction _Entity_natural_src.Cell_line _Entity_natural_src.Cell_type _Entity_natural_src.ATCC_number _Entity_natural_src.Organelle _Entity_natural_src.Cellular_location _Entity_natural_src.Fragment _Entity_natural_src.Fraction _Entity_natural_src.Secretion _Entity_natural_src.Plasmid _Entity_natural_src.Plasmid_details _Entity_natural_src.Gene_mnemonic _Entity_natural_src.Dev_stage _Entity_natural_src.Details _Entity_natural_src.Citation_ID _Entity_natural_src.Citation_label _Entity_natural_src.Entry_ID _Entity_natural_src.Entity_natural_src_list_ID 1 1 $pancreatic_polypeptide . 9606 organism . 'Homo sapiens' human . . Eukaryota Metazoa Homo sapiens generic . . . . . . . . . . . . . . . . . . . . 2476 1 stop_ save_ ######################### # Experimental source # ######################### save_experimental_source _Entity_experimental_src_list.Sf_category experimental_source _Entity_experimental_src_list.Sf_framecode experimental_source _Entity_experimental_src_list.Entry_ID 2476 _Entity_experimental_src_list.ID 1 loop_ _Entity_experimental_src.ID _Entity_experimental_src.Entity_ID _Entity_experimental_src.Entity_label _Entity_experimental_src.Entity_chimera_segment_ID _Entity_experimental_src.Production_method _Entity_experimental_src.Host_org_scientific_name _Entity_experimental_src.Host_org_name_common _Entity_experimental_src.Host_org_details _Entity_experimental_src.Host_org_NCBI_taxonomy_ID _Entity_experimental_src.Host_org_genus _Entity_experimental_src.Host_org_species _Entity_experimental_src.Host_org_strain _Entity_experimental_src.Host_org_variant _Entity_experimental_src.Host_org_subvariant _Entity_experimental_src.Host_org_organ _Entity_experimental_src.Host_org_tissue _Entity_experimental_src.Host_org_tissue_fraction _Entity_experimental_src.Host_org_cell_line _Entity_experimental_src.Host_org_cell_type _Entity_experimental_src.Host_org_cellular_location _Entity_experimental_src.Host_org_organelle _Entity_experimental_src.Host_org_gene _Entity_experimental_src.Host_org_culture_collection _Entity_experimental_src.Host_org_ATCC_number _Entity_experimental_src.Vector_type _Entity_experimental_src.PDBview_host_org_vector_name _Entity_experimental_src.PDBview_plasmid_name _Entity_experimental_src.Vector_name _Entity_experimental_src.Vector_details _Entity_experimental_src.Vendor_name _Entity_experimental_src.Host_org_dev_stage _Entity_experimental_src.Details _Entity_experimental_src.Citation_ID _Entity_experimental_src.Citation_label _Entity_experimental_src.Entry_ID _Entity_experimental_src.Entity_experimental_src_list_ID 1 1 $pancreatic_polypeptide . 'not available' . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2476 1 stop_ save_ ##################################### # Sample contents and methodology # ##################################### ######################## # Sample description # ######################## save_sample_one _Sample.Sf_category sample _Sample.Sf_framecode sample_one _Sample.Entry_ID 2476 _Sample.ID 1 _Sample.Type solution _Sample.Sub_type . _Sample.Details . _Sample.Aggregate_sample_number . _Sample.Solvent_system . _Sample.Preparation_date . _Sample.Preparation_expiration_date . _Sample.Polycrystallization_protocol . _Sample.Single_crystal_protocol . _Sample.Crystal_grow_apparatus . _Sample.Crystal_grow_atmosphere . _Sample.Crystal_grow_details . _Sample.Crystal_grow_method . _Sample.Crystal_grow_method_cit_ID . _Sample.Crystal_grow_pH . _Sample.Crystal_grow_pH_range . _Sample.Crystal_grow_pressure . _Sample.Crystal_grow_pressure_esd . _Sample.Crystal_grow_seeding . _Sample.Crystal_grow_seeding_cit_ID . _Sample.Crystal_grow_temp . _Sample.Crystal_grow_temp_details . _Sample.Crystal_grow_temp_esd . _Sample.Crystal_grow_time . _Sample.Oriented_sample_prep_protocol . _Sample.Lyophilization_cryo_protectant . _Sample.Storage_protocol . save_ ####################### # Sample conditions # ####################### save_sample_condition_set_one _Sample_condition_list.Sf_category sample_conditions _Sample_condition_list.Sf_framecode sample_condition_set_one _Sample_condition_list.Entry_ID 2476 _Sample_condition_list.ID 1 _Sample_condition_list.Details . loop_ _Sample_condition_variable.Type _Sample_condition_variable.Val _Sample_condition_variable.Val_err _Sample_condition_variable.Val_units _Sample_condition_variable.Entry_ID _Sample_condition_variable.Sample_condition_list_ID pH 7.4 . na 2476 1 temperature 353 . K 2476 1 stop_ save_ ######################### # Experimental detail # ######################### ################################## # NMR Spectrometer definitions # ################################## save_spectrometer_list _NMR_spectrometer.Sf_category NMR_spectrometer _NMR_spectrometer.Sf_framecode spectrometer_list _NMR_spectrometer.Entry_ID 2476 _NMR_spectrometer.ID 1 _NMR_spectrometer.Details 'spectrometer information not available' _NMR_spectrometer.Manufacturer unknown _NMR_spectrometer.Model unknown _NMR_spectrometer.Serial_number . _NMR_spectrometer.Field_strength 0 save_ save_NMR_spectrometer_list _NMR_spectrometer_list.Sf_category NMR_spectrometer_list _NMR_spectrometer_list.Sf_framecode NMR_spectrometer_list _NMR_spectrometer_list.Entry_ID 2476 _NMR_spectrometer_list.ID 1 loop_ _NMR_spectrometer_view.ID _NMR_spectrometer_view.Name _NMR_spectrometer_view.Manufacturer _NMR_spectrometer_view.Model _NMR_spectrometer_view.Serial_number _NMR_spectrometer_view.Field_strength _NMR_spectrometer_view.Details _NMR_spectrometer_view.Citation_ID _NMR_spectrometer_view.Citation_label _NMR_spectrometer_view.Entry_ID _NMR_spectrometer_view.NMR_spectrometer_list_ID 1 spectrometer_1 unknown unknown . 0 'spectrometer information not available' . . 2476 1 stop_ save_ ############################# # NMR applied experiments # ############################# save_experiment_list _Experiment_list.Sf_category experiment_list _Experiment_list.Sf_framecode experiment_list _Experiment_list.Entry_ID 2476 _Experiment_list.ID 1 _Experiment_list.Details . loop_ _Experiment.ID _Experiment.Name _Experiment.Raw_data_flag _Experiment.NMR_spec_expt_ID _Experiment.NMR_spec_expt_label _Experiment.MS_expt_ID _Experiment.MS_expt_label _Experiment.SAXS_expt_ID _Experiment.SAXS_expt_label _Experiment.FRET_expt_ID _Experiment.FRET_expt_label _Experiment.EMR_expt_ID _Experiment.EMR_expt_label _Experiment.Sample_ID _Experiment.Sample_label _Experiment.Sample_state _Experiment.Sample_volume _Experiment.Sample_volume_units _Experiment.Sample_condition_list_ID _Experiment.Sample_condition_list_label _Experiment.Sample_spinning_rate _Experiment.Sample_angle _Experiment.NMR_tube_type _Experiment.NMR_spectrometer_ID _Experiment.NMR_spectrometer_label _Experiment.NMR_spectrometer_probe_ID _Experiment.NMR_spectrometer_probe_label _Experiment.NMR_spectral_processing_ID _Experiment.NMR_spectral_processing_label _Experiment.Mass_spectrometer_ID _Experiment.Mass_spectrometer_label _Experiment.Xray_instrument_ID _Experiment.Xray_instrument_label _Experiment.Fluorescence_instrument_ID _Experiment.Fluorescence_instrument_label _Experiment.EMR_instrument_ID _Experiment.EMR_instrument_label _Experiment.Chromatographic_system_ID _Experiment.Chromatographic_system_label _Experiment.Chromatographic_column_ID _Experiment.Chromatographic_column_label _Experiment.Entry_ID _Experiment.Experiment_list_ID 1 . . . . . . . . . . . . 1 $sample_one . . . 1 $sample_condition_set_one . . . 1 $spectrometer_list . . . . . . . . . . . . . . . . 2476 1 stop_ save_ #################### # NMR parameters # #################### ############################## # Assigned chemical shifts # ############################## ################################ # Chemical shift referencing # ################################ save_chem_shift_reference_par_set_one _Chem_shift_reference.Sf_category chem_shift_reference _Chem_shift_reference.Sf_framecode chem_shift_reference_par_set_one _Chem_shift_reference.Entry_ID 2476 _Chem_shift_reference.ID 1 _Chem_shift_reference.Details . loop_ _Chem_shift_ref.Atom_type _Chem_shift_ref.Atom_isotope_number _Chem_shift_ref.Mol_common_name _Chem_shift_ref.Atom_group _Chem_shift_ref.Concentration_val _Chem_shift_ref.Concentration_units _Chem_shift_ref.Solvent _Chem_shift_ref.Rank _Chem_shift_ref.Chem_shift_units _Chem_shift_ref.Chem_shift_val _Chem_shift_ref.Ref_method _Chem_shift_ref.Ref_type _Chem_shift_ref.Indirect_shift_ratio _Chem_shift_ref.External_ref_loc _Chem_shift_ref.External_ref_sample_geometry _Chem_shift_ref.External_ref_axis _Chem_shift_ref.Indirect_shift_ratio_cit_ID _Chem_shift_ref.Indirect_shift_ratio_cit_label _Chem_shift_ref.Ref_correction_type _Chem_shift_ref.Correction_val _Chem_shift_ref.Correction_val_cit_ID _Chem_shift_ref.Correction_val_cit_label _Chem_shift_ref.Entry_ID _Chem_shift_ref.Chem_shift_reference_ID H . DSS . . . . . ppm 0 . . . . . . 1 $entry_citation . . 1 $entry_citation 2476 1 stop_ save_ ################################### # Assigned chemical shift lists # ################################### ################################################################### # Chemical Shift Ambiguity Index Value Definitions # # # # The values other than 1 are used for those atoms with different # # chemical shifts that cannot be assigned to stereospecific atoms # # or to specific residues or chains. # # # # Index Value Definition # # # # 1 Unique (including isolated methyl protons, # # geminal atoms, and geminal methyl # # groups with identical chemical shifts) # # (e.g. ILE HD11, HD12, HD13 protons) # # 2 Ambiguity of geminal atoms or geminal methyl # # proton groups (e.g. ASP HB2 and HB3 # # protons, LEU CD1 and CD2 carbons, or # # LEU HD11, HD12, HD13 and HD21, HD22, # # HD23 methyl protons) # # 3 Aromatic atoms on opposite sides of # # symmetrical rings (e.g. TYR HE1 and HE2 # # protons) # # 4 Intraresidue ambiguities (e.g. LYS HG and # # HD protons or TRP HZ2 and HZ3 protons) # # 5 Interresidue ambiguities (LYS 12 vs. LYS 27) # # 6 Intermolecular ambiguities (e.g. ASP 31 CA # # in monomer 1 and ASP 31 CA in monomer 2 # # of an asymmetrical homodimer, duplex # # DNA assignments, or other assignments # # that may apply to atoms in one or more # # molecule in the molecular assembly) # # 9 Ambiguous, specific ambiguity not defined # # # ################################################################### save_chemical_shift_assignment_data_set_one _Assigned_chem_shift_list.Sf_category assigned_chemical_shifts _Assigned_chem_shift_list.Sf_framecode 'chemical_shift_assignment_data_set_one' _Assigned_chem_shift_list.Entry_ID 2476 _Assigned_chem_shift_list.ID 1 _Assigned_chem_shift_list.Sample_condition_list_ID 1 _Assigned_chem_shift_list.Sample_condition_list_label $sample_condition_set_one _Assigned_chem_shift_list.Chem_shift_reference_ID 1 _Assigned_chem_shift_list.Chem_shift_reference_label $chem_shift_reference_par_set_one _Assigned_chem_shift_list.Chem_shift_1H_err . _Assigned_chem_shift_list.Chem_shift_13C_err . _Assigned_chem_shift_list.Chem_shift_15N_err . _Assigned_chem_shift_list.Chem_shift_31P_err . _Assigned_chem_shift_list.Chem_shift_2H_err . _Assigned_chem_shift_list.Chem_shift_19F_err . _Assigned_chem_shift_list.Error_derivation_method . _Assigned_chem_shift_list.Details . _Assigned_chem_shift_list.Text_data_format . _Assigned_chem_shift_list.Text_data . loop_ _Chem_shift_experiment.Experiment_ID _Chem_shift_experiment.Experiment_name _Chem_shift_experiment.Sample_ID _Chem_shift_experiment.Sample_label _Chem_shift_experiment.Sample_state _Chem_shift_experiment.Entry_ID _Chem_shift_experiment.Assigned_chem_shift_list_ID . . 1 $sample_one . 2476 1 stop_ loop_ _Atom_chem_shift.ID _Atom_chem_shift.Assembly_atom_ID _Atom_chem_shift.Entity_assembly_ID _Atom_chem_shift.Entity_ID _Atom_chem_shift.Comp_index_ID _Atom_chem_shift.Seq_ID _Atom_chem_shift.Comp_ID _Atom_chem_shift.Atom_ID _Atom_chem_shift.Atom_type _Atom_chem_shift.Atom_isotope_number _Atom_chem_shift.Val _Atom_chem_shift.Val_err _Atom_chem_shift.Assign_fig_of_merit _Atom_chem_shift.Ambiguity_code _Atom_chem_shift.Occupancy _Atom_chem_shift.Resonance_ID _Atom_chem_shift.Auth_entity_assembly_ID _Atom_chem_shift.Auth_asym_ID _Atom_chem_shift.Auth_seq_ID _Atom_chem_shift.Auth_comp_ID _Atom_chem_shift.Auth_atom_ID _Atom_chem_shift.Details _Atom_chem_shift.Entry_ID _Atom_chem_shift.Assigned_chem_shift_list_ID 1 . 1 1 22 22 GLY HA2 H 1 4.15 . . 1 . . . . . . . . 2476 1 2 . 1 1 22 22 GLY HA3 H 1 4.15 . . 1 . . . . . . . . 2476 1 3 . 1 1 33 33 PHE HA H 1 5.23 . . 1 . . . . . . . . 2476 1 4 . 1 1 33 33 PHE HD1 H 1 7.6 . . 1 . . . . . . . . 2476 1 5 . 1 1 33 33 PHE HD2 H 1 7.6 . . 1 . . . . . . . . 2476 1 6 . 1 1 33 33 PHE HE1 H 1 7.6 . . 1 . . . . . . . . 2476 1 7 . 1 1 33 33 PHE HE2 H 1 7.6 . . 1 . . . . . . . . 2476 1 8 . 1 1 41 41 TRP HE3 H 1 7.6 . . 1 . . . . . . . . 2476 1 9 . 1 1 41 41 TRP HH2 H 1 7.22 . . 1 . . . . . . . . 2476 1 10 . 1 1 64 64 PHE HA H 1 4.86 . . 1 . . . . . . . . 2476 1 11 . 1 1 64 64 PHE HD1 H 1 7.22 . . 1 . . . . . . . . 2476 1 12 . 1 1 64 64 PHE HD2 H 1 7.22 . . 1 . . . . . . . . 2476 1 13 . 1 1 64 64 PHE HE1 H 1 6.72 . . 1 . . . . . . . . 2476 1 14 . 1 1 64 64 PHE HE2 H 1 6.72 . . 1 . . . . . . . . 2476 1 15 . 1 1 75 75 THR HG21 H 1 1.06 . . 1 . . . . . . . . 2476 1 16 . 1 1 75 75 THR HG22 H 1 1.06 . . 1 . . . . . . . . 2476 1 17 . 1 1 75 75 THR HG23 H 1 1.06 . . 1 . . . . . . . . 2476 1 18 . 1 1 78 78 TYR HD1 H 1 5.63 . . 1 . . . . . . . . 2476 1 19 . 1 1 78 78 TYR HD2 H 1 5.63 . . 1 . . . . . . . . 2476 1 20 . 1 1 78 78 TYR HE1 H 1 6.43 . . 1 . . . . . . . . 2476 1 21 . 1 1 78 78 TYR HE2 H 1 6.43 . . 1 . . . . . . . . 2476 1 22 . 1 1 79 79 TRP HZ2 H 1 7.46 . . 1 . . . . . . . . 2476 1 23 . 1 1 79 79 TRP HH2 H 1 7.12 . . 1 . . . . . . . . 2476 1 24 . 1 1 87 87 PHE HD1 H 1 6.83 . . 1 . . . . . . . . 2476 1 25 . 1 1 87 87 PHE HD2 H 1 6.83 . . 1 . . . . . . . . 2476 1 26 . 1 1 87 87 PHE HE1 H 1 7.22 . . 1 . . . . . . . . 2476 1 27 . 1 1 87 87 PHE HE2 H 1 7.22 . . 1 . . . . . . . . 2476 1 28 . 1 1 105 105 TYR HD1 H 1 7.12 . . 1 . . . . . . . . 2476 1 29 . 1 1 105 105 TYR HD2 H 1 7.12 . . 1 . . . . . . . . 2476 1 30 . 1 1 105 105 TYR HE1 H 1 7.22 . . 1 . . . . . . . . 2476 1 31 . 1 1 105 105 TYR HE2 H 1 7.22 . . 1 . . . . . . . . 2476 1 32 . 1 1 111 111 LEU HD11 H 1 .28 . . 1 . . . . . . . . 2476 1 33 . 1 1 111 111 LEU HD12 H 1 .28 . . 1 . . . . . . . . 2476 1 34 . 1 1 111 111 LEU HD13 H 1 .28 . . 1 . . . . . . . . 2476 1 35 . 1 1 111 111 LEU HD21 H 1 .28 . . 1 . . . . . . . . 2476 1 36 . 1 1 111 111 LEU HD22 H 1 .28 . . 1 . . . . . . . . 2476 1 37 . 1 1 111 111 LEU HD23 H 1 .28 . . 1 . . . . . . . . 2476 1 38 . 1 1 112 112 SER HA H 1 5.23 . . 1 . . . . . . . . 2476 1 39 . 1 1 114 114 TYR HD1 H 1 6.83 . . 1 . . . . . . . . 2476 1 40 . 1 1 114 114 TYR HD2 H 1 6.83 . . 1 . . . . . . . . 2476 1 41 . 1 1 120 120 ALA HA H 1 4.03 . . 1 . . . . . . . . 2476 1 42 . 1 1 120 120 ALA HB1 H 1 .18 . . 1 . . . . . . . . 2476 1 43 . 1 1 120 120 ALA HB2 H 1 .18 . . 1 . . . . . . . . 2476 1 44 . 1 1 120 120 ALA HB3 H 1 .18 . . 1 . . . . . . . . 2476 1 45 . 1 1 122 122 VAL HG11 H 1 .34 . . 1 . . . . . . . . 2476 1 46 . 1 1 122 122 VAL HG12 H 1 .34 . . 1 . . . . . . . . 2476 1 47 . 1 1 122 122 VAL HG13 H 1 .34 . . 1 . . . . . . . . 2476 1 48 . 1 1 122 122 VAL HG21 H 1 .34 . . 1 . . . . . . . . 2476 1 49 . 1 1 122 122 VAL HG22 H 1 .34 . . 1 . . . . . . . . 2476 1 50 . 1 1 122 122 VAL HG23 H 1 .34 . . 1 . . . . . . . . 2476 1 stop_ save_